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NAVAL DAVER
Title
Assistant Professor
Institution
MD Anderson
Department
Leukemia
Address
1400 Holcombe Blvd
Houston TX 77030-4008
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Zeidan AM, Platzbecker U, Bewersdorf JP, Stahl M, Ad?s L, Borate U, Bowen DT, Buckstein RJ, Brunner AM, Carraway HE, Daver NG, D?ez-Campelo M, de Witte TM, DeZern AE, Efficace F, Garcia-Manero G, Garcia JS, Germing U, Giagounidis A, Griffiths EA, Hasserjian RP, Hellstr?m-Lindberg E, Iastrebner MC, Komrokji RS, Kulasekararaj AG, Malcovati L, Miyazaki Y, Odenike O, Santini V, Sanz GF, Scheinberg P, Stauder R, Van de Loosdrecht AA, Wei AH, Sekeres MA, Fenaux P, Zeidan AM, Platzbecker U, Bewersdorf JP, Stahl M, Ad?s L, Borate U, Bowen D, Buckstein R, Brunner A, Carraway HE,
Daver N
, D?ez-Campelo M, de Witte T, DeZern AE, Efficace F,
Garcia-Manero G
, Garcia JS, Germing U, Giagounidis A, Griffiths EA, Hasserjian RP, Hellstr?m-Lindberg E, Iastrebner M, Komrokji R, Kulasekararaj AG, Malcovati L, Miyazaki Y, Odenike O, Santini V, Sanz G, Scheinberg P, Stauder R, van de Loosdrecht AA, Wei AH, Sekeres MA, Fenaux P. Consensus proposal for revised International Working Group 2023 response criteria for higher-risk myelodysplastic syndromes. Blood. 2023 Apr 27; 141(17):2047-2061.
PMID:
36724453
.
Citations:
Fields:
Hem
Hematology
Lachowiez CA,
Loghavi S
, Zeng Z, Tanaka T, Kim YJ, Uryu H, Turkalj S, Jakobsen NA, Luskin MR, Duose DY, Tidwell RSS, Short NJ,
Borthakur G
,
Kadia TM
, Masarova L, Tippett GD,
Bose P
, Jabbour EJ, Ravandi F,
Daver NG
,
Garcia-Manero G
,
Kantarjian H
, Garcia JS, Vyas P,
Takahashi K
,
Konopleva M
,
DiNardo CD
. A phase Ib/II study of ivosidenib with venetoclax +/- azacitidine in IDH1-mutated myeloid malignancies. Blood Cancer Discov. 2023 Apr 27.
PMID:
37102976
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Short NJ, Ong F, Ravandi F, Nogueras Gonzalez GM,
Kadia TM
,
Daver NG
,
DiNardo CD
,
Konopleva MY
,
Borthakur G
,
Oran B
,
Al-Atrash G
,
Mehta RS
,
Jabbour EJ
, Yilmaz M, Issa GC, Maiti A,
Champlin RE
,
Kantarjian HM
,
Shpall EJ
,
Popat UR
. Impact of Type of Induction Therapy on Outcomes in Older Adults with AML after Allogeneic Stem Cell Transplantation. Blood Adv. 2023 Apr 27.
PMID:
37104058
.
Citations:
Fields:
Hem
Hematology
Jia Y, Han L, Ramage CL, Wang Z, Weng CC, Yang L,
Colla S
, Ma H, Zhang W,
Andreeff M
,
Daver N
,
Jain N
,
Pemmaraju N
,
Bhalla K
, Mustjoki S, Zhang P, Zheng G, Zhou D, Zhang Q,
Konopleva M
. Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells. Haematologica. 2023 Apr 20.
PMID:
37078252
.
Citations:
Fields:
Hem
Hematology
Fiskus W
, Mill CP, Birdwell C, Davis JA, Das K, Boettcher S,
Kadia TM
,
DiNardo CD
,
Takahashi K
,
Loghavi S
, Soth MJ, Heffernan T, McGeehan GM, Ruan X,
Su X
, Vakoc CR,
Daver N
,
Bhalla KN
. Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1. Blood Cancer J. 2023 04 13; 13(1):53.
PMID:
37055414
; PMCID:
PMC10102188
.
Citations:
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Lee SE, Wang F, Grefe M, Trujillo-Ocampo A, Ruiz-Vasquez W,
Takahashi K
, Abbas HA, Borges P, Antunes DA,
Al-Atrash G
,
Daver N
,
Molldrem JJ
,
Futreal A
,
Garcia-Manero G
, Im JS. Immunologic Predictors for Clinical Responses during Immune Checkpoint Blockade in Patients with Myelodysplastic Syndromes. Clin Cancer Res. 2023 Mar 29; OF1-OF14.
PMID:
36988276
.
Citations:
Fields:
Neo
Neoplasms
Mill CP,
Fiskus W
, Das K, Davis JA, Birdwell CE,
Kadia TM
,
DiNardo CD
,
Daver N
,
Takahashi K
, Sasaki K, McGeehan GM, Ruan X, Su X,
Loghavi S
,
Kantarjian H
,
Bhalla KN
. Causal linkage of presence of mutant NPM1 to efficacy of novel therapeutic agents against AML cells with mutant NPM1. Leukemia. 2023 Mar 28.
PMID:
36977823
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Issa GC, Bidikian A, Venugopal S,
Konopleva M
,
DiNardo CD
,
Kadia TM
,
Borthakur G
,
Jabbour E
,
Pemmaraju N
, Yilmaz M, Short NJ, Maiti A, Sasaki K, Masarova L, Pierce S,
Takahashi K
, Tang G,
Loghavi S
,
Patel K
,
Andreeff M
,
Bhalla K
,
Garcia-Manero G
, Ravandi F,
Kantarjian H
,
Daver N
. Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML. Blood Adv. 2023 03 28; 7(6):933-942.
PMID:
36322818
; PMCID:
PMC10027507
.
Citations:
Trabal A, Gibson A, He J, McCall D, Roth M, Nu?ez C, Garcia M, Buzbee M, Toepfer L, Bidikian A,
Daver N
,
Kadia T
, Short NJ, Issa GC, Ravandi F,
DiNardo CD
, Montalban Bravo G, Garces S,
Marcogliese A
,
Paek H
, Dreyer Z,
Brackett J
,
Redell M
,
Yi J
,
Garcia-Manero G
,
Konopleva M
, Stevens A, Cuglievan B. Venetoclax for Acute Myeloid Leukemia in Pediatric Patients: A Texas Medical Center Experience. Cancers (Basel). 2023 Mar 26; 15(7).
PMID:
37046645
; PMCID:
PMC10093646
.
Citations:
Richard-Carpentier G, Rausch CR, Sasaki K, Hammond D, Morita K,
Takahashi K
, Tang G, Kanagal-Shamanna R,
Bhalla K
,
Dinardo CD
,
Borthakur G
,
Pemmaraju N
,
Shpall EJ
,
Alousi A
,
Daver NG
,
Garcia-Manero G
,
Konopleva MY
, Ravandi F,
Kantarjian HM
,
Kadia TM
. Characteristics and clinical outcomes of patients with acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2). Haematologica. 2023 Mar 23.
PMID:
36951163
.
Citations:
Fields:
Hem
Hematology
Daver NG
, Dail M, Garcia JS, Jonas BA, Yee KWL, Kelly KR, Vey N, Assouline S, Roboz GJ, Paolini S, Pollyea DA, Tafuri A, Brandwein JM, Pigneux A, Powell BL, Fenaux P, Olin RL, Visani G, Martinelli G, Onishi M, Wang J, Huang W, Green C, Ott MG, Hong WJ,
Konopleva MY
,
Andreeff M
. Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial. Blood. 2023 03 16; 141(11):1265-1276.
PMID:
36265087
.
Citations:
Abbas HA, Sun H, Pierce S, Kanagal-Shamanna R, Li Z, Yilmaz M,
Borthakur G
, DiPippo AJ,
Jabbour E
,
Konopleva M
, Short NJ,
DiNardo C
,
Daver N
, Ravandi F,
Kadia TM
. Validation of the ALFA-1200 model in older patients with AML treated with intensive chemotherapy. Blood Adv. 2023 03 14; 7(5):828-831.
PMID:
35405739
; PMCID:
PMC9996355
.
Citations:
Fields:
Hem
Hematology
Bewersdorf JP, Xie Z, Bejar R, Borate U, Boultwood J, Brunner AM, Buckstein R, Carraway HE, Churpek JE,
Daver NG
, Porta MGD, DeZern AE, Fenaux P, Figueroa ME, Gore SD, Griffiths EA, Halene S, Hasserjian RP, Hourigan CS, Kim TK, Komrokji R, Kuchroo VK, List AF,
Loghavi S
, Majeti R, Odenike O, Patnaik MM, Platzbecker U, Roboz GJ, Sallman DA, Santini V, Sanz G, Sekeres MA, Stahl M, Starczynowski DT, Steensma DP, Taylor J, Abdel-Wahab O, Xu ML, Savona MR, Wei AH, Zeidan AM. Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1st International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS). Blood Rev. 2023 Mar 11; 101072.
PMID:
36934059
.
Citations:
Fields:
Hem
Hematology
Nguyen D,
Kantarjian HM
, Short NJ, Qiao W, Ning J, Cuglievan B,
Daver NG
,
DiNardo CD
,
Jabbour EJ
,
Kadia TM
,
Borthakur G
,
Garcia-Manero G
,
Konopleva MY
,
Andreeff M
,
Ravandi-Kashani F
, Sasaki K, Issa GC. Early mortality in acute myeloid leukemia with KMT2A rearrangement is associated with high risk of bleeding and disseminated intravascular coagulation. Cancer. 2023 Mar 09.
PMID:
36892949
.
Citations:
Fields:
Neo
Neoplasms
Bazinet A,
Kadia TM
, Short NJ,
Borthakur G
, Wang SA, Wang W,
Loghavi S
,
Jorgensen JL
,
Patel KP
,
DiNardo CD
,
Daver NG
,
Alvarado Y
, Haddad FG, Pierce SR, Nogueras Gonzalez GM, Maiti A, Sasaki K, Yilmaz M, Thompson PA,
Wierda WG
,
Garcia-Manero G
,
Andreeff M
,
Jabbour EJ
,
Konopleva MY
, Huang X,
Kantarjian HM
, Ravandi F. Undetectable Measurable Residual Disease is Associated with Improved Outcomes in AML Irrespective of Treatment Intensity. Blood Adv. 2023 Mar 08.
PMID:
36884300
.
Citations:
Fields:
Hem
Hematology
Sallman DA, Al Malki MM, Asch AS, Wang ES, Jurcic JG, Bradley TJ, Flinn IW, Pollyea DA, Kambhampati S, Tanaka TN, Zeidner JF,
Garcia-Manero G
, Jeyakumar D, Komrokji R, Lancet J,
Kantarjian HM
, Gu L, Zhang Y, Tan A, Chao M, O'Hear C, Ramsingh G, Lal I, Vyas P,
Daver NG
. Magrolimab in Combination With Azacitidine in Patients With Higher-Risk Myelodysplastic Syndromes: Final Results of a Phase Ib Study. J Clin Oncol. 2023 Mar 08; JCO2201794.
PMID:
36888930
.
Citations:
Fields:
Neo
Neoplasms
Daver NG
, Iqbal S, Renard C, Chan RJ, Hasegawa K, Hu H, Tse P, Yan J, Zoratti MJ, Xie F, Ramsingh G. Treatment outcomes for newly diagnosed, treatment-na?ve TP53-mutated acute myeloid leukemia: a systematic review and meta-analysis. J Hematol Oncol. 2023 03 06; 16(1):19.
PMID:
36879351
; PMCID:
PMC9990239
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Rios M, Morse JW, Ye J, Rios A, Zhang CC,
Daver NG
,
DiNardo CD
, Zhang N, An Z. Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets. Expert Opin Investig Drugs. 2023 Feb; 32(2):107-125.
PMID:
36762937
; PMCID:
PMC10031751
.
Citations:
Fields:
Dru
Drug Therapy
Translation:
Humans
Konopleva M
,
DiNardo C
, Bhagat T, Baran N, Lodi A, Saxena K, Cai T, Su X, Skwarska A, Guerra V, Kuruvilla V, Konoplev S, Gordon-Mitchell S, Pradhan K, Aluri S, Collins M, Sweeney S, Busquet J, Rathore A, Deng Q, Green M, Grant S, Demo S, Choudhary G, Sahu S, Agarwal B, Spodek M, Thiruthuvanathan V, Will B, Steidl U, Tippett G, Burger J,
Borthakur G
,
Jabbour E
,
Pemmaraju N
,
Kadia T
,
Kornblau S
,
Daver N
,
Naqvi K
, Short N,
Garcia-Manero G
, Tiziani S, Verma A. Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses. Res Sq. 2023 Feb 23.
PMID:
36865338
; PMCID:
PMC9980221
.
Citations:
Pemmaraju N
,
Kantarjian H
, Sweet K, Wang E, Senapati J, Wilson NR,
Konopleva M
, Frankel AE, Gupta V, Mesa R, Ulrickson M, Gorak E, Bhatia S, Budak-Alpdogan T, Mason J, Garcia-Romero MT, Lopez-Santiago N, Cesarman-Maus G, Vachhani P, Lee S, Bhatt VR, Blum W, Walter RB, Bixby D, Gojo I,
Duvic M
, Rampal RK, de Lima M, Foran J, Fathi AT, Hall AC, Jacoby MA, Lancet J, Mannis G, Stein AS, Mims A, Rizzieri D, Olin R, Perl A, Schiller G, Shami P, Stone RM, Strickland S, Wieduwilt MJ,
Daver N
, Ravandi F, Vasu S, Guzman M, Roboz GJ,
Khoury J
,
Qazilbash M
,
Aung PP
, Cuglievan B, Madanat Y, Kharfan-Dabaja MA, Pawlowska A, Taylor J, Tallman M, Dhakal P, Lane AA. North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need. Blood. 2023 02 09; 141(6):567-578.
PMID:
36399715
.
Citations:
Siddiqui M,
Konoplev S
, Issa G,
Kantarjian H
,
Daver N
, Ravandi F,
Kadia T
, Tang G, Wang SA,
Thakral B
,
Medeiros LJ
, Pozdnyakova O, Pierce S, Montalban-Bravo G, Chien K, Hammond D, Sasaki K,
Garcia-Manero G
, Hasserjian RP. Biologic features and clinical outcomes in newly diagnosed myelodysplastic syndrome with KMT2A rearrangements. Am J Hematol. 2023 Apr; 98(4):E91-E94.
PMID:
36661399
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Sasaki K, Ravandi F,
Kadia TM
,
Borthakur G
, Short NJ,
Jain N
,
Daver NG
,
Jabbour EJ
,
Garcia-Manero G
,
Loghavi S
,
Patel KP
, Montalban-Bravo G, Masarova L,
DiNardo CD
,
Kantarjian HM
. Prediction of survival with lower intensity therapy among older patients with acute myeloid leukemia. Cancer. 2023 04 01; 129(7):1017-1029.
PMID:
36715486
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Yap TA,
Daver N
, Mahendra M, Zhang J, Kamiya-Matsuoka C,
Meric-Bernstam F
,
Kantarjian HM
, Ravandi F, Collins ME, Francesco MED, Dumbrava EE,
Fu S
, Gao S, Gay JP, Gera S, Han J,
Hong DS
,
Jabbour EJ
, Ju Z,
Karp DD
, Lodi A, Molina JR, Baran N,
Naing A
,
Ohanian M
,
Pant S
,
Pemmaraju N
,
Bose P
,
Piha-Paul SA
, Rodon J, Salguero C, Sasaki K, Singh AK,
Subbiah V
,
Tsimberidou AM
, Xu QA, Yilmaz M, Zhang Q, Li Y, Bristow CA, Bhattacharjee MB, Tiziani S, Heffernan TP, Vellano CP, Jones P,
Heijnen CJ
,
Kavelaars A
, Marszalek JR,
Konopleva M
. Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nat Med. 2023 01; 29(1):115-126.
PMID:
36658425
.
Citations:
5
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Animals
Cells
CT
Clinical Trials
Aminu M, Yadav D, Hong L, Young E, Edelkamp P, Saad M, Salehjahromi M, Chen P, Sujit SJ, Chen MM,
Sabloff B
,
Gladish G
,
de Groot PM
,
Godoy MCB
, Cascone T, Vokes NI, Zhang J, Brock KK,
Daver N
,
Woodman SE
,
Tawbi HA
,
Sheshadri A
, Lee JJ, Jaffray D,
Wu CC
,
Chung C
, Wu J. Habitat Imaging Biomarkers for Diagnosis and Prognosis in Cancer Patients Infected with COVID-19. Cancers (Basel). 2022 Dec 31; 15(1).
PMID:
36612278
.
Citations:
Senapati J, Abuasab T, Haddad FG, Ravandi F,
Kadia T
,
DiNardo C
,
Daver N
,
Pemmaraju N
,
Alvarado Y
, Brandt MA,
Kantarjian H
,
Borthakur G
. Common kinase mutations do not impact optimal molecular responses in core binding factor acute myeloid leukemia treated with fludarabine, cytarabine, and G-CSF based regimens. Am J Hematol. 2023 03; 98(3):E53-E56.
PMID:
36565294
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Zeng Z
, Maiti A, Herbrich S, Cai T, Cavazos A, Manzella T, Ma H, Hayes K, Matthews J,
DiNardo CD
,
Daver NG
,
Konopleva MY
. Triple combination targeting methyltransferase, BCL-2, and PD-1 facilitates antileukemia responses in acute myeloid leukemia. Cancer. 2023 02 15; 129(4):531-540.
PMID:
36477735
.
Citations:
Bazinet A, Darbaniyan F,
Kadia TM
, Venugopal S, Kanagal-Shamanna R,
DiNardo CD
,
Borthakur G
,
Jabbour EJ
,
Daver NG
,
Pemmaraju N
,
Konopleva MY
, Ravandi F, Sasaki K, Chien KS, Hammond D, Pierce SA,
Kantarjian HM
,
Garcia-Manero G
, Montalban-Bravo G. A retrospective study of cladribine and low-dose cytarabine-based regimens for the treatment of chronic myelomonocytic leukemia and secondary acute myeloid leukemia. Cancer. 2023 02 15; 129(4):560-568.
PMID:
36458426
.
Citations:
Shallis RM,
Daver NG
, Altman JK, Hasserjian RP,
Kantarjian HM
, Platzbecker U, Santini V, Wei AH, Sallman DA, Zeidan AM. TP53-altered acute myeloid leukemia and myelodysplastic syndrome with excess blasts should be approached as a single entity. Cancer. 2023 01 15; 129(2):175-180.
PMID:
36397669
.
Citations:
Jabbour E
, Short NJ,
Jain N
, Huang X, Montalban-Bravo G, Banerjee P, Rezvani K, Jiang X, Kim KH, Kanagal-Shamanna R,
Khoury JD
, Patel K,
Kadia TM
,
Daver N
, Chien K,
Alvarado Y
,
Garcia-Manero G
, Issa GC, Haddad FG, Kwari M, Thankachan J, Delumpa R, Macaron W, Garris R,
Konopleva M
, Ravandi F,
Kantarjian H
. Ponatinib and blinatumomab for Philadelphia chromosome-positive acute lymphoblastic leukaemia: a US, single-centre, single-arm, phase 2 trial. Lancet Haematol. 2022 Nov 16.
PMID:
36402146
.
Citations:
Hasegawa K, Wei AH,
Garcia-Manero G
,
Daver NG
, Rajakumaraswamy N, Iqbal S, Chan RJ, Hu H, Tse P, Yan J, Zoratti MJ, Xie F, Sallman DA. Azacitidine Monotherapy in Patients With Treatment-Na?ve Higher-risk Myelodysplastic Syndrome: A Systematic Literature Review and Meta-analysis. Clin Lymphoma Myeloma Leuk. 2023 02; 23(2):127-137.
PMID:
36428152
.
Citations:
Daver NG
, Maiti A,
Kadia TM
, Vyas P, Majeti R, Wei AH,
Garcia-Manero G
, Craddock C, Sallman DA,
Kantarjian HM
. TP53-Mutated Myelodysplastic Syndrome and Acute Myeloid Leukemia: Biology, Current Therapy, and Future Directions. Cancer Discov. 2022 Nov 02; 12(11):2516-2529.
PMID:
36218325
; PMCID:
PMC9627130
.
Citations:
Senapati J,
Daver NG
,
Pemmaraju N
. Antibody-Drug Conjugates in Myeloid Leukemias. Cancer J. 2022 Nov-Dec 01; 28(6):454-461.
PMID:
36383908
.
Citations:
Jain N
, Senapati J,
Thakral B
,
Ferrajoli A
, Thompson PA,
Burger JA
, Basu S,
Kadia TM
,
Daver NG
,
Borthakur G
,
Konopleva M
,
Pemmaraju N
, Parry EM, Wu CJ,
Khoury JD
,
Bueso-Ramos CE
,
Garg N
, Wang X, Lopez W, Ayala A, O'Brien SM,
Kantarjian HM
, Keating MJ,
Allison JP
,
Sharma P
,
Wierda WG
. A Phase 2 Study of Nivolumab Combined with Ibrutinib in Patients with Diffuse Large B-cell Richter Transformation of CLL. Blood Adv. 2022 Oct 26.
PMID:
36287248
.
Citations:
Zeidan AM, Bewersdorf JP, Buckstein R, Sekeres MA, Steensma DP, Platzbecker U,
Loghavi S
, Boultwood J, Bejar R, Bennett JM, Borate U, Brunner AM, Carraway H, Churpek JE,
Daver NG
, Della Porta M, DeZern AE, Efficace F, Fenaux P, Figueroa ME, Greenberg P, Griffiths EA, Halene S, Hasserjian RP, Hourigan CS, Kim N, Kim TK, Komrokji RS, Kutchroo V, List AF, Little RF, Majeti R, Nazha A, Nimer SD, Odenike O, Padron E, Patnaik MM, Roboz GJ, Sallman DA, Sanz G, Stahl M, Starczynowski DT, Taylor J, Xie Z, Xu M, Savona MR, Wei AH, Abdel-Wahab O, Santini V. Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes. Leukemia. 2022 Dec; 36(12):2939-2946.
PMID:
36266326
.
Citations:
Sperling AS, Guerra VA, Kennedy JA, Yan Y, Hsu JI, Wang F, Nguyen AT, Miller PG, McConkey ME, Quevedo Barrios VA, Furudate K, Zhang L, Kanagal-Shamanna R, Zhang J, Little L, Gumbs C,
Daver N
,
DiNardo CD
,
Kadia T
, Ravandi F,
Kantarjian H
,
Garcia-Manero G
,
Futreal PA
, Ebert BL,
Takahashi K
. Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms. Blood. 2022 10 20; 140(16):1753-1763.
PMID:
35512188
.
Citations:
Fields:
Hem
Hematology
Stahl M, Abdel-Wahab O, Wei AH, Savona MR, Xu ML, Xie Z, Taylor J, Starczynowski DT, Sanz GF, Sallman DA, Santini V, Roboz GJ, Patnaik MM, Padron E, Odenike O, Nazha A, Nimer SD, Majeti R, Little RF, Gore SD, List AF, Kuchroo V, Komrokji RS, Kim TK, Kim N, Hourigan CS, Hasserjian RP, Halene S, Griffiths EA, Greenberg PL, Figueroa ME, Fenaux P, Efficace F, DeZern AE, Della Porta MG,
Daver NG
, Churpek JE, Carraway HE, Brunner AM, Borate U, Bennett JM, Bejar R, Boultwood J,
Loghavi S
, Bewersdorf JP, Platzbecker U, Steensma DP, Sekeres MA, Buckstein RJ, Zeidan AM. An agenda to advance research in MDS: A TOP 10 Priority List from the first international workshop in MDS (iwMDS). Blood Adv. 2022 Oct 19.
PMID:
36260702
.
Citations:
Rivera D, Kim K, Kanagal-Shamanna R,
Borthakur G
, Montalban-Bravo G,
Daver N
,
Dinardo C
, Short NJ, Yilmaz M,
Pemmaraju N
,
Takahashi K
,
Jabbour EJ
, Pierce S,
Konopleva M
,
Bhalla K
,
Garcia-Manero G
, Ravandi F,
Kantarjian H
,
Kadia TM
. Implications of RAS mutational status in subsets of patients with newly diagnosed acute myeloid leukemia across therapy subtypes. Am J Hematol. 2022 Dec; 97(12):1599-1606.
PMID:
36117258
.
Citations:
Venugopal S,
Borthakur G
,
Daver N
,
DiNardo CD
,
Pemmaraju N
, Short NJ, Abbas HA,
Garcia-Manero G
,
Konopleva M
, Ravandi F,
Kadia TM
. Validation of ALFA 1200 score in patients with AML >60 years treated with double nucleoside-based low-intensity therapy. Blood Adv. 2022 10 11; 6(19):5546-5549.
PMID:
35201293
; PMCID:
PMC9647734
.
Citations:
Fields:
Hem
Hematology
Yacoub A, Borate U, Rampal R, Ali H, Wang E, Gerds A, Hobbs G, Kremyanskaya M, Winton E, O'Connell C, Goel S, Oh S, Schiller G, Assad A, Erickson-Viitanen S, Zhou F,
Daver N
. MPN-075 Efficacy and Safety of Add-on Parsaclisib to Ruxolitinib Therapy in Myelofibrosis Patients With Low Versus Higher Baseline Platelet Counts: A Subgroup Analysis of Data From a Phase 2 Study. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S324.
PMID:
36163982
.
Citations:
Borthakur G
, Ravandi F, Patel K, Wang X,
Kadia T
,
DiNardo C
,
Garcia-Manero G
,
Pemmaraju N
,
Jabbour EJ
,
Takahashi K
,
Ohanian M
,
Daver N
,
Alvarado Y
, Brandt M, Pierce S,
Kantarjian H
. Retrospective comparison of survival and responses to Fludarabine, Cytarabine, GCSF (FLAG) in combination with gemtuzumab ozogamicin (GO) or Idarubicin (IDA) in patients with newly diagnosed core binding factor (CBF) acute myelogenous leukemia: MD Anderson experience in 174 patients. Am J Hematol. 2022 Nov; 97(11):1427-1434.
PMID:
36053747
.
Citations:
Venugopal S,
DiNardo CD
,
Loghavi S
, Qiao W, Ravandi F,
Konopleva M
,
Kadia T
,
Bhalla K
,
Jabbour E
, Issa GC, Macaron W,
Daver N
,
Borthakur G
, Montalban-Bravo G, Yilmaz M,
Patel KP
, Kanagal-Shamanna R, Chien K, Maiti A,
Kantarjian H
, Short NJ. Differential prognostic impact of RUNX1 mutations according to frontline therapy in patients with acute myeloid leukemia. Am J Hematol. 2022 Dec; 97(12):1560-1567.
PMID:
36087091
.
Citations:
Fiskus W
,
Daver N
, Boettcher S, Mill CP, Sasaki K, Birdwell CE, Davis JA, Das K,
Takahashi K
,
Kadia TM
,
DiNardo CD
, Burrows F,
Loghavi S
,
Khoury JD
, Ebert BL,
Bhalla KN
. Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1. Leukemia. 2022 11; 36(11):2729-2733.
PMID:
36151141
; PMCID:
PMC9613474
.
Citations:
Lachowiez CA, Reville PK,
Kantarjian H
,
Jabbour E
,
Borthakur G
,
Daver N
, Issa G, Furudate K, Tanaka T, Pierce S, Tang G,
Patel KP
, Medeiros J, Abbas HA, Haddad F, Hammond D, Short NJ, Maiti A, Yilmaz M, Sasaki K,
Takahashi K
,
Pemmaraju N
,
Konopleva M
,
Garcia-Manero G
, Ravandi F,
Kadia TM
,
Loghavi S
,
DiNardo CD
. Contemporary outcomes in IDH-mutated acute myeloid leukemia: The impact of co-occurring NPM1 mutations and venetoclax-based treatment. Am J Hematol. 2022 Nov; 97(11):1443-1452.
PMID:
36054614
.
Citations:
Abbas HA, Ayoub E, Sun H, Kanagal-Shamanna R, Short NJ, Issa G, Yilmaz M, Pierce S, Rivera D, Cham B, Wing S, Li Z, Hammond D,
Jabbour E
,
Borthakur G
,
Garcia-Manero G
,
Andreeff M
,
Daver N
,
Kadia T
,
Konopleva M
,
DiNardo C
, Ravandi F. Clinical and molecular profiling of AML patients with chromosome 7 or 7q deletions in the context of TP53 alterations and venetoclax treatment. Leuk Lymphoma. 2022 12; 63(13):3105-3116.
PMID:
36089905
; PMCID:
PMC9772202
.
Citations:
Short NJ, Macaron W,
Kadia T
,
Dinardo C
, Issa GC,
Daver N
, Wang S,
Jorgensen J
, Nguyen D, Bidikian A,
Patel KP
,
Loghavi S
,
Konopleva M
, Yilmaz M,
Jabbour E
, Maiti A, Abbas HA,
Shpall E
,
Popat U
,
Al-Atrash G
, Pierce S,
Kantarjian HM
, Ravandi F. Clinical outcomes and impact of therapeutic intervention in patients with acute myeloid leukemia who experience measurable residual disease?(MRD) recurrence following MRD-negative remission. Am J Hematol. 2022 Nov; 97(11):E408-E411.
PMID:
36054774
.
Citations:
Maiti A,
Daver NG
. Eprenetapopt in the Post-Transplant Setting: Mechanisms and Future Directions. J Clin Oncol. 2022 Dec 01; 40(34):3994-3997.
PMID:
36070541
.
Citations:
Wei Y
, Zheng H, Lockyer PP, Darbaniyan F, Li Z, Kanagal-Shamanna R, Soltysiak KA, Yang H, Ganan-Gomez I, Montalban-Bravo G, Chien KS,
Do KA
,
Daver N
,
Garcia-Manero G
. MDM2 antagonist improves therapeutic activity of azacitidine in myelodysplastic syndromes and chronic myelomonocytic leukemia. Leuk Lymphoma. 2022 12; 63(13):3154-3164.
PMID:
36059252
; PMCID:
PMC10088064
.
Citations:
DiNardo CD
, Venugopal S, Lachowiez CA,
Takahashi K
,
Loghavi S
, Montalban-Bravo G, Wang X, Carraway HE, Sekeres MA, Sukkur A, Hammond D, Chien KS, Maiti A, Masarova L, Sasaki K,
Alvarado Y
,
Kadia TM
, Short NJ,
Daver NG
,
Borthakur G
, Ravandi F,
Kantarjian HM
, Patel BJ, DeZern AE, Roboz GJ,
Garcia-Manero G
. Targeted therapy with the mutant IDH2 inhibitor enasidenib for high-risk IDH2-mutant myelodysplastic syndrome. Blood Adv. 2022 Aug 16.
PMID:
35973199
.
Citations:
Daver N
, Perl AE, Maly J, Levis M, Ritchie E, Litzow M, McCloskey J, Smith CC, Schiller G, Bradley T, Tiu RV,
Naqvi K
, Dail M, Brackman D, Siddani S, Wang J, Chyla B, Lee P, Altman JK. Venetoclax Plus Gilteritinib for FLT3-Mutated Relapsed/Refractory Acute Myeloid Leukemia. J Clin Oncol. 2022 12 10; 40(35):4048-4059.
PMID:
35849791
; PMCID:
PMC9746764
.
Citations:
Fields:
Neo
Neoplasms
Daver N
, Jonas BA, Medeiros BC, Patil U, Yan M. Phase 1b, open-label study evaluating the safety and pharmacokinetics of atezolizumab (anti-PD-L1 antibody) administered in combination with Hu5F9-G4 to patients with relapsed and/or refractory acute myeloid leukemia. Leuk Lymphoma. 2022 11; 63(11):2711-2714.
PMID:
35834732
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Short NJ,
Kantarjian H
, Ravandi F,
Konopleva M
,
Jain N
, Kanagal-Shamanna R,
Patel KP
, Macaron W,
Kadia TM
, Wang S,
Jorgensen JL
,
Khoury JD
, Yilmaz M,
Kebriaei P
,
Takahashi K
,
Garcia-Manero G
,
Daver N
, Post SM, Huang X,
Kornblau SM
, Pelletier S, Flores W, Matthews J, Garris R,
Jabbour E
. High-sensitivity next-generation sequencing MRD assessment in ALL identifies patients at very low risk of relapse. Blood Adv. 2022 07 12; 6(13):4006-4014.
PMID:
35533262
; PMCID:
PMC9278301
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Tashakori M,
Kadia T
,
Loghavi S
,
Daver N
, Kanagal-Shamanna R, Pierce S, Sui D,
Wei P
, Khodakarami F,
Tang Z
,
Routbort M
, Bivins CA,
Jabbour EJ
,
Medeiros LJ
,
Bhalla K
,
Kantarjian HM
, Ravandi F,
Khoury JD
. TP53 copy number and protein expression inform mutation status across risk categories in acute myeloid leukemia. Blood. 2022 07 07; 140(1):58-72.
PMID:
35390143
; PMCID:
PMC9346958
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Desikan SP, Ravandi F,
Pemmaraju N
,
Konopleva M
,
Loghavi S
,
Jabbour EJ
,
Daver N
,
Jain N
, Chien KS, Maiti A, Montalban-Bravo G,
Kadia TM
, Macaron W, DeLumpa R, Kwari M,
Borthakur G
, Short NJ. A Phase II Study of Azacitidine, Venetoclax, and Trametinib in Relapsed or Refractory Acute Myeloid Leukemia Harboring RAS Pathway-Activating Mutations. Acta Haematol. 2022; 145(5):529-536.
PMID:
35717939
.
Citations:
Fields:
Hem
Hematology
Kadia TM
, Reville PK, Wang X, Rausch CR,
Borthakur G
,
Pemmaraju N
,
Daver NG
,
DiNardo CD
, Sasaki K, Issa GC,
Ohanian M
, Montalban-Bravo G, Short NJ,
Jain N
,
Ferrajoli A
,
Bhalla KN
,
Jabbour E
,
Takahashi K
, Malla R, Quagliato K, Kanagal-Shamanna R,
Popat UR
,
Andreeff M
,
Garcia-Manero G
,
Konopleva MY
, Ravandi F,
Kantarjian HM
. Phase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia. J Clin Oncol. 2022 Nov 20; 40(33):3848-3857.
PMID:
35704787
; PMCID:
PMC9671758
.
Citations:
Fields:
Neo
Neoplasms
Desikan SP,
Daver N
,
DiNardo C
,
Kadia T
,
Konopleva M
, Ravandi F. Resistance to targeted therapies: delving into FLT3 and IDH. Blood Cancer J. 2022 06 09; 12(6):91.
PMID:
35680852
; PMCID:
PMC9184476
.
Citations:
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Nelson BE, Ejezie CL, Stephen BA, Nardo M, Campbell E, Gong J,
Hong DS
,
Fu S
, Yap TA, Murphy MB,
Piha-Paul S
,
Daver NG
, Rojas-Hernandez CM,
Naing A
. Spectrum of Immune Checkpoint Inhibitor Anemias: Results From a Single Center, Early-Phase Clinical Trials Case Series Experience. J Hematol. 2022 Jun; 11(3):113-120.
PMID:
35837373
; PMCID:
PMC9275440
.
Citations:
Kim K, Bazinet A,
Loghavi S
,
Konopleva M
,
Bhalla K
,
Daver N
,
Khoury JD
,
Kadia T
, Wilson NR,
Curry JL
, Heberton M, Miller D, Pierce S,
Borthakur G
,
Pemmaraju N
. Major clinical response in a patient with leukemia cutis treated with the bromodomain inhibitor PLX51107 and azacitidine. Leuk Res. 2022 08; 119:106884.
PMID:
35691130
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
DiNardo CD
, Lachowiez CA,
Takahashi K
,
Loghavi S
,
Kadia T
,
Daver N
, Xiao L, Adeoti M, Short NJ, Sasaki K, Wang SA,
Borthakur G
, Issa G, Maiti A,
Alvarado Y
,
Pemmaraju N
, Bravo GM, Masarova L, Yilmaz M,
Jain N
,
Andreeff M
,
Garcia-Manero G
,
Kornblau S
, Ravandi F,
Jabbour E
,
Konopleva MY
,
Kantarjian HM
. Venetoclax combined with FLAG-IDA induction and consolidation in newly diagnosed acute myeloid leukemia. Am J Hematol. 2022 08; 97(8):1035-1043.
PMID:
35583199
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Zeng AGX, Bansal S, Jin L, Mitchell A, Chen WC, Abbas HA, Chan-Seng-Yue M, Voisin V, van Galen P, Tierens A, Cheok M, Preudhomme C,
Daver N
, Futreal PA, Minden MD, Kennedy JA, Wang JCY, Dick JE, Dombret H. A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia. Nat Med. 2022 06; 28(6):1212-1223.
PMID:
35618837
.
Citations:
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Pemmaraju N
, Wilson NR,
Garcia-Manero G
, Sasaki K,
Khoury JD
,
Jain N
,
Borthakur G
, Ravandi F,
Daver N
,
Kadia T
,
DiNardo C
,
Jabbour E
, Pierce S,
Qazilbash M
,
Konopleva M
,
Kantarjian H
. Characteristics and outcomes of patients with blastic plasmacytoid dendritic cell neoplasm treated with frontline HCVAD. Blood Adv. 2022 05 24; 6(10):3027-3035.
PMID:
35061885
; PMCID:
PMC9131912
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Tashakori M, Wang W,
Kadia TM
,
Daver NG
, Montalban-Bravo G,
Loghavi S
, Wang SA,
Medeiros LJ
, Ravandi F,
Khoury JD
. Differential characteristics of TP53 alterations in pure erythroid leukemia arising after exposure to cytotoxic therapy. Leuk Res. 2022 07; 118:106860.
PMID:
35636055
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Yilmaz M,
Kantarjian H
, Short NJ, Reville P,
Konopleva M
,
Kadia T
,
DiNardo C
,
Borthakur G
,
Pemmaraju N
, Maiti A,
Jabbour E
,
Jain N
, Issa G,
Takahashi K
, Sasaki K,
Ohanian M
, Pierce S, Tang G,
Loghavi S
, Patel K, Wang SA,
Garcia-Manero G
,
Andreeff M
, Ravandi F,
Daver N
. Hypomethylating agent and venetoclax with FLT3 inhibitor "triplet" therapy in older/unfit patients with FLT3 mutated AML. Blood Cancer J. 2022 05 02; 12(5):77.
PMID:
35501304
; PMCID:
PMC9061716
.
Citations:
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Lachowiez CA, Reville PK,
Kantarjian H
,
Jabbour E
,
Borthakur G
,
Daver N
,
Loghavi S
, Furudate K, Xiao L, Pierce S, Short NJ, Maiti A, Yilmaz M, Sasaki K,
Takahashi K
,
Konopleva M
,
Pemmaraju N
,
Popat U
,
Shpall E
,
Garcia-Manero G
, Ravandi F,
DiNardo CD
,
Kadia TM
. Venetoclax combined with induction chemotherapy in patients with newly diagnosed acute myeloid leukaemia: a post-hoc, propensity score-matched, cohort study. Lancet Haematol. 2022 May; 9(5):e350-e360.
PMID:
35483396
; PMCID:
PMC9946440
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Kim K,
Konopleva M
,
DiNardo CD
,
Borthakur G
,
Loghavi S
, Tang G,
Daver N
,
Pemmaraju N
,
Jabbour E
, Rausch CR, Yilmaz M, Sasaki K, Short NJ,
Jain N
, Brandt M, Pierce S,
Garcia-Manero G
, Ravandi F,
Kantarjian H
,
Kadia TM
. Urgent cytoreduction for newly diagnosed acute myeloid leukemia patients allows acquisition of pretreatment genomic data and enrollment on investigational clinical trials. Am J Hematol. 2022 07; 97(7):885-894.
PMID:
35413152
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Sheshadri A
, Goizueta AA,
Shannon VR
, London D,
Garcia-Manero G
,
Kantarjian HM
,
Ravandi-Kashani F
,
Kadia TM
,
Konopleva MY
,
DiNardo CD
, Pierce S, Zarifa A, Albittar AA, Zhong LL, Akhmedzhanov FO, Arain MH, Alfayez M, Alotaibi A, Altan M,
Naing A
,
Mendoza TR
,
Godoy MCB
,
Shroff G
, Kim ST,
Faiz SA
,
Kontoyiannis DP
, Khawaja F, Jennings K,
Daver NG
. Pneumonitis after immune checkpoint inhibitor therapies in patients with acute myeloid leukemia: A retrospective cohort study. Cancer. 2022 07 15; 128(14):2736-2745.
PMID:
35452134
; PMCID:
PMC9232977
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Short NJ,
Borthakur G
,
Pemmaraju N
,
Dinardo CD
,
Kadia TM
,
Jabbour E
,
Konopleva M
, Macaron W,
Ning J
, Ma J, Pierce S,
Alvarado Y
, Sasaki K,
Takahashi K
,
Estrov Z
, Masarova L, Issa GC, Montalban-Bravo G,
Andreeff M
,
Burger JA
, Miller D, Alexander L,
Naing A
,
Garcia-Manero G
, Ravandi F,
Daver N
. A multi-arm phase Ib/II study designed for rapid, parallel evaluation of novel immunotherapy combinations in relapsed/refractory acute myeloid leukemia. Leuk Lymphoma. 2022 09; 63(9):2161-2170.
PMID:
35442137
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Sasaki K, Ravandi F,
Kadia T
,
DiNardo C
,
Borthakur G
, Short N,
Jain N
,
Daver N
,
Jabbour E
,
Garcia-Manero G
,
Khoury J
,
Konoplev S
,
Loghavi S
, Patel K, Montalban-Bravo G, Masarova L,
Konopleva M
,
Kantarjian H
. Prediction of survival with intensive chemotherapy in acute myeloid leukemia. Am J Hematol. 2022 07; 97(7):865-876.
PMID:
35384048
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Haddad FG, Sasaki K, Issa GC,
Garcia-Manero G
, Ravandi F,
Kadia T
, Cortes J,
Konopleva M
,
Pemmaraju N
,
Alvarado Y
, Yilmaz M,
Borthakur G
,
DiNardo C
,
Jain N
,
Daver N
, Short NJ,
Jabbour E
,
Kantarjian H
. Treatment-free remission in patients with chronic myeloid leukemia following the discontinuation of tyrosine kinase inhibitors. Am J Hematol. 2022 07; 97(7):856-864.
PMID:
35357036
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Franklin S, Aitken SL, Shi Y, Sahasrabhojane PV, Robinson S, Peterson CB,
Daver N
, Ajami NA,
Kontoyiannis DP
,
Shelburne SA
, Galloway-Pe?a J. Oral and Stool Microbiome Coalescence and Its Association With Antibiotic Exposure in Acute Leukemia Patients. Front Cell Infect Microbiol. 2022; 12:848580.
PMID:
35433514
; PMCID:
PMC9010033
.
Citations:
Fields:
Cel
Cell Biology
Com
Communicable Diseases
Mic
Microbiology
Translation:
Humans
Maiti A,
Daver NG
. A nonstick marrow may help to fry leukemia. Blood. 2022 02 24; 139(8):1119-1121.
PMID:
35201330
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Senapati J, Shoukier M,
Garcia-Manero G
, Wang X, Patel K,
Kadia T
, Ravandi F,
Pemmaraju N
,
Ohanian M
,
Daver N
,
DiNardo C
,
Alvarado Y
, Aldrich J,
Borthakur G
. Activity of decitabine as maintenance therapy in core binding factor acute myeloid leukemia. Am J Hematol. 2022 05; 97(5):574-582.
PMID:
35150150
; PMCID:
PMC9303262
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Wurster S, Albert ND,
Bharadwaj U
,
Kasembeli MM
,
Tarrand JJ
,
Daver N
,
Kontoyiannis DP
. Blockade of the PD-1/PD-L1 Immune Checkpoint Pathway Improves Infection Outcomes and Enhances Fungicidal Host Defense in a Murine Model of Invasive Pulmonary Mucormycosis. Front Immunol. 2022; 13:838344.
PMID:
35251033
; PMCID:
PMC8896628
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Animals
Zoref-Lorenz A, Murakami J, Hofstetter L, Iyer S, Alotaibi AS, Mohamed SF, Miller PG, Guber E, Weinstein S, Yacobovich J, Nikiforow S, Ebert BL, Lane A, Pasvolsky O, Raanani P, Nagler A, Berliner N,
Daver N
, Ellis M, Jordan MB. An improved index for diagnosis and mortality prediction in malignancy-associated hemophagocytic lymphohistiocytosis. Blood. 2022 02 17; 139(7):1098-1110.
PMID:
34780598
; PMCID:
PMC8854682
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Mill CP,
Fiskus W
,
DiNardo CD
, Birdwell C, Davis JA,
Kadia TM
,
Takahashi K
, Short N,
Daver N
,
Ohanian M
,
Borthakur G
,
Kornblau SM
, Green MR, Qi Y, Su X,
Khoury JD
,
Bhalla KN
. Effective therapy for AML with RUNX1 mutation by cotreatment with inhibitors of protein translation and BCL2. Blood. 2022 02 10; 139(6):907-921.
PMID:
34601571
; PMCID:
PMC8832475
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Fiskus W
, Manshouri T, Birdwell C, Mill CP, Masarova L,
Bose P
,
Kadia TM
,
Daver N
,
DiNardo CD
,
Borthakur G
,
Khoury JD
,
Verstovsek S
,
Bhalla KN
. Efficacy of CDK9 inhibition in therapy of post-myeloproliferative neoplasm (MPN) secondary (s) AML cells. Blood Cancer J. 2022 01 31; 12(1):23.
PMID:
35102145
; PMCID:
PMC8803998
.
Citations:
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Short NJ, Venugopal S, Qiao W,
Kadia TM
, Ravandi F, Macaron W,
Dinardo CD
,
Daver N
,
Konopleva M
,
Borthakur G
,
Shpall EJ
,
Popat U
,
Champlin RE
,
Mehta R
,
Al-Atrash G
,
Oran B
,
Jabbour E
,
Garcia-Manero G
, Issa GC, Montalban-Bravo G, Yilmaz M, Maiti A,
Kantarjian H
. Impact of frontline treatment approach on outcomes in patients with secondary AML with prior hypomethylating agent exposure. J Hematol Oncol. 2022 01 29; 15(1):12.
PMID:
35093134
; PMCID:
PMC8800349
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Masarova L,
Bose P
,
Pemmaraju N
,
Daver NG
, Sasaki K, Chifotides HT, Zhou L,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Improved survival of patients with myelofibrosis in the last decade: Single-center experience. Cancer. 2022 04 15; 128(8):1658-1665.
PMID:
35077575
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Venugopal S,
Takahashi K
,
Daver N
, Maiti A,
Borthakur G
,
Loghavi S
, Short NJ,
Ohanian M
, Masarova L, Issa G, Wang X, Carlos BR, Yilmaz M,
Kadia T
,
Andreeff M
, Ravandi F,
Konopleva M
,
Kantarjian HM
,
DiNardo CD
. Efficacy and safety of enasidenib and azacitidine combination in patients with IDH2 mutated acute myeloid leukemia and not eligible for intensive chemotherapy. Blood Cancer J. 2022 01 25; 12(1):10.
PMID:
35078972
; PMCID:
PMC8789767
.
Citations:
4
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Fiskus W
, Boettcher S,
Daver N
, Mill CP, Sasaki K, Birdwell CE, Davis JA,
Takahashi K
,
Kadia TM
,
DiNardo CD
, Jin Q, Qi Y, Su X, McGeehan GM,
Khoury JD
, Ebert BL,
Bhalla KN
. Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c). Blood Cancer J. 2022 01 11; 12(1):5.
PMID:
35017466
; PMCID:
PMC8752621
.
Citations:
1
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Pasvolsky O, Daher M, Alatrash G,
Marin D
,
Daver N
, Ravandi F,
Rezvani K
,
Shpall E
,
Kebriaei P
. CARving the Path to Allogeneic CAR T Cell Therapy in Acute Myeloid Leukemia. Front Oncol. 2021; 11:800110.
PMID:
35083154
; PMCID:
PMC8784883
.
Citations:
Reville PK, Sasaki K,
Kantarjian HM
,
Daver NG
, Yilmaz M,
Dinardo CD
, Short NJ,
Borthakur G
,
Pemmaraju N
,
Mehta RS
, Pierce S,
Konoplev SN
,
Khoury JD
,
Garcia-Manero G
,
Konopleva MY
,
Jabbour E
, Ravandi F,
Kadia TM
. Improved outcomes among newly diagnosed patients with FMS-like tyrosine kinase 3 internal tandem duplication mutated acute myeloid leukemia treated with contemporary therapy: Revisiting the European LeukemiaNet adverse risk classification. Am J Hematol. 2022 03 01; 97(3):329-337.
PMID:
34981570
; PMCID:
PMC8884919
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Numan Y, Abdel Rahman Z, Grenet J, Boisclair S, Bewersdorf JP, Collins C, Barth D, Fraga M, Bixby DL, Zeidan AM, Yilmaz M, Desai P, Mannis G, Deutsch YE, Abaza Y, Dinner S, Frankfurt O, Litzow M, Al-Kali A, Foran JM, Sproat LZ, Jovanovic B,
Daver N
, Perl AE, Altman JK. Gilteritinib clinical activity in relapsed/refractory FLT3 mutated acute myeloid leukemia previously treated with FLT3 inhibitors. Am J Hematol. 2022 03 01; 97(3):322-328.
PMID:
34981560
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Haddad F, Zeidan AM,
Daver N
. Checkpoint Inhibitors and Other Immune-Based Therapies in Acute Myeloid Leukemia. Cancer J. 2022 Jan-Feb 01; 28(1):43-50.
PMID:
35072373
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
McCall D, Roth M, Mahadeo KM, Toepfer L, Nunez C, Short NJ,
Daver N
,
Kadia TM
,
DiNardo C
,
Yi JS
, Cuglievan B. Gilteritinib combination therapies in pediatric patients with FLT3-mutated acute myeloid leukemia. Blood Adv. 2021 12 14; 5(23):5215-5219.
PMID:
34592761
; PMCID:
PMC9153013
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Richard-Carpentier G,
Kantarjian HM
, Tang G, Yin CC,
Khoury JD
, Issa GC, Haddad F,
Jain N
, Ravandi F, Short NJ,
DiNardo CD
,
Takahashi K
,
Konopleva MY
,
Daver NG
,
Kadia T
,
Garcia-Manero G
, Garris R, O'Brien S,
Jabbour E
. Outcomes of acute lymphoblastic leukemia with KMT2A (MLL) rearrangement: the MD Anderson experience. Blood Adv. 2021 12 14; 5(23):5415-5419.
PMID:
34525185
; PMCID:
PMC9153023
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
El Hussein S,
Daver N
, Liu JL,
Kornblau S
, Fang H,
Konoplev S
,
Kantarjian H
,
Khoury JD
. Microsatellite Instability Assessment by Immunohistochemistry in Acute Myeloid Leukemia: A Reappraisal and Review of the Literature. Clin Lymphoma Myeloma Leuk. 2022 06; 22(6):e386-e391.
PMID:
34980577
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Abbas HA, Alaniz Z, Mackay S, Cyr M, Zhou J, Issa GC, Alfayez M, Matthews J,
Kornblau SM
,
Jabbour E
,
Garcia-Manero G
,
Konopleva M
,
Andreeff M
,
Daver N
. Single-cell polyfunctional proteomics of CD4 cells from patients with AML predicts responses to anti-PD-1-based therapy. Blood Adv. 2021 11 23; 5(22):4569-4574.
PMID:
34555853
; PMCID:
PMC8759127
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Cells
Sasaki K,
Kadia T
, Begna K,
DiNardo CD
,
Borthakur G
, Short NJ,
Jain N
,
Daver N
,
Jabbour E
,
Garcia-Manero G
, Bravo GM, Masarova L, Pierce S,
Konopleva M
, Ravandi F, Tefferi A,
Kantarjian H
. Prediction of early (4-week) mortality in acute myeloid leukemia with intensive chemotherapy. Am J Hematol. 2022 01 01; 97(1):68-78.
PMID:
34716921
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Tanaka T, Morita K,
Loghavi S
, Wang F, Furudate K, Sasaki Y, Little L, Gumbs C, Matthews J,
Daver N
,
Pemmaraju N
,
DiNardo CD
, Sasaki K, Yilmaz M,
Kadia TM
, Ravandi F,
Konopleva MY
,
Kantarjian HM
,
Champlin RE
,
Al-Atrash G
,
Garcia-Manero G
, Wang SA, Futreal PA,
Takahashi K
. Clonal dynamics and clinical implications of postremission clonal hematopoiesis in acute myeloid leukemia. Blood. 2021 11 04; 138(18):1733-1739.
PMID:
34115096
; PMCID:
PMC8569418
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Spallone A, Alotaibi AS, Jiang Y,
Daver N
,
Kontoyiannis DP
. Infectious Complications Among Patients With AML Treated With Immune Checkpoint Inhibitors. Clin Lymphoma Myeloma Leuk. 2022 05; 22(5):305-310.
PMID:
34810120
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Kantarjian H
, Short NJ,
DiNardo C
, Stein EM,
Daver N
, Perl AE, Wang ES, Wei A, Tallman M. Harnessing the benefits of available targeted therapies in acute myeloid leukaemia. Lancet Haematol. 2021 Dec; 8(12):e922-e933.
PMID:
34687602
; PMCID:
PMC8996707
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ramos Perez JM,
Patel KP
,
Loghavi S
,
Garcia-Manero G
,
Borthakur G
,
Jabbour E
,
Wierda W
, Pierce S, Brandt M,
Kornblau S
,
Kadia T
,
Daver N
,
DiNardo CD
,
Jain N
, Yilmaz M, Short N,
Verstovsek S
,
Ferrajoli A
,
Andreeff M
,
Konopleva M
, Rivera D, McCue D,
Kantarjian HM
, Ravandi F. Value of measurable residual disease monitoring in patients with acute promyelocytic leukemia in the era of frontline 'chemotherapy-free' therapy. Leuk Lymphoma. 2022 03; 63(3):672-675.
PMID:
34668451
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Abbas HA, Hao D, Tomczak K, Barrodia P, Im JS, Reville PK, Alaniz Z, Wang W, Wang R, Wang F,
Al-Atrash G
,
Takahashi K
, Ning J, Ding M, Beird HC, Mathews JT, Little L, Zhang J, Basu S,
Konopleva M
, Marques-Piubelli ML, Solis LM, Parra ER, Lu W, Tamegnon A,
Garcia-Manero G
, Green MR,
Sharma P
,
Allison JP
,
Kornblau SM
,
Rai K
, Wang L,
Daver N
,
Futreal A
. Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy. Nat Commun. 2021 10 18; 12(1):6071.
PMID:
34663807
; PMCID:
PMC8524723
.
Citations:
3
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Pemmaraju N
, Wilson NR,
Khoury JD
,
Jain N
,
Daver N
, Pierce S,
Jabbour E
,
Kadia T
,
DiNardo C
,
Garcia-Manero G
,
Qazilbash M
,
Konopleva M
,
Kantarjian H
. Central nervous system involvement in blastic plasmacytoid dendritic cell neoplasm. Blood. 2021 10 14; 138(15):1373-1377.
PMID:
34098573
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
Issa GC, Zarka J, Sasaki K, Qiao W, Pak D,
Ning J
, Short NJ, Haddad F,
Tang Z
,
Patel KP
, Cuglievan B,
Daver N
,
DiNardo CD
,
Jabbour E
,
Kadia T
,
Borthakur G
,
Garcia-Manero G
,
Konopleva M
,
Andreeff M
,
Kantarjian HM
, Ravandi F. Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements. Blood Cancer J. 2021 09 29; 11(9):162.
PMID:
34588432
; PMCID:
PMC8481264
.
Citations:
2
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Wei SC, Mancuso JJ,
Daver N
,
Allison JP
. Checkpoint Blockade + Chemotherapy: the Right Combination for AML? Blood Cancer Discov. 2021 Nov; 2(6):551-554.
PMID:
35015675
; PMCID:
PMC9894576
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Saxena K,
DiNardo C
,
Daver N
,
Konopleva M
. SOHO State of the Art Updates and Next Questions:Harnessing Apoptosis in AML. Clin Lymphoma Myeloma Leuk. 2022 03; 22(3):133-139.
PMID:
34602371
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Venugopal S, Maiti A,
DiNardo CD
, Qiao W,
Ning J
,
Loghavi S
,
Daver NG
,
Kadia TM
, Rausch CR,
Alvarado Y
,
Ohanian M
, Sasaki K, Short NJ,
Takahashi K
, Yilmaz M, Ravandi F,
Kantarjian HM
,
Konopleva MY
. Prognostic impact of conventional cytogenetics in acute myeloid leukemia treated with venetoclax and decitabine. Leuk Lymphoma. 2021 12; 62(14):3501-3505.
PMID:
34474640
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Maiti A,
Daver NG
. Lowering mTORC1 Drives CAR T-Cells Home in Acute Myeloid Leukemia. Clin Cancer Res. 2021 11 01; 27(21):5739-5741.
PMID:
34470774
; PMCID:
PMC8563411
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Pemmaraju N
,
Carter BZ
,
Bose P
,
Jain N
,
Kadia TM
,
Garcia-Manero G
,
Bueso-Ramos CE
,
DiNardo CD
, Bledsoe S,
Daver NG
,
Popat U
,
Konopleva MY
, Zhou L, Pierce S,
Estrov ZE
,
Borthakur GM
,
Ohanian M
, Qiao W, Masarova L, Wang X, Mak PY, Cortes J,
Jabbour E
,
Verstovsek S
. Final results of a phase 2 clinical trial of LCL161, an oral SMAC mimetic for patients with myelofibrosis. Blood Adv. 2021 08 24; 5(16):3163-3173.
PMID:
34424319
; PMCID:
PMC8405193
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Young PE, Kanagal-Shamanna R, Hu S, Tang G,
Thakral B
,
Daver N
, Issa GC, Medeiros LJ,
Konoplev S
. Chronic myeloid leukemia, BCR-ABL1-positive, carrying NPM1 mutation - First case series from a single institution. Leuk Res. 2021 12; 111:106685.
PMID:
34438119
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Alwash Y,
Khoury JD
, Tashakori M, Kanagal-Shamanna R,
Daver N
, Ravandi F,
Kadia TM
,
Konopleva M
,
Dinardo CD
, Issa GC,
Loghavi S
,
Takahashi K
,
Jabbour E
, Guerra V,
Kornblau S
,
Kantarjian H
, Short NJ. Development of TP53 mutations over the course of therapy for acute myeloid leukemia. Am J Hematol. 2021 11 01; 96(11):1420-1428.
PMID:
34351647
; PMCID:
PMC9167467
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Abbas HA, Reville PK, Geppner A, Rausch CR,
Pemmaraju N
,
Ohanian M
, Sasaki K,
Borthakur G
,
Daver N
,
DiNardo C
,
Bueso-Ramos C
, Pierce S,
Jabbour E
,
Garcia-Manero G
,
Konopleva M
, Ravandi F,
Kantarjian H
,
Kadia TM
. Clinical and molecular characterization of myeloid sarcoma without medullary leukemia. Leuk Lymphoma. 2021 12; 62(14):3402-3410.
PMID:
34380367
; PMCID:
PMC8939853
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Abou Dalle I,
Kantarjian H
,
Daver N
, Masarova L,
Pemmaraju N
, Bose P,
Garcia-Manero G
,
Verstovsek S
. Phase II study of single-agent nivolumab in patients with myelofibrosis. Ann Hematol. 2021 Dec; 100(12):2957-2960.
PMID:
34350483
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Abbas HA, Mohanty V, Wang R, Huang Y, Liang S, Wang F, Zhang J, Qiu Y, Hu CW, Qutub AA, Dail M, Bolen CR,
Daver N
,
Konopleva M
,
Futreal A
, Chen K, Wang L,
Kornblau SM
. Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes. Front Oncol. 2021; 11:705627.
PMID:
34422660
; PMCID:
PMC8372368
.
Citations:
1
Maiti A,
DiNardo CD
, Qiao W,
Kadia TM
,
Jabbour EJ
, Rausch CR,
Daver NG
, Short NJ,
Borthakur G
,
Pemmaraju N
, Yilmaz M,
Alvarado Y
, Montalbano KS, Wade A, Maduike RE, Guerrero JA, Vaughan K, Bivins CA, Pierce S,
Ning J
, Ravandi F,
Kantarjian HM
,
Konopleva MY
. Ten-day decitabine with venetoclax versus intensive chemotherapy in relapsed or refractory acute myeloid leukemia: A propensity score-matched analysis. Cancer. 2021 11 15; 127(22):4213-4220.
PMID:
34343352
; PMCID:
PMC8556232
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Chien KS, Kim K, Nogueras-Gonzalez GM,
Borthakur G
,
Naqvi K
,
Daver NG
, Montalban-Bravo G,
Cortes JE
,
DiNardo CD
,
Jabbour E
,
Alvarado Y
,
Andreeff M
,
Bose P
,
Jain N
,
Kadia TM
, Huang X, Sheppard KB, Klingner-Winton C, Pierce SA, Dong XQ, Soltysiak KA,
Kantarjian HM
,
Garcia-Manero G
. Phase II study of azacitidine with pembrolizumab in patients with intermediate-1 or higher-risk myelodysplastic syndrome. Br J Haematol. 2021 11; 195(3):378-387.
PMID:
34340254
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Kadia TM
, Reville PK,
Borthakur G
, Yilmaz M,
Kornblau S
,
Alvarado Y
,
Dinardo CD
,
Daver N
,
Jain N
,
Pemmaraju N
, Short N, Wang SA, Tidwell RSS, Islam R,
Konopleva M
,
Garcia-Manero G
, Ravandi F,
Kantarjian HM
. Venetoclax plus intensive chemotherapy with cladribine, idarubicin, and cytarabine in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a cohort from a single-centre, single-arm, phase 2 trial. Lancet Haematol. 2021 Aug; 8(8):e552-e561.
PMID:
34329576
; PMCID:
PMC8884174
.
Citations:
11
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Swaminathan M,
Kantarjian HM
, Levis M, Guerra V,
Borthakur G
,
Alvarado Y
,
DiNardo CD
,
Kadia T
,
Garcia-Manero G
,
Ohanian M
,
Daver N
,
Konopleva M
,
Pemmaraju N
,
Ferrajoli A
,
Andreeff M
,
Jain N
,
Estrov Z
,
Jabbour EJ
,
Wierda WG
, Pierce S, Pinsoy MR, Xiao L, Ravandi F,
Cortes JE
. A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome. Haematologica. 2021 08 01; 106(8):2121-2130.
PMID:
33853292
; PMCID:
PMC8327731
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kim K, Maiti A,
Loghavi S
, Pourebrahim R,
Kadia TM
, Rausch CR, Furudate K,
Daver NG
,
Alvarado Y
,
Ohanian M
, Sasaki K, Short NJ,
Takahashi K
, Yilmaz M, Tang G, Ravandi F,
Kantarjian HM
,
DiNardo CD
,
Konopleva MY
. Outcomes of TP53-mutant acute myeloid leukemia with decitabine and venetoclax. Cancer. 2021 10 15; 127(20):3772-3781.
PMID:
34255353
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Herbrich S, Baran N, Cai T, Weng C, Aitken MJL,
Post SM
, Henderson J, Shi C, Richard-Carpentier G, Sauvageau G,
Baggerly K
,
Al-Atrash G
, Davis RE,
Daver N
, Zha D,
Konopleva M
. Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML. J Immunother Cancer. 2021 07; 9(7).
PMID:
34326171
; PMCID:
PMC8323398
.
Citations:
4
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Srour SA,
Olson A
,
Ciurea SO
, Desai P,
Bashir Q
,
Oran B
,
Bose P
,
Mehta R
,
Patel KP
,
Pemmaraju N
,
Daver N
,
Verstovsek S
,
Champlin RE
,
Popat UR
. Mixed myeloid chimerism and relapse of myelofibrosis after allogeneic stem cell transplantation. Haematologica. 2021 07 01; 106(7):1988-1990.
PMID:
31296578
; PMCID:
PMC8252931
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
S Mehta R,
Torres Cabala CA
,
DiNardo CD
,
Daver N
,
Dabaja B
,
Rezvani K
,
Champlin RE
,
Shpall E
,
Duvic M
. Post-transplantation donor-derived Sezary syndrome in a patient with A91V PRF1 variant hemophagocytic lymphohistiocytosis. Am J Hematol. 2021 09 01; 96(9):E350-E353.
PMID:
34096089
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Venugopal S, Shoukier M,
Konopleva M
,
Dinardo CD
, Ravandi F, Short NJ,
Andreeff M
,
Borthakur G
,
Daver N
,
Pemmaraju N
, Sasaki K, Montalban-Bravo G, Marx KR, Pierce S,
Popat UR
,
Shpall EJ
, Kanagal-Shamanna R,
Garcia-Manero G
,
Kantarjian HM
,
Kadia TM
. Outcomes in patients with newly diagnosed TP53-mutated acute myeloid leukemia with or without venetoclax-based therapy. Cancer. 2021 10 01; 127(19):3541-3551.
PMID:
34182597
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Saxena K, Herbrich SM,
Pemmaraju N
,
Kadia TM
,
DiNardo CD
,
Borthakur G
, Pierce SA,
Jabbour E
, Wang SA,
Bueso-Ramos C
,
Loghavi S
, Tang G, Cheung CM, Alexander L,
Kornblau S
,
Andreeff M
,
Garcia-Manero G
, Ravandi F,
Konopleva MY
,
Daver N
. A phase 1b/2 study of azacitidine with PD-L1 antibody avelumab in relapsed/refractory acute myeloid leukemia. Cancer. 2021 10 15; 127(20):3761-3771.
PMID:
34171128
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Saxena K,
Jabbour E
, Issa G, Sasaki K, Ravandi F, Maiti A,
Daver N
,
Kadia T
,
DiNardo CD
,
Konopleva M
,
Cortes JE
, Yilmaz M, Chien K, Pierce S,
Kantarjian H
, Short NJ. Impact of frontline treatment approach on outcomes of myeloid blast phase CML. J Hematol Oncol. 2021 06 15; 14(1):94.
PMID:
34130720
; PMCID:
PMC8204504
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Wang J, Ma J, Cai C,
Daver N
,
Ning J
. A Bayesian hierarchical monitoring design for phase II cancer clinical trials: Incorporating information on response duration into monitoring rules. Stat Med. 2021 09 20; 40(21):4629-4639.
PMID:
34101217
; PMCID:
PMC8376777
.
Citations:
Fields:
Sta
Statistics as Topic
Translation:
Humans
Jain N
, Maiti A, Ravandi F,
Konopleva M
,
Daver N
,
Kadia T
,
Pemmaraju N
, Short N,
Kebriaei P
,
Ning J
, Cortes J,
Jabbour E
,
Kantarjian H
. Inotuzumab ozogamicin with bosutinib for relapsed or refractory Philadelphia chromosome positive acute lymphoblastic leukemia or lymphoid blast phase of chronic myeloid leukemia. Am J Hematol. 2021 08 01; 96(8):1000-1007.
PMID:
33991360
; PMCID:
PMC9096877
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
DiNardo CD
, Lachowiez CA,
Takahashi K
,
Loghavi S
, Xiao L,
Kadia T
,
Daver N
, Adeoti M, Short NJ, Sasaki K, Wang S,
Borthakur G
, Issa G, Maiti A,
Alvarado Y
,
Pemmaraju N
, Montalban Bravo G, Masarova L, Yilmaz M,
Jain N
,
Andreeff M
,
Jabbour E
,
Garcia-Manero G
,
Kornblau S
, Ravandi F,
Konopleva MY
,
Kantarjian HM
. Venetoclax Combined With FLAG-IDA Induction and Consolidation in Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia. J Clin Oncol. 2021 09 01; 39(25):2768-2778.
PMID:
34043428
; PMCID:
PMC8407653
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Daver N
, Venugopal S, Ravandi F. FLT3 mutated acute myeloid leukemia: 2021 treatment algorithm. Blood Cancer J. 2021 05 27; 11(5):104.
PMID:
34045454
; PMCID:
PMC8159924
.
Citations:
6
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Kadia TM
, Ravandi F,
Borthakur G
,
Konopleva M
,
DiNardo CD
,
Daver N
,
Pemmaraju N
, Kanagal-Shamanna R, Wang X, Huang X, Pierce S, Rausch C,
Burger J
,
Ferrajoli A
,
Jain N
,
Popat U
,
Estrov Z
,
Verstovsek S
,
Jabbour E
,
Garcia-Manero G
,
Kantarjian H
. Long-term results of low-intensity chemotherapy with clofarabine or cladribine combined with low-dose cytarabine alternating with decitabine in older patients with newly diagnosed acute myeloid leukemia. Am J Hematol. 2021 08 01; 96(8):914-924.
PMID:
33901324
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Fiskus W
, Mill CP, Nabet B, Perera D, Birdwell C, Manshouri T, Lara B,
Kadia TM
,
DiNardo C
,
Takahashi K
,
Daver N
,
Bose P
, Masarova L,
Pemmaraju N
,
Kornblau S
,
Borthakur G
, Montalban-Bravo G, Manero GG, Sharma S, Stubbs M, Su X, Green MR,
Coarfa C
,
Verstovsek S
,
Khoury JD
, Vakoc CR,
Bhalla KN
. Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells. Blood Cancer J. 2021 05 20; 11(5):98.
PMID:
34016956
; PMCID:
PMC8138012
.
Citations:
5
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Bose P
, McCue D, Wurster S, Wiederhold NP,
Konopleva M
,
Kadia TM
,
Borthakur G
, Ravandi F, Masarova L,
Takahashi K
,
Estrov Z
, Yilmaz M,
Daver N
,
Pemmaraju N
,
Naqvi K
, Rausch CR, Marx KR, Qiao W, Huang X, Bivins CA, Pierce SA,
Kantarjian HM
,
Kontoyiannis DP
. Isavuconazole as Primary Antifungal Prophylaxis in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome: An Open-label, Prospective, Phase 2 Study. Clin Infect Dis. 2021 05 18; 72(10):1755-1763.
PMID:
32236406
; PMCID:
PMC8130026
.
Citations:
10
Fields:
Com
Communicable Diseases
Translation:
Humans
CT
Clinical Trials
Haddad F,
Daver N
. Targeting CD47/SIRPa in Acute Myeloid Leukemia and Myelodysplastic Syndrome: Preclinical and Clinical Developments of Magrolimab. J Immunother Precis Oncol. 2021 May; 4(2):67-71.
PMID:
35663535
; PMCID:
PMC9153253
.
Citations:
1
Isidori A, Cerchione C,
Daver N
,
DiNardo C
,
Garcia-Manero G
,
Konopleva M
, Jabbour E, Ravandi F,
Kadia T
, Burguera AF, Loscocco F, Visani G, Martinelli G,
Kantarjian H
, Romano A, Curti A. Immunotherapy in Acute Myeloid Leukemia: Where We Stand. Front Oncol. 2021; 11:656218.
PMID:
34041025
; PMCID:
PMC8143531
.
Citations:
18
Yilmaz M,
Daver N
,
Borthakur G
,
Kadia T
,
DiNardo C
, Kanagal-Shamanna R,
Loghavi S
,
Oran B
,
Popat UR
, Pierce S,
Jabbour E
, Short NJ, Issa G,
Ohanian M
,
Konopleva M
, Patel K,
Kantarjian H
, Ravandi F. FLT3 inhibitor based induction and allogeneic stem cell transplant in complete remission 1 improve outcomes in patients with newly diagnosed Acute Myeloid Leukemia with very low FLT3 allelic burden. Am J Hematol. 2021 08 01; 96(8):E275-E279.
PMID:
33891709
; PMCID:
PMC9154045
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Daver N
, Alotaibi AS, Subklewe M, B?cklein V. T-cell-based immunotherapy of acute myeloid leukemia: current concepts and future developments. Leukemia. 2021 07; 35(7):1843-1863.
PMID:
33953290
; PMCID:
PMC8257483
.
Citations:
30
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Montalban-Bravo G, Kanagal-Shamanna R, Sasaki K, Masarova L,
Naqvi K
,
Jabbour E
,
DiNardo CD
,
Takahashi K
,
Konopleva M
,
Pemmaraju N
,
Kadia TM
, Ravandi F,
Daver N
,
Borthakur G
,
Estrov Z
,
Khoury JD
,
Loghavi S
, Soltysiak KA, Pierce S,
Bueso-Ramos C
,
Patel KP
,
Verstovsek S
,
Kantarjian HM
,
Bose P
,
Garcia-Manero G
. Clinicopathologic correlates and natural history of atypical chronic myeloid leukemia. Cancer. 2021 09 01; 127(17):3113-3124.
PMID:
33914911
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Masarova L,
DiNardo CD
,
Bose P
,
Pemmaraju N
,
Daver NG
,
Kadia TM
, Chifotides HT, Zhou L,
Borthakur G
,
Estrov Z
,
Konopleva M
,
Verstovsek S
. Single-center experience with venetoclax combinations in patients with newly diagnosed and relapsed AML evolving from MPNs. Blood Adv. 2021 04 27; 5(8):2156-2164.
PMID:
33885751
; PMCID:
PMC8095138
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Lachowiez CA,
Loghavi S
, Furudate K, Montalban-Bravo G, Maiti A,
Kadia T
,
Daver N
,
Borthakur G
,
Pemmaraju N
, Sasaki K,
Alvarado Y
, Yilmaz M, Short NJ, Chien K,
Ohanian M
, Pierce S,
Patel KP
,
Jabbour E
, Ravandi F,
Kantarjian HM
,
Garcia-Manero G
,
Takahashi K
,
Konopleva MY
,
DiNardo CD
. Impact of splicing mutations in acute myeloid leukemia treated with hypomethylating agents combined with venetoclax. Blood Adv. 2021 04 27; 5(8):2173-2183.
PMID:
33885753
; PMCID:
PMC8095152
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Montalban-Bravo G, Kanagal-Shamanna R, Darbaniyan F, Siddiqui MT, Sasaki K,
Wei Y
, Yang H, Chien KS,
Naqvi K
,
Jabbour E
,
Kadia TM
,
Daver N
,
DiNardo C
, Ravandi F,
Pemmaraju N
,
Bose P
,
Verstovsek S
, Pierce S,
Bueso-Ramos C
, Patel K,
Do KA
,
Kantarjian H
,
Garcia-Manero G
. Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) and myelodysplastic syndrome with ring sideroblasts (MDS-RS). Am J Hematol. 2021 07 01; 96(7):E246-E249.
PMID:
33811786
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Maiti A,
DiNardo CD
, Wang SA,
Jorgensen J
,
Kadia TM
,
Daver NG
, Short NJ, Yilmaz M,
Pemmaraju N
,
Borthakur G
,
Bose P
, Issa GC,
Ferrajoli A
,
Jabbour EJ
,
Jain N
,
Garcia-Manero G
,
Ohanian M
,
Takahashi K
, Montalban-Bravo G, Masarova L,
Burger JA
, Thompson PA,
Verstovsek S
, Sasaki K,
Andreeff M
, Rausch CR, Montalbano KS, Pierce S, Qiao W, Ning J,
Kantarjian HM
,
Konopleva MY
, Ravandi F. Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia. Blood Adv. 2021 04 13; 5(7):1876-1883.
PMID:
33792630
; PMCID:
PMC8045494
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Montalban-Bravo G, Hammond D,
DiNardo CD
,
Konopleva M
,
Borthakur G
, Short NJ, Ramos-Perez J, Guerra V, Kanagal-Shamanna R,
Naqvi K
, Sasaki K,
Jabbour E
,
Pemmaraju N
,
Kadia TM
, Ravandi F,
Daver N
,
Estrov Z
, Pierce S,
Kantarjian H
,
Garcia-Manero G
. Activity of venetoclax-based therapy in chronic myelomonocytic leukemia. Leukemia. 2021 05; 35(5):1494-1499.
PMID:
33846541
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Short NJ,
Konopleva M
,
Kadia T
,
Kebriaei P
,
Daver N
, Huang X, Masarova L, Cook R,
Jain N
,
Jabbour E
,
Kantarjian H
, Ravandi F. An effective chemotherapy-free regimen of ponatinib plus venetoclax for relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Am J Hematol. 2021 07 01; 96(7):E229-E232.
PMID:
33780038
; PMCID:
PMC9278812
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Cells
Tambaro FP, Singh H, Jones E,
Rytting M
, Mahadeo KM, Thompson P,
Daver N
,
DiNardo C
,
Kadia T
,
Garcia-Manero G
, Chan T, Shah RR,
Wierda WG
. Autologous CD33-CAR-T cells for treatment of relapsed/refractory acute myelogenous leukemia. Leukemia. 2021 11; 35(11):3282-3286.
PMID:
33833386
; PMCID:
PMC8550958
.
Citations:
15
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Shah MV,
Saliba RM
, Varma A,
Ciurea SO
,
Oran B
,
Olson A
,
Bose P
,
Bashir Q
, Masarova L,
Alousi AM
, Srour S,
Mehta RS
,
Daver N
,
Pemmaraju N
,
Verstovsek S
,
Champlin RE
,
Popat UR
. Allogeneic stem cell transplant for patients with myeloproliferative neoplasms in blast phase: improving outcomes in the recent era. Br J Haematol. 2021 06; 193(5):1004-1008.
PMID:
33821472
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Morita K,
Kantarjian HM
, Sasaki K, Issa GC,
Jain N
,
Konopleva M
, Short NJ,
Takahashi K
,
DiNardo CD
,
Kadia TM
,
Garcia-Manero G
,
Daver N
, Montalban Bravo G,
Cortes JE
, Ravandi F,
Jabbour E
. Outcome of patients with chronic myeloid leukemia in lymphoid blastic phase and Philadelphia chromosome-positive acute lymphoblastic leukemia treated with hyper-CVAD and dasatinib. Cancer. 2021 08 01; 127(15):2641-2647.
PMID:
33823073
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Wei AH,
Daver N
. Taking aim at IDH in fitter patients with AML. Blood. 2021 04 01; 137(13):1706-1707.
PMID:
33792680
; PMCID:
PMC9999040
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Sasaki K,
Kantarjian HM
, Short NJ, Samra B,
Khoury JD
,
Kanagal Shamanna R
,
Konopleva M
,
Jain N
,
DiNardo CD
, Khouri R,
Garcia-Manero G
,
Kadia TM
,
Wierda WG
,
Khouri IF
,
Kebriaei P
,
Mehta RS
,
Champlin RE
, Garris R, Cheung CM,
Daver N
, Thompson PA, Yilmaz M, Ravandi F,
Jabbour E
. Prognostic factors for progression in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia in complete molecular response within 3 months of therapy with tyrosine kinase inhibitors. Cancer. 2021 08 01; 127(15):2648-2656.
PMID:
33793964
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Rausch CR,
DiNardo CD
, Maiti A, Jammal NJ,
Kadia TM
, Marx KR,
Borthakur G
, Savoy JM,
Pemmaraju N
, DiPippo AJ,
Daver NG
, Chew SM, Sasaki K, Issa GC, Short NJ,
Takahashi K
,
Ohanian MN
,
Ning J
, Xiao L,
Alvarado Y
,
Kontoyiannis DP
, Ravandi F,
Kantarjian HM
,
Konopleva MY
. Duration of cytopenias with concomitant venetoclax and azole antifungals in acute myeloid leukemia. Cancer. 2021 07 15; 127(14):2489-2499.
PMID:
33793970
; PMCID:
PMC8249340
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Zeng Z
, Ly C,
Daver N
, Cortes J,
Kantarjian HM
,
Andreeff M
,
Konopleva M
. High-throughput proteomic profiling reveals mechanisms of action of AMG925, a dual FLT3-CDK4/6 kinase inhibitor targeting AML and AML stem/progenitor cells. Ann Hematol. 2021 Jun; 100(6):1485-1496.
PMID:
33787984
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Cerchione C,
Daver N
,
DiNardo C
,
Jabbour EJ
,
Konopleva M
,
Ravandi-Kashani F
,
Kadia T
, Martelli MP, Isidori A, Martinelli G,
Kantarjian H
, Romano A. IDH1/IDH2 Inhibition in Acute Myeloid Leukemia. Front Oncol. 2021; 11:639387.
PMID:
33898313
; PMCID:
PMC8063727
.
Citations:
7
Reville PK,
Kantarjian HM
, Ravandi F,
Jabbour E
,
DiNardo CD
,
Daver N
,
Pemmaraju N
,
Ohanian M
,
Alvarado Y
, Xiao L, Alatrash G,
Loghavi S
, Rausch CR,
Borthakur G
,
Konopleva M
, Cortes J,
Kadia TM
. Nivolumab maintenance in high-risk acute myeloid leukemia patients: a single-arm, open-label, phase II study. Blood Cancer J. 2021 03 17; 11(3):60.
PMID:
33731681
; PMCID:
PMC7969746
.
Citations:
2
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Daver N
, Salhotra A, Brandwein JM, Podoltsev NA, Pollyea DA, Jurcic JG, Assouline S, Yee K, Li M, Pourmohamad T, Samineni D, Sumiyoshi T, Vaze A, Dere RC, Ma C, Cooper J. A Phase I dose-escalation study of DCLL9718S, an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1) in patients with acute myeloid leukemia. Am J Hematol. 2021 05 01; 96(5):E175-E179.
PMID:
33617672
; PMCID:
PMC8252033
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kanagal-Shamanna R, Montalban-Bravo G,
Katsonis P
, Sasaki K, Class CA,
Jabbour E
, Sallman D, Hunter AM, Benton C, Chien KS,
Luthra R
,
Bueso-Ramos CE
,
Kadia T
,
Andreeff M
, Komrokji RS, Al Ali NH, Short N,
Daver N
,
Routbort MJ
,
Khoury JD
, Patel K, Ganan-Gomez I,
Wei Y
,
Borthakur G
, Ravandi F,
Do KA
, Soltysiak KA,
Lichtarge O
,
Medeiros LJ
,
Kantarjian H
,
Garcia-Manero G
. Evolutionary action score identifies a subset of TP53 mutated myelodysplastic syndrome with favorable prognosis. Blood Cancer J. 2021 03 06; 11(3):52.
PMID:
33677472
; PMCID:
PMC7936977
.
Citations:
2
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Maiti A, Rausch CR,
Cortes JE
,
Pemmaraju N
,
Daver NG
, Ravandi F,
Garcia-Manero G
,
Borthakur G
,
Naqvi K
,
Ohanian M
, Short NJ,
Alvarado Y
,
Kadia TM
,
Takahashi K
, Yilmaz M,
Jain N
,
Kornblau S
, Montalban Bravo G, Sasaki K,
Andreeff M
, Bose P,
Ferrajoli A
, Issa GC,
Jabbour EJ
, Masarova L, Thompson PA, Wang S,
Konoplev S
, Pierce SA,
Ning J
, Qiao W, Welch JS,
Kantarjian HM
,
DiNardo CD
,
Konopleva MY
. Outcomes of relapsed or refractory acute myeloid leukemia after frontline hypomethylating agent and venetoclax regimens. Haematologica. 2021 03 01; 106(3):894-898.
PMID:
32499238
; PMCID:
PMC7927994
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Venugopal S,
Daver N
, Ravandi F. An Update on the Clinical Evaluation of Antibody-Based Therapeutics in Acute Myeloid Leukemia. Curr Hematol Malig Rep. 2021 02; 16(1):89-96.
PMID:
33630233
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Yilmaz M, Alfayez M,
DiNardo CD
,
Borthakur G
,
Kadia TM
,
Konopleva MY
,
Loghavi S
, Kanagal-Shamanna R,
Patel KP
,
Jabbour EJ
,
Garcia-Manero G
,
Pemmaraju N
, Pierce SA, Ghayas I, Short NJ, Montalban-Bravo G,
Takahashi K
, Assi R, Alotaibi AS,
Ohanian M
,
Andreeff M
,
Cortes JE
,
Kantarjian HM
, Ravandi F,
Daver NG
. Correction to: Outcomes with sequential FLT3-inhibitor-based therapies in patients with AML. J Hematol Oncol. 2021 Feb 23; 14(1):34.
PMID:
33618754
; PMCID:
PMC7901199
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Kantarjian H
,
Kadia T
,
DiNardo C
,
Daver N
,
Borthakur G
,
Jabbour E
,
Garcia-Manero G
,
Konopleva M
, Ravandi F. Acute myeloid leukemia: current progress and future directions. Blood Cancer J. 2021 02 22; 11(2):41.
PMID:
33619261
; PMCID:
PMC7900255
.
Citations:
45
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Loghavi S
,
DiNardo CD
, Furudate K,
Takahashi K
, Tanaka T, Short NJ,
Kadia T
,
Konopleva M
, Kanagal-Shamanna R, Farnoud NR, Pierce S,
Khoury JD
,
Jorgensen JL
,
Patel KP
,
Daver N
, Yilmaz M,
Medeiros LJ
,
Kantarjian H
, Ravandi F, Wang SA. Flow cytometric immunophenotypic alterations of persistent clonal haematopoiesis in remission bone marrows of patients with NPM1-mutated acute myeloid leukaemia. Br J Haematol. 2021 03; 192(6):1054-1063.
PMID:
33618432
; PMCID:
PMC8944196
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Venugopal S, Maiti A,
DiNardo CD
,
Loghavi S
,
Daver NG
,
Kadia TM
, Rausch CR,
Alvarado Y
,
Ohanian M
, Sasaki K, Short NJ,
Takahashi K
, Yilmaz M, Ravandi F,
Kantarjian HM
,
Konopleva MY
. Decitabine and venetoclax for IDH1/2-mutated acute myeloid leukemia. Am J Hematol. 2021 05 01; 96(5):E154-E157.
PMID:
33580980
; PMCID:
PMC8237705
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Saberian C, Abdel-Wahab N,
Abudayyeh A
, Rafei H, Joseph J,
Rondon G
, Whited L, Gruschkus S, Fa'ak F, Daher M, Knape C, Safa H, Shoukier M,
Suarez-Almazor ME
, Marcotulli M, Ludford K, Gulbis AM,
Konopleva M
,
Ohanian M
, Ravandi F,
Garcia-Manero G
,
Oran B
,
Popat UR
, Mehta R,
Alousi AM
,
Daver N
,
Champlin R
,
Diab A
,
Al-Atrash G
. Post-transplantation cyclophosphamide reduces the incidence of acute graft-versus-host disease in patients with acute myeloid leukemia/myelodysplastic syndromes who receive immune checkpoint inhibitors after allogeneic hematopoietic stem cell transplantation. J Immunother Cancer. 2021 02; 9(2).
PMID:
33637601
; PMCID:
PMC7919586
.
Citations:
2
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Maiti A,
DiNardo CD
,
Daver NG
, Rausch CR, Ravandi F,
Kadia TM
,
Pemmaraju N
,
Borthakur G
,
Bose P
, Issa GC, Short NJ, Yilmaz M, Montalban-Bravo G,
Ferrajoli A
,
Jabbour EJ
,
Jain N
,
Ohanian M
,
Takahashi K
, Thompson PA,
Loghavi S
, Montalbano KS, Pierce S,
Wierda WG
,
Kantarjian HM
,
Konopleva MY
. Triplet therapy with venetoclax, FLT3 inhibitor and decitabine for FLT3-mutated acute myeloid leukemia. Blood Cancer J. 2021 02 01; 11(2):25.
PMID:
33563904
; PMCID:
PMC7873265
.
Citations:
11
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Daver N
. Immune checkpoint inhibitors in acute myeloid leukemia. Best Pract Res Clin Haematol. 2021 03; 34(1):101247.
PMID:
33762102
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
Bannon SA,
Routbort MJ
, Montalban-Bravo G,
Mehta RS
, Jelloul FZ,
Takahashi K
,
Daver N
,
Oran B
,
Pemmaraju N
,
Borthakur G
,
Naqvi K
, Issa G, Sasaki K,
Alvarado Y
,
Kadia TM
,
Konopleva M
, Shamanna RK,
Khoury JD
, Ravandi F,
Champlin R
,
Kantarjian HM
,
Bhalla K
,
Garcia-Manero G
,
Patel KP
,
DiNardo CD
. Next-Generation Sequencing of DDX41 in Myeloid Neoplasms Leads to Increased Detection of Germline Alterations. Front Oncol. 2020; 10:582213.
PMID:
33585199
; PMCID:
PMC7878971
.
Citations:
5
Kim ST,
Sheshadri A
,
Shannon V
,
Kontoyiannis DP
,
Kantarjian H
,
Garcia-Manero G
, Ravandi F,
Im JS
, Boddu P,
Bashoura L
,
Balachandran DD
,
Evans SE
,
Faiz S
, Ruiz Vazquez W,
Divenko M
,
Mathur R
, Tippen SP, Gumbs C,
Neelapu SS
,
Naing A
, Wang L,
Diab A
,
Futreal A
,
Nurieva R
,
Daver N
. Distinct Immunophenotypes of T Cells in Bronchoalveolar Lavage Fluid From Leukemia Patients With Immune Checkpoint Inhibitors-Related Pulmonary Complications. Front Immunol. 2020; 11:590494.
PMID:
33552049
; PMCID:
PMC7859512
.
Citations:
4
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Abou Dalle I,
Kantarjian HM
, Ravandi F,
Daver N
, Wang X,
Jabbour E
,
Estrov Z
,
DiNardo CD
,
Pemmaraju N
,
Ferrajoli A
,
Jain N
, Wang SA, Jammal N,
Borthakur G
,
Naqvi K
, Pelletier S, Pierce S,
Andreeff M
,
Garcia-Manero G
,
Cortes JE
,
Kadia TM
. Phase 2 study of lenalidomide maintenance for patients with high-risk acute myeloid leukemia in remission. Cancer. 2021 06 01; 127(11):1894-1900.
PMID:
33449377
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Morita K,
Jabbour E
, Ravandi F,
Borthakur G
,
Khoury JD
, Hu S,
Garcia-Manero G
,
Wierda W
, Issa G,
Daver N
,
Pemmaraju N
, Montalban-Bravo G, Soltysiak KA, Pierce S,
Bueso-Ramos C
, Cortes J, Sasaki K. Clinical Outcomes of Patients With Chronic Myeloid Leukemia With Concurrent Core Binding Factor Rearrangement and Philadelphia Chromosome. Clin Lymphoma Myeloma Leuk. 2021 05; 21(5):338-344.
PMID:
33597098
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Masarova L,
Bose P
,
Pemmaraju N
,
Daver N
, Zhou L, Pierce S,
Kantarjian H
,
Estrov Z
,
Verstovsek S
. Clinical Significance of Bone Marrow Blast Percentage in Patients With Myelofibrosis and the Effect of Ruxolitinib Therapy. Clin Lymphoma Myeloma Leuk. 2021 05; 21(5):318-327.e6.
PMID:
33551345
; PMCID:
PMC8849582
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Haddad F,
Daver N
. An Update on Immune Based Therapies in Acute Myeloid Leukemia: 2021 and Beyond! Adv Exp Med Biol. 2021; 1342:273-295.
PMID:
34972969
.
Citations:
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Cells
Maiti A, Qiao W, Sasaki K, Ravandi F,
Kadia TM
,
Jabbour EJ
,
Daver NG
,
Borthakur G
,
Garcia-Manero G
, Pierce SA, Montalbano KS,
Pemmaraju N
,
Naqvi K
,
Ohanian M
, Short NJ,
Alvarado Y
,
Takahashi K
, Yilmaz M,
Jain N
,
Kornblau SM
,
Andreeff M
,
Bose P
,
Ferrajoli A
, Issa GC, Masarova L, Thompson PA, Rausch CR,
Ning J
,
Kantarjian HM
,
DiNardo CD
,
Konopleva MY
. Venetoclax with decitabine vs intensive chemotherapy in acute myeloid leukemia: A propensity score matched analysis stratified by risk of treatment-related mortality. Am J Hematol. 2021 03 01; 96(3):282-291.
PMID:
33264443
; PMCID:
PMC8128145
.
Citations:
15
Fields:
Hem
Hematology
Translation:
Humans
Short NJ, Rafei H,
Daver N
, Hwang H, Ning J,
Jorgensen JL
,
Kadia TM
,
DiNardo CD
, Wang SA,
Jabbour E
,
Popat U
,
Oran B
, Cortes J,
Konopleva M
, Yilmaz M, Issa GC,
Kantarjian H
, Ravandi F. Prognostic impact of complete remission with MRD negativity in patients with relapsed or refractory AML. Blood Adv. 2020 12 22; 4(24):6117-6126.
PMID:
33351107
; PMCID:
PMC7757010
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Alotaibi AS, Yilmaz M, Kanagal-Shamanna R,
Loghavi S
,
Kadia TM
,
DiNardo CD
,
Borthakur G
,
Konopleva M
, Pierce SA, Wang SA, Tang G, Guerra V, Samra B,
Pemmaraju N
,
Jabbour E
, Short NJ, Issa GC,
Ohanian M
,
Garcia-Manero G
,
Bhalla KN
,
Patel KP
,
Takahashi K
,
Andreeff M
,
Cortes JE
,
Kantarjian HM
, Ravandi F,
Daver N
. Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 inhibitors. Blood Cancer Discov. 2021 03; 2(2):125-134.
PMID:
33681815
; PMCID:
PMC7935111
.
Citations:
9
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Sasaki K,
Jabbour EJ
, Ravandi F,
Konopleva M
,
Borthakur G
,
Wierda WG
,
Daver N
,
Takahashi K
,
Naqvi K
,
DiNardo C
, Montalban-Bravo G, Kanagal-Shamanna R, Issa G, Jain P, Skinner J, Rios MB, Pierce S, Soltysiak KA, Sato J,
Garcia-Manero G
,
Cortes JE
. The LEukemia Artificial Intelligence Program (LEAP) in chronic myeloid leukemia in chronic phase: A model to improve patient outcomes. Am J Hematol. 2021 02 01; 96(2):241-250.
PMID:
33180322
; PMCID:
PMC9022629
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Short NJ, Montalban-Bravo G, Hwang H, Ning J, Franquiz MJ, Kanagal-Shamanna R,
Patel KP
,
DiNardo CD
, Ravandi F,
Garcia-Manero G
,
Takahashi K
,
Konopleva M
,
Daver N
, Issa GC,
Andreeff M
,
Kantarjian H
,
Kadia TM
. Prognostic and therapeutic impacts of mutant TP53 variant allelic frequency in newly diagnosed acute myeloid leukemia. Blood Adv. 2020 11 24; 4(22):5681-5689.
PMID:
33211826
; PMCID:
PMC7686900
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Montalban-Bravo G, Kanagal-Shamanna R, Guerra V, Ramos-Perez J, Hammond D, Shilpa P,
Naqvi K
, Sasaki K,
Jabbour E
,
DiNardo C
,
Takahashi K
,
Konopleva M
,
Pemmaraju N
,
Kadia T
, Ravandi F,
Daver N
,
Borthakur G
,
Estrov Z
,
Khoury JD
,
Loghavi S
, Pierce S,
Bueso-Ramos C
, Patel K,
Kantarjian H
,
Garcia-Manero G
. Clinical outcomes and influence of mutation clonal dominance in oligomonocytic and classical chronic myelomonocytic leukemia. Am J Hematol. 2021 02 01; 96(2):E50-E53.
PMID:
33156969
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Chifotides HT, Masarova L, Alfayez M,
Daver N
,
Alvarado Y
,
Jabbour E
,
Konopleva M
,
Kantarjian HM
,
Patel KP
,
DiNardo CD
,
Verstovsek S
. Outcome of patients with IDH1/2-mutated post-myeloproliferative neoplasm AML in the era of IDH inhibitors. Blood Adv. 2020 11 10; 4(21):5336-5342.
PMID:
33112940
; PMCID:
PMC7656917
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Samra B,
Konopleva M
, Isidori A,
Daver N
,
DiNardo C
. Venetoclax-Based Combinations in Acute Myeloid Leukemia: Current Evidence and Future Directions. Front Oncol. 2020; 10:562558.
PMID:
33251134
; PMCID:
PMC7675064
.
Citations:
10
Koshy AG,
Daver NG
, Fathi AT. A new era of immuno-oncology in acute myeloid leukemia - antibody-based therapies and immune checkpoint inhibition. Best Pract Res Clin Haematol. 2020 12; 33(4):101220.
PMID:
33279176
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Daver N
, Wei AH, Pollyea DA, Fathi AT, Vyas P,
DiNardo CD
. New directions for emerging therapies in acute myeloid leukemia: the next chapter. Blood Cancer J. 2020 10 30; 10(10):107.
PMID:
33127875
; PMCID:
PMC7599225
.
Citations:
28
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Shoukier M,
Kadia T
,
Konopleva M
, Alotaibi AS, Alfayez M,
Loghavi S
,
Patel KP
, Kanagal-Shamanna R, Cortes J, Samra B,
Jabbour E
,
Garcia-Manero G
,
Takahashi K
, Pierce S, Short NJ, Yilmaz M, Sasaki K, Masarova L,
Pemmaraju N
,
Borthakur G
,
Kantarjian HM
, Ravandi F,
DiNardo CD
,
Daver N
. Clinical characteristics and outcomes in patients with acute myeloid leukemia with concurrent FLT3-ITD and IDH mutations. Cancer. 2021 02 01; 127(3):381-390.
PMID:
33119202
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Alotaibi AS, Yilmaz M,
Loghavi S
,
DiNardo C
,
Borthakur G
,
Kadia TM
,
Thakral B
,
Pemmaraju N
, Issa GC,
Konopleva M
, Short NJ, Patel K, Tang G, Ravandi F,
Daver N
. Emergence of BCR-ABL1 Fusion in AML Post-FLT3 Inhibitor-Based Therapy: A Potentially Targetable Mechanism of Resistance - A Case Series. Front Oncol. 2020; 10:588876.
PMID:
33194747
; PMCID:
PMC7606916
.
Citations:
3
Yilmaz M, Alfayez M,
DiNardo CD
,
Borthakur G
,
Kadia TM
,
Konopleva MY
,
Loghavi S
, Kanagal-Shamanna R,
Patel KP
,
Jabbour EJ
,
Garcia-Manero G
,
Pemmaraju N
, Pierce SA, Ghayas I, Short NJ, Montalban-Bravo G,
Takahashi K
, Assi R, Alotaibi AS,
Ohanian M
,
Andreeff M
,
Cortes JE
,
Kantarjian HM
, Ravandi F,
Daver NG
. Outcomes with sequential FLT3-inhibitor-based therapies in patients with AML. J Hematol Oncol. 2020 10 08; 13(1):132.
PMID:
33032648
; PMCID:
PMC7542942
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Sasaki K, Montalban-Bravo G, Kanagal-Shamanna R,
Jabbour E
, Ravandi F,
Kadia T
,
Daver N
,
Pemmaraju N
,
Konopleva M
,
Borthakur G
,
Takahashi K
, Patel K, Soltysiak KA, Chien KS, Sakurai K, Pierce S,
Kantarjian HM
,
Garcia-Manero G
. Natural history of newly diagnosed myelodysplastic syndrome with isolated inv(3)/t(3;3). Am J Hematol. 2020 12; 95(12):E326-E329.
PMID:
32886803
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
DiNardo CD
, Maiti A, Rausch CR,
Pemmaraju N
,
Naqvi K
,
Daver NG
,
Kadia TM
,
Borthakur G
,
Ohanian M
,
Alvarado Y
, Issa GC, Montalban-Bravo G, Short NJ, Yilmaz M,
Bose P
,
Jabbour EJ
,
Takahashi K
,
Burger JA
,
Garcia-Manero G
,
Jain N
,
Kornblau SM
, Thompson PA,
Estrov Z
, Masarova L, Sasaki K,
Verstovsek S
,
Ferrajoli A
, Weirda WG, Wang SA,
Konoplev S
, Chen Z, Pierce SA,
Ning J
, Qiao W, Ravandi F,
Andreeff M
, Welch JS,
Kantarjian HM
,
Konopleva MY
. 10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial. Lancet Haematol. 2020 Oct; 7(10):e724-e736.
PMID:
32896301
; PMCID:
PMC7549397
.
Citations:
62
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Lachowiez C, Bannon S,
Loghavi S
, Wang F, Kanagal-Shamanna R,
Mehta R
,
Daver N
,
Borthakur G
,
Pemmaraju N
, Ravandi F,
Patel KP
,
Garcia-Manero G
,
Takahashi K
,
Kantarjian H
,
Bhalla K
,
DiNardo CD
. Clonal evolution and treatment outcomes in hematopoietic neoplasms arising in patients with germline RUNX1 mutations. Am J Hematol. 2020 11; 95(11):E313-E315.
PMID:
32804409
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Saxena K,
DiNardo C
,
Daver N
,
Konopleva M
. Harnessing Apoptosis in AML. Clin Lymphoma Myeloma Leuk. 2020 09; 20 Suppl 1:S61-S64.
PMID:
32862872
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
, Price A,
Benton CB
, Patel K, Zhang W,
Konopleva M
,
Pemmaraju N
,
Takahashi K
,
Andreeff M
,
Borthakur G
. First Report of Sorafenib in Patients With Acute Myeloid Leukemia Harboring Non-Canonical FLT3 Mutations. Front Oncol. 2020; 10:1538.
PMID:
32984009
; PMCID:
PMC7479234
.
Citations:
1
Borthakur G
,
Zeng Z
,
Cortes JE
, Chen HC, Huang X,
Konopleva M
, Ravandi F,
Kadia T
,
Patel KP
,
Daver N
, Kelly MA, McQueen T, Wang RY,
Kantarjian H
,
Andreeff M
. Phase 1 study of combinatorial sorafenib, G-CSF, and plerixafor treatment in relapsed/refractory, FLT3-ITD-mutated acute myelogenous leukemia patients. Am J Hematol. 2020 11; 95(11):1296-1303.
PMID:
32697348
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Abaza Y,
Kantarjian H
, Alwash Y,
Borthakur G
,
Champlin R
,
Kadia T
,
Garcia-Manero G
,
Daver N
, Ravandi F,
Verstovsek S
,
Burger J
,
Estrov Z
,
Ohanian M
, Lim M,
Pemmaraju N
,
Jabbour E
, Cortes J. Phase I/II study of dasatinib in combination with decitabine in patients with accelerated or blast phase chronic myeloid leukemia. Am J Hematol. 2020 11; 95(11):1288-1295.
PMID:
32681739
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Major CK,
Kantarjian H
, Sasaki K,
Borthakur G
,
Kadia T
,
Pemmaraju N
,
DiNardo C
, Short NJ,
Daver N
,
Jabbour E
,
Champlin R
,
Garcia-Manero G
,
Konopleva M
,
Andreeff M
,
Kornblau S
,
Wierda W
, Pierce S, Ravandi F, Cortes J. Survivorship in AML - a landmark analysis on the outcomes of acute myelogenous leukemia patients after maintaining complete remission for at least 3 years. Leuk Lymphoma. 2020 12; 61(13):3120-3127.
PMID:
32755333
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Thakral B
,
Daver N
,
Tang Z
,
Patel KP
,
Ok CY
,
Loghavi S
,
Khoury JD
, Alotaibi AS,
Konopleva M
, Yilmaz M,
Medeiros LJ
. Clonal evolution with acquisition of BCR-ABL1 in refractory acute myeloid leukemia post therapy with FLT3-inhibitor. Leuk Lymphoma. 2020 12; 61(13):3243-3246.
PMID:
32696696
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Masarova L,
Bose P
,
Pemmaraju N
,
Daver NG
, Zhou L, Pierce S, Sasaki K,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Prognostic value of blasts in peripheral blood in myelofibrosis in the ruxolitinib era. Cancer. 2020 10 01; 126(19):4322-4331.
PMID:
32697338
; PMCID:
PMC7875207
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Paul S, Jammal N, Akhave N,
Aung PP
,
Loghavi S
,
Jain N
,
Garcia-Manero G
,
Borthakur G
,
Verstovsek S
,
Jabbour E
,
Adachi J
, Masarova L,
Daver N
, Ravandi F,
Pemmaraju N
. Atypical cases of necrotizing sweet syndrome in patients with myelodysplastic syndrome and acute myeloid leukaemia. Br J Haematol. 2020 10; 191(1):e10-e13.
PMID:
32686139
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Konopleva M
, Martinelli G,
Daver N
, Wei A, Higgins B, Ott M, Mascarenhas J,
Andreeff M
, Papayannidis C. MDM2 inhibition: an important step forward in cancer therapy. Leukemia. 2020 11; 34(11):2858-2874.
PMID:
32651541
.
Citations:
62
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Jabbour E
, Richard-Carpentier G, Sasaki Y,
Konopleva M
, Patel K, Roberts K, Gu Z, Wang F, Huang X, Sasaki K, Short NJ,
Jain N
, Ravandi F,
Daver NG
,
Kadia TM
,
Alvarado Y
,
DiNardo CD
, Issa GC,
Pemmaraju N
,
Garcia-Manero G
,
Verstovsek S
, Wang S,
Khoury JD
,
Jorgensen J
,
Champlin R
,
Khouri I
,
Kebriaei P
, Schroeder H, Khouri M, Mullighan CG,
Takahashi K
, O'Brien SM,
Kantarjian H
. Hyper-CVAD regimen in combination with ofatumumab as frontline therapy for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia: a single-arm, phase 2 trial. Lancet Haematol. 2020 Jul; 7(7):e523-e533.
PMID:
32589978
.
Citations:
10
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Shi Y, Peterson CB, Sahasrabhojane P, Gopalakrishnan V, Brumlow CE,
Daver NG
, Alfayez M, Boddu PC, Khan MAW,
Wargo JA
,
Do KA
, Jenq RR,
Kontoyiannis DP
,
Shelburne SA
, Galloway-Pe?a JR. Gut Microbiome Signatures Are Predictive of Infectious Risk Following Induction Therapy for Acute Myeloid Leukemia. Clin Infect Dis. 2020 06 24; 71(1):63-71.
PMID:
31436833
; PMCID:
PMC7312220
.
Citations:
27
Fields:
Com
Communicable Diseases
Translation:
Humans
Alfayez M, Issa GC,
Patel KP
, Wang F, Wang X, Short NJ,
Cortes JE
,
Kadia T
, Ravandi F, Pierce S, Assi R,
Garcia-Manero G
,
DiNardo CD
,
Daver N
,
Pemmaraju N
,
Kantarjian H
,
Borthakur G
. The Clinical impact of PTPN11 mutations in adults with acute myeloid leukemia. Leukemia. 2021 03; 35(3):691-700.
PMID:
32561839
.
Citations:
6
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Issa GC,
Kantarjian HM
, Xiao L,
Ning J
,
Alvarado Y
,
Borthakur G
,
Daver N
,
DiNardo CD
,
Jabbour E
,
Bose P
,
Jain N
,
Kadia TM
,
Naqvi K
,
Pemmaraju N
,
Takahashi K
,
Verstovsek S
, Andreeff M,
Kornblau SM
,
Estrov Z
,
Ferrajoli A
,
Garcia-Manero G
,
Ohanian M
,
Wierda WG
, Ravandi F,
Cortes JE
. Phase II trial of CPX-351 in patients with acute myeloid leukemia at high risk for induction mortality. Leukemia. 2020 11; 34(11):2914-2924.
PMID:
32546726
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ravandi F, Pierce S,
Garcia-Manero G
,
Kadia T
,
Jabbour E
,
Borthakur G
,
DiNardo CD
,
Daver N
, Short NJ,
Alvarado Y
, Cortes J, Kim C, Kelsh M, Katz A, Williams R, Yang Z, Mehta B,
Kantarjian H
. Salvage Therapy Outcomes in a Historical Cohort of Patients With Relapsed or Refractory Acute Myeloid Leukemia. Clin Lymphoma Myeloma Leuk. 2020 11; 20(11):e871-e882.
PMID:
32792304
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Short NJ, Richard-Carpentier G, Kanagal-Shamanna R,
Patel KP
,
Konopleva M
, Papageorgiou I,
Pemmaraju N
,
Borthakur G
, Ravandi F,
DiNardo CD
,
Kadia TM
,
Kantarjian H
, Lamba JK,
Daver N
. Impact of CD33 and ABCB1 single nucleotide polymorphisms in patients with acute myeloid leukemia and advanced myeloid malignancies treated with decitabine plus gemtuzumab ozogamicin. Am J Hematol. 2020 09; 95(9):E225-E228.
PMID:
32356320
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Paul S, Rausch CR,
Jain N
,
Kadia T
, Ravandi F,
DiNardo CD
, Welch MA,
Dabaja BS
,
Daver N
,
Garcia-Manero G
,
Wierda W
,
Pemmaraju N
, Montalban Bravo G, Thompson P,
Verstovsek S
,
Konopleva M
,
Kantarjian H
,
Jabbour E
. Treating Leukemia in the Time of COVID-19. Acta Haematol. 2021; 144(2):132-145.
PMID:
32392559
; PMCID:
PMC7270066
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
Cells
PH
Public Health
Samra B, Richard-Carpentier G,
Kadia TM
, Ravandi F,
Daver N
,
DiNardo CD
, Issa GC,
Bose P
,
Konopleva MY
, Yilmaz M,
Ohanian M
,
Borthakur G
,
Garcia-Manero G
, Pierce S,
Cortes JE
,
Kantarjian H
, Short NJ. Characteristics and outcomes of patients with therapy-related acute myeloid leukemia with normal karyotype. Blood Cancer J. 2020 05 04; 10(5):47.
PMID:
32366832
; PMCID:
PMC7198507
.
Citations:
2
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Abou Dalle I, Ghorab A, Patel K, Wang X, Hwang H, Cortes J, Issa GC, Yalniz F, Sasaki K, Chihara D, Price A,
Kadia T
,
Pemmaraju N
,
Daver N
,
DiNardo C
, Ravandi F,
Kantarjian HM
,
Borthakur G
. Impact of numerical variation, allele burden, mutation length and co-occurring mutations on the efficacy of tyrosine kinase inhibitors in newly diagnosed FLT3- mutant acute myeloid leukemia. Blood Cancer J. 2020 05 04; 10(5):48.
PMID:
32366841
; PMCID:
PMC7198530
.
Citations:
2
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Maiti A,
Kantarjian HM
, Popat V,
Borthakur G
,
Garcia-Manero G
,
Konopleva MY
,
DiNardo CD
,
Verstovsek S
,
Andreeff M
,
Kadia TM
, Ajufo HO, Goswamy RV, Blanco C, Velasquez M,
Daver NG
,
Pemmaraju N
, Pierce SR,
Wierda WG
,
Kornblau SM
, Ravandi F,
Cortes JE
. Clinical value of event-free survival in acute myeloid leukemia. Blood Adv. 2020 04 28; 4(8):1690-1699.
PMID:
32330243
; PMCID:
PMC7189295
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Sasaki K,
Kantarjian H
,
Wierda W
,
Ravandi-Kashani F
,
Jorgensen J
, Wang SA,
Khoury J
,
Daver N
,
Burger J
, Di Nardo CD,
Jain N
, Short NJ, Estrov Md Z, Konopleva Md PhD M, Ohanian DO M,
Garcia-Manero G
,
Kadia T
, Alvarado-Valero Y, Yilmaz M, Pierce S, Garris R, Ingram A, Cortes J, O'Brien S,
Jabbour E
. Phase 2 study of hyper-CMAD with liposomal vincristine for patients with newly diagnosed acute lymphoblastic leukemia. Am J Hematol. 2020 07; 95(7):734-739.
PMID:
32170867
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Lachowiez CA,
Loghavi S
,
Kadia TM
,
Daver N
,
Borthakur G
,
Pemmaraju N
,
Naqvi K
,
Alvarado Y
, Yilmaz M, Short N,
Ohanian M
, Pierce SR,
Patel KP
, Qiao W, Ning J, Sasaki K,
Takahashi K
,
Jabbour E
,
Andreeff M
, Ravandi F,
Kantarjian HM
,
Konopleva M
,
DiNardo CD
. Outcomes of older patients with NPM1-mutated AML: current treatments and the promise of venetoclax-based regimens. Blood Adv. 2020 04 14; 4(7):1311-1320.
PMID:
32251497
; PMCID:
PMC7160266
.
Citations:
38
Fields:
Hem
Hematology
Translation:
Humans
Maiti A, Franquiz MJ, Ravandi F,
Cortes JE
,
Jabbour EJ
, Sasaki K, Marx K,
Daver NG
,
Kadia TM
,
Konopleva MY
, Masarova L,
Borthakur G
,
DiNardo CD
,
Naqvi K
, Pierce S,
Kantarjian HM
, Short NJ. Venetoclax and BCR-ABL Tyrosine Kinase Inhibitor Combinations: Outcome in Patients with Philadelphia Chromosome-Positive Advanced Myeloid Leukemias. Acta Haematol. 2020; 143(6):567-573.
PMID:
32289808
; PMCID:
PMC7839068
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
Montalban-Bravo G, Kanagal-Shamanna R, Class CA, Sasaki K, Ravandi F,
Cortes JE
,
Daver N
,
Takahashi K
, Short NJ,
DiNardo CD
,
Jabbour E
,
Borthakur G
,
Naqvi K
, Issa GC,
Konopleva M
,
Khoury JD
,
Routbort M
, Pierce S,
Do KA
,
Bueso-Ramos C
, Patel K,
Kantarjian H
,
Garcia-Manero G
,
Kadia TM
. Outcomes of acute myeloid leukemia with myelodysplasia related changes depend on diagnostic criteria and therapy. Am J Hematol. 2020 06; 95(6):612-622.
PMID:
32112433
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Daver N
. A bispecific approach to improving CAR T cells in AML. Blood. 2020 03 05; 135(10):703-704.
PMID:
32135017
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Cells
Garcia-Manero G
,
Saliba RM
, Alfayez M,
Al-Atrash G
,
Ciurea SO
,
Jabbour EJ
,
Mehta RS
,
Popat UR
, Ravandi F,
Alousi AM
,
Kadia TM
,
Konopleva M
,
DiNardo CD
,
Rezvani K
,
Shpall EJ
,
Sharma P
,
Kantarjian HM
,
Champlin RE
,
Daver N
, Oran B. Posttransplantation cyclophosphamide improves transplantation outcomes in patients with AML/MDS who are treated with checkpoint inhibitors. Cancer. 2020 05 15; 126(10):2193-2205.
PMID:
32125707
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Bose P
,
Verstovsek S
,
Cortes JE
, Tse S, Gasior Y,
Jain N
,
Jabbour EJ
,
Estrov Z
,
Alvarado Y
,
DiNardo CD
,
Pemmaraju N
,
Kornblau SM
,
Kadia TM
,
Daver NG
,
Naqvi K
, Short NJ, Masarova L, Villareal J, Pierce SA, Nogueras-Gonzalez G, Huang X,
Garcia-Manero G
,
Kantarjian HM
, Ravandi F. A phase 1/2 study of ruxolitinib and decitabine in patients with post-myeloproliferative neoplasm acute myeloid leukemia. Leukemia. 2020 09; 34(9):2489-2492.
PMID:
32099037
.
Citations:
13
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Montalban-Bravo G, Kanagal-Shamanna R,
Benton CB
, Class CA, Chien KS, Sasaki K,
Naqvi K
,
Alvarado Y
,
Kadia TM
, Ravandi F,
Daver N
,
Takahashi K
,
Jabbour E
, Borthakur G,
Pemmaraju N
,
Konopleva M
, Soltysiak KA, Pierce SR,
Bueso-Ramos CE
,
Patel KP
,
Kantarjian H
,
Garcia-Manero G
. Genomic context and TP53 allele frequency define clinical outcomes in TP53-mutated myelodysplastic syndromes. Blood Adv. 2020 02 11; 4(3):482-495.
PMID:
32027746
; PMCID:
PMC7013259
.
Citations:
20
Fields:
Hem
Hematology
Translation:
Humans
Ciurea SO
, Kongtim P, Varma A,
Rondon G
, Chen J, Srour S,
Bashir Q
,
Alousi A
,
Mehta R
,
Oran B
,
Popat U
,
Hosing C
,
Olson A
,
Daver N
,
Konopleva M
,
Champlin RE
. Is there an optimal conditioning for older patients with AML receiving allogeneic hematopoietic cell transplantation? Blood. 2020 02 06; 135(6):449-452.
PMID:
31826244
; PMCID:
PMC8212356
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Short NJ,
Konopleva M
,
Kadia TM
,
Borthakur G
, Ravandi F,
DiNardo CD
,
Daver N
. Advances in the Treatment of Acute Myeloid Leukemia: New Drugs and New Challenges. Cancer Discov. 2020 04; 10(4):506-525.
PMID:
32014868
.
Citations:
71
Fields:
Neo
Neoplasms
Translation:
Humans
Pankow JD, Richard-Carpentier G,
Daver NG
, Glass WF, Kala J. Unique case of ANCA-negative pauci-immune necrotizing glomerulonephritis with diffuse alveolar hemorrhage, potentially associated with midostaurin. CEN Case Rep. 2020 05; 9(2):147-151.
PMID:
31955389
; PMCID:
PMC7148408
.
Citations:
Fields:
Nep
Nephrology
Translation:
Humans
Ye MT, Wang Y, Wang SA,
Pemmaraju N
,
Daver N
,
Verstovsek S
, Zhang Y,
Zuo Z
,
Medeiros LJ
, You MJ. Concurrent JAK2 V617F and MPL W515L in myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis. Leuk Lymphoma. 2020 04; 61(4):963-966.
PMID:
31750750
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Srour SA,
Saliba RM
, Bittencourt MCB, Perez JMR, Kongtim P,
Alousi A
,
Al-Atrash G
,
Olson A
, Betul O,
Mehta R
,
Popat U
,
Hosing C
,
Bashir Q
,
Khouri I
,
Kebriaei P
, Masarova L, Short N,
Jabbour E
,
Daver N
,
Konopleva M
, Ravandi F,
Kantarjian H
,
Champlin RE
,
Ciurea SO
. Haploidentical transplantation for acute myeloid leukemia patients with minimal/measurable residual disease at transplantation. Am J Hematol. 2019 12; 94(12):1382-1387.
PMID:
31595538
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Abbas HA, Alfayez M,
Kadia T
,
Ravandi-Kashani F
,
Daver N
. Midostaurin In Acute Myeloid Leukemia: An Evidence-Based Review And Patient Selection. Cancer Manag Res. 2019; 11:8817-8828.
PMID:
31632141
; PMCID:
PMC6782026
.
Citations:
7
Naing A
, Wong DJ, Infante JR, Korn WM, Aljumaily R, Papadopoulos KP, Autio KA,
Pant S
, Bauer TM, Drakaki A,
Daver NG
, Hung A, Ratti N, McCauley S, Van Vlasselaer P, Verma R, Ferry D, Oft M,
Diab A
, Garon EB,
Tannir NM
. Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial. Lancet Oncol. 2019 11; 20(11):1544-1555.
PMID:
31563517
; PMCID:
PMC8436252
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Alfayez M,
Kantarjian H
,
Kadia T
,
Ravandi-Kashani F
,
Daver N
. CPX-351 (vyxeos) in AML. Leuk Lymphoma. 2020 02; 61(2):288-297.
PMID:
31547736
.
Citations:
18
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ravandi F, Assi R,
Daver N
,
Benton CB
,
Kadia T
, Thompson PA,
Borthakur G
,
Alvarado Y
,
Jabbour EJ
,
Konopleva M
,
Takahashi K
,
Kornblau S
,
DiNardo CD
,
Estrov Z
, Flores W, Basu S,
Allison J
,
Sharma P
, Pierce S, Pike A,
Cortes JE
,
Garcia-Manero G
,
Kantarjian HM
. Idarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study. Lancet Haematol. 2019 Sep; 6(9):e480-e488.
PMID:
31400961
; PMCID:
PMC6778960
.
Citations:
31
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Sasaki K,
Kantarjian HM
,
Kadia T
, Patel K,
Loghavi S
,
Garcia-Manero G
,
Jabbour EJ
,
DiNardo C
,
Pemmaraju N
,
Daver N
, Dalle IA, Short N, Yilmaz M,
Bose P
,
Naqvi K
, Pierce S, Yalniz F,
Cortes JE
, Ravandi F. Sorafenib plus intensive chemotherapy improves survival in patients with newly diagnosed, FLT3-internal tandem duplication mutation-positive acute myeloid leukemia. Cancer. 2019 Nov 01; 125(21):3755-3766.
PMID:
31310323
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Yilmaz M,
Daver N
. From DNA Sequencing to Clinical Trials: Finding New Targeted Drugs for Acute Myeloid Leukemia. Drugs. 2019 Jul; 79(11):1177-1186.
PMID:
31222627
.
Citations:
2
Fields:
Dru
Drug Therapy
Pha
Pharmacology
Translation:
Humans
Cells
Rafei H,
Jabbour EJ
,
Kantarjian H
, Sinicrope KD, Kamiya-Matsuoka C,
Mehta RS
,
Daver NG
,
Kadia TM
,
Naqvi K
, Cortes J,
Konopleva M
. Neurotoxic events associated with BCR-ABL1 tyrosine kinase inhibitors: a case series. Leuk Lymphoma. 2019 12; 60(13):3292-3295.
PMID:
31246142
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Yalniz F, Abou Dalle I,
Kantarjian H
,
Borthakur G
,
Kadia T
, Patel K,
Loghavi S
,
Garcia-Manero G
, Sasaki K,
Daver N
,
DiNardo C
,
Pemmaraju N
, Short NJ, Yilmaz M,
Bose P
,
Naqvi K
, Pierce S,
Konopleva M
,
Andreeff M
, Cortes J, Ravandi F, Nogueras Gonz?lez GM. Prognostic significance of baseline FLT3-ITD mutant allele level in acute myeloid leukemia treated with intensive chemotherapy with/without sorafenib. Am J Hematol. 2019 09; 94(9):984-991.
PMID:
31237017
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Chamoun K,
Kantarjian HM
, Wang X,
Naqvi K
,
Aung F
,
Garcia-Manero G
,
Borthakur G
,
Jabbour E
,
Kadia T
,
Daver N
,
DiNardo CD
,
Jain N
,
Konopleva M
, Cortes J, Ravandi F, Yilmaz M. Unrecognized fluid overload during induction therapy increases morbidity in patients with acute promyelocytic leukemia. Cancer. 2019 09 15; 125(18):3219-3224.
PMID:
31150121
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
, Stein E. AML: The future is now or was it yesterday? Best Pract Res Clin Haematol. 2019 06; 32(2):115.
PMID:
31203992
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Boddu P, Jain P,
Borthakur G
,
Verstovsek S
,
Garcia-Manero G
,
Daver N
,
Kadia T
, Ravandi F,
Jabbour E
, Cortes J,
Kantarjian H
. Outcomes of patients with chronic phase chronic myeloid leukemia (CML-CP) after discontinuation of frontline ponatinib therapy. Leuk Lymphoma. 2019 12; 60(13):3172-3180.
PMID:
31125272
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Han L, Zhang Q, Dail M, Shi C, Cavazos A, Ruvolo VR, Zhao Y, Kim E, Rahmani M, Mak DH, Jin SS, Chen J, Phillips DC, Koller PB,
Jacamo R
,
Burks JK
,
DiNardo C
,
Daver N
,
Jabbour E
, Wang J,
Kantarjian HM
,
Andreeff M
, Grant S, Leverson JD, Sampath D,
Konopleva M
. Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models. Haematologica. 2020 03; 105(3):697-707.
PMID:
31123034
; PMCID:
PMC7049339
.
Citations:
30
Fields:
Hem
Hematology
Translation:
Humans
Cells
Strati P,
Takahashi K
, Peterson CB, Keating MJ, Thompson PA,
Daver NG
,
Jain N
,
Burger JA
,
Estrov Z
, O'Brien SM,
Kantarjian HM
,
Wierda WG
, Futreal PA,
Ferrajoli A
. Efficacy and predictors of response of lenalidomide and rituximab in patients with treatment-naive and relapsed CLL. Blood Adv. 2019 05 14; 3(9):1533-1539.
PMID:
31076409
; PMCID:
PMC6517659
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Medeiros BC, Chan SM,
Daver NG
, Jonas BA, Pollyea DA. Optimizing survival outcomes with post-remission therapy in acute myeloid leukemia. Am J Hematol. 2019 07; 94(7):803-811.
PMID:
30945331
; PMCID:
PMC6593671
.
Citations:
15
Fields:
Hem
Hematology
Translation:
Humans
Strati P,
Garcia-Manero G
, Zhao C,
Kadia T
,
Borthakur G
,
Konopleva M
,
Daver N
,
DiNardo CD
, Short NJ, Yilmaz M,
Naqvi K
,
Alvarado Y
, Pierce SA, Cortes J,
Bueso-Ramos C
,
Kantarjian H
, Ravandi F. Intensive chemotherapy is more effective than hypomethylating agents for the treatment of younger patients with myelodysplastic syndrome and elevated bone marrow blasts. Am J Hematol. 2019 07; 94(7):E188-E190.
PMID:
30977182
; PMCID:
PMC6566858
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Jabbour EJ
, Sasaki K, Ravandi F, Short NJ,
Garcia-Manero G
,
Daver N
,
Kadia T
,
Konopleva M
,
Jain N
, Cortes J, Issa GC, Jacob J, Kwari M, Thompson P, Garris R,
Pemmaraju N
, Yilmaz M, O'Brien SM,
Kantarjian HM
. Inotuzumab ozogamicin in combination with low-intensity chemotherapy (mini-HCVD) with or without blinatumomab versus standard intensive chemotherapy (HCVAD) as frontline therapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: A propensity score analysis. Cancer. 2019 08 01; 125(15):2579-2586.
PMID:
30985931
; PMCID:
PMC6625850
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Sasaki K,
Kantarjian HM
, O'Brien S, Ravandi F,
Konopleva M
,
Borthakur G
,
Garcia-Manero G
,
Wierda WG
,
Daver N
,
Ferrajoli A
,
Takahashi K
, Jain P, Rios MB, Pierce SA,
Jabbour EJ
,
Cortes JE
. Incidence of second malignancies in patients with chronic myeloid leukemia in the era of tyrosine kinase inhibitors. Int J Hematol. 2019 May; 109(5):545-552.
PMID:
30830579
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Short NJ,
Kantarjian H
, Ravandi F,
Daver N
. Emerging treatment paradigms with FLT3 inhibitors in acute myeloid leukemia. Ther Adv Hematol. 2019; 10:2040620719827310.
PMID:
30800259
; PMCID:
PMC6378516
.
Citations:
32
Alfayez M,
Ivan D
,
Pemmaraju N
,
Daver N
,
DiNardo CD
. Systemic Immunotherapy Effective for Refractory Extramedullary Acute Myeloid Leukemia. JCO Precis Oncol. 2019; 3.
PMID:
30957058
; PMCID:
PMC6448807
.
Citations:
Fields:
Neo
Neoplasms
Kantarjian HM
,
Jabbour EJ
,
Garcia-Manero G
,
Kadia TM
,
DiNardo CD
,
Daver NG
,
Borthakur G
,
Jain N
, Waukau JB, Kwari MI, Ravandi F, Anderson BD, Iizuka K, Jin C, Zhang C, Plunkett WK. Phase 1/2 study of DFP-10917 administered by continuous intravenous infusion in patients with recurrent or refractory acute myeloid leukemia. Cancer. 2019 05 15; 125(10):1665-1673.
PMID:
30668890
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Daver N
. The Emerging Profile of Immunotherapy Approaches in the Treatment of AML. Oncology (Williston Park). 2019 Jan 17; 33(1):28-32.
PMID:
30731016
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
, Schlenk RF, Russell NH, Levis MJ. Targeting FLT3 mutations in AML: review of current knowledge and evidence. Leukemia. 2019 02; 33(2):299-312.
PMID:
30651634
; PMCID:
PMC6365380
.
Citations:
218
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Bose P
, Swaminathan M,
Pemmaraju N
,
Ferrajoli A
,
Jabbour EJ
,
Daver NG
,
DiNardo CD
,
Alvarado Y
, Yilmaz M, Huynh-Lu J, Qiao W, Wang X, Matamoros A, Zhou L, Pierce S, Schroeder KD,
Kantarjian HM
,
Verstovsek S
. A phase 2 study of pracinostat combined with ruxolitinib in patients with myelofibrosis. Leuk Lymphoma. 2019 07; 60(7):1767-1774.
PMID:
30632841
; PMCID:
PMC6594864
.
Citations:
8
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Chamoun K,
Kantarjian H
, Atallah R, Gonzalez GN, Issa GC, Rios MB,
Garcia-Manero G
,
Borthakur G
, Ravandi F,
Jain N
,
Daver N
,
Konopleva M
,
DiNardo CD
,
Kadia T
,
Pemmaraju N
,
Jabbour E
, Cortes J. Tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: a single-institution experience. J Hematol Oncol. 2019 01 03; 12(1):1.
PMID:
30606227
; PMCID:
PMC6318861
.
Citations:
9
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Shroff GS
,
Truong MT
,
Carter BW
,
Benveniste MF
, Kanagal-Shamanna R, Rauch G,
Viswanathan C
, Boddu PC,
Daver N
,
Wu CC
. Leukemic Involvement in the Thorax. Radiographics. 2019 Jan-Feb; 39(1):44-61.
PMID:
30620703
.
Citations:
5
Fields:
Rad
Radiology
Translation:
Humans
Maiti A,
Naqvi K
,
Kadia TM
,
Borthakur G
,
Takahashi K
,
Bose P
,
Daver NG
, Patel A,
Alvarado Y
,
Ohanian M
,
DiNardo CD
,
Cortes JE
,
Jabbour EJ
,
Garcia-Manero G
,
Kantarjian HM
, Ravandi F. Phase II Trial of MEK Inhibitor Binimetinib (MEK162) in RAS-mutant Acute Myeloid Leukemia. Clin Lymphoma Myeloma Leuk. 2019 03; 19(3):142-148.e1.
PMID:
30635233
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Short NJ,
Kantarjian HM
,
Loghavi S
, Huang X, Qiao W,
Borthakur G
,
Kadia TM
,
Daver N
,
Ohanian M
,
Dinardo CD
,
Estrov Z
, Kanagal-Shamanna R, Maiti A,
Benton CB
,
Bose P
,
Alvarado Y
,
Jabbour E
,
Kornblau SM
,
Pemmaraju N
,
Jain N
, Gasior Y, Richie MA, Pierce S, Cortes J,
Konopleva M
,
Garcia-Manero G
, Ravandi F. Treatment with a 5-day versus a 10-day schedule of decitabine in older patients with newly diagnosed acute myeloid leukaemia: a randomised phase 2 trial. Lancet Haematol. 2019 Jan; 6(1):e29-e37.
PMID:
30545576
; PMCID:
PMC6563344
.
Citations:
32
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Boddu PC,
Kadia TM
,
Garcia-Manero G
, Cortes J, Alfayez M,
Borthakur G
,
Konopleva M
,
Jabbour EJ
,
Daver NG
,
DiNardo CD
,
Naqvi K
, Yilmaz M, Short NJ, Pierce S,
Kantarjian HM
, Ravandi F. Validation of the 2017 European LeukemiaNet classification for acute myeloid leukemia with NPM1 and FLT3-internal tandem duplication genotypes. Cancer. 2019 04 01; 125(7):1091-1100.
PMID:
30521114
; PMCID:
PMC6561101
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Benton CB
, Chien KS, Tefferi A, Rodriguez J, Ravandi F,
Daver N
,
Jabbour E
,
Jain N
,
Alvarado Y
, Kwari M, Pierce S, Maiti A, Hornbaker M, Santos MA, Martinez S, Siguero M, Zblewski D, Al-Kali A, Hogan WJ,
Kantarjian H
, Pardanani A,
Garcia-Manero G
. Safety and tolerability of lurbinectedin (PM01183) in patients with acute myeloid leukemia and myelodysplastic syndrome. Hematol Oncol. 2019 Feb; 37(1):96-102.
PMID:
30153704
; PMCID:
PMC6386594
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Jabbour E
, Short NJ, Ravandi F, Huang X,
Daver N
,
DiNardo CD
,
Konopleva M
,
Pemmaraju N
,
Wierda W
,
Garcia-Manero G
, Sasaki K, Cortes J, Garris R,
Khoury JD
,
Jorgensen J
,
Jain N
, Alvarez J, O'Brien S,
Kantarjian H
. Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: long-term follow-up of a single-centre, phase 2 study. Lancet Haematol. 2018 Dec; 5(12):e618-e627.
PMID:
30501869
; PMCID:
PMC10020885
.
Citations:
50
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Williams P, Basu S,
Garcia-Manero G
, Hourigan CS, Oetjen KA,
Cortes JE
, Ravandi F,
Jabbour EJ
, Al-Hamal Z,
Konopleva M
,
Ning J
, Xiao L, Hidalgo Lopez J,
Kornblau SM
,
Andreeff M
, Flores W,
Bueso-Ramos C
, Blando J, Galera P, Calvo KR,
Al-Atrash G
,
Allison JP
,
Kantarjian HM
,
Sharma P
,
Daver NG
. The distribution of T-cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia. Cancer. 2019 05 01; 125(9):1470-1481.
PMID:
30500073
; PMCID:
PMC6467779
.
Citations:
84
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Oran B
,
Daver N
. Check-Point Inhibitors before and after Allogeneic Hematopoietic Stem Cell Transplant: The Double-Edge Sword. Biol Blood Marrow Transplant. 2019 01; 25(1):e1-e2.
PMID:
30500441
.
Citations:
2
Fields:
Hem
Hematology
Tra
Transplantation
Translation:
Humans
Daver N
,
Garcia-Manero G
, Basu S, Boddu PC, Alfayez M,
Cortes JE
,
Konopleva M
,
Ravandi-Kashani F
,
Jabbour E
,
Kadia T
, Nogueras-Gonzalez GM,
Ning J
,
Pemmaraju N
,
DiNardo CD
,
Andreeff M
, Pierce SA, Gordon T,
Kornblau SM
, Flores W, Alhamal Z,
Bueso-Ramos C
,
Jorgensen JL
,
Patel KP
, Blando J,
Allison JP
,
Sharma P
,
Kantarjian H
. Efficacy, Safety, and Biomarkers of Response to Azacitidine and Nivolumab in Relapsed/Refractory Acute Myeloid Leukemia: A Nonrandomized, Open-Label, Phase II Study. Cancer Discov. 2019 03; 9(3):370-383.
PMID:
30409776
; PMCID:
PMC6397669
.
Citations:
151
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Angelova E, Audette C, Kovtun Y,
Daver N
, Wang SA, Pierce S,
Konoplev SN
, Khogeer H,
Jorgensen JL
,
Konopleva M
, Zweidler-McKay PA,
Medeiros LJ
,
Kantarjian HM
,
Jabbour EJ
,
Khoury JD
. CD123 expression patterns and selective targeting with a CD123-targeted antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia. Haematologica. 2019 04; 104(4):749-755.
PMID:
30361418
; PMCID:
PMC6442980
.
Citations:
22
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Assi R,
Garcia-Manero G
, Ravandi F,
Borthakur G
,
Daver NG
,
Jabbour E
,
Burger J
,
Estrov Z
,
Dinardo CD
,
Alvarado Y
, Hendrickson S,
Ferrajoli A
,
Wierda W
, Cortes J,
Kantarjian H
,
Kadia TM
. Addition of eltrombopag to immunosuppressive therapy in patients with newly diagnosed aplastic anemia. Cancer. 2018 11 01; 124(21):4192-4201.
PMID:
30307606
; PMCID:
PMC6800043
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Assi R, Gur HD,
Loghavi S
,
Konoplev SN
,
Konopleva M
,
Daver N
, Tashakori M,
Kadia T
,
Routbort M
, Salem A, Kanagal-Shamanna R, Quesada A,
Jabbour EJ
,
Kornblau SM
,
Medeiros LJ
,
Kantarjian H
,
Khoury JD
. P53 protein overexpression in de novo acute myeloid leukemia patients with normal diploid karyotype correlates with FLT3 internal tandem duplication and worse relapse-free survival. Am J Hematol. 2018 11; 93(11):1376-1383.
PMID:
30117185
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Bose P
, Nazha A, Komrokji RS,
Patel KP
, Pierce SA, Al-Ali N, Sochacki A, Shaver A, Ma W,
Su X
,
Daver NG
,
DiNardo CD
,
Garcia-Manero G
,
Loghavi S
,
Bueso-Ramos C
,
Kantarjian HM
, Sekeres MA, Savona MR, Maciejewski JP,
Verstovsek S
. Mutational landscape of myelodysplastic/myeloproliferative neoplasm-unclassifiable. Blood. 2018 11 08; 132(19):2100-2103.
PMID:
30242087
; PMCID:
PMC6236463
.
Citations:
17
Fields:
Hem
Hematology
Translation:
Humans
Masarova L,
Verstovsek S
, Hidalgo-Lopez JE,
Pemmaraju N
,
Bose P
,
Estrov Z
,
Jabbour EJ
,
Ravandi-Kashani F
,
Takahashi K
,
Cortes JE
, Ning J,
Ohanian M
,
Alvarado Y
, Zhou L, Pierce S, Gergis R,
Patel KP
,
Luthra R
,
Kadia TM
,
DiNardo CD
,
Borthakur G
,
Bhalla K
,
Garcia-Manero G
,
Bueso-Ramos CE
,
Kantarjian HM
,
Daver N
. A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis. Blood. 2018 10 18; 132(16):1664-1674.
PMID:
30185431
; PMCID:
PMC6265645
.
Citations:
28
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Ohanian M
,
Garcia-Manero G
, Levis M,
Jabbour E
,
Daver N
,
Borthakur G
,
Kadia T
, Pierce S,
Burger J
, Richie MA, Patel K,
Andreeff M
,
Estrov Z
, Cortes J,
Kantarjian H
, Ravandi F. Sorafenib Combined with 5-azacytidine in Older Patients with Untreated FLT3-ITD Mutated Acute Myeloid Leukemia. Am J Hematol. 2018 09; 93(9):1136-1141.
PMID:
30028037
.
Citations:
30
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kadia TM
, Cortes J, Ravandi F,
Jabbour E
,
Konopleva M
,
Benton CB
,
Burger J
, Sasaki K,
Borthakur G
,
DiNardo CD
,
Pemmaraju N
,
Daver N
,
Ferrajoli A
, Wang X, Patel K,
Jorgensen JL
, Wang S, O'Brien S, Pierce S, Tuttle C,
Estrov Z
,
Verstovsek S
,
Garcia-Manero G
,
Kantarjian H
. Cladribine and low-dose cytarabine alternating with decitabine as front-line therapy for elderly patients with acute myeloid leukaemia: a phase 2 single-arm trial. Lancet Haematol. 2018 Sep; 5(9):e411-e421.
PMID:
30115541
; PMCID:
PMC6775639
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Wiese M,
Daver N
. Unmet clinical needs and economic burden of disease in the treatment landscape of acute myeloid leukemia. Am J Manag Care. 2018 08; 24(16 Suppl):S347-S355.
PMID:
30132678
.
Citations:
13
Fields:
Hea
Health Services
Translation:
Humans
Lyle L,
Daver N
. Current and emerging therapies for patients with acute myeloid leukemia: a focus on MCL-1 and the CDK9 pathway. Am J Manag Care. 2018 08; 24(16 Suppl):S356-S365.
PMID:
30132679
.
Citations:
12
Fields:
Hea
Health Services
Translation:
Humans
Yalniz FF,
Daver N
, Rezvani K,
Kornblau S
,
Ohanian M
,
Borthakur G
,
DiNardo CD
,
Konopleva M
, Burger J, Gasior Y, Pierce S,
Kantarjian H
,
Garcia-Manero G
. A Pilot Trial of Lirilumab With or Without Azacitidine for Patients With Myelodysplastic Syndrome. Clin Lymphoma Myeloma Leuk. 2018 10; 18(10):658-663.e2.
PMID:
30001986
; PMCID:
PMC6750214
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Molina JR, Sun Y, Protopopova M, Gera S, Bandi M, Bristow C, McAfoos T, Morlacchi P, Ackroyd J, Agip AA,
Al-Atrash G
, Asara J, Bardenhagen J, Carrillo CC, Carroll C,
Chang E
,
Ciurea S
, Cross JB, Czako B, Deem A,
Daver N
,
de Groot JF
, Dong JW, Feng N, Gao G, Gay J, Do MG, Greer J, Giuliani V, Han J, Han L, Henry VK, Hirst J, Huang S, Jiang Y, Kang Z, Khor T,
Konoplev S
, Lin YH, Liu G, Lodi A, Lofton T, Ma H, Mahendra M, Matre P, Mullinax R, Peoples M, Petrocchi A, Rodriguez-Canale J, Serreli R, Shi T, Smith M, Tabe Y, Theroff J, Tiziani S, Xu Q, Zhang Q,
Muller F
,
DePinho RA
, Toniatti C,
Draetta GF
, Heffernan TP,
Konopleva M
, Jones P, Di Francesco ME, Marszalek JR. An inhibitor of oxidative phosphorylation exploits cancer vulnerability. Nat Med. 2018 07; 24(7):1036-1046.
PMID:
29892070
.
Citations:
261
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Chyla B,
Daver N
, Doyle K, McKeegan E, Huang X, Ruvolo V, Wang Z, Chen K, Souers A, Leverson J, Potluri J, Boghaert E, Bhathena A,
Konopleva M
, Popovic R. Genetic Biomarkers Of Sensitivity and Resistance to Venetoclax Monotherapy in Patients With Relapsed Acute Myeloid Leukemia. Am J Hematol. 2018 May 17.
PMID:
29770480
; PMCID:
PMC6120451
.
Citations:
53
Fields:
Hem
Hematology
Zhang W, Ly C, Ishizawa J, Mu H, Ruvolo V, Shacham S,
Daver N
,
Andreeff M
. Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in FLT3-mutated acute myeloid leukemias: from concept to clinical trial. Haematologica. 2018 10; 103(10):1642-1653.
PMID:
29773601
; PMCID:
PMC6165819
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
CT
Clinical Trials
Morita K,
Kantarjian HM
, Wang F, Yan Y,
Bueso-Ramos C
, Sasaki K, Issa GC, Wang S,
Jorgensen J
, Song X, Zhang J, Tippen S, Thornton R, Coyle M, Little L, Gumbs C,
Pemmaraju N
,
Daver N
,
DiNardo CD
,
Konopleva M
,
Andreeff M
, Ravandi F,
Cortes JE
,
Kadia T
,
Jabbour E
,
Garcia-Manero G
,
Patel KP
, Futreal PA,
Takahashi K
. Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia. J Clin Oncol. 2018 06 20; 36(18):1788-1797.
PMID:
29702001
; PMCID:
PMC6008108
.
Citations:
66
Fields:
Neo
Neoplasms
Translation:
Humans
Thompson PA, Peterson CB, Strati P,
Jorgensen J
, Keating MJ, O'Brien SM,
Ferrajoli A
,
Burger JA
,
Estrov Z
,
Jain N
,
Kadia TM
,
Borthakur G
,
DiNardo CD
,
Daver N
,
Jabbour E
,
Wierda WG
. Serial minimal residual disease (MRD) monitoring during first-line FCR treatment for CLL may direct individualized therapeutic strategies. Leukemia. 2018 11; 32(11):2388-2398.
PMID:
29769624
; PMCID:
PMC6192870
.
Citations:
12
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Assi R,
Kantarjian HM
,
Kadia TM
,
Pemmaraju N
,
Jabbour E
,
Jain N
,
Daver N
,
Estrov Z
, Uehara T, Owa T,
Cortes JE
,
Borthakur G
. Final results of a phase 2, open-label study of indisulam, idarubicin, and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome. Cancer. 2018 07 01; 124(13):2758-2765.
PMID:
29660836
; PMCID:
PMC6800041
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ruvolo PP
, Ruvolo VR,
Burks JK
, Qiu Y, Wang RY,
Shpall EJ
, Mirandola L, Hail N,
Zeng Z
, McQueen T,
Daver N
,
Post SM
, Chiriva-Internati M,
Kornblau SM
,
Andreeff M
. Role of MSC-derived galectin 3 in the AML microenvironment. Biochim Biophys Acta Mol Cell Res. 2018 07; 1865(7):959-969.
PMID:
29655803
; PMCID:
PMC5936474
.
Citations:
6
Fields:
Bio
Biochemistry
Bio
Biophysics
Cel
Cell Biology
Translation:
Humans
Cells
Kantarjian HM
,
DiNardo CD
, Nogueras-Gonzalez GM,
Kadia TM
,
Jabbour E
,
Bueso-Ramos CE
, O'Brien SM,
Konopleva M
,
Jain NB
,
Daver NG
,
Shpall EJ
,
Champlin RE
, Simkins A,
Garcia-Manero G
, Keating MJ, Huang X,
Cortes JE
, Pierce SA, Ravandi F, Freireich EJ. Results of second salvage therapy in 673 adults with acute myelogenous leukemia treated at a single institution since 2000. Cancer. 2018 06 15; 124(12):2534-2540.
PMID:
29645075
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Assi R,
Kantarjian H
, Ravandi F,
Daver N
. Immune therapies in acute myeloid leukemia: a focus on monoclonal antibodies and immune checkpoint inhibitors. Curr Opin Hematol. 2018 03; 25(2):136-145.
PMID:
29206680
.
Citations:
26
Fields:
Hem
Hematology
Translation:
Humans
Daver N
, Boddu P,
Garcia-Manero G
, Yadav SS,
Sharma P
,
Allison J
,
Kantarjian H
. Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes. Leukemia. 2018 05; 32(5):1094-1105.
PMID:
29487386
; PMCID:
PMC6916728
.
Citations:
66
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Neelapu SS
,
Tummala S
,
Kebriaei P
,
Wierda W
, Locke FL, Lin Y,
Jain N
,
Daver N
, Gulbis AM, Adkins S, Rezvani K,
Hwu P
,
Shpall EJ
. Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'. Nat Rev Clin Oncol. 2018 04; 15(4):218.
PMID:
29434334
; PMCID:
PMC6716606
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Masarova L, Alhuraiji A,
Bose P
,
Daver N
,
Pemmaraju N
, Cortes J, Pierce S,
Kantarjian H
,
Verstovsek S
. Significance of thrombocytopenia in patients with primary and postessential thrombocythemia/polycythemia vera myelofibrosis. Eur J Haematol. 2018 Mar; 100(3):257-263.
PMID:
29226426
; PMCID:
PMC5814342
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Boddu P,
Kantarjian H
, Ravandi F,
Garcia-Manero G
,
Borthakur G
,
Andreeff M
,
Jabbour EJ
,
Benton CB
,
DiNardo CD
,
Konopleva M
,
Daver N
, Patel K,
Takahashi K
, Kanagal-Shamanna R, Cortes J,
Kadia T
. Outcomes with lower intensity therapy in TP53-mutated acute myeloid leukemia. Leuk Lymphoma. 2018 09; 59(9):2238-2241.
PMID:
29338567
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Kantarjian H
, Ravandi F, Short NJ, Huang X,
Jain N
, Sasaki K,
Daver N
,
Pemmaraju N
,
Khoury JD
,
Jorgensen J
,
Alvarado Y
,
Konopleva M
,
Garcia-Manero G
,
Kadia T
, Yilmaz M, Bortakhur G,
Burger J
,
Kornblau S
,
Wierda W
,
DiNardo C
,
Ferrajoli A
, Jacob J, Garris R, O'Brien S,
Jabbour E
. Inotuzumab ozogamicin in combination with low-intensity chemotherapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukaemia: a single-arm, phase 2 study. Lancet Oncol. 2018 02; 19(2):240-248.
PMID:
29352703
.
Citations:
58
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Montalban-Bravo G,
Takahashi K
, Patel K, Wang F, Xingzhi S, Nogueras GM, Huang X, Pierola AA,
Jabbour E
,
Colla S
, Borthakur G,
Daver N
,
Estrov Z
,
Kadia T
,
Pemmaraju N
, Ravandi F,
Bueso-Ramos C
, Chamseddine A,
Konopleva M
, Zhang J,
Kantarjian H
,
Futreal A
,
Garcia-Manero G
, Ga?an-Gomez I. Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms. Oncotarget. 2018 Feb 09; 9(11):9714-9727.
PMID:
29515765
; PMCID:
PMC5839396
.
Citations:
23
Fields:
Neo
Neoplasms
Masarova L,
Kantarjian H
, Ravandi F,
Sharma P
,
Garcia-Manero G
,
Daver N
. Update on Immunotherapy in AML and MDS: Monoclonal Antibodies and Checkpoint Inhibitors Paving the Road for Clinical Practice. Adv Exp Med Biol. 2018; 995:97-116.
PMID:
30539507
.
Citations:
8
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
DiNardo CD
, Rausch CR, Benton C,
Kadia T
,
Jain N
,
Pemmaraju N
,
Daver N
, Covert W, Marx KR, Mace M,
Jabbour E
, Cortes J,
Garcia-Manero G
, Ravandi F,
Bhalla KN
,
Kantarjian H
,
Konopleva M
. Clinical experience with the BCL2-inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies. Am J Hematol. 2018 03; 93(3):401-407.
PMID:
29218851
.
Citations:
126
Fields:
Hem
Hematology
Translation:
Humans
Cells
Jabbour E
, Yilmaz M,
Khoury JD
, Ravandi F,
Jain N
,
Garcia-Manero G
,
Konopleva M
, Short NJ, Thompson PA,
Wierda W
,
Daver N
, Cortes J, O'brien S,
Kantarjian H
, D?ll J, Einsele H, Topp MS. Outcome of patients with relapsed/refractory acute lymphoblastic leukemia after blinatumomab failure: No change in the level of CD19 expression. Am J Hematol. 2018 03; 93(3):371-374.
PMID:
29178361
.
Citations:
37
Fields:
Hem
Hematology
Translation:
Humans
Cells
Sasaki K,
Kantarjian H
, O'Brien S, Ravandi F,
Konopleva M
,
Borthakur G
,
Garcia-Manero G
,
Wierda W
,
Daver N
,
Ferrajoli A
,
Takahashi K
, Jain P, Rios MB, Pierce S,
Jabbour E
,
Cortes JE
. Prediction for sustained deep molecular response of BCR-ABL1 levels in patients with chronic myeloid leukemia in chronic phase. Cancer. 2018 03 15; 124(6):1160-1168.
PMID:
29266206
; PMCID:
PMC5851790
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Roboz GJ,
Kantarjian HM
, Yee KWL, Kropf PL, O'Connell CL, Griffiths EA, Stock W,
Daver NG
,
Jabbour E
, Ritchie EK, Walsh KJ, Rizzieri D, Lunin SD, Curio T, Chung W, Hao Y, Lowder JN, Azab M, Issa JJ. Dose, schedule, safety, and efficacy of guadecitabine in relapsed or refractory acute myeloid leukemia. Cancer. 2018 01 15; 124(2):325-334.
PMID:
29211308
; PMCID:
PMC5814873
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Daver N
,
Kontoyiannis DP
. Checkpoint inhibitors and aspergillosis in AML: the double hit hypothesis. Lancet Oncol. 2017 12; 18(12):1571-1573.
PMID:
29208429
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Assi R,
Kantarjian HM
,
Garcia-Manero G
,
Cortes JE
,
Pemmaraju N
, Wang X, Nogueras-Gonzalez G,
Jabbour E
,
Bose P
,
Kadia T
,
Dinardo CD
, Patel K,
Bueso-Ramos C
, Zhou L, Pierce S, Gergis R, Tuttle C,
Borthakur G
,
Estrov Z
,
Luthra R
, Hidalgo-Lopez J,
Verstovsek S
,
Daver N
. A phase II trial of ruxolitinib in combination with azacytidine in myelodysplastic syndrome/myeloproliferative neoplasms. Am J Hematol. 2018 02; 93(2):277-285.
PMID:
29134664
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Alhuraiji A,
Kantarjian H
, Boddu P, Ravandi F,
Borthakur G
,
DiNardo C
,
Daver N
,
Kadia T
,
Pemmaraju N
, Pierce S,
Garcia-Manero G
,
Wierda W
,
Verstovsek S
,
Jabbour E
, Cortes J. Prognostic significance of additional chromosomal abnormalities at the time of diagnosis in patients with chronic myeloid leukemia treated with frontline tyrosine kinase inhibitors. Am J Hematol. 2018 01; 93(1):84-90.
PMID:
29027261
.
Citations:
14
Fields:
Hem
Hematology
Translation:
Humans
Strati P, Tang G, Duose DY,
Mallampati S
,
Luthra R
,
Patel KP
, Hussaini M, Mirza AS, Komrokji RS, Oh S, Mascarenhas J, Najfeld V,
Subbiah V
,
Kantarjian H
,
Garcia-Manero G
,
Verstovsek S
,
Daver N
. Myeloid/lymphoid neoplasms with FGFR1 rearrangement. Leuk Lymphoma. 2018 07; 59(7):1672-1676.
PMID:
29119847
.
Citations:
12
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Abaza Y, M Kantarjian H, Faderl S,
Jabbour E
,
Jain N
, Thomas D,
Kadia T
,
Borthakur G
, D Khoury J,
Burger J
,
Wierda W
, O'Brien S,
Konopleva M
,
Ferrajoli A
,
Kebriaei P
,
Dabaja B
,
Kornblau S
,
Alvarado Y
,
Daver N
,
Pemmaraju N
,
Bose P
, Thompson P, Al Azzawi H, Kelly M, Garris R, Jain P,
Garcia-Manero G
, Cortes J, Ravandi F. Hyper-CVAD plus nelarabine in newly diagnosed adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma. Am J Hematol. 2018 01; 93(1):91-99.
PMID:
29047158
.
Citations:
21
Fields:
Hem
Hematology
Translation:
Humans
Wang W,
Routbort MJ
,
Tang Z
,
Ok CY
,
Patel KP
,
Daver N
,
Garcia-Manero G
,
Medeiros LJ
, Wang SA. Characterization of TP53 mutations in low-grade myelodysplastic syndromes and myelodysplastic syndromes with a non-complex karyotype. Eur J Haematol. 2017 Dec; 99(6):536-543.
PMID:
28926144
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Boddu P, Shah AR,
Borthakur G
,
Verstovsek S
,
Garcia-Manero G
,
Daver N
,
Kadia T
, Ravandi F,
Jain N
, Alhuraiji A,
Burger J
,
Kornblau S
, Pierce S, Dellasala S,
Jabbour E
,
Kantarjian H
, Cortes J. Life after ponatinib failure: outcomes of chronic and accelerated phase CML patients who discontinued ponatinib in the salvage setting. Leuk Lymphoma. 2018 06; 59(6):1312-1322.
PMID:
28972430
; PMCID:
PMC6120342
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Boddu P, Oviedo SP, Rausch CR, Yam C,
Daver N
,
Kantarjian H
,
Kadia TM
. PET-CT in AML-related hemophagocytic lymphohistiocytosis. Leuk Lymphoma. 2018 06; 59(6):1486-1489.
PMID:
28958191
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Boddu P,
Garcia-Manero G
, Ravandi F,
Borthakur G
,
Jabbour E
,
DiNardo C
,
Jain N
,
Daver N
,
Pemmaraju N
,
Anderlini P
,
Parmar S
, Kc D, Akosile M, Pierce SA,
Champlin R
, Cortes J,
Kantarjian H
,
Kadia T
. Clinical outcomes in adult patients with aplastic anemia: A single institution experience. Am J Hematol. 2017 Dec; 92(12):1295-1302.
PMID:
28850699
; PMCID:
PMC5987765
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Neelapu SS
,
Tummala S
,
Kebriaei P
,
Wierda W
,
Gutierrez C
, Locke FL, Komanduri KV, Lin Y,
Jain N
,
Daver N
,
Westin J
, Gulbis AM,
Loghin ME
,
de Groot JF
, Adkins S, Davis SE, Rezvani K,
Hwu P
,
Shpall EJ
. Chimeric antigen receptor T-cell therapy - assessment and management of toxicities. Nat Rev Clin Oncol. 2018 Jan; 15(1):47-62.
PMID:
28925994
; PMCID:
PMC6733403
.
Citations:
631
Fields:
Neo
Neoplasms
Translation:
Humans
Ciurea SO
, Shah MV,
Saliba RM
, Gaballa S, Kongtim P,
Rondon G
, Chen J, Wallis W,
Cao K
,
Konopleva M
,
Daver N
, Cortes J, Ravandi F,
Alousi A
, Ahmed S,
Popat U
,
Parmar S
,
Bashir Q
, Betul O,
Hosing C
,
Shpall EJ
, Rezvani K,
Khouri IF
,
Kebriaei P
,
Champlin RE
. Haploidentical Transplantation for Older Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome. Biol Blood Marrow Transplant. 2018 06; 24(6):1232-1236.
PMID:
28918304
; PMCID:
PMC7172017
.
Citations:
23
Fields:
Hem
Hematology
Tra
Transplantation
Translation:
Humans
Jain N
, Lu X,
Daver N
,
Thakral B
, Wang SA,
Konoplev S
, Patel K, Kanagal-Shamanna R, Valentine M, Tang G,
Pemmaraju N
,
Jorgensen J
,
Kebriaei P
,
Nunez CA
,
Wierda W
,
Jabbour E
, Roberts KG, Mullighan CG,
Kantarjian H
,
Konopleva M
. Co-occurrence of CRLF2-rearranged and Ph+ acute lymphoblastic leukemia: a report of four patients. Haematologica. 2017 12; 102(12):e514-e517.
PMID:
28860345
; PMCID:
PMC5709127
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Cells
Boddu P,
Kantarjian H
,
Garcia-Manero G
, Ravandi F,
Jabbour E
,
Borthakur G
,
Daver N
,
Pemmaraju N
, Pierce S, Cortes J,
Kadia TM
. Time to response and survival in hypomethylating agent-treated acute myeloid leukemia. Leuk Lymphoma. 2018 04; 59(4):1012-1015.
PMID:
28838278
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Masarova L,
Verstovsek S
,
Kantarjian H
,
Daver N
. Immunotherapy based approaches in myelofibrosis. Expert Rev Hematol. 2017 10; 10(10):903-914.
PMID:
28799436
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
Assi R,
Kantarjian H
, Short NJ,
Daver N
,
Takahashi K
,
Garcia-Manero G
,
DiNardo C
,
Burger J
, Cortes J,
Jain N
,
Wierda W
, Chamoun S,
Konopleva M
,
Jabbour E
. Safety and Efficacy of Blinatumomab in Combination With a Tyrosine Kinase Inhibitor for the Treatment of Relapsed Philadelphia Chromosome-positive Leukemia. Clin Lymphoma Myeloma Leuk. 2017 Dec; 17(12):897-901.
PMID:
28927784
.
Citations:
45
Fields:
Neo
Neoplasms
Translation:
Humans
Boddu P,
Kantarjian H
,
Borthakur G
,
Kadia T
,
Daver N
, Pierce S,
Andreeff M
, Ravandi F, Cortes J,
Kornblau SM
. Co-occurrence of FLT3-TKD and NPM1 mutations defines a highly favorable prognostic AML group. Blood Adv. 2017 Aug 22; 1(19):1546-1550.
PMID:
29296796
; PMCID:
PMC5728474
.
Citations:
24
Fields:
Hem
Hematology
Daver N
,
Kantarjian H
. FLT3 inhibition in acute myeloid leukaemia. Lancet Oncol. 2017 08; 18(8):988-989.
PMID:
28759368
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P,
Kantarjian HM
, Ghorab A, Sasaki K,
Jabbour EJ
, Nogueras Gonzalez G, Kanagal-Shamanna R, Issa GC,
Garcia-Manero G
, Kc D, Dellasala S, Pierce S,
Konopleva M
,
Wierda WG
,
Verstovsek S
,
Daver NG
,
Kadia TM
,
Borthakur G
, O'Brien S,
Estrov Z
, Ravandi F,
Cortes JE
. Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients. Cancer. 2017 Nov 15; 123(22):4391-4402.
PMID:
28743165
; PMCID:
PMC5673547
.
Citations:
47
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
,
Kantarjian H
,
Garcia-Manero G
,
Jabbour E
,
Borthakur G
, Brandt M, Pierce S, Vaughan K, Ning J, Patel K, Jorgensen J,
Pemmaraju N
,
Kadia T
,
Konopleva M
,
Andreeff M
,
DiNardo C
, Cortes J, Ward R, Craig A, Ravandi F, Nogueras Gonz?lez GM. Vosaroxin in combination with decitabine in newly diagnosed older patients with acute myeloid leukemia or high-risk myelodysplastic syndrome. Haematologica. 2017 10; 102(10):1709-1717.
PMID:
28729302
; PMCID:
PMC5622855
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Boddu P,
Kantarjian HM
,
Garcia-Manero G
, Ravandi F,
Verstovsek S
,
Jabbour E
,
Borthakur G
,
Konopleva M
,
Bhalla KN
,
Daver N
,
DiNardo CD
,
Benton CB
,
Takahashi K
,
Estrov Z
, Pierce SR,
Andreeff M
,
Cortes JE
,
Kadia TM
. Treated secondary acute myeloid leukemia: a distinct high-risk subset of AML with adverse prognosis. Blood Adv. 2017 Jul 25; 1(17):1312-1323.
PMID:
29296774
; PMCID:
PMC5727976
.
Citations:
26
Fields:
Hem
Hematology
Short NJ,
Kantarjian H
, Ravandi F, Huang X, Xiao L,
Garcia-Manero G
, Plunkett W,
Gandhi V
, Sasaki K,
Pemmaraju N
,
Daver NG
,
Borthakur G
,
Jain N
,
Konopleva M
,
Estrov Z
,
Kadia TM
,
Wierda WG
,
DiNardo CD
, Brandt M, O'Brien SM,
Cortes JE
,
Jabbour E
. A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia. Leuk Lymphoma. 2018 04; 59(4):813-820.
PMID:
28718728
; PMCID:
PMC5773400
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jabbour E
, Short NJ, Ravandi F, Huang X, Xiao L,
Garcia-Manero G
, Plunkett W,
Gandhi V
, Sasaki K,
Pemmaraju N
,
Daver NG
,
Borthakur G
,
Jain N
,
Konopleva M
,
Estrov Z
,
Kadia TM
,
Wierda WG
,
DiNardo CD
, Brandt M, O'Brien SM,
Cortes JE
,
Kantarjian H
. A randomized phase 2 study of idarubicin and cytarabine with clofarabine or fludarabine in patients with newly diagnosed acute myeloid leukemia. Cancer. 2017 Nov 15; 123(22):4430-4439.
PMID:
28708931
; PMCID:
PMC5739034
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Boddu P,
Kantarjian H
,
Garcia-Manero G
,
Allison J
,
Sharma P
,
Daver N
. The emerging role of immune checkpoint based approaches in AML and MDS. Leuk Lymphoma. 2018 04; 59(4):790-802.
PMID:
28679300
; PMCID:
PMC5872841
.
Citations:
42
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Newberry KJ, Patel K, Masarova L,
Luthra R
, Manshouri T,
Jabbour E
,
Bose P
,
Daver N
, Cortes J,
Kantarjian H
,
Verstovsek S
. Clonal evolution and outcomes in myelofibrosis after ruxolitinib discontinuation. Blood. 2017 08 31; 130(9):1125-1131.
PMID:
28674026
; PMCID:
PMC5580275
.
Citations:
75
Fields:
Hem
Hematology
Translation:
Humans
Otrock ZK,
Daver N
,
Kantarjian HM
, Eby CS. Diagnostic Challenges of Hemophagocytic Lymphohistiocytosis. Clin Lymphoma Myeloma Leuk. 2017 07; 17S:S105-S110.
PMID:
28760295
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Hust MA,
Blechacz BRA
, Bonilla DL,
Daver N
, Rojas-Hernandez CM. Adult cancer-related hemophagocytic lymphohistiocytosis - a challenging diagnosis: a case report. J Med Case Rep. 2017 Jun 27; 11(1):172.
PMID:
28651636
; PMCID:
PMC5485603
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Daver N
,
McClain K
,
Allen CE
, Parikh SA, Otrock Z, Rojas-Hernandez C,
Blechacz B
, Wang S, Minkov M, Jordan MB,
Kantarjian HM
, La Ros?e P. A consensus review on malignancy-associated hemophagocytic lymphohistiocytosis in adults. Cancer. 2017 Sep 01; 123(17):3229-3240.
PMID:
28621800
; PMCID:
PMC5568927
.
Citations:
58
Fields:
Neo
Neoplasms
Translation:
Humans
Short NJ,
Kantarjian H
,
Jabbour E
,
Cortes JE
, Thomas DA,
Rytting ME
,
Daver N
,
Alvarado Y
,
Konopleva M
,
Kebriaei P
,
Wierda WG
,
DiNardo CD
, Bivins C, McCue D, Richie MA, Ravandi F. A phase I study of moxetumomab pasudotox in adults with relapsed or refractory B-cell acute lymphoblastic leukaemia. Br J Haematol. 2018 08; 182(3):442-444.
PMID:
28616864
; PMCID:
PMC6511975
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Ragon BK,
Daver N
,
Garcia-Manero G
, Ravandi F, Cortes J,
Kadia T
,
Oran B
,
Ohanian M
,
Ferrajoli A
,
Pemmaraju N
,
Kantarjian HM
,
Borthakur G
. Minimal residual disease eradication with epigenetic therapy in core binding factor acute myeloid leukemia. Am J Hematol. 2017 Sep; 92(9):845-850.
PMID:
28494506
; PMCID:
PMC5779853
.
Citations:
14
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Masarova L,
Bose P
,
Daver N
,
Pemmaraju N
, Newberry KJ, Manshouri T, Cortes J,
Kantarjian HM
,
Verstovsek S
. Patients with post-essential thrombocythemia and post-polycythemia vera differ from patients with primary myelofibrosis. Leuk Res. 2017 08; 59:110-116.
PMID:
28601551
; PMCID:
PMC5573611
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Strati P, Masarova L,
Bose P
,
Daver N
,
Pemmaraju N
,
Verstovsek S
. Haptoglobin is frequently low in patients with myelofibrosis: Clinical relevance. Leuk Res. 2017 06; 57:85-88.
PMID:
28324773
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Assi R,
Verstovsek S
,
Daver N
. 'JAK-ing' up the treatment of primary myelofibrosis: building better combination strategies. Curr Opin Hematol. 2017 03; 24(2):115-124.
PMID:
28072602
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
Montalban-Bravo G,
Benton CB
, Wang SA, Ravandi F,
Kadia T
, Cortes J,
Daver N
,
Takahashi K
,
DiNardo C
,
Jabbour E
,
Borthakur G
,
Konopleva M
, Pierce S,
Bueso-Ramos C
, Patel K,
Kornblau S
,
Kantarjian H
, Young KH,
Garcia-Manero G
,
Andreeff M
. More than 1 TP53 abnormality is a dominant characteristic of pure erythroid leukemia. Blood. 2017 05 04; 129(18):2584-2587.
PMID:
28246192
; PMCID:
PMC5418636
.
Citations:
16
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Smith DP, Sahasrabhojane P, Wadsworth WD, Fellman BM, Ajami NJ,
Shpall EJ
,
Daver N
, Guindani M,
Petrosino JF
,
Kontoyiannis DP
,
Shelburne SA
, Galloway-Pe?a JR. Characterization of oral and gut microbiome temporal variability in hospitalized cancer patients. Genome Med. 2017 02 28; 9(1):21.
PMID:
28245856
; PMCID:
PMC5331640
.
Citations:
38
Fields:
Gen
Genetics
Translation:
Humans
Cells
Jabbour E
, Strati P, Cabrero M, O'Brien S, Ravandi F,
Bueso-Ramos C
, Wei Q, Hu J, Abi Aad S, Short NJ,
Dinardo C
,
Daver N
,
Kadia T
,
Wierda W
, Wei Y,
Colla S
,
Borthakur G
, Cortes J,
Estrov Z
,
Kantarjian H
,
Garcia-Manero G
. Impact of achievement of complete cytogenetic response on outcome in patients with myelodysplastic syndromes treated with hypomethylating agents. Am J Hematol. 2017 Apr; 92(4):351-358.
PMID:
28076892
; PMCID:
PMC5439522
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Cells
Gaballa S,
Saliba R
,
Oran B
, Brammer JE, Chen J,
Rondon G
,
Alousi AM
,
Kebriaei P
,
Marin D
,
Popat UR
,
Andersson BS
,
Shpall EJ
,
Jabbour E
,
Daver N
,
Andreeff M
, Ravandi F, Cortes J, Patel K,
Champlin RE
,
Ciurea SO
. Relapse risk and survival in patients with FLT3 mutated acute myeloid leukemia undergoing stem cell transplantation. Am J Hematol. 2017 Apr; 92(4):331-337.
PMID:
28052408
; PMCID:
PMC5352512
.
Citations:
19
Fields:
Hem
Hematology
Translation:
Humans
Short NJ,
Kantarjian HM
, Sasaki K, Ravandi F, Ko H, Cameron Yin C,
Garcia-Manero G
,
Cortes JE
, Garris R, O'Brien SM, Patel K, Khouri M, Thomas D,
Jain N
,
Kadia TM
,
Daver NG
,
Benton CB
, Issa GC,
Konopleva M
,
Jabbour E
. Poor outcomes associated with +der(22)t(9;22) and -9/9p in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia receiving chemotherapy plus a tyrosine kinase inhibitor. Am J Hematol. 2017 Mar; 92(3):238-243.
PMID:
28006851
; PMCID:
PMC5495018
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Cells
Daver N
,
Kantarjian H
. Malignancy-associated haemophagocytic lymphohistiocytosis in adults. Lancet Oncol. 2017 02; 18(2):169-171.
PMID:
28214404
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Pinnix CC
, Chi L,
Jabbour EJ
,
Milgrom SA
, Smith GL,
Daver N
,
Garg N
,
Cykowski MD
,
Fuller G
, Cachia D, Kamiya-Matsuoka C,
Woodman K
,
Dinardo C
,
Jain N
,
Kadia TM
,
Pemmaraju N
,
Ohanian M
,
Konopleva M
,
Kantarjian HM
,
Dabaja BS
. Dorsal column myelopathy after intrathecal chemotherapy for leukemia. Am J Hematol. 2017 Feb; 92(2):155-160.
PMID:
27874212
; PMCID:
PMC5338569
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Masarova L,
Kantarjian H
, Garcia-Mannero G, Ravandi F,
Sharma P
,
Daver N
. Harnessing the Immune System Against Leukemia: Monoclonal Antibodies and Checkpoint Strategies for AML. Adv Exp Med Biol. 2017; 995:73-95.
PMID:
28321813
.
Citations:
13
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Abaza Y,
Kantarjian H
,
Garcia-Manero G
, Estey E,
Borthakur G
,
Jabbour E
, Faderl S, O'Brien S,
Wierda W
, Pierce S, Brandt M, McCue D,
Luthra R
, Patel K,
Kornblau S
,
Kadia T
,
Daver N
,
DiNardo C
,
Jain N
,
Verstovsek S
,
Ferrajoli A
,
Andreeff M
,
Konopleva M
,
Estrov Z
, Foudray M, McCue D, Cortes J, Ravandi F. Long-term outcome of acute promyelocytic leukemia treated with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab. Blood. 2017 03 09; 129(10):1275-1283.
PMID:
28003274
; PMCID:
PMC5413297
.
Citations:
73
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Shah AR,
Muzzafar T
, Assi R,
Schellingerhout D
,
Estrov Z
, Tamamyan G,
Kantarjian H
,
Daver N
. Hemophagocytic lymphohistiocytosis in adults: An under recognized entity. BBA Clin. 2017 Jun; 7:36-40.
PMID:
28070498
; PMCID:
PMC5219626
.
Citations:
7
Tamamyan G,
Kadia T
, Ravandi F,
Borthakur G
, Cortes J,
Jabbour E
,
Daver N
,
Ohanian M
,
Kantarjian H
,
Konopleva M
. Frontline treatment of acute myeloid leukemia in adults. Crit Rev Oncol Hematol. 2017 Feb; 110:20-34.
PMID:
28109402
; PMCID:
PMC5410376
.
Citations:
42
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Ragon BK,
Kantarjian H
,
Jabbour E
, Ravandi F, Cortes J,
Borthakur G
, DeBose L,
Zeng Z
, Schneider H,
Pemmaraju N
,
Garcia-Manero G
,
Kornblau S
,
Wierda W
,
Burger J
,
DiNardo CD
,
Andreeff M
,
Konopleva M
,
Daver N
. Buparlisib, a PI3K inhibitor, demonstrates acceptable tolerability and preliminary activity in a phase I trial of patients with advanced leukemias. Am J Hematol. 2017 Jan; 92(1):7-11.
PMID:
27673440
; PMCID:
PMC5361214
.
Citations:
19
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Jabbour E
, Faderl S, Sasaki K,
Kadia T
,
Daver N
,
Pemmaraju N
, Patel K,
Khoury JD
,
Bueso-Ramos C
, Bohannan Z, Ravandi F,
Borthakur G
,
Verstovsek S
, Miller D, Maduike R,
Hosing C
,
Kantarjian HM
,
Garcia-Manero G
. Phase 2 study of low-dose clofarabine plus cytarabine for patients with higher-risk myelodysplastic syndrome who have relapsed or are refractory to hypomethylating agents. Cancer. 2017 Feb 15; 123(4):629-637.
PMID:
27741352
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Issa GC,
Kantarjian HM
, Yin CC, Qiao W, Ravandi F, Thomas D, Short NJ, Sasaki K,
Garcia-Manero G
,
Kadia TM
,
Cortes JE
,
Daver N
,
Borthakur G
,
Jain N
,
Konopleva M
,
Khouri I
,
Kebriaei P
,
Champlin RE
, Pierce S, O'Brien SM,
Jabbour E
. Prognostic impact of pretreatment cytogenetics in adult Philadelphia chromosome-negative acute lymphoblastic leukemia in the era of minimal residual disease. Cancer. 2017 02 01; 123(3):459-467.
PMID:
27696391
; PMCID:
PMC5321542
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Alatrash G,
Daver N
,
Mittendorf EA
. Targeting Immune Checkpoints in Hematologic Malignancies. Pharmacol Rev. 2016 10; 68(4):1014-1025.
PMID:
27664133
.
Citations:
15
Fields:
Pha
Pharmacology
Translation:
Humans
Khan M, Sarfraz M,
Daver N
. Myelodysplastic/myeloproliferative neoplasms: a disease in need of recognition. Future Oncol. 2017 Jan; 13(2):117-120.
PMID:
27676208
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Ravandi F,
Jorgensen J
,
Borthakur G
,
Jabbour E
,
Kadia T
, Pierce S, Brandt M, Wang S,
Konoplev S
, Wang X, Huang X,
Daver N
,
DiNardo C
,
Andreeff M
,
Konopleva M
,
Estrov Z
,
Garcia-Manero G
, Cortes J,
Kantarjian H
. Persistence of minimal residual disease assessed by multiparameter flow cytometry is highly prognostic in younger patients with acute myeloid leukemia. Cancer. 2017 02 01; 123(3):426-435.
PMID:
27657543
; PMCID:
PMC5258784
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
,
Konopleva M
. Cotargeting BCL-2 and BCL-XL for maximal efficacy in ALL. Blood. 2016 09 08; 128(10):1316-7.
PMID:
27609539
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Sasaki K,
Jabbour E
, Cortes J,
Kadia T
,
Garcia-Manero G
,
Borthakur G
, Jain P, Pierce S,
Daver N
,
Takahashi K
, O'Brien S,
Kantarjian H
, Ravandi F. Outcome of Patients With Therapy-Related Acute Myeloid Leukemia With or Without a History of Myelodysplasia. Clin Lymphoma Myeloma Leuk. 2016 11; 16(11):616-624.
PMID:
27601000
; PMCID:
PMC5408349
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Takahashi K
,
Kantarjian HM
, Yang Y, Sasaki K, Jain P, DellaSala S, Ravandi F,
Kadia T
,
Pemmaraju N
,
Daver N
,
Borthakur G
,
Garcia-Manero G
,
Jabbour E
,
Cortes JE
. A propensity score matching analysis of dasatinib and nilotinib as a frontline therapy for patients with chronic myeloid leukemia in chronic phase. Cancer. 2016 Nov 15; 122(21):3336-3343.
PMID:
27509035
; PMCID:
PMC5073019
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Naqvi K
,
Daver N
,
Pemmaraju N
,
Bose P
,
Garcia-Manero G
, Cortes J,
Kantarjian HM
,
Verstovsek S
. Clinical use of ruxolitinib in an academic medical center in unselected patients with myeloproliferative neoplasms not on clinical study. Leuk Lymphoma. 2017 04; 58(4):866-871.
PMID:
27494751
; PMCID:
PMC5521009
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Sasaki K,
Jabbour EJ
, Ravandi F, Short NJ, Thomas DA,
Garcia-Manero G
,
Daver NG
,
Kadia TM
,
Konopleva MY
,
Jain N
, Issa GC, Jeanis V, Moore HG, Garris RS,
Pemmaraju N
,
Cortes JE
, O'Brien SM,
Kantarjian HM
. Hyper-CVAD plus ponatinib versus hyper-CVAD plus dasatinib as frontline therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: A propensity score analysis. Cancer. 2016 Dec 01; 122(23):3650-3656.
PMID:
27479888
; PMCID:
PMC5321539
.
Citations:
51
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Kadia TM
, Jain P, Ravandi F,
Garcia-Manero G
, Andreef M,
Takahashi K
,
Borthakur G
,
Jabbour E
,
Konopleva M
,
Daver NG
,
Dinardo C
, Pierce S, Kanagal-Shamanna R, Patel K,
Estrov Z
, Cortes J,
Kantarjian HM
. TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes. Cancer. 2016 Nov 15; 122(22):3484-3491.
PMID:
27463065
; PMCID:
PMC5269552
.
Citations:
71
Fields:
Neo
Neoplasms
Rytting ME
,
Jabbour EJ
,
Jorgensen JL
, Ravandi F, Franklin AR,
Kadia TM
,
Pemmaraju N
,
Daver NG
,
Ferrajoli A
,
Garcia-Manero G
,
Konopleva MY
,
Borthakur G
, Garris R, Wang S, Pierce S, Schroeder K,
Kornblau SM
, Thomas DA,
Cortes JE
, O'Brien SM,
Kantarjian HM
. Final results of a single institution experience with a pediatric-based regimen, the augmented Berlin-Frankfurt-M?nster, in adolescents and young adults with acute lymphoblastic leukemia, and comparison to the hyper-CVAD regimen. Am J Hematol. 2016 08; 91(8):819-23.
PMID:
27178680
; PMCID:
PMC5558853
.
Citations:
36
Fields:
Hem
Hematology
Translation:
Humans
Cells
Nazha A,
Khoury JD
,
Verstovsek S
,
Daver N
. Second line therapies in polycythemia vera: What is the optimal strategy after hydroxyurea failure? Crit Rev Oncol Hematol. 2016 Sep; 105:112-7.
PMID:
27401783
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ouyang J, Goswami M, Peng J,
Zuo Z
,
Daver N
,
Borthakur G
, Tang G, Medeiros LJ,
Jorgensen JL
, Ravandi F, Wang SA. Comparison of Multiparameter Flow Cytometry Immunophenotypic Analysis and Quantitative RT-PCR for the Detection of Minimal Residual Disease of Core Binding Factor Acute Myeloid Leukemia. Am J Clin Pathol. 2016 Jun; 145(6):769-77.
PMID:
27298396
; PMCID:
PMC6272803
.
Citations:
15
Fields:
Pat
Pathology
Translation:
Humans
Daver N
, Ravandi F. Enhancing cytotoxicity of immunotoxins in AML. Blood. 2016 06 09; 127(23):2787-8.
PMID:
27282944
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
Tamamyan GN,
Kantarjian HM
,
Ning J
, Jain P, Sasaki K, McClain KL,
Allen CE
, Pierce SA,
Cortes JE
, Ravandi F,
Konopleva MY
,
Garcia-Manero G
,
Benton CB
, Chihara D,
Rytting ME
, Wang S, Abdelall W,
Konoplev SN
,
Daver NG
. Malignancy-associated hemophagocytic lymphohistiocytosis in adults: Relation to hemophagocytosis, characteristics, and outcomes. Cancer. 2016 09 15; 122(18):2857-66.
PMID:
27244347
; PMCID:
PMC5014667
.
Citations:
30
Fields:
Neo
Neoplasms
Translation:
Humans
Sasaki K,
Kantarjian H
,
Jabbour E
, Ravandi F,
Takahashi K
,
Konopleva M
,
Borthakur G
,
Garcia-Manero G
,
Wierda W
,
Daver N
, Jain P, Satta T, Pierce S, Rios MB,
Cortes JE
. Frontline therapy with high-dose imatinib versus second generation tyrosine kinase inhibitor in patients with chronic-phase chronic myeloid leukemia - a propensity score analysis. Haematologica. 2016 08; 101(8):e324-7.
PMID:
27175025
; PMCID:
PMC4967581
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Smith DP, Sahasrabhojane P, Ajami NJ, Wadsworth WD,
Daver NG
,
Chemaly RF
, Marsh L, Ghantoji SS,
Pemmaraju N
,
Garcia-Manero G
,
Rezvani K
,
Alousi AM
,
Wargo JA
,
Shpall EJ
, Futreal PA, Guindani M,
Petrosino JF
,
Kontoyiannis DP
,
Shelburne SA
, Galloway-Pe?a JR. The role of the gastrointestinal microbiome in infectious complications during induction chemotherapy for acute myeloid leukemia. Cancer. 2016 07 15; 122(14):2186-96.
PMID:
27142181
; PMCID:
PMC5574182
.
Citations:
56
Fields:
Neo
Neoplasms
Translation:
Humans
Takahashi K
, Patel K,
Bueso-Ramos C
, Zhang J, Gumbs C,
Jabbour E
,
Kadia T
, Andreff M,
Konopleva M
,
DiNardo C
,
Daver N
, Cortes J,
Estrov Z
,
Futreal A
,
Kantarjian H
,
Garcia-Manero G
. Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents. Oncotarget. 2016 Mar 22; 7(12):14172-87.
PMID:
26871476
; PMCID:
PMC4924706
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Daver N
, Cortes J,
Kantarjian H
, Ravandi F. Acute myeloid leukemia: advancing clinical trials and promising therapeutics. Expert Rev Hematol. 2016 May; 9(5):433-45.
PMID:
26910051
; PMCID:
PMC5006674
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Vitale C,
Jabbour E
, Lu X, Yabe M,
Kanagal Shamanna R
,
Daver N
,
Pemmaraju N
,
Bueso-Ramos CE
,
Takahashi K
. Acute promyelocytic leukemia presented as a relapse of acute myeloid leukemia. Am J Hematol. 2016 Jun; 91(4):E274-6.
PMID:
26798971
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Jain P, Tang G,
Huh YO
, Yin CC,
Zuo Z
,
Pemmaraju N
,
Estrov Z
,
Daver N
. Philadelphia-positive dimorphic blasts in mixed-phenotype acute leukemia with TET2 mutation. Am J Hematol. 2016 06; 91(6):647-8.
PMID:
26799924
; PMCID:
PMC4870100
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Short NJ,
Kantarjian HM
,
Jabbour EJ
, O'Brien SM, Faderl S,
Burger JA
, Garris R, Qiao W, Huang X,
Jain N
,
Konopleva M
,
Kadia TM
,
Daver N
,
Borthakur G
,
Cortes JE
, Ravandi F. Prognostic impact of persistent cytogenetic abnormalities at complete remission in adult patients with acute lymphoblastic leukemia. Am J Hematol. 2016 Jun; 91(4):385-9.
PMID:
26800008
; PMCID:
PMC5834229
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Jain P, Tang G,
Konoplev SN
, Kanagal-Shamanna R, Wang SA,
Pemmaraju N
,
Daver N
,
Estrov Z
. Synchronous del5q myelodysplastic syndrome (del5qMDS) and adult B-cell acute lymphoblastic leukemia (B-ALL) with TET2 and TP53 mutations. Am J Hematol. 2016 Mar; 91(3):354-5.
PMID:
26437693
; PMCID:
PMC4764477
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Jain P,
Kantarjian H
,
Patel KP
, Gonzalez GN,
Luthra R
,
Kanagal Shamanna R
, Sasaki K,
Jabbour E
, Romo CG,
Kadia TM
,
Pemmaraju N
,
Daver N
,
Borthakur G
,
Estrov Z
, Ravandi F, O'Brien S, Cortes J. Impact of BCR-ABL transcript type on outcome in patients with chronic-phase CML treated with tyrosine kinase inhibitors. Blood. 2016 Mar 10; 127(10):1269-75.
PMID:
26729897
; PMCID:
PMC4786836
.
Citations:
50
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Sasaki K,
Lahoti A
,
Jabbour E
, Jain P, Pierce S,
Borthakur G
,
Daver N
,
Kadia T
,
Pemmaraju N
,
Ferrajoli A
, O'Brien S,
Kantarjian H
, Cortes J. Clinical Safety and Efficacy of Nilotinib or Dasatinib in Patients With Newly Diagnosed Chronic-Phase Chronic Myelogenous Leukemia and Pre-Existing Liver and/or Renal Dysfunction. Clin Lymphoma Myeloma Leuk. 2016 Mar; 16(3):152-62.
PMID:
26796981
; PMCID:
PMC4769134
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
,
Konopleva M
. Sorafenib and novel multikinase inhibitors in AML. Lancet Oncol. 2015 Dec; 16(16):1582-3.
PMID:
26549588
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Sasaki K,
Kantarjian HM
, Jain P,
Jabbour EJ
, Ravandi F,
Konopleva M
,
Borthakur G
,
Takahashi K
,
Pemmaraju N
,
Daver N
, Pierce SA, O'Brien SM,
Cortes JE
. Conditional survival in patients with chronic myeloid leukemia in chronic phase in the era of tyrosine kinase inhibitors. Cancer. 2016 Jan 15; 122(2):238-48.
PMID:
26479889
; PMCID:
PMC4707980
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Badar T,
Patel KP
, Thompson PA,
DiNardo C
,
Takahashi K
, Cabrero M,
Borthakur G
, Cortes J,
Konopleva M
,
Kadia T
, Bohannan Z, Pierce S,
Jabbour EJ
, Ravandi F,
Daver N
, Luthra R,
Kantarjian H
,
Garcia-Manero G
. Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes. Leuk Res. 2015 Dec; 39(12):1367-74.
PMID:
26547258
; PMCID:
PMC4822515
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jabbour E
,
Kantarjian H
, Ravandi F, Thomas D, Huang X, Faderl S,
Pemmaraju N
,
Daver N
,
Garcia-Manero G
, Sasaki K, Cortes J, Garris R, Yin CC,
Khoury JD
,
Jorgensen J
,
Estrov Z
, Bohannan Z,
Konopleva M
,
Kadia T
,
Jain N
,
DiNardo C
,
Wierda W
, Jeanis V, O'Brien S. Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a single-centre, phase 2 study. Lancet Oncol. 2015 Nov; 16(15):1547-1555.
PMID:
26432046
; PMCID:
PMC4816046
.
Citations:
83
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Badar T,
Kantarjian HM
, Nogueras-Gonzalez GM,
Borthakur G
, Garcia Manero G,
Andreeff M
,
Konopleva M
,
Kadia TM
,
Daver N
,
Wierda WG
, Luthra R, Patel K,
Oran B
,
Champlin R
, Ravandi F,
Cortes JE
. Improvement in clinical outcome of FLT3 ITD mutated acute myeloid leukemia patients over the last one and a half decade. Am J Hematol. 2015 Nov; 90(11):1065-70.
PMID:
26299958
; PMCID:
PMC4618182
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
Jain P,
Kantarjian H
,
Jabbour E
, Gonzalez GN,
Borthakur G
,
Pemmaraju N
,
Daver N
, Gachimova E,
Ferrajoli A
,
Kornblau S
, Ravandi F, O'Brien S, Cortes J. Ponatinib as first-line treatment for patients with chronic myeloid leukaemia in chronic phase: a phase 2 study. Lancet Haematol. 2015 Sep; 2(9):e376-83.
PMID:
26436130
; PMCID:
PMC4587395
.
Citations:
30
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Nazha A,
Khoury JD
, Rampal RK,
Daver N
. Fibrogenesis in Primary Myelofibrosis: Diagnostic, Clinical, and Therapeutic Implications. Oncologist. 2015 Oct; 20(10):1154-60.
PMID:
26304912
; PMCID:
PMC4591957
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Issa JJ, Roboz G, Rizzieri D,
Jabbour E
, Stock W, O'Connell C, Yee K, Tibes R, Griffiths EA, Walsh K,
Daver N
, Chung W, Naim S, Taverna P, Oganesian A, Hao Y, Lowder JN, Azab M,
Kantarjian H
. Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study. Lancet Oncol. 2015 Sep; 16(9):1099-1110.
PMID:
26296954
; PMCID:
PMC5557041
.
Citations:
114
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Badar T, Shetty A,
Bueso-Ramos C
,
Cortes J
,
Konopleva M
,
Borthakur G
, Pierce S,
Huang X
, Chen HC,
Kadia T
,
Daver N
,
Dinardo C
, O'Brien S,
Garcia-Manero G
,
Kantarjian H
, Ravandi F. Bone marrow necrosis in acute leukemia: Clinical characteristic and outcome. Am J Hematol. 2015 Sep; 90(9):769-73.
PMID:
26017166
; PMCID:
PMC4546505
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Daver N
, Cortes J, Newberry K,
Jabbour E
, Zhou L, Wang X, Pierce S,
Kadia T
, Sasaki K,
Borthakur G
, Ravandi F,
Pemmaraju N
,
Kantarjian H
,
Verstovsek S
. Ruxolitinib in combination with lenalidomide as therapy for patients with myelofibrosis. Haematologica. 2015 Aug; 100(8):1058-63.
PMID:
26088933
; PMCID:
PMC5004422
.
Citations:
29
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Badar T,
Kantarjian HM
, Ravandi F,
Jabbour E
,
Borthakur G
,
Cortes JE
,
Pemmaraju N
, Pierce SR, Newberry KJ,
Daver N
,
Verstovsek S
. Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic/acute myeloid leukemia phase. Leuk Res. 2015 Sep; 39(9):950-6.
PMID:
26183878
; PMCID:
PMC4546869
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Sasaki K, Strom SS, O'Brien S,
Jabbour E
, Ravandi F,
Konopleva M
,
Borthakur G
,
Pemmaraju N
,
Daver N
, Jain P, Pierce S,
Kantarjian H
,
Cortes JE
. Relative survival in patients with chronic-phase chronic myeloid leukaemia in the tyrosine-kinase inhibitor era: analysis of patient data from six prospective clinical trials. Lancet Haematol. 2015 May; 2(5):e186-93.
PMID:
26688093
; PMCID:
PMC4884053
.
Citations:
86
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ouyang J, Goswami M,
Tang G
, Peng J, Ravandi F,
Daver N
,
Routbort M
,
Konoplev S
,
Lin P
,
Medeiros LJ
,
Jorgensen JL
, Wang SA. The clinical significance of negative flow cytometry immunophenotypic results in a morphologically scored positive bone marrow in patients following treatment for acute myeloid leukemia. Am J Hematol. 2015 Jun; 90(6):504-10.
PMID:
25732229
; PMCID:
PMC5594737
.
Citations:
14
Fields:
Hem
Hematology
Translation:
Humans
Cells
Daver N
, Cortes J, Ravandi F,
Patel KP
,
Burger JA
,
Konopleva M
,
Kantarjian H
. Secondary mutations as mediators of resistance to targeted therapy in leukemia. Blood. 2015 May 21; 125(21):3236-45.
PMID:
25795921
; PMCID:
PMC4440880
.
Citations:
63
Fields:
Hem
Hematology
Translation:
Humans
Strati P,
Kantarjian H
, Ravandi F, Nazha A,
Borthakur G
,
Daver N
,
Kadia T
,
Estrov Z
,
Garcia-Manero G
,
Konopleva M
, Rajkhowa T, Durand M,
Andreeff M
, Levis M, Cortes J. Phase I/II trial of the combination of midostaurin (PKC412) and 5-azacytidine for patients with acute myeloid leukemia and myelodysplastic syndrome. Am J Hematol. 2015 Apr; 90(4):276-81.
PMID:
25530214
; PMCID:
PMC4376596
.
Citations:
61
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Daver N
, Boumber Y,
Kantarjian H
, Ravandi F, Cortes J,
Rytting ME
, Kawedia JD, Basnett J, Culotta KS,
Zeng Z
, Lu H, Richie MA, Garris R, Xiao L, Liu W,
Baggerly KA
,
Jabbour E
, O'Brien S,
Burger J
, Bendall LJ, Thomas D,
Konopleva M
. A Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia. Clin Cancer Res. 2015 Jun 15; 21(12):2704-14.
PMID:
25724525
; PMCID:
PMC4470787
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Kadia T
,
Kantarjian H
,
Garcia-Manero G
,
Borthakur G
, Wang X, Patel K,
Jabbour E
, Brandt M,
Daver N
,
Pemmaraju N
, Pierce S,
Cortes J
, Ravandi F. Prognostic significance of the Medical Research Council cytogenetic classification compared with the European LeukaemiaNet risk classification system in acute myeloid leukaemia. Br J Haematol. 2015 Aug; 170(4):590-3.
PMID:
25716073
; PMCID:
PMC4977576
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Daver N
, Thomas D, Ravandi F, Cortes J, Garris R,
Jabbour E
,
Garcia-Manero G
,
Borthakur G
,
Kadia T
,
Rytting M
,
Konopleva M
,
Kantarjian H
, O'Brien S. Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Haematologica. 2015 May; 100(5):653-61.
PMID:
25682595
; PMCID:
PMC4420214
.
Citations:
61
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Konopleva M
,
Thall PF
, Yi CA,
Borthakur G
, Coveler A,
Bueso-Ramos C
, Benito J,
Konoplev S
, Gu Y, Ravandi F,
Jabbour E
, Faderl S, Thomas D, Cortes J,
Kadia T
,
Kornblau S
,
Daver N
,
Pemmaraju N
, Nguyen HQ, Feliu J, Lu H, Wei C, Wilson WR, Melink TJ, Gutheil JC,
Andreeff M
, Estey EH,
Kantarjian H
. Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia. Haematologica. 2015 Jul; 100(7):927-34.
PMID:
25682597
; PMCID:
PMC4486227
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Pemmaraju N
, Sasaki K, Johnson D,
Daver N
,
Afshar-Kharghan V
, Chen M, Ahmed S,
Colen RR
,
Kwon M
,
Huh Y
,
Borthakur G
. Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature. Front Oncol. 2015; 5:29.
PMID:
25717439
; PMCID:
PMC4324079
.
Citations:
1
Cachia D, Kamiya-Matsuoka C,
Pinnix CC
, Chi L,
Kantarjian HM
,
Cortes JE
,
Daver N
,
Woodman K
. Myelopathy following intrathecal chemotherapy in adults: a single institution experience. J Neurooncol. 2015 Apr; 122(2):391-8.
PMID:
25666482
; PMCID:
PMC4369460
.
Citations:
13
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
CT
Clinical Trials
Daver N
, Cortes J. The changing face of acute myeloid leukemia therapeutics in the elderly population. South Asian J Cancer. 2015 Jan-Mar; 4(1):1-2.
PMID:
25839008
; PMCID:
PMC4382773
.
Citations:
Kazmi SM,
Pemmaraju N
,
Patel KP
, Cohen PR,
Daver N
, Tran KM, Ravandi F,
Duvic M
,
Garcia-Manero G
, Pierce S, Nazha A,
Borthakur G
,
Kantarjian H
, Cortes J. Characteristics of Sweet Syndrome in patients with acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015 Jun; 15(6):358-363.
PMID:
25630528
; PMCID:
PMC4457594
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
DiNardo CD
,
Daver N
,
Jabbour E
,
Kadia T
,
Borthakur G
,
Konopleva M
,
Pemmaraju N
, Yang H, Pierce S,
Wierda W
,
Bueso-Ramos C
,
Patel KP
,
Cortes JE
, Ravandi F,
Kantarjian HM
,
Garcia-Manero G
. Sequential azacitidine and lenalidomide in patients with high-risk myelodysplastic syndromes and acute myeloid leukaemia: a single-arm, phase 1/2 study. Lancet Haematol. 2015 Jan; 2(1):e12-20.
PMID:
26687423
; PMCID:
PMC4936479
.
Citations:
6
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Kadia TM
,
Kantarjian HM
, Thomas DA, O'Brien S,
Estrov Z
, Ravandi F,
Jabbour E
,
Pemmaraju N
,
Daver N
, Wang X, Jain P, Pierce S, Brandt M,
Garcia-Manero G
,
Cortes J
,
Borthakur G
. Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia. Am J Hematol. 2015 Feb; 90(2):120-4.
PMID:
25368968
; PMCID:
PMC4447180
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Jabbour EJ
,
Garcia-Manero G
, Strati P, Mishra A, Al Ali NH, Padron E, Lancet J,
Kadia T
,
Daver N
, O'Brien S, Steensma DP, Sekeres MA, Gore SD, Dezern A, Roboz GJ, List AF,
Kantarjian HM
, Komrokji RS. Outcome of patients with low-risk and intermediate-1-risk myelodysplastic syndrome after hypomethylating agent failure: a report on behalf of the MDS Clinical Research Consortium. Cancer. 2015 Mar 15; 121(6):876-82.
PMID:
25410759
; PMCID:
PMC4378905
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Eghtedar A, Rodriguez I,
Kantarjian H
, O'Brien S,
Daver N
,
Garcia-Manero G
,
Ferrajoli A
,
Kadia T
, Pierce S, Cortes J, Ravandi F. Incidence of secondary neoplasms in patients with acute promyelocytic leukemia treated with all-trans retinoic acid plus chemotherapy or with all-trans retinoic acid plus arsenic trioxide. Leuk Lymphoma. 2015 May; 56(5):1342-5.
PMID:
25120050
; PMCID:
PMC4417657
.
Citations:
8
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Sasaki K,
Pemmaraju N
,
Westin JR
, Wang WL,
Khoury JD
, Podoloff DA,
Moon B
,
Daver N
,
Borthakur G
. A single case of rosai-dorfman disease marked by pathologic fractures, kidney failure, and liver cirrhosis treated with single-agent cladribine. Front Oncol. 2014; 4:297.
PMID:
25401088
; PMCID:
PMC4212618
.
Citations:
4
Daver N
,
Kantarjian H
, Marcucci G, Pierce S, Brandt M,
Dinardo C
,
Pemmaraju N
,
Garcia-Manero G
, O'Brien S,
Ferrajoli A
,
Verstovsek S
,
Popat U
,
Hosing C
,
Anderlini P
,
Borthakur G
,
Kadia T
,
Cortes J
, Ravandi F. Clinical characteristics and outcomes in patients with acute promyelocytic leukaemia and hyperleucocytosis. Br J Haematol. 2015 Mar; 168(5):646-53.
PMID:
25312977
; PMCID:
PMC4323735
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Strati P,
Pemmaraju N
,
Estrov Z
, Cardenas-Turanzas M, Pierce S, Newberry KJ,
Daver N
,
Cortes J
,
Kantarjian H
,
Verstovsek S
. Clinical significance of microcytosis in patients with primary myelofibrosis. Leuk Res. 2014 Oct; 38(10):1212-6.
PMID:
25217891
; PMCID:
PMC4182146
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Rytting ME
, Thomas DA, O'Brien SM,
Ravandi-Kashani F
,
Jabbour EJ
, Franklin AR,
Kadia TM
,
Pemmaraju N
,
Daver NG
,
Ferrajoli A
,
Garcia-Manero G
,
Konopleva MY
,
Cortes JE
,
Borthakur G
, Garris R, Cardenas-Turanzas M, Schroeder K,
Jorgensen JL
,
Kornblau SM
,
Kantarjian HM
. Augmented Berlin-Frankfurt-M?nster therapy in adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL). Cancer. 2014 Dec 01; 120(23):3660-8.
PMID:
25042398
; PMCID:
PMC4239168
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Jabbour E
,
Garcia-Manero G
, Cornelison AM,
Cortes JE
, Ravandi F,
Daver N
,
Kadia T
, Teng A,
Kantarjian H
. The effect of decitabine dose modification and myelosuppression on response and survival in patients with myelodysplastic syndromes. Leuk Lymphoma. 2015 Feb; 56(2):390-4.
PMID:
24844364
; PMCID:
PMC4297591
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Daver N
,
Verstovsek S
. Ruxolitinib and DNA methyltransferase-inhibitors: a foray into combination regimens in myelofibrosis. Leuk Lymphoma. 2015 Feb; 56(2):279-80.
PMID:
24913500
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Pemmaraju N
, Shah D,
Kantarjian H
,
Orlowski RZ
,
Baladandayuthapani V
,
Jain N
, Wagner V,
Garcia-Manero G
, Shah J, Ravandi F, Pierce S,
Takahashi K
,
Daver N
, Nazha A,
Verstovsek S
,
Jabbour E
, De Lima M,
Champlin R
, Cortes J,
Qazilbash MH
, Nogueras Gonz?lez GM. Characteristics and outcomes of patients with multiple myeloma who develop therapy-related myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015 Feb; 15(2):110-4.
PMID:
25107338
; PMCID:
PMC4294996
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
, Shastri A,
Kadia T
, Newberry K,
Pemmaraju N
,
Jabbour E
, Zhou L, Pierce S,
Cortes J
,
Kantarjian H
,
Verstovsek S
. Phase II study of pomalidomide in combination with prednisone in patients with myelofibrosis and significant anemia. Leuk Res. 2014 Sep; 38(9):1126-9.
PMID:
25047979
; PMCID:
PMC4157096
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Pemmaraju N
, Chang E,
Daver N
, Patel K,
Jorgensen J
,
Sabloff B
,
Verstovsek S
,
Borthakur G
. Extramedullary acute myeloid leukemia: leukemic pleural effusion, case report and review of the literature. Front Oncol. 2014; 4:130.
PMID:
24918086
; PMCID:
PMC4040935
.
Citations:
2
Daver N
, Kim H,
Dinardo C
,
Jabbour E
,
Kadia T
,
Borthakur G
, Pierce S, Shan J, Cardenas-Turanzas M,
Cortes J
, Ravandi F,
Wierda W
,
Estrov Z
, Faderl S,
Wei Y
,
Kantarjian H
,
Garcia-Manero G
, Quint?s-Cardama A. A prognostic model of therapy-related myelodysplastic syndrome for predicting survival and transformation to acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2014 Oct; 14(5):401-10.
PMID:
24875590
; PMCID:
PMC4167474
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Ghanem H,
Garcia-Manero G
, Faderl S, Ravandi F, Cortes J, Katragadda L, O'Brien S,
Daver N
, Pierce S,
Kadia T
,
Kantarjian H
,
Jabbour E
. Outcomes of patients with myelodysplatic syndrome and chronic myelomonocytic leukemia post clofarabine failure. Ther Adv Hematol. 2014 Apr; 5(2):29-34.
PMID:
24688752
; PMCID:
PMC3949300
.
Citations:
1
Jabbour E
,
Daver N
,
Champlin R
, Mathisen M,
Oran B
,
Ciurea S
,
Khouri I
, Cornelison AM, Ghanem H, Cardenas-Turanzas M,
Popat U
, Ravandi F, Giralt S,
Garcia-Manero G
,
Cortes J
,
Kantarjian H
, de Lima M. Allogeneic stem cell transplantation as initial salvage for patients with acute myeloid leukemia refractory to high-dose cytarabine-based induction chemotherapy. Am J Hematol. 2014 Apr; 89(4):395-8.
PMID:
24375514
; PMCID:
PMC4140180
.
Citations:
15
Fields:
Hem
Hematology
Translation:
Humans
Cells
Daver N
,
Naqvi K
,
Jabbour E
,
Kadia T
,
DiNardo C
, Cardenas-Turanzas M, Pierce S, Nguyen KT,
Bueso-Ramos C
,
Kantarjian H
,
Garcia-Manero G
. Impact of comorbidities by ACE-27 in the revised-IPSS for patients with myelodysplastic syndromes. Am J Hematol. 2014 May; 89(5):509-16.
PMID:
24458781
; PMCID:
PMC4221257
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
Shah DR,
Daver N
,
Borthakur G
,
Hirsch-Ginsberg C
,
Oo TH
. Pernicious anemia with spuriously normal vitamin B12 level might be misdiagnosed as myelodysplastic syndrome. Clin Lymphoma Myeloma Leuk. 2014 Aug; 14(4):e141-3.
PMID:
24630920
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Geethakumari PR, Hoffmann MS,
Pemmaraju N
,
Hu S
,
Jorgensen JL
, O'Brien S,
Daver N
. Extramedullary B lymphoblastic leukemia/lymphoma (B-ALL/B-LBL): a diagnostic challenge. Clin Lymphoma Myeloma Leuk. 2014 Aug; 14(4):e115-8.
PMID:
24589157
; PMCID:
PMC4403758
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Nazha A,
Kantarjian HM
, Bhatt VR, Nogueras-Gonzalez G,
Cortes JE
,
Kadia T
,
Garcia-Manero G
, Abruzzo L,
Daver N
,
Pemmaraju N
, Quintas-Cardama A, Ravandi F, Keating M,
Borthakur G
. Prognostic implications of chromosome 17 abnormalities in the context of monosomal karyotype in patients with acute myeloid leukemia and complex cytogenetics. Clin Lymphoma Myeloma Leuk. 2014 Apr; 14(2):163-71.
PMID:
24461514
; PMCID:
PMC4167660
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jain P,
Kantarjian H
,
Patel K
, Faderl S,
Garcia-Manero G
, Benjamini O,
Borthakur G
,
Pemmaraju N
,
Kadia T
,
Daver N
, Nazha A,
Luthra R
, Pierce S,
Cortes J
, Ravandi F. Mutated NPM1 in patients with acute myeloid leukemia in remission and relapse. Leuk Lymphoma. 2014 Jun; 55(6):1337-44.
PMID:
24004182
; PMCID:
PMC4143910
.
Citations:
16
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Nazha A,
Kantarjian H
, Ravandi F,
Huang X
, Choi S,
Garcia-Manero G
,
Jabbour E
,
Borthakur G
,
Kadia T
,
Konopleva M
,
Cortes J
,
Ferrajoli A
,
Kornblau S
,
Daver N
,
Pemmaraju N
,
Andreeff M
,
Estrov Z
, Du M, Brandt M, Faderl S. Clofarabine, idarubicin, and cytarabine (CIA) as frontline therapy for patients =60 years with newly diagnosed acute myeloid leukemia. Am J Hematol. 2013 Nov; 88(11):961-6.
PMID:
23877926
; PMCID:
PMC4110914
.
Citations:
21
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Strati P,
Daver N
, Ravandi F,
Pemmaraju N
, Pierce S,
Garcia-Manero G
, Nazha A,
Kadia T
,
Jabbour E
,
Borthakur G
, Faderl S, Quintas-Cardama A,
Kantarjian H
,
Cortes J
. Biological and clinical features of trisomy 21 in adult patients with acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2013 Sep; 13 Suppl 2:S276-81.
PMID:
23969309
; PMCID:
PMC4101888
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
, Shastri A,
Kadia T
, Quintas-Cardama A,
Jabbour E
,
Konopleva M
, O'Brien S, Pierce S, Zhou L,
Cortes J
,
Kantarjian H
,
Verstovsek S
. Modest activity of pomalidomide in patients with myelofibrosis and significant anemia. Leuk Res. 2013 Nov; 37(11):1440-4.
PMID:
23890523
; PMCID:
PMC4232180
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Daver N
, Liu Dumlao T, Ravandi F, Pierce S,
Borthakur G
,
Pemmaraju N
, Nazha A, Faderl S,
Jabbour E
,
Garcia-Manero G
,
Cortes J
,
Kantarjian H
, Quint?s-Cardama A. Effect of NPM1 and FLT3 mutations on the outcomes of elderly patients with acute myeloid leukemia receiving standard chemotherapy. Clin Lymphoma Myeloma Leuk. 2013 Aug; 13(4):435-40.
PMID:
23763915
; PMCID:
PMC4114766
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
, O'Brien S. Novel therapeutic strategies in adult acute lymphoblastic leukemia--a focus on emerging monoclonal antibodies. Curr Hematol Malig Rep. 2013 Jun; 8(2):123-31.
PMID:
23539383
; PMCID:
PMC4438701
.
Citations:
10
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ravandi F, Alattar ML, Grunwald MR, Rudek MA, Rajkhowa T, Richie MA, Pierce S,
Daver N
,
Garcia-Manero G
, Faderl S, Nazha A,
Konopleva M
,
Borthakur G
,
Burger J
,
Kadia T
, Dellasala S,
Andreeff M
,
Cortes J
,
Kantarjian H
, Levis M. Phase 2 study of azacytidine plus sorafenib in patients with acute myeloid leukemia and FLT-3 internal tandem duplication mutation. Blood. 2013 Jun 06; 121(23):4655-62.
PMID:
23613521
; PMCID:
PMC3674666
.
Citations:
158
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Jabbour E
, Mathisen MS,
Garcia-Manero G
,
Champlin R
,
Popat U
,
Khouri I
, Giralt S,
Kadia T
, Chen J, Pierce S, Koca E,
Daver N
, Tanaka M,
Rondon G
,
Oran B
,
Parmar S
,
Kantarjian H
, de Lima M. Allogeneic hematopoietic stem cell transplantation versus hypomethylating agents in patients with myelodysplastic syndrome: a retrospective case-control study. Am J Hematol. 2013 Mar; 88(3):198-200.
PMID:
23345254
; PMCID:
PMC4085133
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Bhamidipati PK,
Jabbour E
,
Konoplev S
,
Estrov Z
,
Cortes J
,
Daver N
. Epstein-Barr virus-induced CD30-positive diffuse large B-cell lymphoma in a patient with mixed-phenotypic leukemia treated with clofarabine. Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):342-6.
PMID:
23246163
; PMCID:
PMC4019340
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Lee HJ
,
Daver N
,
Kantarjian HM
,
Verstovsek S
, Ravandi F. The role of JAK pathway dysregulation in the pathogenesis and treatment of acute myeloid leukemia. Clin Cancer Res. 2013 Jan 15; 19(2):327-35.
PMID:
23209034
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Daver N
, Strati P,
Jabbour E
,
Kadia T
,
Luthra R
,
Wang S
, Patel K, Ravandi F,
Cortes J
, Qin Dong X,
Kantarjian H
,
Garcia-Manero G
. FLT3 mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia. Am J Hematol. 2013 Jan; 88(1):56-9.
PMID:
23115106
; PMCID:
PMC4085099
.
Citations:
31
Fields:
Hem
Hematology
Translation:
Humans
Cells
Daver N
, Nazha A,
Kantarjian HM
, Haltom R, Ravandi F. Treatment of hairy cell leukemia during pregnancy: are purine analogues and rituximab viable therapeutic options. Clin Lymphoma Myeloma Leuk. 2013 Feb; 13(1):86-9.
PMID:
22981963
; PMCID:
PMC4084644
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Borthakur G
, Rosenblum MG, Talpaz M,
Daver N
, Ravandi F, Faderl S, Freireich EJ,
Kadia T
,
Garcia-Manero G
,
Kantarjian H
,
Cortes JE
. Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies. Haematologica. 2013 Feb; 98(2):217-21.
PMID:
22875630
; PMCID:
PMC3561428
.
Citations:
28
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Nazha A,
Cortes J
, Faderl S, Pierce S,
Daver N
,
Kadia T
,
Borthakur G
,
Luthra R
,
Kantarjian H
, Ravandi F. Activating internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD) at complete response and relapse in patients with acute myeloid leukemia. Haematologica. 2012 Aug; 97(8):1242-5.
PMID:
22532519
; PMCID:
PMC3409823
.
Citations:
19
Fields:
Hem
Hematology
Translation:
Humans
Cells
Daver N
,
Cortes J
. Molecular targeted therapy in acute myeloid leukemia. Hematology. 2012 Apr; 17 Suppl 1:S59-62.
PMID:
22507781
.