PETER FRIEDL

TitleProfessor
InstitutionMD Anderson
DepartmentGenitourinary Medical Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tran AT, Wisniewski EO, Mistriotis P, Stoletov K, Parlani M, Amitrano A, Ifemembi B, Lee SJ, Bera K, Zhang Y, Tuntithavornwat S, Afthinos A, Kiepas A, Jamieson JJ, Zuo Y, Habib D, Wu PH, Martin SS, Gerecht S, Gu L, Lewis JD, Kalab P, Friedl P, Konstantopoulos K. Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion. Res Sq. 2024 Jan 10. PMID: 38260442; PMCID: PMC10802709.
      Citations:    
    2. Beunk L, Wen N, van Helvert S, Bekker B, Ran L, Kang R, Paulat T, Syga S, Deutsch A, Friedl P, Wolf K. Cell jamming in a collagen-based interface assay is tuned by collagen density and proteolysis. J Cell Sci. 2023 12 01; 136(23). PMID: 37987169; PMCID: PMC10753497.
      Citations:    Fields:    Translation:HumansCells
    3. Weiss F, Atlasy N, van Reijmersdal V, Stunnenberg H, Hulsbergen-Veelken C, Friedl P. 3D spheroid culture to examine adaptive therapy response in invading tumor cells. In Vitro Model. 2022; 1(6):463-471. PMID: 37096022; PMCID: PMC10119213.
      Citations:    
    4. Law RA, Kiepas A, Desta HE, Perez Ipi?a E, Parlani M, Lee SJ, Yankaskas CL, Zhao R, Mistriotis P, Wang N, Gu Z, Kalab P, Friedl P, Camley BA, Konstantopoulos K. Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement. Sci Adv. 2023 01 13; 9(2):eabq6480. PMID: 36630496; PMCID: PMC9833664.
      Citations: 1     Fields:    Translation:HumansCells
    5. Parlani M, Bedell ML, Mikos AG, Friedl P, Dondossola E. Dissecting the recruitment and self-organization of aSMA-positive fibroblasts in the foreign body response. Sci Adv. 2022 Dec 21; 8(51):eadd0014. PMID: 36542704; PMCID: PMC9770965.
      Citations:    Fields:    
    6. Slaats J, Wagena E, Smits D, Berends AA, Peters E, Bakker GJ, van Erp M, Weigelin B, Adema GJ, Friedl P. Adenosine A2a Receptor Antagonism Restores Additive Cytotoxicity by Cytotoxic T Cells in Metabolically Perturbed Tumors. Cancer Immunol Res. 2022 12 02; 10(12):1462-1474. PMID: 36162129; PMCID: PMC9716258.
      Citations: 4     Fields:    Translation:HumansCells
    7. Parlani M, Jorgez C, Friedl P. Plasticity of cancer invasion and energy metabolism. Trends Cell Biol. 2023 05; 33(5):388-402. PMID: 36328835; PMCID: PMC10368441.
      Citations: 3     Fields:    Translation:Humans
    8. Wolf K, Friedl P. Steering from the rear. Nat Mater. 2022 Oct; 21(10):1104-1105. PMID: 36151462.
      Citations:    Fields:    
    9. Weigelin B, Friedl P. T cell-mediated additive cytotoxicity - death by multiple bullets. Trends Cancer. 2022 Dec; 8(12):980-987. PMID: 35965200.
      Citations:    
    10. Beunk L, Bakker GJ, van Ens D, Bugter J, Gal F, Svoren M, Friedl P, Wolf K. Actomyosin contractility requirements and reciprocal cell-tissue mechanics for cancer cell invasion through collagen-based channels. Eur Phys J E Soft Matter. 2022 May 16; 45(5):48. PMID: 35575822; PMCID: PMC9110550.
      Citations:    Fields:    Translation:HumansCells
    11. Bakker GJ, Weischer S, Heidelin J, Andresen V, Beutler M, Friedl P, Ferrer Ortas J, Beaurepaire E. Intravital deep-tumor single-beam 3-photon, 4-photon, and harmonic microscopy. Elife. 2022 02 15; 11. PMID: 35166669; PMCID: PMC8849342.
      Citations: 1     Fields:    Translation:AnimalsCells
    12. Weiss F, Lauffenburger D, Friedl P. Towards targeting of shared mechanisms of cancer metastasis and therapy resistance. Nat Rev Cancer. 2022 03; 22(3):157-173. PMID: 35013601; PMCID: PMC10399972.
      Citations: 6     Fields:    Translation:HumansCells
    13. Te Boekhorst V, Jiang L, Meerlo M, Dunkel G, Durst FC, Yang Y, Levine H, Burgering BMT, Friedl P, M?hlen M. Calpain-2 regulates hypoxia/HIF-induced plasticity toward amoeboid cancer cell migration and metastasis. Curr Biol. 2022 01 24; 32(2):412-427.e8. PMID: 34883047; PMCID: PMC10439789.
      Citations:    Fields:    Translation:HumansAnimalsCells
    14. Van der Meer JMR, Maas RJA, Guldevall K, Klarenaar K, De Jonge PKJD, Hoogstad-van Evert JS, van der Waart AB, Cany J, Safrit JT, Lee JH, Wagena E, Friedl P, Massuger LF, Schaap NPM, Jansen JH, Hobo W, Dolstra H, ?nfelt B. Correction to: IL-15 superagonist N-803 improves IFN? production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells. Cancer Immunol Immunother. 2021 Nov; 70(11):3367. PMID: 34524494; PMCID: PMC8505330.
      Citations:    Fields:    
    15. Haddad TS, Friedl P, Farahani N, Treanor D, Zlobec I, Nagtegaal I. Tutorial: methods for three-dimensional visualization of archival tissue material. Nat Protoc. 2021 11; 16(11):4945-4962. PMID: 34716449.
      Citations:    Fields:    
    16. Paindelli C, Casarin S, Wang F, Diaz-Gomez L, Zhang J, Mikos AG, Logothetis CJ, Friedl P, Dondossola E. Enhancing 223Ra Treatment Efficacy by Anti-?1 Integrin Targeting. J Nucl Med. 2022 07; 63(7):1039-1045. PMID: 34711616; PMCID: PMC9258579.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    17. Weigelin B, den Boer AT, Wagena E, Broen K, Dolstra H, de Boer RJ, Figdor CG, Textor J, Friedl P. Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity. Nat Commun. 2021 09 01; 12(1):5217. PMID: 34471116; PMCID: PMC8410835.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    18. Slaats J, Dieteren CE, Wagena E, Wolf L, Raaijmakers TK, van der Laak JA, Figdor CG, Weigelin B, Friedl P. Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery. Cancer Immunol Res. 2021 08; 9(8):926-938. PMID: 34226201.
      Citations:    Fields:    Translation:HumansAnimalsCells
    19. Van der Meer JMR, Maas RJA, Guldevall K, Klarenaar K, de Jonge PKJD, Evert JSH, van der Waart AB, Cany J, Safrit JT, Lee JH, Wagena E, Friedl P, Massuger LF, Schaap NPM, Jansen JH, Hobo W, Dolstra H, ?nfelt B. IL-15 superagonist N-803 improves IFN? production and killing of leukemia and ovarian cancer cells by CD34+?progenitor-derived NK cells. Cancer Immunol Immunother. 2021 May; 70(5):1305-1321. PMID: 33140189; PMCID: PMC8053152.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    20. Ilina O, Gritsenko PG, La Porta CAM, Grosser S, Vullings M, Bakker GJ, Bult P, Zapperi S, Friedl P, Syga S, Lippoldt J, Chepizhko O, Starru? J, K?s JA, Deutsch A. Cell-cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion. Nat Cell Biol. 2020 09; 22(9):1103-1115. PMID: 32839548; PMCID: PMC7502685.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    21. Wisniewski EO, Mistriotis P, Bera K, Law RA, Zhang J, Nikolic M, Weiger M, Parlani M, Tuntithavornwat S, Afthinos A, Zhao R, Wirtz D, Kalab P, Scarcelli G, Friedl P, Konstantopoulos K. Dorsoventral polarity directs cell responses to migration track geometries. Sci Adv. 2020 07; 6(31):eaba6505. PMID: 32789173; PMCID: PMC7399493.
      Citations: 9     Fields:    
    22. Friedl P, Preziosi L, Deutsch A, Theraulaz G. Multi-scale analysis and modelling of collective migration in biological systems. Philos Trans R Soc Lond B Biol Sci. 2020 09 14; 375(1807):20190377. PMID: 32713301; PMCID: PMC7423374.
      Citations: 3     Fields:    Translation:Animals
    23. Haeger A, Vullings M, Veelken C, Flucke U, Koehl GE, Hoffman RM, Geissler EK, Friedl P, Alexander S, Kaiser FMP, Hirschberg M, Flentje M, Kissler S. Collective cancer invasion forms an integrin-dependent radioresistant niche. J Exp Med. 2020 01 06; 217(1). PMID: 31658985; PMCID: PMC7037234.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    24. Gritsenko PG, Atlasy N, Dieteren CEJ, Navis AC, Venhuizen JH, Veelken C, Schubert D, Acker-Palmer A, Westerman BA, Wurdinger T, Leenders W, Wesseling P, Stunnenberg HG, Friedl P. p120-catenin-dependent collective brain infiltration by glioma cell networks. Nat Cell Biol. 2020 01; 22(1):97-107. PMID: 31907411; PMCID: PMC6952556.
      Citations: 28     Fields:    Translation:AnimalsCells
    25. Friedl P. Rethinking research into metastasis. Elife. 2019 12 17; 8. PMID: 31845646; PMCID: PMC6917486.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    26. Dondossola E, Casarin S, Paindelli C, De-Juan-Pardo EM, Hutmacher DW, Logothetis CJ, Friedl P. Radium 223-Mediated Zonal Cytotoxicity of Prostate Cancer in Bone. J Natl Cancer Inst. 2019 10 01; 111(10):1042-1050. PMID: 30657953; PMCID: PMC6792112.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    27. Venhuizen JH, Span PN, van den Dries K, Sommer S, Friedl P, Zegers MM. P120 Catenin Isoforms Differentially Associate with Breast Cancer Invasion and Metastasis. Cancers (Basel). 2019 Sep 29; 11(10). PMID: 31569498; PMCID: PMC6826419.
      Citations: 6     
    28. Nevozhay D, Weiger M, Friedl P, Sokolov KV. Spatiotemporally controlled nano-sized third harmonic generation agents. Biomed Opt Express. 2019 Jul 01; 10(7):3301-3316. PMID: 31360600; PMCID: PMC6640828.
      Citations: 3     
    29. Paindelli C, Navone N, Logothetis CJ, Friedl P, Dondossola E. Engineered bone for probing organotypic growth and therapy response of prostate cancer tumoroids in vitro. Biomaterials. 2019 03; 197:296-304. PMID: 30682644; PMCID: PMC7094882.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    30. Venhuizen JH, Sommer S, Span PN, Friedl P, Zegers MM. Differential expression of p120-catenin 1 and 3 isoforms in epithelial tissues. Sci Rep. 2019 01 14; 9(1):90. PMID: 30643202; PMCID: PMC6331582.
      Citations: 3     Fields:    Translation:HumansCells
    31. Odenthal J, Friedl P, Takes RP. Compatibility of CO2 laser surgery and fluorescence detection in head and neck cancer cells. Head Neck. 2019 05; 41(5):1253-1259. PMID: 30549379.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    32. Huda S, Weigelin B, Wolf K, Tretiakov KV, Polev K, Wilk G, Iwasa M, Emami FS, Narojczyk JW, Banaszak M, Soh S, Pilans D, Vahid A, Makurath M, Friedl P, Borisy GG, Kandere-Grzybowska K, Grzybowski BA. L?vy-like movement patterns of metastatic cancer cells revealed in microfabricated systems and implicated in vivo. Nat Commun. 2018 10 31; 9(1):4539. PMID: 30382086; PMCID: PMC6208440.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    33. Beunk L, Brown K, Nagtegaal I, Friedl P, Wolf K. Cancer invasion into musculature: Mechanics, molecules and implications. Semin Cell Dev Biol. 2019 09; 93:36-45. PMID: 30009945; PMCID: PMC6399078.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    34. Ilina O, Campanello L, Gritsenko PG, Vullings M, Wang C, Bult P, Losert W, Friedl P. Intravital microscopy of collective invasion plasticity in breast cancer. Dis Model Mech. 2018 08 23; 11(9). PMID: 29997220; PMCID: PMC6176993.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    35. Gritsenko PG, Friedl P. Adaptive adhesion systems mediate glioma cell invasion in complex environments. J Cell Sci. 2018 08 13; 131(15). PMID: 29991514; PMCID: PMC6104823.
      Citations: 13     Fields:    Translation:AnimalsCells
    36. Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P. Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone. Sci Transl Med. 2018 08 01; 10(452). PMID: 30068572; PMCID: PMC6326183.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    37. Odenthal J, Rijpkema M, Wagena E, Croes H, Grenman R, Boerman O, Takes R, Friedl P, Bos D. Targeting CD44v6 for fluorescence-guided surgery in head and neck squamous cell carcinoma. Sci Rep. 2018 Jul 11; 8(1):10467. PMID: 29992954; PMCID: PMC6041314.
      Citations: 12     Fields:    Translation:HumansAnimals
    38. Landgraf M, McGovern JA, Friedl P, Hutmacher DW. Rational Design of Mouse Models for Cancer Research. Trends Biotechnol. 2018 03; 36(3):242-251. PMID: 29310843.
      Citations: 22     Fields:    Translation:HumansAnimals
    39. van Helvert S, Storm C, Friedl P. Mechanoreciprocity in cell migration. Nat Cell Biol. 2018 01; 20(1):8-20. PMID: 29269951; PMCID: PMC5943039.
      Citations: 146     Fields:    Translation:HumansAnimalsCells
    40. Gritsenko P, Leenders W, Friedl P. Recapitulating in vivo-like plasticity of glioma cell invasion along blood vessels and in astrocyte-rich stroma. Histochem Cell Biol. 2017 Oct; 148(4):395-406. PMID: 28825130; PMCID: PMC5602046.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    41. Veelken C, Bakker GJ, Drell D, Friedl P. Single cell-based automated quantification of therapy responses of invasive cancer spheroids in organotypic 3D culture. Methods. 2017 09 01; 128:139-149. PMID: 28739118.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    42. Friedl P, Mayor R. Tuning Collective Cell Migration by Cell-Cell Junction Regulation. Cold Spring Harb Perspect Biol. 2017 Apr 03; 9(4). PMID: 28096261; PMCID: PMC5378050.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    43. Lehmann S, Te Boekhorst V, Odenthal J, Bianchi R, van Helvert S, Ikenberg K, Ilina O, Stoma S, Xandry J, Jiang L, Grenman R, Rudin M, Friedl P. Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells. Curr Biol. 2017 Feb 06; 27(3):392-400. PMID: 28089517.
      Citations: 45     Fields:    Translation:HumansCells
    44. Dondossola E, Holzapfel BM, Alexander S, Filippini S, Hutmacher DW, Friedl P. Examination of the foreign body response to biomaterials by nonlinear intravital microscopy. Nat Biomed Eng. 2016; 1. PMID: 28979821; PMCID: PMC5624536.
      Citations: 46     Fields:    
    45. Odenthal J, Takes R, Friedl P. Plasticity of tumor cell invasion: governance by growth factors and cytokines. Carcinogenesis. 2016 Dec; 37(12):1117-1128. PMID: 27664164.
      Citations: 33     Fields:    Translation:HumansCells
    46. Te Boekhorst V, Preziosi L, Friedl P. Plasticity of Cell Migration In Vivo and In Silico. Annu Rev Cell Dev Biol. 2016 10 06; 32:491-526. PMID: 27576118.
      Citations: 62     Fields:    Translation:HumansAnimals
    47. Te Boekhorst V, Friedl P. Plasticity of Cancer Cell Invasion-Mechanisms and Implications for Therapy. Adv Cancer Res. 2016; 132:209-64. PMID: 27613134.
      Citations: 28     Fields:    Translation:HumansAnimals
    48. Weigelin B, Friedl P. Cancer cells: Stemness shaped by curvature. Nat Mater. 2016 07 22; 15(8):827-8. PMID: 27443907.
      Citations:    Fields:    Translation:HumansCells
    49. van Helvert S, Friedl P. Strain Stiffening of Fibrillar Collagen during Individual and Collective Cell Migration Identified by AFM Nanoindentation. ACS Appl Mater Interfaces. 2016 Aug 31; 8(34):21946-55. PMID: 27128771.
      Citations: 53     Fields:    Translation:HumansCells
    50. Denais CM, Gilbert RM, Isermann P, McGregor AL, te Lindert M, Weigelin B, Davidson PM, Friedl P, Wolf K, Lammerding J. Nuclear envelope rupture and repair during cancer cell migration. Science. 2016 Apr 15; 352(6283):353-8. PMID: 27013428; PMCID: PMC4833568.
      Citations: 448     Fields:    Translation:HumansCells
    51. Weigelin B, Friedl P, Bola?os E, Rodriguez-Ruiz ME, Martinez-Forero I, Melero I. Anti-CD137 monoclonal antibodies and adoptive T cell therapy: a perfect marriage? Cancer Immunol Immunother. 2016 May; 65(5):493-7. PMID: 26970765.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    52. Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, Pirker C, Schmid JA, Loewe R, Wagner EF, Berger W, Petzelbauer P. Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma. J Invest Dermatol. 2016 05; 136(5):967-977. PMID: 26829032.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    53. Weigelin B, Bakker GJ, Friedl P. Third harmonic generation microscopy of cells and tissue organization. J Cell Sci. 2016 Jan 15; 129(2):245-55. PMID: 26743082.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    54. Haeger A, Wolf K, Zegers MM, Friedl P. Collective cell migration: guidance principles and hierarchies. Trends Cell Biol. 2015 Sep; 25(9):556-66. PMID: 26137890.
      Citations: 139     Fields:    Translation:HumansAnimalsCells
    55. Zegers MM, Friedl P. Translating Membrane Tension into Cytoskeletal Action by FBP17. Dev Cell. 2015 Jun 22; 33(6):628-30. PMID: 26102599.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    56. Weigelin B, Wagena E, Chen L, Friedl P, Bola?os E, Teijeira A, Martinez-Forero I, Labiano S, Azpilikueta A, Morales-Kastresana A, Quetglas JI, S?nchez-Paulete AR, Melero I. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proc Natl Acad Sci U S A. 2015 Jun 16; 112(24):7551-6. PMID: 26034288; PMCID: PMC4475992.
      Citations: 45     Fields:    Translation:AnimalsCells
    57. Chatterji T, Varkaris AS, Parikh NU, Song JH, Cheng CJ, Schweppe RE, Alexander S, Davis JW, Troncoso P, Friedl P, Kuang J, Lin SH, Gallick GE. Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells. Oncotarget. 2015 Apr 30; 6(12):10175-94. PMID: 25868388; PMCID: PMC4496348.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    58. Friedl P, Weigelin B. A Swiss Army knife for CTLs. Immunity. 2014 Dec 18; 41(6):873-5. PMID: 25526299.
      Citations: 1     Fields:    Translation:AnimalsCells
    59. Hoogenkamp HR, Bakker GJ, Wolf L, Suurs P, Dunnewind B, Barbut S, Friedl P, van Kuppevelt TH, Daamen WF. Directing collagen fibers using counter-rotating cone extrusion. Acta Biomater. 2015 Jan; 12:113-121. PMID: 25462525.
      Citations: 4     Fields:    Translation:Animals
    60. Zegers MM, Friedl P. Rho GTPases in collective cell migration. Small GTPases. 2014; 5:e28997. PMID: 25054920; PMCID: PMC4114924.
      Citations: 70     Fields:    Translation:Humans
    61. Haeger A, Krause M, Wolf K, Friedl P. Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement. Biochim Biophys Acta. 2014 Aug; 1840(8):2386-95. PMID: 24721714.
      Citations: 110     Fields:    Translation:HumansCells
    62. Friedl P, Wolf K, Zegers MM. Rho-directed forces in collective migration. Nat Cell Biol. 2014 Mar; 16(3):208-10. PMID: 24576897.
      Citations: 24     Fields:    Translation:Animals
    63. Alexander S, Friedl P, H?ger A. Cancer invasion and resistance. EJC Suppl. 2013 Sep; 11(2):291-3. PMID: 26217149; PMCID: PMC4041189.
      Citations: 5     
    64. Alexander S, Weigelin B, Winkler F, Friedl P. Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response. Curr Opin Cell Biol. 2013 Oct; 25(5):659-71. PMID: 23896198.
      Citations: 68     Fields:    Translation:HumansAnimals
    65. Maaser K, Wehrle-Haller B, Friedl P, Starke J. Mechanotransduction of mesenchymal melanoma cell invasion into 3D collagen lattices: filopod-mediated extension-relaxation cycles and force anisotropy. Exp Cell Res. 2013 Oct 01; 319(16):2424-33. PMID: 23830878.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    66. Wolf K, Te Lindert M, Krause M, Alexander S, Te Riet J, Willis AL, Hoffman RM, Figdor CG, Weiss SJ, Friedl P. Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J Cell Biol. 2013 Jun 24; 201(7):1069-84. PMID: 23798731; PMCID: PMC3691458.
      Citations: 507     Fields:    Translation:HumansAnimalsCells
    67. Friedl P, Sahai E, Weiss S, Yamada KM. New dimensions in cell migration. Nat Rev Mol Cell Biol. 2012 11; 13(11):743-7. PMID: 23072889.
      Citations: 94     Fields:    Translation:Cells
    68. Friedl P, Locker J, Sahai E, Segall JE. Classifying collective cancer cell invasion. Nat Cell Biol. 2012 Aug; 14(8):777-83. PMID: 22854810.
      Citations: 387     Fields:    Translation:HumansAnimals
    69. Weigelin B, Bakker GJ, Friedl P. Intravital third harmonic generation microscopy of collective melanoma cell invasion: Principles of interface guidance and microvesicle dynamics. Intravital. 2012; 1(1):32-43. PMID: 29607252; PMCID: PMC5858865.
      Citations: 124     
    70. Bonetto F, Srinivas M, Weigelin B, Cruz LJ, Heerschap A, Friedl P, Figdor CG, de Vries IJ. A large-scale (19)F MRI-based cell migration assay to optimize cell therapy. NMR Biomed. 2012 Sep; 25(9):1095-103. PMID: 22315137.
      Citations: 10     Fields:    Translation:HumansCells
    71. Friedl P, Hubbell J, Livingston D, Mihich E. Twenty-third annual Pezcoller Symposium: engineering influences in cancer research. Cancer Res. 2012 Feb 15; 72(4):841-4. PMID: 22237623.
      Citations:    Fields:    Translation:HumansAnimalsCells
    72. Bakker GJ, Andresen V, Hoffman RM, Friedl P. Fluorescence lifetime microscopy of tumor cell invasion, drug delivery, and cytotoxicity. Methods Enzymol. 2012; 504:109-25. PMID: 22264531.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    73. Gritsenko PG, Ilina O, Friedl P. Interstitial guidance of cancer invasion. J Pathol. 2012 Jan; 226(2):185-99. PMID: 22006671.
      Citations: 129     Fields:    Translation:HumansCells
    74. Alexander S, Friedl P. Cancer invasion and resistance: interconnected processes of disease progression and therapy failure. Trends Mol Med. 2012 Jan; 18(1):13-26. PMID: 22177734.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    75. Friedl P, Alexander S. Cancer invasion and the microenvironment: plasticity and reciprocity. Cell. 2011 Nov 23; 147(5):992-1009. PMID: 22118458.
      Citations: 822     Fields:    Translation:HumansAnimalsCells
    76. Wolf K, Friedl P. Extracellular matrix determinants of proteolytic and non-proteolytic cell migration. Trends Cell Biol. 2011 Dec; 21(12):736-44. PMID: 22036198.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    77. Friedl PG, Rappold EM, J?ger C. Effective and minimally painful surgery of pilonidal sinus - asymmetric transposition flap according to Dufourmentel. J Dtsch Dermatol Ges. 2011 Apr; 9(4):333-5. PMID: 21371259.
      Citations: 2     Fields:    Translation:Humans
    78. Weigelin B, Krause M, Friedl P. Cytotoxic T lymphocyte migration and effector function in the tumor microenvironment. Immunol Lett. 2011 Jul; 138(1):19-21. PMID: 21333682.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    79. Ilina O, Bakker GJ, Vasaturo A, Hofmann RM, Friedl P. Two-photon laser-generated microtracks in 3D collagen lattices: principles of MMP-dependent and -independent collective cancer cell invasion. Phys Biol. 2011 Feb; 8(1):015010. PMID: 21301056.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    80. Dommerholt J, Schmidt S, Temming R, Hendriks LJ, Rutjes FP, van Hest JC, Lefeber DJ, Friedl P, van Delft FL. Readily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells. Angew Chem Int Ed Engl. 2010 Dec 03; 49(49):9422-5. PMID: 20857472; PMCID: PMC3021724.
      Citations: 137     Fields:    Translation:HumansCells
    81. Friedl P, Wolf K, Lammerding J. Nuclear mechanics during cell migration. Curr Opin Cell Biol. 2011 Feb; 23(1):55-64. PMID: 21109415; PMCID: PMC3073574.
      Citations: 202     Fields:    Translation:Cells
    82. Friedl P, Khalil AA. Determinants of leader cells in collective cell migration. Integr Biol (Camb). 2010 Nov; 2(11-12):568-74. PMID: 20886167.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    83. Weigelin B, Friedl P. A three-dimensional organotypic assay to measure target cell killing by cytotoxic T lymphocytes. Biochem Pharmacol. 2010 Dec 15; 80(12):2087-91. PMID: 20849829.
      Citations: 6     Fields:    Translation:AnimalsCells
    84. Friedl P, Zallen JA. Dynamics of cell-cell and cell-matrix interactions in morphogenesis, regeneration and cancer. Curr Opin Cell Biol. 2010 Oct; 22(5):557-9. PMID: 20850290.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    85. Friedl P. To adhere or not to adhere? Nat Rev Mol Cell Biol. 2010 Jan; 11(1):3. PMID: 20050305.
      Citations: 5     Fields:    Translation:HumansAnimals
    86. Friedl P, Wolf K. Plasticity of cell migration: a multiscale tuning model. J Cell Biol. 2010 Jan 11; 188(1):11-9. PMID: 19951899; PMCID: PMC2812848.
      Citations: 548     Fields:    Translation:HumansAnimalsCells
    87. Schmidt S, Friedl P. Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms. Cell Tissue Res. 2010 Jan; 339(1):83-92. PMID: 19921267; PMCID: PMC2784868.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    88. Ilina O, Friedl P. Mechanisms of collective cell migration at a glance. J Cell Sci. 2009 Sep 15; 122(Pt 18):3203-8. PMID: 19726629.
      Citations: 123     Fields:    Translation:HumansAnimals
    89. Wolf K, Alexander S, Schacht V, Coussens LM, von Andrian UH, van Rheenen J, Deryugina E, Friedl P. Collagen-based cell migration models in vitro and in vivo. Semin Cell Dev Biol. 2009 Oct; 20(8):931-41. PMID: 19682592; PMCID: PMC4021709.
      Citations: 257     Fields:    Translation:HumansAnimalsCells
    90. Berton S, Belletti B, Wolf K, Canzonieri V, Lovat F, Vecchione A, Colombatti A, Friedl P, Baldassarre G. The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition. Mol Cell Biol. 2009 Sep; 29(18):5031-45. PMID: 19596789; PMCID: PMC2738297.
      Citations: 40     Fields:    Translation:AnimalsCells
    91. Polzer B, Alexander S, Klein CA, Friedl P, Imle A. Genomic instability of micronucleated cells revealed by single-cell comparative genomic hybridization. Cytometry A. 2009 Jul; 75(7):562-8. PMID: 19405114.
      Citations: 8     Fields:    Translation:HumansCells
    92. Friedl P, Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol. 2009 Jul; 10(7):445-57. PMID: 19546857.
      Citations: 943     Fields:    Translation:HumansAnimals
    93. Friedl P, Wolf K. Proteolytic interstitial cell migration: a five-step process. Cancer Metastasis Rev. 2009 Jun; 28(1-2):129-35. PMID: 19153672.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    94. Alexander S, Heupel WM, Hirschberg M, Hoffman RM, Friedl P, Andresen V. Infrared multiphoton microscopy: subcellular-resolved deep tissue imaging. Curr Opin Biotechnol. 2009 Feb; 20(1):54-62. PMID: 19324541.
      Citations: 68     Fields:    Translation:Animals
    95. Friedl P. Dynamic imaging of cancer invasion and metastasis: principles and preclinical applications. Clin Exp Metastasis. 2009; 26(4):269-71. PMID: 19229643.
      Citations: 1     Fields:    Translation:HumansAnimals
    96. Koehl GE, Hirschberg M, Geissler EK, Friedl P, Alexander S. Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model. Histochem Cell Biol. 2008 Dec; 130(6):1147-54. PMID: 18987875.
      Citations: 121     Fields:    Translation:HumansAnimalsCells
    97. Friedl P, Weigelin B. Interstitial leukocyte migration and immune function. Nat Immunol. 2008 Sep; 9(9):960-9. PMID: 18711433.
      Citations: 225     Fields:    Translation:HumansAnimalsCells
    98. Wolf K, Friedl P. Mapping proteolytic cancer cell-extracellular matrix interfaces. Clin Exp Metastasis. 2009; 26(4):289-98. PMID: 18600304.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    99. Belletti B, Nicoloso MS, Schiappacassi M, Berton S, Lovat F, Wolf K, Canzonieri V, D'Andrea S, Zucchetto A, Friedl P, Colombatti A, Baldassarre G. Stathmin activity influences sarcoma cell shape, motility, and metastatic potential. Mol Biol Cell. 2008 May; 19(5):2003-13. PMID: 18305103; PMCID: PMC2366875.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    100. Wu YI, Liu Y, Tam E, Overall C, Stack MS, Friedl P, Wolf K, Geiger J. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol. 2007 Aug; 9(8):893-904. PMID: 17618273.
      Citations: 445     Fields:    Translation:HumansAnimalsCells
    101. Wolf K, von Andrian UH, Harms G, Friedl P. Biological second and third harmonic generation microscopy. Curr Protoc Cell Biol. 2007 Mar; Chapter 4:Unit 4.15. PMID: 18228516.
      Citations: 30     Fields:    Translation:AnimalsCells
    102. Friedl P, Wolf K. Molecular mechanisms of cancer cell invasion and plasticity. Br J Dermatol. 2006 May; 154 Suppl 1:11-5. PMID: 16712711.
      Citations: 68     Fields:    Translation:HumansCells
    103. Friedl P. Cell fusion: new mechanisms of plasticity in cancer? Lancet Oncol. 2005 Dec; 6(12):916-8. PMID: 16321755.
      Citations: 6     Fields:    Translation:Humans
    104. Wolf K, Friedl P. Functional imaging of pericellular proteolysis in cancer cell invasion. Biochimie. 2005 Mar-Apr; 87(3-4):315-20. PMID: 15781318.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    105. Maaser K, Daryab N, Friedl P, Mayer C, Z?nker KS, Br?cker EB. Release of cell fragments by invading melanoma cells. Eur J Cell Biol. 2004 Dec; 83(11-12):709-15. PMID: 15679115.
      Citations: 14     Fields:    Translation:HumansCells
    106. Uhlenbrock K, Eberth A, Herbrand U, Daryab N, Stege P, Meier F, Friedl P, Collard JG, Ahmadian MR. The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism. J Cell Sci. 2004 Sep 15; 117(Pt 20):4863-71. PMID: 15340013.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    107. Friedl P. Prespecification and plasticity: shifting mechanisms of cell migration. Curr Opin Cell Biol. 2004 Feb; 16(1):14-23. PMID: 15037300.
      Citations: 244     Fields:    Translation:AnimalsCells
    108. Hegerfeldt Y, Tusch M, Friedl P. Collective cell migration in morphogenesis and cancer. Int J Dev Biol. 2004; 48(5-6):441-9. PMID: 15349818.
      Citations: 146     Fields:    Translation:HumansAnimals
    109. Wolf K, Friedl P. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer. 2003 May; 3(5):362-74. PMID: 12724734.
      Citations: 1226     Fields:    Translation:HumansAnimals
    110. Mazo I, Leung H, Engelke K, von Andrian UH, Deryugina EI, Strongin AY, Friedl P, Wolf K, Br?cker EB. Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol. 2003 Jan 20; 160(2):267-77. PMID: 12527751; PMCID: PMC2172637.
      Citations: 584     Fields:    Translation:HumansAnimalsCells
    111. Tusch M, Friedl P, Hegerfeldt Y, Br?cker EB. Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies. Cancer Res. 2002 Apr 01; 62(7):2125-30. PMID: 11929834.
      Citations: 142     Fields:    Translation:Humans
    112. Borgmann S, Grabbe S, Friedl P, Gunzer M, Sch?fer A, Z?nker KS, Br?cker EB, K?mpgen E. Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. Immunity. 2000 Sep; 13(3):323-32. PMID: 11021530.
      Citations: 128     Fields:    Translation:HumansAnimalsCells
    113. Friedl P, Br?cker EB. The biology of cell locomotion within three-dimensional extracellular matrix. Cell Mol Life Sci. 2000 Jan 20; 57(1):41-64. PMID: 10949580.
      Citations: 199     Fields:    Translation:HumansAnimalsCells
    114. Entschladen F, Niggemann B, Friedl P, Z?nker KS. Differential requirement of protein tyrosine kinases and protein kinase C in the regulation of T cell locomotion in three-dimensional collagen matrices. J Immunol. 1997 Oct 01; 159(7):3203-10. PMID: 9317118.
      Citations: 11     Fields:    Translation:HumansCells
    115. Tissue source and maturation state determine the spontaneous and cytokine driven migration pattern of murine dendritic cells and Langerhans cells within a 3-D collagen lattice. Immunobiology. 197:304-305.
    116. Plasticity of Cell Migration in Vivo and in Silico. Annual Review of Cell and Developmental Biology. 32:491-526.
    117. Strain Stiffening of Fibrillar Collagen during Individual and Collective Cell Migration Identified by AFM Nanoindentation. ACS Applied Materials and Interfaces. 8:21946-21955.
    118. Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells. Current Biology.
    119. Cancer invasion and resistance. European Journal of Cancer, Supplement. 11:291-293.
    120. Infrared multiphoton microscopy beyond 1 micon.
    121. Nuclear envelope rupture and repair during cancer cell migration. Science. 352:353-358.
    122. Infrared multiphoton microscopy beyond 1 micron.
    123. Leukocytes (T lymphocytes, dendritic cells, monocytes) utilize β1 integrin independent migration strategies for polarization, interaction with collagen fibers and migration. Immunobiology. 197:303-304.
    124. Locomotion of human T lymphocytes in 3-D collagen lattices in vitro -adhesion requirements and redistribution of β1 integrins. FASEB Journal. 10.
    125. Corrigendum to " Nuclear mechanics during cell migration" [Curr. Opin. Cell Biol. 23 (2011) 55-64]. Current Opinion in Cell Biology. 23:253.
    126. Plasticity of Cancer Cell Invasion-Mechanisms and Implications for Therapy. Advances in Cancer Research.
    127. Cancer cells. Nature Materials. 15:827-828.
    128. Divergent migratory properties and phenotypes emerging from in vitro generated human dendritic cells upon culture in three dimensional collagen lattices. Immunobiology. 197:303.
    129. Infrared multiphoton microscopy beyond 1 micron.
    130. Erratum. Journal of Leukocyte Biology. 71:377.
    131. Infrared multiphoton microscopy beyond 1 micron.
    132. Erratum. Nature Cell Biology. 16:383.
    133. Third harmonic generation microscopy of cells and tissue organization. Journal of Cell Science. 129:245-255.
    134. Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells. Oncotarget. 6:10175-10194.
    135. Erratum. Physical Biology. 8.
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