TitleAssociate Professor
InstitutionMD Anderson
DepartmentGI Medical Oncology
Address1400 Holcombe Blvd
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Liu Y, Wei D, Deguchi Y, Xu W, Tian R, Liu F, Xu M, Mao F, Li D, Chen W, Valentin LA, Deguchi E, Yao JC, Shureiqi I, Zuo X. PPARd dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment. Gastric Cancer. 2023 Nov; 26(6):904-917. PMID: 37572185; PMCID: PMC10640489.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    2. Ghosh J, Schultz BM, Chan J, Wultsch C, Singh R, Shureiqi I, Chow S, Doymaz A, Varriano S, Driscoll M, Muse J, Kleiman FE, Krampis K, Issa JJ, Sapienza C. Epigenome-Wide Study Identifies Epigenetic Outliers in Normal Mucosa of Patients with Colorectal Cancer. Cancer Prev Res (Phila). 2022 11 01; 15(11):755-766. PMID: 36219239; PMCID: PMC9623234.
      Citations:    Fields:    Translation:HumansCells
    3. Davis JS, Chavez JC, Kok M, San Miguel Y, Lee HY, Henderson H, Overman MJ, Morris V, Kee B, Fogelman D, Advani SM, Johnson B, Parseghian C, Shen JP, Dasari A, Shaw KR, Vilar E, Raghav KP, Shureiqi I, Wolff RA, Meric-Bernstam F, Maru D, Menter DG, Kopetz S, Chang S. Association of Prediagnosis Obesity and Postdiagnosis Aspirin With Survival From Stage IV Colorectal Cancer. JAMA Netw Open. 2022 10 03; 5(10):e2236357. PMID: 36239938; PMCID: PMC9568800.
      Citations:    Fields:    Translation:Humans
    4. Shureiqi I. Aspirin for Colorectal Cancer Prevention: Age Matters. Cancer Prev Res (Phila). 2022 09 01; 15(9):565-567. PMID: 36047054.
    5. Liu Y, Deguchi Y, Wei D, Liu F, Moussalli MJ, Deguchi E, Li D, Wang H, Valentin LA, Colby JK, Wang J, Zheng X, Ying H, Gagea M, Ji B, Shi J, Yao JC, Zuo X, Shureiqi I. Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARd. Nat Commun. 2022 05 13; 13(1):2665. PMID: 35562376; PMCID: PMC9106716.
      Citations:    Fields:    Translation:HumansAnimals
    6. Yang P, Zuo X, Advani S, Wei B, Malek J, Day RS, Shureiqi I. Celecoxib Colorectal Bioavailability and Chemopreventive Response in Patients with Familial Adenomatous Polyposis. Cancer Prev Res (Phila). 2022 04 01; 15(4):217-223. PMID: 34610992; PMCID: PMC8980107.
      Citations:    Fields:    Translation:Humans
    7. Maertzdorf J, Zuo X, Shureiqi I, Mollenkopf HJ, Meyer TF, Kapalczynska M, Lin M, Heuberger J, Muellerke S, Vidal R, Fischer AS, Sauer S, Berger H, Kidess E, Tacke F, Sigal M. BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation. Nat Commun. 2022 03 24; 13(1):1577. PMID: 35332152; PMCID: PMC8948225.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Powell RT, Moussalli MJ, Guo L, Bae G, Singh P, Stephan C, Shureiqi I, Davies PJ. deepOrganoid: A brightfield cell viability model for screening matrix-embedded organoids. SLAS Discov. 2022 04; 27(3):175-184. PMID: 35314378.
      Citations:    Fields:    Translation:Humans
    9. Pudakalakatti S, Titus M, Ramachandran S, Zacharias NM, Shureiqi I, Liu Y, Yao JC, Zuo X, Bhattacharya PK, Enriquez JS. Identifying the Metabolic Signatures of PPARD-Overexpressing Gastric Tumors. Int J Mol Sci. 2022 Jan 31; 23(3). PMID: 35163565; PMCID: PMC8835946.
      Citations:    Fields:    Translation:AnimalsCells
    10. Cata JP, Lacagnina MJ, Li J, Gorur A, Agudelo-Jimenez R, Wei B, Hagberg CA, Dougherty PM, Shureiqi I, Yang P, Grace PM, Pati?o M. A rat model to investigate quality of recovery after abdominal surgery. Pain Rep. 2021 Jul-Aug; 6(2):e943. PMID: 34235345; PMCID: PMC8253582.
      Citations: 1     
    11. Leung M, Rogers JE, Shureiqi I. Use of Uridine Triacetate to Reverse Severe Persistent Myelosuppression Following 5-fluorouracil Exposure in a Patient With a c.557A>G Heterozygous DPYD Variant. Clin Colorectal Cancer. 2021 09; 20(3):273-278. PMID: 33965356.
      Citations:    Fields:    Translation:Humans
    12. Liu F, Zuo X, Liu Y, Deguchi Y, Moussalli MJ, Chen W, Yang P, Wei B, Tan L, Lorenzi PL, Gao S, Jaoude JC, Mehdizadeh A, Valentin LA, Wei D, Shureiqi I. Suppression of Membranous LRP5 Recycling, Wnt/?-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P. Cell Rep. 2020 08 18; 32(7):108049. PMID: 32814052; PMCID: PMC8765570.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    13. Kee B, Fogelman D, Dasari A, Shureiqi I, Raghav K, Morris V, Johnson B, Overman M, Wolff R, Kopetz S, Rogers J, Ahmed SU, Mehdizadeh A, Rothschild N, Eng C, J?come AA. FOLFOXIRI Versus Doublet Regimens in Right-Sided Metastatic Colorectal Cancer: Focus on Subsequent Therapies and Impact on Overall Survival. Clin Colorectal Cancer. 2020 12; 19(4):248-255.e6. PMID: 32665092.
      Citations:    Fields:    Translation:Humans
    14. Advani SM, Shi Q, Overman MJ, Loree JM, Lam M, Morris V, Shureiqi I, Kee B, Dasari A, Vilar E, Sarshekeh AM, Lin HK, Manuel S, Hamilton S, Raghav K, Maru D, Kopetz S, Wang XS. Patient-reported Symptom Outcomes and Microsatellite Instability in Patients With Metastatic Colorectal Cancer. Clin Colorectal Cancer. 2020 03; 19(1):48-56.e2. PMID: 32008976.
      Citations: 1     Fields:    Translation:HumansCells
    15. Korphaisarn K, Morris V, Davis JS, Overman MJ, Fogelman DR, Kee BK, Dasari A, Raghav KPS, Shureiqi I, Trupti M, Wolff RA, Eng C, Menter DG, Hamilton S, Kopetz S. Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma. Br J Cancer. 2019 09; 121(6):505-510. PMID: 31406299; PMCID: PMC6738104.
      Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
    16. Zuo X, Deguchi Y, Xu W, Liu Y, Li HS, Wei D, Tian R, Chen W, Xu M, Yang Y, Gao S, Jaoude JC, Liu F, Chrieki SP, Moussalli MJ, Gagea M, Sebastian MM, Zheng X, Tan D, Broaddus R, Wang J, Ajami NJ, Swennes AG, Watowich SS, Shureiqi I. PPARD and Interferon Gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice. Gastroenterology. 2019 07; 157(1):163-178. PMID: 30885780; PMCID: PMC6581611.
      Citations: 16     Fields:    Translation:AnimalsCells
    17. Liu Y, Deguchi Y, Tian R, Wei D, Wu L, Chen W, Xu W, Xu M, Liu F, Gao S, Jaoude JC, Chrieki SP, Moussalli MJ, Gagea M, Morris J, Broaddus RR, Zuo X, Shureiqi I. Pleiotropic Effects of PPARD Accelerate Colorectal Tumorigenesis, Progression, and Invasion. Cancer Res. 2019 03 01; 79(5):954-969. PMID: 30679176; PMCID: PMC6397663.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    18. Liu Y, Colby JK, Zuo X, Jaoude J, Wei D, Shureiqi I. The Role of PPAR-d in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor. Int J Mol Sci. 2018 Oct 26; 19(11). PMID: 30373124; PMCID: PMC6275063.
      Citations: 45     Fields:    Translation:HumansAnimals
    19. Wang L, Shureiqi I, Stroehlein JR, Wei D. Novel and emerging innate immune therapeutic targets for pancreatic cancer. Expert Opin Ther Targets. 2018 12; 22(12):977-981. PMID: 30332892.
      Citations: 2     Fields:    Translation:HumansAnimals
    20. Colby JK, Jaoude J, Liu F, Shureiqi I. Oxygenated lipid signaling in tumor-associated macrophages-focus on colon cancer. Cancer Metastasis Rev. 2018 09; 37(2-3):289-315. PMID: 29934822.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    21. Shureiqi I. Molecular Predicators of Duodenal Familial Adenomatous Polyposis Chemoprevention: Do Chemopreventive Drugs Hit Their Presumed Molecular Targets? Cancer Prev Res (Phila). 2018 01; 11(1):1-3. PMID: 29263155.
      Citations:    Fields:    Translation:Humans
    22. Pereira AAL, Morelli MP, Overman M, Kee B, Fogelman D, Vilar E, Shureiqi I, Raghav K, Eng C, Manuel S, Crosby S, Wolff RA, Banks K, Lanman R, Talasaz A, Kopetz S, Morris V. Clinical utility of circulating cell-free DNA in advanced colorectal cancer. PLoS One. 2017; 12(8):e0183949. PMID: 28850629; PMCID: PMC5574560.
      Citations: 12     Fields:    Translation:Humans
    23. Korphaisarn K, Morris VK, Overman MJ, Fogelman DR, Kee BK, Raghav KPS, Manuel S, Shureiqi I, Wolff RA, Eng C, Menter D, Hamilton SR, Kopetz S, Dasari A. FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma. Oncotarget. 2017 Jun 13; 8(24):39268-39279. PMID: 28424412; PMCID: PMC5503612.
      Citations: 32     Fields:    Translation:Humans
    24. Mehrvarz Sarshekeh A, Advani S, Overman MJ, Manyam G, Kee BK, Fogelman DR, Dasari A, Raghav K, Vilar E, Manuel S, Shureiqi I, Wolff RA, Patel KP, Luthra R, Shaw K, Eng C, Maru DM, Routbort MJ, Meric-Bernstam F, Kopetz S. Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer. PLoS One. 2017; 12(3):e0173345. PMID: 28267766; PMCID: PMC5340382.
      Citations: 40     Fields:    
    25. Tian R, Zuo X, Jaoude J, Mao F, Colby J, Shureiqi I. ALOX15 as a suppressor of inflammation and cancer: Lost in the link. Prostaglandins Other Lipid Mediat. 2017 09; 132:77-83. PMID: 28089732; PMCID: PMC5509529.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    26. Zuo X, Xu W, Xu M, Tian R, Moussalli MJ, Mao F, Zheng X, Wang J, Morris JS, Gagea M, Eng C, Kopetz S, Maru DM, Rashid A, Broaddus R, Wei D, Hung MC, Sood AK, Shureiqi I. Metastasis regulation by PPARD expression in cancer cells. JCI Insight. 2017 01 12; 2(1):e91419. PMID: 28097239; PMCID: PMC5214933.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    27. Wu Y, Fang B, Yang XQ, Wang L, Chen D, Krasnykh V, Carter BZ, Morris JS, Shureiqi I. Therapeutic Molecular Targetingof 15-Lipoxygenase-1 in Colon Cancer. Mol Ther. 2008 May; 16(5):886-892. PMID: 28178489.
      Citations: 1     Fields:    
    28. Hong DS, Morris VK, El Osta B, Sorokin AV, Janku F, Fu S, Overman MJ, Piha-Paul S, Subbiah V, Kee B, Tsimberidou AM, Fogelman D, Bellido J, Shureiqi I, Huang H, Atkins J, Tarcic G, Sommer N, Lanman R, Meric-Bernstam F, Kopetz S. Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation. Cancer Discov. 2016 12; 6(12):1352-1365. PMID: 27729313; PMCID: PMC5562357.
      Citations: 100     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    29. Overman MJ, Morris V, Kee B, Fogelman D, Xiao L, Eng C, Dasari A, Shroff R, Mazard T, Shaw K, Vilar E, Raghav K, Shureiqi I, Liang L, Mills GB, Wolff RA, Hamilton S, Meric-Bernstam F, Abbruzzese J, Morris J, Maru D, Kopetz S. Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials. Ann Oncol. 2016 06; 27(6):1068-1074. PMID: 27045102; PMCID: PMC6276928.
      Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
    30. Sak ME, Alanbay I, Rodriguez A, Gokaslan T, Borahay M, Shureiqi I, Kilic GS. The role of 15-lipoxygenase-1 expression and its potential role in the pathogenesis of endometrial hyperplasia and endometrial adenocarcinomas. Eur J Gynaecol Oncol. 2016; 37(1):36-40. PMID: 27048107.
      Citations: 2     Fields:    Translation:Humans
    31. Ford NA, Rossi EL, Barnett K, Yang P, Bowers LW, Hidaka BH, Kimler BF, Carlson SE, Shureiqi I, deGraffenried LA, Fabian CJ, Hursting SD. Omega-3-Acid Ethyl Esters Block the Protumorigenic Effects of Obesity in Mouse Models of Postmenopausal Basal-like and Claudin-Low Breast Cancer. Cancer Prev Res (Phila). 2015 Sep; 8(9):796-806. PMID: 26100521; PMCID: PMC5024781.
      Citations: 12     Fields:    Translation:AnimalsCells
    32. Reddy SM, Kopetz S, Morris J, Parikh N, Qiao W, Overman MJ, Fogelman D, Shureiqi I, Jacobs C, Malik Z, Jimenez CA, Wolff RA, Abbruzzese JL, Gallick G, Eng C. Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer. Invest New Drugs. 2015 Aug; 33(4):977-84. PMID: 26062928.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    33. Mao F, Xu M, Zuo X, Yu J, Xu W, Moussalli MJ, Elias E, Li HS, Watowich SS, Shureiqi I. 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway. FASEB J. 2015 Jun; 29(6):2359-70. PMID: 25713055; PMCID: PMC4447220.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    34. Bolonesi RM, Rogers JE, Shureiqi I. A case report--treatment of metastatic colorectal cancer in a patient on hemodialysis. J Gastrointest Cancer. 2014 Dec; 45 Suppl 1:161-5. PMID: 24756833.
      Citations: 1     Fields:    Translation:Humans
    35. Zuo X, Xu M, Yu J, Wu Y, Moussalli MJ, Manyam GC, Lee SI, Liang S, Gagea M, Morris JS, Broaddus RR, Shureiqi I. Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-d/? overexpression. J Natl Cancer Inst. 2014 Apr; 106(4):dju052. PMID: 24681603; PMCID: PMC3982893.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    36. Wu Y, Mao F, Zuo X, Moussalli MJ, Elias E, Xu W, Shureiqi I. 15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1a expression in human colon cancer cells. Cancer Med. 2014 Jun; 3(3):472-84. PMID: 24634093; PMCID: PMC4101738.
      Citations: 10     Fields:    Translation:HumansCells
    37. Tahara T, Yamamoto E, Suzuki H, Maruyama R, Chung W, Garriga J, Jelinek J, Yamano HO, Sugai T, An B, Shureiqi I, Toyota M, Kondo Y, Issa JP, Est?cio MR. Fusobacterium in colonic flora and molecular features of colorectal carcinoma. Cancer Res. 2014 Mar 01; 74(5):1311-8. PMID: 24385213; PMCID: PMC4396185.
      Citations: 189     Fields:    Translation:HumansCells
    38. Das P, Eng C, Rodriguez-Bigas MA, Chang GJ, Skibber JM, You YN, Maru DM, Munsell MF, Clemons MV, Kopetz SE, Garrett CR, Shureiqi I, Delclos ME, Krishnan S, Crane CH. Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial. Int J Radiat Oncol Biol Phys. 2014 Feb 01; 88(2):301-5. PMID: 24315563; PMCID: PMC5592790.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    39. Bailey AM, Zhan L, Maru D, Shureiqi I, Pickering CR, Kiriakova G, Izzo J, He N, Wei C, Baladandayuthapani V, Liang H, Kopetz S, Powis G, Guo GL. FXR silencing in human colon cancer by DNA methylation and KRAS signaling. Am J Physiol Gastrointest Liver Physiol. 2014 Jan 01; 306(1):G48-58. PMID: 24177031; PMCID: PMC3920083.
      Citations: 35     Fields:    Translation:HumansCells
    40. Ling H, Spizzo R, Atlasi Y, Nicoloso M, Shimizu M, Redis RS, Nishida N, Song J, Guo Z, Ivan C, Barbarotto E, De Vries I, Zhang X, Ferracin M, Churchman M, van Galen JF, Beverloo BH, Shariati M, Haderk F, Estecio MR, Garcia-Manero G, Patijn GA, Gotley DC, Bhardwaj V, Shureiqi I, Sen S, Multani AS, Welsh J, Yamamoto K, Taniguchi I, Song MA, Gallinger S, Casey G, Thibodeau SN, Tiirikainen M, Mani SA, Zhang W, Davuluri RV, Mimori K, Mori M, Sieuwerts AM, Martens JW, Tomlinson I, Negrini M, Berindan-Neagoe I, Foekens JA, Hamilton SR, Lanza G, Kopetz S, Fodde R, Calin GA, Gaf? R, Le Marchand L. CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res. 2013 Sep; 23(9):1446-61. PMID: 23796952; PMCID: PMC3759721.
      Citations: 314     Fields:    Translation:HumansAnimalsCells
    41. Lynch PM, Morris JS, Ross WA, Rodriguez-Bigas MA, Posadas J, Khalaf R, Weber DM, Sepeda VO, Levin B, Shureiqi I. Global quantitative assessment of the colorectal polyp burden in familial adenomatous polyposis by using a web-based tool. Gastrointest Endosc. 2013 Mar; 77(3):455-63. PMID: 23332604; PMCID: PMC3574220.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    42. Yang P, Cartwright C, Efuet E, Hamilton SR, Wistuba II, Menter D, Addington C, Shureiqi I, Newman RA. Cellular location and expression of Na+, K+ -ATPase a subunits affect the anti-proliferative activity of oleandrin. Mol Carcinog. 2014 Apr; 53(4):253-63. PMID: 23073998; PMCID: PMC4442617.
      Citations: 14     Fields:    Translation:HumansCells
    43. Xu M, Zuo X, Shureiqi I. Targeting peroxisome proliferator-activated receptor-?/d in colon cancer: how to aim? Biochem Pharmacol. 2013 Mar 01; 85(5):607-611. PMID: 23041232; PMCID: PMC3562563.
      Citations: 12     Fields:    Translation:Humans
    44. Zuo X, Shureiqi I. Eicosanoid profiling in colon cancer: emergence of a pattern. Prostaglandins Other Lipid Mediat. 2013 Jul-Aug; 104-105:139-43. PMID: 22960430; PMCID: PMC3532570.
      Citations: 12     Fields:    Translation:HumansCells
    45. Yang P, Cartwright CA, Li J, Wen S, Prokhorova IN, Shureiqi I, Troncoso P, Navone NM, Newman RA, Kim J. Arachidonic acid metabolism in human prostate cancer. Int J Oncol. 2012 Oct; 41(4):1495-503. PMID: 22895552; PMCID: PMC3982713.
      Citations: 24     Fields:    Translation:HumansCells
    46. Zuo X, Peng Z, Wu Y, Moussalli MJ, Yang XL, Wang Y, Parker-Thornburg J, Morris JS, Broaddus RR, Fischer SM, Shureiqi I. Effects of gut-targeted 15-LOX-1 transgene expression on colonic tumorigenesis in mice. J Natl Cancer Inst. 2012 May 02; 104(9):709-16. PMID: 22472308; PMCID: PMC3341308.
      Citations: 18     Fields:    Translation:AnimalsCells
    47. Il Lee S, Zuo X, Shureiqi I. 15-Lipoxygenase-1 as a tumor suppressor gene in colon cancer: is the verdict in? Cancer Metastasis Rev. 2011 Dec; 30(3-4):481-91. PMID: 22037943; PMCID: PMC3261081.
      Citations: 27     Fields:    Translation:HumansAnimals
    48. Moussalli MJ, Wu Y, Zuo X, Yang XL, Wistuba II, Raso MG, Morris JS, Bowser JL, Minna JD, Lotan R, Shureiqi I. Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion. Cancer Prev Res (Phila). 2011 Dec; 4(12):1961-72. PMID: 21881028; PMCID: PMC3232310.
      Citations: 17     Fields:    Translation:HumansCells
    49. Shureiqi I, Baron JA. Curcumin chemoprevention: the long road to clinical translation. Cancer Prev Res (Phila). 2011 Mar; 4(3):296-8. PMID: 21372027.
      Citations: 17     Fields:    Translation:Humans
    50. Shureiqi I, Chen D, Day RS, Zuo X, Hochman FL, Ross WA, Cole RA, Moy O, Morris JS, Xiao L, Newman RA, Yang P, Lippman SM. Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. Cancer Prev Res (Phila). 2010 Jul; 3(7):829-38. PMID: 20570882; PMCID: PMC2900425.
      Citations: 32     Fields:    Translation:Humans
    51. Zuo X, Peng Z, Moussalli MJ, Morris JS, Broaddus RR, Fischer SM, Shureiqi I. Targeted genetic disruption of peroxisome proliferator-activated receptor-delta and colonic tumorigenesis. J Natl Cancer Inst. 2009 May 20; 101(10):762-7. PMID: 19436036; PMCID: PMC2684551.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    52. Zuo X, Morris JS, Broaddus R, Shureiqi I. 15-LOX-1 transcription suppression through the NuRD complex in colon cancer cells. Oncogene. 2009 Mar 26; 28(12):1496-505. PMID: 19198625; PMCID: PMC2743348.
      Citations: 13     Fields:    Translation:HumansCells
    53. Zuo X, Morris JS, Shureiqi I. Chromatin modification requirements for 15-lipoxygenase-1 transcriptional reactivation in colon cancer cells. J Biol Chem. 2008 Nov 14; 283(46):31341-7. PMID: 18799463; PMCID: PMC2581547.
      Citations: 12     Fields:    Translation:HumansCells
    54. Kopetz S, Overman M, Chang DZ, Glover KY, Shureiqi I, Wolff RA, Abbruzzese JL, Eng C. Systematic survey of therapeutic trials for metastatic colorectal cancer: room for improvement in the critical pathway. J Clin Oncol. 2008 Apr 20; 26(12):2000-5. PMID: 18421052.
      Citations: 2     Fields:    Translation:Humans
    55. Wu Y, Fang B, Yang XQ, Wang L, Chen D, Krasnykh V, Carter BZ, Morris JS, Shureiqi I. Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer. Mol Ther. 2008 May; 16(5):886-92. PMID: 18388920; PMCID: PMC2377397.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    56. Zuo X, Shen L, Issa JP, Moy O, Morris JS, Lippman SM, Shureiqi I. 15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation. FASEB J. 2008 Jun; 22(6):1981-92. PMID: 18198215; PMCID: PMC2410033.
      Citations: 13     Fields:    Translation:HumansCells
    57. Shureiqi I, Zuo X, Broaddus R, Wu Y, Guan B, Morris JS, Lippman SM. The transcription factor GATA-6 is overexpressed in vivo and contributes to silencing 15-LOX-1 in vitro in human colon cancer. FASEB J. 2007 Mar; 21(3):743-53. PMID: 17167069; PMCID: PMC1847772.
      Citations: 31     Fields:    Translation:HumansCells
    58. Yang P, Chan D, Felix E, Madden T, Klein RD, Shureiqi I, Chen X, Dannenberg AJ, Newman RA. Determination of endogenous tissue inflammation profiles by LC/MS/MS: COX- and LOX-derived bioactive lipids. Prostaglandins Leukot Essent Fatty Acids. 2006 Dec; 75(6):385-95. PMID: 17011176.
      Citations: 36     Fields:    Translation:HumansAnimals
    59. Zuo X, Wu Y, Morris JS, Stimmel JB, Leesnitzer LM, Fischer SM, Lippman SM, Shureiqi I. Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity. Oncogene. 2006 Feb 23; 25(8):1225-41. PMID: 16288226; PMCID: PMC1432095.
      Citations: 51     Fields:    Translation:HumansCells
    60. Shureiqi I, Wu Y, Chen D, Yang XL, Guan B, Morris JS, Yang P, Newman RA, Broaddus R, Hamilton SR, Lynch P, Levin B, Fischer SM, Lippman SM. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. Cancer Res. 2005 Dec 15; 65(24):11486-92. PMID: 16357157; PMCID: PMC1564070.
      Citations: 39     Fields:    Translation:HumansCells
    61. Deguchi A, Xing SW, Shureiqi I, Yang P, Newman RA, Lippman SM, Feinmark SJ, Oehlen B, Weinstein IB. Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells. Cancer Res. 2005 Sep 15; 65(18):8442-7. PMID: 16166323.
      Citations: 17     Fields:    Translation:HumansCells
    62. Hsi LC, Xi X, Lotan R, Shureiqi I, Lippman SM. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. Cancer Res. 2004 Dec 01; 64(23):8778-81. PMID: 15574791.
      Citations: 25     Fields:    Translation:HumansCells
    63. Duffield-Lillico AJ, Shureiqi I, Lippman SM. Can selenium prevent colorectal cancer? A signpost from epidemiology. J Natl Cancer Inst. 2004 Nov 17; 96(22):1645-7. PMID: 15547171.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    64. Shureiqi I, Jiang W, Zuo X, Wu Y, Stimmel JB, Leesnitzer LM, Morris JS, Fan HZ, Fischer SM, Lippman SM. The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9968-73. PMID: 12909723; PMCID: PMC187904.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    65. Shureiqi I, Jiang W, Fischer SM, Xu X, Chen D, Lee JJ, Lotan R, Lippman SM. GATA-6 transcriptional regulation of 15-lipoxygenase-1 during NSAID-induced apoptosis in colorectal cancer cells. Cancer Res. 2002 Feb 15; 62(4):1178-83. PMID: 11861401.
      Citations: 15     Fields:    Translation:HumansCells
    66. Shureiqi I, Cantor SB, Lippman SM, Brenner DE, Chernew ME, Fendrick AM. Clinical and economic impact of multiple gated acquisition scan monitoring during anthracycline therapy. Br J Cancer. 2002 Jan 21; 86(2):226-32. PMID: 11870511; PMCID: PMC2375190.
      Citations: 4     Fields:    Translation:Humans
    67. McGinn CJ, Zalupski MM, Shureiqi I, Robertson JM, Eckhauser FE, Smith DC, Brown D, Hejna G, Strawderman M, Normolle D, Lawrence TS. Phase I trial of radiation dose escalation with concurrent weekly full-dose gemcitabine in patients with advanced pancreatic cancer. J Clin Oncol. 2001 Nov 15; 19(22):4202-8. PMID: 11709563.
      Citations: 69     Fields:    Translation:HumansCTClinical Trials
    68. Shureiqi I, Cooksley CD, Morris J, Soliman AS, Levin B, Lippman SM. Effect of age on risk of second primary colorectal cancer. J Natl Cancer Inst. 2001 Aug 15; 93(16):1264-6. PMID: 11504772.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    69. Shureiqi I, Xu X, Chen D, Lotan R, Morris JS, Fischer SM, Lippman SM. Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. Cancer Res. 2001 Jun 15; 61(12):4879-84. PMID: 11406566.
      Citations: 30     Fields:    Translation:HumansCells
    70. Krishnan K, Ruffin MT, Normolle D, Shureiqi I, Burney K, Bailey J, Peters-Golden M, Rock CL, Boland CR, Brenner DE. Colonic mucosal prostaglandin E2 and cyclooxygenase expression before and after low aspirin doses in subjects at high risk or at normal risk for colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2001 May; 10(5):447-53. PMID: 11352853.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    71. Shureiqi I, Chen D, Lotan R, Yang P, Newman RA, Fischer SM, Lippman SM. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer Res. 2000 Dec 15; 60(24):6846-50. PMID: 11156377.
      Citations: 41     Fields:    Translation:HumansCells
    72. Shureiqi I, Chen D, Lee JJ, Yang P, Newman RA, Brenner DE, Lotan R, Fischer SM, Lippman SM. 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst. 2000 Jul 19; 92(14):1136-42. PMID: 10904086.
      Citations: 50     Fields:    Translation:HumansCells
    73. Shureiqi I, Reddy P, Brenner DE. Chemoprevention: general perspective. Crit Rev Oncol Hematol. 2000 Mar; 33(3):157-67. PMID: 10789490.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    74. Shureiqi I, Wojno KJ, Poore JA, Reddy RG, Moussalli MJ, Spindler SA, Greenson JK, Normolle D, Hasan AA, Lawrence TS, Brenner DE. Decreased 13-S-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers. Carcinogenesis. 1999 Oct; 20(10):1985-95. PMID: 10506115.
      Citations: 63     Fields:    Translation:HumansCells
    75. Shureiqi I, Brenner DE. Chemoprevention of epithelial cancers. Curr Opin Oncol. 1999 Sep; 11(5):408-13. PMID: 10505781.
      Citations: 1     Fields:    Translation:HumansAnimals
    76. Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer. Investigational New Drugs.
    77. Omega-3-acid ethyl esters block the protumorigenic effects of obesity in mouse models of postmenopausal basal-like and claudin-low breast cancer. Cancer Prevention Research. 8:796-806.
    78. Phase IB study of vemurafenib in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with BRAFV600E mutation. Cancer Discovery. 6:1352-1365.
    79. ALOX15 as a suppressor of inflammation and cancer. Prostaglandins and Other Lipid Mediators.
    80. Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials. Annals of Oncology. 27:1068-1074.
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