-
Eng C, Yoshino T, Ru?z-Garc?a E, Mostafa N, Cann CG, O'Brian B, Benny A, Perez RO, Cremolini C. Colorectal cancer. Lancet. 2024 Jul 20; 404(10449):294-310.
PMID: 38909621.
Citations:
1 Fields:
Translation:
Humans
-
Ramirez RA, Eng C. The developing role of theranostics in NETs. Lancet. 2024 Jun 29; 403(10446):2759-2761.
PMID: 38851204.
Citations: Fields:
Translation:
Humans
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Segal NH, Melero I, Moreno V, Steeghs N, Marabelle A, Rohrberg K, Rodriguez-Ruiz ME, Eder JP, Eng C, Manji GA, Waterkamp D, Leutgeb B, Bouseida S, Flinn N, Das Thakur M, Elze MC, Koeppen H, Jamois C, Martin-Facklam M, Lieu CH, Calvo E, Paz-Ares L, Tabernero J, Argil?s G. CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nat Commun. 2024 May 15; 15(1):4091.
PMID: 38750034; PMCID: PMC11096172.
Citations:
2 Fields:
Translation:
HumansCTClinical Trials
-
Dasari A, Eng C, Lonardi S, Garcia-Carbonero R, Masuishi T, Cremolini C, Ghiringhelli F, Hubbard J, Bekaii-Saab T, Jones J, Xu RH, Shen L, Xu J, Bai Y, Deng Y, Yuan Y, Wei W, Lin J, Chen L, Yang Z, Schelman WR, Qin S, Li J. CLO24-088: Efficacy of Fruquintinib in Less Heavily Pretreated Patients (Pts) With Metastatic Colorectal Cancer (mCRC): Profile-Matched Data From FRESCO and FRESCO-2. J Natl Compr Canc Netw. 2024 Apr 05; 22(2.5).
PMID: 38579793.
Citations: Fields:
Translation:
Humans
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LaPelusa M, Cann C, Ciombor KK, Eng C. Mutational Signature Changes in Patients With Metastatic Squamous Cell Carcinoma of the Anal Canal. Oncologist. 2024 Apr 04; 29(4):e475-e486.
PMID: 38103030; PMCID: PMC10994269.
-
Janczewski LM, Browner A, Cotler J, Nelson H, Ballman KV, LeBlanc M, Gollub MJ, Eng C, Brierley JD, Palefsky JM, Goldberg RM, Goodman KA, Washington MK, Asare EA, Palis B. Data-driven optimization of version 9 American Joint Committee on Cancer staging system for anal cancer. Cancer. 2024 May 01; 130(9):1702-1710.
PMID: 38140735.
-
Davies-Venn C, Dorth J, Garcia-Aguilar J, George M, Kreppel L, Meyer JE, Monzon J, Saltz L, Schrag D, Smith JJ, Kennecke HF, Auer R, Cho M, Dasari NA, Eng C, Goodman KA, Zell JA, Das P, National Cancer Institute Rectal-Anal Task Force. NCI Rectal-Anal Task Force consensus recommendations for design of clinical trials in rectal cancer. J Natl Cancer Inst. 2023 12 06; 115(12):1457-1464.
PMID: 37535679; PMCID: PMC11032701.
Citations: Fields:
Translation:
Humans
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Santos ES, Oliver TK, Lacchetti C, Geisel R, Wilfong LS, Fader AN, Eng C. Drug Shortages in Oncology: ASCO Clinical Guidance for Alternative Treatments. JCO Oncol Pract. 2024 01; 20(1):19-32.
PMID: 37963306.
Citations: Fields:
Translation:
Humans
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Rogers JE, Sirisaengtaksin A, Leung M, Morris VK, Xiao L, Huey R, Wolff R, Eng C, Vauthey JN, Tzeng CD, Johnson B. Hepatic Metastasectomy in Squamous Cell Carcinoma of the Anal Canal: A Case Series of a Curative Approach. Cancers (Basel). 2023 Jul 31; 15(15).
PMID: 37568706; PMCID: PMC10417325.
Citations:
-
Cann CG, LaPelusa MB, Cimino SK, Eng C. Molecular and genetic targets within metastatic colorectal cancer and associated novel treatment advancements. Front Oncol. 2023; 13:1176950.
PMID: 37409250; PMCID: PMC10319053.
Citations:
-
Dasari A, Lonardi S, Garcia-Carbonero R, Elez E, Yoshino T, Sobrero A, Yao J, Garc?a-Alfonso P, Kocsis J, Cubillo Gracian A, Sartore-Bianchi A, Satoh T, Randrian V, Tomasek J, Chong G, Paulson AS, Masuishi T, Jones J, Csoszi T, Cremolini C, Ghiringhelli F, Shergill A, Hochster HS, Krauss J, Bassam A, Ducreux M, Elme A, Faugeras L, Kasper S, Van Cutsem E, Arnold D, Nanda S, Yang Z, Schelman WR, Kania M, Tabernero J, Eng C, FRESCO-2 Study Investigators. Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study. Lancet. 2023 07 01; 402(10395):41-53.
PMID: 37331369.
Citations:
17 Fields:
Translation:
HumansCTClinical Trials
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Kelly RJ, Bever K, Chao J, Ciombor KK, Eng C, Fakih M, Goyal L, Hubbard J, Iyer R, Kemberling HT, Krishnamurthi S, Ku G, Mordecai MM, Morris VK, Paulson AS, Peterson V, Shah MA, Le DT. Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of gastrointestinal cancer. J Immunother Cancer. 2023 06; 11(6).
PMID: 37286304; PMCID: PMC10254964.
Citations:
4 Fields:
Translation:
Humans
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Shen JP, Yousef AM, Zeineddine FA, Zeineddine MA, Tidwell RS, Beaty KA, Scofield LC, Rafeeq S, Hornstein N, Lano E, Eng C, Matamoros A, Foo WC, Uppal A, Scally C, Mansfield P, Taggart M, Raghav KP, Overman MJ, Fournier K. Efficacy of Systemic Chemotherapy in Patients With Low-grade Mucinous Appendiceal Adenocarcinoma: A Randomized Crossover Trial. JAMA Netw Open. 2023 06 01; 6(6):e2316161.
PMID: 37261831; PMCID: PMC10236240.
Citations:
4 Fields:
Translation:
Humans
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Lopez G, Eng C, Overman M, Ramirez D, Liu W, Beinhorn C, Sumler P, Prinsloo S, Li Y, Chen M, Bruera E, Cohen L. Publisher Correction: A randomized pilot study of oncology massage to treat chemotherapy-induced peripheral neuropathy. Sci Rep. 2023 May 23; 13(1):8318.
PMID: 37221249; PMCID: PMC10205728.
-
Janczewski LM, Faski J, Nelson H, Gollub MJ, Eng C, Brierley JD, Palefsky JM, Goldberg RM, Washington MK, Asare EA, Goodman KA, American Joint Committee on Cancer Expert Panel on Cancers of the Lower Gastrointestinal, Anus Disea. Survival outcomes used to generate version 9 American Joint Committee on Cancer staging system for anal cancer. CA Cancer J Clin. 2023 Sep-Oct; 73(5):516-523.
PMID: 37114458.
-
Hernandez S, Das P, Holliday EB, Shen L, Lu W, Johnson B, Messick CA, Taniguchi CM, Skibber J, Ludmir EB, You YN, Smith GL, Bednarski B, Kostousov L, Koay EJ, Minsky BD, Tillman M, Portier S, Eng C, Koong AC, Chang GJ, Foo WC, Wang J, Soto LS, Morris VK. Differential Spatial Gene and Protein Expression Associated with Recurrence Following Chemoradiation for Localized Anal Squamous Cell Cancer. Cancers (Basel). 2023 Mar 10; 15(6).
PMID: 36980587; PMCID: PMC10046657.
Citations:
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Jimeno A, Baranda J, Iams WT, Park JC, Mita M, Gordon MS, Taylor M, Dhani N, Leal AD, Neupane P, Eng C, Yeku O, Mita A, Moser JC, Butler M, Loughhead SM, Jennings J, Miselis NR, Ji RR, Nair N, Kornacker M, Zwirtes RF, Bernstein H, Sharei A. Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors. Invest New Drugs. 2023 04; 41(2):284-295.
PMID: 36867316; PMCID: PMC10140074.
Citations: Fields:
Translation:
HumansCellsCTClinical Trials
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Holowatyj AN, Wen W, Gibbs T, Seagle HM, Keller SR, Edwards DRV, Washington MK, Eng C, Perea J, Zheng W, Guo X. Racial/Ethnic and Sex Differences in Somatic Cancer Gene Mutations among Patients with Early-Onset Colorectal Cancer. Cancer Discov. 2023 03 01; 13(3):570-579.
PMID: 36520636; PMCID: PMC10436779.
Citations:
1 Fields:
Translation:
Humans
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Ciombor KK, Eng C. Immunotherapy in Localized Microsatellite Instability-High/Mismatch Repair Deficient Solid Tumors: Are We Ready for a New Standard of Care? J Clin Oncol. 2023 04 20; 41(12):2138-2140.
PMID: 36623236.
Citations:
1 Fields:
Translation:
HumansCells
-
Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Sepp?l? TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A, Guillem JG, Houwen BBSL, Kahi C, Kalady MF, Kastrinos F, K?hn F, Laghi L, Latchford A, Liska D, Lynch P, Malesci A, Mauri G, Meldolesi E, M?ller P, Monahan KJ, M?slein G, Murphy CC, Nass K, Ng K, Oliani C, Papaleo E, Patel SG, Puzzono M, Remo A, Ricciardiello L, Ripamonti CI, Siena S, Singh SK, Stadler ZK, Stanich PP, Syngal S, Turi S, Urso ED, Valle L, Vanni VS, Vilar E, Vitellaro M, You YN, Yurgelun MB, Zuppardo RA, Stoffel EM, Associazione Italiana Familiarit? Ereditariet? Tumori, Collaborative Group of the Americas on Inherited Gastrointestinal Cancer, European Hereditary Tumour Group, and the International Society for Gastrointestinal Hereditary Tumo. Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines. Clin Gastroenterol Hepatol. 2023 03; 21(3):581-603.e33.
PMID: 36549470; PMCID: PMC11207185.
Citations:
6 Fields:
Translation:
Humans
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Gunther JR, Chadha AS, Guha S, Raju GS, Maru DM, Munsell MF, Jiang Y, Yang P, Felix E, Clemons M, Mathew GG, Singh PK, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Eng C, Delclos ME, Crane CH, Das P, Krishnan S. A phase II randomized double blinded trial evaluating the efficacy of curcumin with pre-operative chemoradiation for rectal cancer. J Gastrointest Oncol. 2022 Dec; 13(6):2938-2950.
PMID: 36636059; PMCID: PMC9830363.
-
Lopez G, Eng C, Overman M, Ramirez D, Liu W, Beinhorn C, Sumler P, Prinsloo S, Li Y, Chen M, Bruera E, Cohen L. A randomized pilot study of oncology massage to treat chemotherapy-induced peripheral neuropathy. Sci Rep. 2022 11 08; 12(1):19023.
PMID: 36348045; PMCID: PMC9643426.
Citations:
1 Fields:
Translation:
Humans
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Morris VK, Kennedy EB, Baxter NN, Benson AB, Cercek A, Cho M, Ciombor KK, Cremolini C, Davis A, Deming DA, Fakih MG, Gholami S, Hong TS, Jaiyesimi I, Klute K, Lieu C, Sanoff H, Strickler JH, White S, Willis JA, Eng C. Treatment of Metastatic Colorectal Cancer: ASCO Guideline. J Clin Oncol. 2023 01 20; 41(3):678-700.
PMID: 36252154; PMCID: PMC10506310.
Citations:
30 Fields:
Translation:
Humans
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J?come AA, Peixoto RD, Gil MV, Ominelli J, Prolla G, Dienstmann R, Eng C. Biologics in rectal cancer. Expert Opin Biol Ther. 2022 10; 22(10):1245-1257.
PMID: 35912589.
Citations:
-
Johnson B, Haymaker CL, Parra ER, Soto LMS, Wang X, Thomas JV, Dasari A, Morris VK, Raghav K, Vilar E, Kee BK, Eng C, Parseghian CM, Wolff RA, Lee Y, Lorenzini D, Laberiano-Fernandez C, Verma A, Lang W, Wistuba II, Futreal A, Kopetz S, Overman MJ. Phase II study of durvalumab (anti-PD-L1) and trametinib (MEKi) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC). J Immunother Cancer. 2022 08; 10(8).
PMID: 36007963; PMCID: PMC9422817.
Citations:
-
LaPelusa M, Shen C, Gillaspie EA, Cann C, Lambright E, Chakravarthy AB, Gibson MK, Eng C. Variation in Treatment Patterns of Patients with Early-Onset Gastric Cancer. Cancers (Basel). 2022 Jul 26; 14(15).
PMID: 35892891; PMCID: PMC9332417.
Citations:
-
Goldberg RM, Adams R, Buyse M, Eng C, Grothey A, Sobrero AF, Lichtman SM, Benson AB, Punt CJA, Maughan T, Burzykowski T, Sommeijer D, Saad ED, Shi Q, Coart E, Koopman M, Schmoll HJ, Yoshino T, Taieb J, Tebbutt NC, Zalcberg J, Tabernero J, Van Cutsem E, Matheson A, Andr? T, Chibaudel B, de Gramont A. Clinical Trial Endpoints in Metastatic Cancer: Using Individual Participant Data to Inform Future Trials Methodology. J Natl Cancer Inst. 2022 06 13; 114(6):819-828.
PMID: 34865086; PMCID: PMC9194619.
Citations: Fields:
Translation:
Humans
-
Morris VK, Eng C, J?come AA. The Role of Immunotherapy in the Treatment of Anal Cancer and Future Strategies. Curr Treat Options Oncol. 2022 08; 23(8):1073-1085.
PMID: 35666353.
-
Eng C, Ciombor KK, Cho M, Dorth JA, Rajdev LN, Horowitz DP, Gollub MJ, Lockney NA, Muldoon RL, Washington MK, O'Brian BA, Benny A, Lebeck Lee CM, Benson AB, Goodman KA, Morris VK, J?come AA. Anal Cancer: Emerging Standards in a Rare Disease. J Clin Oncol. 2022 08 20; 40(24):2774-2788.
PMID: 35649196.
-
Eng C, Holowatyj AN. Colorectal Cancer Genomics by Genetic Ancestry. Cancer Discov. 2022 05 02; 12(5):1187-1188.
PMID: 35491647.
Citations: Fields:
Translation:
Humans
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Lin D, El Alam MB, Jaoude JA, Kouzy R, Phan JL, Elnaggar JH, Resendiz B, Medrano AYD, Lynn EJ, Nguyen ND, Noticewala SS, Mathew GG, Holliday EB, Minsky BD, Das P, Morris VK, Eng C, Mezzari MP, Petrosino JF, Ajami NJ, Klopp AH, Taniguchi CM, Colbert LE. Microbiome Dynamics During Chemoradiation Therapy for Anal Cancer. Int J Radiat Oncol Biol Phys. 2022 08 01; 113(5):974-984.
PMID: 35513187.
Citations: Fields:
Translation:
Humans
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Shen C, Tannenbaum D, Horn R, Rogers J, Eng C, Zhou S, Johnson B, Kopetz S, Morris V, Overman M, Parseghian C, Chang GJ, Lopez-Olivo MA, Kanwal R, Ellis LM, Dasari A. Overall Survival in Phase 3 Clinical Trials and the Surveillance, Epidemiology, and End Results Database in Patients With Metastatic Colorectal Cancer, 1986-2016: A Systematic Review. JAMA Netw Open. 2022 05 02; 5(5):e2213588.
PMID: 35608860; PMCID: PMC9131746.
Citations: Fields:
Translation:
Humans
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Morris V, Kee B, Overman M, Dasari A, Raghav K, Johnson B, Parseghian C, Wolff RA, Garg N, Eng C, Kopetz S. Clinical and pathologic features correlated with rare favorable survival in patients with BRAFV600E mutated colorectal cancer. J Gastrointest Oncol. 2022 Apr; 13(2):647-656.
PMID: 35557581; PMCID: PMC9086049.
Citations:
-
Lebeck Lee CM, Ziogas IA, Agarwal R, Alexopoulos SP, Ciombor KK, Matsuoka LK, Brown DB, Eng C. A contemporary systematic review on liver transplantation for unresectable liver metastases of colorectal cancer. Cancer. 2022 06 15; 128(12):2243-2257.
PMID: 35285949; PMCID: PMC9311758.
Citations: Fields:
Translation:
Humans
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Peterson SK, Basen-Engquist K, Demark-Wahnefried W, Prokhorov AV, Shinn EH, Martch SL, Beadle BM, Garden AS, Farcas E, Brandon Gunn G, Fuller CD, Morrison WH, Rosenthal DI, Phan J, Eng C, Cinciripini PM, Karam-Hage MA, Camero Garcia M, Patrick K. Feasibility of Mobile and Sensor Technology for Remote Monitoring in Cancer Care and Prevention. AMIA Annu Symp Proc. 2021; 2021:979-988.
PMID: 35308916; PMCID: PMC8861680.
Citations: Fields:
Translation:
Humans
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Holliday EB, Morris VK, Johnson B, Eng C, Ludmir EB, Das P, Minsky BD, Taniguchi C, Smith GL, Koay EJ, Koong AC, Delclos ME, Skibber JM, Rodriguez-Bigas MA, You YN, Bednarski BK, Tillman MM, Chang GJ, Jennings K, Messick CA. Definitive Intensity-Modulated Chemoradiation for Anal Squamous Cell Carcinoma: Outcomes and Toxicity of 428 Patients Treated at a Single Institution. Oncologist. 2022 02 03; 27(1):40-47.
PMID: 35305097; PMCID: PMC8842324.
Citations: Fields:
Translation:
Humans
-
Eng C, Agarwal R, Hayat MH, Byndloss MX, Holowatyj AN, Bailey C, Lieu CH, J?come AA. A comprehensive framework for early-onset colorectal cancer research. Lancet Oncol. 2022 03; 23(3):e116-e128.
PMID: 35090673.
Citations:
2 Fields:
Translation:
Humans
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Miranda KW, Cimino SK, Eng C. Targeted Fibroblast Growth Factor Receptor (FGFR) Inhibition in Recurrent, Metastatic Anal Carcinoma: A Case Report. Clin Colorectal Cancer. 2022 09; 21(3):272-275.
PMID: 35125320.
-
LaPelusa M, Shen C, Arhin ND, Cardin D, Tan M, Idrees K, Geevarghese S, Chakravarthy B, Berlin J, Eng C. Trends in the Incidence and Treatment of Early-Onset Pancreatic Cancer. Cancers (Basel). 2022 Jan 07; 14(2).
PMID: 35053447; PMCID: PMC8773833.
-
Tchelebi LT, Eng C, Messick CA, Hong TS, Ludmir EB, Kachnic LA, Zaorsky NG. Current treatment and future directions in the management of anal cancer. CA Cancer J Clin. 2022 03; 72(2):183-195.
PMID: 34847242.
Citations:
1 Fields:
Translation:
Humans
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Eng C, Hochster H. Early-Onset Colorectal Cancer: The Mystery Remains. J Natl Cancer Inst. 2021 11 29; 113(12):1608-1610.
PMID: 34405226; PMCID: PMC8634513.
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Lebeck Lee C, Zwerner J, O'Brian B, Eng C. Cutaneous Lymphangitic Carcinomatosis as the First Sign of Recurrent Malignancy in a Patient With a History of Rectal Adenocarcinoma. Clin Colorectal Cancer. 2021 12; 20(4):368-371.
PMID: 34690067.
Citations:
1 Fields:
Translation:
Humans
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Holowatyj AN, Eng C, Lewis MA. Incorporating Reproductive Health in the Clinical Management of Early-Onset Colorectal Cancer. JCO Oncol Pract. 2022 03; 18(3):169-172.
PMID: 34554830; PMCID: PMC8932489.
Citations:
1 Fields:
Translation:
Humans
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Rogers JE, Woodard TL, Gonzalez GM, Dasari A, Johnson B, Morris VK, Kee B, Vilar E, Nancy You Y, Chang GJ, Bednarski B, Skibber JM, Rodriguez-Bigas MA, Eng C. Colorectal cancer during pregnancy or postpartum: Case series and literature review. Obstet Med. 2022 Jun; 15(2):118-124.
PMID: 35845232; PMCID: PMC9277731.
Citations:
-
Cardin DB, Eng C. Pancreatic Cancer in Young Adults: Can Innovative Approaches Lead to Better Outcomes? J Natl Cancer Inst. 2021 09 04; 113(9):1125-1126.
PMID: 33755179; PMCID: PMC8418427.
Citations: Fields:
Translation:
Humans
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Arhin ND, Shen C, Bailey CE, Matsuoka LK, Hawkins AT, Holowatyj AN, Ciombor KK, Hopkins MB, Geiger TM, Kam AE, Roth MT, Lebeck Lee CM, Lapelusa M, Dasari A, Eng C. Surgical resection and survival outcomes in metastatic young adult colorectal cancer patients. Cancer Med. 2021 07; 10(13):4269-4281.
PMID: 34132476; PMCID: PMC8267130.
Citations: Fields:
Translation:
Humans
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Hubbard JM, Eng C, Cremolini C, Marshall JL. Considerations in the management of younger patients with colorectal cancer. Clin Adv Hematol Oncol. 2021 Jun; 19 Suppl 16(6):1-20.
PMID: 35289787.
Citations: Fields:
Translation:
Humans
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Eng C. Examining the increase in colorectal cancer in younger patients. Clin Adv Hematol Oncol. 2021 Jun; 19 Suppl 16(6):3-6.
PMID: 35289788.
Citations: Fields:
Translation:
Humans
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Hubbard JM, Eng C, Cremolini C, Marshall JL. Considerations in the management of younger patients With colorectal cancer: Q&A. Clin Adv Hematol Oncol. 2021 06; 19 Suppl 16(6):15-17.
PMID: 35289792.
Citations: Fields:
Translation:
Humans
-
Citations:
1 Fields:
Translation:
Humans
-
Hester R, Advani S, Rashid A, Holliday E, Messick C, Das P, You YN, Taniguchi C, Koay EJ, Bednarski B, Rodriguez-Bigas M, Skibber J, Wolff R, Chang GJ, Minsky BD, Foo WC, Rothschild N, Morris VK, Eng C. CEA as a blood-based biomarker in anal cancer. Oncotarget. 2021 May 25; 12(11):1037-1045.
PMID: 34084278; PMCID: PMC8169063.
-
Dasari A, Sobrero A, Yao J, Yoshino T, Schelman W, Yang Z, Chien C, Kania M, Tabernero J, Eng C. FRESCO-2: a global Phase III study investigating the efficacy and safety of fruquintinib in metastatic colorectal cancer. Future Oncol. 2021 Aug; 17(24):3151-3162.
PMID: 33993740.
Citations:
1 Fields:
Translation:
HumansCTClinical Trials
-
Livingston AJ, Bailey CE, Washington MK, Eng C. Squamous Cell Carcinoma of the Anal Verge with Sigmoid Colon Metastasis. Clin Colorectal Cancer. 2021 09; 20(3):e210-e213.
PMID: 34092493.
Citations: Fields:
Translation:
Humans
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Cohen AS, Grudzinski J, Smith GT, Peterson TE, Whisenant JG, Hickman TL, Ciombor KK, Cardin D, Eng C, Goff LW, Das S, Coffey RJ, Berlin JD, Manning HC. First-in-Human PET Imaging and Estimated Radiation Dosimetry of l-[5-11C]-Glutamine in Patients with Metastatic Colorectal Cancer. J Nucl Med. 2022 Jan; 63(1):36-43.
PMID: 33931465; PMCID: PMC8717201.
-
Cimino SK, Ciombor KK, Chakravarthy AB, Bailey CE, Hopkins MB, Geiger TM, Hawkins AT, Eng C. Safety considerations with new treatment regimens for anal cancer. Expert Opin Drug Saf. 2021 Aug; 20(8):889-902.
PMID: 33900857.
Citations:
2 Fields:
Translation:
Humans
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Gibbs T, Washington MK, Eng C, Idrees K, Davis J, Holowatyj AN. Histologic and Racial/Ethnic Patterns of Appendiceal Cancer among Young Patients. Cancer Epidemiol Biomarkers Prev. 2021 06; 30(6):1149-1155.
PMID: 33795212; PMCID: PMC8806661.
Citations: Fields:
Translation:
Humans
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Kam AE, Eng C. BRAF V600E mutated metastatic colorectal cancer: current progress and future directions. Expert Opin Biol Ther. 2021 10; 21(10):1311-1313.
PMID: 33761808.
Citations: Fields:
Translation:
Humans
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Eng C, Chen EY, Rogers J, Lewis M, Strosberg J, Thota R, Krishnamurthi S, Oberstein P, Govindarajan R, Buchschacher G, Patel S, Sohal D, Al-Toubah T, Philip P, Dasari A, Kennecke H, Stein S. Moving Beyond the Momentum: Innovative Approaches to Clinical Trial Implementation. JCO Oncol Pract. 2021 10; 17(10):607-614.
PMID: 33534616; PMCID: PMC8791825.
Citations:
4 Fields:
Translation:
HumansCells
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Eng C. BRAF Mutation in Colorectal Cancer: An Enigmatic Target. J Clin Oncol. 2021 02 01; 39(4):259-261.
PMID: 33503394.
Citations:
2 Fields:
Translation:
Humans
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Lenz HJ, Eng C, Scheithauer W, Middleton G, Chen W, Esser R, Nippgen J, Burris H, Sobrero A. Extended RAS Analysis of the Phase III EPIC Trial: Irinotecan + Cetuximab Versus Irinotecan as Second-Line Treatment for Patients with Metastatic Colorectal Cancer. Oncologist. 2021 02; 26(2):e261-e269.
PMID: 33191588; PMCID: PMC7873334.
Citations: Fields:
Translation:
HumansCTClinical Trials
-
Holowatyj AN, Eng C, Wen W, Idrees K, Guo X. Spectrum of Somatic Cancer Gene Variations Among Adults With Appendiceal Cancer by Age at Disease Onset. JAMA Netw Open. 2020 12 01; 3(12):e2028644.
PMID: 33295976; PMCID: PMC7726634.
Citations:
4 Fields:
Translation:
Humans
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Vreeland TJ, Johnson B, Kawaguchi Y, Wei SH, Nancy You Y, Vilar E, Vauthey JN, Eng C, J?come AA. The prognostic impact of RAS on overall survival following liver resection in early versus late-onset colorectal cancer patients. Br J Cancer. 2021 02; 124(4):797-804.
PMID: 33208919; PMCID: PMC7884678.
Citations:
1 Fields:
Translation:
Humans
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Roth MT, Eng C. Neoadjuvant Chemotherapy for Colon Cancer Cancers (Basel). 2020 09 26; 12(9).
PMID: 32825640; PMCID: PMC7564118.
Citations:
-
Rogers JE, Ohinata A, Wolff R, Morris VK, Johnson B, Mehdizadeh A, Rothschild ND, Ahmed SU, Guerra JL, Eng C, J?come AAA. Outcomes with anti-EGFR monoclonal antibodies in metastatic and recurrent anal squamous cell carcinoma. Expert Rev Anticancer Ther. 2020 10; 20(10):901-908.
PMID: 32799569.
Citations:
1 Fields:
Translation:
Humans
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Raghav K, Shen JP, Guerra JL, Scally CP, Taggart MW, Foo WC, Matamoros A, Shaw KR, Fournier K, Overman MJ, Eng C, J?come AA. Integrated clinico-molecular profiling of appendiceal adenocarcinoma reveals a unique grade-driven entity distinct from colorectal cancer. Br J Cancer. 2020 10; 123(8):1262-1270.
PMID: 32733093; PMCID: PMC7553941.
Citations:
1 Fields:
Translation:
Humans
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Noticewala SS, Ludmir EB, Eng C, Holliday EB, Minsky BD, Morris VK, Das P. Anal cancer treatment regimen considerations for the COVID-19 era: In regard to Tchelebi et al. Radiother Oncol. 2020 10; 151:56-57.
PMID: 32710989; PMCID: PMC7375313.
Citations:
1 Fields:
Translation:
HumansCellsPHPublic Health
-
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, Danso MA, Dennis K, Dupuis LL, Dusetzina SB, Eng C, Feyer PC, Jordan K, Noonan K, Sparacio D, Lyman GH. Antiemetics: ASCO Guideline Update. J Clin Oncol. 2020 08 20; 38(24):2782-2797.
PMID: 32658626.
Citations:
39 Fields:
Translation:
Humans
-
Coomes EA, Al-Shamsi HO, Meyers BM, Alhazzani W, Alhuraiji A, Chemaly RF, Almuhanna M, Wolff RA, Ibrahim NK, Chua MLK, Hotte SJ, Elfiki T, Curigliano G, Eng C, Grothey A, Xie C. Evolution of Cancer Care in Response to the COVID-19 Pandemic. Oncologist. 2020 09; 25(9):e1426-e1427.
PMID: 32536024; PMCID: PMC7323244.
Citations:
3 Fields:
Translation:
HumansCellsPHPublic Health
-
Dasari A, Morris VK, Allegra CJ, Atreya C, Benson AB, Boland P, Chung K, Copur MS, Corcoran RB, Deming DA, Dwyer A, Diehn M, Eng C, George TJ, Gollub MJ, Goodwin RA, Hamilton SR, Hechtman JF, Hochster H, Hong TS, Innocenti F, Iqbal A, Jacobs SA, Kennecke HF, Lee JJ, Lieu CH, Lenz HJ, Lindwasser OW, Odisio B, Ou FS, Porter L, Raghav K, Schrag D, Scott AJ, Shi Q, Strickler JH, Venook A, Yaeger R, Yothers G, You YN, Zell JA, Kopetz S, Montagut C. ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper. Nat Rev Clin Oncol. 2020 12; 17(12):757-770.
PMID: 32632268; PMCID: PMC7790747.
Citations:
60 Fields:
Translation:
Humans
-
Demisse R, Damle N, Kim E, Gong J, Fakih M, Eng C, Oesterich L, McKenny M, Ji J, Liu J, Louie R, Tam K, Gholami S, Halabi W, Monjazeb A, Dayyani F, Cho M. Neoadjuvant Immunotherapy-Based Systemic Treatment in MMR-Deficient or MSI-High Rectal Cancer: Case Series. J Natl Compr Canc Netw. 2020 07; 18(7):798-804.
PMID: 32634770.
Citations:
10 Fields:
Translation:
Humans
-
Lou E, Beg MS, Bergsland E, Eng C, Khorana AA, Kopetz S, Lubner S, Saltz L, Shankaran V, Zafar SY. Reply to S. Boutayeb et al. JCO Oncol Pract. 2020 08; 16(8):525.
PMID: 32574129.
Citations:
1 Fields:
Translation:
HumansCells
-
Holowatyj AN, Washington KM, Salaria SN, Lieu CH, Idrees K, Eng C. Early-Onset Appendiceal Cancer Survival by Race or Ethnicity in the United States. Gastroenterology. 2020 10; 159(4):1605-1608.
PMID: 32540351; PMCID: PMC9996638.
Citations:
3 Fields:
Translation:
Humans
-
Rao S, Sclafani F, Eng C, Adams RA, Guren MG, Sebag-Montefiore D, Benson A, Bryant A, Peckitt C, Segelov E, Roy A, Seymour MT, Welch J, Saunders MP, Muirhead R, O'Dwyer P, Bridgewater J, Bhide S, Glynne-Jones R, Arnold D, Cunningham D. International Rare Cancers Initiative Multicenter Randomized Phase II Trial of Cisplatin and Fluorouracil Versus Carboplatin and Paclitaxel in Advanced Anal Cancer: InterAAct. J Clin Oncol. 2020 08 01; 38(22):2510-2518.
PMID: 32530769; PMCID: PMC7406334.
Citations:
19 Fields:
Translation:
HumansCTClinical Trials
-
Ohinata A, Mahvash A, Overman MJ, Kee B, Fogelman D, Morris VK, Johnson B, Rothschild ND, Wolff RA, Eng C, J?come AA. Bevacizumab Does Not Influence the Efficacy of Partial Splenic Embolization in the Management of Chemotherapy-Induced Hypersplenism. Clin Colorectal Cancer. 2020 12; 19(4):e189-e199.
PMID: 32680816.
Citations: Fields:
Translation:
Humans
-
Kee B, Fogelman D, Dasari A, Shureiqi I, Raghav K, Morris V, Johnson B, Overman M, Wolff R, Kopetz S, Rogers J, Ahmed SU, Mehdizadeh A, Rothschild N, Eng C, J?come AA. FOLFOXIRI Versus Doublet Regimens in Right-Sided Metastatic Colorectal Cancer: Focus on Subsequent Therapies and Impact on Overall Survival. Clin Colorectal Cancer. 2020 12; 19(4):248-255.e6.
PMID: 32665092.
Citations: Fields:
Translation:
Humans
-
Coomes EA, Al-Shamsi HO, Meyers BM, Alhazzani W, Alhuraiji A, Chemaly RF, Almuhanna M, Wolff RA, Ibrahim NK, Chua MLK, Hotte SJ, Elfiki T, Curigliano G, Eng C, Grothey A, Xie C. In Reply. Oncologist. 2020 08; 25(8):e1252-e1253.
PMID: 32378772; PMCID: PMC7267302.
Citations: Fields:
Translation:
HumansCellsPHPublic Health
-
Ajani JA, Javle M, Eng C, Fogelman D, Smith J, Anderson B, Zhang C, Iizuka K. Phase I study of DFP-11207, a novel oral fluoropyrimidine with reasonable AUC and low Cmax and improved tolerability, in patients with solid tumors. Invest New Drugs. 2020 12; 38(6):1763-1773.
PMID: 32377978; PMCID: PMC7575509.
Citations:
1 Fields:
Translation:
HumansCTClinical Trials
-
Lou E, Beg S, Bergsland E, Eng C, Khorana A, Kopetz S, Lubner S, Saltz L, Shankaran V, Zafar SY. Modifying Practices in GI Oncology in the Face of COVID-19: Recommendations From Expert Oncologists on Minimizing Patient Risk. JCO Oncol Pract. 2020 07; 16(7):383-388.
PMID: 32352884.
Citations:
11 Fields:
Translation:
HumansCellsPHPublic Health
-
Al-Shamsi HO, Alhazzani W, Alhuraiji A, Coomes EA, Chemaly RF, Almuhanna M, Wolff RA, Ibrahim NK, Chua MLK, Hotte SJ, Meyers BM, Elfiki T, Curigliano G, Eng C, Grothey A, Xie C. A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: An International Collaborative Group. Oncologist. 2020 06; 25(6):e936-e945.
PMID: 32243668; PMCID: PMC7288661.
Citations:
262 Fields:
Translation:
HumansCellsPHPublic Health
-
Eng C, Fakih M, Amin M, Morris V, Hochster HS, Boland PM, Uronis H. A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer. Oncotarget. 2020 Apr 14; 11(15):1334-1343.
PMID: 32341753; PMCID: PMC7170499.
-
Eng C. TAS-102 plus bevacizumab: a new standard for metastatic colorectal cancer? Lancet Oncol. 2020 03; 21(3):326-327.
PMID: 31999945.
Citations: Fields:
Translation:
Humans
-
Yennurajalingam S, Carmack C, Balachandran D, Eng C, Lim B, Delgado M, Guzman Gutierrez D, Raznahan M, Park M, Hess KR, Williams JL, Lu Z, Ochoa J, Bruera E. Sleep disturbance in patients with cancer: a feasibility study of multimodal therapy. BMJ Support Palliat Care. 2021 Jun; 11(2):170-179.
PMID: 31924662.
Citations:
1 Fields:
Translation:
Humans
-
Pairawan S, Hess KR, Janku F, Sanchez NS, Mills Shaw KR, Eng C, Damodaran S, Javle M, Kaseb AO, Hong DS, Subbiah V, Fu S, Fogelman DR, Raymond VM, Lanman RB, Meric-Bernstam F. Cell-free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer. Clin Cancer Res. 2020 04 15; 26(8):1924-1931.
PMID: 31852833; PMCID: PMC7771658.
Citations:
17 Fields:
Translation:
Humans
-
Eng C, J?come AA. Role of immune checkpoint inhibitors in the treatment of colorectal cancer: focus on nivolumab. Expert Opin Biol Ther. 2019 12; 19(12):1247-1263.
PMID: 31642347.
Citations:
17 Fields:
Translation:
Humans
-
Kahle MP, Bailey AM, Wathoo C, Balaji K, Demirhan ME, Yang D, Javle M, Kaseb A, Eng C, Subbiah V, Janku F, Raymond VM, Lanman RB, Mills Shaw KR, Meric-Bernstam F, S?nchez NS. Identification of Actionable Genomic Alterations Using Circulating Cell-Free DNA. JCO Precis Oncol. 2019; 3.
PMID: 32923868; PMCID: PMC7448805.
-
Rogers JE, Eng C. Pharmacotherapeutic considerations for elderly patients with colorectal cancer. Expert Opin Pharmacother. 2019 Dec; 20(17):2139-2160.
PMID: 31456458.
Citations:
1 Fields:
Translation:
Humans
-
Korphaisarn K, Morris V, Davis JS, Overman MJ, Fogelman DR, Kee BK, Dasari A, Raghav KPS, Shureiqi I, Trupti M, Wolff RA, Eng C, Menter DG, Hamilton S, Kopetz S. Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma. Br J Cancer. 2019 09; 121(6):505-510.
PMID: 31406299; PMCID: PMC6738104.
Citations:
9 Fields:
Translation:
HumansCellsCTClinical Trials
-
Johnson B, Loree JM, Jacome AA, Mendis S, Syed M, Morris Ii VK, Parseghian CM, Dasari A, Pant S, Raymond VM, Vilar E, Overman M, Kee B, Eng C, Raghav K, Kopetz S. Atypical, Non-V600 BRAF Mutations as a Potential Mechanism of Resistance to EGFR Inhibition in Metastatic Colorectal Cancer. JCO Precis Oncol. 2019; 3.
PMID: 32914034; PMCID: PMC7446507.
-
Johnson B, Eng C. More questions regarding HIPEC in colorectal carcinomatosis. Lancet Gastroenterol Hepatol. 2019 10; 4(10):744-745.
PMID: 31371229.
Citations:
2 Fields:
Translation:
Humans
-
Eng C, Das P, Chang GJ, Rodriguez-Bigas M, Skibber JM, Wolff RA, Qiao W, Xing Y, Sethi S, Ohinata A, Crane CH, J?come AA. A Phase II Study of Capecitabine/Oxaliplatin With Concurrent Radiotherapy in Locally Advanced Squamous Cell Carcinoma of the Anal Canal. Clin Colorectal Cancer. 2019 12; 18(4):301-306.
PMID: 31350201.
Citations:
1 Fields:
Translation:
HumansCTClinical Trials
-
Lieu CH, Golemis EA, Serebriiskii IG, Newberg J, Hemmerich A, Connelly C, Messersmith WA, Eng C, Eckhardt SG, Frampton G, Cooke M, Meyer JE. Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer. Clin Cancer Res. 2019 10 01; 25(19):5852-5858.
PMID: 31243121; PMCID: PMC6774873.
Citations:
37 Fields:
Translation:
Humans
-
Citations:
7 Fields:
Translation:
HumansCTClinical Trials
-
Eng C, Messick C, Glynne-Jones R. The Management and Prevention of Anal Squamous Cell Carcinoma. Am Soc Clin Oncol Educ Book. 2019 Jan; 39:216-225.
PMID: 31099616.
Citations:
1 Fields:
Translation:
Humans
-
Chun YS, Passot G, Yamashita S, Nusrat M, Katsonis P, Loree JM, Conrad C, Tzeng CD, Xiao L, Aloia TA, Eng C, Kopetz SE, Lichtarge O, Vauthey JN. Deleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal Liver Metastases. Ann Surg. 2019 05; 269(5):917-923.
PMID: 28767562; PMCID: PMC7462436.
Citations:
52 Fields:
Translation:
Humans
-
Eng C, Kim TW, Bendell J, Tebbutt NC, Di Bartolomeo M, Falcone A, Fakih M, Kozloff M, Segal NH, Sobrero A, Yan Y, Chang I, Uyei A, Roberts L, IMblaze370 Investigators, Argil?s G, Ciardiello F. Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial. Lancet Oncol. 2019 06; 20(6):849-861.
PMID: 31003911.
Citations:
128 Fields:
Translation:
HumansCTClinical Trials
-
Eng C, Rogers JE. Current synthetic pharmacotherapy for treatment-resistant colorectal cancer: when urgent action is required. Expert Opin Pharmacother. 2019 Apr; 20(5):523-534.
PMID: 30590946.
Citations:
1 Fields:
Translation:
Humans
-
Jacome AA, Eng C. Experimental and investigational drugs for the treatment of anal cancer. Expert Opin Investig Drugs. 2018 12; 27(12):941-950.
PMID: 30381968.
Citations:
1 Fields:
Translation:
Humans
-
Jensen G, Tao R, Eng C, Skibber JM, Rodriguez-Bigas M, Chang GJ, You YN, Bednarski BK, Minsky BD, Koay E, Taniguchi C, Krishnan S, Das P. Treatment of primary rectal adenocarcinoma after prior pelvic radiation: The role of hyperfractionated accelerated reirradiation. Adv Radiat Oncol. 2018 Oct-Dec; 3(4):595-600.
PMID: 30370360; PMCID: PMC6200883.
-
Goumard C, Nancy You Y, Okuno M, Kutlu O, Chen HC, Simoneau E, Vega EA, Chun YS, David Tzeng C, Eng C, Vauthey JN, Conrad C. Minimally invasive management of the entire treatment sequence in patients with stage IV colorectal cancer: a propensity-score weighting analysis. HPB (Oxford). 2018 12; 20(12):1150-1156.
PMID: 30005993.
Citations:
1 Fields:
Translation:
Humans
-
Morris VK, Eng C. Role of Immunotherapy in the Treatment of Squamous Cell Carcinoma of the Anal Canal. J Natl Compr Canc Netw. 2018 07; 16(7):903-908.
PMID: 30006430.
Citations:
3 Fields:
Translation:
HumansCells
-
Osborne EM, Eng C, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Nancy You YQ, Bednarski BK, Minsky BD, Delclos ME, Koay E, Krishnan S, Crane CH, Das P. Hyperfractionated Accelerated Reirradiation for Patients With Recurrent Anal Cancer Previously Treated With Definitive Chemoradiation. Am J Clin Oncol. 2018 07; 41(7):632-637.
PMID: 27755060.
Citations:
5 Fields:
Translation:
Humans
-
Goey KKH, Glimelius B, Adams RA, Arnold D, Berlin JD, de Gramont A, Eng C, Falcone A, Grothey A, Heinemann V, Hochster HS, Kaplan RS, Kopetz S, Labianca R, Lieu CH, Meropol NJ, Price TJ, Schilsky RL, Schmoll HJ, Shacham-Shmueli E, Shi Q, Sobrero AF, Souglakos J, Van Cutsem E, Zalcberg J, van Oijen MGH, Punt CJA, Koopman M, S?rbye H, Andr? T, Bodoky G, D?az-Rubio E. Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group. Eur J Cancer. 2018 09; 100:35-45.
PMID: 29936065.
Citations:
11 Fields:
Translation:
HumansCells
-
Holliday EB, Lester SC, Harmsen WS, Eng C, Haddock MG, Krishnan S, Das P, Hallemeier CL. Extended-Field Chemoradiation Therapy for Definitive Treatment of Anal Canal Squamous Cell Carcinoma Involving the Para-Aortic Lymph Nodes. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):102-108.
PMID: 29907489.
Citations:
3 Fields:
Translation:
Humans
-
Pande M, Joon A, Brewster AM, Chen WV, Hopper JL, Eng C, Shete S, Casey G, Schumacher F, Lin Y, Harrison TA, White E, Ahsan H, Andrulis IL, Whittemore AS, John EM, Ko Win A, Makalic E, Schmidt DF, Kapuscinski MK, Ochs-Balcom HM, Gallinger S, Jenkins MA, Newcomb PA, Lindor NM, Peters U, Amos CI, Lynch PM. Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies. PLoS One. 2018; 13(4):e0196245.
PMID: 29698419; PMCID: PMC5919670.
Citations:
1 Fields:
Translation:
Humans
-
Hong DS, Moore K, Patel M, Grant SC, Burris HA, William WN, Jones S, Meric-Bernstam F, Infante J, Golden L, Zhang W, Martinez R, Wijayawardana S, Beckmann R, Lin AB, Eng C, Bendell J. Evaluation of Prexasertib, a Checkpoint Kinase 1 Inhibitor, in a Phase Ib Study of Patients with Squamous Cell Carcinoma. Clin Cancer Res. 2018 07 15; 24(14):3263-3272.
PMID: 29643063; PMCID: PMC6050086.
Citations:
28 Fields:
Translation:
HumansCTClinical Trials
-
Hwang JP, Lok AS, Fisch MJ, Cantor SB, Barbo A, Lin HY, Foreman JT, Vierling JM, Torres HA, Granwehr BP, Miller E, Eng C, Simon GR, Ahmed S, Ferrajoli A, Romaguera J, Suarez-Almazor ME. Models to Predict Hepatitis B Virus Infection Among Patients With Cancer Undergoing Systemic Anticancer Therapy: A Prospective Cohort Study. J Clin Oncol. 2018 Apr 01; 36(10):959-967.
PMID: 29447061; PMCID: PMC7351320.
-
Prinsloo S, Novy D, Driver L, Lyle R, Ramondetta L, Eng C, Lopez G, Li Y, Cohen L. The Long-Term Impact of Neurofeedback on Symptom Burden and Interference in Patients With Chronic Chemotherapy-Induced Neuropathy: Analysis of a Randomized Controlled Trial. J Pain Symptom Manage. 2018 05; 55(5):1276-1285.
PMID: 29421164.
Citations:
11 Fields:
Translation:
Humans
-
Ahmed S, Eng C. Role of Chemotherapy in the Neoadjuvant/Adjuvant Setting for Patients With Rectal Adenocarcinoma Undergoing Chemoradiotherapy and Surgery or Radiotherapy and Surgery. Curr Oncol Rep. 2018 01 23; 20(1):3.
PMID: 29362905.
Citations:
5 Fields:
Translation:
Humans
-
Johnson B, Eng C. The promise of immunotherapy in anal squamous cell carcinoma: a novel approach for an orphan disease. Clin Adv Hematol Oncol. 2017 Dec; 15(12):968-961.
PMID: 29315288.
Citations:
3 Fields:
Translation:
Humans
-
Holliday EB, Hunt A, You YN, Chang GJ, Skibber JM, Rodriguez-Bigas MA, Bednarski BK, Eng C, Koay EJ, Minsky BD, Taniguchi C, Krishnan S, Herman JM, Das P. Short course radiation as a component of definitive multidisciplinary treatment for select patients with metastatic rectal adenocarcinoma. J Gastrointest Oncol. 2017 Dec; 8(6):990-997.
PMID: 29299359; PMCID: PMC5750175.
-
Loree JM, Pereira AAL, Lam M, Willauer AN, Raghav K, Dasari A, Morris VK, Advani S, Menter DG, Eng C, Shaw K, Broaddus R, Routbort MJ, Liu Y, Morris JS, Luthra R, Meric-Bernstam F, Overman MJ, Maru D, Kopetz S. Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes. Clin Cancer Res. 2018 03 01; 24(5):1062-1072.
PMID: 29180604; PMCID: PMC5844818.
Citations:
80 Fields:
Translation:
Humans
-
Ahmed S, Eng C. Neoadjuvant Strategies: Locally Advanced Rectal Cancer. Clin Colon Rectal Surg. 2017 Nov; 30(5):383-386.
PMID: 29184474; PMCID: PMC5703667.
-
Brusco LL, Wathoo C, Mills Shaw KR, Holla VR, Bailey AM, Johnson AM, Khotskaya YB, Litzenburger BC, Sanchez NS, Zeng J, Bernstam EV, Eng C, Kee BK, Amaria RN, Routbort MJ, Mills GB, Mendelsohn J, Meric-Bernstam F. Physician interpretation of genomic test results and treatment selection. Cancer. 2018 03 01; 124(5):966-972.
PMID: 29165790; PMCID: PMC5821595.
Citations:
4 Fields:
Translation:
Humans
-
Mazard T, Boonsirikamchai P, Overman MJ, Asran MA, Choi H, Herron D, Eng C, Maru DM, Ychou M, Vauthey JN, Loyer EM, Kopetz S. Comparison of early radiological predictors of outcome in patients with colorectal cancer with unresectable hepatic metastases treated with bevacizumab. Gut. 2018 06; 67(6):1095-1102.
PMID: 29084828; PMCID: PMC10109500.
Citations:
8 Fields:
Translation:
Humans
-
Huang HJ, Hong DS, Tsimberidou AM, Fu S, Piha-Paul SA, Subbiah V, Karp DD, Naing A, Krug A, Enderle D, Priewasser T, Noerholm M, Eitan E, Coticchia C, Stoll G, Jordan LM, Eng C, Kopetz ES, Skog J, Meric-Bernstam F, Janku F, M?hrmann L. Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers. Clin Cancer Res. 2018 01 01; 24(1):181-188.
PMID: 29051321; PMCID: PMC5754253.
Citations:
63 Fields:
Translation:
HumansCells
-
Clarke CN, Lee MS, Wei W, Manyam G, Jiang ZQ, Lu Y, Morris J, Broom B, Menter D, Vilar-Sanchez E, Raghav K, Eng C, Chang GJ, Simon I, Bernards R, Overman M, Mills GB, Maru D, Kopetz S. Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival. Ann Surg Oncol. 2017 Dec; 24(13):4051-4058.
PMID: 28936799; PMCID: PMC6063735.
Citations:
14 Fields:
Translation:
Humans
-
Rogers JE, Eng C. Pharmacotherapy of Anal Cancer. Drugs. 2017 Sep; 77(14):1519-1530.
PMID: 28770514.
Citations:
3 Fields:
Translation:
Humans
-
Pereira AAL, Morelli MP, Overman M, Kee B, Fogelman D, Vilar E, Shureiqi I, Raghav K, Eng C, Manuel S, Crosby S, Wolff RA, Banks K, Lanman R, Talasaz A, Kopetz S, Morris V. Clinical utility of circulating cell-free DNA in advanced colorectal cancer. PLoS One. 2017; 12(8):e0183949.
PMID: 28850629; PMCID: PMC5574560.
Citations:
12 Fields:
Translation:
Humans
-
Sagebiel TL, Mohamed A, Matamoros A, Taggart MW, Doamekpor F, Raghav KP, Mann GN, Mansfield PF, Eng C, Royal RE, Foo WC, Ensor JE, Fournier KF, Overman MJ. Utility of Appendiceal Calcifications Detected on Computed Tomography as a Predictor for an Underlying Appendiceal Epithelial Neoplasm. Ann Surg Oncol. 2017 Nov; 24(12):3667-3672.
PMID: 28831698.
Citations:
5 Fields:
Translation:
Humans
-
Morris V, Rao X, Pickering C, Foo WC, Rashid A, Eterovic K, Kim T, Chen K, Wang J, Shaw K, Eng C. Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal. Mol Cancer Res. 2017 11; 15(11):1542-1550.
PMID: 28784613; PMCID: PMC5991496.
Citations:
22 Fields:
Translation:
HumansAnimals
-
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, Danso MA, Dennis K, Dupuis LL, Dusetzina SB, Eng C, Feyer PC, Jordan K, Noonan K, Sparacio D, Somerfield MR, Lyman GH. Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2017 Oct 01; 35(28):3240-3261.
PMID: 28759346.
Citations:
159 Fields:
Translation:
Humans
-
Grotz TE, Overman MJ, Eng C, Raghav KP, Royal RE, Mansfield PF, Mann GN, Robinson KA, Beaty KA, Rafeeq S, Matamoros A, Taggart MW, Fournier KF. Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Moderately and Poorly Differentiated Appendiceal Adenocarcinoma: Survival Outcomes and Patient Selection. Ann Surg Oncol. 2017 Sep; 24(9):2646-2654.
PMID: 28695394.
Citations:
8 Fields:
Translation:
Humans
-
Citations:
23 Fields:
Translation:
Humans
-
Long Y, Sanchez-Espiridion B, Lin M, White L, Mishra L, Raju GS, Kopetz S, Eng C, Hildebrandt MAT, Chang DW, Ye Y, Liang D, Wu X. Global and targeted serum metabolic profiling of colorectal cancer progression. Cancer. 2017 Oct 15; 123(20):4066-4074.
PMID: 28640361; PMCID: PMC5626581.
Citations:
26 Fields:
Translation:
Humans
-
Korphaisarn K, Morris VK, Overman MJ, Fogelman DR, Kee BK, Raghav KPS, Manuel S, Shureiqi I, Wolff RA, Eng C, Menter D, Hamilton SR, Kopetz S, Dasari A. FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma. Oncotarget. 2017 Jun 13; 8(24):39268-39279.
PMID: 28424412; PMCID: PMC5503612.
Citations:
32 Fields:
Translation:
Humans
-
You YN, Skibber JM, Rodriguez-Bigas MA, Das P, Eng C, Kopetz S, Wolff RA, Crane CH, Krishnan S, Minsky B, Hu CY, Nguyen S, Chang GJ, Park IJ. Oncologic and Functional Hazards of Obesity Among Patients With Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiation Therapy. Am J Clin Oncol. 2017 Jun; 40(3):277-282.
PMID: 27028350; PMCID: PMC5042800.
Citations:
5 Fields:
Translation:
Humans
-
Hwang JP, Suarez-Almazor ME, Cantor SB, Barbo A, Lin HY, Ahmed S, Chavez-MacGregor M, Donato-Santana C, Eng C, Ferrajoli A, Fisch MJ, McLaughlin P, Simon GR, Rondon G, Shpall EJ, Lok AS. Impact of the timing of hepatitis B virus identification and anti-hepatitis B virus therapy initiation on the risk of adverse liver outcomes for patients receiving cancer therapy. Cancer. 2017 Sep 01; 123(17):3367-3376.
PMID: 28518219; PMCID: PMC5568919.
Citations:
4 Fields:
Translation:
HumansCells
-
You YN, Shiozaki H, Lee JE, Passot G, Goumard C, Okuno M, Aloia TA, Eng C, Chang G, Vauthey JN, Conrad C. Total Laparoscopic Management for Stage IV Colorectal Cancer Requiring Multivisceral Resection. Ann Surg Oncol. 2017 Sep; 24(9):2595.
PMID: 28510798.
Citations: Fields:
Translation:
Humans
-
Uemura M, Qiao W, Fournier K, Morris J, Mansfield P, Eng C, Royal RE, Wolff RA, Raghav K, Mann GN, Overman MJ. Retrospective study of nonmucinous appendiceal adenocarcinomas: role of systemic chemotherapy and cytoreductive surgery. BMC Cancer. 2017 05 15; 17(1):331.
PMID: 28506255; PMCID: PMC5433007.
Citations:
4 Fields:
Translation:
Humans
-
Subbiah V, Khawaja MR, Hong DS, Amini B, Yungfang J, Liu H, Johnson A, Schrock AB, Ali SM, Sun JX, Fabrizio D, Piha-Paul S, Fu S, Tsimberidou AM, Naing A, Janku F, Karp DD, Overman M, Eng C, Kopetz S, Meric-Bernstam F, Falchook GS. First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients. JCI Insight. 2017 Apr 20; 2(8).
PMID: 28422758; PMCID: PMC5396533.
-
Gunther JR, Chadha AS, Shin US, Park IJ, Kattepogu KV, Grant JD, Weksberg DC, Eng C, Kopetz SE, Das P, Delclos ME, Kaur H, Maru DM, Skibber JM, Rodriguez-Bigas MA, You YN, Krishnan S, Chang GJ. Preoperative radiation dose escalation for rectal cancer using a concomitant boost strategy improves tumor downstaging without increasing toxicity: A matched-pair analysis. Adv Radiat Oncol. 2017 Jul-Sep; 2(3):455-464.
PMID: 29114614; PMCID: PMC5605486.
-
Citations:
7 Fields:
Translation:
Humans
-
Parseghian CM, Parikh NU, Wu JY, Jiang ZQ, Henderson L, Tian F, Raghav K, Dasari A, Fogelman DR, Katsiampoura AD, Menter DG, Wolff RA, Eng C, Overman MJ, Gallick GE, Kopetz S, Pastor B, Ychou M, Thierry AR. Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer. Clin Cancer Res. 2017 Aug 01; 23(15):4146-4154.
PMID: 28280091; PMCID: PMC5540760.
Citations:
26 Fields:
Translation:
HumansCTClinical Trials
-
Mehrvarz Sarshekeh A, Advani S, Overman MJ, Manyam G, Kee BK, Fogelman DR, Dasari A, Raghav K, Vilar E, Manuel S, Shureiqi I, Wolff RA, Patel KP, Luthra R, Shaw K, Eng C, Maru DM, Routbort MJ, Meric-Bernstam F, Kopetz S. Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer. PLoS One. 2017; 12(3):e0173345.
PMID: 28267766; PMCID: PMC5340382.
-
Zhao L, Chang DW, Gong Y, Eng C, Wu X. Measurement of DNA damage in peripheral blood by the ?-H2AX assay as predictor of colorectal cancer risk. DNA Repair (Amst). 2017 05; 53:24-30.
PMID: 28291710.
Citations:
5 Fields:
Translation:
HumansCells
-
Citations:
12 Fields:
Translation:
Humans
-
Morris VK, Salem ME, Nimeiri H, Iqbal S, Singh P, Ciombor K, Polite B, Deming D, Chan E, Wade JL, Xiao L, Bekaii-Saab T, Vence L, Blando J, Mahvash A, Foo WC, Ohaji C, Pasia M, Bland G, Ohinata A, Rogers J, Mehdizadeh A, Banks K, Lanman R, Wolff RA, Streicher H, Allison J, Sharma P, Eng C. Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study. Lancet Oncol. 2017 04; 18(4):446-453.
PMID: 28223062; PMCID: PMC5809128.
Citations:
120 Fields:
Translation:
HumansCTClinical Trials
-
Zuo X, Xu W, Xu M, Tian R, Moussalli MJ, Mao F, Zheng X, Wang J, Morris JS, Gagea M, Eng C, Kopetz S, Maru DM, Rashid A, Broaddus R, Wei D, Hung MC, Sood AK, Shureiqi I. Metastasis regulation by PPARD expression in cancer cells. JCI Insight. 2017 01 12; 2(1):e91419.
PMID: 28097239; PMCID: PMC5214933.
Citations:
34 Fields:
Translation:
HumansAnimalsCells
-
Tao R, Tsai CJ, Jensen G, Eng C, Kopetz S, Overman MJ, Skibber JM, Rodriguez-Bigas M, Chang GJ, You YN, Bednarski BK, Minsky BD, Delclos ME, Koay E, Krishnan S, Crane CH, Das P. Hyperfractionated accelerated reirradiation for rectal cancer: An analysis of outcomes and toxicity. Radiother Oncol. 2017 01; 122(1):146-151.
PMID: 28057329.
Citations:
16 Fields:
Translation:
Humans
-
Morris V, Eng C. Metastatic Anal Cancer and Novel Agents. Surg Oncol Clin N Am. 2017 01; 26(1):133-142.
PMID: 27889032.
Citations:
2 Fields:
Translation:
Humans
-
Yamashita S, Loyer E, Kang HC, Aloia TA, Chun YS, Mehran RJ, Eng C, Lee JE, Vauthey JN, Conrad C. Total Transthoracic Approach Facilitates Laparoscopic Hepatic Resection in Patients with Significant Prior Abdominal Surgery. Ann Surg Oncol. 2017 May; 24(5):1376-1377.
PMID: 27878479.
Citations:
5 Fields:
Translation:
Humans
-
Liu C, Eng C, Shen J, Lu Y, Takata Y, Mehdizadeh A, Chang GJ, Rodriguez-Bigas MA, Li Y, Chang P, Mao Y, Hassan MM, Wang F, Li D. Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer. Oncotarget. 2016 Nov 15; 7(46):76250-76260.
PMID: 27788488; PMCID: PMC5342811.
Citations:
42 Fields:
Translation:
HumansCells
-
Eng C. Preface. Surg Oncol Clin N Am. 2017 01; 26(1):xv-xvi.
PMID: 27889042.
Citations: Fields:
Translation:
Humans
-
Overman MJ, Morris V, Moinova H, Manyam G, Ensor J, Lee MS, Eng C, Kee B, Fogelman D, Shroff RT, LaFramboise T, Mazard T, Feng T, Hamilton S, Broom B, Lutterbaugh J, Issa JP, Markowitz SD, Kopetz S. Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin. Oncotarget. 2016 Oct 11; 7(41):67495-67506.
PMID: 27542211; PMCID: PMC5341892.
Citations:
18 Fields:
Translation:
HumansCellsCTClinical Trials
-
Morris V, Eng C. Summary of emerging targets in anal cancer: the case for an immunotherapy based-approach. J Gastrointest Oncol. 2016 Oct; 7(5):721-726.
PMID: 27747086; PMCID: PMC5056256.
-
Fournier K, Rafeeq S, Taggart M, Kanaby P, Ning J, Chen HC, Overman M, Raghav K, Eng C, Mansfield P, Royal R. Low-grade Appendiceal Mucinous Neoplasm of Uncertain Malignant Potential (LAMN-UMP): Prognostic Factors and Implications for Treatment and Follow-up. Ann Surg Oncol. 2017 Jan; 24(1):187-193.
PMID: 27660258.
Citations:
13 Fields:
Translation:
Humans
-
Rogers JE, Ohinata A, Silva NN, Mehdizadeh A, Eng C. Epidermal growth factor receptor inhibition in metastatic anal cancer. Anticancer Drugs. 2016 09; 27(8):804-8.
PMID: 27272412.
Citations:
9 Fields:
Translation:
Humans
-
Raghav K, Morris V, Tang C, Morelli P, Amin HM, Chen K, Manyam GC, Broom B, Overman MJ, Shaw K, Meric-Bernstam F, Maru D, Menter D, Ellis LM, Eng C, Hong D, Kopetz S. MET amplification in metastatic colorectal cancer: an acquired response to EGFR inhibition, not a de novo phenomenon. Oncotarget. 2016 08 23; 7(34):54627-54631.
PMID: 27421137; PMCID: PMC5342368.
Citations:
23 Fields:
Translation:
Humans
-
Eng C. POLE mutations in colorectal cancer: a new biomarker? Lancet Gastroenterol Hepatol. 2016 11; 1(3):176-177.
PMID: 28404085.
Citations:
5 Fields:
Translation:
Humans
-
Bailey HH, Chuang LT, duPont NC, Eng C, Foxhall LE, Merrill JK, Wollins DS, Blanke CD. American Society of Clinical Oncology Statement: Human Papillomavirus Vaccination for Cancer Prevention. J Clin Oncol. 2016 05 20; 34(15):1803-12.
PMID: 27069078.
Citations:
25 Fields:
Translation:
HumansPHPublic Health
-
Eng C, Bessudo A, Hart LL, Severtsev A, Gladkov O, Kopp MV, Vladimirov V, Langdon R, Kotiv B, Barni S, Hsu C, Bolotin E, von Roemeling R, Schwartz B, Bendell JC, M?ller L. A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy. Int J Cancer. 2016 Jul 01; 139(1):177-86.
PMID: 26891420; PMCID: PMC5071720.
Citations:
25 Fields:
Translation:
HumansCTClinical Trials
-
Rogers JE, Dasari A, Eng C. The Treatment of Colorectal Cancer During Pregnancy: Cytotoxic Chemotherapy and Targeted Therapy Challenges. Oncologist. 2016 05; 21(5):563-70.
PMID: 27000464; PMCID: PMC4861360.
Citations:
11 Fields:
Translation:
HumansAnimals
-
Citations:
11 Fields:
Translation:
Humans
-
Rogers JE, Silva NN, Eng C. Cetuximab in combination with cisplatin and 5-Fluorouracil induces dramatic response in metastatic refractory squamous cell carcinoma of the anal canal. J Gastrointest Oncol. 2015 Oct; 6(5):E82-5.
PMID: 26487956; PMCID: PMC4570906.
-
Citations:
11 Fields:
Translation:
HumansCells
-
Eng C. Circulating DNA biomarkers: a primer for metastatic colorectal cancer? Lancet Oncol. 2015 Aug; 16(8):878-9.
PMID: 26184521.
Citations:
1 Fields:
Translation:
Humans
-
Dawood S, Sirohi B, Shrikhande SV, Toh HC, Eng C. Potential Prognostic Impact of Baseline CEA Level and Surgery of Primary Tumor Among Patients with Synchronous Stage IV Colorectal Cancer: A Large Population Based Study. Indian J Surg Oncol. 2015 Sep; 6(3):198-206.
PMID: 27217664; PMCID: PMC4856686.
-
Citations:
58 Fields:
Translation:
HumansCTClinical Trials
-
Citations:
2 Fields:
Translation:
Humans
-
Choe JH, Overman MJ, Fournier KF, Royal RE, Ohinata A, Rafeeq S, Beaty K, Phillips JK, Wolff RA, Mansfield PF, Eng C. Improved Survival with Anti-VEGF Therapy in the Treatment of Unresectable Appendiceal Epithelial Neoplasms. Ann Surg Oncol. 2015 Aug; 22(8):2578-84.
PMID: 25582740.
Citations:
11 Fields:
Translation:
Humans
-
Eng C, Roach N, Longabaugh M, Fisher G. Perspectives on clinical trials for gastrointestinal malignancies. Am Soc Clin Oncol Educ Book. 2015; 40-3.
PMID: 25993140.
Citations: Fields:
Translation:
Humans
-
Bogaerts J, Sydes MR, Keat N, McConnell A, Benson A, Ho A, Roth A, Fortpied C, Eng C, Peckitt C, Coens C, Pettaway C, Arnold D, Hall E, Marshall E, Sclafani F, Hatcher H, Earl H, Paul J, Whelan J, Panageas K, Wheatley K, Harrington K, Licitra L, Billingham L, Hensley M, McCabe M, Patel PM, Carvajal R, Wilson R, Glynne-Jones R, McWilliams R, Leyvraz S, Rao S, Nicholson S, Filiaci V, Negrouk A, Lacombe D, Dupont E, Welch JJ, Law K, Trimble T, Seymour M, Ray-Coquard I, Blay JY, Pauport? I. Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative. Eur J Cancer. 2015 Feb; 51(3):271-81.
PMID: 25542058; PMCID: PMC4639696.
Citations:
40 Fields:
Translation:
Humans
-
Morris V, Overman MJ, Eng C, Garrett CR, Boutin AT, Ferrarotto R, Lee M, Jiang ZQ, Vauthey JN, Vilar E, Maru D, Kopetz S, Pereira AA, Rego JF, Hoff PM. Association between KRAS mutation and lung metastasis in advanced colorectal cancer. Br J Cancer. 2015 Feb 03; 112(3):424-8.
PMID: 25535726; PMCID: PMC4453646.
Citations:
40 Fields:
Translation:
Humans
-
Rogers JE, Eng C. Cetuximab in refractory squamous cell carcinoma of the anal canal. J Gastrointest Cancer. 2014 Dec; 45 Suppl 1:198-200.
PMID: 24908401.
Citations:
4 Fields:
Translation:
Humans
-
Eng C, Chang GJ, You YN, Das P, Rodriguez-Bigas M, Xing Y, Vauthey JN, Rogers JE, Ohinata A, Pathak P, Sethi S, Phillips JK, Crane CH, Wolff RA. The role of systemic chemotherapy and multidisciplinary management in improving the overall survival of patients with metastatic squamous cell carcinoma of the anal canal. Oncotarget. 2014 Nov 30; 5(22):11133-42.
PMID: 25373735; PMCID: PMC4294384.
Citations:
34 Fields:
Translation:
Humans
-
Abboud M, Eng C, Beddar AS, Krishnan S, Delclos ME, Crane CH, Das P, Mitchell MP. Intensity-modulated radiation therapy with concurrent chemotherapy for anal cancer: outcomes and toxicity. Am J Clin Oncol. 2014 Oct; 37(5):461-6.
PMID: 23466576.
Citations:
24 Fields:
Translation:
Humans
-
Lieu CH, Renfro LA, de Gramont A, Meyers JP, Maughan TS, Seymour MT, Saltz L, Goldberg RM, Sargent DJ, Eckhardt SG, Eng C, Aide et Recherche en Canc?rologie Digestive Foundation. Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD Clinical Trials Program. J Clin Oncol. 2014 Sep 20; 32(27):2975-84.
PMID: 25002720; PMCID: PMC4809210.
Citations:
53 Fields:
Translation:
Humans
-
Kosturakis AK, Eng C, Wendelschafer-Crabb G, Kennedy WR, Simone DA, Wang XS, Cleeland CS, Dougherty PM, de Carvalho Barbosa M. A quantitative sensory analysis of peripheral neuropathy in colorectal cancer and its exacerbation by oxaliplatin chemotherapy. Cancer Res. 2014 Nov 01; 74(21):5955-62.
PMID: 25183707; PMCID: PMC4216766.
Citations:
26 Fields:
Translation:
Humans
-
Ahmed S, Eng C. Optimal treatment strategies for anal cancer. Curr Treat Options Oncol. 2014 Sep; 15(3):443-55.
PMID: 25008956.
Citations:
1 Fields:
Translation:
Humans
-
Citations:
7 Fields:
Translation:
Humans
-
Morris VK, Lucas FAS, Overman MJ, Eng C, Morelli MP, Jiang ZQ, Luthra R, Meric-Bernstam F, Maru D, Scheet P, Kopetz S, Vilar E. Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer. Ann Oncol. 2014 Oct; 25(10):2008-2014.
PMID: 25009008; PMCID: PMC4176451.
Citations:
29 Fields:
Translation:
Humans
-
Eng C, Ahmed S. Optimal management of squamous cell carcinoma of the anal canal: where are we now? Expert Rev Anticancer Ther. 2014 Aug; 14(8):877-86.
PMID: 24981728.
Citations:
2 Fields:
Translation:
HumansPHPublic Health
-
Morris V, Overman MJ, Jiang ZQ, Garrett C, Agarwal S, Eng C, Kee B, Fogelman D, Dasari A, Wolff R, Maru D, Kopetz S. Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer. Clin Colorectal Cancer. 2014 Sep; 13(3):164-71.
PMID: 25069797; PMCID: PMC4266576.
Citations:
48 Fields:
Translation:
Humans
-
Van Cutsem E, Eng C, Nowara E, Swieboda-Sadlej A, Tebbutt NC, Mitchell E, Davidenko I, Stephenson J, Prenen H, Deng H, Tang R, McCaffery I, Oliner KS, Chen L, Gansert J, Loh E, Smethurst D, Elez E, Tabernero J. Randomized phase Ib/II trial of rilotumumab or ganitumab with panitumumab versus panitumumab alone in patients with wild-type KRAS metastatic colorectal cancer. Clin Cancer Res. 2014 Aug 15; 20(16):4240-50.
PMID: 24919569; PMCID: PMC4371780.
Citations:
50 Fields:
Translation:
HumansCTClinical Trials
-
Law L, Rogers J, Eng C. Delayed Presentation of DPD Deficiency in Colorectal Cancer. J Adv Pract Oncol. 2014 May; 5(3):205-10.
PMID: 25089219; PMCID: PMC4114495.
-
Rogers JE, Crane CH, Das P, Delclos M, Gould MS, Ohinata A, Malatek D, Eng C. Definitive chemoradiation in oligometastatic squamous cell carcinoma of the anal canal. Gastrointest Cancer Res. 2014 Mar; 7(2):65-8.
PMID: 24799976; PMCID: PMC4007681.
-
Haynes AB, You YN, Hu CY, Eng C, Kopetz ES, Rodriguez-Bigas MA, Skibber JM, Cantor SB, Chang GJ. Postoperative chemotherapy use after neoadjuvant chemoradiotherapy for rectal cancer: Analysis of Surveillance, Epidemiology, and End Results-Medicare data, 1998-2007. Cancer. 2014 Apr 15; 120(8):1162-70.
PMID: 24474245; PMCID: PMC3981916.
Citations:
15 Fields:
Translation:
Humans
-
Blackham AU, Swett K, Eng C, Sirintrapun J, Bergman S, Geisinger KR, Votanopoulos K, Stewart JH, Shen P, Levine EA. Perioperative systemic chemotherapy for appendiceal mucinous carcinoma peritonei treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. J Surg Oncol. 2014 Jun; 109(7):740-5.
PMID: 24375188; PMCID: PMC4010799.
Citations:
17 Fields:
Translation:
Humans
-
Guo Y, Jones D, Palmer JL, Forman A, Dakhil SR, Velasco MR, Weiss M, Gilman P, Mills GM, Noga SJ, Eng C, Overman MJ, Fisch MJ. Oral alpha-lipoic acid to prevent chemotherapy-induced peripheral neuropathy: a randomized, double-blind, placebo-controlled trial. Support Care Cancer. 2014 May; 22(5):1223-31.
PMID: 24362907; PMCID: PMC5924730.
Citations:
41 Fields:
Translation:
Humans
-
Das P, Eng C, Rodriguez-Bigas MA, Chang GJ, Skibber JM, You YN, Maru DM, Munsell MF, Clemons MV, Kopetz SE, Garrett CR, Shureiqi I, Delclos ME, Krishnan S, Crane CH. Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial. Int J Radiat Oncol Biol Phys. 2014 Feb 01; 88(2):301-5.
PMID: 24315563; PMCID: PMC5592790.
Citations:
8 Fields:
Translation:
HumansCTClinical Trials
-
Rogers JE, Ohinata A, Dasari A, Eng C. Atypical metastatic presentations in colorectal cancer: a case series. Clin Colorectal Cancer. 2014 Mar; 13(1):e1-4.
PMID: 24342822.
Citations:
3 Fields:
Translation:
Humans
-
Raghav KP, Shetty AV, Kazmi SM, Zhang N, Morris J, Taggart M, Fournier K, Royal R, Mansfield P, Eng C, Wolff RA, Overman MJ. Impact of molecular alterations and targeted therapy in appendiceal adenocarcinomas. Oncologist. 2013; 18(12):1270-7.
PMID: 24149137; PMCID: PMC3868421.
Citations:
18 Fields:
Translation:
HumansCTClinical Trials
-
Lieu CH, Tran H, Jiang ZQ, Mao M, Overman MJ, Lin E, Eng C, Morris J, Ellis L, Heymach JV, Kopetz S. The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer. PLoS One. 2013; 8(10):e77117.
PMID: 24143206; PMCID: PMC3797099.
Citations:
55 Fields:
Translation:
HumansCTClinical Trials
-
Agarwal A, Chang GJ, Hu CY, Taggart M, Rashid A, Park IJ, You YN, Das P, Krishnan S, Crane CH, Rodriguez-Bigas M, Skibber J, Ellis L, Eng C, Kopetz S, Maru DM. Quantified pathologic response assessed as residual tumor burden is a predictor of recurrence-free survival in patients with rectal cancer who undergo resection after neoadjuvant chemoradiotherapy. Cancer. 2013 Dec 15; 119(24):4231-41.
PMID: 24089344; PMCID: PMC5897128.
Citations:
21 Fields:
Translation:
Humans
-
Eng C, Chang GJ, You YN, Das P, Xing Y, Delclos M, Wolff RA, Rodriguez-Bigas MA, Skibber J, Ohinata A, Gould S, Phillips J, Crane CH. Long-term results of weekly/daily cisplatin-based chemoradiation for locally advanced squamous cell carcinoma of the anal canal. Cancer. 2013 Nov 01; 119(21):3769-75.
PMID: 24037775.
Citations:
12 Fields:
Translation:
Humans
-
Citations:
24 Fields:
Translation:
Humans
-
Eng C. Will PICCOLO affect metastatic colorectal cancer therapy? Lancet Oncol. 2013 Jul; 14(8):679-80.
PMID: 23725852.
Citations: Fields:
Translation:
Humans
-
Skinner HD, Crane CH, Garrett CR, Eng C, Chang GJ, Skibber JM, Rodriguez-Bigas MA, Kelly P, Sandulache VC, Delclos ME, Krishnan S, Das P. Metformin use and improved response to therapy in rectal cancer. Cancer Med. 2013 Feb; 2(1):99-107.
PMID: 24133632; PMCID: PMC3797563.
Citations:
41 Fields:
Translation:
Humans
-
Liu SV, Lenkiewicz E, Evers L, Holley T, Kiefer J, Ruiz C, Glatz K, Bubendorf L, Demeure MJ, Eng C, Ramanathan RK, Von Hoff DD, Barrett MT. Genomic analysis and selected molecular pathways in rare cancers. Phys Biol. 2012 Dec; 9(6):065004.
PMID: 23196986.
Citations:
3 Fields:
Translation:
Humans
-
Citations:
1 Fields:
Translation:
Humans
-
Kim DD, Eng C. The promise of mTOR inhibitors in the treatment of colorectal cancer. Expert Opin Investig Drugs. 2012 Dec; 21(12):1775-88.
PMID: 22978346.
Citations:
15 Fields:
Translation:
HumansAnimals
-
Lin M, Eng C, Hawk ET, Huang M, Lin J, Gu J, Ellis LM, Wu X. Identification of polymorphisms in ultraconserved elements associated with clinical outcomes in locally advanced colorectal adenocarcinoma. Cancer. 2012 Dec 15; 118(24):6188-98.
PMID: 22673945; PMCID: PMC3465518.
Citations:
9 Fields:
Translation:
HumansAnimalsCells
-
Lin M, Gu J, Eng C, Ellis LM, Hildebrandt MA, Lin J, Huang M, Calin GA, Wang D, Dubois RN, Hawk ET, Wu X. Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients. Clin Cancer Res. 2012 Jul 15; 18(14):3982-91.
PMID: 22661538; PMCID: PMC4141857.
Citations:
35 Fields:
Translation:
Humans
-
Kim DD, Eng C. The current state of targeted agents in rectal cancer. Int J Surg Oncol. 2012; 2012:406830.
PMID: 22675625; PMCID: PMC3362864.
-
Richardson PG, Eng C, Kolesar J, Hideshima T, Anderson KC. Perifosine , an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity. Expert Opin Drug Metab Toxicol. 2012 May; 8(5):623-33.
PMID: 22512706; PMCID: PMC4467022.
Citations:
39 Fields:
Translation:
HumansCells
-
Silva NN, Eng C. Management of refractory metastatic anal squamous cell carcinoma following disease progression on traditional chemoradiation therapy. J Adv Pract Oncol. 2012 May; 3(3):161-9.
PMID: 25031942; PMCID: PMC4093318.
-
Citations:
30 Fields:
Translation:
Humans
-
Boyette-Davis JA, Eng C, Wang XS, Cleeland CS, Wendelschafer-Crabb G, Kennedy WR, Simone DA, Zhang H, Dougherty PM. Subclinical peripheral neuropathy is a common finding in colorectal cancer patients prior to chemotherapy. Clin Cancer Res. 2012 Jun 01; 18(11):3180-7.
PMID: 22496202; PMCID: PMC3619440.
Citations:
26 Fields:
Translation:
Humans
-
Park IJ, You YN, Agarwal A, Skibber JM, Rodriguez-Bigas MA, Eng C, Feig BW, Das P, Krishnan S, Crane CH, Hu CY, Chang GJ. Neoadjuvant treatment response as an early response indicator for patients with rectal cancer. J Clin Oncol. 2012 May 20; 30(15):1770-6.
PMID: 22493423; PMCID: PMC3383178.
Citations:
183 Fields:
Translation:
Humans
-
Garrett CR, Hassabo HM, Bhadkamkar NA, Wen S, Baladandayuthapani V, Kee BK, Eng C, Hassan MM. Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer. Br J Cancer. 2012 Apr 10; 106(8):1374-8.
PMID: 22421948; PMCID: PMC3326682.
Citations:
68 Fields:
Translation:
Humans
-
Lin M, Eng C, Hawk ET, Huang M, Greisinger AJ, Gu J, Ellis LM, Wu X, Lin J. Genetic variants within ultraconserved elements and susceptibility to right- and left-sided colorectal adenocarcinoma. Carcinogenesis. 2012 Apr; 33(4):841-7.
PMID: 22318908; PMCID: PMC3324446.
Citations:
3 Fields:
Translation:
HumansCells
-
Garrett CR, George B, Viswanathan C, Bhadkamkar NA, Wen S, Baladandayuthapani V, You YN, Kopetz ES, Overman MJ, Kee BK, Eng C. Survival benefit associated with surgical oophorectomy in patients with colorectal cancer metastatic to the ovary. Clin Colorectal Cancer. 2012 Sep; 11(3):191-4.
PMID: 22280844.
Citations:
7 Fields:
Translation:
Humans
-
Cheng L, Eng C, Nieman LZ, Kapadia AS, Du XL. Trends in colorectal cancer incidence by anatomic site and disease stage in the United States from 1976 to 2005. Am J Clin Oncol. 2011 Dec; 34(6):573-80.
PMID: 21217399.
Citations:
72 Fields:
Translation:
Humans
-
Pecot CV, Bischoff FZ, Mayer JA, Wong KL, Pham T, Bottsford-Miller J, Stone RL, Lin YG, Jaladurgam P, Roh JW, Goodman BW, Merritt WM, Pircher TJ, Mikolajczyk SD, Nick AM, Celestino J, Eng C, Ellis LM, Deavers MT, Sood AK. A novel platform for detection of CK+ and CK- CTCs. Cancer Discov. 2011 Dec; 1(7):580-6.
PMID: 22180853; PMCID: PMC3237635.
Citations:
86 Fields:
Translation:
HumansCells
-
Eng C. Carcinoma of the anal canal: small steps in treatment advances. Clin Adv Hematol Oncol. 2011 Sep; 9(9):662-9.
PMID: 22402509.
Citations: Fields:
Translation:
Humans
-
Aklilu M, Eng C. The current landscape of locally advanced rectal cancer. Nat Rev Clin Oncol. 2011 Aug 09; 8(11):649-59.
PMID: 21826084.
Citations:
44 Fields:
Translation:
Humans
-
Citations:
4 Fields:
Translation:
Humans
-
El-Khoueiry AB, Rankin CJ, Ben-Josef E, Lenz HJ, Gold PJ, Hamilton RD, Govindarajan R, Eng C, Blanke CD. SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma. Invest New Drugs. 2012 Aug; 30(4):1646-51.
PMID: 21748296; PMCID: PMC3490705.
Citations:
66 Fields:
Translation:
HumansCTClinical Trials
-
Lieu CH, Lambert LA, Wolff RA, Eng C, Zhang N, Wen S, Rafeeq S, Taggart M, Fournier K, Royal R, Mansfield P, Overman MJ. Systemic chemotherapy and surgical cytoreduction for poorly differentiated and signet ring cell adenocarcinomas of the appendix. Ann Oncol. 2012 Mar; 23(3):652-658.
PMID: 21653683; PMCID: PMC3331734.
Citations:
35 Fields:
Translation:
Humans
-
Garrett CR, Eng C. Cetuximab in the treatment of patients with colorectal cancer. Expert Opin Biol Ther. 2011 Jul; 11(7):937-49.
PMID: 21557708.
Citations:
20 Fields:
Translation:
Humans
-
Tanaka M, Chang P, Li Y, Li D, Overman M, Maru DM, Sethi S, Phillips J, Bland GL, Abbruzzese JL, Eng C. Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer. Clin Cancer Res. 2011 Jul 01; 17(13):4531-40.
PMID: 21551253.
Citations:
22 Fields:
Translation:
HumansCells
-
Watkins J, Slade JH, Phan A, Eng C, Weissferdt A, Overman MJ. Fatal diffuse alveolar damage associated with oxaliplatin administration. Clin Colorectal Cancer. 2011 Sep; 10(3):198-202.
PMID: 21855043.
Citations:
6 Fields:
Translation:
Humans
-
Citations:
22 Fields:
Translation:
Humans
-
Brouquet A, Abdalla EK, Kopetz S, Garrett CR, Overman MJ, Eng C, Andreou A, Loyer EM, Madoff DC, Curley SA, Vauthey JN. High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome. J Clin Oncol. 2011 Mar 10; 29(8):1083-90.
PMID: 21263087; PMCID: PMC3068054.
Citations:
119 Fields:
Translation:
Humans
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Tanaka M, Javle M, Dong X, Eng C, Abbruzzese JL, Li D. Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer. Cancer. 2010 Nov 15; 116(22):5325-35.
PMID: 20665488; PMCID: PMC2966859.
Citations:
34 Fields:
Translation:
Humans
-
Pande M, Amos CI, Eng C, Frazier ML. Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis. Mol Carcinog. 2010 Nov; 49(11):974-80.
PMID: 20886582; PMCID: PMC3034292.
Citations:
7 Fields:
Translation:
Humans
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Tsimberidou AM, Fu S, Ng C, Lim JA, Wen S, Hong D, Wheler J, Bedikian AY, Eng C, Wallace M, Camacho LH, Kurzrock R. A phase 1 study of hepatic arterial infusion of oxaliplatin in combination with systemic 5-fluorouracil, leucovorin, and bevacizumab in patients with advanced solid tumors metastatic to the liver. Cancer. 2010 Sep 01; 116(17):4086-94.
PMID: 20564148; PMCID: PMC2930110.
Citations:
7 Fields:
Translation:
HumansCTClinical Trials
-
Eng C. Are herbal medicines ripe for the cancer clinic? Sci Transl Med. 2010 Aug 18; 2(45):45ps41.
PMID: 20720215.
Citations:
6 Fields:
Translation:
HumansAnimals
-
Silberfein EJ, Kattepogu KM, Hu CY, Skibber JM, Rodriguez-Bigas MA, Feig B, Das P, Krishnan S, Crane C, Kopetz S, Eng C, Chang GJ. Long-term survival and recurrence outcomes following surgery for distal rectal cancer. Ann Surg Oncol. 2010 Nov; 17(11):2863-9.
PMID: 20552409; PMCID: PMC3071558.
Citations:
41 Fields:
Translation:
Humans
-
Overman MJ, Maru DM, Charnsangavej C, Loyer EM, Wang H, Pathak P, Eng C, Hoff PM, Vauthey JN, Wolff RA, Kopetz S. Oxaliplatin-mediated increase in spleen size as a biomarker for the development of hepatic sinusoidal injury. J Clin Oncol. 2010 May 20; 28(15):2549-55.
PMID: 20406923.
Citations:
69 Fields:
Translation:
Humans
-
Wang XS, Williams LA, Eng C, Mendoza TR, Shah NA, Kirkendoll KJ, Shah PK, Trask PC, Palos GR, Cleeland CS. Validation and application of a module of the M. D. Anderson Symptom Inventory for measuring multiple symptoms in patients with gastrointestinal cancer (the MDASI-GI). Cancer. 2010 Apr 15; 116(8):2053-63.
PMID: 20166216.
Citations:
27 Fields:
Translation:
Humans
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Das P, Cantor SB, Parker CL, Zampieri JB, Baschnagel A, Eng C, Delclos ME, Krishnan S, Janjan NA, Crane CH. Long-term quality of life after radiotherapy for the treatment of anal cancer. Cancer. 2010 Feb 15; 116(4):822-9.
PMID: 20041481; PMCID: PMC6455911.
Citations:
27 Fields:
Translation:
HumansPHPublic Health
-
Shapiro JF, Chase JL, Wolff RA, Lambert LA, Mansfield PF, Overman MJ, Ohinata A, Liu J, Wang X, Eng C. Modern systemic chemotherapy in surgically unresectable neoplasms of appendiceal origin: a single-institution experience. Cancer. 2010 Jan 15; 116(2):316-22.
PMID: 19904805.
Citations:
37 Fields:
Translation:
Humans
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Eng C. The evolving role of monoclonal antibodies in colorectal cancer: early presumptions and impact on clinical trial development. Oncologist. 2010; 15(1):73-84.
PMID: 20067946; PMCID: PMC3227885.
Citations:
12 Fields:
Translation:
Humans
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Kopetz S, Hoff PM, Morris JS, Wolff RA, Eng C, Glover KY, Adinin R, Overman MJ, Valero V, Wen S, Lieu C, Yan S, Tran HT, Ellis LM, Abbruzzese JL, Heymach JV. Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance. J Clin Oncol. 2010 Jan 20; 28(3):453-9.
PMID: 20008624; PMCID: PMC2815707.
Citations:
186 Fields:
Translation:
HumansCTClinical Trials
-
Citations:
32 Fields:
Translation:
Humans
-
Wong SL, Mangu PB, Choti MA, Crocenzi TS, Dodd GD, Dorfman GS, Eng C, Fong Y, Giusti AF, Lu D, Marsland TA, Michelson R, Poston GJ, Schrag D, Seidenfeld J, Benson AB. American Society of Clinical Oncology 2009 clinical evidence review on radiofrequency ablation of hepatic metastases from colorectal cancer. J Clin Oncol. 2010 Jan 20; 28(3):493-508.
PMID: 19841322.
Citations:
138 Fields:
Translation:
Humans
-
Citations:
38 Fields:
Translation:
Humans
-
Eng C, Kopetz S. Commentary: practice patterns and potential impact on quality measures for a practicing physician. J Oncol Pract. 2009 Sep; 5(5):233-5.
PMID: 20856734; PMCID: PMC2790660.
-
Citations:
28 Fields:
Translation:
HumansPHPublic Health
-
Citations:
14 Fields:
Translation:
Humans
-
Eng C, Pathak P. Treatment options in metastatic squamous cell carcinoma of the anal canal. Curr Treat Options Oncol. 2008 Dec; 9(4-6):400-7.
PMID: 19479383.
Citations:
5 Fields:
Translation:
Humans
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Lambert LA, Armstrong TS, Lee JJ, Liu S, Katz MH, Eng C, Wolff RA, Tortorice ML, Tansey P, Gonzalez-Moreno S, Lambert DH, Mansfield PF. Incidence, risk factors, and impact of severe neutropenia after hyperthermic intraperitoneal mitomycin C. Ann Surg Oncol. 2009 Aug; 16(8):2181-7.
PMID: 19475451; PMCID: PMC2711905.
Citations:
21 Fields:
Translation:
Humans
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Kopetz S, Chang GJ, Overman MJ, Eng C, Sargent DJ, Larson DW, Grothey A, Vauthey JN, Nagorney DM, McWilliams RR. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol. 2009 Aug 01; 27(22):3677-83.
PMID: 19470929; PMCID: PMC2720081.
Citations:
440 Fields:
Translation:
Humans
-
Crane CH, Eng C, Feig BW, Das P, Skibber JM, Chang GJ, Wolff RA, Krishnan S, Hamilton S, Janjan NA, Maru DM, Ellis LM, Rodriguez-Bigas MA. Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3):824-30.
PMID: 19464823.
Citations:
71 Fields:
Translation:
HumansCTClinical Trials
-
Ajani JA, Wang X, Izzo JG, Crane CH, Eng C, Skibber JM, Das P, Rashid A. Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation. Dig Dis Sci. 2010 Apr; 55(4):1098-105.
PMID: 19399614.
Citations:
20 Fields:
Translation:
Humans
-
Eng C. Toxic effects and their management: daily clinical challenges in the treatment of colorectal cancer. Nat Rev Clin Oncol. 2009 Apr; 6(4):207-18.
PMID: 19333227.
Citations:
22 Fields:
Translation:
Humans
-
Hodges JC, Das P, Eng C, Reish AG, Beddar AS, Delclos ME, Krishnan S, Crane CH. Intensity-modulated radiation therapy for the treatment of squamous cell anal cancer with para-aortic nodal involvement. Int J Radiat Oncol Biol Phys. 2009 Nov 01; 75(3):791-4.
PMID: 19231109; PMCID: PMC6455914.
Citations:
7 Fields:
Translation:
Humans
-
Overman MJ, Varadhachary GR, Kopetz S, Adinin R, Lin E, Morris JS, Eng C, Abbruzzese JL, Wolff RA. Phase II study of capecitabine and oxaliplatin for advanced adenocarcinoma of the small bowel and ampulla of Vater. J Clin Oncol. 2009 Jun 01; 27(16):2598-603.
PMID: 19164203.
Citations:
75 Fields:
Translation:
HumansCTClinical Trials
-
Herman MP, Kopetz S, Bhosale PR, Eng C, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Delclos ME, Krishnan S, Crane CH, Das P. Sacral insufficiency fractures after preoperative chemoradiation for rectal cancer: incidence, risk factors, and clinical course. Int J Radiat Oncol Biol Phys. 2009 Jul 01; 74(3):818-23.
PMID: 19147305; PMCID: PMC3071557.
Citations:
19 Fields:
Translation:
Humans
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Eng C, Crane CH, Rodriguez-Bigas MA. Should cisplatin be avoided in the treatment of locally advanced squamous cell carcinoma of the anal canal? Nat Clin Pract Gastroenterol Hepatol. 2009 Jan; 6(1):16-7.
PMID: 19047998.
-
Citations:
5 Fields:
Translation:
HumansAnimalsCells
-
Blazer DG, Kishi Y, Maru DM, Kopetz S, Chun YS, Overman MJ, Fogelman D, Eng C, Chang DZ, Wang H, Zorzi D, Ribero D, Ellis LM, Glover KY, Wolff RA, Curley SA, Abdalla EK, Vauthey JN. Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. J Clin Oncol. 2008 Nov 20; 26(33):5344-51.
PMID: 18936472.
Citations:
175 Fields:
Translation:
Humans
-
Overman MJ, Fogelman D, Al-Kali A, Crane CH, Evans D, Abdalla EK, Pisters P, Kopetz S, Eng C, Wolff RA. Aggressive combined modality therapy for recurrent colorectal cancer involving the duodenum and pancreas: a report of 5 cases. Clin Colorectal Cancer. 2008 Sep; 7(5):338-42.
PMID: 18794067.
Citations: Fields:
Translation:
Humans
-
Kopetz S, Overman M, Chang DZ, Glover KY, Shureiqi I, Wolff RA, Abbruzzese JL, Eng C. Systematic survey of therapeutic trials for metastatic colorectal cancer: room for improvement in the critical pathway. J Clin Oncol. 2008 Apr 20; 26(12):2000-5.
PMID: 18421052.
Citations:
2 Fields:
Translation:
Humans
-
Sobrero AF, Maurel J, Fehrenbacher L, Scheithauer W, Abubakr YA, Lutz MP, Vega-Villegas ME, Eng C, Steinhauer EU, Prausova J, Lenz HJ, Borg C, Middleton G, Luppi G, Kisker O, Zubel A, Langer C, Kopit J, Burris HA, Kr?ning H. EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. J Clin Oncol. 2008 May 10; 26(14):2311-9.
PMID: 18390971.
Citations:
306 Fields:
Translation:
HumansCTClinical Trials
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Eng C. K-Ras and sensitivity to EGFR inhibitors in metastatic colorectal cancer. Clin Adv Hematol Oncol. 2008 Mar; 6(3):174-5.
PMID: 18391915.
Citations:
2 Fields:
Translation:
Humans
-
Yu TK, Bhosale PR, Crane CH, Iyer RB, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Eng C, Wolff RA, Janjan NA, Delclos ME, Krishnan S, Das P. Patterns of locoregional recurrence after surgery and radiotherapy or chemoradiation for rectal cancer. Int J Radiat Oncol Biol Phys. 2008 Jul 15; 71(4):1175-80.
PMID: 18207667; PMCID: PMC6455925.
Citations:
20 Fields:
Translation:
Humans
-
Politano S, Overman M, Pathak P, Chadha R, Glover K, Chang DZ, Wolff RA, Hoff PM, Abbruzzese J, Eng C, Kopetz S. Second-line chemotherapy use in metastatic colon cancer varies by disease responsiveness. Clin Colorectal Cancer. 2008 Jan; 7(1):55-9.
PMID: 18279578.
Citations:
4 Fields:
Translation:
Humans
-
Bhaskara A, Eng C. Bevacizumab in the treatment of a patient with metastatic colorectal carcinoma with brain metastases. Clin Colorectal Cancer. 2008 Jan; 7(1):65-8.
PMID: 18279580.
Citations:
9 Fields:
Translation:
Humans
-
Das P, Crane CH, Eng C, Ajani JA. Prognostic factors for squamous cell cancer of the anal canal. Gastrointest Cancer Res. 2008 Jan; 2(1):10-4.
PMID: 19259318; PMCID: PMC2630809.
-
Ribero D, Wang H, Donadon M, Zorzi D, Thomas MB, Eng C, Chang DZ, Curley SA, Abdalla EK, Ellis LM, Vauthey JN. Bevacizumab improves pathologic response and protects against hepatic injury in patients treated with oxaliplatin-based chemotherapy for colorectal liver metastases. Cancer. 2007 Dec 15; 110(12):2761-7.
PMID: 17960603.
Citations:
118 Fields:
Translation:
Humans
-
Murthy R, Eng C, Krishnan S, Madoff DC, Habbu A, Canet S, Hicks ME. Hepatic yttrium-90 radioembolotherapy in metastatic colorectal cancer treated with cetuximab or bevacizumab. J Vasc Interv Radiol. 2007 Dec; 18(12):1588-91.
PMID: 18057297.
Citations:
9 Fields:
Translation:
Humans
-
Badgwell BD, Camp ER, Feig B, Wolff RA, Eng C, Ellis LM, Cormier JN. Management of bevacizumab-associated bowel perforation: a case series and review of the literature. Ann Oncol. 2008 Mar; 19(3):577-82.
PMID: 18024857.
Citations:
35 Fields:
Translation:
Humans
-
Eng C. Combining targeted therapies to enhance the effectiveness of chemotherapy in patients with treatment-refractory colorectal cancer. Clin Colorectal Cancer. 2007 Oct; 6 Suppl 2:S53-9.
PMID: 18021488.
Citations: Fields:
Translation:
HumansCells
-
Chun YS, Vauthey JN, Ribero D, Donadon M, Mullen JT, Eng C, Madoff DC, Chang DZ, Ho L, Kopetz S, Wei SH, Curley SA, Abdalla EK. Systemic chemotherapy and two-stage hepatectomy for extensive bilateral colorectal liver metastases: perioperative safety and survival. J Gastrointest Surg. 2007 Nov; 11(11):1498-504; discussion 1504-5.
PMID: 17849166.
Citations:
41 Fields:
Translation:
Humans
-
Citations:
124 Fields:
Translation:
Humans
-
Das P, Bhatia S, Eng C, Ajani JA, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Bhosale P, Delclos ME, Krishnan S, Janjan NA, Crane CH. Predictors and patterns of recurrence after definitive chemoradiation for anal cancer. Int J Radiat Oncol Biol Phys. 2007 Jul 01; 68(3):794-800.
PMID: 17379452.
Citations:
50 Fields:
Translation:
HumansCTClinical Trials
-
-
Swartz RJ, de Moor C, Cook KF, Fouladi RT, Basen-Engquist K, Eng C, Carmack Taylor CL. Mode effects in the center for epidemiologic studies depression (CES-D) scale: personal digital assistant vs. paper and pencil administration. Qual Life Res. 2007 Jun; 16(5):803-13.
PMID: 17295102.
Citations:
15 Fields:
Translation:
Humans
-
Malik Z, Eng C. The use cetuximab after oxaliplatin-based chemotherapy in a patient with metastatic colorectal cancer. Clin Adv Hematol Oncol. 2007 Jan; 5(1 Suppl 1):4-7.
PMID: 17491584.
Citations: Fields:
Translation:
Humans
-
Krishnan S, Janjan NA, Skibber JM, Rodriguez-Bigas MA, Wolff RA, Das P, Delclos ME, Chang GJ, Hoff PM, Eng C, Brown TD, Crane CH, Feig BW, Morris J, Vadhan-Raj S, Hamilton SR, Lin EH. Phase II study of capecitabine (Xeloda) and concomitant boost radiotherapy in patients with locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2006 Nov 01; 66(3):762-71.
PMID: 17011451.
Citations:
44 Fields:
Translation:
HumansCTClinical Trials
-
Das P, Lin EH, Bhatia S, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Hoff PM, Eng C, Wolff RA, Delclos ME, Krishnan S, Janjan NA, Crane CH. Preoperative chemoradiotherapy with capecitabine versus protracted infusion 5-fluorouracil for rectal cancer: a matched-pair analysis. Int J Radiat Oncol Biol Phys. 2006 Dec 01; 66(5):1378-83.
PMID: 17056196.
Citations:
25 Fields:
Translation:
Humans
-
Eng C. Anal cancer: current and future methodology. Cancer Invest. 2006 Aug-Sep; 24(5):535-44.
PMID: 16939964.
Citations:
17 Fields:
Translation:
Humans
-
Eng C, Shalan N. Biological agents versus chemotherapy in the treatment of colorectal cancer. Expert Opin Pharmacother. 2006 Jul; 7(10):1251-71.
PMID: 16805714.
Citations:
1 Fields:
Translation:
Humans
-
Das P, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Hoff PM, Eng C, Wolff RA, Janjan NA, Delclos ME, Krishnan S, Levy LB, Ellis LM, Crane CH. Clinical and pathologic predictors of locoregional recurrence, distant metastasis, and overall survival in patients treated with chemoradiation and mesorectal excision for rectal cancer. Am J Clin Oncol. 2006 Jun; 29(3):219-24.
PMID: 16755173.
Citations:
56 Fields:
Translation:
Humans
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Hoff PM, Wolff RA, Xiong H, Jones D, Lin E, Eng C, Dutta A, Bogaard KR, Abbruzzese JL. Phase II trial of combined irinotecan and oxaliplatin given every 3 weeks to patients with metastatic colorectal cancer. Cancer. 2006 May 15; 106(10):2241-6.
PMID: 16598762.
Citations: Fields:
Translation:
HumansCTClinical Trials
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Vauthey JN, Pawlik TM, Ribero D, Wu TT, Zorzi D, Hoff PM, Xiong HQ, Eng C, Lauwers GY, Mino-Kenudson M, Risio M, Muratore A, Capussotti L, Curley SA, Abdalla EK. Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. J Clin Oncol. 2006 May 01; 24(13):2065-72.
PMID: 16648507.
Citations:
373 Fields:
Translation:
Humans
-
Abdalla EK, Eng C, Madary A, Vauthey JN, Southwest Oncology Group 0408. Southwest Oncology Group 0408: Phase II trial of neoadjuvant capecitabine/oxaliplatin/bevacizumab for resectable colorectal metastases in the liver. Clin Colorectal Cancer. 2006 Mar; 5(6):436-9.
PMID: 16635283.
Citations:
1 Fields:
Translation:
Humans
-
Pawlik TM, Scoggins CR, Zorzi D, Abdalla EK, Andres A, Eng C, Curley SA, Loyer EM, Muratore A, Mentha G, Capussotti L, Vauthey JN. Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases. Ann Surg. 2005 May; 241(5):715-22, discussion 722-4.
PMID: 15849507; PMCID: PMC1357126.
Citations:
369 Fields:
Translation:
Humans
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Eng C, Ramanathan RK, Ramathan RK, Wong MK, Remick SC, Dai L, Wade-Oliver KT, Mani S, Kindler HL. A Phase II trial of fixed dose rate gemcitabine in patients with advanced biliary tree carcinoma. Am J Clin Oncol. 2004 Dec; 27(6):565-9.
PMID: 15577433.
Citations:
11 Fields:
Translation:
HumansCTClinical Trials
-
Bonnen M, Crane C, Vauthey JN, Skibber J, Delclos ME, Rodriguez-Bigas M, Hoff PM, Lin E, Eng C, Wong A, Janjan NA, Feig BW. Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients. Int J Radiat Oncol Biol Phys. 2004 Nov 15; 60(4):1098-105.
PMID: 15519780.
Citations:
39 Fields:
Translation:
Humans
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Eng C, Abbruzzese JL. The treatment of colorectal carcinoma: standard chemotherapy and beyond. Clin Adv Hematol Oncol. 2004 Sep; 2(9):592-8.
PMID: 16163242.
Citations: Fields:
Translation:
Humans
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Milano MT, Haraf DJ, Stenson KM, Witt ME, Eng C, Mittal BB, Argiris A, Pelzer H, Kozloff MF, Vokes EE. Phase I study of concomitant chemoradiotherapy with paclitaxel, fluorouracil, gemcitabine, and twice-daily radiation in patients with poor-prognosis cancer of the head and neck. Clin Cancer Res. 2004 Aug 01; 10(15):4922-32.
PMID: 15297392.
Citations:
8 Fields:
Translation:
HumansCTClinical Trials
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Eng C, Kindler HL, Nattam S, Ansari RH, Kasza K, Wade-Oliver K, Vokes EE. A phase II trial of the epothilone B analog, BMS-247550, in patients with previously treated advanced colorectal cancer. Ann Oncol. 2004 Jun; 15(6):928-32.
PMID: 15151950.
Citations:
7 Fields:
Translation:
HumansCTClinical Trials
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Eng C, Abbruzzese J, Minsky BD. Chemotherapy and radiation of anal canal cancer: the first approach. Surg Oncol Clin N Am. 2004 Apr; 13(2):309-20, viii.
PMID: 15137959.
Citations:
3 Fields:
Translation:
Humans
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Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment. Annals of Oncology. 26:731-736.
-
Impact of multimodal therapy in locally recurrent rectal cancer. British Journal of Surgery. 103:753-762.
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Transthoracic Port Placement Increases Safety of Total Laparoscopic Posterior Sectionectomy. Annals of Surgical Oncology. 1.
-
Colon cancer. 77-84.
-
American society of clinical oncology statement. Journal of Clinical Oncology. 34:1803-1812.
-
Colorectal cancer survivorship management. 71-93.
-
Oncologic and Functional Hazards of Obesity Among Patients With Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiation Therapy. American Journal of Clinical Oncology: Cancer Clinical Trials.
-
Metastatic Anal Cancer and Novel Agents. Surgical Oncology Clinics of North America. 26:133-142.
-
Epidermal growth factor receptor inhibition in metastatic anal cancer. Anti-Cancer Drugs. 27:804-808.
-
Hyperfractionated accelerated reirradiation for rectal cancer. Radiotherapy and Oncology.
-
Definitive chemoradiation in oligometastatic squamous cell carcinoma of the anal canal. Gastrointestinal Cancer Research. 7:65-68.
-
Cetuximab in combination with cisplatin and 5-Fluorouracil induces dramatic response in metastatic refractory squamous cell carcinoma of the anal canal. Journal of Gastrointestinal Oncology. 6:E82-E85.
-
Clinical implications of circulating tumor cells in advanced colorectal cancer. Current Colorectal Cancer Reports. 8:233-242.
-
Hyperfractionated Accelerated Reirradiation for Patients With Recurrent Anal Cancer Previously Treated With Definitive Chemoradiation. American Journal of Clinical Oncology: Cancer Clinical Trials.
-
Pathologic complete response in poorly differentiated adenocarcinomas of the appendix. Acta Oncologica. 52:1046-1048.
-
Cancer of the anal region.
-
Potential Prognostic Impact of Baseline CEA Level and Surgery of Primary Tumor Among Patients with Synchronous Stage IV Colorectal Cancer. Indian Journal of Surgical Oncology. 6:198-206.
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The treatment of colorectal cancer during pregnancy. Oncologist. 21:563-570.
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Erratum. American Journal of Clinical Oncology: Cancer Clinical Trials. 28:455.
-
Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer. Oncotarget. 7:76250-76260.
-
POLE mutations in colorectal cancer. The Lancet Gastroenterology and Hepatology. 1:176-177.
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Preface. Surgical Oncology Clinics of North America.
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Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer. Investigational New Drugs.
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Retreatment with anti-EGFR based therapies in metastatic colorectal cancer. BMC Cancer. 15.
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MET amplification in metastatic colorectal cancer. Oncotarget. 7:54627-54631.
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Long-Term results of weekly/daily cisplatin-Based chemoradiation for locally advanced squamous cell carcinoma of the anal canal. Diseases of the Colon and Rectum. 57.
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Multidisciplinary management of stage IV colon cancer. Seminars in Colon and Rectal Surgery.
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Colon, rectal, and anal cancer management. 711-739.
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Prechemotherapy Touch Sensation Deficits Predict Oxaliplatin-Induced Neuropathy in Patients with Colorectal Cancer. Oncology (Switzerland).
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Definitive Chemoradiation for Squamous Cell Carcinoma of the Rectum. American Journal of Clinical Oncology: Cancer Clinical Trials.
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Total Transthoracic Approach Facilitates Laparoscopic Hepatic Resection in Patients with Significant Prior Abdominal Surgery. Annals of Surgical Oncology. 1-2.
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Current and emerging trends in the treatment of metastatic colorectal cancer. Hematology/Oncology Clinics of North America. 21:8-17.
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Colorectal Cancer. 86-136.
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Low-grade Appendiceal Mucinous Neoplasm of Uncertain Malignant Potential (LAMN-UMP). Annals of Surgical Oncology. 1-7.
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Intensity-modulated radiation therapy with concurrent chemotherapy for anal cancer outcomes and toxicity. American Journal of Clinical Oncology: Cancer Clinical Trials. 37:461-466.
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Building on the foundation of 5-FU to treat metastatic colorectal cancer. Oncology. 22:462-468.
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Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials. Annals of Oncology. 27:1068-1074.
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Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer. Oncotarget. 7:67495-67506.