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PATRICK M LYNCH

TitleProfessor
InstitutionMD Anderson
DepartmentGastroenterology Hepatology & Nutrition
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Meuser E, Chang K, Walters A, Hurley JJ, West HD, Perry I, Mort M, Reyes-Uribe L, Truscott R, Jones N, Lawrence R, Jenkins G, Giles P, Dolwani S, Al-Sarireh B, Hawkes N, Short E, Williams GT, Taggart MW, Luetchford K, Lynch PM, Terlouw D, Nielsen M, Walton SJ, Latchford A, Clark SK, Sampson JR, Vilar E, Thomas LE, Meuser E, Chang K, Walters A, Hurley JJ, West HD, Perry I, Mort M, Reyes-Uribe L, Truscott R, Jones N, Lawrence R, Jenkins G, Giles P, Dolwani S, Al-Sarireh B, Hawkes N, Short E, Williams GT, Taggart MW, Luetchford K, Lynch PM, Terlouw D, Nielsen M, Walton SJ, Latchford A, Clark SK, Sampson JR, Vilar E, Thomas LE. PIGA Mutations and Glycosylphosphatidylinositol Anchor Dysregulation in Polyposis-Associated Duodenal Tumorigenesis. Mol Cancer Res. 2024 06 04; 22(6):515-523. PMID: 38546397; PMCID: PMC11148540.
      Citations:    Fields:    Translation:Humans
    2. Rodriguez-Pascual J, Bolivar AM, Duzagac F, Deng N, Reyes-Uribe L, Chang K, Wu W, Bowen CM, Taggart MW, Thirumurthi S, Lynch PM, You YN, Lipkin SM, Kopetz S, Scheet P, Lizee GA, Reuben A, Sinha KM, Vilar E. Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention. Gastroenterology. 2024 05; 166(5):787-801.e11. PMID: 38244726; PMCID: PMC11034773.
      Citations: 3     Fields:    Translation:HumansCells
    3. Deng N, Reyes-Uribe L, Fahrmann JF, Thoman WS, Munsell MF, Dennison JB, Murage E, Wu R, Hawk ET, Thirumurthi S, Lynch PM, Dieli-Conwright CM, Lazar AJ, Jindal S, Chu K, Chelvanambi M, Basen-Engquist K, Li Y, Wargo JA, McAllister F, Allison JP, Sharma P, Sinha KM, Hanash S, Gilchrist SC, Vilar E. Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-Associated Immunity in Lynch Syndrome. Clin Cancer Res. 2023 11 01; 29(21):4361-4372. PMID: 37724990; PMCID: PMC10618653.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    4. Del Carmen G, Reyes-Uribe L, Goyco D, Evans K, Bowen CM, Kinnison JL, Sepeda VO, Weber DM, Moskowitz J, Mork ME, Thirumurthi S, Lynch PM, Rodriguez-Bigas MA, Taggart MW, You YN, Vilar E. Colorectal surveillance outcomes from an institutional longitudinal cohort of lynch syndrome carriers. Front Oncol. 2023; 13:1146825. PMID: 37168379; PMCID: PMC10164917.
      Citations:    
    5. Nehme F, Armstrong AE, Taherian M, Lynch PM, Richards DM, Casanova DN, Ge PS. Endoscopic submucosal dissection using an integrated needle-type knife and insulated-tip knife in a single device. VideoGIE. 2023 Mar; 8(3):96-99. PMID: 36935802; PMCID: PMC10020168.
      Citations:    
    6. Farha N, Kumar S, Katona BW, H?neburg R, Lynch PM, Gupta S, Burke CA. The Approach to Performance of Quality Upper Endoscopy in Lynch Syndrome (QUELS): An International Expert Statement. J Clin Gastroenterol. 2023 Jan 01; 57(1):31-38. PMID: 36504228.
      Citations:    Fields:    Translation:Humans
    7. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Sepp?l? TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A, Guillem JG, Houwen BBSL, Kahi C, Kalady MF, Kastrinos F, K?hn F, Laghi L, Latchford A, Liska D, Lynch P, Malesci A, Mauri G, Meldolesi E, M?ller P, Monahan KJ, M?slein G, Murphy CC, Nass K, Ng K, Oliani C, Papaleo E, Patel SG, Puzzono M, Remo A, Ricciardiello L, Ripamonti CI, Siena S, Singh SK, Stadler ZK, Stanich PP, Syngal S, Turi S, Urso ED, Valle L, Vanni VS, Vilar E, Vitellaro M, You YN, Yurgelun MB, Zuppardo RA, Stoffel EM, Associazione Italiana Familiarit? Ereditariet? Tumori, Collaborative Group of the Americas on Inherited Gastrointestinal Cancer, European Hereditary Tumour Group, and the International Society for Gastrointestinal Hereditary Tumo. Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines. Clin Gastroenterol Hepatol. 2023 03; 21(3):581-603.e33. PMID: 36549470; PMCID: PMC11207185.
      Citations: 6     Fields:    Translation:Humans
    8. Shyr C, Blackford AL, Huang T, Ke J, Ouardaoui N, Trippa L, Syngal S, Ukaegbu C, Uno H, Nafa K, Stadler ZK, Offit K, Amos CI, Lynch PM, Chen S, Giardiello FM, Buchanan DD, Hopper JL, Jenkins MA, Southey MC, Win AK, Figueiredo JC, Braun D, Parmigiani G. A validation of models for prediction of pathogenic variants in mismatch repair genes. Genet Med. 2022 10; 24(10):2155-2166. PMID: 35997715; PMCID: PMC10312204.
      Citations:    
    9. Lee JH, Yu AC, Ali FS, Ahmed O, Lynch P, Ge P, Coronel E, Kim M, Coronel M, Folloder J, Katz MHG. The conundrum in endoscopic management of duodenal polyps: a tertiary cancer center experience. Expert Rev Gastroenterol Hepatol. 2022 Jun; 16(6):569-576. PMID: 35687675.
      Citations:    Fields:    Translation:Humans
    10. Kumar S, Bahdi F, Emelogu IK, Yu AC, Coronel M, Ge PS, Coronel E, Ajani JA, Weston B, Lynch P, Ross WA, Lee JH. How much progress have we made?: a 20-year experience regarding esophageal stents for the palliation of malignant dysphagia. Dis Esophagus. 2022 Jun 15; 35(6). PMID: 34937091.
      Citations:    Fields:    Translation:Humans
    11. Stoffel EM, Burke CA, Dekker E, Samadder NJ, Van Cutsem E, Lynch PM, Wise PE, Lim RM, Boytim ML, Du W, Bruckheimer EM, Cohen A, Church J, FAP-310 Investigators, Balaguer F, H?neburg R. Combination of Sulindac and Eflornithine Delays the Need for Lower Gastrointestinal Surgery in Patients With Familial Adenomatous Polyposis: Post Hoc Analysis of a Randomized Clinical Trial. Dis Colon Rectum. 2022 Apr 01; 65(4):536-545. PMID: 34261858.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    12. Basen-Engquist K, Raber M, Strong LL, Schembre S, Li L, Arun B, Lu K, You N, Vilar E, Lynch P, Fares S, Peterson SK. Optimization of an mHealth lifestyle intervention for families with hereditary cancer syndromes: Study protocol for a multiphase optimization strategy feasibility study. Contemp Clin Trials. 2022 02; 113:106662. PMID: 34971795.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    13. Weiss JM, Gupta S, Burke CA, Axell L, Chen LM, Chung DC, Clayback KM, Dallas S, Felder S, Gbolahan O, Giardiello FM, Grady W, Hall MJ, Hampel H, Hodan R, Idos G, Kanth P, Katona B, Lamps L, Llor X, Lynch PM, Markowitz AJ, Pirzadeh-Miller S, Samadder NJ, Shibata D, Swanson BJ, Szymaniak BM, Wiesner GL, Wolf A, Yurgelun MB, Zakhour M, Darlow SD, Dwyer MA, Campbell M. NCCN Guidelines? Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 1.2021. J Natl Compr Canc Netw. 2021 10 15; 19(10):1122-1132. PMID: 34666312.
      Citations: 16     Fields:    Translation:Humans
    14. Bowen CM, Walter L, Borras E, Wu W, Ozcan Z, Chang K, Bommi PV, Taggart MW, Thirumurthi S, Lynch PM, Reyes-Uribe L, Scheet PA, Sinha KM, Vilar E. Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis. Cancer Prev Res (Phila). 2021 09; 14(9):851-862. PMID: 34266857; PMCID: PMC8416926.
      Citations:    Fields:    Translation:HumansAnimalsCells
    15. Pande M, Peterson S, Lynch PM. Development and evaluation of an online, patient-driven, family outreach intervention to facilitate sharing of genetic risk information in families with Lynch syndrome. J Med Genet. 2022 06; 59(6):589-596. PMID: 34006620.
      Citations: 1     Fields:    Translation:Humans
    16. Lynch PM. Low-dose aspirin and mesalazine for patients with familial adenomatous polyposis. Lancet Gastroenterol Hepatol. 2021 06; 6(6):418-419. PMID: 33812493.
      Citations: 1     Fields:    Translation:Humans
    17. Bommi PV, Bowen CM, Reyes-Uribe L, Wu W, Katayama H, Rocha P, Parra ER, Francisco-Cruz A, Ozcan Z, Tosti E, Willis JA, Wu H, Taggart MW, Burks JK, Lynch PM, Edelmann W, Scheet PA, Wistuba II, Sinha KM, Hanash SM, Vilar E. The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells. Cancer Res. 2021 05 15; 81(10):2760-2773. PMID: 34003775; PMCID: PMC8318201.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    18. Lynch PM. The CAPP II trial of aspirin in Lynch syndrome/HNPCC: is it time for everyone to be treated? Fam Cancer. 2021 01; 20(1):9-11. PMID: 33420651.
      Citations:    Fields:    Translation:Humans
    19. Collaborative Group on Duodenal Polyposis in MAP, Thomas LE, Hurley JJ, Sanchez AA, Backman AS, Bjork J, Capella G, Clark SK, Colas C, Dekker E, Dolwani S, Ghorbanoghli Z, Gonn M, Gonzalez Romero S, Hes FJ, Jundi H, Kelland S, Latchford AR, Brito HL, Lynch PM, Meuser E, Mork ME, Mort M, Garcia MN, Nielsen M, Ricci MT, Saurin JC, Tuin KV, Vasen H, Vilar E, Vinet O, Vitellaro M, Walton SJ, West HD, Sampson JR, Azn?rez MR, Parc Y. Duodenal Adenomas and Cancer in MUTYH-associated Polyposis: An International Cohort Study. Gastroenterology. 2021 02; 160(3):952-954.e4. PMID: 33130102.
      Citations: 5     Fields:    Translation:Humans
    20. Burke CA, Dekker E, Lynch P, Samadder NJ, Balaguer F, H?neburg R, Burn J, Castells A, Gallinger S, Lim R, Stoffel EM, Gupta S, Henderson A, Kallenberg FG, Kanth P, Roos VH, Ginsberg GG, Sinicrope FA, Strassburg CP, Van Cutsem E, Church J, Lalloo F, Willingham FF, Wise PE, Grady WM, Ford M, Weiss JM, Gryfe R, Rustgi AK, Syngal S, Cohen A. Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis. N Engl J Med. 2020 09 10; 383(11):1028-1039. PMID: 32905675.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    21. Weston BR, Patel JM, Pande M, Lum PJ, Ross WA, Raju GS, Lynch PM, Coronel E, Ge PS, Lee JH. Efficacy of uncovered colonic stents for extrinsic versus intrinsic malignant large bowel obstruction. Surg Endosc. 2021 08; 35(8):4511-4519. PMID: 32909212.
      Citations: 2     Fields:    Translation:Humans
    22. Reyes-Uribe L, Wu W, Gelincik O, Bommi PV, Francisco-Cruz A, Solis LM, Lynch PM, Lim R, Stoffel EM, Kanth P, Samadder NJ, Mork ME, Taggart MW, Milne GL, Marnett LJ, Vornik L, Liu DD, Revuelta M, Chang K, You YN, Kopelovich L, Wistuba II, Lee JJ, Sei S, Shoemaker RH, Szabo E, Richmond E, Umar A, Perloff M, Brown PH, Lipkin SM, Vilar E. Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa. Gut. 2021 03; 70(3):555-566. PMID: 32641470; PMCID: PMC7790993.
      Citations: 9     Fields:    Translation:HumansAnimalsCTClinical Trials
    23. Lynch PM, Pande M. Refining Risk Estimates in Hereditary Nonpolyposis Colorectal Cancer: Are We There Yet? JNCI Cancer Spectr. 2020 Oct; 4(5):pkaa030. PMID: 33134819; PMCID: PMC7583147.
      Citations:    Fields:    
    24. Angsuwatcharakon P, Ahmed O, Lynch PM, Lum P, Gonzalez GN, Weston B, Coronel E, Katz MHG, Folloder J, Lee JH. Management of ampullary adenomas in familial adenomatous polyposis syndrome: 16 years of experience from a tertiary cancer center. Gastrointest Endosc. 2020 08; 92(2):323-330. PMID: 32145286.
      Citations: 3     Fields:    Translation:Humans
    25. Raju GS, Lum P, Abu-Sbeih H, Ross WA, Thirumurthi S, Miller E, Lynch P, Lee J, Bhutani MS, Shafi M, Weston B, Rashid A, Wang Y, Chang GJ, Carlson R, Hagan K, Davila M, Stroehlein J. Cap-fitted endoscopic mucosal resection of =?20?mm colon flat lesions followed by argon plasma coagulation results in a low adenoma recurrence rate. Endosc Int Open. 2020 Feb; 8(2):E115-E121. PMID: 32010742; PMCID: PMC6976333.
      Citations: 2     
    26. Gupta S, Provenzale D, Llor X, Halverson AL, Grady W, Chung DC, Haraldsdottir S, Markowitz AJ, Slavin TP, Hampel H, CGC, Ness RM, Weiss JM, Ahnen DJ, Chen LM, Cooper G, Early DS, Giardiello FM, Hall MJ, Hamilton SR, Kanth P, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Mikkelson J, CGC, Peter S, Regenbogen SE, Dwyer MA, CGC, Ogba N. NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019. J Natl Compr Canc Netw. 2019 09 01; 17(9):1032-1041. PMID: 31487681.
      Citations: 68     Fields:    Translation:Humans
    27. Coletta AM, Peterson SK, Gatus LA, Krause KJ, Schembre SM, Gilchrist SC, Pande M, Vilar E, You YN, Rodriguez-Bigas MA, Strong LL, Lynch PM, Lu KH, Basen-Engquist K. Energy balance related lifestyle factors and risk of endometrial and colorectal cancer among individuals with lynch syndrome: a systematic review. Fam Cancer. 2019 10; 18(4):399-420. PMID: 31236808; PMCID: PMC6863045.
      Citations: 2     Fields:    Translation:Humans
    28. Delacruz RGC, Sandoval IT, Chang K, Miller BN, Reyes-Uribe L, Borras E, Lynch PM, Taggart MW, Hawk ET, Vilar E, Jones DA. Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas. Oncotarget. 2019 Jun 11; 10(39):3939-3951. PMID: 31231471; PMCID: PMC6570471.
      Citations: 2     Fields:    
    29. Mork ME, Rodriguez A, Bannon SA, Lynch PM, Rodriguez-Bigas MA, Thirumurthi S, You YN, Vilar E. Outcomes of disease-specific next-generation sequencing gene panel testing in adolescents and young adults with colorectal cancer. Cancer Genet. 2019 06; 235-236:77-83. PMID: 31101557.
      Citations:    Fields:    Translation:Humans
    30. Donato KM, Moore K, Parker WM, Peterson SK, Gritz ER, Amos CI, Lu KH, Lynch PM, Rodriguez-Bigas MA, You YN, Burton-Chase AM. Health and lifestyle behaviors in colorectal cancer survivors with and without Lynch syndrome. J Community Genet. 2020 Jan; 11(1):59-63. PMID: 31016603; PMCID: PMC6962402.
      Citations:    
    31. Mork M, Quesada PR, Bannon S, Montiel MF, Fleming JB, Lynch PM, Bhutani MS, Lee JH, McAllister F. Pancreatic Cancer Early Detection and Interception in an Atypical Case of Peutz-Jeghers Syndrome. Pancreas. 2019 04; 48(4):e29-e30. PMID: 30973470; PMCID: PMC6461374.
      Citations: 1     Fields:    Translation:Humans
    32. Raju G, Lum P, Ross W, Thirumurthi S, Miller E, Lynch P, Lee J, Bhutani MS, Shafi MA, Weston B, Blechacz B, Chang GJ, Hagan K, Rashid A, Davila M, Stroehlein J. Quality of endoscopy reporting at index colonoscopy significantly impacts outcome of subsequent EMR in patients with > 20?mm colon polyps. Endosc Int Open. 2019 Mar; 7(3):E361-E366. PMID: 30834295; PMCID: PMC6395098.
      Citations: 2     
    33. Lee JH, Emelogu I, Kukreja K, Ali FS, Nogueras-Gonzalez G, Lum P, Coronel E, Ross W, Raju GS, Lynch P, Thirumurthi S, Stroehlein J, Wang Y, You YN, Weston B. Safety and efficacy of metal stents for malignant colonic obstruction in patients treated with bevacizumab. Gastrointest Endosc. 2019 07; 90(1):116-124. PMID: 30797835.
      Citations: 3     Fields:    Translation:Humans
    34. Luo W, Fedda F, Lynch P, Tan D. CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And Treatment. Front Pharmacol. 2018; 9:1421. PMID: 30568591; PMCID: PMC6290068.
      Citations: 28     
    35. Chang K, Willis JA, Reumers J, Taggart MW, San Lucas FA, Thirumurthi S, Kanth P, Delker DA, Hagedorn CH, Lynch PM, Ellis LM, Hawk ET, Scheet PA, Kopetz S, Arts J, Guinney J, Dienstmann R, Vilar E. Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2. Ann Oncol. 2018 10 01; 29(10):2061-2067. PMID: 30412224; PMCID: PMC6225810.
      Citations: 18     Fields:    Translation:HumansCells
    36. Dashti SG, Win AK, Hardikar SS, Glombicki SE, Mallenahalli S, Thirumurthi S, Peterson SK, You YN, Buchanan DD, Figueiredo JC, Campbell PT, Gallinger S, Newcomb PA, Potter JD, Lindor NM, Le Marchand L, Haile RW, Hopper JL, Jenkins MA, Basen-Engquist KM, Lynch PM, Pande M. Physical activity and the risk of colorectal cancer in Lynch syndrome. Int J Cancer. 2018 11 01; 143(9):2250-2260. PMID: 29904935; PMCID: PMC6195467.
      Citations: 5     Fields:    Translation:Humans
    37. Chang K, Taggart MW, Reyes-Uribe L, Borras E, Riquelme E, Barnett RM, Leoni G, San Lucas FA, Catanese MT, Mori F, Diodoro MG, You YN, Hawk ET, Roszik J, Scheet P, Kopetz S, Nicosia A, Scarselli E, Lynch PM, McAllister F, Vilar E. Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome. JAMA Oncol. 2018 08 01; 4(8):1085-1092. PMID: 29710228; PMCID: PMC6087485.
      Citations: 31     Fields:    Translation:Humans
    38. Provenzale D, Gupta S, Ahnen DJ, Markowitz AJ, Chung DC, Mayer RJ, Regenbogen SE, Blanco AM, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Hall MJ, Halverson AL, Hamilton SR, Hampel H, Klapman JB, Larson DW, Lazenby AJ, Llor X, Lynch PM, Mikkelson J, Ness RM, Slavin TP, Sugandha S, Weiss JM, Dwyer MA, Ogba N. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 1.2018. J Natl Compr Canc Netw. 2018 08; 16(8):939-949. PMID: 30099370.
      Citations: 53     Fields:    Translation:HumansPHPublic Health
    39. Burton-Chase AM, Parker WM, Donato KM, McCormick S, Gritz ER, Amos CI, Lu KH, Lynch PM, Rodriguez-Bigas MA, Nancy You Y, Peterson SK. Health-related quality of life in colorectal cancer survivors: are there differences between sporadic and hereditary patients? J Patient Rep Outcomes. 2017; 2(1):21. PMID: 29757305; PMCID: PMC5934923.
      Citations: 1     
    40. Pande M, Joon A, Brewster AM, Chen WV, Hopper JL, Eng C, Shete S, Casey G, Schumacher F, Lin Y, Harrison TA, White E, Ahsan H, Andrulis IL, Whittemore AS, John EM, Ko Win A, Makalic E, Schmidt DF, Kapuscinski MK, Ochs-Balcom HM, Gallinger S, Jenkins MA, Newcomb PA, Lindor NM, Peters U, Amos CI, Lynch PM. Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies. PLoS One. 2018; 13(4):e0196245. PMID: 29698419; PMCID: PMC5919670.
      Citations: 1     Fields:    Translation:Humans
    41. Gupta S, Provenzale D, Regenbogen SE, Hampel H, Slavin TP, Hall MJ, Llor X, Chung DC, Ahnen DJ, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Markowitz AJ, Mayer RJ, Ness RM, Samadder NJ, Shike M, Sugandha S, Weiss JM, Dwyer MA, Ogba N. NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 3.2017. J Natl Compr Canc Netw. 2017 12; 15(12):1465-1475. PMID: 29223984.
      Citations: 46     Fields:    Translation:Humans
    42. Lynch PM. Colorectal Cancer Genetics Screening in the Community: Are We Ready? Can We Do It? Clin Gastroenterol Hepatol. 2018 01; 16(1):21-23. PMID: 28987506.
      Citations:    Fields:    Translation:HumansPHPublic Health
    43. Borras E, Chang K, Pande M, Cuddy A, Bosch JL, Bannon SA, Mork ME, Rodriguez-Bigas MA, Taggart MW, Lynch PM, You YN, Vilar E. In Silico Systems Biology Analysis of Variants of Uncertain Significance in Lynch Syndrome Supports the Prioritization of Functional Molecular Validation. Cancer Prev Res (Phila). 2017 Oct; 10(10):580-587. PMID: 28765196; PMCID: PMC5626617.
      Citations: 5     Fields:    Translation:HumansCells
    44. Burke CA, Phillips R, Berger MF, Li C, Essex MN, Iorga D, Lynch PM. Children's International Polyposis (CHIP) study: a randomized, double-blind, placebo-controlled study of celecoxib in children with familial adenomatous polyposis. Clin Exp Gastroenterol. 2017; 10:177-185. PMID: 28765715; PMCID: PMC5525455.
      Citations: 4     
    45. Mork ME, Rodriguez A, Taggart MW, Rodriguez-Bigas MA, Lynch PM, Bannon SA, You YN, Vilar E. Identification of MSH2 inversion of exons 1-7 in clinical evaluation of families with suspected Lynch syndrome. Fam Cancer. 2017 07; 16(3):357-361. PMID: 28004223; PMCID: PMC5479758.
      Citations: 4     Fields:    Translation:Humans
    46. Gausachs M, Borras E, Chang K, Gonzalez S, Azuara D, Delgado Amador A, Lopez-Doriga A, San Lucas FA, Sanjuan X, Paules MJ, Taggart MW, Davies GE, Ehli EA, Fowler J, Moreno V, Pineda M, You YN, Lynch PM, Lazaro C, Navin NE, Scheet PA, Hawk ET, Capella G, Vilar E. Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis. Clin Cancer Res. 2017 Oct 01; 23(19):5936-5947. PMID: 28645942; PMCID: PMC5626604.
      Citations: 14     Fields:    Translation:Humans
    47. Goldstein JB, Wu W, Borras E, Masand G, Cuddy A, Mork ME, Bannon SA, Lynch PM, Rodriguez-Bigas M, Taggart MW, Wu J, Scheet P, Kopetz S, You YN, Vilar E. Can Microsatellite Status of Colorectal Cancer Be Reliably Assessed after Neoadjuvant Therapy? Clin Cancer Res. 2017 Sep 01; 23(17):5246-5254. PMID: 28522602; PMCID: PMC6035875.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    48. Katz LH, Advani S, Burton-Chase AM, Fellman B, Polivka KM, Yuan Y, Lynch PM, Peterson SK. Cancer screening behaviors and risk perceptions among family members of colorectal cancer patients with unexplained mismatch repair deficiency. Fam Cancer. 2017 04; 16(2):231-237. PMID: 27832499; PMCID: PMC5945287.
      Citations: 3     Fields:    Translation:HumansCells
    49. Burton-Chase AM, Parker WM, Polivka KM, Gritz ER, Amos CI, Lu KH, Lynch PM, Rodriguez-Bigas MA, Nancy You Y, Peterson SK. A comparison between Lynch syndrome and sporadic colorectal cancer survivors' satisfaction with their healthcare providers. Cancer Med. 2017 03; 6(3):698-707. PMID: 28211618; PMCID: PMC5345658.
      Citations: 3     Fields:    Translation:Humans
    50. Sunga AY, Espenschied CR, Castillo D, Melas M, Herzog J, Bannon S, Cruz-Correa M, Lynch P, Solomon I, Gruber SB, Weitzel JN, Ricker C. Spectrum of mismatch repair gene mutations and clinical presentation of Hispanic individuals with Lynch syndrome. Cancer Genet. 2017 04; 212-213:1-7. PMID: 28449805; PMCID: PMC8800930.
      Citations: 3     Fields:    Translation:HumansCells
    51. Mork ME, Borras E, Taggart MW, Cuddy A, Bannon SA, You YN, Lynch PM, Ramirez PT, Rodriguez-Bigas MA, Vilar E. Identification of a novel PMS2 alteration c.505C>G (R169G) in trans with a PMS2 pathogenic mutation in a patient with constitutional mismatch repair deficiency. Fam Cancer. 2016 10; 15(4):587-91. PMID: 27017610; PMCID: PMC5011443.
      Citations: 1     Fields:    Translation:Humans
    52. Cassani LS, Lanke G, Chen HC, Wang X, Lynch P, Lee JH. Comparison of nonampullary duodenal adenomas in patients with familial adenomatous polyposis versus patients with sporadic adenomas. Gastrointest Endosc. 2017 Apr; 85(4):803-812. PMID: 27530072.
      Citations: 1     Fields:    Translation:Humans
    53. Provenzale D, Gupta S, Ahnen DJ, Bray T, Cannon JA, Cooper G, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Regenbogen SE, Samadder NJ, Shike M, Steinbach G, Weinberg D, Dwyer M, Darlow S. Genetic/Familial High-Risk Assessment: Colorectal Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 08; 14(8):1010-30. PMID: 27496117.
      Citations: 75     Fields:    Translation:HumansPHPublic Health
    54. de Rosa N, Rodriguez-Bigas MA, Chang GJ, Veerapong J, Borras E, Krishnan S, Bednarski B, Messick CA, Skibber JM, Feig BW, Lynch PM, Vilar E, You YN. DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics. J Clin Oncol. 2016 09 01; 34(25):3039-46. PMID: 27432916; PMCID: PMC5012714.
      Citations: 29     Fields:    Translation:HumansCells
    55. Lynch PM. Chemoprevention of familial adenomatous polyposis. Fam Cancer. 2016 07; 15(3):467-75. PMID: 27083160.
      Citations: 10     Fields:    Translation:Humans
    56. Borras E, San Lucas FA, Chang K, Zhou R, Masand G, Fowler J, Mork ME, You YN, Taggart MW, McAllister F, Jones DA, Davies GE, Edelmann W, Ehli EA, Lynch PM, Hawk ET, Capella G, Scheet P, Vilar E. Genomic Landscape of Colorectal Mucosa and Adenomas. Cancer Prev Res (Phila). 2016 06; 9(6):417-27. PMID: 27221540; PMCID: PMC4941624.
      Citations: 42     Fields:    Translation:HumansCells
    57. Ricciardiello L, Ahnen DJ, Lynch PM. Chemoprevention of hereditary colon cancers: time for new strategies. Nat Rev Gastroenterol Hepatol. 2016 06; 13(6):352-61. PMID: 27095653.
      Citations: 25     Fields:    Translation:HumansAnimals
    58. Samadder NJ, Neklason DW, Boucher KM, Byrne KR, Kanth P, Samowitz W, Jones D, Tavtigian SV, Done MW, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Davis R, Topham MK, Lynch P, Strait E, McKinnon W, Burt RW, Kuwada SK. Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial. JAMA. 2016 Mar 22-29; 315(12):1266-75. PMID: 27002448; PMCID: PMC5003411.
      Citations: 45     Fields:    Translation:Humans
    59. Raju GS, Lum PJ, Ross WA, Thirumurthi S, Miller E, Lynch PM, Lee JH, Bhutani MS, Shafi MA, Weston BR, Pande M, Bresalier RS, Rashid A, Mishra L, Davila ML, Stroehlein JR. Outcome of EMR as an alternative to surgery in patients with complex colon polyps. Gastrointest Endosc. 2016 Aug; 84(2):315-25. PMID: 26859866; PMCID: PMC4949087.
      Citations: 21     Fields:    Translation:Humans
    60. Lynch PM, Morris JS, Wen S, Advani SM, Ross W, Chang GJ, Rodriguez-Bigas M, Raju GS, Ricciardiello L, Iwama T, Rossi BM, Stoffel E, Wise PE, Bertario L, Saunders B, Burt R, Belluzzi A, Ahnen D, Matsubara N, Jespersen N, Clark SK, Erdman SH, Markowitz AJ, Bernstein I, De Haas N, Syngal S, Moeslein G, Pellise M, B?low S. A proposed staging system and stage-specific interventions for familial adenomatous polyposis. Gastrointest Endosc. 2016 Jul; 84(1):115-125.e4. PMID: 26769407; PMCID: PMC5570515.
      Citations: 6     Fields:    Translation:Humans
    61. Katz LH, Burton-Chase AM, Advani S, Fellman B, Polivka KM, Yuan Y, Lynch PM, Peterson SK. Screening adherence and cancer risk perceptions in colorectal cancer survivors with Lynch-like syndrome. Clin Genet. 2016 Mar; 89(3):392-8. PMID: 26272410; PMCID: PMC4935466.
      Citations: 9     Fields:    Translation:Humans
    62. Guindalini RS, Win AK, Gulden C, Lindor NM, Newcomb PA, Haile RW, Raymond V, Stoffel E, Hall M, Llor X, Ukaegbu CI, Solomon I, Weitzel J, Kalady M, Blanco A, Terdiman J, Shuttlesworth GA, Lynch PM, Hampel H, Lynch HT, Jenkins MA, Olopade OI, Kupfer SS. Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome. Gastroenterology. 2015 Nov; 149(6):1446-53. PMID: 26248088; PMCID: PMC4648287.
      Citations: 27     Fields:    Translation:HumansCells
    63. Provenzale D, Jasperson K, Ahnen DJ, Aslanian H, Bray T, Cannon JA, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Gupta S, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Rao MS, Regenbogen SE, Shike M, Steinbach G, Weinberg D, Dwyer MA, Freedman-Cass DA, Darlow S, National comprehensive cancer netwok. Colorectal Cancer Screening, Version 1.2015. J Natl Compr Canc Netw. 2015 Aug; 13(8):959-68; quiz 968. PMID: 26285241.
      Citations: 29     Fields:    Translation:Humans
    64. Lynch PM. The Case for Universal Testing of Colorectal Tumors for Microsatellite Instability: A Coming Mismatch Between Clinical and Laboratory Testing. Dig Dis Sci. 2015 Aug; 60(8):2225-7. PMID: 26123836.
      Citations:    Fields:    Translation:HumansPHPublic Health
    65. Mork ME, You YN, Ying J, Bannon SA, Lynch PM, Rodriguez-Bigas MA, Vilar E. High Prevalence of Hereditary Cancer Syndromes in Adolescents and Young Adults With Colorectal Cancer. J Clin Oncol. 2015 Nov 01; 33(31):3544-9. PMID: 26195711; PMCID: PMC4979241.
      Citations: 61     Fields:    Translation:Humans
    66. Dineen S, Lynch PM, Rodriguez-Bigas MA, Bannon S, Taggart M, Reeves C, Modaro C, Overman M, Chang GJ, Skibber JM, You YN. A Prospective Six Sigma Quality Improvement Trial to Optimize Universal Screening for Genetic Syndrome Among Patients With Young-Onset Colorectal Cancer. J Natl Compr Canc Netw. 2015 Jul; 13(7):865-72. PMID: 26150580.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    67. Raju GS, Lum PJ, Slack RS, Thirumurthi S, Lynch PM, Miller E, Weston BR, Davila ML, Bhutani MS, Shafi MA, Bresalier RS, Dekovich AA, Lee JH, Guha S, Pande M, Blechacz B, Rashid A, Routbort M, Shuttlesworth G, Mishra L, Stroehlein JR, Ross WA. Natural language processing as an alternative to manual reporting of colonoscopy quality metrics. Gastrointest Endosc. 2015 Sep; 82(3):512-9. PMID: 25910665; PMCID: PMC4540652.
      Citations: 34     Fields:    Translation:Humans
    68. Goodenberger ML, Thomas BC, Riegert-Johnson D, Boland CR, Plon SE, Clendenning M, Win AK, Senter L, Lipkin SM, Stadler ZK, Macrae FA, Lynch HT, Weitzel JN, de la Chapelle A, Syngal S, Lynch P, Parry S, Jenkins MA, Gallinger S, Holter S, Aronson M, Newcomb PA, Burnett T, Pichurin P, Hampel H, Terdiman JP, Lu KH, Thibodeau S, Lindor NM, Le Marchand L. PMS2 monoallelic mutation carriers: the known unknown. Genet Med. 2016 Jan; 18(1):13-9. PMID: 25856668; PMCID: PMC4834863.
      Citations: 22     Fields:    Translation:Humans
    69. Lynch PM, Burke CA, Phillips R, Morris JS, Slack R, Wang X, Liu J, Patterson S, Sinicrope FA, Rodriguez-Bigas MA, Half E, Bulow S, Latchford A, Clark S, Ross WA, Malone B, Hasson H, Richmond E, Hawk E. An international randomised trial of celecoxib versus celecoxib plus difluoromethylornithine in patients with familial adenomatous polyposis. Gut. 2016 Feb; 65(2):286-95. PMID: 25792707.
      Citations: 31     Fields:    Translation:Humans
    70. Ross WA, Thirumurthi S, Lynch PM, Rashid A, Pande M, Shafi MA, Lee JH, Raju GS. Detection rates of premalignant polyps during screening colonoscopy: time to revise quality standards? Gastrointest Endosc. 2015 Mar; 81(3):567-74. PMID: 25583558; PMCID: PMC4340745.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    71. Vilar E, Mork ME, Cuddy A, Borras E, Bannon SA, Taggart MW, Ying J, Broaddus RR, Luthra R, Rodriguez-Bigas MA, Lynch PM, You YQ. Role of microsatellite instability-low as a diagnostic biomarker of Lynch syndrome in colorectal cancer. Cancer Genet. 2014 Oct-Dec; 207(10-12):495-502. PMID: 25432668; PMCID: PMC4278939.
      Citations: 6     Fields:    Translation:Humans
    72. Nebgen DR, Lu KH, Rimes S, Keeler E, Broaddus R, Munsell MF, Lynch PM. Combined colonoscopy and endometrial biopsy cancer screening results in women with Lynch syndrome. Gynecol Oncol. 2014 Oct; 135(1):85-9. PMID: 25149916; PMCID: PMC4389779.
      Citations: 5     Fields:    Translation:Humans
    73. Lynch PM. Colorectal cancer screening in the American Indian/Alaska Native population: progress and at least one new challenge. Cancer. 2014 Oct 15; 120(20):3105-7. PMID: 25123576.
      Citations: 1     Fields:    Translation:Humans
    74. Bannon SA, Mork M, Vilar E, Peterson SK, Lu K, Lynch PM, Rodriguez-Bigas MA, You YN. Patient-reported disease knowledge and educational needs in Lynch syndrome: findings of an interactive multidisciplinary patient conference. Hered Cancer Clin Pract. 2014 Feb 05; 12(1):1. PMID: 24499499; PMCID: PMC3922108.
      Citations: 7     
    75. Borras E, Taggart MW, Lynch PM, Vilar E. Establishing a diagnostic road map for MUTYH-associated polyposis. Clin Cancer Res. 2014 Mar 01; 20(5):1061-3. PMID: 24486588; PMCID: PMC3996649.
      Citations: 1     Fields:    Translation:Humans
    76. Lynch HT, Snyder C, Stacey M, Olson B, Peterson SK, Buxbaum S, Shaw T, Lynch PM. Communication and technology in genetic counseling for familial cancer. Clin Genet. 2014 Mar; 85(3):213-22. PMID: 24355094; PMCID: PMC4371849.
      Citations: 10     Fields:    Translation:Humans
    77. Lynch PM. When and how to perform genetic testing for inherited colorectal cancer syndromes. J Natl Compr Canc Netw. 2013 Dec 01; 11(12):1577-83. PMID: 24335689.
      Citations: 3     Fields:    Translation:Humans
    78. Burt RW, Cannon JA, David DS, Early DS, Ford JM, Giardiello FM, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Jasperson K, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Dwyer M, Freedman-Cass D, National comprehensive cancer network. Colorectal cancer screening. J Natl Compr Canc Netw. 2013 Dec 01; 11(12):1538-75. PMID: 24335688.
      Citations: 27     Fields:    Translation:Humans
    79. Burton-Chase AM, Hovick SR, Sun CC, Boyd-Rogers S, Lynch PM, Lu KH, Peterson SK. Gynecologic cancer screening and communication with health care providers in women with Lynch syndrome. Clin Genet. 2014 Aug; 86(2):185-9. PMID: 23906188; PMCID: PMC3909028.
      Citations: 11     Fields:    Translation:Humans
    80. Lynch PM. Colorectal cancer survival by location and microsatellite status: data from the Colon Cancer Family Registries and their implications. Dis Colon Rectum. 2013 Aug; 56(8):935-6. PMID: 23838860.
      Citations:    Fields:    Translation:Humans
    81. de Vos tot Nederveen Cappel WH, Lynch PM, Engel C, Mecklin JP, Vasen HF, J?rvinen HJ. Colorectal surveillance in Lynch syndrome families. Fam Cancer. 2013 Jun; 12(2):261-5. PMID: 23525799.
      Citations: 16     Fields:    Translation:Humans
    82. Lynch HT, Lynch PM. Foreword for "100 years of Lynch syndrome". Fam Cancer. 2013 Jun; 12(2):143-4. PMID: 23661170.
      Citations:    Fields:    Translation:Humans
    83. Lynch HT, Lynch PM. Colorectal cancer: Update on the clinical management of Lynch syndrome. Nat Rev Gastroenterol Hepatol. 2013 Jun; 10(6):323-4. PMID: 23609465.
      Citations: 3     Fields:    Translation:Humans
    84. Wei C, Chen J, Pande M, Lynch PM, Frazier ML. A pilot study comparing protein expression in different segments of the normal colon and rectum and in normal colon versus adenoma in patients with Lynch syndrome. J Cancer Res Clin Oncol. 2013 Jul; 139(7):1241-50. PMID: 23604467; PMCID: PMC3708474.
      Citations: 4     Fields:    Translation:Humans
    85. Raju GS, Vadyala V, Slack R, Krishna SG, Ross WA, Lynch PM, Bresalier RS, Hawk E, Stroehlein JR. Adenoma detection in patients undergoing a comprehensive colonoscopy screening. Cancer Med. 2013 Jun; 2(3):391-402. PMID: 23930215; PMCID: PMC3699850.
      Citations: 11     Fields:    Translation:Humans
    86. Lynch PM. Tumor-based screening for hereditary nonpolyposis colorectal cancer: does age-based selection optimize yield? J Oncol Pract. 2013 Jul; 9(4):180-1. PMID: 23942917; PMCID: PMC3710165.
      Citations:    Fields:    Translation:HumansPHPublic Health
    87. Burton-Chase AM, Hovick SR, Peterson SK, Marani SK, Vernon SW, Amos CI, Frazier ML, Lynch PM, Gritz ER. Changes in screening behaviors and attitudes toward screening from pre-test genetic counseling to post-disclosure in Lynch syndrome families. Clin Genet. 2013 Mar; 83(3):215-20. PMID: 23414081; PMCID: PMC3833250.
      Citations: 12     Fields:    Translation:Humans
    88. Lynch PM. Cancer risks after endometrial cancer in mismatch repair mutation carriers. J Natl Cancer Inst. 2013 Feb 20; 105(4):251-2. PMID: 23385443.
      Citations:    Fields:    Translation:HumansCells
    89. Lynch PM, Morris JS, Ross WA, Rodriguez-Bigas MA, Posadas J, Khalaf R, Weber DM, Sepeda VO, Levin B, Shureiqi I. Global quantitative assessment of the colorectal polyp burden in familial adenomatous polyposis by using a web-based tool. Gastrointest Endosc. 2013 Mar; 77(3):455-63. PMID: 23332604; PMCID: PMC3574220.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    90. Chen J, Pande M, Huang YJ, Wei C, Amos CI, Talseth-Palmer BA, Meldrum CJ, Chen WV, Gorlov IP, Lynch PM, Scott RJ, Frazier ML. Cell cycle-related genes as modifiers of age of onset of colorectal cancer in Lynch syndrome: a large-scale study in non-Hispanic white patients. Carcinogenesis. 2013 Feb; 34(2):299-306. PMID: 23125224; PMCID: PMC3564440.
      Citations: 6     Fields:    Translation:Humans
    91. Pande M, Wei C, Chen J, Amos CI, Lynch PM, Lu KH, Lucio LA, Boyd-Rogers SG, Bannon SA, Mork ME, Frazier ML. Cancer spectrum in DNA mismatch repair gene mutation carriers: results from a hospital based Lynch syndrome registry. Fam Cancer. 2012 Sep; 11(3):441-7. PMID: 22714864; PMCID: PMC3475767.
      Citations: 23     Fields:    Translation:HumansCells
    92. Lynch PM. Current approaches in hereditary nonpolyposis colorectal cancer. J Natl Compr Canc Netw. 2012 Aug; 10(8):961-7. PMID: 22878821.
      Citations:    Fields:    Translation:Humans
    93. Ross W, Lynch P, Raju G, Rodriguez A, Burke T, Hafemeister L, Hawk E, Wu X, Dubois RN, Mishra L. Biomarkers, bundled payments, and colorectal cancer care. Genes Cancer. 2012 Jan; 3(1):16-22. PMID: 22893787; PMCID: PMC3415669.
      Citations: 4     
    94. Jaganmohan S, Lynch PM, Raju RP, Ross WA, Lee JE, Raju GS, Bhutani MS, Fleming JB, Lee JH. Endoscopic management of duodenal adenomas in familial adenomatous polyposis--a single-center experience. Dig Dis Sci. 2012 Mar; 57(3):732-7. PMID: 21960285.
      Citations: 12     Fields:    Translation:Humans
    95. Lynch PM. How helpful is age at colorectal cancer onset in finding HNPCC? Dis Colon Rectum. 2011 May; 54(5):515-7. PMID: 21471750.
      Citations: 3     Fields:    Translation:Humans
    96. Lynch PM. How helpful is age at colorectal cancer onset in finding hereditary nonpolyposis colorectal cancer? Clin Gastroenterol Hepatol. 2011 Jun; 9(6):458-60. PMID: 21440092.
      Citations: 2     Fields:    Translation:Humans
    97. Hu P, Lee CW, Xu JP, Simien C, Fan CL, Tam M, Ramagli L, Brown BW, Lynch P, Frazier ML, Siciliano MJ, Coolbaugh-Murphy M. Microsatellite instability in saliva from patients with hereditary non-polyposis colon cancer and siblings carrying germline mismatch repair gene mutations. Ann Clin Lab Sci. 2011; 41(4):321-30. PMID: 22166501.
      Citations: 3     Fields:    Translation:HumansCells
    98. Huang M, Sun C, Boyd-Rogers S, Burzawa J, Milbourne A, Keeler E, Yzquierdo R, Lynch P, Peterson SK, Lu K. Prospective study of combined colon and endometrial cancer screening in women with lynch syndrome: a patient-centered approach. J Oncol Pract. 2011 Jan; 7(1):43-7. PMID: 21532810; PMCID: PMC3014510.
      Citations: 11     Fields:    
    99. Lynch PM. Hyperplastic polyposis: semantics, biology, and endoscopy. Gut. 2010 Aug; 59(8):1019-21. PMID: 20639248.
      Citations: 8     Fields:    Translation:Humans
    100. Lynch PM. Eicosapentaenoic acid and chemoprevention of FAP. Gut. 2010 Jul; 59(7):871-3. PMID: 20581233.
      Citations: 1     Fields:    Translation:Humans
    101. Lynch PM. Pharmacotherapy for inherited colorectal cancer. Expert Opin Pharmacother. 2010 May; 11(7):1101-8. PMID: 20345333.
      Citations: 2     Fields:    Translation:HumansAnimals
    102. Zhang L, Ren X, Alt E, Bai X, Huang S, Xu Z, Lynch PM, Moyer MP, Wen XF, Wu X. Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. Nature. 2010 Apr 15; 464(7291):1058-61. PMID: 20348907; PMCID: PMC3425353.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    103. Lynch PM, Ayers GD, Hawk E, Richmond E, Eagle C, Woloj M, Church J, Hasson H, Patterson S, Half E, Burke CA. The safety and efficacy of celecoxib in children with familial adenomatous polyposis. Am J Gastroenterol. 2010 Jun; 105(6):1437-43. PMID: 20234350.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    104. Coolbaugh-Murphy MI, Xu JP, Ramagli LS, Ramagli BC, Brown BW, Lynch PM, Hamilton SR, Frazier ML, Siciliano MJ. Microsatellite instability in the peripheral blood leukocytes of HNPCC patients. Hum Mutat. 2010 Mar; 31(3):317-24. PMID: 20052760; PMCID: PMC3544178.
      Citations: 16     Fields:    Translation:HumansCells
    105. Pande M, Lynch PM, Hopper JL, Jenkins MA, Gallinger S, Haile RW, LeMarchand L, Lindor NM, Campbell PT, Newcomb PA, Potter JD, Baron JA, Frazier ML, Amos CI. Smoking and colorectal cancer in Lynch syndrome: results from the Colon Cancer Family Registry and the University of Texas M.D. Anderson Cancer Center. Clin Cancer Res. 2010 Feb 15; 16(4):1331-9. PMID: 20145170; PMCID: PMC2822883.
      Citations: 25     Fields:    Translation:HumansCells
    106. Burt RW, Barthel JS, Dunn KB, David DS, Drelichman E, Ford JM, Giardiello FM, Gruber SB, Halverson AL, Hamilton SR, Ismail MK, Jasperson K, Lazenby AJ, Lynch PM, Martin EW, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, NCCN. NCCN clinical practice guidelines in oncology. Colorectal cancer screening. J Natl Compr Canc Netw. 2010 Jan; 8(1):8-61. PMID: 20064289.
      Citations: 83     Fields:    Translation:Humans
    107. Burton AM, Peterson SK, Marani SK, Vernon SW, Amos CI, Frazier ML, Lynch PM, Gritz ER. Health and lifestyle behaviors among persons at risk of Lynch syndrome. Cancer Causes Control. 2010 Apr; 21(4):513-21. PMID: 20012181; PMCID: PMC8364762.
      Citations: 13     Fields:    Translation:Humans
    108. Lynch PM. The hMSH2 and hMLH1 genes in hereditary nonpolyposis colorectal cancer. Surg Oncol Clin N Am. 2009 Oct; 18(4):611-24. PMID: 19793569.
      Citations: 13     Fields:    Translation:HumansCells
    109. Chen J, Etzel CJ, Amos CI, Zhang Q, Viscofsky N, Lindor NM, Lynch PM, Frazier ML. Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome. Cancer Causes Control. 2009 Nov; 20(9):1769-77. PMID: 19690970; PMCID: PMC3917505.
      Citations: 10     Fields:    Translation:Humans
    110. Lynch HT, Lynch PM, Lanspa SJ, Snyder CL, Lynch JF, Boland CR. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. Clin Genet. 2009 Jul; 76(1):1-18. PMID: 19659756; PMCID: PMC2846640.
      Citations: 270     Fields:    Translation:HumansPHPublic Health
    111. Fatima N, Chelius D, Luke BT, Yi M, Zhang T, Stauffer S, Stephens R, Lynch P, Miller K, Guszczynski T, Boring D, Greenwald P, Ali IU. Label-free global serum proteomic profiling reveals novel celecoxib-modulated proteins in familial adenomatous polyposis patients. Cancer Genomics Proteomics. 2009 Jan-Feb; 6(1):41-9. PMID: 19451089.
      Citations: 7     Fields:    Translation:Humans
    112. Pande M, Amos CI, Osterwisch DR, Chen J, Lynch PM, Broaddus R, Frazier ML. Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome. Cancer Epidemiol Biomarkers Prev. 2008 Sep; 17(9):2393-401. PMID: 18768509; PMCID: PMC3028532.
      Citations: 15     Fields:    Translation:Humans
    113. Bailey AA, Bourke MJ, Williams SJ, Walsh PR, Murray MA, Lee EY, Kwan V, Lynch PM. A prospective randomized trial of cannulation technique in ERCP: effects on technical success and post-ERCP pancreatitis. Endoscopy. 2008 Apr; 40(4):296-301. PMID: 18389448.
      Citations: 66     Fields:    Translation:Humans
    114. Lynch PM. New issues in genetic counseling of hereditary colon cancer. Clin Cancer Res. 2007 Nov 15; 13(22 Pt 2):6857s-61s. PMID: 18006790.
      Citations: 4     Fields:    Translation:Humans
    115. Rosen LS, Bilchik AJ, Beart RW, Benson AB, Chang KJ, Compton CC, Grothey A, Haller DG, Ko CY, Lynch PM, Nelson H, Stamos MJ, Turner RR, Willett CG. New approaches to assessing and treating early-stage colon and rectal cancer: summary statement from 2007 Santa Monica Conference. Clin Cancer Res. 2007 Nov 15; 13(22 Pt 2):6853s-6s. PMID: 18006789.
      Citations: 4     Fields:    Translation:Humans
    116. Lynch HT, Lynch JF, Lynch PM, Attard T. Hereditary colorectal cancer syndromes: molecular genetics, genetic counseling, diagnosis and management. Fam Cancer. 2008; 7(1):27-39. PMID: 17999161.
      Citations: 76     Fields:    Translation:Humans
    117. Lynch PM. Prevention of colorectal cancer in high-risk populations: the increasing role for endoscopy and chemoprevention in FAP and HNPCC. Digestion. 2007; 76(1):68-76. PMID: 17947820.
      Citations: 8     Fields:    Translation:Humans
    118. Patel PR, Mansfield PF, Crane CH, Wu TT, Lee JH, Lynch PM, Morris J, Pisters PW, Feig B, Sunder PK, Izzo JG, Ajani JA. Clinical stage after preoperative chemoradiation is a better predictor of patient outcome than the baseline stage for localized gastric cancer. Cancer. 2007 Sep 01; 110(5):989-95. PMID: 17636525.
      Citations: 6     Fields:    Translation:Humans
    119. Pande M, Chen J, Amos CI, Lynch PM, Broaddus R, Frazier ML. Influence of methylenetetrahydrofolate reductase gene polymorphisms C677T and A1298C on age-associated risk for colorectal cancer in a caucasian lynch syndrome population. Cancer Epidemiol Biomarkers Prev. 2007 Sep; 16(9):1753-9. PMID: 17855693.
      Citations: 7     Fields:    Translation:Humans
    120. Lynch PM. Standards of care in diagnosis and testing for hereditary colon cancer. Fam Cancer. 2008; 7(1):65-72. PMID: 17701450.
      Citations: 6     Fields:    Translation:Humans
    121. Lynch HT, Boland CR, Rodriguez-Bigas MA, Amos C, Lynch JF, Lynch PM. Who should be sent for genetic testing in hereditary colorectal cancer syndromes? J Clin Oncol. 2007 Aug 10; 25(23):3534-42. PMID: 17687158.
      Citations: 26     Fields:    Translation:Humans
    122. Lynch PM. Chemoprevention with special reference to inherited colorectal cancer. Fam Cancer. 2008; 7(1):59-64. PMID: 17680350.
      Citations: 6     Fields:    Translation:Humans
    123. Chen J, Sen S, Amos CI, Wei C, Jones JS, Lynch P, Frazier ML. Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Mol Carcinog. 2007 Apr; 46(4):249-56. PMID: 17219423.
      Citations: 14     Fields:    Translation:Humans
    124. Lynch HT, Lynch JF, Lynch PM. Toward a consensus in molecular diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome). J Natl Cancer Inst. 2007 Feb 21; 99(4):261-3. PMID: 17312298.
      Citations: 19     Fields:    Translation:HumansCells
    125. Ross WA, Alkassab F, Lynch PM, Ayers GD, Ajani J, Lee JH, Bismar M. Evolving role of self-expanding metal stents in the treatment of malignant dysphagia and fistulas. Gastrointest Endosc. 2007 Jan; 65(1):70-6. PMID: 17185082.
      Citations: 34     Fields:    Translation:Humans
    126. Lynch HT, Lynch PM. Clinical selection of candidates for mutational testing for cancer susceptibility. Oncology (Williston Park). 2006 Dec; 20(14 Suppl 10):29-34. PMID: 17354515.
      Citations: 1     Fields:    Translation:Humans
    127. Lynch PM. Is the demonstration of adenoma reduction with rofecoxib a pyrrhic victory? Gastroenterology. 2006 Dec; 131(6):2003-5. PMID: 17188962.
      Citations: 1     Fields:    Translation:Humans
    128. Half EE, Lynch PM. Mutated DNA in the stool--does it have a role in colorectal cancer screening? Nat Clin Pract Gastroenterol Hepatol. 2006 Nov; 3(11):594-5. PMID: 17068491.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    129. Lynch HT, Fusaro RM, Lynch PM. Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer. J Invest Dermatol. 2006 Oct; 126(10):2158-9. PMID: 16983324.
      Citations: 3     Fields:    Translation:HumansCells
    130. Lindor NM, Petersen GM, Hadley DW, Kinney AY, Miesfeldt S, Lu KH, Lynch P, Burke W, Press N. Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review. JAMA. 2006 Sep 27; 296(12):1507-17. PMID: 17003399.
      Citations: 212     Fields:    Translation:Humans
    131. Glebov OK, Rodriguez LM, Lynch P, Patterson S, Lynch H, Nakahara K, Jenkins J, Cliatt J, Humbyrd CJ, Denobile J, Soballe P, Gallinger S, Buchbinder A, Gordon G, Hawk E, Kirsch IR. Celecoxib treatment alters the gene expression profile of normal colonic mucosa. Cancer Epidemiol Biomarkers Prev. 2006 Jul; 15(7):1382-91. PMID: 16835340.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    132. Jones JS, Amos CI, Pande M, Gu X, Chen J, Campos IM, Wei Q, Rodriguez-Bigas M, Lynch PM, Frazier ML. DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset. Cancer Epidemiol Biomarkers Prev. 2006 May; 15(5):886-91. PMID: 16702365.
      Citations: 23     Fields:    Translation:HumansCells
    133. Lynch PM. Current approaches in familial colorectal cancer: a clinical perspective. J Natl Compr Canc Netw. 2006 Apr; 4(4):421-30. PMID: 16569392.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    134. Levin B, Barthel JS, Burt RW, David DS, Ford JM, Giardiello FM, Gruber SB, Halverson AL, Hamilton S, Kohlmann W, Ludwig KA, Lynch PM, Marino C, Martin EW, Mayer RJ, Pasche B, Pirruccello SJ, Rajput A, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Winawer SJ. Colorectal Cancer Screening Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr; 4(4):384-420. PMID: 16569391.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    135. Lynch HT, Boland CR, Gong G, Shaw TG, Lynch PM, Fodde R, Lynch JF, de la Chapelle A. Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications. Eur J Hum Genet. 2006 Apr; 14(4):390-402. PMID: 16479259.
      Citations: 55     Fields:    Translation:Humans
    136. Lynch PM. Does regular use of aspirin reduce the risk of colorectal cancer? Nat Clin Pract Oncol. 2006 Apr; 3(4):186-7. PMID: 16596142.
      Citations:    Fields:    Translation:Humans
    137. Daly MB, Axilbund JE, Bryant E, Buys S, Eng C, Friedman S, Esserman LJ, Farrell CD, Ford JM, Garber JE, Jeter JM, Kohlmann W, Lynch PM, Marcom PK, Nabell LM, Offit K, Osarogiagbon RU, Pasche B, Reiser G, Sutphen R, Weitzel JN, National Comprehensive Cancer Network. Genetic/familial high-risk assessment: breast and ovarian. J Natl Compr Canc Netw. 2006 Feb; 4(2):156-76. PMID: 16451772.
      Citations: 20     Fields:    Translation:Humans
    138. Zecevic M, Amos CI, Gu X, Campos IM, Jones JS, Lynch PM, Rodriguez-Bigas MA, Frazier ML. IGF1 gene polymorphism and risk for hereditary nonpolyposis colorectal cancer. J Natl Cancer Inst. 2006 Jan 18; 98(2):139-43. PMID: 16418517.
      Citations: 22     Fields:    Translation:Humans
    139. Wallace MH, Lynch PM. The current status of chemoprevention in FAP. Fam Cancer. 2006; 5(3):289-94; discussion 295-6. PMID: 16998675.
      Citations: 3     Fields:    Translation:Humans
    140. Shureiqi I, Wu Y, Chen D, Yang XL, Guan B, Morris JS, Yang P, Newman RA, Broaddus R, Hamilton SR, Lynch P, Levin B, Fischer SM, Lippman SM. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. Cancer Res. 2005 Dec 15; 65(24):11486-92. PMID: 16357157; PMCID: PMC1564070.
      Citations: 39     Fields:    Translation:HumansCells
    141. Rohatgi PR, Swisher SG, Correa AM, Wu TT, Liao Z, Komaki R, Walsh G, Vaporciyan A, Lynch PM, Rice DC, Roth JA, Ajani JA. Failure patterns correlate with the proportion of residual carcinoma after preoperative chemoradiotherapy for carcinoma of the esophagus. Cancer. 2005 Oct 01; 104(7):1349-55. PMID: 16130133.
      Citations: 43     Fields:    Translation:Humans
    142. Church J, Berk T, Boman BM, Guillem J, Lynch C, Lynch P, Rodriguez-Bigas M, Rusin L, Weber T, Collaborative Group of the Americas on Inherited Colorectal Cancer. Staging intra-abdominal desmoid tumors in familial adenomatous polyposis: a search for a uniform approach to a troubling disease. Dis Colon Rectum. 2005 Aug; 48(8):1528-34. PMID: 15906134.
      Citations: 19     Fields:    Translation:Humans
    143. Jones JS, Gu X, Lynch PM, Rodriguez-Bigas M, Amos CI, Frazier ML. ATM polymorphism and hereditary nonpolyposis colorectal cancer (HNPCC) age of onset (United States). Cancer Causes Control. 2005 Aug; 16(6):749-53. PMID: 16049814.
      Citations: 5     Fields:    Translation:Humans
    144. Lynch HT, Lynch PM. Molecular screening for the Lynch syndrome--better than family history? N Engl J Med. 2005 May 05; 352(18):1920-2. PMID: 15872208.
      Citations: 9     Fields:    Translation:HumansCells
    145. Gritz ER, Peterson SK, Vernon SW, Marani SK, Baile WF, Watts BG, Amos CI, Frazier ML, Lynch PM. Psychological impact of genetic testing for hereditary nonpolyposis colorectal cancer. J Clin Oncol. 2005 Mar 20; 23(9):1902-10. PMID: 15774782.
      Citations: 49     Fields:    Translation:Humans
    146. Lu KH, Dinh M, Kohlmann W, Watson P, Green J, Syngal S, Bandipalliam P, Chen LM, Allen B, Conrad P, Terdiman J, Sun C, Daniels M, Burke T, Gershenson DM, Lynch H, Lynch P, Broaddus RR. Gynecologic cancer as a "sentinel cancer" for women with hereditary nonpolyposis colorectal cancer syndrome. Obstet Gynecol. 2005 Mar; 105(3):569-74. PMID: 15738026.
      Citations: 84     Fields:    Translation:Humans
    147. Ajani JA, Mansfield PF, Crane CH, Wu TT, Lunagomez S, Lynch PM, Janjan N, Feig B, Faust J, Yao JC, Nivers R, Morris J, Pisters PW. Paclitaxel-based chemoradiotherapy in localized gastric carcinoma: degree of pathologic response and not clinical parameters dictated patient outcome. J Clin Oncol. 2005 Feb 20; 23(6):1237-44. PMID: 15718321.
      Citations: 96     Fields:    Translation:HumansCTClinical Trials
    148. Pentz RD, Peterson SK, Watts B, Vernon SW, Lynch PM, Koehly LM, Gritz ER. Hereditary nonpolyposis colorectal cancer family members' perceptions about the duty to inform and health professionals' role in disseminating genetic information. Genet Test. 2005; 9(3):261-8. PMID: 16225406; PMCID: PMC4007282.
      Citations: 29     Fields:    Translation:Humans
    149. Abraham SC, Park SJ, Cruz-Correa M, Houlihan PS, Half EE, Lynch PM, Wu TT. Frequent CpG island methylation in sporadic and syndromic gastric fundic gland polyps. Am J Clin Pathol. 2004 Nov; 122(5):740-6. PMID: 15491970.
      Citations: 5     Fields:    Translation:HumansCells
    150. Jones JS, Chi X, Gu X, Lynch PM, Amos CI, Frazier ML. p53 polymorphism and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Clin Cancer Res. 2004 Sep 01; 10(17):5845-9. PMID: 15355915.
      Citations: 27     Fields:    Translation:HumansCells
    151. Broaddus RR, Lynch PM, Lu KH, Luthra R, Michelson SJ. Unusual tumors associated with the hereditary nonpolyposis colorectal cancer syndrome. Mod Pathol. 2004 Aug; 17(8):981-9. PMID: 15143336.
      Citations: 34     Fields:    Translation:HumansCells
    152. Ajani JA, Mansfield PF, Janjan N, Morris J, Pisters PW, Lynch PM, Feig B, Myerson R, Nivers R, Cohen DS, Gunderson LL. Multi-institutional trial of preoperative chemoradiotherapy in patients with potentially resectable gastric carcinoma. J Clin Oncol. 2004 Jul 15; 22(14):2774-80. PMID: 15254045.
      Citations: 117     Fields:    Translation:HumansCTClinical Trials
    153. Agarwal B, Swisher S, Ajani J, Kelly K, Fanning C, Komaki RR, Putnam JB, Abu-Hamda E, Molke KL, Walsh GL, Correa AM, Ho L, Liao Z, Lynch PM, Rice DC, Smythe WR, Stevens CW, Vaporciyan AA, Yao J, Roth JA. Endoscopic ultrasound after preoperative chemoradiation can help identify patients who benefit maximally after surgical esophageal resection. Am J Gastroenterol. 2004 Jul; 99(7):1258-66. PMID: 15233663.
      Citations: 7     Fields:    Translation:Humans
    154. Ajani JA, Walsh G, Komaki R, Morris J, Swisher SG, Putnam JB, Lynch PM, Wu TT, Smythe R, Vaporciyan A, Faust J, Cohen DS, Nivers R, Roth JA. Preoperative induction of CPT-11 and cisplatin chemotherapy followed by chemoradiotherapy in patients with locoregional carcinoma of the esophagus or gastroesophageal junction. Cancer. 2004 Jun 01; 100(11):2347-54. PMID: 15160337.
      Citations: 19     Fields:    Translation:Humans
    155. Sinicrope FA, Half E, Morris JS, Lynch PM, Morrow JD, Levin B, Hawk ET, Cohen DS, Ayers GD, Stephens LC, Familial Adenomatous Polyposis Study Group. Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in familial adenomatous polyposis patients. Cancer Epidemiol Biomarkers Prev. 2004 Jun; 13(6):920-7. PMID: 15184247.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    156. Amos CI, Keitheri-Cheteri MB, Sabripour M, Wei C, McGarrity TJ, Seldin MF, Nations L, Lynch PM, Fidder HH, Friedman E, Frazier ML. Genotype-phenotype correlations in Peutz-Jeghers syndrome. J Med Genet. 2004 May; 41(5):327-33. PMID: 15121768; PMCID: PMC1735760.
      Citations: 57     Fields:    Translation:HumansCells
    157. Xiao Z, Luke BT, Izmirlian G, Umar A, Lynch PM, Phillips RK, Patterson S, Conrads TP, Veenstra TD, Greenwald P, Hawk ET, Ali IU. Serum proteomic profiles suggest celecoxib-modulated targets and response predictors. Cancer Res. 2004 Apr 15; 64(8):2904-9. PMID: 15087410.
      Citations: 7     Fields:    Translation:Humans
    158. Cotton PB, Durkalski VL, Pineau BC, Palesch YY, Mauldin PD, Hoffman B, Vining DJ, Small WC, Affronti J, Rex D, Kopecky KK, Ackerman S, Burdick JS, Brewington C, Turner MA, Zfass A, Wright AR, Iyer RB, Lynch P, Sivak MV, Butler H. Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia. JAMA. 2004 Apr 14; 291(14):1713-9. PMID: 15082698.
      Citations: 119     Fields:    Translation:HumansCTClinical Trials
    159. Jones JS, Gu X, Campos IM, Lynch PM, Amos CI, Frazier ML. GSTM1 polymorphism does not affect hereditary nonpolyposis colorectal cancer age of onset. Cancer Epidemiol Biomarkers Prev. 2004 Apr; 13(4):676-8. PMID: 15066938.
      Citations: 2     Fields:    Translation:Humans
    160. Yang Q, Cleary KR, Yao JC, Swisher SG, Roth JA, Lynch PM, Komaki R, Ajani JA, Rashid A, Hamilton SR, Wu TT. Significance of post-chemoradiation biopsy in predicting residual esophageal carcinoma in the surgical specimen. Dis Esophagus. 2004; 17(1):38-43. PMID: 15209739.
      Citations: 13     Fields:    Translation:Humans
    161. Abu-Hamda EM, Hattab EM, Lynch PM. Small bowel tumors. Curr Gastroenterol Rep. 2003 Oct; 5(5):386-93. PMID: 12959719.
      Citations: 5     Fields:    Translation:Humans
    162. Frazier ML, Xi L, Zong J, Viscofsky N, Rashid A, Wu EF, Lynch PM, Amos CI, Issa JP. Association of the CpG island methylator phenotype with family history of cancer in patients with colorectal cancer. Cancer Res. 2003 Aug 15; 63(16):4805-8. PMID: 12941799.
      Citations: 34     Fields:    Translation:HumansCells
    163. Glebov OK, Rodriguez LM, Nakahara K, Jenkins J, Cliatt J, Humbyrd CJ, DeNobile J, Soballe P, Simon R, Wright G, Lynch P, Patterson S, Lynch H, Gallinger S, Buchbinder A, Gordon G, Hawk E, Kirsch IR. Distinguishing right from left colon by the pattern of gene expression. Cancer Epidemiol Biomarkers Prev. 2003 Aug; 12(8):755-62. PMID: 12917207.
      Citations: 117     Fields:    Translation:Humans
    164. Lynch HT, Cristofaro G, Rozen P, Vasen H, Lynch P, Mecklin JP, St John J. History of the International Collaborative Group on Hereditary Non Polyposis Colorectal Cancer. Fam Cancer. 2003; 2(Suppl 1):3-5. PMID: 14574154.
      Citations: 9     Fields:    Translation:Humans
    165. Wright EP, Kiely MA, Lynch P, Cull A, Selby PJ. Social problems in oncology. Br J Cancer. 2002 Nov 04; 87(10):1099-104. PMID: 12402148; PMCID: PMC2376184.
      Citations: 27     Fields:    Translation:Humans
    166. Esaki M, Matsumoto T, Mizuno M, Kobori Y, Yoshimura R, Yao T, Iida M. Effect of sulindac treatment for attenuated familial adenomatous polyposis with a new germline APC mutation at codon 161: report of a case. Dis Colon Rectum. 2002 Oct; 45(10):1397-402; discussion 1402-6. PMID: 12394442.
      Citations: 3     Fields:    Translation:Humans
    167. Su LK, Kohlmann W, Ward PA, Lynch PM. Different familial adenomatous polyposis phenotypes resulting from deletions of the entire APC exon 15. Hum Genet. 2002 Jul; 111(1):88-95. PMID: 12136240.
      Citations: 7     Fields:    Translation:HumansCells
    168. Phillips RK, Wallace MH, Lynch PM, Hawk E, Gordon GB, Saunders BP, Wakabayashi N, Shen Y, Zimmerman S, Godio L, Rodrigues-Bigas M, Su LK, Sherman J, Kelloff G, Levin B, Steinbach G, FAP Study Group. A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis. Gut. 2002 Jun; 50(6):857-60. PMID: 12010890; PMCID: PMC1773237.
      Citations: 116     Fields:    Translation:HumansCTClinical Trials
    169. Lynch PM. Screening colonoscopy for family history of colorectal cancer: a growing consensus. Ann Surg Oncol. 2002 Jun; 9(5):425-7. PMID: 12052750.
      Citations:    Fields:    Translation:HumansPHPublic Health
    170. Howe JR, Shellnut J, Wagner B, Ringold JC, Sayed MG, Ahmed AF, Lynch PM, Amos CI, Sistonen P, Aaltonen LA. Common deletion of SMAD4 in juvenile polyposis is a mutational hotspot. Am J Hum Genet. 2002 May; 70(5):1357-62. PMID: 11920286; PMCID: PMC447611.
      Citations: 15     Fields:    Translation:HumansCells
    171. Yao JC, Schnirer II, Reddy S, Chiang S, Najam A, Yu C, Giacco G, Hess K, Rashid A, Xie K, Lynch P, Ajani JA. Effects of sex and racial/ethnic group on the pattern of gastric cancer localization. Gastric Cancer. 2002; 5(4):208-12. PMID: 12491078.
      Citations: 22     Fields:    Translation:Humans
    172. Kong S, Wei Q, Amos CI, Lynch PM, Levin B, Zong J, Frazier ML. Cyclin D1 polymorphism and increased risk of colorectal cancer at young age. J Natl Cancer Inst. 2001 Jul 18; 93(14):1106-8. PMID: 11459873.
      Citations: 26     Fields:    Translation:Humans
    173. Ajani JA, Komaki R, Putnam JB, Walsh G, Nesbitt J, Pisters PW, Lynch PM, Vaporciyan A, Smythe R, Lahoti S, Raijman I, Swisher S, Martin FD, Roth JA. A three-step strategy of induction chemotherapy then chemoradiation followed by surgery in patients with potentially resectable carcinoma of the esophagus or gastroesophageal junction. Cancer. 2001 Jul 15; 92(2):279-86. PMID: 11466680.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    174. Janjan NA, Crane C, Feig BW, Cleary K, Dubrow R, Curley S, Vauthey JN, Lynch P, Ellis LM, Wolff R, Lenzi R, Abbruzzese J, Pazdur R, Hoff PM, Allen P, Brown T, Skibber J. Improved overall survival among responders to preoperative chemoradiation for locally advanced rectal cancer. Am J Clin Oncol. 2001 Apr; 24(2):107-12. PMID: 11319280.
      Citations: 77     Fields:    Translation:HumansCTClinical Trials
    175. Lynch PM. COX-2 inhibition in clinical cancer prevention. Oncology (Williston Park). 2001 Mar; 15(3 Suppl 5):21-6. PMID: 11301836.
      Citations: 3     Fields:    Translation:Humans
    176. Frazier ML, O'Donnell FT, Kong S, Gu X, Campos I, Luthra R, Lynch PM, Amos CI. Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes. Cancer Res. 2001 Feb 15; 61(4):1269-71. PMID: 11245417.
      Citations: 20     Fields:    Translation:HumansCells
    177. Wu G, Wu W, Hegde M, Fawkner M, Chong B, Love D, Su LK, Lynch P, Snow K, Richards CS. Detection of sequence variations in the adenomatous polyposis coli (APC) gene using denaturing high-performance liquid chromatography. Genet Test. 2001; 5(4):281-90. PMID: 11960572.
      Citations: 9     Fields:    Translation:Humans
    178. Crane CH, Janjan NA, Abbruzzese JL, Curley S, Vauthey J, Sawaf HB, Dubrow R, Allen P, Ellis LM, Hoff P, Wolff RA, Lenzi R, Brown TD, Lynch P, Cleary K, Rich TA, Skibber J. Effective pelvic symptom control using initial chemoradiation without colostomy in metastatic rectal cancer. Int J Radiat Oncol Biol Phys. 2001 Jan 01; 49(1):107-16. PMID: 11163503.
      Citations: 15     Fields:    Translation:Humans
    179. Komaki R, Janjan NA, Ajani JA, Lynch PM, Fairweather JS, Raijman I, Blumenshein GR, Ho L, Pisters PW, Feig BW, Walsh GL, Pazdur R. Phase I study of irinotecan and concurrent radiation therapy for upper GI tumors. Oncology (Williston Park). 2000 Dec; 14(12 Suppl 14):34-7. PMID: 11200147.
      Citations: 5     Fields:    Translation:Humans
    180. Precancerous lesions of the digestive tract. The 18th Annual Symposium of the European Cancer Prevention Organization. Maastricht, The Netherlands. 12-14 October 2000. Abstracts. Eur J Cancer Prev. 2000 Dec; 9(6):443-63. PMID: 11263399.
      Citations:    Fields:    Translation:Humans
    181. Frazier ML, Su LK, Amos CI, Lynch PM. Current applications of genetic technology in predisposition testing and microsatellite instability assays. J Clin Oncol. 2000 Nov 01; 18(21 Suppl):70S-4S. PMID: 11060331.
      Citations: 2     Fields:    Translation:HumansCells
    182. Su LK, Barnes CJ, Yao W, Qi Y, Lynch PM, Steinbach G. Inactivation of germline mutant APC alleles by attenuated somatic mutations: a molecular genetic mechanism for attenuated familial adenomatous polyposis. Am J Hum Genet. 2000 Sep; 67(3):582-90. PMID: 10924409; PMCID: PMC1287518.
      Citations: 18     Fields:    Translation:Humans
    183. Steinbach G, Lynch PM, Phillips RK, Wallace MH, Hawk E, Gordon GB, Wakabayashi N, Saunders B, Shen Y, Fujimura T, Su LK, Levin B, Godio L, Patterson S, Rodriguez-Bigas MA, Jester SL, King KL, Schumacher M, Abbruzzese J, DuBois RN, Hittelman WN, Zimmerman S, Sherman JW, Kelloff G. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med. 2000 Jun 29; 342(26):1946-52. PMID: 10874062.
      Citations: 540     Fields:    Translation:HumansCTClinical Trials
    184. Brown RL, Pollock AN, Couchman KG, Hodges M, Hutchinson DO, Waaka R, Lynch P, McCarthy TV, Stowell KM. A novel ryanodine receptor mutation and genotype-phenotype correlation in a large malignant hyperthermia New Zealand Maori pedigree. Hum Mol Genet. 2000 Jun 12; 9(10):1515-24. PMID: 10888602.
      Citations: 16     Fields:    Translation:HumansCells
    185. Janjan NA, Crane CN, Feig BW, Cleary K, Dubrow R, Curley SA, Ellis LM, Vauthey J, Lenzi R, Lynch P, Wolff R, Brown T, Pazdur R, Abbruzzese J, Hoff PM, Allen P, Brown B, Skibber J. Prospective trial of preoperative concomitant boost radiotherapy with continuous infusion 5-fluorouracil for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2000 Jun 01; 47(3):713-8. PMID: 10837955.
      Citations: 22     Fields:    Translation:Humans
    186. Lynch P. If aggressive surveillance in hereditary nonpolyposis colorectal cancer is now state of the art, are there any challenges left? Gastroenterology. 2000 May; 118(5):969-71. PMID: 10784597.
      Citations: 1     Fields:    Translation:Humans
    187. Ibrahim NK, Sahin AA, Dubrow RA, Lynch PM, Boehnke-Michaud L, Valero V, Buzdar AU, Hortobagyi GN. Colitis associated with docetaxel-based chemotherapy in patients with metastatic breast cancer. Lancet. 2000 Jan 22; 355(9200):281-3. PMID: 10675076.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    188. Kong S, Amos CI, Luthra R, Lynch PM, Levin B, Frazier ML. Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer. Cancer Res. 2000 Jan 15; 60(2):249-52. PMID: 10667569.
      Citations: 41     Fields:    Translation:HumansCells
    189. Su LK, Steinbach G, Sawyer JC, Hindi M, Ward PA, Lynch PM. Genomic rearrangements of the APC tumor-suppressor gene in familial adenomatous polyposis. Hum Genet. 2000 Jan; 106(1):101-7. PMID: 10982189.
      Citations: 25     Fields:    Translation:HumansCells
    190. Lynch PM. Clinical challenges in management of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer. Cancer. 1999 Dec 01; 86(11 Suppl):2533-9. PMID: 10630179.
      Citations: 2     Fields:    Translation:Humans
    191. Roth S, Sistonen P, Salovaara R, Hemminki A, Loukola A, Johansson M, Avizienyte E, Cleary KA, Lynch P, Amos CI, Kristo P, Mecklin JP, Kellokumpu I, Aaltonen LA, J?rvinen H. SMAD genes in juvenile polyposis. Genes Chromosomes Cancer. 1999 Sep; 26(1):54-61. PMID: 10441006.
      Citations: 17     Fields:    Translation:HumansCells
    192. Ajani JA, Mansfield PF, Lynch PM, Pisters PW, Feig B, Dumas P, Evans DB, Raijman I, Hargraves K, Curley S, Ota DM. Enhanced staging and all chemotherapy preoperatively in patients with potentially resectable gastric carcinoma. J Clin Oncol. 1999 Aug; 17(8):2403-11. PMID: 10561303.
      Citations: 30     Fields:    Translation:Humans
    193. Sinicrope FA, Lemoine M, Xi L, Lynch PM, Cleary KR, Shen Y, Frazier ML. Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers. Gastroenterology. 1999 Aug; 117(2):350-8. PMID: 10419916.
      Citations: 36     Fields:    Translation:HumansCells
    194. Steinbach G, Ford R, Glober G, Sample D, Hagemeister FB, Lynch PM, McLaughlin PW, Rodriguez MA, Romaguera JE, Sarris AH, Younes A, Luthra R, Manning JT, Johnson CM, Lahoti S, Shen Y, Lee JE, Winn RJ, Genta RM, Graham DY, Cabanillas FF. Antibiotic treatment of gastric lymphoma of mucosa-associated lymphoid tissue. An uncontrolled trial. Ann Intern Med. 1999 Jul 20; 131(2):88-95. PMID: 10419446.
      Citations: 52     Fields:    Translation:HumansCells
    195. Janjan NA, Khoo VS, Abbruzzese J, Pazdur R, Dubrow R, Cleary KR, Allen PK, Lynch PM, Glober G, Wolff R, Rich TA, Skibber J. Tumor downstaging and sphincter preservation with preoperative chemoradiation in locally advanced rectal cancer: the M. D. Anderson Cancer Center experience. Int J Radiat Oncol Biol Phys. 1999 Jul 15; 44(5):1027-38. PMID: 10421535.
      Citations: 124     Fields:    Translation:Humans
    196. Janjan NA, Abbruzzese J, Pazdur R, Khoo VS, Cleary K, Dubrow R, Ajani J, Rich TA, Goswitz MS, Evetts PA, Allen PK, Lynch PM, Skibber JM. Prognostic implications of response to preoperative infusional chemoradiation in locally advanced rectal cancer. Radiother Oncol. 1999 May; 51(2):153-60. PMID: 10435807.
      Citations: 25     Fields:    Translation:Humans
    197. Frazier ML, Sinicrope FA, Amos CI, Cleary KR, Lynch PM, Levin B, Luthra R. Loci for efficient detection of microsatellite instability in hereditary non-polyposis colorectal cancer. Oncol Rep. 1999 May-Jun; 6(3):497-505. PMID: 10203581.
      Citations: 5     Fields:    Translation:HumansCells
    198. Lin X, Choi JH, Lynch P, Xi L, Wu E, Frazier ML. Reduction in hMSH2 mRNA levels by premature translation termination: implications for mutation screening in hereditary nonpolyposis colorectal cancer. Dig Dis Sci. 1999 Mar; 44(3):553-9. PMID: 10080150.
      Citations:    Fields:    Translation:HumansCells
    199. Lynch HT, Paulson J, Severin M, Lynch J, Lynch P. Failure to diagnose hereditary colorectal cancer and its medicolegal implications: a hereditary nonpolyposis colorectal cancer case. Dis Colon Rectum. 1999 Jan; 42(1):31-5. PMID: 10211517.
      Citations: 3     Fields:    Translation:Humans
    200. Raijman I, Siddique I, Ajani J, Lynch P. Palliation of malignant dysphagia and fistulae with coated expandable metal stents: experience with 101 patients. Gastrointest Endosc. 1998 Aug; 48(2):172-9. PMID: 9717783.
      Citations: 35     Fields:    Translation:Humans
    201. Vernon SW, Gritz ER, Peterson SK, Amos CI, Baile WF, Perz CA, Lynch PM. Design and methodology of a study of psychosocial aspects of genetic testing for hereditary colorectal cancer. Ann N Y Acad Sci. 1997 Dec 29; 833:190-4. PMID: 9616754.
      Citations: 1     Fields:    Translation:HumansCells
    202. Raijman I, Lynch P. Coated expandable esophageal stents in the treatment of digestive-respiratory fistulas. Am J Gastroenterol. 1997 Dec; 92(12):2188-91. PMID: 9399749.
      Citations: 5     Fields:    Translation:Humans
    203. Raijman I, Siddique I, Lynch P. Does chemoradiation therapy increase the incidence of complications with self-expanding coated stents in the management of malignant esophageal strictures? Am J Gastroenterol. 1997 Dec; 92(12):2192-6. PMID: 9399750.
      Citations: 10     Fields:    Translation:Humans
    204. Amos CI, Bali D, Thiel TJ, Anderson JP, Gourley I, Frazier ML, Lynch PM, Luchtefeld MA, Young A, McGarrity TJ, Seldin MF. Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p. Cancer Res. 1997 Sep 01; 57(17):3653-6. PMID: 9288765.
      Citations: 20     Fields:    Translation:HumansCells
    205. Gilson E. Benefits and risks of screening mammography in women with BRCA1 and BRCA2 mutations. JAMA. 1997 Jul 23-30; 278(4):289-90; author reply 290. PMID: 9228429.
      Citations:    Fields:    Translation:Humans
    206. Konishi H, Steinbach G, Terry NH, Fujita K, Lee JJ, Ruifrok A, Spaulding D, Lynch PM, Dubin JA, Andreeff M, Goodacre AM, Hattori T, Hittelman WN. S phase determination in intact colonic crypts by histone H3 messenger RNA in situ hybridization and confocal microscopy. Cancer Epidemiol Biomarkers Prev. 1997 Jul; 6(7):531-6. PMID: 9232341.
      Citations: 1     Fields:    Translation:AnimalsCells
    207. Burke W, Daly M, Garber J, Botkin J, Kahn MJ, Lynch P, McTiernan A, Offit K, Perlman J, Petersen G, Thomson E, Varricchio C. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. II. BRCA1 and BRCA2. Cancer Genetics Studies Consortium. JAMA. 1997 Mar 26; 277(12):997-1003. PMID: 9091675.
      Citations: 153     Fields:    Translation:Humans
    208. Burke W, Petersen G, Lynch P, Botkin J, Daly M, Garber J, Kahn MJ, McTiernan A, Offit K, Thomson E, Varricchio C. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. I. Hereditary nonpolyposis colon cancer. Cancer Genetics Studies Consortium. JAMA. 1997 Mar 19; 277(11):915-9. PMID: 9062331.
      Citations: 72     Fields:    Translation:Humans
    209. Vernon SW, Gritz ER, Peterson SK, Amos CI, Perz CA, Baile WF, Lynch PM. Correlates of psychologic distress in colorectal cancer patients undergoing genetic testing for hereditary colon cancer. Health Psychol. 1997 Jan; 16(1):73-86. PMID: 9028817.
      Citations: 24     Fields:    Translation:Humans
    210. Yin J, Kong D, Wang S, Zou TT, Souza RF, Smolinski KN, Lynch PM, Hamilton SR, Sugimura H, Powell SM, Young J, Abraham JM, Meltzer SJ. Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas. Hum Mutat. 1997; 10(6):474-8. PMID: 9401011.
      Citations: 13     Fields:    Translation:HumansCells
    211. Souza RF, Appel R, Yin J, Wang S, Smolinski KN, Abraham JM, Zou TT, Shi YQ, Lei J, Cottrell J, Cymes K, Biden K, Simms L, Leggett B, Lynch PM, Frazier M, Powell SM, Harpaz N, Sugimura H, Young J, Meltzer SJ. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat Genet. 1996 Nov; 14(3):255-7. PMID: 8896552.
      Citations: 86     Fields:    Translation:HumansCells
    212. Roubein LD, Lynch P, Glober G, Sinicrope FA. Interobserver variability in endoscopic ultrasonography: a prospective evaluation. Gastrointest Endosc. 1996 Nov; 44(5):573-7. PMID: 8934164.
      Citations: 5     Fields:    Translation:Humans
    213. Patt YZ, Jones DV, Hoque A, Lozano R, Markowitz A, Raijman I, Lynch P, Charnsangavej C. Phase II trial of intravenous flourouracil and subcutaneous interferon alfa-2b for biliary tract cancer. J Clin Oncol. 1996 Aug; 14(8):2311-5. PMID: 8708722.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    214. Jeon HM, Lynch PM, Howard L, Ajani J, Levin B, Frazier ML. Mutation of the hMSH2 gene in two families with hereditary nonpolyposis colorectal cancer. Hum Mutat. 1996; 7(4):327-33. PMID: 8723682.
      Citations: 1     Fields:    Translation:Humans
    215. Terry NH, Meistrich ML, Roubein LD, Lynch PM, Dubrow RA, Rich TA. Cellular kinetics in rectal cancer. Br J Cancer. 1995 Aug; 72(2):435-41. PMID: 7640229; PMCID: PMC2033968.
      Citations: 8     Fields:    Translation:HumansCells
    216. Rich TA, Skibber JM, Ajani JA, Buchholz DJ, Cleary KR, Dubrow RA, Levin B, Lynch PM, Meterissian SH, Roubein LD, et al. Preoperative infusional chemoradiation therapy for stage T3 rectal cancer. Int J Radiat Oncol Biol Phys. 1995 Jul 15; 32(4):1025-9. PMID: 7607922.
      Citations: 29     Fields:    Translation:Humans
    217. Kim YH, Ajani JA, Ota DM, Lynch P, Roth JA. Value of serial carcinoembryonic antigen levels in patients with resectable adenocarcinoma of the esophagus and stomach. Cancer. 1995 Jan 15; 75(2):451-6. PMID: 7812915.
      Citations: 5     Fields:    Translation:Humans
    218. Ajani JA, Roth JA, Putnam JB, Walsh G, Lynch PM, Roubein LD, Ryan MB, Natrajan G, Gould P. Feasibility of five courses of pre-operative chemotherapy in patients with resectable adenocarcinoma of the oesophagus or gastrooesophageal junction. Eur J Cancer. 1995; 31A(5):665-70. PMID: 7640036.
      Citations: 2     Fields:    Translation:Humans
    219. Lynch P. Biology of gastric cancer: gastritis-metaplasia-dysplasia sequence, role of H Pylori, and molecular correlates of tumor progression. J Infus Chemother. 1995; 5(3):93-6. PMID: 8528971.
      Citations:    Fields:    Translation:HumansCells
    220. Parsons R, Sistonen P, Aaltonen LA, Leach FS, Hamilton SR, Watson P, Bronson E, Fusaro R, Nystr?m-Lahti M, Pylkk?nen L, et al. Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage. Am J Hum Genet. 1994 Oct; 55(4):659-65. PMID: 7942843; PMCID: PMC1918295.
      Citations: 25     Fields:    Translation:HumansCells
    221. Lynch HT, Drouhard T, Lanspa S, Smyrk T, Lynch P, Lynch J, Vogelstein B, Sistonen P, Nystr?m-Lahti M, Peltom?ki P, et al. Mutation of an mutL homologue in a Navajo family with hereditary nonpolyposis colorectal cancer. J Natl Cancer Inst. 1994 Sep 21; 86(18):1417-9. PMID: 8072036.
      Citations: 6     Fields:    Translation:Humans
    222. Ajani JA, Ilson DH, Daugherty K, Pazdur R, Lynch PM, Kelsen DP. Activity of taxol in patients with squamous cell carcinoma and adenocarcinoma of the esophagus. J Natl Cancer Inst. 1994 Jul 20; 86(14):1086-91. PMID: 7912736.
      Citations: 66     Fields:    Translation:HumansCTClinical Trials
    223. Lynch PM. Surveillance and treatment of hereditary non-polyposis colorectal cancer. Anticancer Res. 1994 Jul-Aug; 14(4B):1641-6. PMID: 7979200.
      Citations:    Fields:    Translation:HumansPHPublic Health
    224. Lynch PM. Hereditary nonpolyposis colorectal carcinoma (HNPCC): clinical application of molecular diagnostic testing. Ann Med. 1994 Jun; 26(3):221-8. PMID: 8074841.
      Citations: 1     Fields:    Translation:Humans
    225. Spirio L, Olschwang S, Groden J, Robertson M, Samowitz W, Joslyn G, Gelbert L, Thliveris A, Carlson M, Otterud B, et al. Alleles of the APC gene: an attenuated form of familial polyposis. Cell. 1993 Dec 03; 75(5):951-7. PMID: 8252630.
      Citations: 121     Fields:    Translation:HumansCells
    226. Roubein LD, DuBrow R, David C, Lynch P, Fornage B, Ajani J, Roth J, Levin B. Endoscopic ultrasonography in the quantitative assessment of response to chemotherapy in patients with adenocarcinoma of the esophagus and esophagogastric junction. Endoscopy. 1993 Nov; 25(9):587-91. PMID: 8119209.
      Citations: 2     Fields:    Translation:Humans
    227. Lynch HT, Smyrk TC, Lanspa SJ, Jenkins JX, Lynch PM, Cavalieri J, Lynch JF. Upper gastrointestinal manifestations in families with hereditary flat adenoma syndrome. Cancer. 1993 May 01; 71(9):2709-14. PMID: 8385563.
      Citations: 12     Fields:    Translation:Humans
    228. Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, Cavalieri RJ, Boland CR. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology. 1993 May; 104(5):1535-49. PMID: 8482467.
      Citations: 181     Fields:    Translation:Humans
    229. Ender B, Lynch P, Kim YH, Inamdar NV, Cleary KR, Frazier ML. Overexpression of an elongation factor-1 gamma-hybridizing RNA in colorectal adenomas. Mol Carcinog. 1993; 7(1):18-20. PMID: 8382068.
      Citations: 6     Fields:    Translation:HumansCells
    230. Vasen HF, Mecklin JP, Watson P, Utsunomiya J, Bertario L, Lynch P, Svendsen LB, Cristofaro G, Khan PM, M?ller H, et al. Surveillance in hereditary nonpolyposis colorectal cancer: an international cooperative study of 165 families. The International Collaborative Group on HNPCC. Dis Colon Rectum. 1993 Jan; 36(1):1-4. PMID: 8416772.
      Citations: 20     Fields:    Translation:HumansPHPublic Health
    231. Wargovich MJ, Isbell G, Shabot M, Winn R, Lanza F, Hochman L, Larson E, Lynch P, Roubein L, Levin B. Calcium supplementation decreases rectal epithelial cell proliferation in subjects with sporadic adenoma. Gastroenterology. 1992 Jul; 103(1):92-7. PMID: 1612362.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    232. Spirio L, Otterud B, Stauffer D, Lynch H, Lynch P, Watson P, Lanspa S, Smyrk T, Cavalieri J, Howard L, et al. Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus. Am J Hum Genet. 1992 Jul; 51(1):92-100. PMID: 1319115; PMCID: PMC1682871.
      Citations: 25     Fields:    Translation:Humans
    233. Morris L, Lynch PM, Gleason WA, Schauder C, Pinkel D, Duvic M. Blue rubber bleb nevus syndrome: laser photocoagulation of colonic hemangiomas in a child with microcytic anemia. Pediatr Dermatol. 1992 Jun; 9(2):91-4. PMID: 1603744.
      Citations: 8     Fields:    Translation:Humans
    234. Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch PM, Jenkins JX, Rouse J, Cavalieri J, Howard L, Lynch J. Hereditary flat adenoma syndrome: a variant of familial adenomatous polyposis? Dis Colon Rectum. 1992 May; 35(5):411-21. PMID: 1314729.
      Citations: 14     Fields:    Translation:HumansCells
    235. Daneker GW, Carlson GW, Hohn DC, Lynch P, Roubein L, Levin B. Endoscopic laser recanalization is effective for prevention and treatment of obstruction in sigmoid and rectal cancer. Arch Surg. 1991 Nov; 126(11):1348-52. PMID: 1720949.
      Citations: 2     Fields:    Translation:Humans
    236. Lynch HT, Smyrk T, Watson P, Lanspa SJ, Boman BM, Lynch PM, Lynch JF, Cavalieri J. Hereditary colorectal cancer. Semin Oncol. 1991 Aug; 18(4):337-66. PMID: 1677781.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    237. Lynch PM, Wargovich MJ, Lynch HT, Palmer C, Lanspa S, Drouhard T, Lynch J. A follow-up study of colonic epithelial proliferation as a biomarker ina Native-American family with hereditary nonpolyposis colon cancer. J Natl Cancer Inst. 1991 Jul 03; 83(13):951-4. PMID: 2067038.
      Citations: 3     Fields:    Translation:HumansCells
    238. Wargovich MJ, Lynch PM, Levin B. Modulating effects of calcium in animal models of colon carcinogenesis and short-term studies in subjects at increased risk for colon cancer. Am J Clin Nutr. 1991 07; 54(1 Suppl):202S-205S. PMID: 2053562.
      Citations: 6     Fields:    Translation:HumansAnimals
    239. Roubein LD, David C, DuBrow R, Faintuch J, Lynch P, Fornage B, Levin B. Endoscopic ultrasonography in staging rectal cancer. Am J Gastroenterol. 1990 Oct; 85(10):1391-4. PMID: 2220734.
      Citations: 3     Fields:    Translation:Humans
    240. Lynch HT, Smyrk TC, Lanspa SJ, Lynch PM, Watson P, Strayhorn PC, Bronson EK, Lynch JF, Priluck IA, Appelman HD. Phenotypic variation in colorectal adenoma/cancer expression in two families. Hereditary flat adenoma syndrome. Cancer. 1990 Sep 01; 66(5):909-15. PMID: 2386918.
      Citations: 8     Fields:    Translation:Humans
    241. Lynch HT, Smyrk TC, Lynch PM, Lanspa SJ, Boman BM, Ens J, Lynch JF, Strayhorn P, Carmody T, Cristofaro G. Adenocarcinoma of the small bowel in lynch syndrome II. Cancer. 1989 Nov 15; 64(10):2178-83. PMID: 2804907.
      Citations: 9     Fields:    Translation:Humans
    242. Lynch P, Winn RJ. Clinical management of hereditary nonpolyposis colon cancer. High-risk clinics and registries. Hematol Oncol Clin North Am. 1989 Mar; 3(1):75-86. PMID: 2917964.
      Citations:    Fields:    Translation:Humans
    243. Lynch HT, Lanspa SJ, Boman BM, Smyrk T, Watson P, Lynch JF, Lynch PM, Cristofaro G, Bufo P, Tauro AV, et al. Hereditary nonpolyposis colorectal cancer--Lynch syndromes I and II. Gastroenterol Clin North Am. 1988 Dec; 17(4):679-712. PMID: 3068137.
      Citations: 23     Fields:    Translation:Humans
    244. Lynch HT, Lynch PM, Kimberling WJ, Lynch JF. Medical genetics, Huntington's chorea, and legal questions pertaining to autopsy. Am J Med. 1983 Jul; 75(1):157-60. PMID: 6222650.
      Citations:    Fields:    Translation:Humans
    245. Lynch HT, Lynch PM, Lynch JF, Danes BS. What is hereditary colon cancer? Prog Clin Biol Res. 1983; 115:3-38. PMID: 6856637.
      Citations: 1     Fields:    Translation:Humans
    246. Lynch HT, Albano WA, Lynch JF, Lynch PM, Campbell A. Surveillance and management of patients at high genetic risk for ovarian carcinoma. Obstet Gynecol. 1982 May; 59(5):589-96. PMID: 7070730.
      Citations: 15     Fields:    Translation:Humans
    247. Lynch HT, Ruma TA, Albano WA, Lynch JF, Lynch PM. Phenotypic variation in hereditary adenomatosis: unusual tumor spectrum. Dis Colon Rectum. 1982 Apr; 25(3):235-8. PMID: 6121689.
      Citations: 2     Fields:    Translation:Humans
    248. Lynch HT, Albano WA, Recabaren JA, Fain PR, Lynch PM. Survival in hereditary breast and colon cancer. JAMA. 1981 Sep 11; 246(11):1197. PMID: 7265408.
      Citations: 2     Fields:    Translation:Humans
    249. Lynch HT, Albano W, Recerbaren J, Lynch PM, Lynch JF, Elston R. Prolonged survival as a component of a hereditary breast and nonpolyposis colon cancer. Med Hypotheses. 1981 Sep; 7(9):1201-9. PMID: 7289928.
      Citations: 7     Fields:    Translation:Humans
    250. Lynch HT, Lynch PM, Albano WA, Lynch JF. The cancer family syndrome: a status report. Dis Colon Rectum. 1981 May-Jun; 24(4):311-22. PMID: 7238243.
      Citations: 9     Fields:    Translation:Humans
    251. Lynch HT, Lynch PM, Pester J, Fusaro RM. The cancer family syndrome. Rare cutaneous phenotypic linkage of Torre's syndrome. Arch Intern Med. 1981 Apr; 141(5):607-11. PMID: 7224741.
      Citations: 37     Fields:    Translation:Humans
    252. Fusaro RM, Lynch HT, Pester J, Lynch PM. Torre's syndrome as phenotypic expression of cancer family syndrome. Arch Dermatol. 1980 Sep; 116(9):986-7. PMID: 7416766.
      Citations: 2     Fields:    Translation:Humans
    253. Lynch HT, Follett KL, Lynch PM, Albano WA, Mailliard JL, Pierson RL. Family history in an oncology clinic. Implications for cancer genetics. JAMA. 1979 Sep 21; 242(12):1268-72. PMID: 480539.
      Citations: 17     Fields:    Translation:Humans
    254. Lynch HT, Lynch PM. The cancer-family syndrome: a pragmatic basis for syndrome identification. Dis Colon Rectum. 1979 Mar; 22(2):106-10. PMID: 428275.
      Citations: 5     Fields:    Translation:Humans
    255. Lynch HT, Lynch PM, Follett KL, Harris RE. Familial polyposis coli: heterogeneous polyp expression in 2 kindreds. J Med Genet. 1979 Feb; 16(1):1-7. PMID: 38339; PMCID: PMC1012771.
      Citations: 1     Fields:    Translation:Humans
    256. Lynch HT, Guirgis HA, Harris RE, Lynch PM, Lynch JF, Elston RC, Go RC, Kaplan E. Clinical, genetic, and biostatistical progress in the cancer family syndrome. Front Gastrointest Res. 1979; 4:142-50. PMID: 428886.
      Citations:    Fields:    Translation:Humans
    257. Lynch HT, Lynch PM, Harris RE. Minimal genetic findings and their cancer control implications. A family with the cancer family syndrome. JAMA. 1978 Aug 11; 240(6):535-8. PMID: 671663.
      Citations: 2     Fields:    Translation:Humans
    258. Lynch HT, Lynch PM. Genetics and cancer in children. Pediatr Ann. 1978 Jun; 7(6):71-83, 87-8, 90 passim. PMID: 209389.
      Citations:    Fields:    Translation:HumansCells
    259. Lynch HT, Bardawil WA, Harris RE, Lynch PM, Guirgis HA, Lynch JF. Multiple primary cancers and prolonged survival: familial colonic and endometrial cancers. Dis Colon Rectum. 1978 Apr; 21(3):165-8. PMID: 274258.
      Citations: 7     Fields:    Translation:Humans
    260. Lynch PM, Lynch HT. Genetic counseling of high-cancer-risk patients: jurisprudential considerations. Semin Oncol. 1978 Mar; 5(1):107-18. PMID: 345449.
      Citations:    Fields:    Translation:Humans
    261. Lynch HT, Organ CH, Harris RE, Guirgis HA, Lynch PM, Lynch JF. Familial cancer: implications for surgical management of high-risk patients. Surgery. 1978 Jan; 83(1):104-13. PMID: 339389.
      Citations: 1     Fields:    Translation:Humans
    262. Lynch PM, Lynch HT, Harris RE. Hereditary proximal colonic cancer. Dis Colon Rectum. 1977 Nov-Dec; 20(8):661-8. PMID: 923394.
      Citations: 25     Fields:    Translation:Humans
    263. Lynch HT, Harris RE, Lynch PM, Guirgis HA, Lynch JF, Bardawil WA. Role of heredity in multiple primary cancer. Cancer. 1977 Oct; 40(4 Suppl):1849-54. PMID: 907988.
      Citations: 23     Fields:    Translation:Humans
    264. Lynch HT, Lynch PM, Harris RE. Proximal colon cancer in familial carcinoma of the colon exclusive of familial polyposis coli. Lancet. 1977 Jun 18; 1(8025):1306-7. PMID: 68400.
      Citations:    Fields:    Translation:Humans
    265. Lynch HT, Guirgis HA, Lynch PM, Lynch JF, Harris RE. Familial cancer syndromes: a survey. Cancer. 1977 Apr; 39(4 Suppl):1867-81. PMID: 404022.
      Citations: 7     Fields:    Translation:Humans
    266. Lynch HT, Harris RE, Organ CH, Guirgis HA, Lynch PM, Lynch JF, Nelson EJ. The surgeon, genetics, and cancer control: the Cancer Family Syndrome. Ann Surg. 1977 Apr; 185(4):435-40. PMID: 557313; PMCID: PMC1396131.
      Citations: 2     Fields:    Translation:HumansAnimals
    267. Lynch HT, Harris RE, Bardawil WA, Lynch PM, Guirgis HA, Swartz MJ, Lynch JF. Management of hereditary site-specific colon cancer. Arch Surg. 1977 Feb; 112(2):170-4. PMID: 836152.
      Citations: 8     Fields:    Translation:Humans
    268. Lynch HT, Terasaki PI, Guirgis HA, Sherard BD, Androsh KL, Harris RE, King MC, Petrakis N, Lynch J, Maloney K, Rankin L, Lynch PM, Elston R, Mulcahy G, Platt R. HLA in breast cancer-prone families and the cancer family syndrome. Prog Clin Biol Res. 1977; 16:149-62. PMID: 905320.
      Citations: 1     Fields:    Translation:Humans
    269. Lynch HT, Harris RE, Guirgis HA, Lynch PM, Maloney K, Rankin L, Lynch J. Early age of onset and familial breast cancer. Lancet. 1976 Sep 18; 2(7986):626-7. PMID: 61359.
      Citations: 1     Fields:    Translation:Humans
    270. Lynch HT, Brodkey FD, Lynch P, Lynch J, Maloney K, Rankin L, Kraft C, Swartz M, Westercamp T, Guirgis HA. Familial risk and cancer control. JAMA. 1976 Aug 09; 236(6):582-4. PMID: 947240.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    271. Lynch PM, Lynch HT. Medical-legal aspects of familial cancer. J Leg Med (N Y). 1976 May; 4(5):10-6. PMID: 1084385.
      Citations:    Fields:    
    272. Lynch HT, Guirgis H, Brodkey F, Maloney K, Lynch PM, Rankin L, Lynch J. Early age of onset in familial breast cancer. Genetic and cancer control implications. Arch Surg. 1976 Feb; 111(2):126-31. PMID: 1252118.
      Citations: 11     Fields:    Translation:Humans
    273. Lynch HT, Mulcahy GM, Lynch P, Guirgis H, Brodkey F, Lynch J, Maloney K, Rankin L. Genetic factors in breast cancer: a survey. Pathol Annu. 1976; 11:77-101. PMID: 794807.
      Citations: 1     Fields:    Translation:Humans
    274. Lynch HT, Brodkey FD, Guirgis HA, Swartz MJ, Lynch JF, Lynch PM. Survival data from a multiphasic mobile cancer detection unit. Oncology. 1976; 33(4):179-82. PMID: 1018882.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    275. Foley GE, Handler AH, Lynch PM, Wolman SR, Stulberg CS, Eagle H. Loss of neoplastic properties in vitro. II. Observations on KB sublines. Cancer Res. 1965 Sep; 25(8):1254-61. PMID: 5839717.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    276. Genetic/familial high-risk assessment. JNCCN Journal of the National Comprehensive Cancer Network. 14:1010-1030.
    277. Palliation of malignant gastric outlet and duodenal obstruction using expandable metallic stents. Gastrointestinal Endoscopy. 47.
    278. Response. Journal of the National Cancer Institute. 83:1688-1689.
    279. Host factors in cancer prevention. Cancer Detection and Prevention. 2:47-64.
    280. Molecular genetics of familial colorectal cancer. Cancer Bulletin. 46:315-321.
    281. Surveillance in hereditary nonpolyposis colorectal cancer. Diseases of the Colon and Rectum. 36:425-429.
    282. Medical/legal issues in genetic testing. Cancer. 80:630-631.
    283. National activities. Anticancer Research. 14:1665-1673.
    284. Hnpcc. Giornale Italiano di Endoscopia Digestiva. 38:271-273.
    285. Endoscopic management of biliary tract cancer with the wallstent. Gastrointestinal Endoscopy. 45.
    286. Comparison between metastatic vs primary biliary tract cancer in their response to the wallstent. Gastrointestinal Endoscopy. 45.
    287. Discussion. Clinical Cancer Research. 13.
    288. Cancer screening guidelines and prevention factors for high-risk patients with a family history of colorectal cancer. Current Colorectal Cancer Reports. 1:110-116.
    289. Cancer screening behaviors and risk perceptions among family members of colorectal cancer patients with unexplained mismatch repair deficiency. Familial Cancer. 1-7.
    290. Familial Cancer. 1-5.
    291. Screening adherence and cancer risk perceptions in colorectal cancer survivors with Lynch-like syndrome. Clinical Genetics. 89:392-398.
    292. Outcome of EMR as an alternative to surgery in patients with complex colon polyps. Gastrointestinal Endoscopy.
    293. Palliation of malignant colorectal strictures with expandable metallic stents. Gastrointestinal Endoscopy. 47.
    294. Familial Clustering of Plasma Carcinoembryonic Antigen (CEA) in the Cancer Family Syndrome. Scandinavian Journal of Immunology. 8:465-470.
    295. Palliation of malignant dysphagia and fistulae with the Wwallstent. Gastrointestinal Endoscopy. 45.
    296. Colon cancer. 77-84.
    297. A proposed staging system and stage-specific interventions for familial adenomatous polyposis. Gastrointestinal Endoscopy.
    298. DNA Mismatch Repair Deficiency in Rectal Cancer. Journal of Clinical Oncology. 34:3039-3046.
    299. Distress in the cancer patient and its association with genetic testing and counseling for hereditary non-polyposis colon cancer. Cancer Research Therapy and Control. 8:35-49.
    300. Mutation Spectrum and Risk of Colorectal Cancer in African American Families with Lynch Syndrome. Gastroenterology. 149:1446-1453.
    301. High prevalence of hereditary cancer syndromes in adolescents and young adults with colorectal cancer. Journal of Clinical Oncology. 33:3544-3549.
    302. FIFTH INTERNATIONAL CONGRESS OF HUMAN GENETICS.
    303. Family History in an Oncology Clinic. JAMA - Journal of the American Medical Association. 242:1268-1272.
    304. Palliation of malignant dysphagia with chemoradiation therapy (ChXRT) does not increase the rate of serious complications with coated Wallstent. Gastrointestinal Endoscopy. 45.
    305. PMS2 monoallelic mutation carriers. Genetics in Medicine. 18:13-19.
    306. Comparison of nonampullary duodenal adenomas in patients with familial adenomatous polyposis versus patients with sporadic adenomas. Gastrointestinal Endoscopy.
    307. Benefits and Risks of Screening Mammography in Women With BRCA1 and BRCA2 Mutations-Reply. JAMA - Journal of the American Medical Association. 278:290.
    308. FIFTH INTERNATIONAL CONGRESS OF HUMAN GENETICS.
    309. The role of aspirin in the Prevention of polyp recurrence. Current Colorectal Cancer Reports. 3:24-28.
    310. Management of malignant colorectal strictures with expandable endoprosthesis. Gastrointestinal Endoscopy. 45.
    311. Tumor factors that may affect the outcome after palliation with the esophageal Wallstent?. Gastrointestinal Endoscopy. 45.
    312. The role of genetics and host factors in cancer susceptibility and cancer resistance. Cancer Detection and Prevention. 1:175-224.
    313. Medicolegal Aspects of Endoscopic Screening and Genetic Testing in Hereditary Colon Cancer Syndromes. Techniques in Gastrointestinal Endoscopy. 8:133-139.
    314. Patient-reported disease knowledge and educational needs in Lynch syndrome. Hereditary Cancer in Clinical Practice. 12.
    315. Historical development of Lynch syndrome. 1-24.
    316. Clinical challenges in management of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer. Cancer. 86:1713-1719.
    317. Identification of a novel PMS2 alteration c.505C>G (R169G) in trans with a PMS2 pathogenic mutation in a patient with constitutional mismatch repair deficiency. Familial Cancer. 1-5.
    318. Management of digestive-respiratory fistulae (DRF) with coated expandable esophageal stents (cEES). Gastrointestinal Endoscopy. 43:343.
    319. The overall complication rate after esophageal Wallstent is related to the esophageal location of the lesion. Gastrointestinal Endoscopy. 45.
    320. Computed tomographic colonography. Evidence-Based Gastroenterology. 5:84-85.
    321. Screening guidelines for colorectal cancer. Cancer Bulletin. 46:359-364.
    322. Management of a rectovesical malignant fistula with the coated wallstent. Gastrointestinal Endoscopy. 45.
    323. Discussion. Clinical Cancer Research. 13.
    324. Chemoprevention of familial adenomatous polyposis. Familial Cancer. 1-9.
    325. Colorectal cancer screening. JNCCN Journal of the National Comprehensive Cancer Network. 8:8-60.
    326. Does chemo-radiation therapy (ChXRT) increase the incidence of complications after self-expanding coated stents (cEES) in the management of malignant esophageal strictures?. Gastrointestinal Endoscopy. 43:343.
    327. Genomic landscape of colorectal mucosa and adenomas. Cancer Prevention Research. 9:417-427.
    328. Does the response to plastic stent(PS) predict that of wallstent(WS) in the treatment of malignant biliary obstruction(MBO)?. Gastrointestinal Endoscopy. 47.
    329. Chemoprevention of hereditary colon cancers. Nature Reviews Gastroenterology and Hepatology. 13:352-361.
    330. How much luminal dilation (if any) is necessary prior to placement of an esophageal Wallstent?. Gastrointestinal Endoscopy. 45.
    331. Natural language processing as an alternative to manual reporting of colonoscopy quality metrics. Gastrointestinal Endoscopy.
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