InstitutionMD Anderson
DepartmentPain Medicine
Address1400 Holcombe Blvd
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li Y, Marri T, North RY, Rhodes HR, Uhelski ML, Tatsui CE, Rhines LD, Rao G, Corrales G, Abercrombie TJ, Johansson CA, Dougherty PM. Chemotherapy-induced peripheral neuropathy in a dish: dorsal root ganglion cells treated in vitro with paclitaxel show biochemical and physiological responses parallel to that seen in vivo. Pain. 2021 Jan; 162(1):84-96. PMID: 32694383.
      Citations:    Fields:    
    2. Silverman DA, Martinez VK, Dougherty PM, Myers JN, Calin GA, Amit M. Cancer-associated neurogenesis and nerve-cancer crosstalk. Cancer Res. 2020 Dec 17. PMID: 33334813.
      Citations:    Fields:    
    3. Gorniak SL, Ochoa N, Cox LIG, Khan A, Ansari S, Thames B, Ray H, Lu YF, Hibino H, Watson N, Dougherty PM. Sex-based differences and aging in tactile function loss in persons with type 2 diabetes. PLoS One. 2020; 15(11):e0242199. PMID: 33180801.
      Citations: 1     Fields:    Translation:Humans
    4. Shiers S, Ray PR, Wangzhou A, Sankaranarayanan I, Tatsui CE, Rhines LD, Li Y, Uhelski ML, Dougherty PM, Price TJ. ACE2 and SCARF expression in human dorsal root ganglion nociceptors: implications for SARS-CoV-2 virus neurological effects. Pain. 2020 11; 161(11):2494-2501. PMID: 32826754.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    5. Kim HK, Bae J, Lee SH, Hwang SH, Kim MS, Kim MJ, Jun S, Cervantes CL, Jung YS, Back S, Lee H, Lee SE, Dougherty PM, Lee SW, Park JI, Abdi S. Blockers of Wnt3a, Wnt10a, or ß-Catenin Prevent Chemotherapy-Induced Neuropathic Pain In Vivo. Neurotherapeutics. 2020 Oct 30. PMID: 33128175.
      Citations:    Fields:    
    6. Viswanathan A, Vedantam A, Williams LA, Koyyalagunta D, Abdi S, Dougherty PM, Mendoza T, Bassett RL, Hou P, Bruera E. Percutaneous Cordotomy for Pain Palliation in Advanced Cancer: A Randomized Clinical Trial Study Protocol. Neurosurgery. 2020 08 01; 87(2):394-402. PMID: 32012217.
      Citations:    Fields:    
    7. Zhang D, Zhou W, Lam TT, Li Y, Duman JG, Dougherty PM, Grosshans DR. Cranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa058. PMID: 32642710.
    8. Cata JP, Patino M, Gorur A, Du KN, Uhelski ML, Myers J, Lai S, Rubin ML, Dougherty PM, Owusu-Agyemang P. Persistent and Chronic Postoperative Opioid Use in a Cohort of Patients with Oral Tongue Squamous Cell Carcinoma. Pain Med. 2020 05 01; 21(5):1061-1067. PMID: 31609416.
      Citations:    Fields:    
    9. Amit M, Takahashi H, Dragomir MP, Lindemann A, Gleber-Netto FO, Pickering CR, Anfossi S, Osman AA, Cai Y, Wang R, Knutsen E, Shimizu M, Ivan C, Rao X, Wang J, Silverman DA, Tam S, Zhao M, Caulin C, Zinger A, Tasciotti E, Dougherty PM, El-Naggar A, Calin GA, Myers JN. Loss of p53 drives neuron reprogramming in head and neck cancer. Nature. 2020 02; 578(7795):449-454. PMID: 32051587.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    10. Dougherty PM. Should we be itching for a CCL2 itch and pain medicine? Brain Behav Immun. 2019 10; 81:12-13. PMID: 31271874.
      Citations:    Fields:    Translation:Animals
    11. Vedantam A, Bruera E, Hess KR, Dougherty PM, Viswanathan A. Somatotopy and Organization of Spinothalamic Tracts in the Human Cervical Spinal Cord. Neurosurgery. 2019 06 01; 84(6):E311-E317. PMID: 30011044.
      Citations:    Fields:    Translation:Humans
    12. North RY, Li Y, Ray P, Rhines LD, Tatsui CE, Rao G, Johansson CA, Zhang H, Kim YH, Zhang B, Dussor G, Kim TH, Price TJ, Dougherty PM. Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons. Brain. 2019 05 01; 142(5):1215-1226. PMID: 30887021.
      Citations: 28     Fields:    Translation:HumansCells
    13. Viswanathan A, Vedantam A, Hess KR, Ochoa J, Dougherty PM, Reddy AS, Koyyalagunta D, Reddy S, Bruera E. Minimally Invasive Cordotomy for Refractory Cancer Pain: A Randomized Controlled Trial. Oncologist. 2019 07; 24(7):e590-e596. PMID: 30796153.
      Citations: 1     Fields:    Translation:Humans
    14. Megat S, Ray PR, Moy JK, Lou TF, Barragán-Iglesias P, Li Y, Pradhan G, Wanghzou A, Ahmad A, Burton MD, North RY, Dougherty PM, Khoutorsky A, Sonenberg N, Webster KR, Dussor G, Campbell ZT, Price TJ. Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain. J Neurosci. 2019 01 16; 39(3):393-411. PMID: 30459229.
      Citations: 26     Fields:    Translation:AnimalsCells
    15. Vedantam A, Koyyalagunta D, Bruel BM, Dougherty PM, Viswanathan A. Limited Midline Myelotomy for Intractable Visceral Pain: Surgical Techniques and Outcomes. Neurosurgery. 2018 10 01; 83(4):783-789. PMID: 29165656.
      Citations: 2     Fields:    Translation:Humans
    16. Boyette-Davis JA, Hou S, Abdi S, Dougherty PM. An updated understanding of the mechanisms involved in chemotherapy-induced neuropathy. Pain Manag. 2018 Sep 01; 8(5):363-375. PMID: 30212277.
      Citations: 12     Fields:    Translation:HumansAnimals
    17. North RY, Lazaro TT, Dougherty PM. Ectopic Spontaneous Afferent Activity and Neuropathic Pain. Neurosurgery. 2018 09 01; 65(CN_suppl_1):49-54. PMID: 31076785.
      Citations: 2     Fields:    
    18. Zhang D, Zhou W, Lam TT, Weng C, Bronk L, Ma D, Wang Q, Duman JG, Dougherty PM, Grosshans DR. Radiation induces age-dependent deficits in cortical synaptic plasticity. Neuro Oncol. 2018 08 02; 20(9):1207-1214. PMID: 29660023.
      Citations: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    19. Gewandter JS, Brell J, Cavaletti G, Dougherty PM, Evans S, Howie L, McDermott MP, O'Mara A, Smith AG, Dastros-Pitei D, Gauthier LR, Haroutounian S, Jarpe M, Katz NP, Loprinzi C, Richardson P, Lavoie-Smith EM, Wen PY, Turk DC, Dworkin RH, Freeman R. Trial designs for chemotherapy-induced peripheral neuropathy prevention: ACTTION recommendations. Neurology. 2018 08 28; 91(9):403-413. PMID: 30054438.
      Citations: 11     Fields:    Translation:Humans
    20. Illias AM, Gist AC, Zhang H, Kosturakis AK, Dougherty PM. Chemokine CCL2 and its receptor CCR2 in the dorsal root ganglion contribute to oxaliplatin-induced mechanical hypersensitivity. Pain. 2018 Jul; 159(7):1308-1316. PMID: 29554018.
      Citations: 7     Fields:    Translation:Animals
    21. Roldan CJ, Johnson C, Lee SO, Peng A, Dougherty PM, Huh B. Subclinical Peripheral Neuropathy in Patients with Head and Neck Cancer: A Quantitative Sensory Testing (QST) Study. Pain Physician. 2018 07; 21(4):E419-E427. PMID: 30045608.
      Citations: 2     Fields:    Translation:Humans
    22. Zhang H, Li Y, Yang Q, Liu XG, Dougherty PM. Morphological and Physiological Plasticity of Spinal Lamina II GABA Neurons Is Induced by Sciatic Nerve Chronic Constriction Injury in Mice. Front Cell Neurosci. 2018; 12:143. PMID: 29881336.
    23. Singhmar P, Huo X, Li Y, Dougherty PM, Mei F, Cheng X, Heijnen CJ, Kavelaars A. Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy. Pain. 2018 May; 159(5):884-893. PMID: 29369966.
      Citations: 6     Fields:    Translation:AnimalsCells
    24. Ma J, Kavelaars A, Dougherty PM, Heijnen CJ. Beyond symptomatic relief for chemotherapy-induced peripheral neuropathy: Targeting the source. Cancer. 2018 06 01; 124(11):2289-2298. PMID: 29461625.
      Citations: 27     Fields:    Translation:HumansCells
    25. Li Y, North RY, Rhines LD, Tatsui CE, Rao G, Edwards DD, Cassidy RM, Harrison DS, Johansson CA, Zhang H, Dougherty PM. DRG Voltage-Gated Sodium Channel 1.7 Is Upregulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain. J Neurosci. 2018 01 31; 38(5):1124-1136. PMID: 29255002.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    26. Flatters SJL, Dougherty PM, Colvin LA. Clinical and preclinical perspectives on Chemotherapy-Induced Peripheral Neuropathy (CIPN): a narrative review. Br J Anaesth. 2017 Oct 01; 119(4):737-749. PMID: 29121279.
      Citations: 24     Fields:    Translation:HumansAnimals
    27. Chien JH, Korzeniewska A, Colloca L, Campbell C, Dougherty P, Lenz F. Human Thalamic Somatosensory Nucleus (Ventral Caudal, Vc) as a Locus for Stimulation by INPUTS from Tactile, Noxious and Thermal Sensors on an Active Prosthesis. Sensors (Basel). 2017 May 24; 17(6). PMID: 28538681.
      Citations: 2     Fields:    Translation:HumansCells
    28. Roldan CJ, Song J, Engle MP, Dougherty PM. Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Modulate the Function of Myelinated Fibers after Chemotherapy: A Quantitative Sensory Testing Study. Pain Physician. 2017 05; 20(4):281-292. PMID: 28535551.
      Citations: 3     Fields:    Translation:Humans
    29. Trahan LH, Cox-Martin E, Johnson CE, Dougherty PM, Yu J, Feng L, Cook C, Novy DM. Psychometric Study of the Pain Drawing. J Appl Biobehav Res. 2017 Dec; 22(4). PMID: 29230086.
    30. Li Y, Tatsui CE, Rhines LD, North RY, Harrison DS, Cassidy RM, Johansson CA, Kosturakis AK, Edwards DD, Zhang H, Dougherty PM. Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy. Pain. 2017 03; 158(3):417-429. PMID: 27902567.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    31. Vedantam A, Hou P, Chi TL, Hess KR, Dougherty PM, Bruera E, Viswanathan A. Postoperative MRI Evaluation of a Radiofrequency Cordotomy Lesion for Intractable Cancer Pain. AJNR Am J Neuroradiol. 2017 Apr; 38(4):835-839. PMID: 28209581.
      Citations:    Fields:    Translation:Humans
    32. Cox-Martin E, Trahan LH, Cox MG, Dougherty PM, Lai EA, Novy DM. Disease burden and pain in obese cancer patients with chemotherapy-induced peripheral neuropathy. Support Care Cancer. 2017 06; 25(6):1873-1879. PMID: 28124735.
      Citations: 6     Fields:    Translation:Humans
    33. Vedantam A, Hou P, Chi TL, Dougherty PM, Hess KR, Viswanathan A. Use of Spinal Cord Diffusion Tensor Imaging to Quantify Neural Ablation and Evaluate Outcome after Percutaneous Cordotomy for Intractable Cancer Pain. Stereotact Funct Neurosurg. 2017; 95(1):34-39. PMID: 28088799.
      Citations: 1     Fields:    Translation:Humans
    34. Paice JA, Mulvey M, Bennett M, Dougherty PM, Farrar JT, Mantyh PW, Miaskowski C, Schmidt B, Smith TJ. AAPT Diagnostic Criteria for Chronic Cancer Pain Conditions. J Pain. 2017 03; 18(3):233-246. PMID: 27884691.
      Citations: 6     Fields:    Translation:Humans
    35. Abdi S, Dougherty PM. Chemotherapy-Induced Peripheral Neuropathy: A Challenge for Clinicians. Oncology (Williston Park). 2016 11 15; 30(11):1030, C3. PMID: 27854105.
      Citations:    Fields:    Translation:Humans
    36. Krukowski K, Eijkelkamp N, Laumet G, Hack CE, Li Y, Dougherty PM, Heijnen CJ, Kavelaars A. CD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain. J Neurosci. 2016 10 26; 36(43):11074-11083. PMID: 27798187.
      Citations: 42     Fields:    Translation:AnimalsCells
    37. Pachman DR, Qin R, Seisler D, Smith EM, Kaggal S, Novotny P, Ruddy KJ, Lafky JM, Ta LE, Beutler AS, Wagner-Johnston ND, Staff NP, Grothey A, Dougherty PM, Cavaletti G, Loprinzi CL. Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Support Care Cancer. 2016 12; 24(12):5059-5068. PMID: 27534963.
      Citations: 8     Fields:    Translation:Humans
    38. Dougherty PM, Chen J. Relationship of membrane properties, spike burst responses, laminar location, and functional class of dorsal horn neurons recorded in vitro. J Neurophysiol. 2016 09 01; 116(3):1137-51. PMID: 27334950.
      Citations:    Fields:    Translation:AnimalsCells
    39. Dougherty PM. Is Chemotherapy-induced Peripheral Neuropathy More Than Just a Peripheral Nervous System Disorder? Anesthesiology. 2016 May; 124(5):992-3. PMID: 26978409.
      Citations: 3     Fields:    Translation:Humans
    40. Zhang H, Li Y, de Carvalho-Barbosa M, Kavelaars A, Heijnen CJ, Albrecht PJ, Dougherty PM. Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy. J Pain. 2016 07; 17(7):775-86. PMID: 26979998.
      Citations: 49     Fields:    Translation:AnimalsCells
    41. Wang XS, Shi Q, Dougherty PM, Eng C, Mendoza TR, Williams LA, Fogelman DR, Cleeland CS. Prechemotherapy Touch Sensation Deficits Predict Oxaliplatin-Induced Neuropathy in Patients with Colorectal Cancer. Oncology. 2016; 90(3):127-35. PMID: 26882477.
      Citations: 9     Fields:    Translation:Humans
    42. Ganz PA, Dougherty PM. Painful Hands and Feet After Cancer Treatment: Inflammation Affecting the Mind-Body Connection. J Clin Oncol. 2016 Mar 01; 34(7):649-52. PMID: 26700128.
      Citations: 3     Fields:    Translation:Humans
    43. Li Y, Adamek P, Zhang H, Tatsui CE, Rhines LD, Mrozkova P, Li Q, Kosturakis AK, Cassidy RM, Harrison DS, Cata JP, Sapire K, Zhang H, Kennamer-Chapman RM, Jawad AB, Ghetti A, Yan J, Palecek J, Dougherty PM. The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4. J Neurosci. 2015 Sep 30; 35(39):13487-500. PMID: 26424893.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    44. Shah N, Shi Q, Williams LA, Mendoza TR, Wang XS, Reuben JM, Dougherty PM, Bashir Q, Qazilbash MH, Champlin RE, Cleeland CS, Giralt SA. Higher Stem Cell Dose Infusion after Intensive Chemotherapy Does Not Improve Symptom Burden in Older Patients with Multiple Myeloma and Amyloidosis. Biol Blood Marrow Transplant. 2016 Feb; 22(2):226-231. PMID: 26253006.
      Citations: 3     Fields:    Translation:HumansCells
    45. Mendoza TR, Wang XS, Williams LA, Shi Q, Vichaya EG, Dougherty PM, Thomas SK, Yucel E, Bastida CC, Woodruff JF, Cleeland CS. Measuring Therapy-Induced Peripheral Neuropathy: Preliminary Development and Validation of the Treatment-Induced Neuropathy Assessment Scale. J Pain. 2015 Oct; 16(10):1032-43. PMID: 26210041.
      Citations: 5     Fields:    Translation:Humans
    46. Boyette-Davis JA, Walters ET, Dougherty PM. Mechanisms involved in the development of chemotherapy-induced neuropathy. Pain Manag. 2015; 5(4):285-96. PMID: 26087973.
      Citations: 36     Fields:    Translation:HumansCells
    47. Li Y, Zhang H, Kosturakis AK, Cassidy RM, Zhang H, Kennamer-Chapman RM, Jawad AB, Colomand CM, Harrison DS, Dougherty PM. MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy. Brain Behav Immun. 2015 Oct; 49:255-66. PMID: 26065826.
      Citations: 31     Fields:    Translation:AnimalsCells
    48. Kim JH, Dougherty PM, Abdi S. Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy. Gynecol Oncol. 2015 Mar; 136(3):453-9. PMID: 25584767.
      Citations: 15     Fields:    Translation:Humans
    49. Robinson CR, Dougherty PM. Spinal astrocyte gap junction and glutamate transporter expression contributes to a rat model of bortezomib-induced peripheral neuropathy. Neuroscience. 2015 Jan 29; 285:1-10. PMID: 25446343.
      Citations: 7     Fields:    Translation:AnimalsCells
    50. Colvin LA, Dougherty PM. Peripheral neuropathic pain: signs, symptoms, mechanisms, and causes: are they linked? Br J Anaesth. 2015 Mar; 114(3):361-3. PMID: 25253232.
      Citations: 7     Fields:    Translation:HumansAnimals
    51. de Carvalho Barbosa M, Kosturakis AK, Eng C, Wendelschafer-Crabb G, Kennedy WR, Simone DA, Wang XS, Cleeland CS, Dougherty PM. A quantitative sensory analysis of peripheral neuropathy in colorectal cancer and its exacerbation by oxaliplatin chemotherapy. Cancer Res. 2014 Nov 01; 74(21):5955-62. PMID: 25183707.
      Citations: 17     Fields:    Translation:Humans
    52. Kosturakis AK, He Z, Li Y, Boyette-Davis JA, Shah N, Thomas SK, Zhang H, Vichaya EG, Wang XS, Wendelschafer-Crabb G, Kennedy WR, Simone DA, Cleeland CS, Dougherty PM. Subclinical peripheral neuropathy in patients with multiple myeloma before chemotherapy is correlated with decreased fingertip innervation density. J Clin Oncol. 2014 Oct 01; 32(28):3156-62. PMID: 25154818.
      Citations: 13     Fields:    Translation:Humans
    53. Robinson CR, Zhang H, Dougherty PM. Altered discharges of spinal neurons parallel the behavioral phenotype shown by rats with bortezomib related chemotherapy induced peripheral neuropathy. Brain Res. 2014 Jul 29; 1574:6-13. PMID: 24949562.
      Citations: 5     Fields:    Translation:AnimalsCells
    54. Robinson CR, Zhang H, Dougherty PM. Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat. Neuroscience. 2014 Aug 22; 274:308-17. PMID: 24905437.
      Citations: 41     Fields:    Translation:AnimalsCells
    55. Zhang H, Dougherty PM. Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy. Anesthesiology. 2014 Jun; 120(6):1463-75. PMID: 24534904.
      Citations: 39     Fields:    Translation:AnimalsCells
    56. Li Y, Zhang H, Zhang H, Kosturakis AK, Jawad AB, Dougherty PM. Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy. J Pain. 2014 Jul; 15(7):712-25. PMID: 24755282.
      Citations: 73     Fields:    Translation:AnimalsCells
    57. Gregory NS, Harris AL, Robinson CR, Dougherty PM, Fuchs PN, Sluka KA. An overview of animal models of pain: disease models and outcome measures. J Pain. 2013 Nov; 14(11):1255-69. PMID: 24035349.
      Citations: 68     Fields:    Translation:Animals
    58. Zhang H, Zhang H, Dougherty PM. Dynamic effects of TNF-a on synaptic transmission in mice over time following sciatic nerve chronic constriction injury. J Neurophysiol. 2013 Oct; 110(7):1663-71. PMID: 23864372.
      Citations: 15     Fields:    Translation:AnimalsCells
    59. Zhang H, Boyette-Davis JA, Kosturakis AK, Li Y, Yoon SY, Walters ET, Dougherty PM. Induction of monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR2 in primary sensory neurons contributes to paclitaxel-induced peripheral neuropathy. J Pain. 2013 Oct; 14(10):1031-44. PMID: 23726937.
      Citations: 56     Fields:    Translation:AnimalsCells
    60. Vichaya EG, Wang XS, Boyette-Davis JA, Mendoza TR, He Z, Thomas SK, Shah N, Williams LA, Cleeland CS, Dougherty PM. Subclinical pretreatment sensory deficits appear to predict the development of pain and numbness in patients with multiple myeloma undergoing chemotherapy. Cancer Chemother Pharmacol. 2013 Jun; 71(6):1531-40. PMID: 23543296.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    61. Yoon SY, Robinson CR, Zhang H, Dougherty PM. Spinal astrocyte gap junctions contribute to oxaliplatin-induced mechanical hypersensitivity. J Pain. 2013 Feb; 14(2):205-14. PMID: 23374942.
      Citations: 38     Fields:    Translation:AnimalsCells
    62. Boyette-Davis JA, Cata JP, Driver LC, Novy DM, Bruel BM, Mooring DL, Wendelschafer-Crabb G, Kennedy WR, Dougherty PM. Persistent chemoneuropathy in patients receiving the plant alkaloids paclitaxel and vincristine. Cancer Chemother Pharmacol. 2013 Mar; 71(3):619-26. PMID: 23228992.
      Citations: 47     Fields:    Translation:HumansCells
    63. Yoon SY, Patel D, Dougherty PM. Minocycline blocks lipopolysaccharide induced hyperalgesia by suppression of microglia but not astrocytes. Neuroscience. 2012 Sep 27; 221:214-24. PMID: 22742905.
      Citations: 29     Fields:    Translation:AnimalsCells
    64. Boyette-Davis JA, Eng C, Wang XS, Cleeland CS, Wendelschafer-Crabb G, Kennedy WR, Simone DA, Zhang H, Dougherty PM. Subclinical peripheral neuropathy is a common finding in colorectal cancer patients prior to chemotherapy. Clin Cancer Res. 2012 Jun 01; 18(11):3180-7. PMID: 22496202.
      Citations: 15     Fields:    Translation:Humans
    65. Rosellini W, Casavant R, Engineer N, Beall P, Pierce D, Jain R, Dougherty PM. Wireless peripheral nerve stimulation increases pain threshold in two neuropathic rat models. Exp Neurol. 2012 Jun; 235(2):621-6. PMID: 22487199.
      Citations: 2     Fields:    Translation:Animals
    66. Dougherty PM. Two pains at once: how can you tell which is worse? Neurosci Lett. 2012 Apr 04; 513(2):112-3. PMID: 22326928.
      Citations:    Fields:    Translation:Animals
    67. Zhang H, Yoon SY, Zhang H, Dougherty PM. Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of Paclitaxel-induced painful neuropathy. J Pain. 2012 Mar; 13(3):293-303. PMID: 22285612.
      Citations: 77     Fields:    Translation:AnimalsCells
    68. Zhang H, Dougherty PM. Acute inhibition of signalling phenotype of spinal GABAergic neurons by tumour necrosis factor-alpha. J Physiol. 2011 Sep 15; 589(Pt 18):4511-26. PMID: 21788348.
      Citations: 13     Fields:    Translation:AnimalsCells
    69. Boyette-Davis JA, Cata JP, Zhang H, Driver LC, Wendelschafer-Crabb G, Kennedy WR, Dougherty PM. Follow-up psychophysical studies in bortezomib-related chemoneuropathy patients. J Pain. 2011 Sep; 12(9):1017-24. PMID: 21703938.
      Citations: 34     Fields:    Translation:Humans
    70. Gupta SC, Kim JH, Kannappan R, Reuter S, Dougherty PM, Aggarwal BB. Role of nuclear factor ?B-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents. Exp Biol Med (Maywood). 2011 Jun 01; 236(6):658-71. PMID: 21565893.
      Citations: 30     Fields:    Translation:HumansCells
    71. Boyette-Davis J, Dougherty PM. Protection against oxaliplatin-induced mechanical hyperalgesia and intraepidermal nerve fiber loss by minocycline. Exp Neurol. 2011 Jun; 229(2):353-7. PMID: 21385581.
      Citations: 43     Fields:    Translation:AnimalsCells
    72. Boyette-Davis J, Xin W, Zhang H, Dougherty PM. Intraepidermal nerve fiber loss corresponds to the development of taxol-induced hyperalgesia and can be prevented by treatment with minocycline. Pain. 2011 Feb; 152(2):308-313. PMID: 21145656.
      Citations: 77     Fields:    Translation:AnimalsCells
    73. Zhang H, Nei H, Dougherty PM. A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-alpha. J Neurosci. 2010 Sep 22; 30(38):12844-55. PMID: 20861388.
      Citations: 41     Fields:    Translation:AnimalsCells
    74. Melisi D, Ossovskaya V, Zhu C, Rosa R, Ling J, Dougherty PM, Sherman BM, Abbruzzese JL, Chiao PJ. Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity. Clin Cancer Res. 2009 Oct 15; 15(20):6367-77. PMID: 19808866.
      Citations: 15     Fields:    Translation:AnimalsCells
    75. Gashev AA, Davis MJ, Gasheva OY, Nepiushchikh ZV, Wang W, Dougherty P, Kelly KA, Cai S, Von Der Weid PY, Muthuchamy M, Meininger CJ, Zawieja DC. Methods for lymphatic vessel culture and gene transfection. Microcirculation. 2009 Oct; 16(7):615-28. PMID: 19626551.
      Citations: 25     Fields:    Translation:AnimalsCells
    76. Zhang H, Xin W, Dougherty PM. Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes. Mol Pain. 2009 Jul 01; 5:36. PMID: 19570219.
      Citations: 18     Fields:    Translation:AnimalsCells
    77. Xin WJ, Weng HR, Dougherty PM. Plasticity in expression of the glutamate transporters GLT-1 and GLAST in spinal dorsal horn glial cells following partial sciatic nerve ligation. Mol Pain. 2009 Mar 26; 5:15. PMID: 19323820.
      Citations: 41     Fields:    Translation:AnimalsCells
    78. Cata JP, Weng HR, Dougherty PM. Behavioral and electrophysiological studies in rats with cisplatin-induced chemoneuropathy. Brain Res. 2008 Sep 16; 1230:91-8. PMID: 18657527.
      Citations: 29     Fields:    Translation:AnimalsCells
    79. Cata JP, Weng HR, Dougherty PM. The effects of thalidomide and minocycline on taxol-induced hyperalgesia in rats. Brain Res. 2008 Sep 10; 1229:100-10. PMID: 18652810.
      Citations: 46     Fields:    Translation:Animals
    80. Cata JP, Weng HR, Dougherty PM. Spinal injection of IL-2 or IL-15 alters mechanical and thermal withdrawal thresholds in rats. Neurosci Lett. 2008 May 23; 437(1):45-9. PMID: 18423867.
      Citations: 5     Fields:    Translation:Animals
    81. Garcia JM, Cata JP, Dougherty PM, Smith RG. Ghrelin prevents cisplatin-induced mechanical hyperalgesia and cachexia. Endocrinology. 2008 Feb; 149(2):455-60. PMID: 17962345.
      Citations: 37     Fields:    Translation:Animals
    82. Dougherty PM, Cata JP, Burton AW, Vu K, Weng HR. Dysfunction in multiple primary afferent fiber subtypes revealed by quantitative sensory testing in patients with chronic vincristine-induced pain. J Pain Symptom Manage. 2007 Feb; 33(2):166-79. PMID: 17280922.
      Citations: 40     Fields:    Translation:Humans
    83. Lee JI, Verhagen Metman L, Ohara S, Dougherty PM, Kim JH, Lenz FA. Internal pallidal neuronal activity during mild drug-related dyskinesias in Parkinson's disease: decreased firing rates and altered firing patterns. J Neurophysiol. 2007 Apr; 97(4):2627-41. PMID: 17215512.
      Citations: 13     Fields:    Translation:HumansCells
    84. Cata JP, Weng HR, Burton AW, Villareal H, Giralt S, Dougherty PM. Quantitative sensory findings in patients with bortezomib-induced pain. J Pain. 2007 Apr; 8(4):296-306. PMID: 17175202.
      Citations: 45     Fields:    Translation:Humans
    85. Aravindan N, Cata JP, Hoffman L, Dougherty PM, Riedel BJ, Price KJ, Shaw AD. Effects of isoflurane, pentobarbital, and urethane on apoptosis and apoptotic signal transduction in rat kidney. Acta Anaesthesiol Scand. 2006 Nov; 50(10):1229-37. PMID: 16978161.
      Citations: 10     Fields:    Translation:AnimalsCells
    86. Cata JP, Weng HR, Lee BN, Reuben JM, Dougherty PM. Clinical and experimental findings in humans and animals with chemotherapy-induced peripheral neuropathy. Minerva Anestesiol. 2006 Mar; 72(3):151-69. PMID: 16493391.
      Citations: 70     Fields:    Translation:HumansAnimals
    87. Aravindan N, Cata JP, Dougherty PM, Shaw AD. Effect of fenoldopam on ischemia/reperfusion-induced apoptosis. Ren Fail. 2006; 28(4):337-44. PMID: 16771250.
      Citations: 7     Fields:    Translation:AnimalsCells
    88. Cata JP, Weng HR, Chen JH, Dougherty PM. Altered discharges of spinal wide dynamic range neurons and down-regulation of glutamate transporter expression in rats with paclitaxel-induced hyperalgesia. Neuroscience. 2006; 138(1):329-38. PMID: 16361064.
      Citations: 40     Fields:    Translation:AnimalsCells
    89. Patel S, Ohara S, Dougherty PM, Gracely RH, Lenz FA. Psychophysical elements of place and modality specificity in the thalamic somatic sensory nucleus (ventral caudal, vc) of awake humans. J Neurophysiol. 2006 Feb; 95(2):646-59. PMID: 16192330.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    90. Weng HR, Aravindan N, Cata JP, Chen JH, Shaw AD, Dougherty PM. Spinal glial glutamate transporters downregulate in rats with taxol-induced hyperalgesia. Neurosci Lett. 2005 Sep 23; 386(1):18-22. PMID: 15975716.
      Citations: 41     Fields:    Translation:AnimalsCells
    91. Lee JI, Ohara S, Dougherty PM, Lenz FA. Pain and temperature encoding in the human thalamic somatic sensory nucleus (Ventral caudal): inhibition-related bursting evoked by somatic stimuli. J Neurophysiol. 2005 Sep; 94(3):1676-87. PMID: 15901758.
      Citations: 20     Fields:    Translation:HumansCells
    92. Korzick DH, Muller-Delp JM, Dougherty P, Heaps CL, Bowles DK, Krick KK. Exaggerated coronary vasoreactivity to endothelin-1 in aged rats: role of protein kinase C. Cardiovasc Res. 2005 May 01; 66(2):384-92. PMID: 15820207.
      Citations: 7     Fields:    Translation:Animals
    93. Weng HR, Dougherty PM. Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats. Neuroscience. 2005; 132(3):823-31. PMID: 15837142.
      Citations: 8     Fields:    Translation:AnimalsCells
    94. Lenz FA, Ohara S, Gracely RH, Dougherty PM, Patel SH. Pain encoding in the human forebrain: binary and analog exteroceptive channels. J Neurosci. 2004 Jul 21; 24(29):6540-4. PMID: 15269265.
      Citations: 6     Fields:    Translation:Humans
    95. Cata JP, Weng HR, Dougherty PM. Cyclooxygenase inhibitors and thalidomide ameliorate vincristine-induced hyperalgesia in rats. Cancer Chemother Pharmacol. 2004 Nov; 54(5):391-7. PMID: 15235822.
      Citations: 7     Fields:    Translation:Animals
    96. Dougherty PM, Cata JP, Cordella JV, Burton A, Weng HR. Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients. Pain. 2004 May; 109(1-2):132-42. PMID: 15082135.
      Citations: 128     Fields:    Translation:HumansCells
    97. Chen JH, Weng HR, Dougherty PM. Sensitization of dorsal root reflexes in vitro and hyperalgesia in neonatal rats produced by capsaicin. Neuroscience. 2004; 126(3):743-51. PMID: 15183522.
      Citations: 2     Fields:    Translation:Animals
    98. Cata JP, Cordella JV, Burton AW, Hassenbusch SJ, Weng HR, Dougherty PM. Spinal cord stimulation relieves chemotherapy-induced pain: a clinical case report. J Pain Symptom Manage. 2004 Jan; 27(1):72-8. PMID: 14711471.
      Citations: 14     Fields:    Translation:Humans
    99. Lee BN, Dantzer R, Langley KE, Bennett GJ, Dougherty PM, Dunn AJ, Meyers CA, Miller AH, Payne R, Reuben JM, Wang XS, Cleeland CS. A cytokine-based neuroimmunologic mechanism of cancer-related symptoms. Neuroimmunomodulation. 2004; 11(5):279-92. PMID: 15316238.
      Citations: 87     Fields:    Translation:Humans
    100. Cleeland CS, Bennett GJ, Dantzer R, Dougherty PM, Dunn AJ, Meyers CA, Miller AH, Payne R, Reuben JM, Wang XS, Lee BN. Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms. Cancer. 2003 Jun 01; 97(11):2919-25. PMID: 12767108.
      Citations: 153     Fields:    Translation:HumansAnimals
    101. Weng HR, Cordella JV, Dougherty PM. Changes in sensory processing in the spinal dorsal horn accompany vincristine-induced hyperalgesia and allodynia. Pain. 2003 May; 103(1-2):131-8. PMID: 12749967.
      Citations: 47     Fields:    Translation:AnimalsCells
    102. Weng HR, Lenz FA, Vierck C, Dougherty PM. Physiological changes in primate somatosensory thalamus induced by deafferentation are dependent on the spinal funiculi that are sectioned and time following injury. Neuroscience. 2003; 116(4):1149-60. PMID: 12617956.
      Citations: 14     Fields:    Translation:AnimalsCells
    103. Grabow TS, Dougherty PM. Gabapentin produces dose-dependent antinociception in the orofacial formalin test in the rat. Reg Anesth Pain Med. 2002 May-Jun; 27(3):277-83. PMID: 12016601.
      Citations: 4     Fields:    Translation:Animals
    104. Weng HR, Dougherty PM. Tuning of membrane properties regulates subliminal synapses in dorsal horn neurons of intact rats. Exp Neurol. 2002 May; 175(1):209-15. PMID: 12009773.
      Citations: 5     Fields:    Translation:AnimalsCells
    105. Grabow TS, Dougherty PM. Cervicomedullary intrathecal injection of morphine produces antinociception in the orofacial formalin test in the rat. Anesthesiology. 2001 Dec; 95(6):1427-34. PMID: 11748402.
      Citations: 5     Fields:    Translation:Animals
    106. Weng HR, Mansikka H, Winchurch R, Raja SN, Dougherty PM. Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice. Anesthesiology. 2001 Jun; 94(6):1105-12. PMID: 11465604.
      Citations: 8     Fields:    Translation:AnimalsCells
    107. Kirkpatrick AF, Herndon MP. Intrathecal morphine in chronic pain management. Anesthesiology. 2000 Dec; 93(6):1553-4. PMID: 11149462.
      Citations:    Fields:    Translation:Humans
    108. Raja SN, Dougherty PM. Reversing tissue injury-induced plastic changes in the spinal cord: the search for the magic bullet. Reg Anesth Pain Med. 2000 Sep-Oct; 25(5):441-4. PMID: 11009226.
      Citations: 1     Fields:    Translation:Humans
    109. LaBuda CJ, Cutler TD, Dougherty PM, Fuchs PN. Mechanical and thermal hypersensitivity develops following kainate lesion of the ventral posterior lateral thalamus in rats. Neurosci Lett. 2000 Aug 18; 290(1):79-83. PMID: 10925179.
      Citations: 8     Fields:    Translation:AnimalsCells
    110. Lenz FA, Lee JI, Garonzik IM, Rowland LH, Dougherty PM, Hua SE. Plasticity of pain-related neuronal activity in the human thalamus. Prog Brain Res. 2000; 129:259-73. PMID: 11098695.
      Citations: 4     Fields:    Translation:HumansAnimals
    111. Weng HR, Lee JI, Lenz FA, Schwartz A, Vierck C, Rowland L, Dougherty PM. Functional plasticity in primate somatosensory thalamus following chronic lesion of the ventral lateral spinal cord. Neuroscience. 2000; 101(2):393-401. PMID: 11074162.
      Citations: 17     Fields:    Translation:AnimalsCells
    112. Dougherty PM, Staats PS. Intrathecal drug therapy for chronic pain: from basic science to clinical practice. Anesthesiology. 1999 Dec; 91(6):1891-918. PMID: 10598634.
      Citations: 10     Fields:    Translation:HumansAnimals
    113. Lee J, Dougherty PM, Antezana D, Lenz FA. Responses of neurons in the region of human thalamic principal somatic sensory nucleus to mechanical and thermal stimuli graded into the painful range. J Comp Neurol. 1999 Aug 09; 410(4):541-55. PMID: 10398047.
      Citations: 15     Fields:    Translation:HumansCells
    114. Lee JI, Hua S, Clatterbuck RE, Moriarity J, Dougherty PM, Lenz FA. Ablative surgery and deep brain stimulation for Parkinson's disease. Neurosurgery. 1999 Aug; 45(2):417-8. PMID: 10449092.
      Citations:    Fields:    Translation:Humans
    115. Zirh A, Reich SG, Dougherty PM, Lenz FA. Stereotactic thalamotomy in the treatment of essential tremor of the upper extremity: reassessment including a blinded measure of outcome. J Neurol Neurosurg Psychiatry. 1999 Jun; 66(6):772-5. PMID: 10329753.
      Citations: 13     Fields:    Translation:Humans
    116. Lemstra AW, Verhagen Metman L, Lee JI, Dougherty PM, Lenz FA. Tremor-frequency (3-6 Hz) activity in the sensorimotor arm representation of the internal segment of the globus pallidus in patients with Parkinson's disease. Neurosci Lett. 1999 May 28; 267(2):129-32. PMID: 10400229.
      Citations: 10     Fields:    Translation:HumansCells
    117. Dougherty PM, Schwartz A, Lenz FA. Responses of primate spinomesencephalic tract cells to intradermal capsaicin. Neuroscience. 1999; 90(4):1377-92. PMID: 10338305.
      Citations: 1     Fields:    Translation:AnimalsCells
    118. Zhang ZH, Dougherty PM, Oppenheimer SM. Monkey insular cortex neurons respond to baroreceptive and somatosensory convergent inputs. Neuroscience. 1999; 94(2):351-60. PMID: 10579199.
      Citations: 23     Fields:    Translation:AnimalsCells
    119. Lenz FA, Suarez JI, Metman LV, Reich SG, Karp BI, Hallett M, Rowland LH, Dougherty PM. Pallidal activity during dystonia: somatosensory reorganisation and changes with severity. J Neurol Neurosurg Psychiatry. 1998 Nov; 65(5):767-70. PMID: 9810954.
      Citations: 32     Fields:    Translation:Humans
    120. Lenz FA, Garonzik IM, Zirh TA, Dougherty PM. Neuronal activity in the region of the thalamic principal sensory nucleus (ventralis caudalis) in patients with pain following amputations. Neuroscience. 1998 Oct; 86(4):1065-81. PMID: 9697114.
      Citations: 24     Fields:    Translation:HumansCellsCTClinical Trials
    121. Lenz FA, Gracely RH, Baker FH, Richardson RT, Dougherty PM. Reorganization of sensory modalities evoked by microstimulation in region of the thalamic principal sensory nucleus in patients with pain due to nervous system injury. J Comp Neurol. 1998 Sep 14; 399(1):125-38. PMID: 9725706.
      Citations: 9     Fields:    Translation:Humans
    122. Dougherty MP, Willis DW, Lenz AF. Transient inhibition of responses to thermal stimuli of spinal sensory tract neurons in monkeys during sensitization by intradermal capsaicin. Pain. 1998 Aug; 77(2):129-136. PMID: 9766830.
      Citations: 3     Fields:    Translation:AnimalsCells
    123. Zhang ZH, Dougherty PM, Oppenheimer SM. Characterization of baroreceptor-related neurons in the monkey insular cortex. Brain Res. 1998 Jun 15; 796(1-2):303-6. PMID: 9689483.
      Citations: 15     Fields:    Translation:AnimalsCells
    124. Oppenheimer SM, Kulshreshtha N, Lenz FA, Zhang Z, Rowland LH, Dougherty PM. Distribution of cardiovascular related cells within the human thalamus. Clin Auton Res. 1998 Jun; 8(3):173-9. PMID: 9651667.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    125. Dougherty PM, Mittman S, Lenz FA. Facilitation of responses to AMPA but not kainate by cyclothiazide in primate somatosensory thalamus. Neurosci Lett. 1998 Apr 17; 246(1):17-20. PMID: 9622197.
      Citations:    Fields:    Translation:Animals
    126. Lenz FA, Dougherty PM. Neurons in the human thalamic somatosensory nucleus (Ventralis caudalis) respond to innocuous cool and mechanical stimuli. J Neurophysiol. 1998 Apr; 79(4):2227-30. PMID: 9535983.
      Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
    127. Zirh TA, Lenz FA, Reich SG, Dougherty PM. Patterns of bursting occurring in thalamic cells during parkinsonian tremor. Neuroscience. 1998 Mar; 83(1):107-21. PMID: 9466402.
      Citations: 32     Fields:    Translation:HumansCellsCTClinical Trials
    128. Hua SE, Lenz FA, Zirh TA, Reich SG, Dougherty PM. Thalamic neuronal activity correlated with essential tremor. J Neurol Neurosurg Psychiatry. 1998 Feb; 64(2):273-6. PMID: 9489548.
      Citations: 22     Fields:    Translation:Humans
    129. Hua S, Reich SG, Zirh AT, Perry V, Dougherty PM, Lenz FA. The role of the thalamus and basal ganglia in parkinsonian tremor. Mov Disord. 1998; 13 Suppl 3:40-2. PMID: 9827593.
      Citations: 3     Fields:    Translation:Animals
    130. Suarez JI, Metman LV, Reich SG, Dougherty PM, Hallett M, Lenz FA. Pallidotomy for hemiballismus: efficacy and characteristics of neuronal activity. Ann Neurol. 1997 Nov; 42(5):807-11. PMID: 9392582.
      Citations: 10     Fields:    Translation:HumansCells
    131. Lenz FA, Gracely RH, Zirh TA, Leopold DA, Rowland LH, Dougherty PM. Human thalamic nucleus mediating taste and multiple other sensations related to ingestive behavior. J Neurophysiol. 1997 Jun; 77(6):3406-9. PMID: 9212287.
      Citations:    Fields:    Translation:HumansCells
    132. Cameron AA, Cliffer KD, Dougherty PM, Garrison CJ, Willis WD, Carlton SM. Time course of degenerative and regenerative changes in the dorsal horn in a rat model of peripheral neuropathy. J Comp Neurol. 1997 Mar 17; 379(3):428-42. PMID: 9067834.
      Citations: 11     Fields:    Translation:Animals
    133. Dougherty PM, Li YJ, Lenz FA, Rowland L, Mittman S. Correlation of effects of general anesthetics on somatosensory neurons in the primate thalamus and cortical EEG power. J Neurophysiol. 1997 Mar; 77(3):1375-92. PMID: 9084604.
      Citations: 4     Fields:    Translation:AnimalsCells
    134. Mandir AS, Rowland LH, Dougherty PM, Lenz FA. Microelectrode recording and stimulation techniques during stereotactic procedures in the thalamus and pallidum. Adv Neurol. 1997; 74:159-65. PMID: 9348411.
      Citations: 3     Fields:    Translation:Humans
    135. Dougherty PM, Li YJ, Lenz FA, Rowland L, Mittman S. Evidence that excitatory amino acids mediate afferent input to the primate somatosensory thalamus. Brain Res. 1996 Jul 29; 728(2):267-73. PMID: 8864493.
      Citations: 3     Fields:    Translation:Animals
    136. Lenz FA, Dougherty PM, Traill TA. Thalamic mechanisms of chest pain in the absence of cardiac pathology. Heart. 1996 May; 75(5):429-30. PMID: 8665328.
      Citations: 3     Fields:    Translation:Humans
    137. Lenz FA, Gracely RH, Romanoski AJ, Hope EJ, Rowland LH, Dougherty PM. Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensions of previously experienced pain. Nat Med. 1995 Sep; 1(9):910-3. PMID: 7585216.
      Citations: 10     Fields:    Translation:Humans
    138. Dougherty PM, Palecek J, Palecková V, Willis WD. Infusion of substance P or neurokinin A by microdialysis alters responses of primate spinothalamic tract neurons to cutaneous stimuli and to iontophoretically released excitatory amino acids. Pain. 1995 Jun; 61(3):411-425. PMID: 7478684.
      Citations: 2     Fields:    Translation:AnimalsCells
    139. Lenz FA, Gracely RH, Rowland LH, Dougherty PM. A population of cells in the human thalamic principal sensory nucleus respond to painful mechanical stimuli. Neurosci Lett. 1994 Oct 10; 180(1):46-50. PMID: 7877759.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    140. Lenz FA, Gracely RH, Hope EJ, Baker FH, Rowland LH, Dougherty PM, Richardson RT. The sensation of angina can be evoked by stimulation of the human thalamus. Pain. 1994 Oct; 59(1):119-125. PMID: 7854792.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    141. Garrison CJ, Dougherty PM, Carlton SM. GFAP expression in lumbar spinal cord of naive and neuropathic rats treated with MK-801. Exp Neurol. 1994 Oct; 129(2):237-43. PMID: 7957738.
      Citations: 33     Fields:    Translation:AnimalsCells
    142. Dougherty PM, Palecek J, Palecková V, Willis WD. Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin. J Neurophysiol. 1994 Oct; 72(4):1464-75. PMID: 7823080.
      Citations: 15     Fields:    Translation:AnimalsCells
    143. Palecek J, Palecková V, Dougherty PM, Willis WD. The effect of trans-ACPD, a metabotropic excitatory amino acid receptor agonist, on the responses of primate spinothalamic tract neurons. Pain. 1994 Mar; 56(3):261-269. PMID: 8022620.
      Citations: 1     Fields:    Translation:AnimalsCells
    144. Palecek J, Palecková V, Dougherty PM, Willis WD. The effect of phorbol esters on the responses of primate spinothalamic neurons to mechanical and thermal stimuli. J Neurophysiol. 1994 Feb; 71(2):529-37. PMID: 8176422.
      Citations: 6     Fields:    Translation:AnimalsCells
    145. Cameron AA, Dougherty PM, Garrison CJ, Willis WD, Carlton SM. The endogenous lectin RL-29 is transynaptically induced in dorsal horn neurons following peripheral neuropathy in the rat. Brain Res. 1993 Aug 20; 620(1):64-71. PMID: 8402200.
      Citations: 2     Fields:    Translation:AnimalsCells
    146. Dougherty PM, Palecek J, Zorn S, Willis WD. Combined application of excitatory amino acids and substance P produces long-lasting changes in responses of primate spinothalamic tract neurons. Brain Res Brain Res Rev. 1993 May-Aug; 18(2):227-46. PMID: 7687919.
      Citations: 12     Fields:    Translation:AnimalsCells
    147. Garrison CJ, Dougherty PM, Carlton SM. Quantitative analysis of substance P and calcitonin gene-related peptide immunohistochemical staining in the dorsal horn of neuropathic MK-801-treated rats. Brain Res. 1993 Apr 02; 607(1-2):205-14. PMID: 7683239.
      Citations: 6     Fields:    Translation:Animals
    148. Coggeshall RE, Dougherty PM, Pover CM, Carlton SM. Is large myelinated fiber loss associated with hyperalgesia in a model of experimental peripheral neuropathy in the rat? Pain. 1993 Feb; 52(2):233-242. PMID: 8384361.
      Citations: 9     Fields:    Translation:AnimalsCells
    149. Dafny N, Dougherty PM. Noninvasive subthreshold auricular electrical stimulation reduces the severity of precipitated and abrupt opiate withdrawal. Brain Res Bull. 1993; 31(5):491-2. PMID: 8495373.
      Citations:    Fields:    Translation:Animals
    150. Palecek J, Dougherty PM, Kim SH, Palecková V, Lekan H, Chung JM, Carlton SM, Willis WD. Responses of spinothalamic tract neurons to mechanical and thermal stimuli in an experimental model of peripheral neuropathy in primates. J Neurophysiol. 1992 Dec; 68(6):1951-66. PMID: 1337100.
      Citations: 22     Fields:    Translation:Animals
    151. Dougherty P, Hannallah M. A potentially serious complication that resulted from improper use of the Univent tube. Anesthesiology. 1992 Oct; 77(4):835. PMID: 1416188.
      Citations:    Fields:    Translation:Humans
    152. Dougherty PM, Palecek J, Paleckova V, Sorkin LS, Willis WD. The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli. J Neurosci. 1992 Aug; 12(8):3025-41. PMID: 1353793.
      Citations: 37     Fields:    Translation:AnimalsCells
    153. Palecek J, Palecková V, Dougherty PM, Carlton SM, Willis WD. Responses of spinothalamic tract cells to mechanical and thermal stimulation of skin in rats with experimental peripheral neuropathy. J Neurophysiol. 1992 Jun; 67(6):1562-73. PMID: 1321241.
      Citations: 32     Fields:    Translation:AnimalsCells
    154. Dougherty PM, Willis WD. Enhanced responses of spinothalamic tract neurons to excitatory amino acids accompany capsaicin-induced sensitization in the monkey. J Neurosci. 1992 Mar; 12(3):883-94. PMID: 1545244.
      Citations: 24     Fields:    Translation:AnimalsCells
    155. Dougherty PM, Garrison CJ, Carlton SM. Differential influence of local anesthetic upon two models of experimentally induced peripheral mononeuropathy in the rat. Brain Res. 1992 Jan 20; 570(1-2):109-15. PMID: 1319790.
      Citations: 11     Fields:    Translation:Animals
    156. Westlund KN, Sun YC, Sluka KA, Dougherty PM, Sorkin LS, Willis WD. Neural changes in acute arthritis in monkeys. II. Increased glutamate immunoreactivity in the medial articular nerve. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):15-27. PMID: 1353392.
      Citations: 9     Fields:    Translation:AnimalsCells
    157. Sluka KA, Dougherty PM, Sorkin LS, Willis WD, Westlund KN. Neural changes in acute arthritis in monkeys. III. Changes in substance P, calcitonin gene-related peptide and glutamate in the dorsal horn of the spinal cord. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):29-38. PMID: 1379098.
      Citations: 15     Fields:    Translation:Animals
    158. Dougherty PM, Sluka KA, Sorkin LS, Westlund KN, Willis WD. Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):1-13. PMID: 1638273.
      Citations: 13     Fields:    Translation:Animals
    159. Sorkin LS, Westlund KN, Sluka KA, Dougherty PM, Willis WD. Neural changes in acute arthritis in monkeys. IV. Time-course of amino acid release into the lumbar dorsal horn. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):39-50. PMID: 1638274.
      Citations: 17     Fields:    Translation:Animals
    160. Garrison CJ, Dougherty PM, Kajander KC, Carlton SM. Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury. Brain Res. 1991 Nov 22; 565(1):1-7. PMID: 1723019.
      Citations: 99     Fields:    Translation:AnimalsCells
    161. Cameron AA, Cliffer KD, Dougherty PM, Willis WD, Carlton SM. Changes in lectin, GAP-43 and neuropeptide staining in the rat superficial dorsal horn following experimental peripheral neuropathy. Neurosci Lett. 1991 Oct 14; 131(2):249-52. PMID: 1722299.
      Citations: 6     Fields:    Translation:Animals
    162. Dougherty PM, Willis WD. Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of N-methyl-D-aspartic acid and substance P. Pain. 1991 Oct; 47(1):85-93. PMID: 1722895.
      Citations: 22     Fields:    Translation:Animals
    163. Carlton SM, Dougherty PM, Pover CM, Coggeshall RE. Neuroma formation and numbers of axons in a rat model of experimental peripheral neuropathy. Neurosci Lett. 1991 Sep 30; 131(1):88-92. PMID: 1791984.
      Citations: 15     Fields:    Translation:AnimalsCells
    164. Dougherty PM, Willis WD. Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist. Brain Res. 1991 Feb 22; 542(1):15-22. PMID: 1675920.
      Citations: 4     Fields:    Translation:AnimalsCells
    165. Dougherty PM, Dafny N. Microiontophoretic application of muramyl-dipeptide upon single cortical, hippocampal and hypothalamic neurons in rats. Neuropharmacology. 1990 Nov; 29(11):973-81. PMID: 1982342.
      Citations: 1     Fields:    Translation:AnimalsCells
    166. Dougherty PM, Dafny N. Muramyl-dipeptide, a macrophage-derived cytokine, alters neuronal activity in hypothalamus and hippocampus but not in the dorsal raphe/periaqueductal gray of rats. J Neuroimmunol. 1990 Aug; 28(3):201-8. PMID: 2373761.
      Citations: 1     Fields:    Translation:Animals
    167. Dougherty PM, Qiao JT, Wiggins RC, Dafny N. Microiontophoresis of cocaine, desipramine, sulpiride, methysergide, and naloxone in habenula and parafasciculus. Exp Neurol. 1990 Jun; 108(3):241-6. PMID: 2351212.
      Citations: 5     Fields:    Translation:AnimalsCells
    168. Qiao JT, Dougherty PM, Wiggins RC, Dafny N. Effects of microiontophoretic application of cocaine, alone and with receptor antagonists, upon the neurons of the medial prefrontal cortex, nucleus accumbens and caudate nucleus of rats. Neuropharmacology. 1990 Apr; 29(4):379-85. PMID: 2342637.
      Citations: 3     Fields:    Translation:AnimalsCells
    169. Dougherty PM, Dong WQ, Faillace LA, Dafny N. Trans-cranial electrical stimulation attenuates abrupt morphine withdrawal in rats assayed by remote computerized quantification of multiple motor behavior indices. Eur J Pharmacol. 1990 Jan 10; 175(2):187-95. PMID: 2311653.
      Citations: 2     Fields:    Translation:Animals
    170. Dougherty PM, Qiao JT, Wiggins RC, Dafny N. Cocaine interaction with sulpiride, methysergide, naloxone and desipramine: neurophysiological effects of mesolimbic and neostriatal neuronal activity. NIDA Res Monogr. 1990; 105:612-4. PMID: 1876144.
      Citations:    Fields:    Translation:AnimalsCells
    171. Dougherty PM, Pellis NR, Dafny N. The brain and the immune system: an intact immune system is essential for the manifestation of withdrawal in opiate addicted rats. Neuroscience. 1990; 36(2):285-9. PMID: 2215925.
      Citations: 7     Fields:    Translation:Animals
    172. Dafny N, Dougherty PM, Drath D. Immunosuppressive agent modulates the severity of opiate withdrawal. NIDA Res Monogr. 1990; 105:553-5. PMID: 1876116.
      Citations: 2     Fields:    Translation:Animals
    173. Dafny N, Dougherty PM, Pellis NR. The immune system and opiate withdrawal. Int J Immunopharmacol. 1989; 11(4):371-5. PMID: 2674032.
      Citations: 4     Fields:    Translation:Animals
    174. Dafny N, Dougherty PM, Pellis NR. The immune system and morphine dependence. NIDA Res Monogr. 1989; 95:293-5. PMID: 2640972.
      Citations:    Fields:    Translation:AnimalsCells
    175. Dougherty PM, Dafny N. Trans-cranial electrical stimulation attenuates the severity of naloxone-precipitated morphine withdrawal in rats. Life Sci. 1989; 44(26):2051-6. PMID: 2747416.
      Citations:    Fields:    Translation:Animals
    176. Dougherty PM, Dafny N. Cyclosporine affects central nervous system opioid activity via direct and indirect means. Brain Behav Immun. 1988 Sep; 2(3):242-53. PMID: 3242657.
      Citations: 4     Fields:    Translation:Animals
    177. Dafny N, Lee JR, Dougherty PM. Immune response products alter CNS activity: interferon modulates central opioid functions. J Neurosci Res. 1988; 19(1):130-9. PMID: 2449543.
      Citations: 7     Fields:    Translation:Animals
    178. Dougherty PM, Dafny N. Neuroimmune intercommunication, central opioids, and the immune response to bacterial endotoxin. J Neurosci Res. 1988; 19(1):140-8. PMID: 3343705.
      Citations:    Fields:    Translation:Animals
    179. Dougherty PM, Pearl J, Krajewski KJ, Pellis NR, Dafny N. Differential modification of morphine and methadone dependence by interferon alpha. Neuropharmacology. 1987 Nov; 26(11):1595-600. PMID: 3431662.
      Citations:    Fields:    Translation:Animals
    180. Dougherty PM, Dafny N. Irradiation exposure modulates central opioid functions. Exp Neurol. 1987 Nov; 98(2):301-16. PMID: 3666080.
      Citations:    Fields:    Translation:AnimalsCells
    181. Dougherty PM, Drath DB, Dafny N. Evidence of an immune system to brain communication axis that affects central opioid functions: muramyl peptides attenuate opiate withdrawal. Eur J Pharmacol. 1987 Sep 11; 141(2):253-60. PMID: 2824218.
      Citations: 1     Fields:    Translation:AnimalsCells
    182. Pellis NR, Kletzly NE, Dougherty PM, Aronowski J, Dafny N. Participation of lymphoid cells in the withdrawal syndrome of opiate dependent rats. Life Sci. 1987 Apr 20; 40(16):1589-93. PMID: 3550348.
      Citations: 1     Fields:    Translation:AnimalsCells
    183. Dougherty PM, Aronowski J, Drath D, Dafny N. Evidence of neuro-immunologic interactions: cyclosporine modifies opiate withdrawal by effects on the brain and immune components. J Neuroimmunol. 1987 Jan; 13(3):331-42. PMID: 3793881.
      Citations: 2     Fields:    Translation:Animals
    184. Dougherty PM, Harper C, Dafny N. The effect of alpha-interferon, cyclosporine A, and radiation-induced immune suppression on morphine-induced hypothermia and tolerance. Life Sci. 1986 Dec 08; 39(23):2191-7. PMID: 3784774.
      Citations: 1     Fields:    Translation:Animals
    185. Dougherty PM, Aronowski J, Samorajski T, Dafny N. Opiate antinociception is altered by immunemodification: the effect of interferon, cyclosporine and radiation-induced immune suppression upon acute and long-term morphine activity. Brain Res. 1986 Oct 22; 385(2):401-4. PMID: 3779401.
      Citations:    Fields:    Translation:Animals
    186. CD8+ T cells and endogenous IL-10 are required for resolution of chemotherapy-induced neuropathic pain. Journal of Neuroscience. 36:11074-11083.
    187. Relationship of membrane properties, spike burst responses, laminar location, and functional class of dorsal horn neurons recorded in vitro. Journal of Neurophysiology. 116:1137-1151.
    188. Cocaine interaction with sulpiride, methysergide, naloxone and desipramine. 612-614.
    189. Anatomy and physiology of somatosensory and pain processing. 1-7.
    190. Does sensitization of responses to excitatory amino acids underlie the psychophysical reports of two modalities of increased sensitivity in zones of secondary hyperalgesia?. APS Journal. 2:276-279.
    191. MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy. Brain, Behavior, and Immunity.
    192. A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-α (The Journal of Neuroscience (2010) (12844-12855)). Journal of Neuroscience. 31.
    193. Central sensitization and cutaneous hyperalgesia. Seminars in Pain Medicine. 1:121-131.
    194. Hyperalgesia and amino acids. Receptor selectivity based on stimulus intensity and a role for peptides. APS Journal. 3:240-248.
    195. Measuring Therapy-Induced Peripheral Neuropathy. Journal of Pain. 16:1032-1043.
    196. Neurochemistry of Somatosensory and Pain Processing. 7-14.
    197. Hemispatial somatosensory and motor extinction after stereotactic thalamic lesions. Neurocase. 4:21-33.
    198. Long-lasting enhancement of excitability of spinothalamic tract neurones following combined application of excitatory amino acids and substance P in anaesthetized macaques. Journal of Physiology. 425.
    199. The sensory-limbic model of pain memory. Pain Forum. 6:22-43.
    200. A new version of the thalamic disinhibition hypothesis of central pain. Pain Forum. 7:1-28.
    201. Managing chemotherapy-induced neuropathy. Journal of Supportive Oncology. 6:70.
    202. Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy. Journal of Pain. 17:775-786.
    203. Is Chemotherapy-induced Peripheral Neuropathy More Than Just a Peripheral Nervous System Disorder?. Anesthesiology.
    204. Prechemotherapy Touch Sensation Deficits Predict Oxaliplatin-Induced Neuropathy in Patients with Colorectal Cancer. Oncology (Switzerland).
    205. Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Supportive Care in Cancer. 1-10.
    206. Higher Stem Cell Dose Infusion after Intensive Chemotherapy Does Not Improve Symptom Burden in Older Patients with Multiple Myeloma and Amyloidosis. Biology of Blood and Marrow Transplantation. 22:226-231.
    207. Mechanisms involved in the development of chemotherapy-induced neuropathy. Pain management. 5:285-296.
    208. Neurochemistry of somatosensory and pain processing. 8-15.
    209. Anatomy and Physiology of Somatosensory and Pain Processing. 1-6.
    210. Immunosuppressive agent modulates the severity of opiate withdrawal. 553-555.
    211. Mechanisms of chemotherapy-induced neuropathic pain.
    212. Reply to D. Nuytten and colleagues. Pain. 54:362-363.
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