InstitutionMD Anderson
DepartmentGenitourinary Medical Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Matsuo K, Nishimura M, Bottsford-Miller JN, Huang J, Komurov K, Armaiz-Pena GN, Shahzad MMK, Stone RL, Roh JW, Sanguino AM, Lu C, Im DD, Rosenshien NB, Sakakibara A, Nagano T, Yamasaki M, Enomoto T, Kimura T, Ram PT, Schmeler KM, Gallick GE, Wong KK, Frumovitz M, Sood AK. Editor's Note: Targeting Src in Mucinous Ovarian Carcinoma. Clin Cancer Res. 2021 08 01; 27(15):4450. PMID: 34341055.
      Citations:    Fields:    
    2. Kim HS, Han HD, Armaiz-Pena GN, Stone RL, Nam EJ, Lee JW, Shahzad MMK, Nick AM, Lee SJ, Roh JW, Nishimura M, Mangala LS, Bottsford-Miller J, Gallick GE, Lopez-Berestein G, Sood AK. Editor's Note: Functional Roles of Src and Fgr in Ovarian Carcinoma. Clin Cancer Res. 2021 08 01; 27(15):4452. PMID: 34341057.
      Citations:    Fields:    
    3. Yu G, Shen P, Lee YC, Pan J, Song JH, Pan T, Lin SC, Liang X, Wang G, Panaretakis T, Logothetis CJ, Gallick GE, Yu-Lee LY, Lin SH. Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4. iScience. 2021 Apr 23; 24(4):102388. PMID: 33981975; PMCID: PMC8086028.
      Citations: 1     
    4. Vardaki I, Corn P, Gentile E, Song JH, Madan N, Hoang A, Parikh N, Guerra L, Lee YC, Lin SC, Yu G, Santos E, Melancon MP, Troncoso P, Navone N, Gallick GE, Efstathiou E, Subudhi SK, Lin SH, Logothetis CJ, Panaretakis T. Radium-223 Treatment Increases Immune Checkpoint Expression in Extracellular Vesicles from the Metastatic Prostate Cancer Bone Microenvironment. Clin Cancer Res. 2021 06 01; 27(11):3253-3264. PMID: 33753455; PMCID: PMC8172463.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    5. Gray MJ, Dallas NA, Van Buren G, Xia L, Yang AD, Somcio RJ, Gaur P, Mangala LS, Vivas-Mejia PE, Fan F, Sanguino AM, Gallick GE, Lopez-Berestein G, Sood AK, Ellis LM. Correction: Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver. Oncogene. 2020 Jun; 39(23):4619. PMID: 32366906.
      Citations:    Fields:    
    6. Pan T, Martinez M, Hubka KM, Song JH, Lin SC, Yu G, Lee YC, Gallick GE, Tu SM, Harrington DA, Farach-Carson MC, Lin SH, Satcher RL. Cabozantinib Reverses Renal Cell Carcinoma-mediated Osteoblast Inhibition in Three-dimensional Coculture In Vitro and Reduces Bone Osteolysis In Vivo. Mol Cancer Ther. 2020 06; 19(6):1266-1278. PMID: 32220969; PMCID: PMC7272308.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    7. Koinis F, Corn P, Parikh N, Song J, Vardaki I, Mourkioti I, Lin SH, Logothetis C, Panaretakis T, Gallick G. Resistance to MET/VEGFR2 Inhibition by Cabozantinib Is Mediated by YAP/TBX5-Dependent Induction of FGFR1 in Castration-Resistant Prostate Cancer. Cancers (Basel). 2020 Jan 19; 12(1). PMID: 31963871; PMCID: PMC7016532.
      Citations: 6     
    8. Corn PG, Zhang M, Nogueras-Gonzalez GM, Xiao L, Zurita AJ, Subudhi SK, Tu SM, Aparicio AM, Coarfa C, Rajapakshe K, Huang S, Navone NM, Lin SH, Wang G, Ramachandran S, Titus MA, Panaretakis T, Gallick GE, Efstathiou E, Troncoso P, Logothetis C. A Phase II Study of Cabozantinib and Androgen Ablation in Patients with Hormone-Na?ve Metastatic Prostate Cancer. Clin Cancer Res. 2020 03 01; 26(5):990-999. PMID: 31941830.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    9. Karuturi MS, Holmes HM, Lei X, Johnson M, Barcenas CH, Cantor SB, Gallick GE, Bast RC, Giordano SH. Potentially inappropriate medications defined by STOPP criteria in older patients with breast and colorectal cancer. J Geriatr Oncol. 2019 09; 10(5):705-708. PMID: 30795923; PMCID: PMC6699920.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    10. Karuturi MS, Holmes HM, Lei X, Johnson M, Barcenas CH, Cantor SB, Gallick GE, Bast RC, Giordano SH. Potentially inappropriate medication use in older patients with breast and colorectal cancer. Cancer. 2018 07 15; 124(14):3000-3007. PMID: 29689595; PMCID: PMC6033638.
      Citations: 15     Fields:    Translation:Humans
    11. Yu G, Cheng CJ, Lin SC, Lee YC, Frigo DE, Yu-Lee LY, Gallick GE, Titus MA, Nutt LK, Lin SH. Organelle-Derived Acetyl-CoA Promotes Prostate Cancer Cell Survival, Migration, and Metastasis via Activation of Calmodulin Kinase II. Cancer Res. 2018 05 15; 78(10):2490-2502. PMID: 29535221; PMCID: PMC6556391.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    12. Yu-Lee LY, Yu G, Lee YC, Lin SC, Pan J, Pan T, Yu KJ, Liu B, Creighton CJ, Rodriguez-Canales J, Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE, Lin SH. Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGF?RIII-p38MAPK-pS249/T252RB Pathway. Cancer Res. 2018 06 01; 78(11):2911-2924. PMID: 29514796; PMCID: PMC5984689.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    13. Pan T, Lin SC, Yu KJ, Yu G, Song JH, Lewis VO, Bird JE, Moon B, Lin PP, Tannir NM, Jonasch E, Wood CG, Gallick GE, Yu-Lee LY, Lin SH, Satcher RL. BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation. Neoplasia. 2018 01; 20(1):32-43. PMID: 29190493; PMCID: PMC5711998.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    14. Wang S, Liang K, Hu Q, Li P, Song J, Yang Y, Yao J, Mangala LS, Li C, Yang W, Park PK, Hawke DH, Zhou J, Zhou Y, Xia W, Hung MC, Marks JR, Gallick GE, Lopez-Berestein G, Flores ER, Sood AK, Huang S, Yu D, Yang L, Lin C. JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. J Clin Invest. 2017 12 01; 127(12):4498-4515. PMID: 29130936; PMCID: PMC5707156.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    15. Yu KJ, Li JK, Lee YC, Yu G, Lin SC, Pan T, Satcher RL, Titus MA, Yu-Lee LY, Weng WH, Gallick GE, Lin SH. Cabozantinib-induced osteoblast secretome promotes survival and migration of metastatic prostate cancer cells in bone. Oncotarget. 2017 Sep 26; 8(43):74987-75006. PMID: 29088840; PMCID: PMC5650395.
      Citations: 7     Fields:    
    16. Bilen MA, Pan T, Lee YC, Lin SC, Yu G, Pan J, Hawke D, Pan BF, Vykoukal J, Gray K, Satcher RL, Gallick GE, Yu-Lee LY, Lin SH. Proteomics Profiling of Exosomes from Primary Mouse Osteoblasts under Proliferation versus Mineralization Conditions and Characterization of Their Uptake into Prostate Cancer Cells. J Proteome Res. 2017 08 04; 16(8):2709-2728. PMID: 28675788; PMCID: PMC5860883.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    17. Lin SC, Lee YC, Yu G, Cheng CJ, Zhou X, Chu K, Murshed M, Le NT, Baseler L, Abe JI, Fujiwara K, deCrombrugghe B, Logothetis CJ, Gallick GE, Yu-Lee LY, Maity SN, Lin SH. Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer. Dev Cell. 2017 06 05; 41(5):467-480.e3. PMID: 28586644; PMCID: PMC5512590.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    18. Li L, Karanika S, Yang G, Wang J, Park S, Broom BM, Manyam GC, Wu W, Luo Y, Basourakos S, Song JH, Gallick GE, Karantanos T, Korentzelos D, Azad AK, Kim J, Corn PG, Aparicio AM, Logothetis CJ, Troncoso P, Heffernan T, Toniatti C, Lee HS, Lee JS, Zuo X, Chang W, Yin J, Thompson TC. Androgen receptor inhibitor-induced "BRCAness" and PARP inhibition are synthetically lethal for castration-resistant prostate cancer. Sci Signal. 2017 May 23; 10(480). PMID: 28536297; PMCID: PMC5855082.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    19. Parseghian CM, Parikh NU, Wu JY, Jiang ZQ, Henderson L, Tian F, Raghav K, Dasari A, Fogelman DR, Katsiampoura AD, Menter DG, Wolff RA, Eng C, Overman MJ, Gallick GE, Kopetz S, Pastor B, Ychou M, Thierry AR. Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer. Clin Cancer Res. 2017 Aug 01; 23(15):4146-4154. PMID: 28280091; PMCID: PMC5540760.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    20. Karanika S, Karantanos T, Li L, Wang J, Park S, Yang G, Zuo X, Song JH, Maity SN, Manyam GC, Broom B, Aparicio AM, Gallick GE, Troncoso P, Corn PG, Navone N, Zhang W, Li S, Thompson TC. Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling. Cell Rep. 2017 02 21; 18(8):1970-1981. PMID: 28228262; PMCID: PMC5349188.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    21. Li C, Wang S, Xing Z, Lin A, Liang K, Song J, Hu Q, Yao J, Chen Z, Park PK, Hawke DH, Zhou J, Zhou Y, Zhang S, Liang H, Hung MC, Gallick GE, Han L, Lin C, Yang L. A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis. Nat Cell Biol. 2017 02; 19(2):106-119. PMID: 28114269; PMCID: PMC5336186.
      Citations: 131     Fields:    Translation:HumansCells
    22. Dayyani F, Zurita AJ, Slack R, Millikan RE, Araujo JC, Gallick GE, Logothetis CJ, Corn PG, Nogueras-Gonz?lez GM. The combination of serum insulin, osteopontin, and hepatocyte growth factor predicts time to castration-resistant progression in androgen dependent metastatic prostate cancer- an exploratory study. BMC Cancer. 2016 09 06; 16:721. PMID: 27599544; PMCID: PMC5013640.
      Citations: 6     Fields:    Translation:Humans
    23. Sun S, Zhou X, Corvera J, Gallick GE, Lin SH, Kuang J. Erratum: ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction. Cell Discov. 2016; 2:16023. PMID: 27462994; PMCID: PMC4915270.
    24. Lee YC, Lin SC, Yu G, Cheng CJ, Liu B, Liu HC, Hawke DH, Parikh NU, Varkaris A, Corn P, Logothetis C, Satcher RL, Yu-Lee LY, Gallick GE, Lin SH. Identification of Bone-Derived Factors Conferring De Novo Therapeutic Resistance in Metastatic Prostate Cancer. Cancer Res. 2015 Nov 15; 75(22):4949-59. PMID: 26530902; PMCID: PMC4651787.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    25. Gaur S, Wen Y, Song JH, Parikh NU, Mangala LS, Blessing AM, Ivan C, Wu SY, Varkaris A, Shi Y, Lopez-Berestein G, Frigo DE, Sood AK, Gallick GE. Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy. Oncotarget. 2015 Oct 06; 6(30):29161-77. PMID: 26313360; PMCID: PMC4745718.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    26. Hahn NM, Knudsen BS, Daneshmand S, Koch MO, Bihrle R, Foster RS, Gardner TA, Cheng L, Liu Z, Breen T, Fleming MT, Lance R, Corless CL, Alva AS, Shen SS, Huang F, Gertych A, Gallick GE, Mallick J, Ryan C, Galsky MD, Lerner SP, Posadas EM, Sonpavde G. Neoadjuvant dasatinib for muscle-invasive bladder cancer with tissue analysis of biologic activity. Urol Oncol. 2016 Jan; 34(1):4.e11-7. PMID: 26362343.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    27. Varkaris A, Corn PG, Parikh NU, Efstathiou E, Song JH, Lee YC, Aparicio A, Hoang AG, Gaur S, Thorpe L, Maity SN, Bar Eli M, Czerniak BA, Shao Y, Alauddin M, Lin SH, Logothetis CJ, Gallick GE. Integrating Murine and Clinical Trials with Cabozantinib to Understand Roles of MET and VEGFR2 as Targets for Growth Inhibition of Prostate Cancer. Clin Cancer Res. 2016 Jan 01; 22(1):107-21. PMID: 26272062; PMCID: PMC4703437.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    28. Sun S, Zhou X, Corvera J, Gallick GE, Lin SH, Kuang J. ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction. Cell Discov. 2015; 1:15018. PMID: 27462417; PMCID: PMC4860835.
      Citations: 14     
    29. Reddy SM, Kopetz S, Morris J, Parikh N, Qiao W, Overman MJ, Fogelman D, Shureiqi I, Jacobs C, Malik Z, Jimenez CA, Wolff RA, Abbruzzese JL, Gallick G, Eng C. Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer. Invest New Drugs. 2015 Aug; 33(4):977-84. PMID: 26062928.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    30. Chatterji T, Varkaris AS, Parikh NU, Song JH, Cheng CJ, Schweppe RE, Alexander S, Davis JW, Troncoso P, Friedl P, Kuang J, Lin SH, Gallick GE. Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells. Oncotarget. 2015 Apr 30; 6(12):10175-94. PMID: 25868388; PMCID: PMC4496348.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    31. Sun S, Zhou X, Kuang J, Zhang W, Gallick GE. Unravelling the pivotal role of Alix in MVB sorting and silencing of the activated EGFR. Biochem J. 2015 Mar 15; 466(3):475-87. PMID: 25510652; PMCID: PMC4495973.
      Citations: 21     Fields:    Translation:HumansCells
    32. Vishwamitra D, Curry CV, Alkan S, Song YH, Gallick GE, Kaseb AO, Shi P, Amin HM. The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK? T-cell lymphoma. Mol Cancer. 2015 Feb 25; 14:53. PMID: 25884514; PMCID: PMC4415347.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    33. Gajdosik MS, Josic D, Lee YC, Clifton JG, Logothetis C, Yu-Lee LY, Gallick GE, Maity SN, Lin SH. Secretome analysis of an osteogenic prostate tumor identifies complex signaling networks mediating cross-talk of cancer and stromal cells within the tumor microenvironment. Mol Cell Proteomics. 2015 Mar; 14(3):471-83. PMID: 25527621; PMCID: PMC4349970.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    34. Kopetz S, Morris VK, Parikh N, Overman MJ, Jiang ZQ, Maru D, Elvin P, Gallick G. Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer. BMC Cancer. 2014 Sep 10; 14:660. PMID: 25208577; PMCID: PMC4167273.
      Citations: 8     Fields:    Translation:Humans
    35. Yu G, Lee YC, Cheng CJ, Wu CF, Song JH, Gallick GE, Yu-Lee LY, Kuang J, Lin SH. RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival. Mol Cancer Res. 2015 Feb; 13(2):348-57. PMID: 25189355; PMCID: PMC4336832.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    36. Varkaris A, Katsiampoura AD, Araujo JC, Gallick GE, Corn PG. Src signaling pathways in prostate cancer. Cancer Metastasis Rev. 2014 Sep; 33(2-3):595-606. PMID: 24522479; PMCID: PMC4640186.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    37. Jin JK, Tien PC, Cheng CJ, Song JH, Huang C, Lin SH, Gallick GE. Talin1 phosphorylation activates ?1 integrins: a novel mechanism to promote prostate cancer bone metastasis. Oncogene. 2015 Apr 02; 34(14):1811-21. PMID: 24793790; PMCID: PMC4221586.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    38. Satcher RL, Pan T, Cheng CJ, Lee YC, Lin SC, Yu G, Li X, Hoang AG, Tamboli P, Jonasch E, Gallick GE, Lin SH. Cadherin-11 in renal cell carcinoma bone metastasis. PLoS One. 2014; 9(2):e89880. PMID: 24587095; PMCID: PMC3933681.
      Citations: 19     Fields:    Translation:AnimalsCells
    39. Liu T, Hu W, Dalton HJ, Choi HJ, Huang J, Kang Y, Pradeep S, Miyake T, Song JH, Wen Y, Lu C, Pecot CV, Bottsford-Miller J, Zand B, Jennings NB, Ivan C, Gallick GE, Baggerly KA, Hangauer DG, Coleman RL, Frumovitz M, Sood AK. Targeting SRC and tubulin in mucinous ovarian carcinoma. Clin Cancer Res. 2013 Dec 01; 19(23):6532-43. PMID: 24100628; PMCID: PMC3852199.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    40. Bartley AN, Parikh N, Hsu CH, Roe DJ, Buckmeier JA, Corley L, Phipps RA, Gallick G, Lance P, Thompson PA, Hamilton SR. Colorectal adenoma stem-like cell populations: associations with adenoma characteristics and metachronous colorectal neoplasia. Cancer Prev Res (Phila). 2013 Nov; 6(11):1162-70. PMID: 24008128; PMCID: PMC4079278.
      Citations: 7     Fields:    Translation:HumansCells
    41. Lee YC, Bilen MA, Yu G, Lin SC, Huang CF, Ortiz A, Cho H, Song JH, Satcher RL, Kuang J, Gallick GE, Yu-Lee LY, Huang W, Lin SH. Inhibition of cell adhesion by a cadherin-11 antibody thwarts bone metastasis. Mol Cancer Res. 2013 Nov; 11(11):1401-11. PMID: 23913163; PMCID: PMC3834228.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    42. Logothetis CJ, Gallick GE, Maity SN, Kim J, Aparicio A, Efstathiou E, Lin SH. Molecular classification of prostate cancer progression: foundation for marker-driven treatment of prostate cancer. Cancer Discov. 2013 Aug; 3(8):849-61. PMID: 23811619; PMCID: PMC3926428.
      Citations: 66     Fields:    Translation:Humans
    43. Henderson YC, Toro-Serra R, Chen Y, Ryu J, Frederick MJ, Zhou G, Gallick GE, Lai SY, Clayman GL. Src inhibitors in suppression of papillary thyroid carcinoma growth. Head Neck. 2014 Mar; 36(3):375-84. PMID: 23729178; PMCID: PMC4401074.
      Citations: 11     Fields:    Translation:AnimalsCells
    44. Wu CF, Liu S, Lee YC, Wang R, Sun S, Yin F, Bornmann WG, Yu-Lee LY, Gallick GE, Zhang W, Lin SH, Kuang J. RSK promotes G2/M transition through activating phosphorylation of Cdc25A and Cdc25B. Oncogene. 2014 May 01; 33(18):2385-94. PMID: 23708659; PMCID: PMC4026278.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    45. Varkaris A, Gaur S, Parikh NU, Song JH, Dayyani F, Jin JK, Logothetis CJ, Gallick GE. Ligand-independent activation of MET through IGF-1/IGF-1R signaling. Int J Cancer. 2013 Oct 01; 133(7):1536-46. PMID: 23526299; PMCID: PMC3713179.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    46. Dayyani F, Varkaris A, Araujo JC, Song JH, Chatterji T, Trudel GC, Logothetis CJ, Gallick GE. Increased serum insulin-like growth factor-1 levels are associated with prolonged response to dasatinib-based regimens in metastatic prostate cancer. Prostate. 2013 Jun; 73(9):979-85. PMID: 23371521; PMCID: PMC4013833.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    47. Lee YC, Jin JK, Cheng CJ, Huang CF, Song JH, Huang M, Brown WS, Zhang S, Yu-Lee LY, Yeh ET, McIntyre BW, Logothetis CJ, Gallick GE, Lin SH. Targeting constitutively activated ?1 integrins inhibits prostate cancer metastasis. Mol Cancer Res. 2013 Apr; 11(4):405-17. PMID: 23339185; PMCID: PMC3631285.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    48. Armaiz-Pena GN, Allen JK, Cruz A, Stone RL, Nick AM, Lin YG, Han LY, Mangala LS, Villares GJ, Vivas-Mejia P, Rodriguez-Aguayo C, Nagaraja AS, Gharpure KM, Wu Z, English RD, Soman KV, Shahzad MM, Shazhad MM, Zigler M, Deavers MT, Zien A, Soldatos TG, Jackson DB, Wiktorowicz JE, Torres-Lugo M, Young T, De Geest K, Gallick GE, Bar-Eli M, Lopez-Berestein G, Cole SW, Lopez GE, Lutgendorf SK, Sood AK. Src activation by ?-adrenoreceptors is a key switch for tumour metastasis. Nat Commun. 2013; 4:1403. PMID: 23360994; PMCID: PMC3561638.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    49. Dayyani F, Parikh NU, Varkaris AS, Song JH, Moorthy S, Chatterji T, Maity SN, Wolfe AR, Carboni JM, Gottardis MM, Logothetis CJ, Gallick GE. Combined Inhibition of IGF-1R/IR and Src family kinases enhances antitumor effects in prostate cancer by decreasing activated survival pathways. PLoS One. 2012; 7(12):e51189. PMID: 23300537; PMCID: PMC3530555.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    50. Mao M, Tian F, Mariadason JM, Tsao CC, Lemos R, Dayyani F, Gopal YN, Jiang ZQ, Wistuba II, Tang XM, Bornman WG, Bollag G, Mills GB, Powis G, Desai J, Gallick GE, Davies MA, Kopetz S. Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents. Clin Cancer Res. 2013 Feb 01; 19(3):657-67. PMID: 23251002; PMCID: PMC3563727.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    51. Hong DS, Choe JH, Naing A, Wheler JJ, Falchook GS, Piha-Paul S, Moulder SL, George GC, Choe JM, Strauss LC, Gallick GE, Kurzrock R. A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors. Invest New Drugs. 2013 Aug; 31(4):918-26. PMID: 23179336; PMCID: PMC4482128.
      Citations: 18     Fields:    Translation:HumansCellsCTClinical Trials
    52. Kim KB, Prieto V, Joseph RW, Diwan AH, Gallick GE, Papadopoulos NE, Bedikian AY, Camacho LH, Hwu P, Ng CS, Wei W, Johnson MM, Wittemer SM, Vardeleon A, Reckeweg A, Colevas AD. A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma. Melanoma Res. 2012 Aug; 22(4):294-301. PMID: 22668797; PMCID: PMC3880198.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    53. Gallick GE, Corn PG, Zurita AJ, Lin SH. Small-molecule protein tyrosine kinase inhibitors for the treatment of metastatic prostate cancer. Future Med Chem. 2012 Jan; 4(1):107-19. PMID: 22168167; PMCID: PMC3285098.
      Citations: 17     Fields:    Translation:Humans
    54. Varkaris A, Corn PG, Gaur S, Dayyani F, Logothetis CJ, Gallick GE. The role of HGF/c-Met signaling in prostate cancer progression and c-Met inhibitors in clinical trials. Expert Opin Investig Drugs. 2011 Dec; 20(12):1677-84. PMID: 22035268; PMCID: PMC4020016.
      Citations: 41     Fields:    Translation:Humans
    55. Dayyani F, Gallick GE, Logothetis CJ, Corn PG. Novel therapies for metastatic castrate-resistant prostate cancer. J Natl Cancer Inst. 2011 Nov 16; 103(22):1665-75. PMID: 21917607; PMCID: PMC4176261.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    56. Araujo JC, Mathew P, Armstrong AJ, Braud EL, Posadas E, Lonberg M, Gallick GE, Paliwal P, Agrawal S, Logothetis CJ, Trudel GC. Dasatinib combined with docetaxel for castration-resistant prostate cancer: results from a phase 1-2 study. Cancer. 2012 Jan 01; 118(1):63-71. PMID: 21976132; PMCID: PMC3898168.
      Citations: 69     Fields:    Translation:HumansCTClinical Trials
    57. Matsuo K, Nishimura M, Bottsford-Miller JN, Huang J, Komurov K, Armaiz-Pena GN, Shahzad MM, Stone RL, Roh JW, Sanguino AM, Lu C, Im DD, Rosenshien NB, Sakakibara A, Nagano T, Yamasaki M, Enomoto T, Kimura T, Ram PT, Schmeler KM, Gallick GE, Wong KK, Frumovitz M, Sood AK. Targeting SRC in mucinous ovarian carcinoma. Clin Cancer Res. 2011 Aug 15; 17(16):5367-78. PMID: 21737505; PMCID: PMC4028171.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    58. Kim MP, Truty MJ, Choi W, Kang Y, Chopin-Lally X, Gallick GE, Wang H, McConkey DJ, Hwang R, Logsdon C, Abbruzzesse J, Fleming JB. Molecular profiling of direct xenograft tumors established from human pancreatic adenocarcinoma after neoadjuvant therapy. Ann Surg Oncol. 2012 Jul; 19 Suppl 3:S395-403. PMID: 21701930; PMCID: PMC4112459.
      Citations: 24     Fields:    Translation:HumansAnimals
    59. Kim MP, Fleming JB, Wang H, Abbruzzese JL, Choi W, Kopetz S, McConkey DJ, Evans DB, Gallick GE. ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma. PLoS One. 2011; 6(6):e20636. PMID: 21695188; PMCID: PMC3113804.
      Citations: 160     Fields:    Translation:HumansAnimalsCells
    60. Lee YC, Cheng CJ, Bilen MA, Lu JF, Satcher RL, Yu-Lee LY, Gallick GE, Maity SN, Lin SH. BMP4 promotes prostate tumor growth in bone through osteogenesis. Cancer Res. 2011 Aug 01; 71(15):5194-203. PMID: 21670081; PMCID: PMC3148283.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    61. Jin JK, Dayyani F, Gallick GE. Steps in prostate cancer progression that lead to bone metastasis. Int J Cancer. 2011 Jun 01; 128(11):2545-61. PMID: 21365645; PMCID: PMC3082284.
      Citations: 78     Fields:    Translation:HumansAnimals
    62. Kim HS, Han HD, Armaiz-Pena GN, Stone RL, Nam EJ, Lee JW, Shahzad MM, Nick AM, Lee SJ, Roh JW, Nishimura M, Mangala LS, Bottsford-Miller J, Gallick GE, Lopez-Berestein G, Sood AK. Functional roles of Src and Fgr in ovarian carcinoma. Clin Cancer Res. 2011 Apr 01; 17(7):1713-21. PMID: 21300758; PMCID: PMC3077122.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    63. Zhou X, Si J, Corvera J, Gallick GE, Kuang J. Decoding the intrinsic mechanism that prohibits ALIX interaction with ESCRT and viral proteins. Biochem J. 2010 Dec 15; 432(3):525-34. PMID: 20929444; PMCID: PMC4391464.
      Citations: 22     Fields:    Translation:HumansCells
    64. Liu JL, Mao Z, Gallick GE, Yung WK. AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor. Neuro Oncol. 2011 Feb; 13(2):184-94. PMID: 21123367; PMCID: PMC3064623.
      Citations: 5     Fields:    Translation:HumansCells
    65. Park SI, Kim SJ, McCauley LK, Gallick GE. Pre-clinical mouse models of human prostate cancer and their utility in drug discovery. Curr Protoc Pharmacol. 2010 Dec; Chapter 14:Unit 14.15. PMID: 21483646; PMCID: PMC3072580.
      Citations: 47     Fields:    Translation:HumansAnimals
    66. Connelly SF, Isley BA, Baker CH, Gallick GE, Summy JM. Loss of tyrosine phosphatase-dependent inhibition promotes activation of tyrosine kinase c-Src in detached pancreatic cells. Mol Carcinog. 2010 Dec; 49(12):1007-21. PMID: 20945416; PMCID: PMC2991619.
      Citations: 5     Fields:    Translation:HumansCells
    67. Wang R, Jung SY, Wu CF, Qin J, Kobayashi R, Gallick GE, Kuang J. Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19885-90. PMID: 21041626; PMCID: PMC2993414.
      Citations: 7     Fields:    Translation:AnimalsCells
    68. Lee YC, Huang CF, Murshed M, Chu K, Araujo JC, Ye X, deCrombrugghe B, Yu-Lee LY, Gallick GE, Lin SH. Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts. Oncogene. 2010 Jun 03; 29(22):3196-207. PMID: 20228840; PMCID: PMC2921959.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    69. Kim MP, Evans DB, Wang H, Abbruzzese JL, Fleming JB, Gallick GE. Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice. Nat Protoc. 2009; 4(11):1670-80. PMID: 19876027; PMCID: PMC4203372.
      Citations: 206     Fields:    Translation:HumansAnimalsCells
    70. Gorlov IP, Gallick GE, Gorlova OY, Amos C, Logothetis CJ. GWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example. PLoS One. 2009 Aug 04; 4(8):e6511. PMID: 19652704; PMCID: PMC2714961.
      Citations: 25     Fields:    Translation:Humans
    71. Arumugam T, Ramachandran V, Fournier KF, Wang H, Marquis L, Abbruzzese JL, Gallick GE, Logsdon CD, McConkey DJ, Choi W. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Res. 2009 Jul 15; 69(14):5820-8. PMID: 19584296; PMCID: PMC4378690.
      Citations: 423     Fields:    Translation:HumansCells
    72. Kopetz S, Lesslie DP, Dallas NA, Park SI, Johnson M, Parikh NU, Kim MP, Abbruzzese JL, Ellis LM, Chandra J, Gallick GE. Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress. Cancer Res. 2009 May 01; 69(9):3842-9. PMID: 19383922; PMCID: PMC2709758.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    73. Wang Z, Li Y, Kong D, Banerjee S, Ahmad A, Azmi AS, Ali S, Abbruzzese JL, Gallick GE, Sarkar FH. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res. 2009 Mar 15; 69(6):2400-7. PMID: 19276344; PMCID: PMC2657919.
      Citations: 286     Fields:    Translation:HumansCells
    74. Sen B, Saigal B, Parikh N, Gallick G, Johnson FM. Sustained Src inhibition results in signal transducer and activator of transcription 3 (STAT3) activation and cancer cell survival via altered Janus-activated kinase-STAT3 binding. Cancer Res. 2009 Mar 01; 69(5):1958-65. PMID: 19223541; PMCID: PMC2929826.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    75. Kim MP, Park SI, Kopetz S, Gallick GE. Src family kinases as mediators of endothelial permeability: effects on inflammation and metastasis. Cell Tissue Res. 2009 Jan; 335(1):249-59. PMID: 18815812; PMCID: PMC3907084.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    76. Gray MJ, Dallas NA, Van Buren G, Xia L, Yang AD, Somcio RJ, Gaur P, Mangala LS, Vivas-Mejia PE, Fan F, Sanguino AM, Gallick GE, Lopez-Berestein G, Sood AK, Ellis LM. Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver. Oncogene. 2008 Dec 04; 27(57):7192-200. PMID: 18806828; PMCID: PMC3199128.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    77. Pan S, Wang R, Zhou X, Corvera J, Kloc M, Sifers R, Gallick GE, Lin SH, Kuang J. Extracellular Alix regulates integrin-mediated cell adhesions and extracellular matrix assembly. EMBO J. 2008 Aug 06; 27(15):2077-90. PMID: 18636094; PMCID: PMC2516883.
      Citations: 13     Fields:    Translation:AnimalsCells
    78. Guan H, Zhou Z, Gallick GE, Jia SF, Morales J, Sood AK, Corey SJ, Kleinerman ES. Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma. Mol Cancer Ther. 2008 Jul; 7(7):1807-16. PMID: 18644993; PMCID: PMC2556989.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    79. Park SI, Zhang J, Phillips KA, Araujo JC, Najjar AM, Volgin AY, Gelovani JG, Kim SJ, Wang Z, Gallick GE. Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model. Cancer Res. 2008 May 01; 68(9):3323-33. PMID: 18451159.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    80. Mandal M, Myers JN, Lippman SM, Johnson FM, Williams MD, Rayala S, Ohshiro K, Rosenthal DI, Weber RS, Gallick GE, El-Naggar AK. Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features. Cancer. 2008 May 01; 112(9):2088-100. PMID: 18327819.
      Citations: 72     Fields:    Translation:HumansCells
    81. Kim MP, Gallick GE. Gemcitabine resistance in pancreatic cancer: picking the key players. Clin Cancer Res. 2008 Mar 01; 14(5):1284-5. PMID: 18316544.
      Citations: 67     Fields:    Translation:HumansAnimals
    82. Kopetz S, Shah AN, Gallick GE. Src continues aging: current and future clinical directions. Clin Cancer Res. 2007 Dec 15; 13(24):7232-6. PMID: 18094400.
      Citations: 57     Fields:    Translation:HumansAnimals
    83. Dorfleutner A, Stehlik C, Zhang J, Gallick GE, Flynn DC. AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB-231 breast cancer cells. J Cell Physiol. 2007 Dec; 213(3):740-9. PMID: 17520695.
      Citations: 31     Fields:    Translation:HumansCells
    84. Liu JL, Mao Z, LaFortune TA, Alonso MM, Gallick GE, Fueyo J, Yung WK. Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade. Cancer Res. 2007 Nov 15; 67(22):11054-63. PMID: 18006852.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    85. Johnson FM, Gallick GE. SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy. Anticancer Agents Med Chem. 2007 Nov; 7(6):651-9. PMID: 18045060.
      Citations: 53     Fields:    Translation:HumansCells
    86. Shah AN, Summy JM, Zhang J, Park SI, Parikh NU, Gallick GE. Development and characterization of gemcitabine-resistant pancreatic tumor cells. Ann Surg Oncol. 2007 Dec; 14(12):3629-37. PMID: 17909916.
      Citations: 226     Fields:    Translation:HumansCells
    87. Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA, Dorfleutner A, Flynn DC, Gallick GE. AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts. J Clin Invest. 2007 Oct; 117(10):2962-73. PMID: 17885682; PMCID: PMC1978423.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    88. Park SI, Shah AN, Zhang J, Gallick GE. Regulation of angiogenesis and vascular permeability by Src family kinases: opportunities for therapeutic treatment of solid tumors. Expert Opin Ther Targets. 2007 Sep; 11(9):1207-17. PMID: 17845146.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    89. Nilsson MB, Armaiz-Pena G, Takahashi R, Lin YG, Trevino J, Li Y, Jennings N, Arevalo J, Lutgendorf SK, Gallick GE, Sanguino AM, Lopez-Berestein G, Cole SW, Sood AK. Stress hormones regulate interleukin-6 expression by human ovarian carcinoma cells through a Src-dependent mechanism. J Biol Chem. 2007 Oct 12; 282(41):29919-26. PMID: 17716980.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    90. Estrella VC, Eder AM, Liu S, Pustilnik TB, Tabassam FH, Claret FX, Gallick GE, Mills GB, Wiener JR. Lysophosphatidic acid induction of urokinase plasminogen activator secretion requires activation of the p38MAPK pathway. Int J Oncol. 2007 Aug; 31(2):441-9. PMID: 17611702.
      Citations: 15     Fields:    Translation:HumansCells
    91. Shah AN, Gallick GE. Src, chemoresistance and epithelial to mesenchymal transition: are they related? Anticancer Drugs. 2007 Apr; 18(4):371-5. PMID: 17351389.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    92. Wang R, He G, Nelman-Gonzalez M, Ashorn CL, Gallick GE, Stukenberg PT, Kirschner MW, Kuang J. Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition. Cell. 2007 Mar 23; 128(6):1119-32. PMID: 17382881.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    93. Herynk MH, Zhang J, Parikh NU, Gallick GE. Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells. J Exp Ther Oncol. 2007; 6(3):205-17. PMID: 17552361.
      Citations: 12     Fields:    Translation:HumansCells
    94. Minard ME, Ellis LM, Gallick GE. Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. Clin Exp Metastasis. 2006; 23(5-6):301-13. PMID: 17086355.
      Citations: 49     Fields:    Translation:HumansCells
    95. Landen CN, Lu C, Han LY, Coffman KT, Bruckheimer E, Halder J, Mangala LS, Merritt WM, Lin YG, Gao C, Schmandt R, Kamat AA, Li Y, Thaker P, Gershenson DM, Parikh NU, Gallick GE, Kinch MS, Sood AK. Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer. J Natl Cancer Inst. 2006 Nov 01; 98(21):1558-70. PMID: 17077358.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    96. Pan S, Wang R, Zhou X, He G, Koomen J, Kobayashi R, Sun L, Corvera J, Gallick GE, Kuang J. Involvement of the conserved adaptor protein Alix in actin cytoskeleton assembly. J Biol Chem. 2006 Nov 10; 281(45):34640-50. PMID: 16966331.
      Citations: 36     Fields:    Translation:HumansCells
    97. Han LY, Landen CN, Trevino JG, Halder J, Lin YG, Kamat AA, Kim TJ, Merritt WM, Coleman RL, Gershenson DM, Shakespeare WC, Wang Y, Sundaramoorth R, Metcalf CA, Dalgarno DC, Sawyer TK, Gallick GE, Sood AK. Antiangiogenic and antitumor effects of SRC inhibition in ovarian carcinoma. Cancer Res. 2006 Sep 01; 66(17):8633-9. PMID: 16951177; PMCID: PMC3202609.
      Citations: 44     Fields:    Translation:HumansCells
    98. Yang L, Avila H, Wang H, Trevino J, Gallick GE, Kitadai Y, Sasaki T, Boyd DD. Plasticity in urokinase-type plasminogen activator receptor (uPAR) display in colon cancer yields metastable subpopulations oscillating in cell surface uPAR density--implications in tumor progression. Cancer Res. 2006 Aug 15; 66(16):7957-67. PMID: 16912170.
      Citations: 6     Fields:    Translation:HumansCells
    99. Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE. Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. Angiogenesis. 2006; 9(2):101-10. PMID: 16871430.
      Citations: 21     Fields:    Translation:HumansCells
    100. Bauer TW, Somcio RJ, Fan F, Liu W, Johnson M, Lesslie DP, Evans DB, Gallick GE, Ellis LM. Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells. Mol Cancer Ther. 2006 Jul; 5(7):1676-82. PMID: 16891453.
      Citations: 47     Fields:    Translation:HumansCells
    101. Baker CH, Trevino JG, Summy JM, Zhang F, Caron A, Nesbit M, Gallick GE, Fidler IJ. Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice. Int J Oncol. 2006 Jul; 29(1):125-38. PMID: 16773192.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    102. Lesslie DP, Summy JM, Parikh NU, Fan F, Trevino JG, Sawyer TK, Metcalf CA, Shakespeare WC, Hicklin DJ, Ellis LM, Gallick GE. Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases. Br J Cancer. 2006 Jun 05; 94(11):1710-7. PMID: 16685275; PMCID: PMC2361330.
      Citations: 39     Fields:    Translation:HumansCells
    103. Trevino JG, Summy JM, Gallick GE. SRC inhibitors as potential therapeutic agents for human cancers. Mini Rev Med Chem. 2006 Jun; 6(6):681-7. PMID: 16787379.
      Citations: 14     Fields:    Translation:Humans
    104. Trevino JG, Summy JM, Lesslie DP, Parikh NU, Hong DS, Lee FY, Donato NJ, Abbruzzese JL, Baker CH, Gallick GE. Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model. Am J Pathol. 2006 Mar; 168(3):962-72. PMID: 16507911; PMCID: PMC1606527.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    105. Summy JM, Gallick GE. Treatment for advanced tumors: SRC reclaims center stage. Clin Cancer Res. 2006 Mar 01; 12(5):1398-401. PMID: 16533761.
      Citations: 78     Fields:    Translation:HumansCells
    106. Summy JM, Trevino JG, Lesslie DP, Baker CH, Shakespeare WC, Wang Y, Sundaramoorthi R, Metcalf CA, Keats JA, Sawyer TK, Gallick GE. AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes. Mol Cancer Ther. 2005 Dec; 4(12):1900-11. PMID: 16373705.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    107. Summy JM, Trevino JG, Baker CH, Gallick GE. c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK. Pancreas. 2005 Oct; 31(3):263-74. PMID: 16163059.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    108. Inoue S, Branch CD, Gallick GE, Chada S, Ramesh R. Inhibition of Src kinase activity by Ad-mda7 suppresses vascular endothelial growth factor expression in prostate carcinoma cells. Mol Ther. 2005 Oct; 12(4):707-15. PMID: 16054437.
      Citations: 23     Fields:    Translation:HumansCells
    109. Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, Gallick GE. Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis. Cancer Res. 2005 Aug 15; 65(16):7214-22. PMID: 16103072.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    110. Cabioglu N, Summy J, Miller C, Parikh NU, Sahin AA, Tuzlali S, Pumiglia K, Gallick GE, Price JE. CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation. Cancer Res. 2005 Aug 01; 65(15):6493-7. PMID: 16061624.
      Citations: 66     Fields:    Translation:HumansCells
    111. Wey JS, Gray MJ, Fan F, Belcheva A, McCarty MF, Stoeltzing O, Somcio R, Liu W, Evans DB, Klagsbrun M, Gallick GE, Ellis LM. Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells. Br J Cancer. 2005 Jul 25; 93(2):233-41. PMID: 15956974; PMCID: PMC2361553.
      Citations: 42     Fields:    Translation:HumansCells
    112. Liu JL, Sheng X, Hortobagyi ZK, Mao Z, Gallick GE, Yung WK. Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation. Mol Cell Biol. 2005 Jul; 25(14):6211-24. PMID: 15988030; PMCID: PMC1168816.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    113. Bauer TW, Fan F, Liu W, Johnson M, Parikh NU, Parry GC, Callahan J, Mazar AP, Gallick GE, Ellis LM. Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor. Ann Surg. 2005 May; 241(5):748-56; discussion 756-8. PMID: 15849510; PMCID: PMC1357129.
      Citations: 23     Fields:    Translation:HumansCells
    114. Gray MJ, Wey JS, Belcheva A, McCarty MF, Trevino JG, Evans DB, Ellis LM, Gallick GE. Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors. Cancer Res. 2005 May 01; 65(9):3664-70. PMID: 15867361.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    115. Gray MJ, Zhang J, Ellis LM, Semenza GL, Evans DB, Watowich SS, Gallick GE. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene. 2005 Apr 28; 24(19):3110-20. PMID: 15735682.
      Citations: 153     Fields:    Translation:HumansCells
    116. Minard ME, Herynk MH, Collard JG, Gallick GE. The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model. Oncogene. 2005 Apr 07; 24(15):2568-73. PMID: 15735692.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    117. Camp ER, Summy J, Bauer TW, Liu W, Gallick GE, Ellis LM. Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor. Clin Cancer Res. 2005 Jan 01; 11(1):397-405. PMID: 15671571.
      Citations: 72     Fields:    Translation:HumansCells
    118. Gallick GE. SRC as a potential therapeutic target in solid tumor oncology. Clin Adv Hematol Oncol. 2004 Jul; 2(7):435-7. PMID: 16163218.
      Citations: 3     Fields:    Translation:HumansCells
    119. Minard ME, Kim LS, Price JE, Gallick GE. The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression. Breast Cancer Res Treat. 2004 Mar; 84(1):21-32. PMID: 14999151.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    120. Boyd DD, Wang H, Avila H, Parikh NU, Kessler H, Magdolen V, Gallick GE. Combination of an SRC kinase inhibitor with a novel pharmacological antagonist of the urokinase receptor diminishes in vitro colon cancer invasiveness. Clin Cancer Res. 2004 Feb 15; 10(4):1545-55. PMID: 14977859.
      Citations: 11     Fields:    Translation:HumansCells
    121. Summy JM, Gallick GE. Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev. 2003 Dec; 22(4):337-58. PMID: 12884910.
      Citations: 348     Fields:    Translation:HumansCells
    122. Kim SJ, Johnson M, Koterba K, Herynk MH, Uehara H, Gallick GE. Reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model. Clin Cancer Res. 2003 Nov 01; 9(14):5161-70. PMID: 14613995.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    123. Liu W, Reinmuth N, Stoeltzing O, Parikh AA, Tellez C, Williams S, Jung YD, Fan F, Takeda A, Akagi M, Bar-Eli M, Gallick GE, Ellis LM. Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways. Cancer Res. 2003 Jul 01; 63(13):3632-6. PMID: 12839952.
      Citations: 43     Fields:    Translation:HumansCells
    124. Herynk MH, Stoeltzing O, Reinmuth N, Parikh NU, Abounader R, Laterra J, Radinsky R, Ellis LM, Gallick GE. Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells. Cancer Res. 2003 Jun 01; 63(11):2990-6. PMID: 12782608.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    125. Reinmuth N, Liu W, Ahmad SA, Fan F, Stoeltzing O, Parikh AA, Bucana CD, Gallick GE, Nickols MA, Westlin WF, Ellis LM. Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice. Cancer Res. 2003 May 01; 63(9):2079-87. PMID: 12727823.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    126. Boyd DD, Kim SJ, Wang H, Jones TR, Gallick GE. A urokinase-derived peptide (A6) increases survival of mice bearing orthotopically grown prostate cancer and reduces lymph node metastasis. Am J Pathol. 2003 Feb; 162(2):619-26. PMID: 12547719; PMCID: PMC1851141.
      Citations: 20     Fields:    Translation:Animals
    127. Donato NJ, Wu JY, Stapley J, Gallick G, Lin H, Arlinghaus R, Talpaz M. BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571. Blood. 2003 Jan 15; 101(2):690-8. PMID: 12509383.
      Citations: 213     Fields:    Translation:HumansCells
    128. Herynk MH, Tsan R, Radinsky R, Gallick GE. Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin. Clin Exp Metastasis. 2003; 20(4):291-300. PMID: 12856716.
      Citations: 20     Fields:    Translation:HumansCells
    129. Wiener JR, Windham TC, Estrella VC, Parikh NU, Thall PF, Deavers MT, Bast RC, Mills GB, Gallick GE. Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers. Gynecol Oncol. 2003 Jan; 88(1):73-9. PMID: 12504632.
      Citations: 70     Fields:    Translation:HumansCells
    130. Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE. Src activation regulates anoikis in human colon tumor cell lines. Oncogene. 2002 Nov 07; 21(51):7797-807. PMID: 12420216.
      Citations: 73     Fields:    Translation:HumansCells
    131. Reinmuth N, Fan F, Liu W, Parikh AA, Stoeltzing O, Jung YD, Bucana CD, Radinsky R, Gallick GE, Ellis LM. Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer. Lab Invest. 2002 Oct; 82(10):1377-89. PMID: 12379772.
      Citations: 58     Fields:    Translation:HumansCells
    132. Gallick GE, Nicolson GL, Haier J. Src protein kinase pp60c-src influences adhesion stabilization of HT-29 colon carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow. J Exp Ther Oncol. 2002 Jul-Aug; 2(4):237-45. PMID: 12416028.
      Citations: 3     Fields:    Translation:HumansCells
    133. Davies MA, Kim SJ, Parikh NU, Dong Z, Bucana CD, Gallick GE. Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clin Cancer Res. 2002 Jun; 8(6):1904-14. PMID: 12060635.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    134. Aligayer H, Boyd DD, Heiss MM, Abdalla EK, Curley SA, Gallick GE. Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis. Cancer. 2002 Jan 15; 94(2):344-51. PMID: 11900220.
      Citations: 111     Fields:    Translation:HumansCells
    135. Solorzano CC, Jung YD, Bucana CD, McConkey DJ, Gallick GE, McMahon G, Ellis LM. In vivo intracellular signaling as a marker of antiangiogenic activity. Cancer Res. 2001 Oct 01; 61(19):7048-51. PMID: 11585733.
      Citations: 9     Fields:    Translation:HumansCells
    136. Reinmuth N, Liu W, Jung YD, Ahmad SA, Shaheen RM, Fan F, Bucana CD, McMahon G, Gallick GE, Ellis LM. Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival. FASEB J. 2001 May; 15(7):1239-41. PMID: 11344100.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    137. Beresford SA, Davies MA, Gallick GE, Donato NJ. Differential effects of phosphatidylinositol-3/Akt-kinase inhibition on apoptotic sensitization to cytokines in LNCaP and PCc-3 prostate cancer cells. J Interferon Cytokine Res. 2001 May; 21(5):313-22. PMID: 11429162.
      Citations: 5     Fields:    Translation:HumansCells
    138. Jung YD, Kim MS, Shin BA, Chay KO, Ahn BW, Liu W, Bucana CD, Gallick GE, Ellis LM. EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. Br J Cancer. 2001 Mar 23; 84(6):844-50. PMID: 11259102; PMCID: PMC2363808.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    139. Jung YD, Liu W, Reinmuth N, Ahmad SA, Fan F, Gallick GE, Ellis LM. Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway. Angiogenesis. 2001; 4(2):155-62. PMID: 11806247.
      Citations: 41     Fields:    Translation:HumansCells
    140. Ellis LM, Gallick GE. Promiscuous transcription of vascular endothelial growth factor and survival of tumors. J Natl Cancer Inst. 2000 Jul 05; 92(13):1030-1. PMID: 10880538.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    141. Gallick GE. Tyrosine kinase inhibitors for suppression of tumorigenic growth of Ras-transformed cells: PAK-ing in the signals. Cancer J. 2000 Jul-Aug; 6(4):217-9. PMID: 11038141.
      Citations:    Fields:    Translation:AnimalsCells
    142. Jung YD, Nakano K, Liu W, Gallick GE, Ellis LM. Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells. Cancer Res. 1999 Oct 01; 59(19):4804-7. PMID: 10519388.
      Citations: 30     Fields:    Translation:HumansCells
    143. Ramdas L, Bunnin BA, Plunkett MJ, Sun G, Ellman J, Gallick G, Budde RJ. Benzodiazepine compounds as inhibitors of the src protein tyrosine kinase: screening of a combinatorial library of 1,4-benzodiazepines. Arch Biochem Biophys. 1999 Aug 15; 368(2):394-400. PMID: 10441393.
      Citations: 3     Fields:    Translation:HumansCells
    144. Wiener JR, Nakano K, Kruzelock RP, Bucana CD, Bast RC, Gallick GE. Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model. Clin Cancer Res. 1999 Aug; 5(8):2164-70. PMID: 10473101.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    145. Allgayer H, Wang H, Gallick GE, Crabtree A, Mazar A, Jones T, Kraker AJ, Boyd DD. Transcriptional induction of the urokinase receptor gene by a constitutively active Src. Requirement of an upstream motif (-152/-135) bound with Sp1. J Biol Chem. 1999 Jun 25; 274(26):18428-37. PMID: 10373450.
      Citations: 12     Fields:    Translation:HumansCells
    146. Marchetti D, Parikh N, Sudol M, Gallick GE. Stimulation of the protein tyrosine kinase c-Yes but not c-Src by neurotrophins in human brain-metastatic melanoma cells. Oncogene. 1998 Jun 25; 16(25):3253-60. PMID: 9681823.
      Citations: 20     Fields:    Translation:HumansCells
    147. Ellis LM, Staley CA, Liu W, Fleming RY, Parikh NU, Bucana CD, Gallick GE. Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src. J Biol Chem. 1998 Jan 09; 273(2):1052-7. PMID: 9422768.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    148. Fleming RY, Ellis LM, Parikh NU, Liu W, Staley CA, Gallick GE. Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by activity of src kinase. Surgery. 1997 Aug; 122(2):501-7. PMID: 9288158.
      Citations: 9     Fields:    Translation:HumansCells
    149. Han NM, Fleming RY, Curley SA, Gallick GE. Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation. Ann Surg Oncol. 1997 Apr-May; 4(3):264-8. PMID: 9142389.
      Citations: 11     Fields:    Translation:Humans
    150. Staley CA, Parikh NU, Gallick GE. Decreased tumorigenicity of a human colon adenocarcinoma cell line by an antisense expression vector specific for c-Src. Cell Growth Differ. 1997 Mar; 8(3):269-74. PMID: 9056668.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    151. Han NM, Curley SA, Gallick GE. Differential activation of pp60(c-src) and pp62(c-yes) in human colorectal carcinoma liver metastases. Clin Cancer Res. 1996 Aug; 2(8):1397-404. PMID: 9816313.
      Citations: 22     Fields:    Translation:HumansCells
    152. Ramdas L, Obeyesekere NU, McMurray JS, Gallick GE, Seifert WE, Budde RJ. A tyrphostin-derived inhibitor of protein tyrosine kinases: isolation and characterization. Arch Biochem Biophys. 1995 Nov 10; 323(2):237-42. PMID: 7487083.
      Citations:    Fields:    Translation:HumansCells
    153. Novotny-Smith CL, Zorbas MA, Mcisaac AM, Irimura T, Boman BM, Yeoman LC, Gallick GE. Down-modulation of epidermal growth factor receptor accompanies TNF-induced differentiation of the DiFi human adenocarcinoma cell line toward a goblet-like phenotype. J Cell Physiol. 1993 Nov; 157(2):253-62. PMID: 8227158.
      Citations: 3     Fields:    Translation:HumansCells
    154. Saya H, Lee PS, Nishi T, Izawa I, Nakajima M, Gallick GE, Levin VA. Bacterial expression of an active tyrosine kinase from a protein A/truncated c-src fusion protein. FEBS Lett. 1993 Jul 26; 327(2):224-30. PMID: 7687570.
      Citations: 2     Fields:    Translation:Cells
    155. Untawale S, Zorbas MA, Hodgson CP, Coffey RJ, Gallick GE, North SM, Wildrick DM, Olive M, Blick M, Yeoman LC, et al. Transforming growth factor-alpha production and autoinduction in a colorectal carcinoma cell line (DiFi) with an amplified epidermal growth factor receptor gene. Cancer Res. 1993 Apr 01; 53(7):1630-6. PMID: 8453634.
      Citations: 11     Fields:    Translation:HumansCells
    156. Termuhlen PM, Curley SA, Talamonti MS, Saboorian MH, Gallick GE. Site-specific differences in pp60c-src activity in human colorectal metastases. J Surg Res. 1993 Apr; 54(4):293-8. PMID: 7687314.
      Citations: 25     Fields:    Translation:Humans
    157. Talamonti MS, Roh MS, Curley SA, Gallick GE. Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer. J Clin Invest. 1993 Jan; 91(1):53-60. PMID: 7678609; PMCID: PMC329994.
      Citations: 118     Fields:    Translation:HumansCells
    158. Jessup JM, Gallick GE. The biology of colorectal carcinoma. Curr Probl Cancer. 1992 Sep-Oct; 16(5):261-328. PMID: 1337732.
      Citations: 7     Fields:    Translation:Humans
    159. Nicolson GL, Gallick GE, Spohn WH, Lembo TM, Tainsky MA. Transfection of activated c-H-rasEJ/pSV2neo or pSV2neo genes into rat mammary cells: rapid stimulation of clonal diversification of spontaneous metastatic and cell-surface properties. Oncogene. 1992 Jun; 7(6):1127-35. PMID: 1594244.
      Citations: 6     Fields:    Translation:AnimalsCells
    160. Novotny-Smith CL, Gallick GE. Growth inhibition of human colorectal carcinoma cell lines by tumor necrosis factor-alpha correlates with reduced activity of pp60c-src. J Immunother (1991). 1992 Apr; 11(3):159-68. PMID: 1381217.
      Citations: 2     Fields:    Translation:HumansCells
    161. Putnam EA, Yen N, Gallick GE, Steck PA, Fang K, Akpakip B, Gazdar AF, Roth JA. Autocrine growth stimulation by transforming growth factor-alpha in human non-small cell lung cancer. Surg Oncol. 1992 Feb; 1(1):49-60. PMID: 1341235.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    162. Kim JS, Steck PA, Gallick GE, Lee JS, Blick M, Hong WK, Lotan R. Suppression by retinoic acid of epidermal growth factor receptor autophosphorylation and glycosylation in cultured human head and neck squamous carcinoma cells. J Natl Cancer Inst Monogr. 1992; (13):101-10. PMID: 1389683.
      Citations: 3     Fields:    Translation:HumansCells
    163. Garcia R, Parikh NU, Saya H, Gallick GE. Effect of herbimycin A on growth and pp60c-src activity in human colon tumor cell lines. Oncogene. 1991 Nov; 6(11):1983-9. PMID: 1719464.
      Citations: 11     Fields:    Translation:HumansCells
    164. Chiao PJ, Kannan P, Yim SO, Krizman DB, Wu TA, Gallick GE, Tainsky MA. Susceptibility to ras oncogene transformation is coregulated with signal transduction through growth factor receptors. Oncogene. 1991 May; 6(5):713-20. PMID: 1646984.
      Citations: 5     Fields:    Translation:HumansCells
    165. Gross ME, Zorbas MA, Danels YJ, Garcia R, Gallick GE, Olive M, Brattain MG, Boman BM, Yeoman LC. Cellular growth response to epidermal growth factor in colon carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous polyposis patient. Cancer Res. 1991 Mar 01; 51(5):1452-9. PMID: 1847663.
      Citations: 28     Fields:    Translation:HumansCells
    166. Nicolson GL, Gallick GE, Dulski KM, Spohn WH, Lembo TM, Tainsky MA. Lack of correlation between intercellular junctional communication, p21rasEJ expression, and spontaneous metastatic properties of rat mammary cells after transfection with c-H-rasEJ or neo genes. Oncogene. 1990 May; 5(5):747-53. PMID: 2189108.
      Citations: 11     Fields:    Translation:AnimalsCells
    167. Donato NJ, Gallick GE, Steck PA, Rosenblum MG. Tumor necrosis factor modulates epidermal growth factor receptor phosphorylation and kinase activity in human tumor cells. Correlation with cytotoxicity. J Biol Chem. 1989 Dec 05; 264(34):20474-81. PMID: 2555361.
      Citations: 15     Fields:    Translation:HumansCells
    168. Donato NJ, Ince C, Rosenblum MG, Gallick GE. Early events in the antiproliferative action of tumor necrosis factor are similar to the early events in epidermal growth factor growth stimulation. J Cell Biochem. 1989 Nov; 41(3):139-57. PMID: 2482293.
      Citations: 4     Fields:    Translation:Cells
    169. Maxwell SA, Sacks PG, Gutterman JU, Gallick GE. Epidermal growth factor receptor protein-tyrosine kinase activity in human cell lines established from squamous carcinomas of the head and neck. Cancer Res. 1989 Mar 01; 49(5):1130-7. PMID: 2783883.
      Citations: 10     Fields:    Translation:HumansCells
    170. Weber RS, Pathak S, Frankenthaler R, Gallick GE, Sacks PG. Effect of epidermal growth factor (EGF) on a newly established head and neck squamous carcinoma cell line. Otolaryngol Head Neck Surg. 1988 Dec; 99(6):567-73. PMID: 3148118.
      Citations: 3     Fields:    Translation:HumansCells
    171. Lichtner RB, Gallick GE, Nicolson GL. Pyrimido-pyrimidine modulation of EGF growth-promoting activity and p21ras expression in rat mammary adenocarcinoma cells. J Cell Physiol. 1988 Nov; 137(2):285-92. PMID: 3056958.
      Citations: 3     Fields:    Translation:Animals
    172. Tsuchiya H, Epstein J, Selvanayagam P, Dedman JR, Gallick G, Alexanian R, Barlogie B. Correlated flow cytometric analysis of H-ras p21 and nuclear DNA in multiple myeloma. Blood. 1988 Aug; 72(2):796-800. PMID: 3042048.
      Citations: 5     Fields:    Translation:HumansCells
    173. Sacks PG, Parnes SM, Gallick GE, Mansouri Z, Lichtner R, Satya-Prakash KL, Pathak S, Parsons DF. Establishment and characterization of two new squamous cell carcinoma cell lines derived from tumors of the head and neck. Cancer Res. 1988 May 15; 48(10):2858-66. PMID: 2452013.
      Citations: 41     Fields:    Translation:HumansCells
    174. LaBiche RA, Yoshida M, Gallick GE, Irimura T, Robberson DL, Klostergaard J, Nicolson GL. Gene expression and tumor cell escape from host effector mechanisms in murine large cell lymphoma. J Cell Biochem. 1988 Apr; 36(4):393-403. PMID: 3379107.
      Citations: 4     Fields:    Translation:AnimalsCells
    175. Lai CN, Gallick GE, Maxwell SA, Brinkley BR, Becker FF. Potassium inhibition of transforming protein P85gag-mos and reversal of the transformed phenotype in 6m2 cells. J Cell Physiol. 1988 Mar; 134(3):445-52. PMID: 2965157.
      Citations: 1     Fields:    Translation:AnimalsCells
    176. Ro J, North SM, Gallick GE, Hortobagyi GN, Gutterman JU, Blick M. Amplified and overexpressed epidermal growth factor receptor gene in uncultured primary human breast carcinoma. Cancer Res. 1988 Jan 01; 48(1):161-4. PMID: 3334990.
      Citations: 28     Fields:    Translation:Humans
    177. Yoshida M, Gallick GE, Irimura T, Nicolson GL. Modification of cell surface glycoproteins, macrophage cytostasis, and blood-borne metastatic properties of the murine RAW117 large cell lymphoma by virus superinfection. Cancer Res. 1987 May 15; 47(10):2558-62. PMID: 3567891.
      Citations: 2     Fields:    Translation:AnimalsCells
    178. Maxwell SA, Kurzrock R, Parsons SJ, Talpaz M, Gallick GE, Kloetzer WS, Arlinghaus RB, Kouttab NM, Keating MJ, Gutterman JU. Analysis of P210bcr-abl tyrosine protein kinase activity in various subtypes of Philadelphia chromosome-positive cells from chronic myelogenous leukemia patients. Cancer Res. 1987 Mar 15; 47(6):1731-9. PMID: 2434223.
      Citations: 11     Fields:    Translation:HumansCells
    179. Liang JC, Kurzrock R, Gutterman JU, Gallick GE. Trisomy 12 correlates with elevated expression of p21 ras in a human adenosquamous carcinoma of the lung. Cancer Genet Cytogenet. 1986 Oct; 23(2):183-8. PMID: 3530433.
      Citations: 1     Fields:    Translation:HumansCells
    180. Kurzrock R, Gallick GE, Gutterman JU. Differential expression of p21ras gene products among histological subtypes of fresh primary human lung tumors. Cancer Res. 1986 Mar; 46(3):1530-4. PMID: 3002619.
      Citations: 19     Fields:    Translation:Humans
    181. Steck PA, Gallick GE, Maxwell SA, Kloetzer WS, Arlinghaus RB, Moser RP, Gutterman JU, Yung WK. Expression of epidermal growth factor receptor and associated glycoprotein on cultured human brain tumor cells. J Cell Biochem. 1986; 32(1):1-10. PMID: 3533968.
      Citations: 8     Fields:    Translation:HumansCells
    182. Gallick GE, Sacks PG, Maxwell SA, Steck PA, Gutterman JU. Head and neck squamous cell carcinoma cell lines as a model system for the study of oncogene expression during tumor progression and metastasis. Prog Clin Biol Res. 1986; 212:97-111. PMID: 3012576.
      Citations:    Fields:    Translation:HumansCells
    183. Gallick GE, Kurzrock R, Kloetzer WS, Arlinghaus RB, Gutterman JU. Expression of p21ras in fresh primary and metastatic human colorectal tumors. Proc Natl Acad Sci U S A. 1985 Mar; 82(6):1795-9. PMID: 3885218; PMCID: PMC397359.
      Citations: 46     Fields:    Translation:Humans
    184. Stanker LH, Horn JP, Gallick GE, Kloetzer WS, Murphy EC, Blair DG, Arlinghaus RB. Gag-mos Polyproteins encoded by variants of the Moloney strain of mouse sarcoma virus. Virology. 1983 Apr 15; 126(1):336-47. PMID: 6302990.
      Citations: 6     Fields:    Translation:AnimalsCells
    185. Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells. Oncotarget. 6:10175-10194.
    186. The combination of serum insulin, osteopontin, and hepatocyte growth factor predicts time to castration-resistant progression in androgen dependent metastatic prostate cancer- an exploratory study. BMC Cancer. 16.
    187. Nonreceptor tyrosine kinases and their roles in cancer. 39-53.
    188. Erratum. Nature Communications. 4.
    189. P85(gag-mos) encoded by ts110 Moloney murine sarcoma virus. Journal of General Virology. 64:2203-2211.
    190. Integrating murine and clinical trials with cabozantinib to understand roles of MET and VEGFR2 as targets for growth inhibition of prostate cancer. Clinical Cancer Research. 22:107-121.
    191. Preclinical mouse models of human prostate cancer and their utility in drug discovery. Current Protocols in Pharmacology.
    192. Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer. Investigational New Drugs.
    193. Molecular alterations in benign and premalignant colorectal tumors. Cancer Bulletin. 47:366-369.
    194. Expression of p21(ras) in fresh primary human lung tumors.
    195. Discovery, development, and testing of substrates and inhibitors of pp60c-SRC . Pharmaceutical Biology. 33:27-34.
    196. RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival. Molecular Cancer Research. 13:348-357.
    197. Molecular alterations during colon tumorigenesis. Cancer Bulletin. 46:296-302.
    198. Discovery, development, and testing of substrates and inhibitors of pp60(c-src). International Journal of Pharmacognosy. 33:27-34.
    199. Identification of bone-derived factors conferring de novo therapeutic resistance in metastatic prostate cancer. Cancer Research. 75:4949-4959.
    200. The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK<sup>+</sup> T-cell lymphoma. Molecular Cancer. 14.
    201. Development and progression of human colon cancer. Cancer Bulletin. 44:321-326.
    202. Response. Journal of the National Cancer Institute. 104:717.
    203. Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy. Oncotarget. 6:29161-29177.
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