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LEI LI

TitleProfessor
InstitutionMD Anderson
DepartmentExperimental Radiation Oncology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Li L. The multiple fronts of conquering cancer. Sci China Life Sci. 2017 10; 60(10):1055-1057. PMID: 29119375.
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    2. Li L. Overdose the addiction--A new strategy to ablate cancer cells. Sci China Life Sci. 2015 Nov; 58(11):1169-70. PMID: 26335741.
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    3. Tian Y, Paramasivam M, Ghosal G, Chen D, Shen X, Huang Y, Akhter S, Legerski R, Chen J, Seidman MM, Qin J, Li L. UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold. Cell Rep. 2015 Mar 31; 10(12):1957-66. PMID: 25818288.
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    4. Estrella JS, Li L, Rashid A, Wang H, Katz MH, Fleming JB, Abbruzzese JL, Wang H. Solid pseudopapillary neoplasm of the pancreas: clinicopathologic and survival analyses of 64 cases from a single institution. Am J Surg Pathol. 2014 Feb; 38(2):147-57. PMID: 24418850.
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    5. Smith S, Fox J, Mejia M, Ruangpradit W, Saberi A, Kim S, Choi Y, Oh S, Wang Y, Choi K, Li L, Hendrickson EA, Takeda S, Muller M, Myung K. Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity. PLoS One. 2014; 9(1):e87203. PMID: 24466340.
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    6. Wang H, Chen Y, Lin P, Li L, Zhou G, Liu G, Logsdon C, Jin J, Abbruzzese JL, Tan TH, Wang H. The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1. J Biol Chem. 2014 Feb 14; 289(7):4009-17. PMID: 24362026.
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    7. Shee C, Cox BD, Gu F, Luengas EM, Joshi MC, Chiu LY, Magnan D, Halliday JA, Frisch RL, Gibson JL, Nehring RB, Do HG, Hernandez M, Li L, Herman C, Hastings PJ, Bates D, Harris RS, Miller KM, Rosenberg SM. Engineered proteins detect spontaneous DNA breakage in human and bacterial cells. Elife. 2013 Oct 29; 2:e01222. PMID: 24171103.
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    8. Wang Y, Han X, Wu F, Leung JW, Lowery MG, Do H, Chen J, Shi C, Tian C, Li L, Gong W. Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res. 2013 Oct; 23(10):1215-28. PMID: 23999858.
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    9. Min JN, Tian Y, Xiao Y, Wu L, Li L, Chang S. The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability. Cell Res. 2013 Dec; 23(12):1396-413. PMID: 23979016.
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    10. Wang ML, Rule S, Martin P, Goy A, Auer R, Kahl BS, Jurczak W, Advani RH, Romaguera JE, Williams ME, Barrientos JC, Chmielowska E, Radford J, Stilgenbauer S, Dreyling M, Jedrzejczak WW, Johnson P, Spurgeon SE, Li L, Zhang L, Newberry K, Ou Z, Cheng N, Fang B, McGreivy J, Clow F, Buggy JJ, Chang BY, Beaupre DM, Kunkel LA, Blum KA. Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma. N Engl J Med. 2013 Aug 08; 369(6):507-16. PMID: 23782157.
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    11. Wang Y, Leung JW, Jiang Y, Lowery MG, Do H, Vasquez KM, Chen J, Wang W, Li L. FANCM and FAAP24 maintain genome stability via cooperative as well as unique functions. Mol Cell. 2013 Mar 07; 49(5):997-1009. PMID: 23333308.
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    12. Leung JW, Ghosal G, Wang W, Shen X, Wang J, Li L, Chen J. Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress. J Biol Chem. 2013 Mar 01; 288(9):6342-50. PMID: 23329831.
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    13. Li L, Othman M, Rashid A, Wang H, Li Z, Katz MH, Lee JE, Pisters PW, Abbruzzese JL, Fleming JB, Wang H. Solid pseudopapillary neoplasm of the pancreas with prominent atypical multinucleated giant tumour cells. Histopathology. 2013 Feb; 62(3):465-71. PMID: 23134473.
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    14. Yan Z, Guo R, Paramasivam M, Shen W, Ling C, Fox D, Wang Y, Oostra AB, Kuehl J, Lee DY, Takata M, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Li L, Seidman MM, Wang W. A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. Mol Cell. 2012 Jul 13; 47(1):61-75. PMID: 22705371.
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    15. Leung JW, Wang Y, Fong KW, Huen MS, Li L, Chen J. Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):4491-6. PMID: 22396592.
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    16. Zhou L, Ying W, Han Y, Chen M, Yan Y, Li L, Zhu Z, Zheng Z, Jia W, Yang R, Qian X. A proteome reference map and virulence factors analysis of Yersinia pestis 91001. J Proteomics. 2012 Jan 04; 75(3):894-907. PMID: 22040741.
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    17. Li L. BRCA1 forks over new roles in DNA-damage response- before and beyond the breaks. Mol Cell. 2011 Oct 21; 44(2):174-6. PMID: 22017867.
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    18. Mi W, Liu X, Jia W, Li L, Cai Y, Ying W, Qian X. Toward a high resolution 2-DE profile of the normal human liver proteome using ultra-zoom gels. Sci China Life Sci. 2011 Jan; 54(1):25-33. PMID: 21253867.
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    19. Wang Y, Li L. Detecting recruitment of DNA damage response factors through the eChIP approach. Methods Mol Biol. 2011; 782:245-55. PMID: 21870297.
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    20. Chen H, You MJ, Jiang Y, Wang W, Li L. RMI1 attenuates tumor development and is essential for early embryonic survival. Mol Carcinog. 2011 Feb; 50(2):80-8. PMID: 21229605.
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    21. Jiang Y, Wang X, Bao S, Guo R, Johnson DG, Shen X, Li L. INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway. Proc Natl Acad Sci U S A. 2010 Oct 05; 107(40):17274-9. PMID: 20855601.
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    22. Xu D, Muniandy P, Leo E, Yin J, Thangavel S, Shen X, Ii M, Agama K, Guo R, Fox D, Meetei AR, Wilson L, Nguyen H, Weng NP, Brill SJ, Li L, Vindigni A, Pommier Y, Seidman M, Wang W. Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication. EMBO J. 2010 Sep 15; 29(18):3140-55. PMID: 20711169.
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    23. Shen X, Li L. Mutagenic repair of DNA interstrand crosslinks. Environ Mol Mutagen. 2010 Jul; 51(6):493-9. PMID: 20209624.
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    24. Zhou Z, Sun X, Zou Z, Sun L, Zhang T, Guo S, Wen Y, Liu L, Wang Y, Qin J, Li L, Gong W, Bao S. PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130. Cell Res. 2010 Sep; 20(9):1023-33. PMID: 20421892.
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    25. Yan Z, Delannoy M, Ling C, Daee D, Osman F, Muniandy PA, Shen X, Oostra AB, Du H, Steltenpool J, Lin T, Schuster B, D├ęcaillet C, Stasiak A, Stasiak AZ, Stone S, Hoatlin ME, Schindler D, Woodcock CL, Joenje H, Sen R, de Winter JP, Li L, Seidman MM, Whitby MC, Myung K, Constantinou A, Wang W. A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell. 2010 Mar 26; 37(6):865-78. PMID: 20347428.
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    26. Liu X, Zhang J, Zheng Z, Yang X, Jia W, Li L, Gong Y, Cai Y, Zhu Y, He F, Ying W, Qian X. A systematic N-terminal peptide quantitative labeling strategy for differential proteomic analysis. Proteomics Clin Appl. 2010 Jul; 4(6-7):633-43. PMID: 21137082.
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    27. First insight into the human liver proteome from PROTEOME(SKY)-LIVER(Hu) 1.0, a publicly available database. J Proteome Res. 2010 Jan; 9(1):79-94. PMID: 19653699.
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    28. Ying W, Perlman DH, Li L, Th├ęberge R, Costello CE, McComb ME. Highly efficient and selective enrichment of peptide subsets combining fluorous chemistry with reversed-phase chromatography. Rapid Commun Mass Spectrom. 2009 Dec; 23(24):4019-30. PMID: 19924777.
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    29. Bu W, Xin L, Toneff M, Li L, Li Y. Lentivirus vectors for stably introducing genes into mammary epithelial cells in vivo. J Mammary Gland Biol Neoplasia. 2009 Dec; 14(4):401-4. PMID: 19936990.
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    30. Shen X, Do H, Li Y, Chung WH, Tomasz M, de Winter JP, Xia B, Elledge SJ, Wang W, Li L. Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Mol Cell. 2009 Sep 11; 35(5):716-23. PMID: 19748364.
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    31. Yuan C, Jiao L, Yang L, Ying W, Hu Z, Liu J, Cui F, Li L, Qian L, Teng Y, Hang H, Qian X, Yang X. The up-regulation of 14-3-3 proteins in Smad4 deficient epidermis and hair follicles at catagen. Proteomics. 2008 Jun; 8(11):2230-43. PMID: 18446800.
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    32. Bae JB, Mukhopadhyay SS, Liu L, Zhang N, Tan J, Akhter S, Liu X, Shen X, Li L, Legerski RJ. Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links. Oncogene. 2008 Aug 28; 27(37):5045-56. PMID: 18469862.
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    33. Zhang Q, Li L, Liu L, Li Y, Yuan L, Song L, Wu Z. Effects of the polysaccharide fraction of Urtica fissa on castrated rat prostate hyperplasia induced by testosterone propionate. Phytomedicine. 2008 Sep; 15(9):722-7. PMID: 18242969.
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    34. Zhang N, Liu X, Li L, Legerski R. Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst). 2007 Nov; 6(11):1670-8. PMID: 17669695.
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    35. Park JI, Ji H, Jun S, Gu D, Hikasa H, Li L, Sokol SY, McCrea PD. Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals. Dev Cell. 2006 Nov; 11(5):683-95. PMID: 17084360.
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    36. Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, Elledge SJ, Li L. Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell. 2006 Aug 04; 23(3):331-41. PMID: 16885023.
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    37. Shen X, Jun S, O'Neal LE, Sonoda E, Bemark M, Sale JE, Li L. REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA). J Biol Chem. 2006 May 19; 281(20):13869-72. PMID: 16571727.
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    38. Zheng H, Wang X, Legerski RJ, Glazer PM, Li L. Repair of DNA interstrand cross-links: interactions between homology-dependent and homology-independent pathways. DNA Repair (Amst). 2006 May 10; 5(5):566-74. PMID: 16569514.
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    39. Wu L, Bachrati CZ, Ou J, Xu C, Yin J, Chang M, Wang W, Li L, Brown GW, Hickson ID. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc Natl Acad Sci U S A. 2006 Mar 14; 103(11):4068-73. PMID: 16537486.
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    40. Zhang N, Kaur R, Lu X, Shen X, Li L, Legerski RJ. The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J Biol Chem. 2005 Dec 09; 280(49):40559-67. PMID: 16223718.
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    41. Yin J, Sobeck A, Xu C, Meetei AR, Hoatlin M, Li L, Wang W. BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity. EMBO J. 2005 Apr 06; 24(7):1465-76. PMID: 15775963.
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    42. Li L, Zou L. Sensing, signaling, and responding to DNA damage: organization of the checkpoint pathways in mammalian cells. J Cell Biochem. 2005 Feb 01; 94(2):298-306. PMID: 15578575.
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    43. Bao S, Lu T, Wang X, Zheng H, Wang LE, Wei Q, Hittelman WN, Li L. Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defects. Oncogene. 2004 Jul 22; 23(33):5586-93. PMID: 15184880.
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    44. Zhang Y, Wang J, Li L, Ying W, Cai Y, Qian X. [Studies on relationship between peak capacity and column length for separation of peptides by high performance liquid chromatography]. Se Pu. 2004 Jan; 22(1):24-6. PMID: 15712938.
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    45. Chen X, Li Y, Wei K, Li L, Liu W, Zhu Y, Qiu Z, He F. The potentiation role of hepatopoietin on activator protein-1 is dependent on its sulfhydryl oxidase activity. J Biol Chem. 2003 Dec 05; 278(49):49022-30. PMID: 14500725.
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    46. Wang W, Yang Y, Li L, Shi Y. Synleurin, a novel leucine-rich repeat protein that increases the intensity of pleiotropic cytokine responses. Biochem Biophys Res Commun. 2003 Jun 13; 305(4):981-8. PMID: 12767927.
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    47. Wang JL, Zhang YJ, Cai Y, Li L, Liu SY, Yang HY, Qian XH. [Analysis of protein phosphorylation by combination of IMAC, phosphatase with biological mass spectrometry]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 May; 35(5):459-66. PMID: 12766808.
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    48. Wang X, Zou L, Zheng H, Wei Q, Elledge SJ, Li L. Genomic instability and endoreduplication triggered by RAD17 deletion. Genes Dev. 2003 Apr 15; 17(8):965-70. PMID: 12672690.
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    49. Qin J, Li L. Molecular anatomy of the DNA damage and replication checkpoints. Radiat Res. 2003 Feb; 159(2):139-48. PMID: 12537518.
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    50. Zheng H, Wang X, Warren AJ, Legerski RJ, Nairn RS, Hamilton JW, Li L. Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Mol Cell Biol. 2003 Jan; 23(2):754-61. PMID: 12509472.
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    51. Sturgis EM, Castillo EJ, Li L, Eicher SA, Strom SS, Spitz MR, Wei Q. XPD/ERCC2 EXON 8 Polymorphisms: rarity and lack of significance in risk of squamous cell carcinoma of the head and neck. Oral Oncol. 2002 Jul; 38(5):475-7. PMID: 12110342.
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    52. Vasquez KM, Christensen J, Li L, Finch RA, Glazer PM. Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proc Natl Acad Sci U S A. 2002 Apr 30; 99(9):5848-53. PMID: 11972036.
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    53. Zheng Y, Li L, Shen H, Sturgis EM, Eicher SA, Strom SS, Spitz MR, Wei Q. Polymorphic hCHK2/hCds1 codon 84 allele and risk of squamous cell carcinoma of the head and neck--a case-control analysis. Carcinogenesis. 2001 Dec; 22(12):2005-8. PMID: 11751432.
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    54. Wang X, Wang L, Callister MD, Putnam JB, Mao L, Li L. Human Rad17 is phosphorylated upon DNA damage and also overexpressed in primary non-small cell lung cancer tissues. Cancer Res. 2001 Oct 15; 61(20):7417-21. PMID: 11606373.
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    55. Li L, Story M, Legerski RJ. Cellular responses to ionizing radiation damage. Int J Radiat Oncol Biol Phys. 2001 Mar 15; 49(4):1157-62. PMID: 11240259.
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    56. Wang X, Peterson CA, Zheng H, Nairn RS, Legerski RJ, Li L. Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair. Mol Cell Biol. 2001 Feb; 21(3):713-20. PMID: 11154259.
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    57. Zhang N, Zhang X, Peterson C, Li L, Legerski R. Differential processing of UV mimetic and interstrand crosslink damage by XPF cell extracts. Nucleic Acids Res. 2000 Dec 01; 28(23):4800-4. PMID: 11095693.
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    58. Sturgis EM, Zheng R, Li L, Castillo EJ, Eicher SA, Chen M, Strom SS, Spitz MR, Wei Q. XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis. Carcinogenesis. 2000 Dec; 21(12):2219-23. PMID: 11133811.
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    59. Li L, Peterson CA, Zhang X, Legerski RJ. Requirement for PCNA and RPA in interstrand crosslink-induced DNA synthesis. Nucleic Acids Res. 2000 Mar 15; 28(6):1424-7. PMID: 10684938.
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    60. Sturgis EM, Castillo EJ, Li L, Zheng R, Eicher SA, Clayman GL, Strom SS, Spitz MR, Wei Q. Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck. Carcinogenesis. 1999 Nov; 20(11):2125-9. PMID: 10545415.
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    61. Li L, Liao WS. An upstream repressor element that contributes to hepatocyte-specific expression of the rat serum amyloid A1 gene. Biochem Biophys Res Commun. 1999 Oct 22; 264(2):395-403. PMID: 10529375.
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    62. Cheng L, Guan Y, Li L, Legerski RJ, Einspahr J, Bangert J, Alberts DS, Wei Q. Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction. Cancer Epidemiol Biomarkers Prev. 1999 Sep; 8(9):801-7. PMID: 10498399.
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    63. Li L, Peterson CA, Lu X, Wei P, Legerski RJ. Interstrand cross-links induce DNA synthesis in damaged and undamaged plasmids in mammalian cell extracts. Mol Cell Biol. 1999 Aug; 19(8):5619-30. PMID: 10409751.
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    64. Li L, Peterson CA, Kanter-Smoler G, Wei YF, Ramagli LS, Sunnerhagen P, Siciliano MJ, Legerski RJ. hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene. 1999 Mar 04; 18(9):1689-99. PMID: 10208430.
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    65. Marathi UK, Dahlen M, Sunnerhagen P, Romero AV, Ramagli LS, Siciliano MJ, Li L, Legerski RJ. RAD1, a human structural homolog of the Schizosaccharomyces pombe RAD1 cell cycle checkpoint gene. Genomics. 1998 Dec 01; 54(2):344-7. PMID: 9828139.
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    66. Khan SG, Levy HL, Legerski R, Quackenbush E, Reardon JT, Emmert S, Sancar A, Li L, Schneider TD, Cleaver JE, Kraemer KH. Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia. J Invest Dermatol. 1998 Nov; 111(5):791-6. PMID: 9804340.
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    67. Li L, Lu X, Peterson C, Legerski R. XPC interacts with both HHR23B and HHR23A in vivo. Mutat Res. 1997 May 01; 383(3):197-203. PMID: 9164480.
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    68. Wei Q, Guan Y, Cheng L, Radinsky R, Bar-Eli M, Tsan R, Li L, Legerski RJ. Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction. Pathobiology. 1997; 65(6):293-300. PMID: 9491849.
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    69. Li L, Peterson C, Legerski R. Sequence of the mouse XPC cDNA and genomic structure of the human XPC gene. Nucleic Acids Res. 1996 Mar 15; 24(6):1026-8. PMID: 8604333.
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    70. Li L, Lu X, Peterson CA, Legerski RJ. An interaction between the DNA repair factor XPA and replication protein A appears essential for nucleotide excision repair. Mol Cell Biol. 1995 Oct; 15(10):5396-402. PMID: 7565690.
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    71. Pan ZQ, Reardon JT, Li L, Flores-Rozas H, Legerski R, Sancar A, Hurwitz J. Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21. J Biol Chem. 1995 Sep 15; 270(37):22008-16. PMID: 7665622.
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    72. Henning KA, Li L, Iyer N, McDaniel LD, Reagan MS, Legerski R, Schultz RA, Stefanini M, Lehmann AR, Mayne LV, Friedberg EC. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell. 1995 Aug 25; 82(4):555-64. PMID: 7664335.
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    73. Liao WS, Lu SY, Huang J, Li L, Bing Z. Transcription factors as targets of cytokine signals. Ann N Y Acad Sci. 1995 Jul 21; 762:238-50; discussion 251. PMID: 7668530.
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    74. Li L, Peterson CA, Lu X, Legerski RJ. Mutations in XPA that prevent association with ERCC1 are defective in nucleotide excision repair. Mol Cell Biol. 1995 Apr; 15(4):1993-8. PMID: 7891694.
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    75. Li L, Elledge SJ, Peterson CA, Bales ES, Legerski RJ. Specific association between the human DNA repair proteins XPA and ERCC1. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):5012-6. PMID: 8197174.
      View in: PubMed
    76. Legerski RJ, Liu P, Li L, Peterson CA, Zhao Y, Leach RJ, Naylor SL, Siciliano MJ. Assignment of xeroderma pigmentosum group C (XPC) gene to chromosome 3p25. Genomics. 1994 May 01; 21(1):266-9. PMID: 8088800.
      View in: PubMed
    77. Li L, Bales ES, Peterson CA, Legerski RJ. Characterization of molecular defects in xeroderma pigmentosum group C. Nat Genet. 1993 Dec; 5(4):413-7. PMID: 8298653.
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    78. Accumulation and phosphorylation of RecQ-mediated genome instability protein 1 (RMI1) at serine 284 and serine 292 during mitosis. International Journal of Molecular Sciences. 16:26395-26405.
    79. The 2015 Albert Lasker Basic Medical Research Award. Science China Life Sciences. 59:103-105.
    80. Erratum to. Science China Life Sciences. 59:330.
    81. Erratum. Carcinogenesis. 22:363.
    82. Nucleotide excision repair. 65-85.
    83. Modularized Functions of the Fanconi Anemia Core Complex [Cell Reports 7, (2014), 1849-1857]. Cell Reports. 14:2761-2763.
    84. DNA repair, genetic instability, and cancer.
    85. DNA repair capability and cancer risk. Cancer Bulletin. 46:228-232.
    86. Nature Communications. 6.
    87. Preface. Unknown Journal. vii-ix.
    88. LIG4 mediates Wnt signalling-induced radioresistance. Nature Communications. 7.
    89. DNA crosslinking damage and cancer - a tale of friend and foe. Translational Cancer Research. 2:144-154.
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