-
Nguyen CB, Reimers MA, Perera C, Abida W, Chou J, Feng FY, Antonarakis ES, McKay RR, Pachynski RK, Zhang J, Reichert ZR, Palmbos PL, Caram MEV, Vaishampayan UN, Heath EI, Hopkins AC, Cieslik MP, Wu YM, Robinson D, Baladandayuthapani V, Chinnaiyan AM, Alva AS, Nguyen CB, Reimers MA, Perera C, Abida W, Chou J, Feng FY, Antonarakis ES, McKay RR, Pachynski RK, Zhang J, Reichert ZR, Palmbos PL, Caram MEV, Vaishampayan UN, Heath EI, Hopkins AC, Cieslik MP, Wu YM, Robinson DR, Baladandayuthapani V, Chinnaiyan AM, Alva AS. Evaluating Immune Checkpoint Blockade in Metastatic Castration-Resistant Prostate Cancers with Deleterious CDK12 Alterations in the Phase 2 IMPACT Trial. Clin Cancer Res. 2024 Aug 01; 30(15):3200-3210.
PMID: 38787530; PMCID: PMC11293970.
Citations:
1 Fields:
Translation:
HumansCTClinical Trials
-
Whitehead CE, Ziemke EK, Frankowski-McGregor CL, Mumby RA, Chung J, Li J, Osher N, Coker O, Baladandayuthapani V, Kopetz S, Sebolt-Leopold JS. A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nat Cancer. 2024 Aug; 5(8):1250-1266.
PMID: 38992135; PMCID: PMC11357990.
Citations: Fields:
Translation:
HumansAnimalsCells
-
Zakharia Y, Singer EA, Acharyya S, Garje R, Joshi M, Peace D, Baladandayuthapani V, Majumdar A, Li X, Lalancette C, Kryczek I, Zou W, Alva A. Durvalumab and guadecitabine in advanced clear cell renal cell carcinoma: results from the phase Ib/II study BTCRC-GU16-043. Nat Commun. 2024 Feb 01; 15(1):972.
PMID: 38302476; PMCID: PMC10834488.
Citations:
1 Fields:
Translation:
HumansCTClinical Trials
-
Masotti M, Osher N, Eliason J, Rao A, Baladandayuthapani V. DIMPLE: An R package to quantify, visualize, and model spatial cellular interactions from multiplex imaging with distance matrices. Patterns (N Y). 2023 Dec 08; 4(12):100879.
PMID: 38106614; PMCID: PMC10724356.
-
Liu Q, Li G, Baladandayuthapani V. Pan-Cancer Drug Response Prediction Using Integrative Principal Component Regression. bioRxiv. 2023 Oct 05.
PMID: 37873111; PMCID: PMC10592913.
Citations:
-
Mohammed S, Kurtek S, Bharath K, Rao A, Baladandayuthapani V. Tumor radiogenomics in gliomas with Bayesian layered variable selection. Med Image Anal. 2023 12; 90:102964.
PMID: 37797481; PMCID: PMC10653647.
Citations: Fields:
Translation:
Humans
-
Yao TH, Wu Z, Bharath K, Li J, Baladandayuthapani V. PROBABILISTIC LEARNING OF TREATMENT TREES IN CANCER. Ann Appl Stat. 2023 Sep; 17(3):1884-1908.
PMID: 37711665; PMCID: PMC10501503.
Citations:
-
Masotti M, Osher N, Eliason J, Rao A, Baladandayuthapani V. DIMPLE: AN R PACKAGE TO QUANTIFY, VISUALIZE, AND MODEL SPATIAL CELLULAR INTERACTIONS FROM MULTIPLEX IMAGING WITH DISTANCE MATRICES. bioRxiv. 2023 Jul 22.
PMID: 37503048; PMCID: PMC10370183.
Citations:
-
Morikawa A, Li J, Ulintz P, Cheng X, Apfel A, Robinson D, Hopkins A, Kumar-Sinha C, Wu YM, Serhan H, Verbal K, Thomas D, Hayes DF, Chinnaiyan AM, Baladandayuthapani V, Heth J, Soellner MB, Merajver SD, Merrill N. Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response Assessment. Cancer Res Commun. 2023 06; 3(6):1093-1103.
PMID: 37377606; PMCID: PMC10284082.
Citations: Translation:
Humans
-
Osher N, Kang J, Krishnan S, Rao A, Baladandayuthapani V. SPARTIN: a Bayesian method for the quantification and characterization of cell type interactions in spatial pathology data. Front Genet. 2023; 14:1175603.
PMID: 37274781; PMCID: PMC10232864.
Citations:
-
Bhattacharyya R, Henderson N, Baladandayuthapani V. BaySyn: Bayesian Evidence Synthesis for Multi-system Multiomic Integration. Pac Symp Biocomput. 2023; 28:275-286.
PMID: 36540984; PMCID: PMC10652956.
Citations: Fields:
Translation:
Humans
-
Desai N, Morris JS, Baladandayuthapani V. NetCellMatch: Multiscale Network-Based Matching of Cancer Cell Lines to Patients Using Graphical Wavelets. Chem Biodivers. 2022 Dec; 19(12):e202200746.
PMID: 36279370; PMCID: PMC10066864.
Citations: Fields:
Translation:
HumansCells
-
Bhattacharyya R, Burman A, Singh K, Banerjee S, Maity S, Auddy A, Rout SK, Lahoti S, Panda R, Baladandayuthapani V. Role of multiresolution vulnerability indices in COVID-19 spread in India: a Bayesian model-based analysis. BMJ Open. 2022 11 17; 12(11):e056292.
PMID: 36396323; PMCID: PMC9676421.
Citations: Fields:
Translation:
HumansPHPublic Health
-
Acharyya S, Zhou X, Baladandayuthapani V. SpaceX: gene co-expression network estimation for spatial transcriptomics. Bioinformatics. 2022 11 15; 38(22):5033-5041.
PMID: 36179087; PMCID: PMC9665869.
Citations:
1 Fields:
Translation:
HumansAnimalsCells
-
Das P, Peterson CB, Ni Y, Reuben A, Zhang J, Zhang J, Do KA, Baladandayuthapani V. Bayesian hierarchical quantile regression with application to characterizing the immune architecture of lung cancer. Biometrics. 2023 09; 79(3):2474-2488.
PMID: 36239535; PMCID: PMC10102253.
Citations: Fields:
Translation:
Humans
-
Panigrahi S, Mohammed S, Rao A, Baladandayuthapani V. Integrative Bayesian models using Post-selective inference: A case study in radiogenomics. Biometrics. 2023 09; 79(3):1801-1813.
PMID: 35973786; PMCID: PMC9931934.
Citations:
-
Qazilbash MH, Saini NY, Cha SC, Wang Z, Stadtmauer EA, Baladandayuthapani V, Lin H, Tross B, Honhar M, Rao SS, Kim K, Popescu M, Szymura S, Zhang T, Anderson A, Bashir Q, Shpall EJ, Orlowski RZ, Levine BL, Kerr N, Garfall A, Cohen A, Vogl DT, Dengel K, June CH, Champlin R, Kwak LW. A randomized phase 2 trial of idiotype vaccination and adoptive autologous T-cell transfer in patients with multiple myeloma. Blood. 2022 03 03; 139(9):1289-1301.
PMID: 34521108; PMCID: PMC8900281.
-
Tanaka I, Dayde D, Tai MC, Mori H, Solis LM, Tripathi SC, Fahrmann JF, Unver N, Parhy G, Jain R, Parra ER, Murakami Y, Aguilar-Bonavides C, Mino B, Celiktas M, Dhillon D, Casabar JP, Nakatochi M, Stingo F, Baladandayuthapani V, Wang H, Katayama H, Dennison JB, Lorenzi PL, Do KA, Fujimoto J, Behrens C, Ostrin EJ, Rodriguez-Canales J, Hase T, Fukui T, Kajino T, Kato S, Yatabe Y, Hosoda W, Kawaguchi K, Yokoi K, Chen-Yoshikawa TF, Hasegawa Y, Gazdar AF, Wistuba II, Hanash S, Taguchi A. SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas. J Natl Cancer Inst. 2022 02 07; 114(2):290-301.
PMID: 34524427; PMCID: PMC8826620.
Citations:
2 Fields:
Translation:
HumansAnimals
-
Ni Y, Stingo FC, Baladandayuthapani V. Bayesian Covariate-Dependent Gaussian Graphical Models with Varying Structure. J Mach Learn Res. 2022; 23(242).
PMID: 37799290; PMCID: PMC10552903.
Citations:
-
Schellingerhout D, Jacobsen M, Le Roux L, Johnson J, Baladandayuthapani V, Hwang KP, Hazle J, Schomer D, Cody D. The Calcium Versus Hemorrhage Trial: Developing Diagnostic Criteria for Chronic Intracranial Susceptibility Lesions Using Single-Energy Computed Tomography, Dual-Energy Computed Tomography, and Quantitative Susceptibility Mapping. Invest Radiol. 2021 06 01; 56(6):385-393.
PMID: 33534507.
Citations:
1 Fields:
Translation:
Humans
-
Ni Y, Baladandayuthapani V, Vannucci M, Stingo FC. Bayesian graphical models for modern biological applications. Stat Methods Appt. 2022; 31(2):197-225.
PMID: 35673326; PMCID: PMC9165295.
Citations:
-
Gates EDH, Weinberg JS, Prabhu SS, Lin JS, Hamilton J, Hazle JD, Fuller GN, Baladandayuthapani V, Fuentes DT, Schellingerhout D. Estimating Local Cellular Density in Glioma Using MR Imaging Data. AJNR Am J Neuroradiol. 2021 01; 42(1):102-108.
PMID: 33243897; PMCID: PMC7814791.
Citations:
1 Fields:
Translation:
Humans
-
Ha MJ, Stingo FC, Baladandayuthapani V. Bayesian Structure Learning in Multi-layered Genomic Networks. J Am Stat Assoc. 2021; 116(534):605-618.
PMID: 34239216; PMCID: PMC8259335.
-
Ray D, Salvatore M, Bhattacharyya R, Wang L, Du J, Mohammed S, Purkayastha S, Halder A, Rix A, Barker D, Kleinsasser M, Zhou Y, Bose D, Song P, Banerjee M, Baladandayuthapani V, Ghosh P, Mukherjee B. Predictions, role of interventions and effects of a historic national lockdown in India's response to the COVID-19 pandemic: data science call to arms. Harv Data Sci Rev. 2020; 2020(Suppl 1).
PMID: 32607504; PMCID: PMC7326342.
-
Bhattacharyya R, Ha MJ, Liu Q, Akbani R, Liang H, Baladandayuthapani V. Personalized Network Modeling of the Pan-Cancer Patient and Cell Line Interactome. JCO Clin Cancer Inform. 2020 05; 4:399-411.
PMID: 32374631; PMCID: PMC7265783.
Citations:
4 Fields:
Translation:
HumansCells
-
Gates EDH, Lin JS, Weinberg JS, Prabhu SS, Hamilton J, Hazle JD, Fuller GN, Baladandayuthapani V, Fuentes DT, Schellingerhout D. Imaging-Based Algorithm for the Local Grading of Glioma. AJNR Am J Neuroradiol. 2020 03; 41(3):400-407.
PMID: 32029466; PMCID: PMC7077885.
Citations:
5 Fields:
Translation:
HumansCTClinical Trials
-
Das P, Peterson CB, Do KA, Akbani R, Baladandayuthapani V. NExUS: Bayesian simultaneous network estimation across unequal sample sizes. Bioinformatics. 2020 02 01; 36(3):798-804.
PMID: 31504175; PMCID: PMC8215919.
-
Reuben A, Zhang J, Chiou SH, Gittelman RM, Li J, Lee WC, Fujimoto J, Behrens C, Liu X, Wang F, Quek K, Wang C, Kheradmand F, Chen R, Chow CW, Lin H, Bernatchez C, Jalali A, Hu X, Wu CJ, Eterovic AK, Parra ER, Yusko E, Emerson R, Benzeno S, Vignali M, Wu X, Ye Y, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Cascone T, Snyder A, Wargo JA, Herbst R, Swisher S, Kadara H, Moran C, Kalhor N, Zhang J, Scheet P, Vaporciyan AA, Sepesi B, Gibbons DL, Robins H, Hwu P, Heymach JV, Sharma P, Allison JP, Baladandayuthapani V, Lee JJ, Davis MM, Wistuba II, Futreal PA, Zhang J. Comprehensive T cell repertoire characterization of non-small cell lung cancer. Nat Commun. 2020 01 30; 11(1):603.
PMID: 32001676; PMCID: PMC6992630.
Citations:
54 Fields:
Translation:
HumansCells
-
Liu Q, Ha MJ, Bhattacharyya R, Garmire L, Baladandayuthapani V. Network-Based Matching of Patients and Targeted Therapies for Precision Oncology. Pac Symp Biocomput. 2020; 25:623-634.
PMID: 31797633; PMCID: PMC7301202.
Citations: Fields:
Translation:
HumansCells
-
Guha N, Baladandayuthapani V, Mallick BK. Quantile Graphical Models: Bayesian Approaches. J Mach Learn Res. 2020; 21(79):1-47.
PMID: 34305477; PMCID: PMC8297664.
-
Zhang Y, Morris JS, Aerry SN, Rao AUK, Baladandayuthapani V. RADIO-IBAG: RADIOMICS-BASED INTEGRATIVE BAYESIAN ANALYSIS OF MULTIPLATFORM GENOMIC DATA. Ann Appl Stat. 2019; 13(3):1957-1988.
PMID: 33224404; PMCID: PMC7678720.
-
Maity AK, Bhattacharya A, Mallick BK, Baladandayuthapani V. Bayesian data integration and variable selection for pan-cancer survival prediction using protein expression data. Biometrics. 2020 03; 76(1):316-325.
PMID: 31393003; PMCID: PMC7007312.
Citations:
6 Fields:
Translation:
Humans
-
Manasanch EE, Han G, Mathur R, Qing Y, Zhang Z, Lee H, Weber DM, Amini B, Berkova Z, Eterovic K, Zhang S, Zhang J, Song X, Mao X, Morgan M, Feng L, Baladandayuthapani V, Futreal A, Wang L, Neelapu SS, Orlowski RZ. A pilot study of pembrolizumab in smoldering myeloma: report of the clinical, immune, and genomic analysis. Blood Adv. 2019 08 13; 3(15):2400-2408.
PMID: 31405950; PMCID: PMC6693011.
-
Yang H, Baladandayuthapani V, Rao AUK, Morris JS. Quantile Function on Scalar Regression Analysis for Distributional Data. J Am Stat Assoc. 2020; 115(529):90-106.
PMID: 32981991; PMCID: PMC7517594.
-
Marisetty AL, Lu L, Veo BL, Liu B, Coarfa C, Kamal MM, Kassem DH, Irshad K, Lu Y, Gumin J, Henry V, Paulucci-Holthauzen A, Rao G, Baladandayuthapani V, Lang FF, Fuller GN, Majumder S. REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis. Neuro Oncol. 2019 06 10; 21(6):775-785.
PMID: 30953587; PMCID: PMC6556851.
Citations:
7 Fields:
Translation:
HumansAnimalsCells
-
Citations:
12 Fields:
Translation:
HumansCTClinical Trials
-
Citations:
3 Fields:
Translation:
HumansCells
-
Ruder D, Papadimitrakopoulou V, Shien K, Behrens C, Kalhor N, Chen H, Shen L, Lee JJ, Hong WK, Tang X, Girard L, Minna JD, Diao L, Wang J, Mino B, Villalobos P, Rodriguez-Canales J, Hanson NE, Sun J, Miller V, Greenbowe J, Frampton G, Herbst RS, Baladandayuthapani V, Wistuba II, Izzo JG. Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer. Oncotarget. 2018 Sep 21; 9(74):33995-34008.
PMID: 30338041; PMCID: PMC6188056.
-
Banerjee S, Akbani R, Baladandayuthapani V. Spectral Clustering via sparse graph structure learning with application to Proteomic Signaling Networks in Cancer. Comput Stat Data Anal. 2019 Apr; 132:46-69.
PMID: 38774121; PMCID: PMC11106846.
Citations:
-
Ni H, Shirazi F, Baladandayuthapani V, Lin H, Kuiatse I, Wang H, Jones RJ, Berkova Z, Hitoshi Y, Ansell SM, Treon SP, Thomas SK, Lee HC, Wang Z, Davis RE, Orlowski RZ. Targeting Myddosome Signaling in Waldenstr?m's Macroglobulinemia with the Interleukin-1 Receptor-Associated Kinase 1/4 Inhibitor R191. Clin Cancer Res. 2018 12 15; 24(24):6408-6420.
PMID: 30126942; PMCID: PMC6295253.
Citations:
6 Fields:
Translation:
HumansAnimalsCells
-
Elhalawani H, Lin TA, Volpe S, Mohamed ASR, White AL, Zafereo J, Wong AJ, Berends JE, AboHashem S, Williams B, Aymard JM, Kanwar A, Perni S, Rock CD, Cooksey L, Campbell S, Yang P, Nguyen K, Ger RB, Cardenas CE, Fave XJ, Liu R, Huang C, Yu K, Li T, Yu Y, Zhang Y, Zhu H, Morris JS, Baladandayuthapani V, Shumway JW, Ghosh A, Phoulady HA, Goyal V, Canahuate G, Marai GE, Vock D, Lai SY, Mackin DS, Court LE, Freymann J, Farahani K, Kaplathy-Cramer J, Fuller CD, Sansone C, Piantadosi G, Marrone S, P?hlmann A. Machine Learning Applications in Head and Neck Radiation Oncology: Lessons From Open-Source Radiomics Challenges. Front Oncol. 2018; 8:294.
PMID: 30175071; PMCID: PMC6107800.
-
Ni Y, Stingo FC, Ha MJ, Akbani R, Baladandayuthapani V. Bayesian Hierarchical Varying-sparsity Regression Models with Application to Cancer Proteogenomics. J Am Stat Assoc. 2019; 114(525):48-60.
PMID: 31178611; PMCID: PMC6552682.
-
Lee W, Miranda MF, Baladandayuthapani V, Fazio M, Downs JC, Morris JS, Rausch P. Bayesian Semiparametric Functional Mixed Models for Serially Correlated Functional Data, with Application to Glaucoma Data. J Am Stat Assoc. 2019; 114(526):495-513.
PMID: 31235987; PMCID: PMC6590079.
-
Kundu S, Cheng Y, Shin M, Manyam G, Mallick BK, Baladandayuthapani V. Bayesian variable selection with graphical structure learning: Applications in integrative genomics. PLoS One. 2018; 13(7):e0195070.
PMID: 30059495; PMCID: PMC6066211.
Citations:
2 Fields:
Translation:
HumansCells
-
Zinn PO, Singh SK, Kotrotsou A, Hassan I, Thomas G, Luedi MM, Elakkad A, Elshafeey N, Idris T, Mosley J, Gumin J, Fuller GN, de Groot JF, Baladandayuthapani V, Sulman EP, Kumar AJ, Sawaya R, Lang FF, Piwnica-Worms D, Colen RR. A Coclinical Radiogenomic Validation Study: Conserved Magnetic Resonance Radiomic Appearance of Periostin-Expressing Glioblastoma in Patients and Xenograft Models. Clin Cancer Res. 2018 12 15; 24(24):6288-6299.
PMID: 30054278; PMCID: PMC6538261.
Citations:
37 Fields:
Translation:
HumansAnimals
-
Ni Y, Stingo FC, Baladandayuthapani V. Bayesian Graphical Regression. J Am Stat Assoc. 2019; 114(525):184-197.
PMID: 36937091; PMCID: PMC10021014.
-
Kappadath SC, Mikell J, Balagopal A, Baladandayuthapani V, Kaseb A, Mahvash A. Hepatocellular Carcinoma Tumor Dose Response After 90Y-radioembolization With Glass Microspheres Using 90Y-SPECT/CT-Based Voxel Dosimetry. Int J Radiat Oncol Biol Phys. 2018 10 01; 102(2):451-461.
PMID: 30191875.
Citations:
25 Fields:
Translation:
Humans
-
Davenport CA, Maity A, Baladandayuthapani V. Functional interaction-based nonlinear models with application to multiplatform genomics data. Stat Med. 2018 08 15; 37(18):2715-2733.
PMID: 29737021; PMCID: PMC6031473.
Citations: Fields:
Translation:
Humans
-
Class CA, Ha MJ, Baladandayuthapani V, Do KA. iDINGO-integrative differential network analysis in genomics with Shiny application. Bioinformatics. 2018 04 01; 34(7):1243-1245.
PMID: 29194470; PMCID: PMC6030922.
Citations:
4 Fields:
Translation:
Humans
-
Zhang X, Lee HC, Shirazi F, Baladandayuthapani V, Lin H, Kuiatse I, Wang H, Jones RJ, Berkova Z, Singh RK, Lu J, Qian Y, Raina K, Coleman KG, Crews CM, Li B, Wang H, Hailemichael Y, Thomas SK, Wang Z, Davis RE, Orlowski RZ. Protein targeting chimeric molecules specific for bromodomain and extra-terminal motif family proteins are active against pre-clinical models of multiple myeloma. Leukemia. 2018 10; 32(10):2224-2239.
PMID: 29581547; PMCID: PMC6160356.
Citations:
29 Fields:
Translation:
HumansAnimalsCells
-
Bharath K, Kurtek S, Rao A, Baladandayuthapani V. Radiologic image-based statistical shape analysis of brain tumours. J R Stat Soc Ser C Appl Stat. 2018 Nov; 67(5):1357-1378.
PMID: 30420787; PMCID: PMC6225782.
-
Meraz IM, Majidi M, Cao X, Lin H, Li L, Wang J, Baladandayuthapani V, Rice D, Sepesi B, Ji L, Roth JA. TUSC2 Immunogene Therapy Synergizes with Anti-PD-1 through Enhanced Proliferation and Infiltration of Natural Killer Cells in Syngeneic Kras-Mutant Mouse Lung Cancer Models. Cancer Immunol Res. 2018 02; 6(2):163-177.
PMID: 29339375; PMCID: PMC5909977.
Citations:
12 Fields:
Translation:
HumansAnimalsCells
-
Shoemaker K, Hobbs BP, Bharath K, Ng CS, Baladandayuthapani V. Tree-based Methods for Characterizing Tumor Density Heterogeneity. Pac Symp Biocomput. 2018; 23:216-227.
PMID: 29218883; PMCID: PMC5749399.
Citations:
5 Fields:
Translation:
Humans
-
Wang H, Baladandayuthapani V, Wang Z, Lin H, Berkova Z, Davis RE, Yang L, Orlowski RZ. Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma. Oncotarget. 2017 Dec 26; 8(69):113858-113873.
PMID: 29371952; PMCID: PMC5768369.
-
Zhu B, Song N, Shen R, Arora A, Machiela MJ, Song L, Landi MT, Ghosh D, Chatterjee N, Baladandayuthapani V, Zhao H. Integrating Clinical and Multiple Omics Data for Prognostic Assessment across Human Cancers. Sci Rep. 2017 12 05; 7(1):16954.
PMID: 29209073; PMCID: PMC5717223.
Citations:
31 Fields:
Translation:
HumansCells
-
Yu K, Zhang Y, Yu Y, Huang C, Liu R, Li T, Yang L, Morris JS, Baladandayuthapani V, Zhu H. Radiomic analysis in prediction of Human Papilloma Virus status. Clin Transl Radiat Oncol. 2017 Dec; 7:49-54.
PMID: 29594229; PMCID: PMC5862639.
-
Morris JS, Baladandayuthapani V. Rejoinder to statistical contributions to bioinformatics: Design, modelling, structure learning and Integration. Stat Modelling. 2017 Aug; 17(4-5):338-357.
PMID: 30034293; PMCID: PMC6052864.
Citations:
-
Bharath K, Kambadur P, Dey DK, Rao A, Baladandayuthapani V. STATISTICAL TESTS FOR LARGE TREE-STRUCTURED DATA. J Am Stat Assoc. 2017; 112(520):1733-1743.
PMID: 37013199; PMCID: PMC10066867.
Citations:
-
Wadhwa R, Wang X, Baladandayuthapani V, Liu B, Shiozaki H, Shimodaira Y, Lin Q, Elimova E, Hofstetter WL, Swisher SG, Rice DC, Maru DM, Kalhor N, Bhutani MS, Weston B, Lee JH, Skinner HD, Scott AW, Kaya DM, Harada K, Berry D, Song S, Ajani JA. Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients. Br J Cancer. 2017 Aug 22; 117(5):648-655.
PMID: 28728163; PMCID: PMC5572179.
Citations:
13 Fields:
Translation:
HumansCells
-
Gentile E, Oba T, Lin J, Shao R, Meng F, Cao X, Lin HY, Mourad M, Pataer A, Baladandayuthapani V, Cai D, Roth JA, Ji L. Cationic liquid crystalline nanoparticles for the delivery of synthetic RNAi-based therapeutics. Oncotarget. 2017 Jul 18; 8(29):48222-48239.
PMID: 28637023; PMCID: PMC5564640.
Citations:
2 Fields:
Translation:
HumansAnimalsCells
-
Morris JS, Baladandayuthapani V. Statistical Contributions to Bioinformatics: Design, Modeling, Structure Learning, and Integration. Stat Modelling. 2017; 17(4-5):245-289.
PMID: 29129969; PMCID: PMC5679480.
-
Ye X, Wang R, Bhattacharya R, Boulbes DR, Fan F, Xia L, Adoni H, Ajami NJ, Wong MC, Smith DP, Petrosino JF, Venable S, Qiao W, Baladandayuthapani V, Maru D, Ellis LM. Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors. Cancer Prev Res (Phila). 2017 Jul; 10(7):398-409.
PMID: 28483840.
Citations:
45 Fields:
Translation:
HumansCells
-
Zhang Y, Linder MH, Shojaie A, Ouyang Z, Shen R, Baggerly KA, Baladandayuthapani V, Zhao H. Dissecting Pathway Disturbances Using Network Topology and Multi-platform Genomics Data. Stat Biosci. 2018 Apr; 10(1):86-106.
PMID: 37388623; PMCID: PMC10309155.
-
Bhadra A, Rao A, Baladandayuthapani V. Inferring network structure in non-normal and mixed discrete-continuous genomic data. Biometrics. 2018 03; 74(1):185-195.
PMID: 28437848; PMCID: PMC5654714.
Citations:
6 Fields:
Translation:
Humans
-
Lee HC, Wang H, Baladandayuthapani V, Lin H, He J, Jones RJ, Kuiatse I, Gu D, Wang Z, Ma W, Lim J, O'Brien S, Keats J, Yang J, Davis RE, Orlowski RZ. RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma. Br J Haematol. 2017 04; 177(1):80-94.
PMID: 28369725; PMCID: PMC5695568.
Citations:
22 Fields:
Translation:
HumansAnimalsCells
-
Baljevic M, Zaman S, Baladandayuthapani V, Lin YH, de Partovi CM, Berkova Z, Amini B, Thomas SK, Shah JJ, Weber DM, Fu M, Cleeland CS, Wang XS, Stellrecht CM, Davis RE, Gandhi V, Orlowski RZ. Phase II study of the c-MET inhibitor tivantinib (ARQ 197) in patients with relapsed or relapsed/refractory multiple myeloma. Ann Hematol. 2017 Jun; 96(6):977-985.
PMID: 28337527; PMCID: PMC5406425.
Citations:
7 Fields:
Translation:
HumansCTClinical Trials
-
Citations:
8 Fields:
Translation:
Humans
-
Xiaobo C, Majidi M, Feng M, Shao R, Wang J, Zhao Y, Baladandayuthapani V, Song J, Fang B, Ji L, Mehran R, Roth JA. TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin. Sci Rep. 2016 11 15; 6:35741.
PMID: 27845352; PMCID: PMC5109231.
Citations:
10 Fields:
Translation:
HumansCells
-
Roszik J, Haydu LE, Hess KR, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC, Baladandayuthapani V, Tetzlaff MT, Wargo JA, Chen K, Haymaker CL, Chen JQ, Meric-Bernstam F, Eterovic AK, Shaw KR, Mills GB, Gershenwald JE, Radvanyi LG, Hwu P, Futreal PA, Gibbons DL, Lazar AJ, Bernatchez C, Davies MA, Woodman SE, Forget MA. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Med. 2016 10 25; 14(1):168.
PMID: 27776519; PMCID: PMC5078889.
Citations:
64 Fields:
Translation:
HumansCells
-
Phillip CJ, Zaman S, Shentu S, Balakrishnan K, Zhang J, Baladandayuthapani V, Taverna P, Redkar S, Wang M, Stellrecht CM, Gandhi V. Erratum to: Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines. J Hematol Oncol. 2016 10 13; 9(1):110.
PMID: 27737688; PMCID: PMC5064904.
-
Kim S, Baladandayuthapani V, Lee JJ. Prediction-Oriented Marker Selection (PROMISE): With Application to High-Dimensional Regression. Stat Biosci. 2017 Jun; 9(1):217-245.
PMID: 28785367; PMCID: PMC5543994.
-
Bock F, Lu G, Srour SA, Gaballa S, Lin HY, Baladandayuthapani V, Honhar M, Stich M, Shah ND, Bashir Q, Patel K, Popat U, Hosing C, Korbling M, Delgado R, Rondon G, Shah JJ, Thomas SK, Manasanch EE, Isermann B, Orlowski RZ, Champlin RE, Qazilbash MH. Outcome of Patients with Multiple Myeloma and CKS1B Gene Amplification after Autologous Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 12; 22(12):2159-2164.
PMID: 27638366; PMCID: PMC5911156.
Citations:
8 Fields:
Translation:
HumansCells
-
Zhang L, Baladandayuthapani V, Zhu H, Baggerly KA, Majewski T, Czerniak BA, Morris JS. Functional CAR models for large spatially correlated functional datasets. J Am Stat Assoc. 2016; 111(514):772-786.
PMID: 28018013; PMCID: PMC5176110.
-
Nieto-Barajas L, Ji Y, Baladandayuthapani V. A semiparametric Bayesian model for comparing DNA copy numbers. Braz J Probab Stat. 2016 Aug; 30(3):345-365.
PMID: 37799327; PMCID: PMC10552905.
Citations:
-
Mikell JK, Mahvash A, Siman W, Baladandayuthapani V, Mourtada F, Kappadath SC. Selective Internal Radiation Therapy With Yttrium-90 Glass Microspheres: Biases and Uncertainties in Absorbed Dose Calculations Between Clinical Dosimetry Models. Int J Radiat Oncol Biol Phys. 2016 11 15; 96(4):888-896.
PMID: 27623307; PMCID: PMC5085875.
Citations:
9 Fields:
Translation:
Humans
-
Azadeh S, Hobbs BP, Ma L, Nielsen DA, Moeller FG, Baladandayuthapani V. INTEGRATIVE BAYESIAN ANALYSIS OF NEUROIMAGING-GENETIC DATA THROUGH HIERARCHICAL DIMENSION REDUCTION. Proc IEEE Int Symp Biomed Imaging. 2016 Apr; 2016:824-828.
PMID: 27917260; PMCID: PMC5129839.
-
Jones RJ, Iempridee T, Wang X, Lee HC, Mertz JE, Kenney SC, Lin HC, Baladandayuthapani V, Dawson CW, Shah JJ, Weber DM, Orlowski RZ. Lenalidomide, Thalidomide, and Pomalidomide Reactivate the Epstein-Barr Virus Lytic Cycle through Phosphoinositide 3-Kinase Signaling and Ikaros Expression. Clin Cancer Res. 2016 Oct 01; 22(19):4901-4912.
PMID: 27297582; PMCID: PMC5050094.
Citations:
20 Fields:
Translation:
HumansAnimalsCells
-
Saha A, Banerjee S, Kurtek S, Narang S, Lee J, Rao G, Martinez J, Bharath K, Rao AU, Baladandayuthapani V. DEMARCATE: Density-based magnetic resonance image clustering for assessing tumor heterogeneity in cancer. Neuroimage Clin. 2016; 12:132-43.
PMID: 27408798; PMCID: PMC4932621.
Citations:
4 Fields:
Translation:
Humans
-
Zhang XD, Baladandayuthapani V, Lin H, Mulligan G, Li B, Esseltine DW, Qi L, Xu J, Hunziker W, Barlogie B, Usmani SZ, Zhang Q, Crowley J, Hoering A, Shah JJ, Weber DM, Manasanch EE, Thomas SK, Li BZ, Wang HH, Zhang J, Kuiatse I, Tang JL, Wang H, He J, Yang J, Ma WC, Wang ZQ, Davis RE, Yang L, Orlowski RZ, Milan E, Cenci S. Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling. Cancer Cell. 2016 05 09; 29(5):639-652.
PMID: 27132469; PMCID: PMC4983190.
Citations:
46 Fields:
Translation:
HumansAnimalsCells
-
Zoh RS, Mallick B, Ivanov I, Baladandayuthapani V, Manyam G, Chapkin RS, Lampe JW, Carroll RJ. PCAN: Probabilistic correlation analysis of two non-normal data sets. Biometrics. 2016 12; 72(4):1358-1368.
PMID: 27037601; PMCID: PMC5045754.
Citations:
2 Fields:
Translation:
Humans
-
Sathyan P, Zinn PO, Marisetty AL, Liu B, Kamal MM, Singh SK, Bady P, Lu L, Wani KM, Veo BL, Gumin J, Kassem DH, Robinson F, Weng C, Baladandayuthapani V, Suki D, Colman H, Bhat KP, Sulman EP, Aldape K, Colen RR, Verhaak RG, Lu Z, Fuller GN, Huang S, Lang FF, Sawaya R, Hegi M, Majumder S. Mir-21-Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic Impact. J Neurosci. 2015 Nov 11; 35(45):15097-112.
PMID: 26558781; PMCID: PMC4642241.
Citations:
32 Fields:
Translation:
HumansAnimalsCells
-
Azadeh S, Hobbs BP, Ma L, Nielsen DA, Gerard Moeller F, Baladandayuthapani V. Integrative Bayesian analysis of neuroimaging-genetic data with application to cocaine dependence. Neuroimage. 2016 Jan 15; 125:813-824.
PMID: 26484829; PMCID: PMC5042574.
Citations:
3 Fields:
Translation:
Humans
-
Zhang S, Lu Z, Mao W, Ahmed AA, Yang H, Zhou J, Jennings N, Rodriguez-Aguayo C, Lopez-Berestein G, Miranda R, Qiao W, Baladandayuthapani V, Li Z, Sood AK, Liu J, Le XF, Bast RC. CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis. PLoS One. 2015; 10(7):e0131833.
PMID: 26146988; PMCID: PMC4492679.
Citations:
13 Fields:
Translation:
HumansAnimalsCells
-
Ha MJ, Baladandayuthapani V, Do KA. DINGO: differential network analysis in genomics. Bioinformatics. 2015 Nov 01; 31(21):3413-20.
PMID: 26148744; PMCID: PMC4751246.
Citations:
36 Fields:
Translation:
HumansCells
-
Dai B, Yan S, Lara-Guerra H, Kawashima H, Sakai R, Jayachandran G, Majidi M, Mehran R, Wang J, Bekele BN, Baladandayuthapani V, Yoo SY, Wang Y, Ying J, Meng F, Ji L, Roth JA. Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathways Resulting in Enhanced Therapeutic Efficacy. PLoS One. 2015; 10(6):e0123967.
PMID: 26053020; PMCID: PMC4460038.
Citations:
16 Fields:
Translation:
HumansAnimalsCells
-
Wait JM, Cody D, Jones AK, Rong J, Baladandayuthapani V, Kappadath SC. Performance Evaluation of Material Decomposition With Rapid-Kilovoltage-Switching Dual-Energy CT and Implications for Assessing Bone Mineral Density. AJR Am J Roentgenol. 2015 Jun; 204(6):1234-41.
PMID: 26001233.
Citations:
7 Fields:
Translation:
Humans
-
Gregory KB, Carroll RJ, Baladandayuthapani V, Lahiri SN. A Two-Sample Test for Equality of Means in High Dimension. J Am Stat Assoc. 2015 Jun 01; 110(510):837-849.
PMID: 26279594; PMCID: PMC4533933.
-
Ni Y, Stingo FC, Baladandayuthapani V. Bayesian nonlinear model selection for gene regulatory networks. Biometrics. 2015 Sep; 71(3):585-95.
PMID: 25854759; PMCID: PMC4575256.
Citations:
7 Fields:
Translation:
HumansCells
-
Kuiatse I, Baladandayuthapani V, Lin HY, Thomas SK, Bjorklund CC, Weber DM, Wang M, Shah JJ, Zhang XD, Jones RJ, Ansell SM, Yang G, Treon SP, Orlowski RZ. Targeting the Spleen Tyrosine Kinase with Fostamatinib as a Strategy against Waldenstr?m Macroglobulinemia. Clin Cancer Res. 2015 Jun 01; 21(11):2538-45.
PMID: 25748087; PMCID: PMC4737551.
Citations:
10 Fields:
Translation:
HumansCells
-
Ha MJ, Baladandayuthapani V, Do KA. Prognostic gene signature identification using causal structure learning: applications in kidney cancer. Cancer Inform. 2015; 14(Suppl 1):23-35.
PMID: 25861215; PMCID: PMC4362630.
-
Le Roux L, Chandler AG, Baladandayuthapani V, Schellingerhout D, Cody DD, Nute JL. Differentiation of low-attenuation intracranial hemorrhage and calcification using dual-energy computed tomography in a phantom system. Invest Radiol. 2015 Jan; 50(1):9-16.
PMID: 25162534; PMCID: PMC4335714.
Citations:
6 Fields:
Translation:
Humans
-
Zhang L, Morris JS, Zhang J, Orlowski RZ, Baladandayuthapani V. Bayesian joint selection of genes and pathways: applications in multiple myeloma genomics. Cancer Inform. 2014; 13(Suppl 2):113-23.
PMID: 25520554; PMCID: PMC4260770.
-
Fowler NH, Davis RE, Rawal S, Nastoupil L, Hagemeister FB, McLaughlin P, Kwak LW, Romaguera JE, Fanale MA, Fayad LE, Westin JR, Shah J, Orlowski RZ, Wang M, Turturro F, Oki Y, Claret LC, Feng L, Baladandayuthapani V, Muzzafar T, Tsai KY, Samaniego F, Neelapu SS. Safety and activity of lenalidomide and rituximab in untreated indolent lymphoma: an open-label, phase 2 trial. Lancet Oncol. 2014 Nov; 15(12):1311-8.
PMID: 25439689; PMCID: PMC4370362.
Citations:
89 Fields:
Translation:
HumansCTClinical Trials
-
Guha S, Ji Y, Baladandayuthapani V. Bayesian disease classification using copy number data. Cancer Inform. 2014; 13(Suppl 2):83-91.
PMID: 25336897; PMCID: PMC4196891.
-
Ordonez C, Garcia-Alvarado C, Baladandayuthapani V. Bayesian Variable Selection in Linear Regression in One Pass for Large Data Sets. ACM Trans Knowl Discov Data. 2014 Oct; 9(1).
PMID: 37012970; PMCID: PMC10066866.
Citations:
-
Jiang H, An L, Baladandayuthapani V, Auer PL. Classification, predictive modelling, and statistical analysis of cancer data (a). Cancer Inform. 2014; 13(Suppl 2):1-3.
PMID: 25288874; PMCID: PMC4179642.
Citations:
-
Ni Y, Stingo FC, Baladandayuthapani V. Integrative bayesian network analysis of genomic data. Cancer Inform. 2014; 13(Suppl 2):39-48.
PMID: 25288878; PMCID: PMC4179606.
-
Zhang L, Baladandayuthapani V, Mallick BK, Manyam GC, Thompson PA, Bondy ML, Do KA. Bayesian hierarchical structured variable selection methods with application to MIP studies in breast cancer. J R Stat Soc Ser C Appl Stat. 2014 Aug; 63(4):595-620.
PMID: 25705056; PMCID: PMC4334391.
-
Pemmaraju N, Shah D, Kantarjian H, Orlowski RZ, Baladandayuthapani V, Jain N, Wagner V, Garcia-Manero G, Shah J, Ravandi F, Pierce S, Takahashi K, Daver N, Nazha A, Verstovsek S, Jabbour E, De Lima M, Champlin R, Cortes J, Qazilbash MH, Nogueras Gonz?lez GM. Characteristics and outcomes of patients with multiple myeloma who develop therapy-related myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015 Feb; 15(2):110-4.
PMID: 25107338; PMCID: PMC4294996.
Citations:
15 Fields:
Translation:
Humans
-
Wu W, Merriman K, Nabaah A, Seval N, Seval D, Lin H, Wang M, Qazilbash MH, Baladandayuthapani V, Berry D, Orlowski RZ, Lee MH, Yeung SC. The association of diabetes and anti-diabetic medications with clinical outcomes in multiple myeloma. Br J Cancer. 2014 Jul 29; 111(3):628-36.
PMID: 24921909; PMCID: PMC4119980.
Citations:
24 Fields:
Translation:
Humans
-
Gregory KB, Momin AA, Coombes KR, Baladandayuthapani V. Latent Feature Decompositions for Integrative Analysis of Multi-Platform Genomic Data. IEEE/ACM Trans Comput Biol Bioinform. 2014 Nov-Dec; 11(6):984-94.
PMID: 26146492; PMCID: PMC4486317.
-
Voo KS, Foglietta M, Percivalle E, Chu F, Nattamai D, Harline M, Lee ST, Bover L, Lin HY, Baladandayuthapani V, Delgado D, Luong A, Davis RE, Kwak LW, Liu YJ, Neelapu SS. Selective targeting of Toll-like receptors and OX40 inhibit regulatory T-cell function in follicular lymphoma. Int J Cancer. 2014 Dec 15; 135(12):2834-46.
PMID: 24771328; PMCID: PMC4352105.
Citations:
13 Fields:
Translation:
HumansCells
-
El-Mabhouh AA, Ayres ML, Shpall EJ, Baladandayuthapani V, Keating MJ, Wierda WG, Gandhi V. Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells. Blood. 2014 Jun 12; 123(24):3780-9.
PMID: 24747434; PMCID: PMC4055925.
Citations:
13 Fields:
Translation:
HumansCells
-
Talluri R, Baladandayuthapani V, Mallick BK. Bayesian sparse graphical models and their mixtures. Stat. 2014 Jan 01; 3(1):109-125.
PMID: 24948842; PMCID: PMC4059614.
-
Baladandayuthapani V, Talluri R, Ji Y, Coombes KR, Lu Y, Hennessy BT, Davies MA, Mallick BK. BAYESIAN SPARSE GRAPHICAL MODELS FOR CLASSIFICATION WITH APPLICATION TO PROTEIN EXPRESSION DATA. Ann Appl Stat. 2014; 8(3):1443-1468.
PMID: 26246866; PMCID: PMC4523298.
-
Westin JR, Chu F, Zhang M, Fayad LE, Kwak LW, Fowler N, Romaguera J, Hagemeister F, Fanale M, Samaniego F, Feng L, Baladandayuthapani V, Wang Z, Ma W, Gao Y, Wallace M, Vence LM, Radvanyi L, Muzzafar T, Rotem-Yehudar R, Davis RE, Neelapu SS. Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial. Lancet Oncol. 2014 Jan; 15(1):69-77.
PMID: 24332512; PMCID: PMC3922714.
Citations:
225 Fields:
Translation:
HumansCTClinical Trials
-
Phillip CJ, Zaman S, Shentu S, Balakrishnan K, Zhang J, Baladandayuthapani V, Taverna P, Redkar S, Wang M, Stellrecht CM, Gandhi V. Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines. J Hematol Oncol. 2013 Dec 10; 6:92.
PMID: 24326130; PMCID: PMC3878866.
Citations:
11 Fields:
Translation:
HumansCells
-
Bhadra A, Baladandayuthapani V. Integrative Sparse Bayesian Analysis of High-dimensional Multi-platform Genomic Data in Glioblastoma. IEEE Int Workshop Genomic Signal Process Stat. 2013 Nov; 2013:1-4.
PMID: 37016713; PMCID: PMC10068898.
Citations:
-
Olivares RJ, Rao A, Morris JS, Baladandayuthapani V. Integrative Analysis of Multi-modal Correlated Imaging-Genomics Data in Glioblastoma. IEEE Int Workshop Genomic Signal Process Stat. 2013 Nov; 2013:5-8.
PMID: 37016714; PMCID: PMC10068897.
Citations:
-
Bailey AM, Zhan L, Maru D, Shureiqi I, Pickering CR, Kiriakova G, Izzo J, He N, Wei C, Baladandayuthapani V, Liang H, Kopetz S, Powis G, Guo GL. FXR silencing in human colon cancer by DNA methylation and KRAS signaling. Am J Physiol Gastrointest Liver Physiol. 2014 Jan 01; 306(1):G48-58.
PMID: 24177031; PMCID: PMC3920083.
Citations:
35 Fields:
Translation:
HumansCells
-
Ajani JA, Wang X, Song S, Suzuki A, Taketa T, Sudo K, Wadhwa R, Hofstetter WL, Komaki R, Maru DM, Lee JH, Bhutani MS, Weston B, Baladandayuthapani V, Yao Y, Honjo S, Scott AW, Skinner HD, Johnson RL, Berry D. ALDH-1 expression levels predict response or resistance to preoperative chemoradiation in resectable esophageal cancer patients. Mol Oncol. 2014 Feb; 8(1):142-9.
PMID: 24210755; PMCID: PMC3946849.
Citations:
55 Fields:
Translation:
HumansCells
-
Wang W, Baladandayuthapani V, Holmes CC, Do KA. Integrative network-based Bayesian analysis of diverse genomics data. BMC Bioinformatics. 2013; 14 Suppl 13:S8.
PMID: 24267288; PMCID: PMC3849715.
Citations:
8 Fields:
Translation:
Humans
-
Jennings EM, Morris JS, Carroll RJ, Manyam GC, Baladandayuthapani V. Bayesian methods for expression-based integration of various types of genomics data. EURASIP J Bioinform Syst Biol. 2013 Sep 21; 2013(1):13.
PMID: 24053265; PMCID: PMC3849593.
-
Srivastava S, Wang W, Manyam G, Ordonez C, Baladandayuthapani V. Integrating multi-platform genomic data using hierarchical Bayesian relevance vector machines. EURASIP J Bioinform Syst Biol. 2013 Jun 28; 2013(1):9.
PMID: 23809014; PMCID: PMC3726335.
-
Bjorklund CC, Baladandayuthapani V, Lin HY, Jones RJ, Kuiatse I, Wang H, Yang J, Shah JJ, Thomas SK, Wang M, Weber DM, Orlowski RZ. Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications. Leukemia. 2014 Feb; 28(2):373-83.
PMID: 23760401; PMCID: PMC3874423.
Citations:
50 Fields:
Translation:
HumansAnimalsCells
-
Pemmaraju N, Tanaka MF, Ravandi F, Lin H, Baladandayuthapani V, Rondon G, Giralt SA, Chen J, Pierce S, Cortes J, Kantarjian H, Champlin RE, De Lima M, Qazilbash MH. Outcomes in patients with relapsed or refractory acute promyelocytic leukemia treated with or without autologous or allogeneic hematopoietic stem cell transplantation. Clin Lymphoma Myeloma Leuk. 2013 Aug; 13(4):485-92.
PMID: 23769669; PMCID: PMC4112369.
Citations:
11 Fields:
Translation:
Humans
-
Rawal S, Chu F, Zhang M, Park HJ, Nattamai D, Kannan S, Sharma R, Delgado D, Chou T, Lin HY, Baladandayuthapani V, Luong A, Vega F, Fowler N, Dong C, Davis RE, Neelapu SS. Cross talk between follicular Th cells and tumor cells in human follicular lymphoma promotes immune evasion in the tumor microenvironment. J Immunol. 2013 Jun 15; 190(12):6681-93.
PMID: 23686488; PMCID: PMC3680117.
Citations:
38 Fields:
Translation:
HumansCells
-
Wang W, Baladandayuthapani V, Morris JS, Broom BM, Manyam G, Do KA. iBAG: integrative Bayesian analysis of high-dimensional multiplatform genomics data. Bioinformatics. 2013 Jan 15; 29(2):149-59.
PMID: 23142963; PMCID: PMC3546799.
Citations:
67 Fields:
Translation:
HumansCells
-
Kuhn DJ, Berkova Z, Jones RJ, Woessner R, Bjorklund CC, Ma W, Davis RE, Lin P, Wang H, Madden TL, Wei C, Baladandayuthapani V, Wang M, Thomas SK, Shah JJ, Weber DM, Orlowski RZ. Targeting the insulin-like growth factor-1 receptor to overcome bortezomib resistance in preclinical models of multiple myeloma. Blood. 2012 Oct 18; 120(16):3260-70.
PMID: 22932796; PMCID: PMC3476538.
Citations:
88 Fields:
Translation:
HumansAnimalsCells
-
Jones RJ, Bjorklund CC, Baladandayuthapani V, Kuhn DJ, Orlowski RZ. Drug resistance to inhibitors of the human double minute-2 E3 ligase is mediated by point mutations of p53, but can be overcome with the p53 targeting agent RITA. Mol Cancer Ther. 2012 Oct; 11(10):2243-53.
PMID: 22933706; PMCID: PMC3469746.
Citations:
29 Fields:
Translation:
HumansCells
-
Prasad S, Yadav VR, Sung B, Reuter S, Kannappan R, Deorukhkar A, Diagaradjane P, Wei C, Baladandayuthapani V, Krishnan S, Guha S, Aggarwal BB. Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine. Clin Cancer Res. 2012 Sep 15; 18(18):4942-53.
PMID: 22832932; PMCID: PMC3677707.
Citations:
58 Fields:
Translation:
HumansAnimalsCells
-
Lu C, Stewart DJ, Lee JJ, Ji L, Ramesh R, Jayachandran G, Nunez MI, Wistuba II, Erasmus JJ, Hicks ME, Grimm EA, Reuben JM, Baladandayuthapani V, Templeton NS, McMannis JD, Roth JA. Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans. PLoS One. 2012; 7(4):e34833.
PMID: 22558101; PMCID: PMC3338819.
Citations:
58 Fields:
Translation:
HumansCTClinical Trials
-
Garrett CR, Hassabo HM, Bhadkamkar NA, Wen S, Baladandayuthapani V, Kee BK, Eng C, Hassan MM. Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer. Br J Cancer. 2012 Apr 10; 106(8):1374-8.
PMID: 22421948; PMCID: PMC3326682.
Citations:
68 Fields:
Translation:
Humans
-
Garrett CR, George B, Viswanathan C, Bhadkamkar NA, Wen S, Baladandayuthapani V, You YN, Kopetz ES, Overman MJ, Kee BK, Eng C. Survival benefit associated with surgical oophorectomy in patients with colorectal cancer metastatic to the ovary. Clin Colorectal Cancer. 2012 Sep; 11(3):191-4.
PMID: 22280844.
Citations:
7 Fields:
Translation:
Humans
-
Zheng Y, Yang J, Qian J, Zhang L, Lu Y, Li H, Lin H, Lan Y, Liu Z, He J, Hong S, Thomas S, Shah J, Baladandayuthapani V, Kwak LW, Yi Q. Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone. J Mol Med (Berl). 2012 Jun; 90(6):695-706.
PMID: 22207485; PMCID: PMC4212830.
Citations:
27 Fields:
Translation:
HumansAnimalsCells
-
Jones RJ, Baladandayuthapani V, Neelapu S, Fayad LE, Romaguera JE, Wang M, Sharma R, Yang D, Orlowski RZ. HDM-2 inhibition suppresses expression of ribonucleotide reductase subunit M2, and synergistically enhances gemcitabine-induced cytotoxicity in mantle cell lymphoma. Blood. 2011 Oct 13; 118(15):4140-9.
PMID: 21844567; PMCID: PMC3204731.
Citations:
23 Fields:
Translation:
HumansAnimalsCells
-
Thompson PA, Brewster AM, Kim-Anh D, Baladandayuthapani V, Broom BM, Edgerton ME, Hahn KM, Murray JL, Sahin A, Tsavachidis S, Wang Y, Zhang L, Hortobagyi GN, Mills GB, Bondy ML. Selective genomic copy number imbalances and probability of recurrence in early-stage breast cancer. PLoS One. 2011; 6(8):e23543.
PMID: 21858162; PMCID: PMC3155554.
Citations:
28 Fields:
Translation:
Humans
-
Morris JS, Baladandayuthapani V, Herrick RC, Sanna P, Gutstein H. AUTOMATED ANALYSIS OF QUANTITATIVE IMAGE DATA USING ISOMORPHIC FUNCTIONAL MIXED MODELS, WITH APPLICATION TO PROTEOMICS DATA. Ann Appl Stat. 2011 Jan 01; 5(2A):894-923.
PMID: 22408711; PMCID: PMC3298181.
-
Bonato V, Baladandayuthapani V, Broom BM, Sulman EP, Aldape KD, Do KA. Bayesian ensemble methods for survival prediction in gene expression data. Bioinformatics. 2011 Feb 01; 27(3):359-67.
PMID: 21148161; PMCID: PMC3031034.
Citations:
24 Fields:
Translation:
Humans
-
Baladandayuthapani V, Ji Y, Talluri R, Nieto-Barajas LE, Morris JS. Bayesian Random Segmentation Models to Identify Shared Copy Number Aberrations for Array CGH Data. J Am Stat Assoc. 2010 12; 105(492):1358-1375.
PMID: 21512611; PMCID: PMC3079218.
-
Lin YX, Baladandayuthapani V, Bonato V, Do KA. Estimating Shared Copy Number Aberrations for Array CGH Data: The Linear-Median Method. Cancer Inform. 2010 Oct 12; 9:229-49.
PMID: 21082039; PMCID: PMC2978932.
Citations:
-
Zhou L, Huang JZ, Martinez JG, Maity A, Baladandayuthapani V, Carroll RJ. Reduced Rank Mixed Effects Models for Spatially Correlated Hierarchical Functional Data. J Am Stat Assoc. 2010 03 01; 105(489):390-400.
PMID: 20396628; PMCID: PMC2853971.
-
Wang J, Xu J, Baladandayuthapani V. Contrast sensitivity of digital imaging display systems: contrast threshold dependency on object type and implications for monitor quality assurance and quality control in PACS. Med Phys. 2009 Aug; 36(8):3682-92.
PMID: 19746801; PMCID: PMC3910133.
Citations:
6 Fields:
Translation:
Humans
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Zhang N, Ge G, Meyer R, Sethi S, Basu D, Pradhan S, Zhao YJ, Li XN, Cai WW, El-Naggar AK, Baladandayuthapani V, Kittrell FS, Rao PH, Medina D, Pati D. Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):13033-8.
PMID: 18728194; PMCID: PMC2529090.
Citations:
69 Fields:
Translation:
HumansAnimalsCells
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Nehete PN, Nehete BP, Hill L, Manuri PR, Baladandayuthapani V, Feng L, Simmons J, Sastry KJ. Selective induction of cell-mediated immunity and protection of rhesus macaques from chronic SHIV(KU2) infection by prophylactic vaccination with a conserved HIV-1 envelope peptide-cocktail. Virology. 2008 Jan 05; 370(1):130-41.
PMID: 17920095; PMCID: PMC2196441.
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Aggarwal BB, Sethi G, Baladandayuthapani V, Krishnan S, Shishodia S. Targeting cell signaling pathways for drug discovery: an old lock needs a new key. J Cell Biochem. 2007 Oct 15; 102(3):580-92.
PMID: 17668425.
Citations:
51 Fields:
Translation:
HumansAnimalsCells
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Baladandayuthapani V, Mallick BK, Young Hong M, Lupton JR, Turner ND, Carroll RJ. Bayesian hierarchical spatially correlated functional data analysis with application to colon carcinogenesis. Biometrics. 2008 Mar; 64(1):64-73.
PMID: 17608780; PMCID: PMC2740995.
Citations:
38 Fields:
Translation:
Animals
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Phadke AP, de la Concha-Bermejillo A, Wolf AM, Andersen PR, Baladandayuthapani V, Collisson EW. Pathogenesis of a Texas feline immunodeficiency virus isolate: an emerging subtype of clade B. Vet Microbiol. 2006 Jun 15; 115(1-3):64-76.
PMID: 16574348.
Citations:
3 Fields:
Translation:
AnimalsCells
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Integrative Bayesian analysis of neuroimaging-genetic data with application to cocaine dependence. NeuroImage. 125:813-824.
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Latent feature decompositions for integrative analysis of multi-platform genomic data. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 11:984-994.
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A nonparametric bayesian technique for high-dimensional regression. Electronic Journal of Statistics. 10:3374-3424.
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Bayesian sparse graphical models for classification with application to protein expression data. Annals of Applied Statistics. 8:1443-1468.
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Spatially adaptive Bayesian penalized regression splines (P-splines). Journal of Computational and Graphical Statistics. 14:378-394.
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Mir-21-Sox2 axis delineates glioblastoma subtypes with prognostic impact. Journal of Neuroscience. 35:15097-15112.
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Reduced rank mixed effects models for spatially correlated hierarchical functional data. Journal of the American Statistical Association. 105:390-400.
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Regulates paclitaxel sensitivity in ovarian cancer cells by modulating AKT ativation, p21Cip1- and p27Kip1-mediated G1 cell cycle arrest and apoptosis. PLoS One. 10.
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Functional CAR Models for Large Spatially Correlated Functional Datasets. Journal of the American Statistical Association. 111:772-786.
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Outcome of Patients with Multiple Myeloma and CKS1B Gene Amplification after Autologous Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 22:2159-2164.
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Bayesian Analysis of Gene Expression Data.
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Nonparametric variable selection, clustering and prediction for large biological datasets. 175-192.
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Hierarchical Bayesian methods for integration of various types of genomics data. 5-8.
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Spatially adaptive Bayesian penalized regression splines (P-splines) (Journal of Computational and Graphical Statistics (2005) 14, 378-394). Journal of Computational and Graphical Statistics. 17:515.
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Lenalidomide, thalidomide, and pomalidomide reactivate the Epstein-Barr virus lytic cycle through phosphoinositide 3-kinase signaling and ikaros expression. Clinical Cancer Research. 22:4901-4912.
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Prognostic gene signature identification using causal structure learning. Cancer Informatics. 14:23-35.
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Bayesian sparse graphical models and their mixtures. Stat. 3:109-125.
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Latent feature decompositions for integrative analysis of diverse high-throughput genomic data. 130-134.
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Bayesian nonlinear model selection for gene regulatory networks. Biometrics. 71:585-595.
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Bayesian variable selection in linear regression in one pass for large datasets. ACM Transactions on Knowledge Discovery from Data. 9.
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PCAN. Biometrics.
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Bayesian hierarchical structured variable selection methods with application to molecular inversion probe studies in breast cancer. Journal of the Royal Statistical Society. Series C: Applied Statistics. 63:595-620.
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A fast convergence clustering algorithm merging MCMC and EM methods. 1525-1528.
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Data mining algorithms as a service in the cloud exploiting relational database systems. 1001-1004.
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Integrative analysis of multi-modal correlated imaging-genomics data in glioblastoma. 5-8.
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TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin. Scientific Reports. 6.
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DINGO. Bioinformatics. 31:3413-3420.
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Integrative sparse bayesian analysis of high-dimensional multi-platform genomic data in glioblastoma. 1-4.
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Exogenous restoration of TUSC2 expression induces responsiveness to erlotinib in wildtype epidermal growth factor receptor (EGFR) lung cancer cells through context specific pathways resulting in enhanced therapeutic efficacy. PLoS One. 10.
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Bayesian Methods for DNA Microarray Data Analysis. Handbook of Statistics. 25:713-742.
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Targeting the spleen tyrosine kinase with fostamatinib as a strategy against Waldenström Macroglobulinemia. Clinical Cancer Research. 21:2538-2545.
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Differentiation of low-attenuation intracranial hemorrhage and calcification using dual-energy computed tomography in a phantom system. Investigative Radiology.
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Integrative Bayesian analysis of neuroimaging-genetic data through hierarchical dimension reduction. 824-828.
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Bayesian variable selection for linear regression in high dimensional microarray data. 17-18.
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Bayesian disease classification using copy number data. Cancer Informatics. 13:83-91.
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Undertaking an art survey to compare patient versus student art preferences. Environment and Behavior. 40:269-301.
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Bayesian approaches for large biological networks. 153-174.
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Classification, Predictive modelling, And statistical analysis of cancer data (A). Cancer Informatics. 13:1-3.
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Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling. Cancer Cell.
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A Two-Sample Test for Equality of Means in High Dimension. Journal of the American Statistical Association. 110:837-849.
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A semiparametric Bayesian model for comparing DNA copy numbers. Brazilian Journal of Probability and Statistics. 30:345-365.
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Spatial modeling of annual minimum and maximum temperatures in Iceland. Meteorology and Atmospheric Physics. 116:43-61.
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Integrating multi-platform genomic data using hierarchical Bayesian relevance vector machines. 18-21.
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Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma. The Lancet Oncology. 15:69-77.
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Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer. British Journal of Cancer. 114:1352-1361.
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On the computation of stochastic search variable selection in linear regression with UDFs. 941-946.
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Selective Internal Radiation Therapy With Yttrium-90 Glass Microspheres. International Journal of Radiation Oncology Biology Physics. 96:888-896.
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Bayesian random segmentation models to identify shared copy number aberrations for array CGH data. Journal of the American Statistical Association. 105:1358-1375.
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Integrative Bayesian network analysis of genomic data. Cancer Informatics. 13:39-48.
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DEMARCATE. NeuroImage: Clinical. 12:132-143.
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Querying external source code files of programs connecting to a relational database. 9-16.
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Automated analysis of quantitative image data using isomorphic functional mixed models, with application to proteomics data. Annals of Applied Statistics. 5:894-923.
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Prediction-Oriented Marker Selection (PROMISE). Statistics in Biosciences. 1-29.
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Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Medicine. 14.