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ALEXANDER LAZAR

TitleProfessor
InstitutionMD Anderson
DepartmentPathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bowen MB, Melendez B, Zhang Q, Yang RK, Fellman BM, Lawson BC, Adjei NN, Celestino J, Wani KM, Singh B, Urbauer DL, Lazar AJ, Lu KH, Wargo JA, Westin SN, Yates MS, Bowen MB, Melendez B, Zhang Q, Yang RK, Fellman BM, Lawson BC, Adjei NN, Celestino J, Wani KM, Singh B, Urbauer DL, Lazar AJ, Lu KH, Wargo JA, Westin SN, Yates MS. Long-Term Follow-up of Levonorgestrel Intrauterine Device for Atypical Hyperplasia and Early Endometrial Cancer Reveals Relapse Characterized by Immune Exhaustion. Clin Cancer Res. 2024 Nov 15; 30(22):5073-5082. PMID: 38922360.
      Citations:    Fields:    
    2. Lucas CG, Gross AM, Romo CG, Dehner CA, Lazar AJ, Miettinen M, Pekmezci M, Quezado M, Rodriguez FJ, Stemmer-Rachamimov A, Viskochil D, Perry A, Symposium on Atypical Neurofibroma: State of the Science Members. Consensus recommendations for an integrated diagnostic approach to peripheral nerve sheath tumors arising in the setting of Neurofibromatosis type 1 (NF1). Neuro Oncol. 2024 Nov 06. PMID: 39500722.
      Citations:    
    3. Giani C, Salawu A, Ljevar S, Denu RA, Napolitano A, Palmerini E, Connolly EA, Ogura K, Wong DD, Scanferla R, Rosenbaum E, Bajpai J, Li ZC, Bae S, D'Ambrosio L, Bialick S, Wagner AJ, Lee ATJ, Kosela-Paterczyk H, Baldi GG, Brunello A, Lee YC, Loong HH, Boikos S, Campos F, Cicala CM, Maki RG, Hindi N, Figura C, Almohsen SS, Patel S, Jones RL, Ibrahim T, Karim R, Kawai A, Carey-Smith R, Boyle R, Taverna SM, Lazar AJ, Demicco EG, Bovee JVMG, Dei Tos AP, Fletcher C, Baumhoer D, Sbaraglia M, Schaefer IM, Miceli R, Gronchi A, Stacchiotti S. International Multicenter Retrospective Study From the Ultra-rare Sarcoma Working Group on Low-grade Fibromyxoid Sarcoma, Sclerosing Epithelioid Fibrosarcoma, and Hybrid Forms: Outcome of Primary Localized Disease. Am J Surg Pathol. 2024 Oct 28. PMID: 39466087.
      Citations:    Fields:    
    4. Beird HC, Cloutier JM, Gokgoz N, Eeles C, Griffin AM, Ingram DR, Wani KM, Segura RL, Cohen L, Ho C, Wunder JS, Andrulis IL, Futreal PA, Haibe-Kains B, Lazar AJ, Wang WL, Przybyl J, Demicco EG. Epigenomic and transcriptomic profiling of solitary fibrous tumors identifies site-specific patterns and candidate genes regulated by DNA methylation. Lab Invest. 2024 Sep 30; 102146. PMID: 39357799.
      Citations:    Fields:    
    5. Folkert IW, Molina Arocho WA, To TKJ, Devalaraja S, Molina IS, Shoush J, Mohei H, Zhai L, Akhtar MN, Kochat V, Arslan E, Lazar AJ, Wani K, Israel WP, Zhang Z, Chaluvadi VS, Norgard RJ, Liu Y, Fuller AM, Dang MT, Roses RE, Karakousis GC, Miura JT, Fraker DL, Eisinger-Mathason TSK, Simon MC, Weber K, Tan K, Fan Y, Rai K, Haldar M. An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis. J Exp Med. 2024 Oct 07; 221(10). PMID: 39347789; PMCID: PMC11457473.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Giani C, Denu RA, Ljevar S, Gronchi A, Napolitano A, Rosenbaum E, Salawu A, Bajpai J, Connolly EA, Lee ATJ, Trent JC, Kosela-Paterczyk H, Chia-Chen Li Z, Ogura K, Palmerini E, Baldi GG, Brunello A, Campos F, Cicala CM, Maki RG, Wagner AJ, Andelkovic V, Loong HH, Wong DD, Jones RL, Tap WD, Taverna SM, Lazar AJ, Demicco EG, Hong A, Bovee JVMG, Dei Tos AP, Fletcher CDM, Baumhoer D, Sbaraglia M, Schaefer IM, Miceli R, Stacchiotti S. Low-grade fibromyxoid sarcoma and sclerosing epithelioid fibrosarcoma, outcome of advanced disease: retrospective study from the Ultra-Rare Sarcoma Working Group. ESMO Open. 2024 Sep; 9(9):103689. PMID: 39265219; PMCID: PMC11416581.
      Citations:    Translation:Humans
    7. Sundaram L, Kumar A, Zatzman M, Salcedo A, Ravindra N, Shams S, Louie BH, Bagdatli ST, Myers MA, Sarmashghi S, Choi HY, Choi WY, Yost KE, Zhao Y, Granja JM, Hinoue T, Hayes DN, Cherniack A, Felau I, Choudhry H, Zenklusen JC, Farh KK, McPherson A, Curtis C, Laird PW, Cancer Genome Atlas Analysis Network?, Corces MR, Chang HY, Greenleaf WJ, Demchok JA, Yang L, Tarnuzzer R, Caesar-Johnson SJ, Wang Z, Doane AS, Khurana E, Castro MAA, Lazar AJ, Broom BM, Weinstein JN, Akbani R, Kumar SV, Raphael BJ, Wong CK, Stuart JM, Safavi R, Benz CC, Johnson BK, Kyi C, Shen H, Louie BH. Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers. Science. 2024 09 06; 385(6713):eadk9217. PMID: 39236169.
      Citations:    Fields:    Translation:HumansCells
    8. Lyu HG, Witt RG, Rajkot N, Keung EZ, Torres KE, Hunt KK, Somaiah N, Lazar AJ, Roland CL, Scally CP. Patterns of Care and Outcomes of Patients with Small Gastrointestinal Stromal Tumors at a High-Volume Sarcoma Center. Ann Surg Oncol. 2024 Dec; 31(13):9258-9264. PMID: 39230849.
      Citations:    Fields:    
    9. Patel RR, Delclos GL, DeSantis SM, Cannell MB, Lupo PJ, Bishop AJ, Lazar AJ, Lin PP, Benjamin RS, Patel SR, Ludwig J, Ravi V, Livingston JA, Somaiah N, Zarzour MA, Conley AP, Araujo DM. Does the Primary Tumor Site Drive Biology for Patients With Synovial Sarcoma? Am J Clin Oncol. 2024 Sep 03. PMID: 39224003.
      Citations:    Fields:    
    10. Huang J, Yuan C, Jiang J, Chen J, Badve SS, Gokmen-Polar Y, Segura RL, Yan X, Lazar A, Gao J, Epstein M, Wang L, Hu J. MorphLink: Bridging Cell Morphological Behaviors and Molecular Dynamics in Multi-modal Spatial Omics. bioRxiv. 2024 Aug 26. PMID: 39253421; PMCID: PMC11383057.
      Citations:    
    11. Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi MP, Lazcano R, Yamashita K, Xu Z, Pei G, Cho KS, Chu Y, Sinjab A, Peng F, Yan X, Han G, Wang R, Dai E, Dai Y, Czerniak BA, Futreal A, Maitra A, Lazar A, Kadara H, Jazaeri AA, Cheng X, Ajani J, Gao J, Hu J, Wang L. METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics. Nat Commun. 2024 Aug 25; 15(1):7312. PMID: 39181865; PMCID: PMC11344794.
      Citations:    Fields:    Translation:HumansCells
    12. Gingrich A, Wangsiricharoen S, Torres MB, Ravi V, Ratan R, Keung EZ, Scally CP, Lazar AJ, Wang WL, Roland CL, Hunt KK, Yu W, Torres KE. Clinical Variables Influencing Outcomes in Patients with Atypical Intradermal Smooth Muscle Neoplasms (Formerly Cutaneous Leiomyosarcomas): Single-Institution Study of 95 Surgical Patients. Ann Surg Oncol. 2024 Nov; 31(12):7950-7956. PMID: 39150618.
      Citations:    Fields:    Translation:Humans
    13. Nakazawa MS, Livingston JA, Zarzour MA, Bishop AJ, Ratan R, Ludwig JA, Araujo DM, Somaiah N, Ravi V, Nassif EF, Roland CL, Lazar AJ, Guadagnolo BA, Harrison DJ, Benjamin RS, Patel SR, Conley AP. Clinical characteristics and outcomes of adult alveolar rhabdomyosarcoma patients on first-line systemic therapies: A single-institution cohort. Rare Tumors. 2024; 16:20363613241271669. PMID: 39105190; PMCID: PMC11299201.
      Citations:    
    14. Kasper B, Baldini EH, Bonvalot S, Callegaro D, Cardona K, Colombo C, Corradini N, Crago AM, Dei Tos AP, Dileo P, Elnekave E, Erinjeri JP, Navid F, Farma JM, Ferrari A, Fiore M, Gladdy RA, Gounder M, Haas RL, Husson O, Kurtz JE, Lazar AJ, Orbach D, Penel N, Ratan R, Raut CP, Roland CL, Schut AW, Sparber-Sauer M, Strauss DC, Van der Graaf WTA, Vitellaro M, Weiss AR, Gronchi A, Desmoid Tumor Working Group. Current Management of Desmoid Tumors: A Review. JAMA Oncol. 2024 Aug 01; 10(8):1121-1128. PMID: 38900421.
      Citations: 2     Fields:    Translation:Humans
    15. Lazcano R, Ingram DR, Panse G, Lazar AJ, Wang WL, Cloutier JM, Panse G. TRPS1 expression in MPNST is correlated with PRC2 inactivation and loss of H3K27me3. Hum Pathol. 2024 09; 151:105632. PMID: 39084565.
      Citations:    Fields:    Translation:Humans
    16. Nakazawa MS, Silverman IM, Rimkunas V, Veloso A, Glodzik D, Johnson A, Ohsumi TK, Patel SR, Conley AP, Roland CL, Soliman PT, Beird HC, Wu CC, Ingram DR, Lazcano R, Song D, Wani KM, Lazar AJ, Yap TA, Wang WL, Livingston JA, Nakazawa MS, Silverman IM, Rimkunas V, Veloso A, Glodzik D, Johnson A, Ohsumi TK, Patel SR, Conley AP, Roland CL, Soliman PT, Beird HC, Wu CC, Ingram DR, Lazcano R, Song D, Wani KM, Lazar AJ, Yap TA, Wang WL, Livingston JA. Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Mol Cancer Ther. 2024 Jul 02; 23(7):1057-1065. PMID: 38561019; PMCID: PMC11321279.
      Citations: 1     Fields:    Translation:HumansCells
    17. Hirbe AC, Dehner CA, Dombi E, Eulo V, Gross AM, Sundby T, Lazar AJ, Widemann BC. Contemporary Approach to Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors. Am Soc Clin Oncol Educ Book. 2024 Jun; 44(3):e432242. PMID: 38710002.
      Citations: 1     Fields:    Translation:Humans
    18. Raso MG, Barrientos Toro E, Evans K, Rizvi Y, Lazcano R, Akcakanat A, Sini P, Trapani F, Madlener EJ, Waldmeier L, Lazar A, Meric-Bernstam F. Heterogeneous Profile of ROR1 Protein Expression across Tumor Types. Cancers (Basel). 2024 May 15; 16(10). PMID: 38791952; PMCID: PMC11119314.
      Citations: 1     
    19. Pilie PG, Giuliani V, Wang WL, McGrail DJ, Bristow CA, Ngoi NYL, Kyewalabye K, Wani KM, Le H, Campbell E, S?nchez NS, Yang D, Gheeya JS, Goswamy RV, Holla V, Shaw KR, Meric-Bernstam F, Liu CY, Ma X, Feng N, Machado AA, Bardenhagen JP, Vellano CP, Marszalek JR, Rajendra E, Piscitello D, Johnson TI, Likhatcheva M, Elinati E, Majithiya J, Neves J, Grinkevich V, Ranzani M, Roy-Luzarraga M, Boursier M, Armstrong L, Geo L, Lillo G, Tse WY, Lazar AJ, Kopetz SE, Geck Do MK, Lively S, Johnson MG, Robinson HMR, Smith GCM, Carroll CL, Di Francesco ME, Jones P, Heffernan TP, Yap TA, Pili? PG, Giuliani V, Wang WL, McGrail DJ, Bristow CA, Ngoi NYL, Kyewalabye K, Wani KM, Le H, Campbell E, Sanchez NS, Yang D, Gheeya JS, Goswamy RV, Holla V, Shaw KR, Meric-Bernstam F, Liu CY, Ma X, Feng N, Machado AA, Bardenhagen JP, Vellano CP, Marszalek JR, Rajendra E, Piscitello D, Johnson TI, Likhatcheva M, Elinati E, Majithiya J, Neves J, Grinkevich V, Ranzani M, Luzarraga MR, Boursier M, Armstrong L, Geo L, Lillo G, Tse WY, Lazar AJ, Kopetz SE, Geck Do MK, Lively S, Johnson MG, Robinson HMR, Smith GCM, Carroll CL, Di Francesco ME, Jones P, Heffernan TP, Yap TA. Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clin Cancer Res. 2024 May 15; 30(10):2121-2139. PMID: 38416404; PMCID: PMC11094420.
      Citations:    Fields:    Translation:HumansAnimalsCells
    20. Nasr LF, Zoghbi M, Lazcano R, Nakazawa M, Bishop AJ, Farooqi A, Mitra D, Guadagnolo BA, Benjamin R, Patel S, Ravi V, Araujo DM, Livingston A, Zarzour MA, Conley AP, Ratan R, Somaiah N, Lazar AJ, Roland C, Keung EZ, Nassif Haddad EF. High-Grade Pleomorphic Sarcomas Treated with Immune Checkpoint Blockade: The MD Anderson Cancer Center Experience. Cancers (Basel). 2024 May 01; 16(9). PMID: 38730715; PMCID: PMC11083765.
      Citations:    
    21. Denu RA, Joseph CP, Urquiola ES, Byrd PS, Yang RK, Ratan R, Zarzour MA, Conley AP, Araujo DM, Ravi V, Nassif Haddad EF, Nakazawa MS, Patel S, Wang WL, Lazar AJ, Somaiah N. Utility of Clinical Next Generation Sequencing Tests in KIT/PDGFRA/SDH Wild-Type Gastrointestinal Stromal Tumors. Cancers (Basel). 2024 Apr 27; 16(9). PMID: 38730662; PMCID: PMC11083047.
      Citations: 1     
    22. Chen A, Sharma N, Patel P, Olivares S, Bahrami A, Barnhill RL, Blokx WAM, Bosenberg M, Busam KJ, de La Fouchardi?re A, Duncan LM, Elder DE, Ko JS, Landman G, Lazar AJ, Lezcano C, Lowe L, Maher N, Massi D, Messina J, Mihic-Probst D, Parker DC, Redpath M, Scolyer RA, Shea CR, Spatz A, Tron V, Xu X, Yeh I, Jung Yun S, Zembowicz A, Gerami P. The Impact of Next-generation Sequencing on Interobserver Agreement and Diagnostic Accuracy of Desmoplastic Melanocytic Neoplasms. Am J Surg Pathol. 2024 Jun 01; 48(6):708-718. PMID: 38590014.
      Citations:    Fields:    Translation:Humans
    23. Gerami P, Chen A, Sharma N, Patel P, Hagstrom M, Kancherla P, Geraminejad T, Olivares S, Biswas A, Bosenberg M, Busam KJ, de La Fouchardi?re A, Duncan LM, Elder DE, Ko J, Landman G, Lazar AJ, Lowe L, Massi D, Mihic-Probst D, Parker DC, Scolyer RA, Shea CR, Zembowicz A, Yun SJ, Blokx WAM, Barnhill RL. BRAF Mutated and Morphologically Spitzoid Tumors, a Subgroup of Melanocytic Neoplasms Difficult to Distinguish From True Spitz Neoplasms. Am J Surg Pathol. 2024 May 01; 48(5):538-545. PMID: 38525831.
      Citations:    Fields:    Translation:Humans
    24. Beird HC, Lin D, Lazar AJ, Futreal PA. Patterns of structural variants within TP53 introns and relocation of the TP53 promoter: a commentary?. J Pathol. 2024 06; 263(2):131-134. PMID: 38482738.
      Citations:    Fields:    Translation:HumansCells
    25. Xie X, Ghadimi MPH, Young ED, Belousov R, Zhu QS, Liu J, Lopez G, Colombo C, Peng T, Reynoso D, Hornick JL, Lazar AJ, Lev D. Editor's Note: Combining EGFR and mTOR Blockade for the Treatment of Epithelioid Sarcoma. Clin Cancer Res. 2024 Feb 16; 30(4):921. PMID: 38362726.
      Citations:    Fields:    
    26. Petralia F, Ma W, Yaron TM, Caruso FP, Tignor N, Wang JM, Charytonowicz D, Johnson JL, Huntsman EM, Marino GB, Calinawan A, Evangelista JE, Selvan ME, Chowdhury S, Rykunov D, Krek A, Song X, Turhan B, Christianson KE, Lewis DA, Deng EZ, Clarke DJB, Whiteaker JR, Kennedy JJ, Zhao L, Segura RL, Batra H, Raso MG, Parra ER, Soundararajan R, Tang X, Li Y, Yi X, Satpathy S, Wang Y, Wiznerowicz M, Gonz?lez-Robles TJ, Iavarone A, Gosline SJC, Reva B, Robles AI, Nesvizhskii AI, Mani DR, Gillette MA, Klein RJ, Cieslik M, Zhang B, Paulovich AG, Sebra R, G?m?s ZH, Hostetter G, Feny? D, Omenn GS, Cantley LC, Ma'ayan A, Lazar AJ, Ceccarelli M, Wang P, Clinical Proteomic Tumor Analysis Consortium. Pan-cancer proteogenomics characterization of tumor immunity. Cell. 2024 Feb 29; 187(5):1255-1277.e27. PMID: 38359819; PMCID: PMC10988632.
      Citations: 6     Fields:    Translation:Humans
    27. Roland CL, Nassif Haddad EF, Keung EZ, Wang WL, Lazar AJ, Lin H, Chelvanambi M, Parra ER, Wani K, Guadagnolo BA, Bishop AJ, Burton EM, Hunt KK, Torres KE, Feig BW, Scally CP, Lewis VO, Bird JE, Ratan R, Araujo D, Zarzour MA, Patel S, Benjamin R, Conley AP, Livingston JA, Ravi V, Tawbi HA, Lin PP, Moon BS, Satcher RL, Mujtaba B, Witt RG, Traweek RS, Cope B, Lazcano R, Wu CC, Zhou X, Mohammad MM, Chu RA, Zhang J, Damania A, Sahasrabhojane P, Tate T, Callahan K, Nguyen S, Ingram D, Morey R, Crosby S, Mathew G, Duncan S, Lima CF, Blay JY, Fridman WH, Shaw K, Wistuba I, Futreal A, Ajami N, Wargo JA, Somaiah N. A randomized, non-comparative phase 2 study of neoadjuvant immune-checkpoint blockade in retroperitoneal dedifferentiated liposarcoma and extremity/truncal undifferentiated pleomorphic sarcoma. Nat Cancer. 2024 Apr; 5(4):625-641. PMID: 38351182.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    28. Pozner A, Li L, Verma SP, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, John CM, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Mortenson KL, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97. Nat Commun. 2024 Feb 07; 15(1):1165. PMID: 38326311; PMCID: PMC10850509.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    29. Dehner CA, Chrisinger JSA, Lazar AJ. Updates on WHO classification for small round cell tumors: Ewing sarcoma vs. everything else. Hum Pathol. 2024 05; 147:101-113. PMID: 38280658.
      Citations: 3     Fields:    Translation:Humans
    30. Wangsiricharoen S, Ingram DR, Morey RR, Wani K, Lazar AJ, Wang WL. Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Immunohistochemistry Can Be a Useful Ancillary Tool to Identify Perivascular Epithelioid Cell Tumor. Mod Pathol. 2024 Mar; 37(3):100426. PMID: 38219952.
      Citations:    Fields:    Translation:Humans
    31. Hu J, Lazar AJ, Ingram D, Wang WL, Zhang W, Jia Z, Ragoonanan D, Wang J, Xia X, Mahadeo K, Gorlick R, Li S. Cell membrane-anchored and tumor-targeted IL-12 T-cell therapy destroys cancer-associated fibroblasts and disrupts extracellular matrix in heterogenous osteosarcoma xenograft models. J Immunother Cancer. 2024 01 09; 12(1). PMID: 38199607; PMCID: PMC10806671.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    32. Ozenberger BB, Li L, Wilson ER, Lazar AJ, Barrott JJ, Jones KB. EWSR1::ATF1 Orchestrates the Clear Cell Sarcoma Transcriptome in Human Tumors and a Mouse Genetic Model. Cancers (Basel). 2023 Dec 08; 15(24). PMID: 38136296; PMCID: PMC10742207.
      Citations: 2     
    33. Denu RA, Yang RK, Lazar AJ, Patel SS, Lewis VO, Roszik J, Livingston JA, Wang WL, Shaw KR, Ratan R, Zarzour MA, Bird J, Raza S, Akdemir KC, Rodon Ahnert J, Subbiah V, Patel S, Conley AP. Clinico-Genomic Profiling of Conventional and Dedifferentiated Chondrosarcomas Reveals TP53 Mutation to Be Associated with Worse Outcomes. Clin Cancer Res. 2023 12 01; 29(23):4844-4852. PMID: 37747813; PMCID: PMC10835757.
      Citations:    Fields:    Translation:Humans
    34. Wangsiricharoen S, Lazar AJ, Wang WL, Kerr DA, Margolis M, Mata DA, Rodrigues Simoes NJ, Faquin WC, Dias-Santagata D, Chopra S, Charville GW, Rosenberg AE, Tse JY, Cloutier JM. GLI1-Altered Mesenchymal Tumors With ACTB or PTCH1 Fusion: A Molecular and Clinicopathologic Analysis. Mod Pathol. 2024 Feb; 37(2):100386. PMID: 37992966.
      Citations:    Fields:    Translation:Humans
    35. Denu RA, Moyers JT, Gouda MA, Conley AP, Lazar AJ, Subbiah V. The Landscape of Alterations from 1407 Ultra-Rare Sarcomas from the AACR GENIE Database: Clinical Implications. Clin Cancer Res. 2023 11 14; 29(22):4669-4678. PMID: 37643131.
      Citations: 1     Fields:    Translation:Humans
    36. Deng N, Reyes-Uribe L, Fahrmann JF, Thoman WS, Munsell MF, Dennison JB, Murage E, Wu R, Hawk ET, Thirumurthi S, Lynch PM, Dieli-Conwright CM, Lazar AJ, Jindal S, Chu K, Chelvanambi M, Basen-Engquist K, Li Y, Wargo JA, McAllister F, Allison JP, Sharma P, Sinha KM, Hanash S, Gilchrist SC, Vilar E. Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-Associated Immunity in Lynch Syndrome. Clin Cancer Res. 2023 11 01; 29(21):4361-4372. PMID: 37724990; PMCID: PMC10618653.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    37. Pozner A, Verma SP, Li L, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, Mortenson KL, John C, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97. bioRxiv. 2023 Oct 02. PMID: 37873234; PMCID: PMC10592841.
      Citations:    
    38. Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, de Oliveira Araujo IB, Berti E, Bhagat G, Borges AM, Boyer D, Calaminici M, Chadburn A, Chan JKC, Cheuk W, Chng WJ, Choi JK, Chuang SS, Coupland SE, Czader M, Dave SS, de Jong D, Di Napoli A, Du MQ, Elenitoba-Johnson KS, Ferry J, Geyer J, Gratzinger D, Guitart J, Gujral S, Harris M, Harrison CJ, Hartmann S, Hochhaus A, Jansen PM, Karube K, Kempf W, Khoury J, Kimura H, Klapper W, Kovach AE, Kumar S, Lazar AJ, Lazzi S, Leoncini L, Leung N, Leventaki V, Li XQ, Lim MS, Liu WP, Louissaint A, Marcogliese A, Medeiros LJ, Michal M, Miranda RN, Mitteldorf C, Montes-Moreno S, Morice W, Nardi V, Naresh KN, Natkunam Y, Ng SB, Oschlies I, Ott G, Parrens M, Pulitzer M, Rajkumar SV, Rawstron AC, Rech K, Rosenwald A, Said J, Sarkozy C, Sayed S, Saygin C, Schuh A, Sewell W, Siebert R, Sohani AR, Suzuki R, Tooze R, Traverse-Glehen A, Vega F, Vergier B, Wechalekar AD, Wood B, Xerri L, Xiao W, International Agency for Research on Cancer/World Health Organization. Correction: "The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms" Leukemia. 2022 Jul;36(7):1720-1748. Leukemia. 2023 Sep; 37(9):1944-1951. PMID: 37468552; PMCID: PMC10457187.
      Citations:    Fields:    
    39. Li Y, Porta-Pardo E, Tokheim C, Bailey MH, Yaron TM, Stathias V, Geffen Y, Imbach KJ, Cao S, Anand S, Akiyama Y, Liu W, Wyczalkowski MA, Song Y, Storrs EP, Wendl MC, Zhang W, Sibai M, Ruiz-Serra V, Liang WW, Terekhanova NV, Rodrigues FM, Clauser KR, Heiman DI, Zhang Q, Aguet F, Calinawan AP, Dhanasekaran SM, Birger C, Satpathy S, Zhou DC, Wang LB, Baral J, Johnson JL, Huntsman EM, Pugliese P, Colaprico A, Iavarone A, Chheda MG, Ricketts CJ, Feny? D, Payne SH, Rodriguez H, Robles AI, Gillette MA, Kumar-Sinha C, Lazar AJ, Cantley LC, Getz G, Ding L, Clinical Proteomic Tumor Analysis Consortium. Pan-cancer proteogenomics connects oncogenic drivers to functional states. Cell. 2023 08 31; 186(18):3921-3944.e25. PMID: 37582357.
      Citations: 5     Fields:    Translation:Humans
    40. Geffen Y, Anand S, Akiyama Y, Yaron TM, Song Y, Johnson JL, Govindan A, Babur ?, Li Y, Huntsman E, Wang LB, Birger C, Heiman DI, Zhang Q, Miller M, Maruvka YE, Haradhvala NJ, Calinawan A, Belkin S, Kerelsky A, Clauser KR, Krug K, Satpathy S, Payne SH, Mani DR, Gillette MA, Dhanasekaran SM, Thiagarajan M, Mesri M, Rodriguez H, Robles AI, Carr SA, Lazar AJ, Aguet F, Cantley LC, Ding L, Getz G, Clinical Proteomic Tumor Analysis Consortium. Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation. Cell. 2023 08 31; 186(18):3945-3967.e26. PMID: 37582358; PMCID: PMC10680287.
      Citations: 4     Fields:    Translation:HumansCells
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    45. Beird HC, Wu CC, Nakazawa M, Ingram D, Daniele JR, Lazcano R, Little L, Davies C, Daw NC, Wani K, Wang WL, Song X, Gumbs C, Zhang J, Rubin B, Conley A, Flanagan AM, Lazar AJ, Futreal PA. Complete loss of TP53 and RB1 is associated with complex genome and low immune infiltrate in pleomorphic rhabdomyosarcoma. HGG Adv. 2023 10 12; 4(4):100224. PMID: 37593416; PMCID: PMC10428123.
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    81. Barnhill R, van Laere S, Vermeulen P, Roman-Roman S, Gardrat S, Alsafadi S, Tarin M, Champenois G, Servois V, Rodrigues M, Scolyer R, Lazar A, Romano E, Piperno-Neumann S, Mariani P, Lugassy C, Nicolas A, Matet A, Cassoux N. L1CAM and laminin vascular network: Association with the high-risk replacement histopathologic growth pattern in uveal melanoma liver metastases. Lab Invest. 2022 11; 102(11):1214-1224. PMID: 35672380.
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    82. Lamhamedi-Cherradi SE, Maitituoheti M, Menegaz BA, Krishnan S, Vetter AM, Camacho P, Wu CC, Beird HC, Porter RW, Ingram DR, Ramamoorthy V, Mohiuddin S, McCall D, Truong DD, Cuglievan B, Futreal PA, Velasco AR, Anvar NE, Utama B, Titus M, Lazar AJ, Wang WL, Rodriguez-Aguayo C, Ratan R, Livingston JA, Rai K, MacLeod AR, Daw NC, Hayes-Jordan A, Ludwig JA. The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma. Nat Commun. 2022 06 01; 13(1):3057. PMID: 35650195; PMCID: PMC9160255.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    83. Wang Y, Tian X, Zhang W, Zhang Z, Lazcano R, Hingorani P, Roth ME, Gill JD, Harrison DJ, Xu Z, Jusu S, Kannan S, Wang J, Lazar AJ, Earley EJ, Erickson SW, Gelb T, Huxley P, Lahdenranta J, Mudd G, Kurmasheva RT, Houghton PJ, Smith MA, Kolb EA, Gorlick R. Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma. Mol Cancer Ther. 2022 06 01; 21(6):903-913. PMID: 35312779; PMCID: PMC9167717.
      Citations:    Fields:    Translation:HumansCells
    84. Hailemichael Y, Johnson DH, Abdel-Wahab N, Foo WC, Bentebibel SE, Daher M, Haymaker C, Wani K, Saberian C, Ogata D, Kim ST, Nurieva R, Lazar AJ, Abu-Sbeih H, Fa'ak F, Mathew A, Wang Y, Falohun A, Trinh V, Zobniw C, Spillson C, Burks JK, Awiwi M, Elsayes K, Soto LS, Melendez BD, Davies MA, Wargo J, Curry J, Yee C, Lizee G, Singh S, Sharma P, Allison JP, Hwu P, Ekmekcioglu S, Diab A. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 2022 05 09; 40(5):509-523.e6. PMID: 35537412; PMCID: PMC9221568.
      Citations:    Fields:    Translation:HumansAnimalsCells
    85. Zullow HJ, Sankar A, Ingram DR, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J, Lazar AJ, Kadoch C, Sam? Guerra DD. The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma. Mol Cell. 2022 05 05; 82(9):1737-1750.e8. PMID: 35390276; PMCID: PMC9465545.
      Citations: 1     Fields:    Translation:AnimalsCells
    86. Wu CC, Beird HC, Lamhamedi-Cherradi SE, Soeung M, Ingram D, Truong DD, Porter RW, Krishnan S, Little L, Gumbs C, Zhang J, Titus M, Genovese G, Ludwig JA, Lazar AJ, Hayes-Jordan A, Futreal PA. Multi-site desmoplastic small round cell tumors are genetically related and immune-cold. NPJ Precis Oncol. 2022 Apr 04; 6(1):21. PMID: 35379887; PMCID: PMC8980094.
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    87. Lazar AJ, Nos? V. Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Familial Tumor Syndromes. Head Neck Pathol. 2022 Mar; 16(1):143-157. PMID: 35312981; PMCID: PMC9018953.
      Citations: 1     Fields:    Translation:Humans
    88. Molina ER, Chim LK, Lamhamedi-Cherradi SE, Mohiuddin S, McCall D, Cuglievan B, Krishnan S, Porter RW, Ingram DR, Wang WL, Lazar AJ, Scott DW, Truong DD, Daw NC, Ludwig JA, Mikos AG. Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients. Oncotarget. 2022; 13:521-533. PMID: 35284040; PMCID: PMC8906536.
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    89. Bhalla AD, Landers SM, Singh AK, Landry JP, Yeagley MG, Myerson GSB, Delgado-Baez CB, Dunnand S, Nguyen T, Ma X, Bolshakov S, Menegaz BA, Lamhamedi-Cherradi SE, Mao X, Song X, Lazar AJ, McCutcheon IE, Slopis JM, Ludwig JA, Lev DC, Rai K, Torres KE. Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor. Lab Invest. 2022 06; 102(6):658-666. PMID: 35228656.
      Citations:    Fields:    Translation:HumansAnimals
    90. Nozzoli F, Lazar AJ, Castiglione F, Campanacci DA, Beltrami G, De Logu F, Caporalini C, Massi D, Roviello G. NTRK Fusions Detection in Paediatric Sarcomas to Expand the Morphological Spectrum and Clinical Relevance of Selected Entities. Pathol Oncol Res. 2022; 28:1610237. PMID: 35295613; PMCID: PMC8919346.
      Citations: 1     Fields:    Translation:Humans
    91. Indave Ruiz BI, Armon S, Watanabe R, Uttley L, White VA, Lazar AJ, Cree IA. Clonality, Mutation and Kaposi Sarcoma: A Systematic Review. Cancers (Basel). 2022 Feb 25; 14(5). PMID: 35267506; PMCID: PMC8909603.
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    92. Nassif EF, Cope B, Traweek R, Witt RG, Erstad DJ, Scally CP, Thirasastr P, Zarzour MA, Ludwig J, Benjamin R, Bishop AJ, Guadagnolo BA, Ingram D, Wani K, Wang WL, Lazar AJ, Torres KE, Hunt KK, Feig BW, Roland CL, Somaiah N, Keung EZ. Real-world use of palbociclib monotherapy in retroperitoneal liposarcomas at a large volume sarcoma center. Int J Cancer. 2022 06 15; 150(12):2012-2024. PMID: 35128664.
      Citations:    Fields:    Translation:Humans
    93. Wang J, Wang WL, Sun H, Huo L, Wu Y, Chen H, Gan Q, Meis JM, Maloney N, Lazar AJ, Yoon EC, Albarracin CT, Krishnamurthy S, Middleton LP, Resetkova E, Yu W, Tan D, Lu W, Solis Soto LM, Wang S, Wistuba II, Parwani AV, Prieto VG, Sahin AA, Li Z, Ding Q. Expression of TRPS1 in phyllodes tumor and sarcoma of the breast. Hum Pathol. 2022 03; 121:73-80. PMID: 35063444.
      Citations:    Fields:    Translation:Humans
    94. Bill KLJ, Garnett J, Meaux I, Ma X, Creighton CJ, Bolshakov S, Barriere C, Debussche L, Lazar AJ, Prudner BC, Casadei L, Braggio D, Lopez G, Zewdu A, Bid H, Dina L, Pollock RE. Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma. Clin Cancer Res. 2022 Jan 15; 28(2):431. PMID: 35045964.
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    95. Spencer CN, McQuade JL, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X, White MG, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, Andrews MC, Rodrigues RR, Morgun A, Kim YS, Roszik J, Hoffman KL, Zheng J, Zhou Y, Medik YB, Kahn LM, Johnson S, Hudgens CW, Wani K, Gaudreau PO, Harris AL, Jamal MA, Baruch EN, Perez-Guijarro E, Day CP, Merlino G, Pazdrak B, Lochmann BS, Szczepaniak-Sloane RA, Arora R, Anderson J, Zobniw CM, Posada E, Sirmans E, Simon J, Haydu LE, Burton EM, Wang L, Dang M, Clise-Dwyer K, Schneider S, Chapman T, Anang NAS, Duncan S, Toker J, Malke JC, Glitza IC, Amaria RN, Tawbi HA, Diab A, Wong MK, Patel SP, Woodman SE, Davies MA, Ross MI, Gershenwald JE, Lee JE, Hwu P, Jensen V, Samuels Y, Straussman R, Ajami NJ, Nelson KC, Nezi L, Petrosino JF, Futreal PA, Lazar AJ, Hu J, Jenq RR, Tetzlaff MT, Yan Y, Garrett WS, Huttenhower C, Sharma P, Watowich SS, Allison JP, Cohen L, Trinchieri G, Daniel CR, Wargo JA. Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response. Science. 2021 Dec 24; 374(6575):1632-1640. PMID: 34941392; PMCID: PMC8970537.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    96. Pfister SM, Chan JKC, Hasle H, Lazar AJ, Ferrari A, Jarzembowski JA, Pritchard-Jones K, Hill DA, Jacques TS, von Deimling A, Kratz CP, Cree IA, Reyes-M?gica M, Rossi S, Wesseling P, L?pez Terrada DH, Alaggio R. A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era. Cancer Discov. 2022 02; 12(2):331-355. PMID: 34921008; PMCID: PMC9401511.
      Citations: 2     Fields:    Translation:Humans
    97. Benton S, Zhao J, Zhang B, Bahrami A, Barnhill RL, Busam K, Cerroni L, Cook MG, Elder DE, Johansson I, Lazar A, LeBoit P, Lowe L, Massi D, Duncan LM, Messina J, Mihic-Probst D, Mihm MC, Piepkorn MW, Schmidt B, Scolyer RA, Shea CR, Tetzlaff MT, Tron VA, Xu X, Yeh I, Yun SJ, Zembowicz A, Gerami P, de la Fouchardi?re A, Landman G. Impact of Next-generation Sequencing on Interobserver Agreement and Diagnosis of Spitzoid Neoplasms. Am J Surg Pathol. 2021 12 01; 45(12):1597-1605. PMID: 34757982.
      Citations: 2     Fields:    Translation:Humans
    98. White MG, Szczepaniak Sloane R, Witt RG, Reuben A, Gaudreau PO, Andrews MC, Feng N, Johnson S, Class CA, Bristow C, Wani K, Hudgens C, Nezi L, Manzo T, De Macedo MP, Hu J, Davis R, Jiang H, Prieto P, Burton E, Hwu P, Tawbi H, Gershenwald J, Lazar AJ, Tetzlaff MT, Overwijk W, Woodman SE, Cooper ZA, Marszalek JR, Davies MA, Heffernan TP, Wargo JA. Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma. Oncoimmunology. 2021; 10(1):1992880. PMID: 34777916; PMCID: PMC8583008.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    99. Ramani NS, Patel KP, Routbort MJ, Alvarez H, Broaddus R, Chen H, Rashid A, Lazar A, Lucas FAS, Yao H, Manekia J, Dang H, Barkoh BA, Medeiros LJ, Luthra R, Roy-Chowdhuri S. Factors Impacting Clinically Relevant RNA Fusion Assays Using Next-Generation Sequencing. Arch Pathol Lab Med. 2021 11 01; 145(11):1405-1412. PMID: 33493304.
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    100. Sloane RAS, White MG, Witt RG, Banerjee A, Davies MA, Han G, Burton E, Ajami N, Simon JM, Bernatchez C, Haydu LE, Tawbi HA, Gershenwald JE, Keung E, Ross M, McQuade J, Amaria RN, Wani K, Lazar AJ, Woodman SE, Wang L, Andrews MC, Wargo JA. Identification of MicroRNA-mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes. Cancers (Basel). 2021 Oct 22; 13(21). PMID: 34771465; PMCID: PMC8582574.
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    101. Marx A, Chan JKC, Chalabreysse L, Dacic S, Detterbeck F, French CA, Hornick JL, Inagaki H, Jain D, Lazar AJ, Marino M, Marom EM, Moreira AL, Nicholson AG, Noguchi M, Nonaka D, Papotti MG, Porubsky S, Sholl LM, Tateyama H, Travis WD, Rajan A, Roden AC, Thomas de Montpr?ville V, Str?bel P. The 2021 WHO Classification of Tumors of the Thymus and Mediastinum: What Is New in Thymic Epithelial, Germ Cell, and Mesenchymal Tumors? J Thorac Oncol. 2022 02; 17(2):200-213. PMID: 34695605.
      Citations: 6     Fields:    Translation:HumansCells
    102. AUC Committee Members, Fung MA, Vidal CI, Armbrecht EA, Andea AA, Cassarino DS, Comfere NI, Emanuel PO, Ferringer T, Hristov AC, Kim J, Lauer SR, Linos K, Missall TA, Motaparthi K, Novoa RA, Patel R, Shalin SC, Sundram U, Rating Panel, Calame A, Bennett DD, Duncan LM, Elston DM, Hosler GA, Hurley YM, Lazar AJ, Lowe L, Messina J, Myles J, Plaza JA, Prieto VG, Reddy V, Subtil A, Schaffer A. Appropriate use criteria for ancillary diagnostic testing in dermatopathology: New recommendations for 11 tests and 220 clinical scenarios from the American Society of Dermatopathology Appropriate Use Criteria Committee. J Cutan Pathol. 2022 Mar; 49(3):231-245. PMID: 34536035.
      Citations:    Fields:    Translation:Humans
    103. Vega DM, Yee LM, McShane LM, Williams PM, Chen L, Vilimas T, Fabrizio D, Funari V, Newberg J, Bruce LK, Chen SJ, Baden J, Carl Barrett J, Beer P, Butler M, Cheng JH, Conroy J, Cyanam D, Eyring K, Garcia E, Green G, Gregersen VR, Hellmann MD, Keefer LA, Lasiter L, Lazar AJ, Li MC, MacConaill LE, Meier K, Mellert H, Pabla S, Pallavajjalla A, Pestano G, Salgado R, Samara R, Sokol ES, Stafford P, Budczies J, Stenzinger A, Tom W, Valkenburg KC, Wang XZ, Weigman V, Xie M, Xie Q, Zehir A, Zhao C, Zhao Y, Stewart MD, Allen J, TMB Consortium. Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project. Ann Oncol. 2021 12; 32(12):1626-1636. PMID: 34606929.
      Citations: 10     Fields:    Translation:Humans
    104. Panza E, Ozenberger BB, Straessler KM, Barrott JJ, Li L, Wang Y, Xie M, Boulet A, Titen SW, Mason CC, Lazar AJ, Ding L, Capecchi MR, Jones KB. The clear cell sarcoma functional genomic landscape. J Clin Invest. 2021 08 02; 131(15). PMID: 34156976; PMCID: PMC8321568.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    105. Kochat V, Raman AT, Landers SM, Tang M, Schulz J, Terranova C, Landry JP, Bhalla AD, Beird HC, Wu CC, Jiang Y, Mao X, Lazcano R, Gite S, Ingram DR, Yi M, Zhang J, Keung EZ, Scally CP, Roland CL, Hunt KK, Feig BW, Futreal PA, Hwu P, Wang WL, Lazar AJ, Slopis JM, Wilson-Robles H, Wiener DJ, McCutcheon IE, Wustefeld-Janssens B, Rai K, Torres KE. Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state. Acta Neuropathol. 2021 09; 142(3):565-590. PMID: 34283254.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    106. Terranova CJ, Tang M, Maitituoheti M, Raman AT, Ghosh AK, Schulz J, Amin SB, Orouji E, Tomczak K, Sarkar S, Oba J, Creasy C, Wu CJ, Khan S, Lazcano R, Wani K, Singh A, Barrodia P, Zhao D, Chen K, Haydu LE, Wang WL, Lazar AJ, Woodman SE, Bernatchez C, Rai K. Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy. Cell Rep. 2021 07 20; 36(3):109410. PMID: 34289358; PMCID: PMC8369408.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    107. Andrews MC, Duong CPM, Gopalakrishnan V, Iebba V, Chen WS, Derosa L, Khan MAW, Cogdill AP, White MG, Wong MC, Ferrere G, Roberti MP, Opolon P, Alou MT, Yonekura S, Roh W, Spencer CN, Curbelo IF, Vence L, Reuben A, Johnson S, Arora R, Morad G, Lastrapes M, Baruch EN, Little L, Gumbs C, Cooper ZA, Prieto PA, Wani K, Lazar AJ, Tetzlaff MT, Hudgens CW, Callahan MK, Adamow M, Postow MA, Ariyan CE, Gaudreau PO, Nezi L, Mihalcioiu C, Elkrief A, Pezo RC, Haydu LE, Simon JM, Tawbi HA, McQuade J, Hwu P, Hwu WJ, Amaria RN, Burton EM, Woodman SE, Watowich S, Diab A, Patel SP, Glitza IC, Wong MK, Zhao L, Zhang J, Ajami NJ, Petrosino J, Jenq RR, Davies MA, Gershenwald JE, Futreal PA, Sharma P, Allison JP, Routy B, Zitvogel L, Wargo JA, Fluckiger A, Raoult D. Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade. Nat Med. 2021 08; 27(8):1432-1441. PMID: 34239137; PMCID: PMC11107795.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    108. Patel RR, Lupo PJ, Bishop AJ, Lin PP, Delclos GL, Lazar AJ, Benjamin RS, Araujo DM. Synovial Sarcoma of the Hand and Foot: An Institutional Review. Am J Clin Oncol. 2021 07 01; 44(7):361-368. PMID: 33927134.
      Citations:    Fields:    Translation:Humans
    109. Cho WC, Wang WL, Ingram DR, Nagarajan P, Curry JL, Ivan D, Lazar AJ, Hwu WJ, Prieto VG, Torres-Cabala CA, Aung PP, Milton DR. Telomerase Reverse Transcriptase Protein Expression Is More Frequent in Acral Lentiginous Melanoma Than in Other Types of Cutaneous Melanoma. Arch Pathol Lab Med. 2021 07 01; 145(7):842-850. PMID: 33053175.
      Citations:    Fields:    Translation:HumansCells
    110. Leske H, Dalgleish R, Lazar AJ, Cree IA, Reifenberger G. A common classification framework for histone sequence alterations in tumours: an expert consensus proposal. J Pathol. 2021 06; 254(2):109-120. PMID: 33779999.
      Citations: 2     Fields:    Translation:Humans
    111. Tolwani A, Matusiak M, Bui N, Varma S, Baratto L, Iagaru A, Lazar AJ, van de Rijn M, Przybyl J, Forg? E. Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma. NPJ Genom Med. 2021 May 03; 6(1):30. PMID: 33941787; PMCID: PMC8093268.
      Citations: 1     
    112. Wagner MJ, Lyons YA, Siedel JH, Dood R, Nagaraja AS, Haemmerle M, Mangala LS, Chanana P, Lazar AJ, Wang WL, Ravi V, Holland EC, Sood AK. Combined VEGFR and MAPK pathway inhibition in angiosarcoma. Sci Rep. 2021 04 30; 11(1):9362. PMID: 33931674; PMCID: PMC8087824.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    113. Schaefer IM, Lundberg MZ, Demicco EG, Przybyl J, Matusiak M, Ingram DR, Hornick JL, Wang WL, Bauer S, Baker LH, Lazar AJ, van de Rijn M, Fletcher JA, Chibon F, Mari?o-Enr?quez A. Relationships between highly recurrent tumor suppressor alterations in 489 leiomyosarcomas. Cancer. 2021 08 01; 127(15):2666-2673. PMID: 33788262; PMCID: PMC8277678.
      Citations: 3     Fields:    Translation:Humans
    114. Warmke LM, Tinkham EG, Ingram DR, Lazar AJ, Panse G, Wang WL. INSM1 Expression in Angiosarcoma. Am J Clin Pathol. 2021 03 15; 155(4):575-580. PMID: 33210141.
      Citations: 2     Fields:    Translation:Humans
    115. Landry JP, Schertz KL, Chiang YJ, Bhalla AD, Yi M, Keung EZ, Scally CP, Feig BW, Hunt KK, Roland CL, Guadagnolo A, Bishop AJ, Lazar AJ, Slopis JM, McCutcheon IE, Torres KE. Comparison of Cancer Prevalence in Patients With Neurofibromatosis Type 1 at an Academic Cancer Center vs in the General Population From 1985 to 2020. JAMA Netw Open. 2021 03 01; 4(3):e210945. PMID: 33734413; PMCID: PMC7974640.
      Citations: 8     Fields:    Translation:Humans
    116. Ding Z, Ogata D, Roszik J, Qin Y, Kim SH, Tetzlaff MT, Lazar AJ, Davies MA, Ekmekcioglu S, Grimm EA. iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation. Front Oncol. 2021; 11:631766. PMID: 33643925; PMCID: PMC7907506.
      Citations: 2     
    117. Rathore R, Caldwell KE, Schutt C, Brashears CB, Prudner BC, Ehrhardt WR, Leung CH, Lin H, Daw NC, Beird HC, Giles A, Wang WL, Lazar AJ, Chrisinger JSA, Livingston JA, Van Tine BA. Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma. Cell Rep. 2021 01 26; 34(4):108678. PMID: 33503424; PMCID: PMC8552368.
      Citations: 9     Fields:    Translation:HumansCells
    118. Fischer GM, Guerrieri RA, Hu Q, Joon AY, Kumar S, Haydu LE, McQuade JL, Vashisht Gopal YN, Knighton B, Deng W, Hudgens CW, Lazar AJ, Tetzlaff MT, Davies MA. Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdaa177. PMID: 33575655; PMCID: PMC7865080.
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    119. Wang R, Dang M, Harada K, Han G, Wang F, Pool Pizzi M, Zhao M, Tatlonghari G, Zhang S, Hao D, Lu Y, Zhao S, Badgwell BD, Blum Murphy M, Shanbhag N, Estrella JS, Roy-Chowdhuri S, Abdelhakeem AAF, Wang Y, Peng G, Hanash S, Calin GA, Song X, Chu Y, Zhang J, Li M, Chen K, Lazar AJ, Futreal A, Song S, Ajani JA, Wang L. Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma. Nat Med. 2021 01; 27(1):141-151. PMID: 33398161; PMCID: PMC8074162.
      Citations: 30     Fields:    Translation:HumansCells
    120. Boyce-Fappiano D, Guadagnolo BA, Ratan R, Wang WL, Wagner MJ, Patel S, Livingston JA, Lin PP, Diao K, Mitra D, Farooqi A, Lazar AJ, Roland CL, Bishop AJ. Evaluating the Soft Tissue Sarcoma Paradigm for the Local Management of Extraskeletal Ewing Sarcoma. Oncologist. 2021 03; 26(3):250-260. PMID: 33289298; PMCID: PMC7930399.
      Citations: 3     Fields:    Translation:Humans
    121. Washington MK, Goldberg RM, Chang GJ, Limburg P, Lam AK, Salto-Tellez M, Arends MJ, Nagtegaal ID, Klimstra DS, Rugge M, Schirmacher P, Lazar AJ, Odze RD, Carneiro F, Fukayama M, Cree IA, WHO Classification of Tumours Editorial Board. Diagnosis of digestive system tumours. Int J Cancer. 2021 03 01; 148(5):1040-1050. PMID: 32674220.
      Citations: 6     Fields:    Translation:Humans
    122. Qin Y, Bollin K, de Macedo MP, Carapeto F, Kim KB, Roszik J, Wani KM, Reuben A, Reddy ST, Williams MD, Tetzlaff MT, Wang WL, Gombos DS, Esmaeli B, Lazar AJ, Hwu P, Patel SP. Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy. J Immunother Cancer. 2020 11; 8(2). PMID: 33203661; PMCID: PMC7674090.
      Citations: 16     Fields:    Translation:Humans
    123. Ramani NS, Chen H, Broaddus RR, Lazar AJ, Luthra R, Medeiros LJ, Patel KP, Rashid A, Routbort MJ, Stewart J, Tang Z, Bassett R, Manekia J, Barkoh BA, Dang H, Roy-Chowdhuri S. Utilization of cytology smears improves success rates of RNA-based next-generation sequencing gene fusion assays for clinically relevant predictive biomarkers. Cancer Cytopathol. 2021 05; 129(5):374-382. PMID: 33119213.
      Citations: 2     Fields:    Translation:Humans
    124. Landers SM, Bhalla AD, Ma X, Lusby K, Ingram D, Al Sannaa G, Wang WL, Lazar AJ, Torres KE. AXL Inhibition Enhances MEK Inhibitor Sensitivity in Malignant Peripheral Nerve Sheath Tumors. J Cancer Sci Clin Ther. 2020; 4(4):511-525. PMID: 33283192; PMCID: PMC7717506.
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    125. Maitituoheti M, Keung EZ, Tang M, Yan L, Alam H, Han G, Singh AK, Raman AT, Terranova C, Sarkar S, Orouji E, Amin SB, Sharma S, Williams M, Samant NS, Dhamdhere M, Zheng N, Shah T, Shah A, Axelrad JB, Anvar NE, Lin YH, Jiang S, Chang EQ, Ingram DR, Wang WL, Lazar A, Lee MG, Muller F, Wang L, Ying H, Rai K. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma. Cell Rep. 2020 10 20; 33(3):108293. PMID: 33086062; PMCID: PMC7649750.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    126. Cree IA, Indave Ruiz BI, Zavadil J, McKay J, Olivier M, Kozlakidis Z, Lazar AJ, Hyde C, Holdenrieder S, Hastings R, Rajpoot N, Rous B, Zenklusen JC, Normanno N, Schilsky RL, IC3R participants, de la Fouchardiere A. The International Collaboration for Cancer Classification and Research. Int J Cancer. 2021 02 01; 148(3):560-571. PMID: 32818326; PMCID: PMC7756795.
      Citations: 6     Fields:    Translation:Humans
    127. Panse G, Mito JK, Ingram DR, Wani K, Khan S, Lazar AJ, Doyle LA, Wang WL. Radiation-associated sarcomas other than malignant peripheral nerve sheath tumours demonstrate loss of histone H3K27 trimethylation?. Histopathology. 2021 Jan; 78(2):321-326. PMID: 32735735.
      Citations: 4     Fields:    Translation:HumansCells
    128. Fischer GM, Carapeto FCL, Joon AY, Haydu LE, Chen H, Wang F, Van Arnam JS, McQuade JL, Wani K, Kirkwood JM, Thompson JF, Tetzlaff MT, Lazar AJ, Tawbi HA, Gershenwald JE, Scolyer RA, Long GV, Davies MA. Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker. Cancer Med. 2020 11; 9(22):8650-8661. PMID: 33016647; PMCID: PMC7666738.
      Citations: 4     Fields:    Translation:HumansCells
    129. Demetri GD, Antonescu CR, Bjerkehagen B, Boye K, Dei Tos AP, Desai J, Fletcher JA, Gelderblom H, George S, Gronchi A, Haas RL, Hindi N, Hohenberger P, Joensuu H, Jones RL, Judson I, Kang YK, Kawai A, Lazar AJ, Le Cesne A, Maestro R, Maki RG, Patel S, Penault-Llorca F, Premanand Raut C, Rutkowski P, Safwat A, Sbaraglia M, Schaefer IM, Shen L, Serrano C, Stacchiotti S, Sundby Hall K, Tap WD, Thomas DM, Trent J, Valverde C, van der Graaf WTA, von Mehren M, Wagner A, Naito Y, Zalcberg J, Bov?e JVMG, Chac?n M, Mart?n J, Sch?ffski P, Wardelmann E, Blay JY. Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network. Ann Oncol. 2020 11; 31(11):1506-1517. PMID: 32891793; PMCID: PMC7985805.
      Citations: 22     Fields:    Translation:Humans
    130. Tan PH, Ellis I, Allison K, Brogi E, Fox SB, Lakhani S, Lazar AJ, Morris EA, Sahin A, Salgado R, Sapino A, Sasano H, Schnitt S, van Diest P, White VA, Lokuhetty D, Cree IA, WHO Classification of Tumours Editorial Board, Sotiriou C. The 2019 World Health Organization classification of tumours of the breast. Histopathology. 2020 08; 77(2):181-185. PMID: 32056259.
      Citations: 84     Fields:    Translation:Humans
    131. Amin HM, Morani AC, Daw NC, Lamhamedi-Cherradi SE, Subbiah V, Menegaz BA, Vishwamitra D, Eskandari G, George B, Benjamin RS, Patel S, Song J, Lazar AJ, Wang WL, Kurzrock R, Pappo A, Anderson PM, Schwartz GK, Araujo D, Cuglievan B, Ratan R, McCall D, Mohiuddin S, Livingston JA, Molina ER, Naing A, Ludwig JA. IGF-1R/mTOR Targeted Therapy for Ewing Sarcoma: A Meta-Analysis of Five IGF-1R-Related Trials Matched to Proteomic and Radiologic Predictive Biomarkers. Cancers (Basel). 2020 Jul 02; 12(7). PMID: 32630797; PMCID: PMC7408058.
      Citations: 10     
    132. Huang J, Sachdeva M, Xu E, Robinson TJ, Luo L, Ma Y, Williams NT, Lopez O, Cervia LD, Yuan F, Qin X, Zhang D, Owzar K, Gokgoz N, Seto A, Okada T, Singer S, Andrulis IL, Wunder JS, Lazar AJ, Rubin BP, Pipho K, Mello SS, Giudice J, Kirsch DG. The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways. Mol Cancer Res. 2020 10; 18(10):1534-1544. PMID: 32561656; PMCID: PMC7541426.
      Citations: 5     Fields:    Translation:HumansCells
    133. Amgad M, Stovgaard ES, Balslev E, Thagaard J, Chen W, Dudgeon S, Sharma A, Kerner JK, Yuan Y, AbdulJabbar K, Savas P, Voorwerk L, Beck AH, Madabhushi A, Hartman J, Sebastian MM, Horlings HM, Hudecek J, Ciompi F, Moore DA, Singh R, Mathieu MC, Lennerz JK, Kirtani P, Chen IC, Braybrooke JP, Pruneri G, Demaria S, Adams S, Schnitt SJ, Lakhani SR, Badve SS, Khojasteh M, Symmans WF, Gonzalez-Ericsson P, Pogue-Geile KL, Kim RS, Rimm DL, Viale G, Hewitt SM, Bartlett JMS, Goel S, Lien HC, Loibl S, Kos Z, Loi S, Hanna MG, Michiels S, Kok M, Nielsen TO, Lazar AJ, Bago-Horvath Z, Kooreman LFS, van der Laak JAWM, Saltz J, Gallas BD, Kurkure U, Barnes M, Salgado R, Cooper LAD, International Immuno-Oncology Biomarker Working Group, Denkert C, Wienert S, Roblin E, Balancin ML, Rojo F, Comerma L, Sotiriou C, Penault-Llorca F. Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group. NPJ Breast Cancer. 2020; 6:16. PMID: 32411818; PMCID: PMC7217824.
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    134. Kos Z, Roblin E, Kim RS, Michiels S, Gallas BD, Chen W, van de Vijver KK, Goel S, Adams S, Demaria S, Viale G, Nielsen TO, Badve SS, Symmans WF, Rimm DL, Hewitt S, Loibl S, Luen SJ, Bartlett JMS, Savas P, Pruneri G, Dillon DA, Cheang MCU, Tutt A, Hall JA, Kok M, Horlings HM, Madabhushi A, van der Laak J, Ciompi F, Gruosso T, Fox SB, Araya JC, Floris G, Hudecek J, Voorwerk L, Beck AH, Kerner J, Larsimont D, Declercq S, Van den Eynden G, Pusztai L, Yang W, AbdulJabbar K, Yuan Y, Singh R, Hiley C, Bakir MA, Lazar AJ, Naber S, Castillo M, Curigliano G, Dieci MV, Swanton C, Reis-Filho J, Sparano J, Balslev E, Chen IC, Stovgaard EIS, Pogue-Geile K, Blenman KRM, Schnitt S, Lakhani SR, Braybrooke JP, Hanna MG, Bethmann D, Castaneda CA, Sharma A, Lien HC, Fineberg S, Comerma L, Gonzalez-Ericsson P, Brogi E, Loi S, Saltz J, Cooper L, Amgad M, Moore DA, Salgado R, International Immuno-Oncology Biomarker Working Group, Sotiriou C, Denkert C, Laenkholm AV, Bellolio E, Ehinger A, Wienert S, Andr? F, Penault-Llorca F, Vincent-Salomon A, Rojo F, Soler-Mons? MT, Willard-Gallo K, Thagaard J, Klaushen F. Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer. NPJ Breast Cancer. 2020; 6:17. PMID: 32411819; PMCID: PMC7217863.
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    135. Carrot-Zhang J, Chambwe N, Damrauer JS, Knijnenburg TA, Robertson AG, Yau C, Zhou W, Berger AC, Huang KL, Newberg JY, Mashl RJ, Romanel A, Sayaman RW, Demichelis F, Felau I, Frampton GM, Han S, Hoadley KA, Kemal A, Laird PW, Lazar AJ, Le X, Oak N, Shen H, Wong CK, Zenklusen JC, Ziv E, Cancer Genome Atlas Analysis Network, Cherniack AD, Beroukhim R. Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer. Cancer Cell. 2020 05 11; 37(5):639-654.e6. PMID: 32396860; PMCID: PMC7328015.
      Citations: 56     Fields:    Translation:HumansCells
    136. Bishop AJ, Landry JP, Roland CL, Ratan R, Feig BW, Moon BS, Zarzour MA, Wang WL, Lazar AJ, Lewis VO, Torres KE, Guadagnolo BA. Certain risk factors for patients with desmoid tumors warrant reconsideration of local therapy strategies. Cancer. 2020 07 15; 126(14):3265-3273. PMID: 32343846; PMCID: PMC7748083.
      Citations: 4     Fields:    Translation:Humans
    137. Barnhill R, van Dam PJ, Vermeulen P, Champenois G, Rawson RV, Wilmott JS, Thompson JF, Long GV, Roman-Roman S, Busam KJ, Scolyer RA, Lazar AJ, Lugassy C, Nicolas A, Cassoux N. Replacement and desmoplastic histopathological growth patterns in cutaneous melanoma liver metastases: frequency, characteristics, and robust prognostic value. J Pathol Clin Res. 2020 07; 6(3):195-206. PMID: 32304183; PMCID: PMC7339161.
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    138. Mitra A, Andrews MC, Roh W, De Macedo MP, Hudgens CW, Carapeto F, Singh S, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S, Ng KS, Schalck A, Sakellariou-Thompson DA, Chen E, Reddy SM, Spencer CN, Wiesnoski D, Little LD, Gumbs C, Cooper ZA, Burton EM, Hwu P, Davies MA, Zhang J, Bernatchez C, Navin N, Sharma P, Allison JP, Wargo JA, Yee C, Tetzlaff MT, Hwu WJ, Lazar AJ, Futreal PA. Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nat Commun. 2020 04 15; 11(1):1839. PMID: 32296058; PMCID: PMC7160105.
      Citations: 5     Fields:    Translation:Humans
    139. Gonzalez-Ericsson PI, Stovgaard ES, Reisenbichler E, Kos Z, Carter JM, Le Quesne J, Nielsen TO, Laenkholm AV, Fox SB, Adam J, Bartlett JM, Rimm DL, Quinn C, Peeters D, Dieci MV, Vincent-Salomon A, Cree I, Hida AI, Balko JM, Haynes HR, Frahm I, Bellolio E, Yang W, Kirtani P, Sugie T, Ehinger A, Kok M, McArthur H, Siziopikou K, Badve S, Fineberg S, Gown A, Viale G, Schnitt SJ, Pruneri G, Penault-Llorca F, Hewitt S, Thompson EA, Allison KH, Symmans WF, Bellizzi AM, Brogi E, Moore DA, Dillon DA, Lazar A, Lien H, Goetz MP, Broeckx G, El Bairi K, Harbeck N, Cimino-Mathews A, Adams S, Liu SW, Loibl S, Chen IC, Lakhani SR, Juco JW, Blackley EF, Demaria S, Leon-Ferre R, Zardavas D, Emancipator K, Ely S, Loi S, Salgado R, Sanders M, International Immuno-Oncology Biomarker Working Group, Sua LF, Michiels S, Acosta-Haab G, Balancin M, Castaneda CA, Larsimont D, Sotiriou C, Denkert C, Gluz O. The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice. J Pathol. 2020 04; 250(5):667-684. PMID: 32129476.
      Citations: 52     Fields:    Translation:HumansCells
    140. Ali AMR, Tsai JW, Leung CH, Lin H, Ravi V, Conley AP, Lazar AJ, Wang WL, Nathenson MJ. The immune microenvironment of uterine adenosarcomas. Clin Sarcoma Res. 2020; 10:5. PMID: 32231779; PMCID: PMC7103067.
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    141. Groisberg R, Roszik J, Conley AP, Lazar AJ, Portal DE, Hong DS, Naing A, Herzog CE, Somaiah N, Zarzour MA, Patel S, Brown RE, Subbiah V. Genomics, Morphoproteomics, and Treatment Patterns of Patients with Alveolar Soft Part Sarcoma and Response to Multiple Experimental Therapies. Mol Cancer Ther. 2020 05; 19(5):1165-1172. PMID: 32127467; PMCID: PMC8386165.
      Citations: 4     Fields:    Translation:Humans
    142. Ballester LY, Meis JM, Lazar AJ, Prabhu SS, Hoang KB, Leeds NE, Fuller GN. Intracranial Myxoid Mesenchymal Tumor With EWSR1-ATF1 Fusion. J Neuropathol Exp Neurol. 2020 03 01; 79(3):347-351. PMID: 32016322.
      Citations: 11     Fields:    Translation:HumansCells
    143. Wu CC, Beird HC, Andrew Livingston J, Advani S, Mitra A, Cao S, Reuben A, Ingram D, Wang WL, Ju Z, Hong Leung C, Lin H, Zheng Y, Roszik J, Wang W, Patel S, Benjamin RS, Somaiah N, Conley AP, Mills GB, Hwu P, Gorlick R, Lazar A, Daw NC, Lewis V, Futreal PA. Immuno-genomic landscape of osteosarcoma. Nat Commun. 2020 02 21; 11(1):1008. PMID: 32081846; PMCID: PMC7035358.
      Citations: 59     Fields:    Translation:Humans
    144. El Beaino M, Jupiter DC, Assi T, Rassy E, Lazar AJ, Araujo DM, Lin PP. Diagnostic Value of TLE1 in Synovial Sarcoma: A Systematic Review and Meta-Analysis. Sarcoma. 2020; 2020:7192347. PMID: 32322158; PMCID: PMC7166261.
      Citations: 5     
    145. Haydu LE, Lo SN, McQuade JL, Amaria RN, Wargo J, Ross MI, Cormier JN, Lucci A, Lee JE, Ferguson SD, Saw RPM, Spillane AJ, Shannon KF, Stretch JR, Hwu P, Patel SP, Diab A, Wong MKK, Glitza Oliva IC, Tawbi H, Carlino MS, Menzies AM, Long GV, Lazar AJ, Tetzlaff MT, Scolyer RA, Gershenwald JE, Thompson JF, Davies MA. Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma. J Clin Oncol. 2020 05 01; 38(13):1429-1441. PMID: 31990608; PMCID: PMC7193747.
      Citations: 5     Fields:    Translation:Humans
    146. Chopra S, Lazar AJ, Wang WL. Are ALK rearrangements found in smooth muscle tumours of the gastrointestinal tract? Histopathology. 2020 03; 76(4):627-628. PMID: 31596959.
      Citations:    Fields:    Translation:Humans
    147. Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, Cogdill AP, Liu W, LeBleu VS, Kugeratski FG, Patel S, Davies MA, Hwu P, Lee JE, Gershenwald JE, Lucci A, Arora R, Woodman S, Keung EZ, Gaudreau PO, Reuben A, Spencer CN, Burton EM, Haydu LE, Lazar AJ, Zapassodi R, Hudgens CW, Ledesma DA, Ong S, Bailey M, Warren S, Rao D, Krijgsman O, Rozeman EA, Peeper D, Blank CU, Schumacher TN, Butterfield LH, Zelazowska MA, McBride KM, Kalluri R, Allison J, Petitprez F, Fridman WH, Hacohen N, Rezvani K, Sharma P, Tetzlaff MT, Wang L, Wargo JA, Saut?s-Fridman C. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020 01; 577(7791):549-555. PMID: 31942075; PMCID: PMC8762581.
      Citations: 512     Fields:    Translation:HumansCells
    148. Petitprez F, Keung EZ, Chen TW, Sun CM, Calderaro J, Jeng YM, Hsiao LP, Lacroix L, Moreira M, Lacroix G, Natario I, Adam J, Burgess MA, Bolejack V, Reinke D, Wani KM, Wang WL, Lazar AJ, Roland CL, Wargo JA, Tawbi HA, Fridman WH, de Reyni?s A, Bougo?in A, Lucchesi C, Laizet YH, Toulmonde M, Italiano A, Saut?s-Fridman C. B cells are associated with survival and immunotherapy response in sarcoma. Nature. 2020 01; 577(7791):556-560. PMID: 31942077.
      Citations: 441     Fields:    Translation:HumansCells
    149. Keung EZ, Burgess M, Salazar R, Parra ER, Rodrigues-Canales J, Bolejack V, Van Tine BA, Schuetze SM, Attia S, Riedel RF, Hu J, Okuno SH, Priebat DA, Movva S, Davis LE, Reed DR, Reuben A, Roland CL, Reinke D, Lazar AJ, Wang WL, Wargo JA, Tawbi HA. Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab. Clin Cancer Res. 2020 03 15; 26(6):1258-1266. PMID: 31900276; PMCID: PMC7731262.
      Citations: 49     Fields:    Translation:HumansCellsCTClinical Trials
    150. Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S, Lazar AJ, Pant S, Meric-Bernstam F. Overview of the TREC 2019 Precision Medicine Track. Text Retr Conf. 2019 Nov; 1250. PMID: 34849512; PMCID: PMC8629155.
      Citations: 1     
    151. Bishop AJ, Bird JE, Conley AP, Roland CL, Moon BS, Satcher RL, Livingston JA, Patel S, Wang WL, Lazar AJ, Lewis VO, Lin PP, Guadagnolo BA. Extraskeletal Myxoid Chondrosarcomas: Combined Modality Therapy With Both Radiation and Surgery Improves Local Control. Am J Clin Oncol. 2019 10; 42(10):744-748. PMID: 31436747; PMCID: PMC7771031.
      Citations: 5     Fields:    Translation:Humans
    152. Molina ER, Chim LK, Salazar MC, Mehta SM, Menegaz BA, Lamhamedi-Cherradi SE, Satish T, Mohiuddin S, McCall D, Zaske AM, Cuglievan B, Lazar AJ, Scott DW, Grande-Allen JK, Ludwig JA, Mikos AG. Mechanically tunable coaxial electrospun models of YAP/TAZ mechanoresponse and IGF-1R activation in osteosarcoma. Acta Biomater. 2019 12; 100:38-51. PMID: 31542501; PMCID: PMC7027943.
      Citations: 14     Fields:    Translation:HumansCells
    153. Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Disis ML, Vincent BG, Shmulevich I, Thorsson V, Malta TM, Noushmehr H, Demicco EG. The Immune Landscape of Cancer. Immunity. 2019 Aug 20; 51(2):411-412. PMID: 31433971.
      Citations: 119     Fields:    
    154. Nagarajan P, Piao J, Ning J, Noordenbos LE, Curry JL, Torres-Cabala CA, Diwan AH, Ivan D, Aung PP, Ross MI, Royal RE, Wargo JA, Wang WL, Samdani R, Lazar AJ, Rashid A, Davies MA, Prieto VG, Gershenwald JE, Tetzlaff MT. Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features. Mod Pathol. 2020 03; 33(3):496-513. PMID: 31383963.
      Citations: 4     Fields:    Translation:Humans
    155. Bonvalot S, Rutkowski PL, Ducassou A, Hong A, Mervoyer A, Rastrelli M, Li RK, Herraez AC, Gronchi A, Sy-Ortin T, Hohenberger P, Le Cesne A, Helfre S, Saada-Bouzid E, Borkowska A, Anghel R, Co A, Gebhart M, Montero A, Loong HH, Lapeire L, Dema S, Kacso G, Austen L, Moureau-Zabotto L, Servois V, Terrier P, Lazar AJ, Papai Z, Thariat J, Carr?re S, Sunyach MP, Agoston P, Moreno V, Tiangco B, Mangel L, de Ba?re T, Kantor G, Verg?s R, Wardelmann E, Bov?e JVMG, Le P?choux C. NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2-3, randomised, controlled trial. Lancet Oncol. 2019 08; 20(8):1148-1159. PMID: 31296491.
      Citations: 71     Fields:    Translation:HumansCTClinical Trials
    156. Chrisinger JSA, Al-Zaid T, Keung EZ, Leung C, Lin HY, Roland CL, Torres KE, Benjamin RS, Ingram DR, Khan S, Somaiah N, Amini B, Feig BW, Lazar AJ, Wang WL. The degree of sclerosis is associated with prognosis in well-differentiated liposarcoma of the retroperitoneum. J Surg Oncol. 2019 Sep; 120(3):382-388. PMID: 31206726; PMCID: PMC7652035.
      Citations:    Fields:    Translation:Humans
    157. Conley AP, Wang WL, Livingston JA, Ravi V, Tsai JW, Ali A, Ingram DR, Lowery CD, Roland CL, Somaiah N, Hwu P, Yee C, Subbiah V, Futreal A, Lazar AJ, Patel S, Roszik J. MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma. Cancers (Basel). 2019 May 15; 11(5). PMID: 31096717; PMCID: PMC6562561.
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    158. Task Force/Committee Members, Vidal CI, Sutton A, Armbrect EA, Lee JB, Litzner BR, Hurley MY, Rating Panel, Alam M, Duncan LM, Elston DM, Ferringer T, Fung MA, Hosler GA, Lazar AJ, Lowe L, Plaza JA, Robinson JK, Schaffer A, Emanuel PO. Muir-Torre syndrome appropriate use criteria: Effect of patient age on appropriate use scores. J Cutan Pathol. 2019 Jul; 46(7):484-489. PMID: 30895633.
      Citations: 1     Fields:    Translation:Humans
    159. Moncur JT, Bartley AN, Bridge JA, Kamel-Reid S, Lazar AJ, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Kim AS. Performance Comparison of Different Analytic Methods in Proficiency Testing for Mutations in the BRAF, EGFR, and KRAS Genes: A Study of the College of American Pathologists Molecular Oncology Committee. Arch Pathol Lab Med. 2019 10; 143(10):1203-1211. PMID: 30969158.
      Citations: 1     Fields:    Translation:Humans
    160. Erstine EM, Lazar AJ. Toward an effective use of ?-catenin immunohistochemistry in the evaluation of challenging melanocytic lesions. Virchows Arch. 2019 05; 474(5):535-537. PMID: 30868296.
      Citations: 2     Fields:    Translation:Humans
    161. Bishop AJ, Livingston JA, Araujo DM, Moon BS, Patel S, Wang WL, Lazar AJ, Roland CL, Guadagnolo BA. Extraskeletal Osteosarcomas: A Case Made for Combined Modality Local Therapy With Radiation and Surgery. Am J Clin Oncol. 2019 03; 42(3):238-242. PMID: 30614820.
      Citations: 3     Fields:    Translation:Humans
    162. Aung PP, Parra ER, Barua S, Sui D, Ning J, Mino B, Ledesma DA, Curry JL, Nagarajan P, Torres-Cabala CA, Efstathiou E, Hoang AG, Wong MK, Wargo JA, Lazar AJ, Rao A, Prieto VG, Wistuba I, Tetzlaff MT. B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density. Clin Cancer Res. 2019 06 01; 25(11):3455-3467. PMID: 30808776; PMCID: PMC8211110.
      Citations: 9     Fields:    Translation:HumansCells
    163. Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA, de Macedo MP. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov. 2019 05; 9(5):628-645. PMID: 30787016; PMCID: PMC6497554.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    164. Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G, Malouf GG, Sgambato A. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019 02 11; 35(2):204-220.e9. PMID: 30753823; PMCID: PMC7876656.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    165. Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A, Raju GS, Stroehlein JR, Campbell MT, Gao J, Subudhi SK, Maru DM, Blando JM, Lazar AJ, Allison JP, Sharma P, Tetzlaff MT, Wargo JA, Jenq RR. Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis. Nat Med. 2019 Jan; 25(1):188. PMID: 30479380.
      Citations: 2     Fields:    
    166. Bishop AJ, Zarzour MA, Ratan R, Torres KE, Feig BW, Wang WL, Lazar AJ, Moon BS, Roland CL, Guadagnolo BA. Long-Term Outcomes for Patients With Desmoid Fibromatosis Treated With Radiation Therapy: A 10-Year Update and Re-evaluation of the Role of Radiation Therapy for Younger Patients. Int J Radiat Oncol Biol Phys. 2019 04 01; 103(5):1167-1174. PMID: 30552963.
      Citations: 4     Fields:    Translation:Humans
    167. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA, Milton DR. Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 Dec; 24(12):1941. PMID: 30361510.
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    168. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA, Milton DR. Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 Dec; 24(12):1942. PMID: 30361511.
      Citations: 5     Fields:    
    169. Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A, Raju GS, Stroehlein JR, Campbell MT, Gao J, Subudhi SK, Maru DM, Blando JM, Lazar AJ, Allison JP, Sharma P, Tetzlaff MT, Wargo JA, Jenq RR. Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis. Nat Med. 2018 12; 24(12):1804-1808. PMID: 30420754; PMCID: PMC6322556.
      Citations: 183     Fields:    Translation:HumansCells
    170. Merker JD, Devereaux K, Iafrate AJ, Kamel-Reid S, Kim AS, Moncur JT, Montgomery SB, Nagarajan R, Portier BP, Routbort MJ, Smail C, Surrey LF, Vasalos P, Lazar AJ, Lindeman NI. Proficiency Testing of Standardized Samples Shows Very High Interlaboratory Agreement for Clinical Next-Generation Sequencing-Based Oncology Assays. Arch Pathol Lab Med. 2019 04; 143(4):463-471. PMID: 30376374; PMCID: PMC6910717.
      Citations: 13     Fields:    Translation:Humans
    171. McKean M, Oba J, Ma J, Roth KG, Wang WL, Carapeto FCL, Haydu LE, Siroy AE, Vo P, Hong DS, Eterovic AK, Patel KP, Bassett RL, Grimm EA, Lazar AJ, Woodman SE, Macedo MP. Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma. J Invest Dermatol. 2019 03; 139(3):728-731. PMID: 30798855.
      Citations: 4     Fields:    Translation:Humans
    172. Aires DJ, Yoshida M, Richardson SK, Bai M, Liu L, Moreno R, Lazar AJF, Wick JA, Rich BE, Murphy G, Blumberg RS, Fuhlbrigge RC, Kupper TS. T-cell trafficking plays an essential role in tumor immunity. Lab Invest. 2019 01; 99(1):85-92. PMID: 30353131; PMCID: PMC6309214.
      Citations: 1     Fields:    Translation:AnimalsCells
    173. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA, Milton DR. Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 11; 24(11):1649-1654. PMID: 30297909; PMCID: PMC6481682.
      Citations: 220     Fields:    Translation:HumansCTClinical Trials
    174. Keung EZ, Lazar AJ, Torres KE, Wang WL, Cormier JN, Ashleigh Guadagnolo B, Bishop AJ, Lin H, Hunt KK, Bird J, Lewis VO, Patel SR, Wargo JA, Somaiah N, Roland CL. Phase II study of neoadjuvant checkpoint blockade in patients with surgically resectable undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma. BMC Cancer. 2018 Sep 24; 18(1):913. PMID: 30249211; PMCID: PMC6154892.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    175. Roszik J, Ring KL, Wani KM, Lazar AJ, Yemelyanova AV, Soliman PT, Frumovitz M, Jazaeri AA. Gene Expression Analysis Identifies Novel Targets for Cervical Cancer Therapy. Front Immunol. 2018; 9:2102. PMID: 30283446; PMCID: PMC6156434.
      Citations: 13     Fields:    Translation:HumansCells
    176. Demicco EG, Wani K, Ingram D, Wagner M, Maki RG, Rizzo A, Meeker A, Lazar AJ, Wang WL. TERT promoter mutations in solitary fibrous tumour. Histopathology. 2018 Nov; 73(5):843-851. PMID: 29985536.
      Citations: 13     Fields:    Translation:HumansCells
    177. Liu Y, Weber Z, San Lucas FA, Deshpande A, Jakubek YA, Sulaiman R, Fagerness M, Flier N, Sulaiman J, Davis CM, Fowler J, Starks D, Rojas-Espaillat L, Lazar AJ, Davies GE, Ehli EA, Scheet P. Assessing inter-component heterogeneity of biphasic uterine carcinosarcomas. Gynecol Oncol. 2018 11; 151(2):243-249. PMID: 30194005; PMCID: PMC6214727.
      Citations: 6     Fields:    Translation:Humans
    178. Nathenson MJ, Conley AP, Lin H, Fleming N, Lazar A, Wang WL, Ravi V. The Importance of Lymphovascular Invasion in Uterine Adenosarcomas: Analysis of Clinical, Prognostic, and Treatment Outcomes. Int J Gynecol Cancer. 2018 09; 28(7):1297-1310. PMID: 30044322.
      Citations: 3     Fields:    Translation:Humans
    179. Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Kwok-Shing Ng P, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, MC3 Working Group, Cancer Genome Atlas Research Network, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L, Cort?s-Ciriano I. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018 08 09; 174(4):1034-1035. PMID: 30096302; PMCID: PMC8045146.
      Citations: 173     Fields:    
    180. Charville GW, Lazar AJ. Prognostic gene expression signatures in sarcoma: finding clarity in complexity. Ann Oncol. 2018 08 01; 29(8):1632-1633. PMID: 29982358.
      Citations:    Fields:    Translation:HumansCells
    181. Charville GW, Wang WL, Ingram DR, Roy A, Thomas D, Patel RM, Hornick JL, van de Rijn M, Lazar AJ. PAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation. Mod Pathol. 2019 01; 32(1):154-156. PMID: 29985454.
      Citations: 5     Fields:    Translation:Humans
    182. Kwong LN, De Macedo MP, Haydu L, Joon AY, Tetzlaff MT, Calderone TL, Wu CJ, Kwong MK, Roszik J, Hess KR, Davies MA, Lazar AJ, Gershenwald JE. Biological Validation of RNA Sequencing Data from Formalin-Fixed Paraffin-Embedded Primary Melanomas. JCO Precis Oncol. 2018; 2018. PMID: 31058252; PMCID: PMC6498859.
      Citations: 10     Fields:    
    183. Vidal CI, Armbrect EA, Andea AA, Bohlke AK, Comfere NI, Hughes SR, Kim J, Kozel JA, Lee JB, Linos K, Litzner BR, Missall TA, Novoa RA, Sundram U, Swick BL, Hurley MY, Alam M, Argenyi Z, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA, Lazar AJ, Lowe L, Plaza JA, Prieto VG, Robinson JK, Schaffer A, Subtil A, Wang WL. Appropriate use criteria in dermatopathology: Initial recommendations from the American Society of Dermatopathology. J Cutan Pathol. 2018 Aug; 45(8):563-580. PMID: 29566273.
      Citations: 3     Fields:    Translation:Humans
    184. Subbiah V, Lamhamedi-Cherradi SE, Cuglievan B, Menegaz BA, Camacho P, Huh W, Ramamoorthy V, Anderson PM, Pollock RE, Lev DC, Qiao W, McAleer MF, Benjamin RS, Patel S, Herzog CE, Daw NC, Feig BW, Lazar AJ, Hayes-Jordan A, Ludwig JA. Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival. Clin Cancer Res. 2018 10 01; 24(19):4865-4873. PMID: 29871905; PMCID: PMC6168359.
      Citations: 23     Fields:    Translation:Humans
    185. Oba J, Kim SH, Wang WL, Macedo MP, Carapeto F, McKean MA, Van Arnam J, Eterovic AK, Sen S, Kale CR, Yu X, Haymaker CL, Routbort M, Haydu LE, Bernatchez C, Lazar AJ, Grimm EA, Hong DS, Woodman SE. Targeting the HGF/MET Axis Counters Primary Resistance to KIT Inhibition in KIT-Mutant Melanoma. JCO Precis Oncol. 2018; 2018. PMID: 30094412; PMCID: PMC6080631.
      Citations: 9     Fields:    
    186. Kim AS, Bartley AN, Bridge JA, Kamel-Reid S, Lazar AJ, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Moncur JT. Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing. JAMA Oncol. 2018 06 01; 4(6):838-841. PMID: 29242895; PMCID: PMC6145687.
      Citations: 12     Fields:    Translation:Humans
    187. McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM, Araujo DM, Wang WL, Tsai JW, Yeagley M, Wagner AJ, Futreal PA, Khan J, Lazar AJ, Kadoch C. The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma. Cancer Cell. 2018 06 11; 33(6):1128-1141.e7. PMID: 29861296; PMCID: PMC6791822.
      Citations: 65     Fields:    Translation:HumansCells
    188. Kim G, Kurnit KC, Djordjevic B, Singh C, Munsell MF, Wang WL, Lazar AJ, Zhang W, Broaddus R. Nuclear ?-catenin localization and mutation of the CTNNB1 gene: a context-dependent association. Mod Pathol. 2018 10; 31(10):1553-1559. PMID: 29795437; PMCID: PMC6168348.
      Citations: 29     Fields:    Translation:HumansCells
    189. Bezrookove V, Nosrati M, Miller JR, De Semir D, Dar AA, Vosoughi E, Vaquero E, Sucker A, Lazar AJ, Gershenwald JE, Davies MA, Schadendorf D, Kashani-Sabet M. Role of Elevated PHIP Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma. Clin Cancer Res. 2018 09 01; 24(17):4119-4125. PMID: 29776954; PMCID: PMC6125189.
      Citations: 7     Fields:    Translation:Humans
    190. Chen H, Luthra R, Patel KP, Routbort M, Rashid A, Roy-Chowdhuri S, Lazar A, Broaddus R, Manekia J, Singh RR, Yemelyanova A. Challenges in next generation sequencing analysis of somatic mutations in transplant patients. Cancer Genet. 2018 10; 226-227:17-22. PMID: 30005850.
      Citations:    Fields:    Translation:Humans
    191. Keung EZ, Ikoma N, Benjamin R, Wang WL, Lazar AJ, Feig BW. The clinical behavior of well differentiated liposarcoma can be extremely variable: A retrospective cohort study at a major sarcoma center. J Surg Oncol. 2018 Jun; 117(8):1799-1805. PMID: 29723411; PMCID: PMC6904950.
      Citations: 3     Fields:    Translation:Humans
    192. Task Force/Committee Members, Vidal CI, Armbrect EA, Andea AA, Bohlke AK, Comfere NI, Hughes SR, Kim J, Kozel JA, Lee JB, Linos K, Litzner BR, Missall TA, Novoa RA, Sundram U, Swick BL, Hurley MY, Rating Panel, Alam M, Argenyi Z, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA, Lazar AJ, Lowe L, Plaza JA, Prieto VG, Robinson JK, Schaffer A, Subtil A, Wang WL. Appropriate use criteria in dermatopathology: Initial recommendations from the American Society of Dermatopathology. J Am Acad Dermatol. 2019 Jan; 80(1):189-207.e11. PMID: 29689323.
      Citations: 2     Fields:    Translation:Humans
    193. Somaiah N, Beird HC, Barbo A, Song J, Mills Shaw KR, Wang WL, Eterovic K, Chen K, Lazar A, Conley AP, Ravi V, Hwu P, Futreal A, Simon G, Meric-Bernstam F, Hong D. Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations. Oncotarget. 2018 Apr 13; 9(28):19891-19899. PMID: 29731991; PMCID: PMC5929434.
      Citations: 7     Fields:    
    194. Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Robertson AG, Schneider BG, Lawrence MS, Noushmehr H, Malta TM, Cancer Genome Atlas Network, Stuart JM, Benz CC, Laird PW, Thorsson V, Sanchez-Vega F. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell. 2018 04 05; 173(2):291-304.e6. PMID: 29625048; PMCID: PMC5957518.
      Citations: 682     Fields:    Translation:HumansCells
    195. Mina M, Luna A, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG, Lazar AJ, Hammer GD, Giordano T, Kwong LN, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M, Cancer Genome Atlas Research Network, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Sanchez-Vega F, Armenia J, Chatila WK, La KC, Chakravarty D, Daian F, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Schultz N. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 2018 04 05; 173(2):321-337.e10. PMID: 29625050; PMCID: PMC6070353.
      Citations: 805     Fields:    Translation:HumansCells
    196. Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kaminska B, Huelsken J, Omberg L, Gevaert O, Czerwinska P, Mazurek S, Mishra L, Heyn H, Krasnitz A, Godwin AK, Lazar AJ, Cancer Genome Atlas Research Network, Stuart JM, Hoadley KA, Laird PW, Wiznerowicz M, Malta TM, Colaprico A, Noushmehr H. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell. 2018 04 05; 173(2):338-354.e15. PMID: 29625051; PMCID: PMC5902191.
      Citations: 467     Fields:    Translation:HumansCells
    197. Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Disis ML, Vincent BG, Shmulevich I, Thorsson V, Malta TM, Noushmehr H, Demicco EG. The Immune Landscape of Cancer. Immunity. 2018 04 17; 48(4):812-830.e14. PMID: 29628290; PMCID: PMC5982584.
      Citations: 1407     Fields:    Translation:HumansCells
    198. Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Jayasinghe R, Chen F, Yu L, Sun S, Kim J, Taylor AM, Cherniack AD, Akbani R, Suphavilai C, Nagarajan N, Stuart JM, Mills GB, Wyczalkowski MA, Vincent BG, Hutter CM, Zenklusen JC, Hoadley KA, Wendl MC, Shmulevich L, Lazar AJ, Wheeler DA, Getz G, Cancer Genome Atlas Research Network, Colaprico A, Cort?s-Ciriano I, Olsen C. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell. 2018 04 05; 173(2):305-320.e10. PMID: 29625049; PMCID: PMC5916814.
      Citations: 118     Fields:    Translation:HumansCells
    199. Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Cancer Genome Atlas Research Network, Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L, Reimand J. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell. 2018 04 05; 173(2):355-370.e14. PMID: 29625052; PMCID: PMC5949147.
      Citations: 239     Fields:    Translation:HumansCells
    200. Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, MC3 Working Group, Cancer Genome Atlas Research Network, Lawrence MS, Godzik A, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L, Colaprico A, Cort?s-Ciriano I, Lopez-Bigas N. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018 04 05; 173(2):371-385.e18. PMID: 29625053; PMCID: PMC6029450.
      Citations: 625     Fields:    Translation:Humans
    201. Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, Gevaert O, Prunello M, Shen H, Anur P, Chen J, Cheng H, Hayes DN, Bullman S, Pedamallu CS, Ojesina AI, Sadeghi S, Mungall KL, Robertson AG, Benz C, Schultz A, Kanchi RS, Gay CM, Hegde A, Diao L, Wang J, Ma W, Sumazin P, Chiu HS, Chen TW, Gunaratne P, Donehower L, Rader JS, Zuna R, Al-Ahmadie H, Lazar AJ, Flores ER, Tsai KY, Zhou JH, Rustgi AK, Drill E, Shen R, Wong CK, Cancer Genome Atlas Research Network, Stuart JM, Laird PW, Hoadley KA, Weinstein JN, Peto M, Pickering CR, Chen Z, Van Waes C. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Rep. 2018 04 03; 23(1):194-212.e6. PMID: 29617660; PMCID: PMC6002769.
      Citations: 107     Fields:    Translation:HumansCells
    202. Saltz J, Gupta R, Hou L, Kurc T, Singh P, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J, Cancer Genome Atlas Research Network, Shmulevich I, Rao AUK, Lazar AJ, Sharma A, Thorsson V. Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Rep. 2018 04 03; 23(1):181-193.e7. PMID: 29617659; PMCID: PMC5943714.
      Citations: 239     Fields:    Translation:HumansCells
    203. Gao Q, Liang WW, Foltz SM, Mutharasu G, Jayasinghe RG, Cao S, Liao WW, Reynolds SM, Wyczalkowski MA, Yao L, Yu L, Sun SQ, Fusion Analysis Working Group, Cancer Genome Atlas Research Network, Chen K, Lazar AJ, Fields RC, Wendl MC, Van Tine BA, Vij R, Chen F, Nykter M, Shmulevich I, Ding L. Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Rep. 2018 04 03; 23(1):227-238.e3. PMID: 29617662; PMCID: PMC5916809.
      Citations: 152     Fields:    Translation:HumansCells
    204. Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ, Cancer Genome Atlas Research Network, Cherniack AD, Beroukhim R, Meyerson M. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer Cell. 2018 04 09; 33(4):676-689.e3. PMID: 29622463; PMCID: PMC6028190.
      Citations: 285     Fields:    Translation:HumansCells
    205. Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Cancer Genome Atlas Research Network, Bass AJ, Laird PW, Thorsson V. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer Cell. 2018 04 09; 33(4):721-735.e8. PMID: 29622466; PMCID: PMC5966039.
      Citations: 177     Fields:    Translation:HumansCells
    206. Beird HC, Wu CC, Ingram DR, Wang WL, Alimohamed A, Gumbs C, Little L, Song X, Feig BW, Roland CL, Zhang J, Benjamin RS, Hwu P, Lazar AJ, Futreal PA, Somaiah N. Genomic profiling of dedifferentiated liposarcoma compared to matched well-differentiated liposarcoma reveals higher genomic complexity and a common origin. Cold Spring Harb Mol Case Stud. 2018 04; 4(2). PMID: 29610390; PMCID: PMC5880260.
      Citations: 22     Fields:    Translation:Humans
    207. Berger AC, Korkut A, Kanchi RS, Hegde AM, Lenoir W, Liu W, Liu Y, Fan H, Shen H, Ravikumar V, Rao A, Schultz A, Li X, Sumazin P, Mestdagh P, Gunaratne PH, Yau C, Bowlby R, Robertson AG, Wang C, Cherniack AD, Godwin AK, Kuderer NM, Rader JS, Zuna RE, Sood AK, Lazar AJ, Ojesina AI, Adebamowo C, Adebamowo SN, Baggerly KA, Chen TW, Chiu HS, Lefever S, Liu L, MacKenzie K, Orsulic S, Roszik J, Shelley CS, Song Q, Vellano CP, Wentzensen N, Cancer Genome Atlas Research Network, Weinstein JN, Mills GB, Levine DA, Akbani R, Williams C, Tiezzi DG. A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell. 2018 04 09; 33(4):690-705.e9. PMID: 29622464; PMCID: PMC5959730.
      Citations: 207     Fields:    Translation:Humans
    208. Livingston JA, Wang WL, Tsai JW, Lazar AJ, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M, Gordon NB, Kleinerman ES. Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol Cancer Ther. 2018 06; 17(6):1315-1323. PMID: 29592877; PMCID: PMC5984702.
      Citations: 9     Fields:    Translation:Humans
    209. El Beaino M, Roszik J, Livingston JA, Wang WL, Lazar AJ, Amini B, Subbiah V, Lewis V, Conley AP. Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology. Curr Oncol Rep. 2018 03 26; 20(5):37. PMID: 29582189.
      Citations: 8     Fields:    Translation:Humans
    210. Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC. Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review. Arch Pathol Lab Med. 2018 10; 142(10):1242-1253. PMID: 29504834.
      Citations: 36     Fields:    Translation:Humans
    211. Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC. Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review. J Clin Oncol. 2018 06 01; 36(16):1631-1641. PMID: 29504847.
      Citations: 265     Fields:    Translation:Humans
    212. Romano G, Chen PL, Song P, McQuade JL, Liang RJ, Liu M, Roh W, Duose DY, Carapeto FCL, Li J, Teh JLF, Aplin AE, Chen M, Zhang J, Lazar AJ, Davies MA, Futreal PA, Amaria RN, Zhang DY, Wargo JA, Kwong LN. A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling. Cancer Discov. 2018 05; 8(5):556-567. PMID: 29496665; PMCID: PMC5932238.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    213. Cooper LA, Demicco EG, Saltz JH, Powell RT, Rao A, Lazar AJ. PanCancer insights from The Cancer Genome Atlas: the pathologist's perspective. J Pathol. 2018 04; 244(5):512-524. PMID: 29288495; PMCID: PMC6240356.
      Citations: 56     Fields:    Translation:Humans
    214. Roland CL, Bednarski BK, Watson K, Torres KE, Cormier JN, Wang WL, Lazar AJ, Somaiah N, Hunt KK, Feig BW. Identification of preoperative factors associated with outcomes following surgical management of intra-abdominal recurrent or metastatic GIST following neoadjuvant tyrosine kinase inhibitor therapy. J Surg Oncol. 2018 Apr; 117(5):879-885. PMID: 29448300; PMCID: PMC5992050.
      Citations: 3     Fields:    Translation:Humans
    215. Amaria RN, Prieto PA, Tetzlaff MT, Reuben A, Andrews MC, Ross MI, Glitza IC, Cormier J, Hwu WJ, Tawbi HA, Patel SP, Lee JE, Gershenwald JE, Spencer CN, Gopalakrishnan V, Bassett R, Simpson L, Mouton R, Hudgens CW, Zhao L, Zhu H, Cooper ZA, Wani K, Lazar A, Hwu P, Diab A, Wong MK, McQuade JL, Royal R, Lucci A, Burton EM, Reddy S, Sharma P, Allison J, Futreal PA, Woodman SE, Davies MA, Wargo JA. Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial. Lancet Oncol. 2018 02; 19(2):181-193. PMID: 29361468.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    216. Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O, Akbani R, Bristow CA, Hoadley KA, Iype L, Chang MT, TCGA Research Network, Cherniack AD, Benz C, Mills GB, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC, Gershenwald JE, Schoenfield L, Lazar AJ, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE, Esmaeli B, Kandoth C, Woodman SE. Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma. Cancer Cell. 2018 01 08; 33(1):151. PMID: 29316429.
      Citations: 41     Fields:    
    217. Ali AM, Wang WL, Lazar AJ. Primary chondro-osseous melanoma (chondrosarcomatous and osteosarcomatous melanoma). J Cutan Pathol. 2018 Feb; 45(2):146-150. PMID: 29068062.
      Citations: 1     Fields:    Translation:Humans
    218. Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA, Zitvogel L. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science. 2018 01 05; 359(6371):97-103. PMID: 29097493; PMCID: PMC5827966.
      Citations: 1227     Fields:    Translation:HumansAnimals
    219. Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S, Lazar AJ, Pant S. Overview of the TREC 2017 Precision Medicine Track. Text Retr Conf. 2017 Nov; 26. PMID: 32776021; PMCID: PMC7410346.
      Citations:    
    220. Keung EZ, Tsai JW, Ali AM, Cormier JN, Bishop AJ, Guadagnolo BA, Torres KE, Somaiah N, Hunt KK, Wargo JA, Lazar AJ, Wang WL, Roland CL. Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy: Rationale for combination neoadjuvant immune checkpoint inhibition and radiotherapy. Oncoimmunology. 2018; 7(2):e1385689. PMID: 29308306; PMCID: PMC5749668.
      Citations: 19     Fields:    
    221. Panse G, Chrisinger JS, Leung CH, Ingram DR, Khan S, Wani K, Lin H, Lazar AJ, Wang WL. Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas. Histopathology. 2018 Jan; 72(2):239-247. PMID: 28796347.
      Citations: 6     Fields:    Translation:Humans
    222. Gershenwald JE, Scolyer RA, Hess KR, Sondak VK, Long GV, Ross MI, Lazar AJ, Faries MB, Kirkwood JM, McArthur GA, Haydu LE, Eggermont AMM, Flaherty KT, Balch CM, Thompson JF, for members of the American Joint Committee on Cancer Melanoma Expert Panel and the International Me. Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual. CA Cancer J Clin. 2017 Nov; 67(6):472-492. PMID: 29028110; PMCID: PMC5978683.
      Citations: 454     Fields:    Translation:Humans
    223. Nagarajan R, Bartley AN, Bridge JA, Jennings LJ, Kamel-Reid S, Kim A, Lazar AJ, Lindeman NI, Moncur J, Rai AJ, Routbort MJ, Vasalos P, Merker JD. A Window Into Clinical Next-Generation Sequencing-Based Oncology Testing Practices. Arch Pathol Lab Med. 2017 Dec; 141(12):1679-1685. PMID: 29028368.
      Citations: 7     Fields:    Translation:Humans
    224. Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S. Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial. Lancet Oncol. 2017 11; 18(11):1493-1501. PMID: 28988646; PMCID: PMC7939029.
      Citations: 359     Fields:    Translation:HumansCTClinical Trials
    225. May CD, Landers SM, Bolshakov S, Ma X, Ingram DR, Kivlin CM, Watson KL, Sannaa GAA, Bhalla AD, Wang WL, Lazar AJ, Torres KE. Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma. Cancer Biol Ther. 2017 10 03; 18(10):816-826. PMID: 29099264; PMCID: PMC5678691.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    226. Livingston JA, Barbo A, Lin H, Madewell JE, Wang WL, Lazar AJ, Tseng WW, Roland CL, Feig BW, Pollock R, Conley AP, Benjamin RS, Patel S, Somaiah N, Bugano D. Role of chemotherapy in dedifferentiated liposarcoma of the retroperitoneum: defining the benefit and challenges of the standard. Sci Rep. 2017 09 19; 7(1):11836. PMID: 28928422; PMCID: PMC5605500.
      Citations: 23     Fields:    Translation:Humans
    227. Young ED, Ingram D, Metcalf-Doetsch W, Khan D, Al Sannaa G, Le Loarer F, Lazar AJF, Slopis J, Torres KE, Lev D, Pollock RE, McCutcheon IE. Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers. J Neurosurg. 2018 09; 129(3):805-814. PMID: 28885122.
      Citations: 6     Fields:    Translation:Humans
    228. Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Babur O, Akbani R, Bristow CA, Hoadley KA, Iype L, Chang MT, TCGA Research Network, Cherniack AD, Benz C, Mills GB, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC, Gershenwald JE, Schoenfield L, Lazar AJ, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE, Esmaeli B, Woodman SE, Walter V, Penson A, Kandoth C. Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma. Cancer Cell. 2017 08 14; 32(2):204-220.e15. PMID: 28810145; PMCID: PMC5619925.
      Citations: 275     Fields:    Translation:HumansCells
    229. Reuben A, Petaccia de Macedo M, McQuade J, Joon A, Ren Z, Calderone T, Conner B, Wani K, Cooper ZA, Tawbi H, Tetzlaff MT, Padera RF, Durand JB, Lazar AJ, Wargo JA, Davies MA. Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab. Oncoimmunology. 2017; 6(12):e1361097. PMID: 29209563; PMCID: PMC5706622.
      Citations: 19     Fields:    
    230. Patel NR, Chrisinger JSA, Demicco EG, Sarabia SF, Reuther J, Kumar E, Oliveira AM, Billings SD, Roy A, Lazar AJ, Lopez-Terrada DH, Wang WL, Bov?e JVMG. USP6 activation in nodular fasciitis by promoter-swapping gene fusions. Mod Pathol. 2017 11; 30(11):1577-1588. PMID: 28752842.
      Citations: 24     Fields:    Translation:HumansCells
    231. Demicco EG, Wagner MJ, Maki RG, Gupta V, Iofin I, Lazar AJ, Wang WL. Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model. Mod Pathol. 2017 10; 30(10):1433-1442. PMID: 28731041.
      Citations: 56     Fields:    Translation:Humans
    232. Wagner MJ, Gopalakrishnan V, Ravi V, Livingston JA, Conley AP, Araujo D, Somaiah N, Zarzour MA, Ratan R, Wang WL, Patel SR, Lazar A, Ludwig JA, Benjamin RS. Vincristine, Ifosfamide, and Doxorubicin for Initial Treatment of Ewing Sarcoma in Adults. Oncologist. 2017 10; 22(10):1271-1277. PMID: 28710342; PMCID: PMC5634776.
      Citations: 11     Fields:    Translation:Humans
    233. O'Rourke A, Humphries K, Lazar A, Martin-Harris B. The pharyngeal contractile integral is a useful indicator of pharyngeal swallowing impairment. Neurogastroenterol Motil. 2017 Dec; 29(12). PMID: 28699250; PMCID: PMC5690888.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    234. Conley AP, Trinh VA, Zobniw CM, Posey K, Martinez JD, Arrieta OG, Wang WL, Lazar AJ, Somaiah N, Roszik J, Patel SR. Positive Tumor Response to Combined Checkpoint Inhibitors in a Patient With Refractory Alveolar Soft Part Sarcoma: A Case Report. J Glob Oncol. 2018 09; 4:1-6. PMID: 30241159; PMCID: PMC6180844.
      Citations: 13     Fields:    Translation:Humans
    235. Al-Zaid T, Wang WL, Somaiah N, Lazar AJ. Molecular profiling of sarcomas: new vistas for precision medicine. Virchows Arch. 2017 Aug; 471(2):243-255. PMID: 28664413.
      Citations: 2     Fields:    Translation:Humans
    236. de Graaff MA, Malu S, Guardiola I, Kruisselbrink AB, de Jong Y, Corver WE, Gelderblom H, Hwu P, Nielsen TO, Lazar AJ, Somaiah N, Bov?e JVMG. High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth. Transl Oncol. 2017 Aug; 10(4):546-554. PMID: 28654818; PMCID: PMC5487254.
      Citations: 6     
    237. Charville GW, Wang WL, Ingram DR, Roy A, Thomas D, Patel RM, Hornick JL, van de Rijn M, Lazar AJ. EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma. Mod Pathol. 2017 09; 30(9):1312-1320. PMID: 28643791.
      Citations: 22     Fields:    Translation:HumansCells
    238. Dodd RD, Lee CL, Overton T, Huang W, Eward WC, Luo L, Ma Y, Ingram DR, Torres KE, Cardona DM, Lazar AJ, Kirsch DG. NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response. Cancer Res. 2017 08 15; 77(16):4486-4497. PMID: 28646022; PMCID: PMC5839126.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    239. Leon-Castillo A, Chrisinger JSA, Panse G, Samdani RT, Ingram DR, Ravi V, Prieto VG, Wang WL, Lazar AJ. Index report of cutaneous angiosarcomas with strong positivity for tyrosinase mimicking melanoma with further evaluation of melanocytic markers in a large angiosarcoma series. J Cutan Pathol. 2017 Aug; 44(8):692-697. PMID: 28556023.
      Citations:    Fields:    Translation:HumansCells
    240. Roszik J, Wang WL, Livingston JA, Roland CL, Ravi V, Yee C, Hwu P, Futreal A, Lazar AJ, Patel SR, Conley AP. Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes. Clin Sarcoma Res. 2017; 7:11. PMID: 28630682; PMCID: PMC5471883.
      Citations: 19     
    241. Gopalakrishnan V, Amini B, Wagner MJ, Nowell EN, Lazar AJ, Lin PP, Benjamin RS, Araujo DM. Synovial Sarcoma of the Head and Neck: A Single Institution Review. Sarcoma. 2017; 2017:2016752. PMID: 28655993; PMCID: PMC5474548.
      Citations: 5     
    242. Sarkar S, Bristow CA, Dey P, Rai K, Perets R, Ramirez-Cardenas A, Malasi S, Huang-Hobbs E, Haemmerle M, Wu SY, McGuire M, Protopopov A, Jiang S, Liu JF, Hirsch MS, Chang Q, Lazar AJ, Sood AK, Drapkin R, DePinho R, Draetta G, Chin L. PRKCI promotes immune suppression in ovarian cancer. Genes Dev. 2017 06 01; 31(11):1109-1121. PMID: 28698296; PMCID: PMC5538434.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    243. Miettinen MM, Antonescu CR, Fletcher CDM, Kim A, Lazar AJ, Quezado MM, Reilly KM, Stemmer-Rachamimov A, Stewart DR, Viskochil D, Widemann B, Perry A. Histopathologic evaluation of atypical neurofibromatous tumors and their transformation into malignant peripheral nerve sheath tumor in patients with neurofibromatosis 1-a consensus overview. Hum Pathol. 2017 09; 67:1-10. PMID: 28551330; PMCID: PMC5628119.
      Citations: 86     Fields:    Translation:HumansCells
    244. Semenova G, Stepanova DS, Dubyk C, Handorf E, Deyev SM, Lazar AJ, Chernoff J. Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis. Oncogene. 2017 09 21; 36(38):5421-5431. PMID: 28534510; PMCID: PMC5608634.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    245. Qin Y, Petaccia de Macedo M, Reuben A, Haymaker C, Bernatchez C, Spencer CN, Gopalakrishnan V, Reddy S, Cooper ZA, Fulbright OJ, Ramachandran R, Wahl A, Flores E, Thorsen ST, Tavera RJ, Conrad C, Williams MD, Tetzlaff MT, Wang WL, Gombos DS, Esmaeli B, Amaria RN, Hwu P, Wargo JA, Lazar AJ, Patel SP, Forget MA. Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study. Oncoimmunology. 2017; 6(6):e1321187. PMID: 28680759; PMCID: PMC5486182.
      Citations: 21     Fields:    
    246. El Beaino M, Araujo DM, Lazar AJ, Lin PP. Synovial Sarcoma: Advances in Diagnosis and Treatment Identification of New Biologic Targets to Improve Multimodal Therapy. Ann Surg Oncol. 2017 Aug; 24(8):2145-2154. PMID: 28397189.
      Citations: 28     Fields:    Translation:Humans
    247. Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen PL, Beird HC, Garber HR, Roh W, Wani K, Chen E, Haymaker C, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS, Nezi L, Cogdill AP, Bernatchez C, Roszik J, Hwu P, Woodman SE, Chin L, Tawbi H, Davies MA, Gershenwald JE, Amaria RN, Glitza IC, Diab A, Patel SP, Hu J, Lee JE, Grimm EA, Tetzlaff MT, Lazar AJ, Wistuba II, Clise-Dwyer K, Carter BW, Zhang J, Futreal PA, Sharma P, Allison JP, Cooper ZA, Wargo JA, Forget MA. Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma. NPJ Genom Med. 2017; 2. PMID: 28819565; PMCID: PMC5557036.
      Citations: 64     
    248. Esmaeli B, Ellerhorst JA, Lyons GR, Wang WL, Macedo MP, Lazar AJ, Grimm EA, Chattopadhyay C, Oba J, Milton DR. Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression. Melanoma Res. 2017 04; 27(2):126-133. PMID: 28118269.
      Citations: 2     Fields:    Translation:Humans
    249. Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J, Tetzlaff MT, Davies MA, Gershenwald JE, Tawbi H, Lazar AJ, Hwu P, Hwu WJ, Diab A, Glitza IC, Patel SP, Woodman SE, Amaria RN, Prieto VG, Hu J, Sharma P, Allison JP, Chin L, Zhang J, Wargo JA, Futreal PA. Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance. Sci Transl Med. 2017 03 01; 9(379). PMID: 28251903; PMCID: PMC5819607.
      Citations: 323     Fields:    Translation:HumansCells
    250. Wang WL, Lazar AJ. Undifferentiated "round" cell ("Ewing-like") sarcoma: not always so-round nor Ewing-like. Virchows Arch. 2017 04; 470(4):371-372. PMID: 28191614.
      Citations: 1     Fields:    Translation:Humans
    251. Panse G, Leung CH, Ingram DR, Wani K, Torres KE, Lin H, Lazar AJ, Wang WL. The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours. Histopathology. 2017 May; 70(6):946-953. PMID: 27992966.
      Citations: 4     Fields:    Translation:HumansCells
    252. Kim DW, Haydu LE, Joon AY, Bassett RL, Siroy AE, Tetzlaff MT, Routbort MJ, Amaria RN, Wargo JA, McQuade JL, Kemnade J, Hwu P, Woodman SE, Roszik J, Kim KB, Gershenwald JE, Lazar AJ, Davies MA. Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients. Cancer. 2017 04 15; 123(8):1372-1381. PMID: 27911979; PMCID: PMC5384865.
      Citations: 18     Fields:    Translation:Humans
    253. Kumar E, Patel NR, Demicco EG, Bovee JV, Olivera AM, Lopez-Terrada DH, Billings SD, Lazar AJ, Wang WL. Cutaneous nodular fasciitis with genetic analysis: a case series. J Cutan Pathol. 2016 Dec; 43(12):1143-1149. PMID: 27686647.
      Citations: 5     Fields:    Translation:Humans
    254. Barrott JJ, Kafchinski LA, Jin H, Potter JW, Kannan SD, Kennedy R, Mosbruger T, Wang WL, Tsai JW, Araujo DM, Liu T, Capecchi MR, Lazar AJ, Jones KB. Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation. J Exp Med. 2016 12 12; 213(13):2989-3005. PMID: 27956588; PMCID: PMC5154942.
      Citations: 16     Fields:    Translation:AnimalsCells
    255. Roszik J, Haydu LE, Hess KR, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC, Baladandayuthapani V, Tetzlaff MT, Wargo JA, Chen K, Haymaker CL, Chen JQ, Meric-Bernstam F, Eterovic AK, Shaw KR, Mills GB, Gershenwald JE, Radvanyi LG, Hwu P, Futreal PA, Gibbons DL, Lazar AJ, Bernatchez C, Davies MA, Woodman SE, Forget MA. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Med. 2016 10 25; 14(1):168. PMID: 27776519; PMCID: PMC5078889.
      Citations: 64     Fields:    Translation:HumansCells
    256. Varma S, Dumont SN, Zambrano E, Trent JC, Lazar AJ, van de Rijn M, Charville GW, Forg? E. PAX7 Expression in Rhabdomyosarcoma, Related Soft Tissue Tumors, and Small Round Blue Cell Neoplasms. Am J Surg Pathol. 2016 10; 40(10):1305-15. PMID: 27526298.
      Citations: 9     Fields:    Translation:Humans
    257. Bird JE, Morse LJ, Feng L, Wang WL, Lin PP, Moon BS, Lazar AJ, Satcher RL, Madewell JE, Lewis VO. Non-Radiographic Risk Factors Differentiating Atypical Lipomatous Tumors from Lipomas. Front Oncol. 2016; 6:197. PMID: 27713864; PMCID: PMC5031604.
      Citations: 6     
    258. Al Sannaa G, Watson KL, Olar A, Wang WL, Fuller GN, McCutcheon I, Torres KE, Lazar AJ. Sarcoma Brain Metastases: 28?Years of Experience at a Single Institution. Ann Surg Oncol. 2016 12; 23(Suppl 5):962-967. PMID: 27646022.
      Citations: 3     Fields:    Translation:Humans
    259. Cleven AH, Al Sannaa GA, Briaire-de Bruijn I, Ingram DR, van de Rijn M, Rubin BP, de Vries MW, Watson KL, Torres KE, Wang WL, van Duinen SG, Hogendoorn PC, Lazar AJ, Bov?e JV. Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival. Mod Pathol. 2016 09; 29(9):1113. PMID: 27573709.
      Citations: 13     Fields:    
    260. Lamhamedi-Cherradi SE, Menegaz BA, Ramamoorthy V, Vishwamitra D, Wang Y, Maywald RL, Buford AS, Fokt I, Skora S, Wang J, Naing A, Lazar AJ, Rohren EM, Daw NC, Subbiah V, Benjamin RS, Ratan R, Priebe W, Mikos AG, Amin HM, Ludwig JA. IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma. J Natl Cancer Inst. 2016 12; 108(12). PMID: 27576731; PMCID: PMC5241894.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    261. Chen G, McQuade JL, Panka DJ, Hudgens CW, Amin-Mansour A, Mu XJ, Bahl S, Wani KM, Reuben A, Creasy CA, Jiang H, Cooper ZA, Roszik J, Bassett RL, Joon AY, Simpson LM, Mouton RD, Glitza IC, Patel SP, Hwu WJ, Amaria RN, Diab A, Hwu P, Lazar AJ, Wargo JA, Garraway LA, Tetzlaff MT, Sullivan RJ, Kim KB, Davies MA, Jan?-Valbuena J. Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial. JAMA Oncol. 2016 Aug 01; 2(8):1056-64. PMID: 27124486; PMCID: PMC4982774.
      Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
    262. Roland CL, Wang WL, Lazar AJ, Torres KE. Myxofibrosarcoma. Surg Oncol Clin N Am. 2016 10; 25(4):775-88. PMID: 27591498.
      Citations: 22     Fields:    Translation:Humans
    263. Chen PL, Roh W, Reuben A, Cooper ZA, Spencer CN, Prieto PA, Miller JP, Bassett RL, Gopalakrishnan V, Wani K, De Macedo MP, Austin-Breneman JL, Jiang H, Chang Q, Reddy SM, Chen WS, Tetzlaff MT, Broaddus RJ, Davies MA, Gershenwald JE, Haydu L, Lazar AJ, Patel SP, Hwu P, Hwu WJ, Diab A, Glitza IC, Woodman SE, Vence LM, Wistuba II, Amaria RN, Kwong LN, Prieto V, Davis RE, Ma W, Overwijk WW, Sharpe AH, Hu J, Futreal PA, Blando J, Sharma P, Allison JP, Chin L, Wargo JA. Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade. Cancer Discov. 2016 08; 6(8):827-37. PMID: 27301722; PMCID: PMC5082984.
      Citations: 385     Fields:    Translation:HumansCells
    264. de Graaff MA, Yu JS, Beird HC, Ingram DR, Nguyen T, Juehui Liu J, Bolshakov S, Torres KE, Lev D, Nielsen TO, Lazar AJ, Somaiah N, Szuhai K, ?man P, Bov?e JV. Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation. Lab Invest. 2016 08; 96(8):885-94. PMID: 27270875; PMCID: PMC4965313.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    265. Loghavi S, Routbort MJ, Patel KP, Luthra R, Wang WL, Broaddus RR, Davies MA, Lazar AJ. How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments? J Natl Compr Canc Netw. 2016 06; 14(6):787-92. PMID: 27283170.
      Citations:    Fields:    Translation:Humans
    266. El Beaino M, Araujo DM, Gopalakrishnan V, Lazar AJ, Lin PP. Prognosis of T1 synovial sarcoma depends upon surgery by oncologic surgeons. J Surg Oncol. 2016 Sep; 114(4):490-4. PMID: 27220538.
      Citations: 4     Fields:    Translation:Humans
    267. Roland CL, Boland GM, Demicco EG, Lusby K, Ingram D, May CD, Kivlin CM, Watson K, Al Sannaa GA, Wang WL, Ravi V, Pollock RE, Lev D, Cormier JN, Hunt KK, Feig BW, Lazar AJ, Torres KE. Clinical Observations and Molecular Variables of Primary Vascular Leiomyosarcoma. JAMA Surg. 2016 Apr; 151(4):347-54. PMID: 26629783; PMCID: PMC4941943.
      Citations: 9     Fields:    Translation:Humans
    268. Cleven AH, Sannaa GA, Briaire-de Bruijn I, Ingram DR, van de Rijn M, Rubin BP, de Vries MW, Watson KL, Torres KE, Wang WL, van Duinen SG, Hogendoorn PC, Lazar AJ, Bov?e JV. Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival. Mod Pathol. 2016 06; 29(6):582-90. PMID: 26990975; PMCID: PMC4948583.
      Citations: 63     Fields:    Translation:HumansCells
    269. Roland CL, May CD, Watson KL, Al Sannaa GA, Dineen SP, Feig R, Landers S, Ingram DR, Wang WL, Guadagnolo BA, Feig B, Hunt KK, Cormier JN, Lazar AJ, Torres KE. Analysis of Clinical and Molecular Factors Impacting Oncologic Outcomes in Undifferentiated Pleomorphic Sarcoma. Ann Surg Oncol. 2016 07; 23(7):2220-8. PMID: 26847678; PMCID: PMC4937623.
      Citations: 15     Fields:    Translation:Humans
    270. Messiou C, Bonvalot S, Gronchi A, Vanel D, Meyer M, Robinson P, Morosi C, Bloem JL, Terrier PH, Lazar A, Winfield JM, Boulet B, Haas RL, Le P?choux C, Wardelman E, Bov?e J. Evaluation of response after pre-operative radiotherapy in soft tissue sarcomas; the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) and Imaging Group recommendations for radiological examination and reporting with an emphasis on magnetic resonance imaging. Eur J Cancer. 2016 Mar; 56:37-44. PMID: 26802529.
      Citations: 13     Fields:    Translation:Humans
    271. Roszik J, Wu CJ, Siroy AE, Lazar AJ, Davies MA, Woodman SE, Kwong LN. Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression. Sci Rep. 2016 Jan 20; 6:19649. PMID: 26787600; PMCID: PMC4726397.
      Citations: 5     Fields:    Translation:Humans
    272. Kattan MW, Hess KR, Amin MB, Lu Y, Moons KG, Gershenwald JE, Gimotty PA, Guinney JH, Halabi S, Lazar AJ, Mahar AL, Patel T, Sargent DJ, Weiser MR, Compton C, members of the AJCC Precision Medicine Core. American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine. CA Cancer J Clin. 2016 09; 66(5):370-4. PMID: 26784705; PMCID: PMC4955656.
      Citations: 90     Fields:    Translation:Humans
    273. Maher OM, Khatua S, Mukherjee D, Olar A, Lazar A, Luthra R, Liu D, Wu J, Ketonen L, Zaky W. Primary intracranial soft tissue sarcomas in children, adolescents, and young adults: single institution experience and review of the literature. J Neurooncol. 2016 Mar; 127(1):155-63. PMID: 26718692; PMCID: PMC4876035.
      Citations: 1     Fields:    Translation:Humans
    274. Haas RL, Terrier P, Lazar A, Messiou C, LePechoux C, Collin F, Fisher C, Mechtersheimer G, DeiTos AP, Stacchiotti S, Jones RL, Gronchi A, Bonvalot S, Wardelmann E, Bov?e JV, Hartmann W. Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting. Eur J Cancer. 2016 Jan; 53:84-95. PMID: 26700077.
      Citations: 20     Fields:    Translation:Humans
    275. Kivlin CM, Watson KL, Al Sannaa GA, Belousov R, Ingram DR, Huang KL, May CD, Bolshakov S, Landers SM, Kalam AA, Slopis JM, McCutcheon IE, Pollock RE, Lev D, Lazar AJ, Torres KE. Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor. Cancer Biol Ther. 2016; 17(2):129-38. PMID: 26650448; PMCID: PMC4847988.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    276. Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL, Bosenberg MW, Woodman SE, Overwijk WW, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P, Liz?e G. Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy. Cancer Discov. 2016 Feb; 6(2):202-16. PMID: 26645196; PMCID: PMC4744499.
      Citations: 581     Fields:    Translation:HumansAnimalsCells
    277. Cleton-Jansen AM, Wijers-Koster P, Coffin CM, Lazar AJ, Nout RA, Rubin BP, Gelderblom H, Verschoor AJ, Bov?e JV. Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor. Am J Surg Pathol. 2015 Dec; 39(12):1701-7. PMID: 26414222.
      Citations: 1     Fields:    Translation:Humans
    278. Kamali F, Wang WL, Guadagnolo BA, Fox PS, Lewis VO, Lazar AJ, Conley AP, Ravi V, Toliyat M, Ladha HS, Hobbs BP, Amini B. MRI may be used as a prognostic indicator in patients with extra-abdominal desmoid tumours. Br J Radiol. 2016; 89(1058):20150308. PMID: 26577289; PMCID: PMC4985189.
      Citations: 6     Fields:    Translation:Humans
    279. May CD, Garnett J, Ma X, Landers SM, Ingram DR, Demicco EG, Al Sannaa GA, Vu T, Han L, Zhang Y, Kivlin CM, Bolshakov S, Kalam AA, Liu J, Zhou F, Broccoli D, Wang WL, Lazar AJ, Pollock RE, Lev D, Torres KE. AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas. BMC Cancer. 2015 Nov 14; 15:901. PMID: 26573603; PMCID: PMC4647521.
      Citations: 11     Fields:    Translation:HumansCells
    280. Chinyengetere F, Sekula DJ, Lu Y, Giustini AJ, Sanglikar A, Kawakami M, Ma T, Burkett SS, Eisenberg BL, Wells WA, Hoopes PJ, Demicco EG, Lazar AJ, Torres KE, Memoli V, Freemantle SJ, Dmitrovsky E. Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas. BMC Cancer. 2015 Nov 10; 15:886. PMID: 26555296; PMCID: PMC4640382.
      Citations: 8     Fields:    Translation:HumansAnimals
    281. Roy-Chowdhuri S, de Melo Gagliato D, Routbort MJ, Patel KP, Singh RR, Broaddus R, Lazar AJ, Sahin A, Alvarez RH, Moulder S, Wheler JJ, Janku F, Gonzalez-Angulo AM, Chavez-MacGregor M, Valero V, Ueno NT, Mills G, Mendelsohn J, Yao H, Aldape K, Luthra R, Meric-Bernstam F. Multigene clinical mutational profiling of breast carcinoma using next-generation sequencing. Am J Clin Pathol. 2015 Nov; 144(5):713-21. PMID: 26486734.
      Citations: 13     Fields:    Translation:Humans
    282. Jamshidi F, Bashashati A, Shumansky K, Dickson B, Gokgoz N, Wunder JS, Andrulis IL, Lazar AJ, Shah SP, Huntsman DG, Nielsen TO. The genomic landscape of epithelioid sarcoma cell lines and tumours. J Pathol. 2016 Jan; 238(1):63-73. PMID: 26365879.
      Citations: 21     Fields:    Translation:HumansCells
    283. Bill KL, Garnett J, Meaux I, Ma X, Creighton CJ, Bolshakov S, Barriere C, Debussche L, Lazar AJ, Prudner BC, Casadei L, Braggio D, Lopez G, Zewdu A, Bid H, Lev D, Pollock RE. SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma. Clin Cancer Res. 2016 Mar 01; 22(5):1150-60. PMID: 26475335; PMCID: PMC4775372.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    284. Rai K, Akdemir KC, Kwong LN, Fiziev P, Wu CJ, Keung EZ, Sharma S, Samant NS, Williams M, Axelrad JB, Shah A, Yang D, Grimm EA, Barton MC, Milton DR, Heffernan TP, Horner JW, Ekmekcioglu S, Lazar AJ, Ernst J, Chin L. Dual Roles of RNF2 in Melanoma Progression. Cancer Discov. 2015 Dec; 5(12):1314-27. PMID: 26450788; PMCID: PMC4670809.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    285. Shang H, Braggio D, Lee YJ, Al Sannaa GA, Creighton CJ, Bolshakov S, Lazar AJ, Lev D, Pollock RE. Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors. Cancer. 2015 Nov 15; 121(22):4088-96. PMID: 26349011; PMCID: PMC4635059.
      Citations: 18     Fields:    Translation:HumansCells
    286. Sholl LM, Andea A, Bridge JA, Cheng L, Davies MA, Ehteshami M, Gangadhar TC, Kamel-Reid S, Lazar A, Raparia K, Siroy A, Watson KL, Members of Cancer Biomarker Reporting Committee, College of American Pathologists. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Melanoma. Arch Pathol Lab Med. 2016 Apr; 140(4):355-7. PMID: 26340412.
      Citations: 3     Fields:    Translation:Humans
    287. Jharap B, Sandborn WJ, Reinisch W, D'Haens G, Robinson AM, Wang W, Huang B, Lazar A, Thakkar RB, Colombel JF. Randomised clinical study: discrepancies between patient-reported outcomes and endoscopic appearance in moderate to severe ulcerative colitis. Aliment Pharmacol Ther. 2015 Nov; 42(9):1082-92. PMID: 26381802; PMCID: PMC5049645.
      Citations: 28     Fields:    Translation:HumansCTClinical Trials
    288. Keung EZ, Akdemir KC, Al Sannaa GA, Garnett J, Lev D, Torres KE, Lazar AJ, Rai K, Chin L. Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma. J Clin Invest. 2015 Aug 03; 125(8):2965-78. PMID: 26193637; PMCID: PMC4563740.
      Citations: 15     Fields:    Translation:HumansCells
    289. Tseng WW, Zhou S, To CA, Thall PF, Lazar AJ, Pollock RE, Lin PP, Cormier JN, Lewis VO, Feig BW, Hunt KK, Ballo MT, Patel S, Pisters PW. Phase 1 adaptive dose-finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high-risk extremity and trunk soft tissue sarcoma. Cancer. 2015 Oct 15; 121(20):3659-67. PMID: 26177983; PMCID: PMC4777348.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    290. Bill KL, Garnett J, Ma X, May CD, Bolshakov S, Lazar AJ, Lev DC, Pollock RE. The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma. Lab Invest. 2015 Aug; 95(8):951-61. PMID: 26006023; PMCID: PMC4520775.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    291. Torres-Cabala C, Curry JL, Ivan D, McLemore M, Tetzlaff M, Zembowicz A, Prieto VG, Lazar AJ, Wang WL. Metastatic atypical fibroxanthoma: a series of 11 cases including with minimal and no subcutaneous involvement. Am J Dermatopathol. 2015 Jun; 37(6):455-61. PMID: 25590287.
      Citations: 4     Fields:    Translation:Humans
    292. Patel NR, Salim AA, Sayeed H, Sarabia SF, Hollingsworth F, Warren M, Jakacky J, Tanas M, Oliveira AM, Rubin BP, Lazar AJ, Wang WL, L?pez-Terrada D. Molecular characterization of epithelioid haemangioendotheliomas identifies novel WWTR1-CAMTA1 fusion variants. Histopathology. 2015 Nov; 67(5):699-708. PMID: 25817592.
      Citations: 15     Fields:    Translation:Humans
    293. Tetzlaff MT, Pattanaprichakul P, Wargo J, Fox PS, Patel KP, Estrella JS, Broaddus RR, Williams MD, Davies MA, Routbort MJ, Lazar AJ, Woodman SE, Hwu WJ, Gershenwald JE, Prieto VG, Torres-Cabala CA, Curry JL. Utility of BRAF V600E Immunohistochemistry Expression Pattern as a Surrogate of BRAF Mutation Status in 154 Patients with Advanced Melanoma. Hum Pathol. 2015 Aug; 46(8):1101-10. PMID: 26058727; PMCID: PMC4515190.
      Citations: 13     Fields:    Translation:Humans
    294. Demicco EG, Harms PW, Patel RM, Smith SC, Ingram D, Torres K, Carskadon SL, Camelo-Piragua S, McHugh JB, Siddiqui J, Palanisamy N, Lucas DR, Lazar AJ, Wang WL. Extensive survey of STAT6 expression in a large series of mesenchymal tumors. Am J Clin Pathol. 2015 May; 143(5):672-82. PMID: 25873501; PMCID: PMC4505928.
      Citations: 53     Fields:    Translation:HumansCells
    295. Demicco EG, Wani K, Fox PS, Bassett RL, Young ED, Lev D, Aldape KD, Lazar AJ, Wang WL. Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations. Hum Pathol. 2015 Jul; 46(7):1015-26. PMID: 25976141.
      Citations: 10     Fields:    Translation:HumansCells
    296. Stockman DL, Curry JL, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L, Patel KP, Luthra R, Davies MA, Wargo JA, Routbort MA, Broaddus RR, Prieto VG, Lazar AJ, Tetzlaff MT. Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations. J Cutan Pathol. 2015 May; 42(5):308-17. PMID: 25754356.
      Citations: 6     Fields:    Translation:HumansCells
    297. Zhang P, Yang X, Ma X, Ingram DR, Lazar AJ, Torres KE, Pollock RE. Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway. Mol Cancer. 2015 Mar 07; 14:55. PMID: 25890085; PMCID: PMC4357176.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    298. Dineen SP, Roland CL, Feig R, May C, Zhou S, Demicco E, Sannaa GA, Ingram D, Wang WL, Ravi V, Guadagnolo A, Lev D, Pollock RE, Hunt K, Cormier J, Lazar A, Feig B, Torres KE. Radiation-Associated Undifferentiated Pleomorphic Sarcoma is Associated with Worse Clinical Outcomes than Sporadic Lesions. Ann Surg Oncol. 2015 Nov; 22(12):3913-20. PMID: 25743327; PMCID: PMC4561200.
      Citations: 20     Fields:    Translation:Humans
    299. Hameed M, Corless C, George S, Hornick JL, Kakar S, Lazar AJ, Tang L, Members of the Cancer Biomarker Reporting Committee, College of American Pathologists. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Gastrointestinal Stromal Tumors. Arch Pathol Lab Med. 2015 Oct; 139(10):1271-5. PMID: 25729899.
      Citations:    Fields:    Translation:Humans
    300. Goswami RS, Patel KP, Singh RR, Meric-Bernstam F, Kopetz ES, Subbiah V, Alvarez RH, Davies MA, Jabbar KJ, Roy-Chowdhuri S, Lazar AJ, Medeiros LJ, Broaddus RR, Luthra R, Routbort MJ. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clin Cancer Res. 2015 Jun 01; 21(11):2644-51. PMID: 25695693; PMCID: PMC5015593.
      Citations: 41     Fields:    Translation:Humans
    301. Romeo S, Rossi S, Canal F, Sbaraglia M, Laurino L, Mazzoleni G, Montesco MC, Valori L, Campo Dell'Orto M, Gianatti A, Lazar AJ, Dei Tos AP, Acosta Mar?n M. Primary Synovial Sarcoma (SS) of the digestive system: a molecular and clinicopathological study of fifteen cases. Clin Sarcoma Res. 2015; 5:7. PMID: 25699170; PMCID: PMC4333262.
      Citations: 15     
    302. Demicco EG, Boland GM, Brewer Savannah KJ, Lusby K, Young ED, Ingram D, Watson KL, Bailey M, Guo X, Hornick JL, van de Rijn M, Wang WL, Torres KE, Lev D, Lazar AJ. Progressive loss of myogenic differentiation in leiomyosarcoma has prognostic value. Histopathology. 2015 Apr; 66(5):627-38. PMID: 24889065; PMCID: PMC4248015.
      Citations: 12     Fields:    Translation:Humans
    303. Zhao S, Kurenbekova L, Gao Y, Roos A, Creighton CJ, Rao P, Hicks J, Man TK, Lau C, Brown AM, Jones SN, Lazar AJ, Ingram D, Lev D, Donehower LA, Yustein JT. NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma. Oncogene. 2015 Sep 24; 34(39):5069-79. PMID: 25579177; PMCID: PMC4802362.
      Citations: 57     Fields:    Translation:AnimalsCells
    304. Gong L, Govan JM, Evans EB, Dai H, Wang E, Lee SW, Lin HK, Lazar AJ, Mills GB, Lin SY. Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure. Cell Cycle. 2015; 14(14):2323-32. PMID: 25946202; PMCID: PMC4614552.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    305. Zutter MM, Bloom KJ, Cheng L, Hagemann IS, Kaufman JH, Krasinskas AM, Lazar AJ, Leonard DG, Lindeman NI, Moyer AM, Nikiforova MN, Nowak JA, Pfeifer JD, Sepulveda AR, Willis JE, Yohe SL. The Cancer Genomics Resource List 2014. Arch Pathol Lab Med. 2015 Aug; 139(8):989-1008. PMID: 25436904.
      Citations: 9     Fields:    Translation:Humans
    306. Endo M, de Graaff MA, Ingram DR, Lim S, Lev DC, Briaire-de Bruijn IH, Somaiah N, Lazar AJ, Nielsen TO, Bov?e JV. NY-ESO-1 (CTAG1B) expression in mesenchymal tumors. Mod Pathol. 2015 Apr; 28(4):587-95. PMID: 25412843.
      Citations: 36     Fields:    Translation:Humans
    307. Peters TL, Kumar V, Polikepahad S, Lin FY, Sarabia SF, Liang Y, Wang WL, Lazar AJ, Doddapaneni H, Chao H, Muzny DM, Wheeler DA, Okcu MF, Plon SE, Hicks MJ, Parsons DW, Roy A, L?pez-Terrada D. BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children. Mod Pathol. 2015 Apr; 28(4):575-86. PMID: 25360585; PMCID: PMC4385430.
      Citations: 37     Fields:    Translation:Humans
    308. Ingram DR, Dillon LM, Lev DC, Lazar A, Demicco EG, Eisenberg BL, Miller TW. Estrogen receptor alpha and androgen receptor are commonly expressed in well-differentiated liposarcoma. BMC Clin Pathol. 2014; 14:42. PMID: 25349530; PMCID: PMC4209467.
      Citations: 4     
    309. Hughes DP, Kummar S, Lazar AJ. New, tolerable ?-secretase inhibitor takes desmoid down a notch. Clin Cancer Res. 2015 Jan 01; 21(1):7-9. PMID: 25336699; PMCID: PMC4306586.
      Citations: 11     Fields:    Translation:Humans
    310. Hwang JA, Yang HM, Hong DP, Joo SY, Choi YL, Park JH, Lazar AJ, Pollock RE, Lev D, Kim SJ. Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma. Oncotarget. 2014 Oct 15; 5(19):9065-78. PMID: 25238053; PMCID: PMC4253419.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    311. Bucheit AD, Chen G, Siroy A, Tetzlaff M, Broaddus R, Milton D, Fox P, Bassett R, Hwu P, Gershenwald JE, Lazar AJ, Davies MA. Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations. Clin Cancer Res. 2014 Nov 01; 20(21):5527-36. PMID: 25165098; PMCID: PMC4216767.
      Citations: 66     Fields:    Translation:Humans
    312. Siroy AE, Boland GM, Roszik J, Frankian S, Malke J, Haydu L, Prieto VG, Tetzlaff M, Ivan D, Wang WL, Torres-Cabala C, Curry J, Roy-Chowdhuri S, Broaddus R, Rashid A, Stewart J, Gershenwald JE, Amaria RN, Patel SP, Papadopoulos NE, Bedikian A, Hwu WJ, Hwu P, Diab A, Woodman SE, Aldape KD, Luthra R, Patel KP, Shaw KR, Mills GB, Mendelsohn J, Meric-Bernstam F, Kim KB, Routbort MJ, Lazar AJ, Davies MA, Milton DR. Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma. J Invest Dermatol. 2015 Feb; 135(2):508-515. PMID: 25148578; PMCID: PMC4289407.
      Citations: 56     Fields:    Translation:Humans
    313. Wolf D, D'Haens G, Sandborn WJ, Colombel JF, Van Assche G, Robinson AM, Lazar A, Zhou Q, Petersson J, Thakkar RB. Escalation to weekly dosing recaptures response in adalimumab-treated patients with moderately to severely active ulcerative colitis. Aliment Pharmacol Ther. 2014 Sep; 40(5):486-97. PMID: 25041859.
      Citations: 19     Fields:    Translation:Humans
    314. Gontarz M, Wyszynska-Pawelec G, Zapala J, Czopek J, Lazar A, Tomaszewska R. Proliferative index activity in oral squamous cell carcinoma: indication for postoperative radiotherapy? Int J Oral Maxillofac Surg. 2014 Oct; 43(10):1189-94. PMID: 24814691.
      Citations: 1     Fields:    Translation:Humans
    315. Chen G, Chakravarti N, Aardalen K, Lazar AJ, Tetzlaff MT, Wubbenhorst B, Kim SB, Kopetz S, Ledoux AA, Gopal YN, Pereira CG, Deng W, Lee JS, Nathanson KL, Aldape KD, Prieto VG, Stuart D, Davies MA. Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target. Clin Cancer Res. 2014 Nov 01; 20(21):5537-46. PMID: 24803579; PMCID: PMC4216765.
      Citations: 70     Fields:    Translation:HumansCells
    316. Tseng WW, Madewell JE, Wei W, Somaiah N, Lazar AJ, Ghadimi MP, Hoffman A, Pisters PW, Lev DC, Pollock RE. Locoregional disease patterns in well-differentiated and dedifferentiated retroperitoneal liposarcoma: implications for the extent of resection? Ann Surg Oncol. 2014 Jul; 21(7):2136-43. PMID: 24705628.
      Citations: 33     Fields:    Translation:Humans
    317. Shaker M, Pascarelli KM, Plantinga MJ, Love MA, Lazar AJ, Ingram DR, von Mehren M, Lev D, Kipling D, Broccoli D. Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas. Biomark Cancer. 2014; 6:1-10. PMID: 24741338; PMCID: PMC3981480.
      Citations: 1     
    318. Bednarski BK, Araujo DM, Yi M, Torres KE, Lazar A, Trent JC, Cormier JN, Pisters PW, Lev DC, Pollock RE, Feig BW, Hunt KK. Analysis of prognostic factors impacting oncologic outcomes after neoadjuvant tyrosine kinase inhibitor therapy for gastrointestinal stromal tumors. Ann Surg Oncol. 2014 Aug; 21(8):2499-505. PMID: 24639192; PMCID: PMC4524653.
      Citations: 13     Fields:    Translation:Humans
    319. Abadin SS, Ayala-Ramirez M, Jimenez C, Dickson PV, Liang Y, Lazar AJ, Hornick JL, Cotton M, Sui D, Rich T, Lee JE, Grubbs E, Perrier ND. Impact of surgical resection for subdiaphragmatic paragangliomas. World J Surg. 2014 Mar; 38(3):733-41. PMID: 24390286.
      Citations: 1     Fields:    Translation:Humans
    320. Zhang P, Garnett J, Creighton CJ, Al Sannaa GA, Igram DR, Lazar A, Liu X, Liu C, Pollock RE. EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis. J Pathol. 2014 Feb; 232(3):308-18. PMID: 24132643; PMCID: PMC4166508.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    321. Wang S, Liu CH, Zakharov VP, Lazar AJ, Pollock RE, Larin KV. Three-dimensional computational analysis of optical coherence tomography images for the detection of soft tissue sarcomas. J Biomed Opt. 2014 Feb; 19(2):21102. PMID: 23807552.
      Citations: 14     Fields:    Translation:Humans
    322. Al-Zaid T, Somaiah N, Lazar AJ. Targeted therapies for sarcomas: new roles for the pathologist. Histopathology. 2014 Jan; 64(1):119-33. PMID: 24117526.
      Citations: 4     Fields:    Translation:Humans
    323. Yang J, Du X, Wang G, Sun Y, Chen K, Zhu X, Lazar AJ, Hunt KK, Pollock RE, Zhang W. Mesenchymal to epithelial transition in sarcomas. Eur J Cancer. 2014 Feb; 50(3):593-601. PMID: 24291235.
      Citations: 28     Fields:    Translation:HumansAnimals
    324. Chaudhry IH, Ramdial P, Lazar AJ, McMenamin ME, Kazakov D, Brenn T, Calonje E, Ramakrishnan R. Primary cutaneous adenoid cystic carcinoma: a clinicopathologic and immunohistochemical study of 27 cases. Am J Surg Pathol. 2013 Oct; 37(10):1603-11. PMID: 24025525.
      Citations: 19     Fields:    Translation:Humans
    325. Stockman DL, Hornick JL, Deavers MT, Lev DC, Lazar AJ, Wang WL. ERG and FLI1 protein expression in epithelioid sarcoma. Mod Pathol. 2014 Apr; 27(4):496-501. PMID: 24072183.
      Citations: 12     Fields:    Translation:HumansCells
    326. Bowles DW, Ma WW, Senzer N, Brahmer JR, Adjei AA, Davies M, Lazar AJ, Vo A, Peterson S, Walker L, Hausman D, Rudin CM, Jimeno A. A multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours. Br J Cancer. 2013 Sep 03; 109(5):1085-92. PMID: 23942080; PMCID: PMC3778312.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    327. Bucheit AD, Syklawer E, Jakob JA, Bassett RL, Curry JL, Gershenwald JE, Kim KB, Hwu P, Lazar AJ, Davies MA. Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma. Cancer. 2013 Nov 01; 119(21):3821-9. PMID: 23922205.
      Citations: 40     Fields:    Translation:Humans
    328. Colombo C, Miceli R, Lazar AJ, Perrone F, Pollock RE, Le Cesne A, Hartgrink HH, Cleton-Jansen AM, Domont J, Bonvalot S, Lev D, Gronchi A, Bov?e JV. CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study. Cancer. 2013 Oct 15; 119(20):3696-702. PMID: 23913621.
      Citations: 54     Fields:    Translation:Humans
    329. Kim KB, Cabanillas ME, Lazar AJ, Williams MD, Sanders DL, Ilagan JL, Nolop K, Lee RJ, Sherman SI. Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation. Thyroid. 2013 Oct; 23(10):1277-83. PMID: 23489023; PMCID: PMC3967415.
      Citations: 85     Fields:    Translation:HumansCTClinical Trials
    330. Fitzgibbons PL, Lazar AJ, Spencer S. Introducing new College of American Pathologists reporting templates for cancer biomarkers. Arch Pathol Lab Med. 2014 Feb; 138(2):157-8. PMID: 23808404.
      Citations: 3     Fields:    Translation:Humans
    331. Kluk MJ, Ashworth T, Wang H, Knoechel B, Mason EF, Morgan EA, Dorfman D, Pinkus G, Weigert O, Hornick JL, Chirieac LR, Hirsch M, Oh DJ, South AP, Leigh IM, Pourreyron C, Cassidy AJ, Deangelo DJ, Weinstock DM, Krop IE, Dillon D, Brock JE, Lazar AJ, Peto M, Cho RJ, Stoeck A, Haines BB, Sathayanrayanan S, Rodig S, Aster JC. Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. PLoS One. 2013; 8(6):e67306. PMID: 23825651; PMCID: PMC3688991.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    332. Rao P, Lahat G, Arnold C, Gavino AC, Lahat S, Hornick JL, Lev D, Lazar AJ. Angiosarcoma: a tissue microarray study with diagnostic implications. Am J Dermatopathol. 2013 Jun; 35(4):432-7. PMID: 23689692.
      Citations: 14     Fields:    Translation:HumansCells
    333. Lee N, Luthra R, Lopez-Terrada D, Wang WL, Lazar AJ. Retroperitoneal undifferentiated pleomorphic sarcoma having microsatellite instability associated with Muir-Torre syndrome: case report and review of literature. J Cutan Pathol. 2013 Aug; 40(8):730-3. PMID: 23672746.
      Citations: 3     Fields:    Translation:HumansCells
    334. Zhang Y, Young ED, Bill K, Belousov R, Peng T, Lazar AJ, Pollock RE, Simmons PJ, Lev D, Kolonin MG. Heterogeneity and immunophenotypic plasticity of malignant cells in human liposarcomas. Stem Cell Res. 2013 Sep; 11(2):772-81. PMID: 23770802; PMCID: PMC3737386.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    335. Park MS, Ravi V, Conley A, Patel SR, Trent JC, Lev DC, Lazar AJ, Wang WL, Benjamin RS, Araujo DM. The role of chemotherapy in advanced solitary fibrous tumors: a retrospective analysis. Clin Sarcoma Res. 2013 May 11; 3(1):7. PMID: 23663788; PMCID: PMC3660184.
      Citations: 28     
    336. Tseng WW, Somaiah N, Lazar AJ, Lev DC, Pollock RE. Novel systemic therapies in advanced liposarcoma: a review of recent clinical trial results. Cancers (Basel). 2013 May 10; 5(2):529-49. PMID: 24216990; PMCID: PMC3730323.
      Citations: 24     
    337. Al-Zaid T, Wang WL, Lopez-Terrada D, Lev D, Hornick JL, Hafeez Diwan A, Fletcher CD, Lazar AJ. Pleomorphic fibroma and dermal atypical lipomatous tumor: are they related? J Cutan Pathol. 2013 Apr; 40(4):379-84. PMID: 23506010.
      Citations:    Fields:    Translation:HumansCells
    338. Fong EL, Lamhamedi-Cherradi SE, Burdett E, Ramamoorthy V, Lazar AJ, Kasper FK, Farach-Carson MC, Vishwamitra D, Demicco EG, Menegaz BA, Amin HM, Mikos AG, Ludwig JA. Modeling Ewing sarcoma tumors in vitro with 3D scaffolds. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6500-5. PMID: 23576741; PMCID: PMC3631678.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    339. Plantinga MJ, Pascarelli KM, Merkel AS, Lazar AJ, von Mehren M, Lev D, Broccoli D. Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles. Mol Cancer Res. 2013 Jun; 11(6):557-67. PMID: 23505069.
      Citations: 10     Fields:    Translation:HumansCells
    340. Kurek KC, Pansuriya TC, van Ruler MA, van den Akker B, Luks VL, Verbeke SL, Kozakewich HP, Sciot R, Lev D, Lazar AJ, Fletcher CD, Bov?e JV. R132C IDH1 mutations are found in spindle cell hemangiomas and not in other vascular tumors or malformations. Am J Pathol. 2013 May; 182(5):1494-500. PMID: 23485734.
      Citations: 8     Fields:    Translation:Humans
    341. Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, Lev D, Le LQ, Parada LF, McKay RM. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 2013 Feb 28; 152(5):1077-90. PMID: 23434321; PMCID: PMC3594500.
      Citations: 81     Fields:    Translation:HumansCells
    342. Hoffman A, Ghadimi MP, Demicco EG, Creighton CJ, Torres K, Colombo C, Peng T, Lusby K, Ingram D, Hornick JL, Wang WL, Ravi V, Lazar AJ, Lev D, Pollock RE. Localized and metastatic myxoid/round cell liposarcoma: clinical and molecular observations. Cancer. 2013 May 15; 119(10):1868-77. PMID: 23401071.
      Citations: 43     Fields:    Translation:Humans
    343. Lusby K, Savannah KB, Demicco EG, Zhang Y, Ghadimi MP, Young ED, Colombo C, Lam R, Dogan TE, Hornick JL, Lazar AJ, Hunt KK, Anderson ML, Creighton CJ, Lev D, Pollock RE. Uterine leiomyosarcoma management, outcome, and associated molecular biomarkers: a single institution's experience. Ann Surg Oncol. 2013 Jul; 20(7):2364-72. PMID: 23334251; PMCID: PMC3913478.
      Citations: 32     Fields:    Translation:Humans
    344. Wang WL, Katz D, Araujo DM, Ravi V, Ludwig JA, Trent JC, Patel SR, Lin PP, Guadagnolo A, Dei Tos AP, Lewis VO, Lev D, Pollock RE, Zagars GK, Benjamin RS, Madewell JE, Lazar AJ, L?pez-Terrada D. Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy. Clin Sarcoma Res. 2012 Dec 29; 2(1):25. PMID: 23272660; PMCID: PMC3599544.
      Citations: 5     
    345. Greaves WO, Verma S, Patel KP, Davies MA, Barkoh BA, Galbincea JM, Yao H, Lazar AJ, Aldape KD, Medeiros LJ, Luthra R. Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma. J Mol Diagn. 2013 Mar; 15(2):220-6. PMID: 23273605; PMCID: PMC5707183.
      Citations: 84     Fields:    Translation:HumansCells
    346. Wang S, Li J, Manapuram RK, Menodiado FM, Ingram DR, Twa MD, Lazar AJ, Lev DC, Pollock RE, Larin KV. Noncontact measurement of elasticity for the detection of soft-tissue tumors using phase-sensitive optical coherence tomography combined with a focused air-puff system. Opt Lett. 2012 Dec 15; 37(24):5184-6. PMID: 23258046; PMCID: PMC4589295.
      Citations: 38     Fields:    Translation:HumansCells
    347. Torres KE, Ravi V, Kin K, Yi M, Guadagnolo BA, May CD, Arun BK, Hunt KK, Lam R, Lahat G, Hoffman A, Cormier JN, Feig BW, Lazar AJ, Lev D, Pollock RE. Long-term outcomes in patients with radiation-associated angiosarcomas of the breast following surgery and radiotherapy for breast cancer. Ann Surg Oncol. 2013 Apr; 20(4):1267-74. PMID: 23224828; PMCID: PMC5036516.
      Citations: 34     Fields:    Translation:Humans
    348. Suchak R, Wang WL, Prieto VG, Ivan D, Lazar AJ, Brenn T, Calonje E. Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations. Am J Surg Pathol. 2012 Dec; 36(12):1883-91. PMID: 23026931.
      Citations: 18     Fields:    Translation:Humans
    349. Doyle LA, Wang WL, Dal Cin P, Lopez-Terrada D, Mertens F, Lazar AJ, Fletcher CD, Hornick JL. MUC4 is a sensitive and extremely useful marker for sclerosing epithelioid fibrosarcoma: association with FUS gene rearrangement. Am J Surg Pathol. 2012 Oct; 36(10):1444-51. PMID: 22982887.
      Citations: 42     Fields:    Translation:HumansCells
    350. Patel SP, Lazar AJ, Papadopoulos NE, Liu P, Infante JR, Glass MR, Vaughn CS, LoRusso PM, Cohen RB, Davies MA, Kim KB. Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma. Cancer. 2013 Feb 15; 119(4):799-805. PMID: 22972589.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    351. Ghadimi MP, Lopez G, Torres KE, Belousov R, Young ED, Liu J, Brewer KJ, Hoffman A, Lusby K, Lazar AJ, Pollock RE, Lev D. Targeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumors. Mol Cancer Ther. 2012 Aug; 11(8):1758-69. PMID: 22848094; PMCID: PMC3416967.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    352. Yang J, Kantrow S, Sai J, Hawkins OE, Boothby M, Ayers GD, Young ED, Demicco EG, Lazar AJ, Lev D, Richmond A. INK4a/ARF [corrected] inactivation with activation of the NF-?B/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma. Cancer Res. 2012 Sep 15; 72(18):4682-95. PMID: 22836752; PMCID: PMC3459578.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    353. Brewer Savannah KJ, Demicco EG, Lusby K, Ghadimi MP, Belousov R, Young E, Zhang Y, Huang KL, Lazar AJ, Hunt KK, Pollock RE, Creighton CJ, Anderson ML, Lev D. Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma. Clin Cancer Res. 2012 Sep 01; 18(17):4633-45. PMID: 22821997; PMCID: PMC3432751.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    354. Kim J, Lazar AJ, Davies MA, Homsi J, Papadopoulos NE, Hwu WJ, Bedikian AY, Woodman SE, Patel SP, Hwu P, Kim KB. BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma. J Cutan Pathol. 2012 Sep; 39(9):821-5. PMID: 22809251; PMCID: PMC3881367.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    355. Zimmerman MA, Rahman NT, Yang D, Lahat G, Lazar AJ, Pollock RE, Lev D, Liu K. Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance. Cancer Res. 2012 Sep 15; 72(18):4724-32. PMID: 22805310; PMCID: PMC3564959.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    356. Foo WC, Liegl-Atzwanger B, Lazar AJ. Pathology of gastrointestinal stromal tumors. Clin Med Insights Pathol. 2012; 5:23-33. PMID: 22855636; PMCID: PMC3408870.
      Citations: 15     
    357. Wang WL, Patel NR, Caragea M, Hogendoorn PC, Hornick JL, Lazar AJ, L?pez-Terrada D. Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma. Mod Pathol. 2012 Oct; 25(10):1378-83. PMID: 22766791.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    358. McKay KM, Doyle LA, Lazar AJ, Hornick JL. Expression of ERG, an Ets family transcription factor, distinguishes cutaneous angiosarcoma from histological mimics. Histopathology. 2012 Nov; 61(5):989-91. PMID: 22716285.
      Citations: 8     Fields:    Translation:Humans
    359. Alexander LJ, Paravar T, Duvic M, Prieto V, Hymes SR. Annular plaques: An unusual manifestation of graft-versus-host disease. Dermatol Online J. 2012 Jun 15; 18(6):4. PMID: 22747928.
      Citations: 1     Fields:    Translation:Humans
    360. Tseng WW, Demicco EG, Lazar AJ, Lev DC, Pollock RE. Lymphocyte composition and distribution in inflammatory, well-differentiated retroperitoneal liposarcoma: clues to a potential adaptive immune response and therapeutic implications. Am J Surg Pathol. 2012 Jun; 36(6):941-4. PMID: 22446945.
      Citations: 12     Fields:    Translation:HumansCells
    361. Demicco EG, Park MS, Araujo DM, Fox PS, Bassett RL, Pollock RE, Lazar AJ, Wang WL. Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model. Mod Pathol. 2012 Sep; 25(9):1298-306. PMID: 22575866.
      Citations: 114     Fields:    Translation:Humans
    362. Demicco EG, Maki RG, Lev DC, Lazar AJ. New therapeutic targets in soft tissue sarcoma. Adv Anat Pathol. 2012 May; 19(3):170-80. PMID: 22498582; PMCID: PMC3353406.
      Citations: 20     Fields:    Translation:Humans
    363. Colombo C, Foo WC, Whiting D, Young ED, Lusby K, Pollock RE, Lazar AJ, Lev D. FAP-related desmoid tumors: a series of 44 patients evaluated in a cancer referral center. Histol Histopathol. 2012 05; 27(5):641-9. PMID: 22419028.
      Citations: 12     Fields:    Translation:Humans
    364. Al-Zaid T, Ditelberg JS, Prieto VG, Lev D, Luthra R, Davies MA, Diwan AH, Wang WL, Lazar AJ. Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors. J Cutan Pathol. 2012 May; 39(5):493-9. PMID: 22486434.
      Citations: 8     Fields:    Translation:Humans
    365. Li Q, Li M, Wang YL, Fauzee NJ, Yang Y, Pan J, Yang L, Lazar A. RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway. Cell Physiol Biochem. 2012; 29(3-4):361-72. PMID: 22508044.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    366. Shalin SC, Sakharpe A, Lyle S, Lev D, Calonje E, Lazar AJ. p53 staining correlates with tumor type and location in sebaceous neoplasms. Am J Dermatopathol. 2012 Apr; 34(2):129-35; quiz 136-8. PMID: 22441365; PMCID: PMC3313553.
      Citations: 8     Fields:    Translation:HumansCells
    367. Ghadimi MP, Young ED, Belousov R, Zhang Y, Lopez G, Lusby K, Kivlin C, Demicco EG, Creighton CJ, Lazar AJ, Pollock RE, Lev D. Survivin is a viable target for the treatment of malignant peripheral nerve sheath tumors. Clin Cancer Res. 2012 May 01; 18(9):2545-57. PMID: 22407831; PMCID: PMC3932367.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    368. Wang WL, Evans HL, Meis JM, Liegl-Atzwanger B, Bovee JV, Goldblum JR, Billings SD, Rubin BP, Lazar AJ, L?pez-Terrada D. FUS rearrangements are rare in 'pure' sclerosing epithelioid fibrosarcoma. Mod Pathol. 2012 Jun; 25(6):846-53. PMID: 22388756.
      Citations: 10     Fields:    Translation:HumansCells
    369. Shvartsbeyn M, Lazar AJ, Lopez-Terrada D, Meehan SA. Pseudocystic dermatofibrosarcoma protuberans: report of two cases and demonstration of COL1A1-PDGFB rearrangement. J Cutan Pathol. 2012 Mar; 39(3):356-60. PMID: 22335595.
      Citations:    Fields:    Translation:Humans
    370. Wang WL, Nero C, Pappo A, Lev D, Lazar AJ, L?pez-Terrada D. CTNNB1 genotyping and APC screening in pediatric desmoid tumors: a proposed algorithm. Pediatr Dev Pathol. 2012 Sep-Oct; 15(5):361-7. PMID: 22372443.
      Citations: 13     Fields:    Translation:Humans
    371. Zhang P, Bill K, Liu J, Young E, Peng T, Bolshakov S, Hoffman A, Song Y, Demicco EG, Terrada DL, Creighton CJ, Anderson ML, Lazar AJ, Calin GG, Pollock RE, Lev D. MiR-155 is a liposarcoma oncogene that targets casein kinase-1a and enhances ?-catenin signaling. Cancer Res. 2012 Apr 01; 72(7):1751-62. PMID: 22350414; PMCID: PMC3319789.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    372. Edris B, Mikels A, Lee CH, Steigen SE, Zhu S, Montgomery KD, Lazar AJ, Lev D, Fletcher JA, Beck AH, West RB, Nusse R, van de Rijn M, Espinosa I, M?hlenberg T. ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour. J Pathol. 2012 Jun; 227(2):223-33. PMID: 22294416; PMCID: PMC3992120.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    373. Woodman SE, Lazar AJ, Aldape KD, Davies MA. New strategies in melanoma: molecular testing in advanced disease. Clin Cancer Res. 2012 Mar 01; 18(5):1195-200. PMID: 22275506; PMCID: PMC4109407.
      Citations: 17     Fields:    Translation:HumansCells
    374. Katz D, Boonsirikamchai P, Choi H, Lazar AJ, Wang WL, Xiao L, Park MS, Ravi V, Benjamin RS, Araujo DM. Efficacy of first-line doxorubicin and ifosfamide in myxoid liposarcoma. Clin Sarcoma Res. 2012 Jan 24; 2(1):2. PMID: 22587772; PMCID: PMC3351704.
      Citations: 22     
    375. Davies MA, Fox PS, Papadopoulos NE, Bedikian AY, Hwu WJ, Lazar AJ, Prieto VG, Culotta KS, Madden TL, Xu Q, Huang S, Deng W, Ng CS, Gupta S, Liu W, Dancey JE, Wright JJ, Bassett RL, Hwu P, Kim KB. Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma. Clin Cancer Res. 2012 Feb 15; 18(4):1120-8. PMID: 22223528; PMCID: PMC3906678.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    376. Chen LL, Chen X, Choi H, Sang H, Chen LC, Zhang H, Gouw L, Andtbacka RH, Chan BK, Rodesch CK, Jimenez A, Cano P, Jones KA, Oyedeji CO, Martins T, Hill HR, Schumacher J, Willmore C, Scaife CL, Ward JH, Morton K, Randall RL, Lazar AJ, Patel S, Trent JC, Frazier ML, Lin P, Jensen P, Benjamin RS. Exploiting antitumor immunity to overcome relapse and improve remission duration. Cancer Immunol Immunother. 2012 Jul; 61(7):1113-24. PMID: 22198309; PMCID: PMC3378844.
      Citations: 20     Fields:    Translation:HumansCellsCTClinical Trials
    377. Jakob JA, Bassett RL, Ng CS, Curry JL, Joseph RW, Alvarado GC, Rohlfs ML, Richard J, Gershenwald JE, Kim KB, Lazar AJ, Hwu P, Davies MA. NRAS mutation status is an independent prognostic factor in metastatic melanoma. Cancer. 2012 Aug 15; 118(16):4014-23. PMID: 22180178; PMCID: PMC3310961.
      Citations: 257     Fields:    Translation:Humans
    378. Trufant J, Kurz W, Frankel A, Muthusamy V, McKinnon W, Greenblatt M, Lazar A, Cook D, Bosenberg M. Familial multiple pilomatrixomas as a presentation of attenuated adenomatosis polyposis coli. J Cutan Pathol. 2012 Apr; 39(4):440-3. PMID: 22150579.
      Citations: 6     Fields:    Translation:Humans
    379. Dumont SN, Lazar AJ, Bridge JA, Benjamin RS, Trent JC. PAX3/7-FOXO1 fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization. J Cancer Res Clin Oncol. 2012 Feb; 138(2):213-20. PMID: 22089931; PMCID: PMC3932368.
      Citations: 7     Fields:    Translation:Humans
    380. Berri RN, Baumann DP, Madewell JE, Lazar A, Pollock RE. Desmoid tumor: current multidisciplinary approaches. Ann Plast Surg. 2011 Nov; 67(5):551-64. PMID: 21587055.
      Citations: 14     Fields:    Translation:Humans
    381. Demicco EG, Torres KE, Ghadimi MP, Colombo C, Bolshakov S, Hoffman A, Peng T, Wang WL, Lev D, Lazar AJ, Bov?e JV. Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma. Mod Pathol. 2012 Feb; 25(2):212-21. PMID: 22020193; PMCID: PMC3266971.
      Citations: 36     Fields:    Translation:HumansCells
    382. Dumont AG, Rink L, Godwin AK, Miettinen M, Joensuu H, Strosberg JR, Gronchi A, Corless CL, Goldstein D, Rubin BP, Maki RG, Lazar AJ, Lev D, Trent JC, von Mehren M. A nonrandom association of gastrointestinal stromal tumor (GIST) and desmoid tumor (deep fibromatosis): case series of 28 patients. Ann Oncol. 2012 May; 23(5):1335-1340. PMID: 21994214; PMCID: PMC3493136.
      Citations: 18     Fields:    Translation:Humans
    383. Wang WL, Bones-Valentin RA, Prieto VG, Pollock RE, Lev DC, Lazar AJ. Sarcoma metastases to the skin: a clinicopathologic study of 65 patients. Cancer. 2012 Jun 01; 118(11):2900-4. PMID: 21989966.
      Citations: 7     Fields:    Translation:Humans
    384. Demicco EG, Lazar AJ. Clinicopathologic considerations: how can we fine tune our approach to sarcoma? Semin Oncol. 2011 Oct; 38 Suppl 3:S3-18. PMID: 22055969.
      Citations: 6     Fields:    Translation:HumansCells
    385. Lahat G, Zhang P, Zhu QS, Torres K, Ghadimi M, Smith KD, Wang WL, Lazar AJ, Lev D. The expression of c-Met pathway components in unclassified pleomorphic sarcoma/malignant fibrous histiocytoma (UPS/MFH): a tissue microarray study. Histopathology. 2011 Sep; 59(3):556-61. PMID: 22034893.
      Citations: 14     Fields:    Translation:Humans
    386. Tanas MR, Sboner A, Oliveira AM, Erickson-Johnson MR, Hespelt J, Hanwright PJ, Flanagan J, Luo Y, Fenwick K, Natrajan R, Mitsopoulos C, Zvelebil M, Hoch BL, Weiss SW, Debiec-Rychter M, Sciot R, West RB, Lazar AJ, Ashworth A, Reis-Filho JS, Lord CJ, Gerstein MB, Rubin MA, Rubin BP. Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma. Sci Transl Med. 2011 Aug 31; 3(98):98ra82. PMID: 21885404.
      Citations: 117     Fields:    Translation:Humans
    387. Colombo C, Creighton CJ, Ghadimi MP, Bolshakov S, Warneke CL, Zhang Y, Lusby K, Zhu S, Lazar AJ, West RB, van de Rijn M, Lev D. Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target. J Pathol. 2011 Dec; 225(4):574-82. PMID: 21826666.
      Citations: 10     Fields:    Translation:HumansCells
    388. Xie X, Ghadimi MP, Young ED, Belousov R, Zhu QS, Liu J, Lopez G, Colombo C, Peng T, Reynoso D, Hornick JL, Lazar AJ, Lev D. Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma. Clin Cancer Res. 2011 Sep 15; 17(18):5901-12. PMID: 21821699; PMCID: PMC3176924.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    389. Colombo C, Bolshakov S, Hajibashi S, Lopez-Terrada L, Wang WL, Rao P, Benjamin RS, Lazar AJ, Lev D. 'Difficult to diagnose' desmoid tumours: a potential role for CTNNB1 mutational analysis. Histopathology. 2011 Aug; 59(2):336-40. PMID: 21884214.
      Citations: 10     Fields:    Translation:Humans
    390. Wang X, Asmann YW, Erickson-Johnson MR, Oliveira JL, Zhang H, Moura RD, Lazar AJ, Lev D, Bill K, Lloyd RV, Yaszemski MJ, Maran A, Oliveira AM. High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma. Genes Chromosomes Cancer. 2011 Nov; 50(11):849-58. PMID: 21793095.
      Citations: 24     Fields:    Translation:HumansCells
    391. Torres KE, Liu J, Young E, Huang KL, Ghadimi M, Lusby K, Lazar AJ, Lev D. Expression of 'drugable' tyrosine kinase receptors in malignant peripheral nerve sheath tumour: potential molecular therapeutic targets for a chemoresistant cancer. Histopathology. 2011 Jul; 59(1):156-9. PMID: 21771036; PMCID: PMC4532392.
      Citations: 6     Fields:    Translation:Humans
    392. Swaby MG, Evans HL, Fletcher CD, Prieto VG, Patel KU, Lev DC, Lazar AJ, Wang WL, L?pez-Terrada D. Dermatofibrosarcoma protuberans with unusual sarcomatous transformation: a series of 4 cases with molecular confirmation. Am J Dermatopathol. 2011 Jun; 33(4):354-60. PMID: 21478726.
      Citations: 2     Fields:    Translation:Humans
    393. Diwan AH, Lazar AJ. Nevoid melanoma. Clin Lab Med. 2011 Jun; 31(2):243-53. PMID: 21549238.
      Citations: 4     Fields:    Translation:Humans
    394. Ghadimi MP, Al-Zaid T, Madewell J, Peng T, Colombo C, Hoffman A, Creighton CJ, Zhang Y, Zhang A, Lazar AJ, Pollock RE, Lev D. Diagnosis, management, and outcome of patients with dedifferentiated liposarcoma systemic metastasis. Ann Surg Oncol. 2011 Dec; 18(13):3762-70. PMID: 21614627.
      Citations: 23     Fields:    Translation:Humans
    395. Ghadimi MP, Liu P, Peng T, Bolshakov S, Young ED, Torres KE, Colombo C, Hoffman A, Broccoli D, Hornick JL, Lazar AJ, Pisters P, Pollock RE, Lev D. Pleomorphic liposarcoma: clinical observations and molecular variables. Cancer. 2011 Dec 01; 117(23):5359-69. PMID: 21598240; PMCID: PMC3161152.
      Citations: 27     Fields:    Translation:Humans
    396. Torres KE, Zhu QS, Bill K, Lopez G, Ghadimi MP, Xie X, Young ED, Liu J, Nguyen T, Bolshakov S, Belousov R, Wang S, Lahat G, Liu J, Hernandez B, Lazar AJ, Lev D. Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors. Clin Cancer Res. 2011 Jun 15; 17(12):3943-55. PMID: 21540237; PMCID: PMC3117912.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    397. Park MS, Patel SR, Ludwig JA, Trent JC, Conrad CA, Lazar AJ, Wang WL, Boonsirikamchai P, Choi H, Wang X, Benjamin RS, Araujo DM. Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor. Cancer. 2011 Nov 01; 117(21):4939-47. PMID: 21480200; PMCID: PMC3135685.
      Citations: 72     Fields:    Translation:Humans
    398. Huh WW, Yuen C, Munsell M, Hayes-Jordan A, Lazar AJ, Patel S, Wang WL, Barahmani N, Okcu MF, Hicks J, Debelenko L, Spunt SL. Liposarcoma in children and young adults: a multi-institutional experience. Pediatr Blood Cancer. 2011 Dec 15; 57(7):1142-6. PMID: 21394894; PMCID: PMC3134599.
      Citations: 17     Fields:    Translation:Humans
    399. Hsu A, Esmaeli B, Hayek B, Hossain MG, Shinder R, Lazar AJ, McCarty JH. Analysis of av integrin protein expression in human eyelid and periorbital squamous cell carcinomas. J Cutan Pathol. 2011 Jul; 38(7):570-5. PMID: 21375561.
      Citations: 2     Fields:    Translation:Humans
    400. Sakharpe A, Lahat G, Gulamhusein T, Liu P, Bolshakov S, Nguyen T, Zhang P, Belousov R, Young E, Xie X, Rao P, Hornick JL, Lazar AJ, Pollock RE, Lev D. Epithelioid sarcoma and unclassified sarcoma with epithelioid features: clinicopathological variables, molecular markers, and a new experimental model. Oncologist. 2011; 16(4):512-22. PMID: 21357725; PMCID: PMC3228127.
      Citations: 17     Fields:    Translation:HumansCells
    401. Dayrit JF, Wang WL, Goh SG, Ramdial PK, Lazar AJ, Calonje E. T-cell-rich angiomatoid polypoid pseudolymphoma of the skin: a clinicopathologic study of 17 cases and a proposed nomenclature. J Cutan Pathol. 2011 Jun; 38(6):475-82. PMID: 21352259.
      Citations: 2     Fields:    Translation:HumansCells
    402. Carbajal EF, Baranov SA, Manne VG, Young ED, Lazar AJ, Lev DC, Pollock RE, Larin KV. Revealing retroperitoneal liposarcoma morphology using optical coherence tomography. J Biomed Opt. 2011 Feb; 16(2):020502. PMID: 21361658.
      Citations: 6     Fields:    Translation:Humans
    403. Wang WL, Roy A, Lopez-Terrada D, Lazar AJ, Fletcher CD, Coffin CM, Hornick JL, Mari?o-Enr?quez A. Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. Am J Surg Pathol. 2011 Jan; 35(1):135-44. PMID: 21164297.
      Citations: 75     Fields:    Translation:HumansCells
    404. Wang WL, Conley A, Reynoso D, Nolden L, Lazar AJ, George S, Trent JC. Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor. Cancer Chemother Pharmacol. 2011 Jan; 67 Suppl 1:S15-24. PMID: 21181476.
      Citations: 23     Fields:    Translation:Humans
    405. Hoffman A, Lazar AJ, Pollock RE, Lev D. New frontiers in the treatment of liposarcoma, a therapeutically resistant malignant cohort. Drug Resist Updat. 2011 Feb; 14(1):52-66. PMID: 21169051.
      Citations: 23     Fields:    Translation:HumansAnimals
    406. Hu Q, Gao F, Tian W, Ruteshouser EC, Wang Y, Lazar A, Stewart J, Strong LC, Behringer RR, Huff V. Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation. J Clin Invest. 2011 Jan; 121(1):174-83. PMID: 21123950; PMCID: PMC3007149.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    407. Lopez G, Torres K, Liu J, Hernandez B, Young E, Belousov R, Bolshakov S, Lazar AJ, Slopis JM, McCutcheon IE, McConkey D, Lev D. Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors. Cancer Res. 2011 Jan 01; 71(1):185-96. PMID: 21084276; PMCID: PMC3064267.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    408. Peng T, Zhang P, Liu J, Nguyen T, Bolshakov S, Belousov R, Young ED, Wang X, Brewer K, Oliveira AM, Lazar AJ, Lev D, L?pez-Terrada DH. An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors. Lab Invest. 2011 Mar; 91(3):392-403. PMID: 21060307; PMCID: PMC3058694.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    409. Zhu QS, Rosenblatt K, Huang KL, Lahat G, Brobey R, Bolshakov S, Nguyen T, Ding Z, Belousov R, Bill K, Luo X, Lazar A, Dicker A, Mills GB, Hung MC, Lev D. Vimentin is a novel AKT1 target mediating motility and invasion. Oncogene. 2011 Jan 27; 30(4):457-70. PMID: 20856200; PMCID: PMC3010301.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    410. Hunt KK, Yang J, Lazar AJ, Torres KE, Lev DC, Nykter M, Pollock RE, Trent J, Zhang W, Ylip?? A. Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors. Cancer. 2011 Jan 15; 117(2):380-9. PMID: 20818650; PMCID: PMC3008331.
      Citations: 16     Fields:    Translation:HumansCells
    411. Gupta A, Roy S, Lazar AJ, Wang WL, McAuliffe JC, Reynoso D, McMahon J, Taguchi T, Floris G, Debiec-Rychter M, Schoffski P, Trent JA, Debnath J, Rubin BP. Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST). Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14333-8. PMID: 20660757; PMCID: PMC2922542.
      Citations: 100     Fields:    Translation:Humans
    412. Yang J, Eddy JA, Pan Y, Hategan A, Tabus I, Wang Y, Cogdell D, Price ND, Pollock RE, Lazar AJ, Hunt KK, Trent JC, Zhang W. Integrated proteomics and genomics analysis reveals a novel mesenchymal to epithelial reverting transition in leiomyosarcoma through regulation of slug. Mol Cell Proteomics. 2010 Nov; 9(11):2405-13. PMID: 20651304; PMCID: PMC2984227.
      Citations: 33     Fields:    Translation:Humans
    413. Brown JG, Folpe AL, Rao P, Lazar AJ, Paner GP, Gupta R, Parakh R, Cheville JC, Amin MB. Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases. Am J Surg Pathol. 2010 Jul; 34(7):942-9. PMID: 20534992.
      Citations: 29     Fields:    Translation:Humans
    414. Powers MP, Wang WL, Hernandez VS, Patel KS, Lev DC, Lazar AJ, L?pez-Terrada DH. Detection of myxoid liposarcoma-associated FUS-DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay. Mod Pathol. 2010 Oct; 23(10):1307-15. PMID: 20581806.
      Citations: 22     Fields:    Translation:Humans
    415. Lahat G, Dhuka AR, Hallevi H, Xiao L, Zou C, Smith KD, Phung TL, Pollock RE, Benjamin R, Hunt KK, Lazar AJ, Lev D. Angiosarcoma: clinical and molecular insights. Ann Surg. 2010 Jun; 251(6):1098-106. PMID: 20485141.
      Citations: 73     Fields:    Translation:Humans
    416. Weaver J, Rao P, Goldblum JR, Joyce MJ, Turner SL, Lazar AJ, Tubbs RR, Rubin BP, L?pez-Terada D. Can MDM2 analytical tests performed on core needle biopsy be relied upon to diagnose well-differentiated liposarcoma? Mod Pathol. 2010 Oct; 23(10):1301-6. PMID: 20495536.
      Citations: 17     Fields:    Translation:Humans
    417. Wang S, Ren W, Liu J, Lahat G, Torres K, Lopez G, Lazar AJ, Hayes-Jordan A, Liu K, Bankson J, Hazle JD, Lev D. TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivo. Clin Cancer Res. 2010 May 01; 16(9):2591-604. PMID: 20406839; PMCID: PMC2967255.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    418. Lahat G, Zhu QS, Huang KL, Wang S, Bolshakov S, Liu J, Torres K, Langley RR, Lazar AJ, Hung MC, Lev D. Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies. PLoS One. 2010 Apr 16; 5(4):e10105. PMID: 20419128; PMCID: PMC2855704.
      Citations: 99     Fields:    Translation:AnimalsCells
    419. Rubin BP, Cooper K, Fletcher CD, Folpe AL, Gannon FH, Hunt JL, Lazar AJ, Montag AG, Peabody TD, Pollock RE, Reith JD, Qualman SJ, Rosenberg AE, Weiss SW, Krausz T, Members of the Cancer Committee, College of American Pathologists. Protocol for the examination of specimens from patients with tumors of soft tissue. Arch Pathol Lab Med. 2010 Apr; 134(4):e31-9. PMID: 20367297.
      Citations: 13     Fields:    Translation:Humans
    420. Wang WL, Patel KU, Coleman NM, Smith-Zagone MJ, Ivan D, Reed JA, Lazar AJ, Prieto VG, L?pez-Terrada D. COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin. Am J Dermatopathol. 2010 Apr; 32(2):149-53. PMID: 19940748.
      Citations:    Fields:    Translation:HumansCells
    421. Reynoso D, Subbiah V, Trent JC, Guadagnolo BA, Lazar AJ, Benjamin R, Pollock RE, Ludwig JA. Neoadjuvant treatment of soft-tissue sarcoma: a multimodality approach. J Surg Oncol. 2010 Mar 15; 101(4):327-33. PMID: 20187067.
      Citations: 9     Fields:    Translation:Humans
    422. Rutkowski P, Van Glabbeke M, Rankin CJ, Ruka W, Rubin BP, Debiec-Rychter M, Lazar A, Gelderblom H, Sciot R, Lopez-Terrada D, Hohenberger P, van Oosterom AT, Schuetze SM, European Organisation for Research and Treatment of Cancer Soft Tissue/Bone Sarcoma Group, Southwest Oncology Group. Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials. J Clin Oncol. 2010 Apr 01; 28(10):1772-9. PMID: 20194851; PMCID: PMC3040044.
      Citations: 87     Fields:    Translation:Humans
    423. Hantschke M, Mentzel T, Palmedo G, Calonje E, Lazar AJ, Kutzner H, R?tten A. Cutaneous clear cell sarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 12 cases emphasizing its distinction from dermal melanoma. Am J Surg Pathol. 2010 Feb; 34(2):216-22. PMID: 20087159; PMCID: PMC5798433.
      Citations: 22     Fields:    Translation:HumansCells
    424. Rubin BP, Blanke CD, Demetri GD, Dematteo RP, Fletcher CD, Goldblum JR, Lasota J, Lazar A, Maki RG, Miettinen M, Noffsinger A, Washington MK, Krausz T, Cancer Committee, College of American Pathologists. Protocol for the examination of specimens from patients with gastrointestinal stromal tumor. Arch Pathol Lab Med. 2010 Feb; 134(2):165-70. PMID: 20121601.
      Citations: 21     Fields:    Translation:Humans
    425. Ostler DA, Prieto VG, Reed JA, Deavers MT, Lazar AJ, Ivan D. Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases. Mod Pathol. 2010 Apr; 23(4):567-73. PMID: 20118912.
      Citations: 26     Fields:    Translation:Humans
    426. Powers M, Zhang W, Lopez-Terrada D, Czerniak BA, Lazar AJ. The molecular pathology of sarcomas. Cancer Biomark. 2010; 9(1-6):475-91. PMID: 22112491.
      Citations: 10     Fields:    Translation:HumansAnimals
    427. Shalin SC, Lyle S, Calonje E, Lazar AJ. Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications. Histopathology. 2010 Jan; 56(1):133-47. PMID: 20055911; PMCID: PMC2805836.
      Citations: 31     Fields:    Translation:Humans
    428. Davies MA, Stemke-Hale K, Lin E, Tellez C, Deng W, Gopal YN, Woodman SE, Calderone TC, Ju Z, Lazar AJ, Prieto VG, Aldape K, Mills GB, Gershenwald JE. Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma. Clin Cancer Res. 2009 Dec 15; 15(24):7538-7546. PMID: 19996208; PMCID: PMC2805170.
      Citations: 113     Fields:    
    429. Lazar AJ, Lahat G, Myers SE, Smith KD, Zou C, Wang WL, Lopez-Terrada D, Lev D. Validation of potential therapeutic targets in alveolar soft part sarcoma: an immunohistochemical study utilizing tissue microarray. Histopathology. 2009 Dec; 55(6):750-5. PMID: 20002771.
      Citations: 10     Fields:    Translation:Humans
    430. Mito JK, Riedel RF, Dodd L, Lahat G, Lazar AJ, Dodd RD, Stangenberg L, Eward WC, Hornicek FJ, Yoon SS, Brigman BE, Jacks T, Lev D, Mukherjee S, Kirsch DG. Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. PLoS One. 2009 Nov 30; 4(11):e8075. PMID: 19956606; PMCID: PMC2779485.
      Citations: 47     Fields:    Translation:HumansAnimals
    431. Lahat G, Tuvin D, Wei C, Wang WL, Pollock RE, Anaya DA, Bekele BN, Corely L, Lazar AJ, Pisters PW, Lev D. Molecular prognosticators of complex karyotype soft tissue sarcoma outcome: a tissue microarray-based study. Ann Oncol. 2010 May; 21(5):1112-20. PMID: 19875755.
      Citations: 11     Fields:    Translation:HumansCells
    432. Diwan AH, Lazar AJ. Nevoid Melanoma. Surg Pathol Clin. 2009 Sep; 2(3):521-33. PMID: 26838537.
      Citations:    Fields:    
    433. Katz D, Lazar A, Lev D. Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways. Expert Rev Mol Med. 2009 Oct 19; 11:e30. PMID: 19835664.
      Citations: 42     Fields:    Translation:HumansCells
    434. Torres-Cabala CA, Wang WL, Trent J, Yang D, Chen S, Galbincea J, Kim KB, Woodman S, Davies M, Plaza JA, Nash JW, Prieto VG, Lazar AJ, Ivan D. Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type. Mod Pathol. 2009 Nov; 22(11):1446-56. PMID: 19718013; PMCID: PMC4120323.
      Citations: 48     Fields:    Translation:Humans
    435. Woodman SE, Trent JC, Stemke-Hale K, Lazar AJ, Pricl S, Pavan GM, Fermeglia M, Gopal YN, Yang D, Podoloff DA, Ivan D, Kim KB, Papadopoulos N, Hwu P, Mills GB, Davies MA. Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates. Mol Cancer Ther. 2009 Aug; 8(8):2079-85. PMID: 19671763; PMCID: PMC3346953.
      Citations: 68     Fields:    Translation:HumansCells
    436. Ivan D, Prieto VG, Esmaeli B, Wistuba II, Tang X, Lazar AJ. Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma. J Cutan Pathol. 2010 Feb; 37(2):231-6. PMID: 19614729.
      Citations: 5     Fields:    Translation:Humans
    437. Blazer DG, Lazar AJ, Xing Y, Askew RL, Feig BW, Pisters PW, Pollock RE, Lev D, Hunt KK, Cormier JN. Clinical outcomes of molecularly confirmed clear cell sarcoma from a single institution and in comparison with data from the Surveillance, Epidemiology, and End Results registry. Cancer. 2009 Jul 01; 115(13):2971-9. PMID: 19402173.
      Citations: 6     Fields:    Translation:Humans
    438. Lazar AJ, Hajibashi S, Lev D. Desmoid tumor: from surgical extirpation to molecular dissection. Curr Opin Oncol. 2009 Jul; 21(4):352-9. PMID: 19436199.
      Citations: 11     Fields:    Translation:Humans
    439. Lahat G, Dhuka AR, Lahat S, Lazar AJ, Lewis VO, Lin PP, Feig B, Cormier JN, Hunt KK, Pisters PW, Pollock RE, Lev D. Complete soft tissue sarcoma resection is a viable treatment option for select elderly patients. Ann Surg Oncol. 2009 Sep; 16(9):2579-86. PMID: 19557478.
      Citations: 22     Fields:    Translation:Humans
    440. Wang WL, Mayordomo E, Zhang W, Hernandez VS, Tuvin D, Garcia L, Lev DC, Lazar AJ, L?pez-Terrada D. Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts). Mod Pathol. 2009 Sep; 22(9):1201-9. PMID: 19561568.
      Citations: 52     Fields:    Translation:Humans
    441. Lahat G, Dhuka AR, Lahat S, Smith KD, Pollock RE, Hunt KK, Ravi V, Lazar AJ, Lev D. Outcome of locally recurrent and metastatic angiosarcoma. Ann Surg Oncol. 2009 Sep; 16(9):2502-9. PMID: 19551444.
      Citations: 18     Fields:    Translation:Humans
    442. Subbiah V, Anderson P, Lazar AJ, Burdett E, Raymond K, Ludwig JA. Ewing's sarcoma: standard and experimental treatment options. Curr Treat Options Oncol. 2009 Apr; 10(1-2):126-40. PMID: 19533369.
      Citations: 65     Fields:    Translation:Humans
    443. Zou C, Smith KD, Liu J, Lahat G, Myers S, Wang WL, Zhang W, McCutcheon IE, Slopis JM, Lazar AJ, Pollock RE, Lev D. Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg. 2009 Jun; 249(6):1014-22. PMID: 19474676.
      Citations: 108     Fields:    Translation:Humans
    444. Pomahac B, Garcia JA, Lazar AJ, Tilney N, Orgill DP. The skin allograft revisited: a potentially permanent wound coverage option in the critically ill patient. Plast Reconstr Surg. 2009 Jun; 123(6):1755-1758. PMID: 19483575.
      Citations: 3     Fields:    Translation:Humans
    445. Zou CY, Smith KD, Zhu QS, Liu J, McCutcheon IE, Slopis JM, Meric-Bernstam F, Peng Z, Bornmann WG, Mills GB, Lazar AJ, Pollock RE, Lev D. Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor. Mol Cancer Ther. 2009 May; 8(5):1157-68. PMID: 19417153.
      Citations: 42     Fields:    Translation:HumansCells
    446. Wang WL, Hornick JL, Mallipeddi R, Zelger BG, Rother JD, Yang D, Lev DC, Trent JC, Prieto VG, Brenn T, Robson A, Calonje E, Lazar AJ. Cutaneous and subcutaneous metastases of gastrointestinal stromal tumors: a series of 5 cases with molecular analysis. Am J Dermatopathol. 2009 May; 31(3):297-300. PMID: 19384074.
      Citations: 7     Fields:    Translation:Humans
    447. Lahat G, Lazar A, Wang X, Wang WL, Zhu QS, Hunt KK, Pollock RE, Lev D. Increased vascular endothelial growth factor-C expression is insufficient to induce lymphatic metastasis in human soft-tissue sarcomas. Clin Cancer Res. 2009 Apr 15; 15(8):2637-46. PMID: 19351758.
      Citations: 8     Fields:    Translation:HumansCells
    448. Liegl B, Hornick JL, Lazar AJ. Contemporary pathology of gastrointestinal stromal tumors. Hematol Oncol Clin North Am. 2009 Feb; 23(1):49-68, vii-viii. PMID: 19248970.
      Citations: 12     Fields:    Translation:Humans
    449. Yang D, Wang S, Brooks C, Dong Z, Schoenlein PV, Kumar V, Ouyang X, Xiong H, Lahat G, Hayes-Jordan A, Lazar A, Pollock R, Lev D, Liu K. IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression. Cancer Res. 2009 Feb 01; 69(3):1080-8. PMID: 19155307; PMCID: PMC2633427.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    450. McAuliffe JC, Hunt KK, Lazar AJ, Choi H, Qiao W, Thall P, Pollock RE, Benjamin RS, Trent JC. A randomized, phase II study of preoperative plus postoperative imatinib in GIST: evidence of rapid radiographic response and temporal induction of tumor cell apoptosis. Ann Surg Oncol. 2009 Apr; 16(4):910-9. PMID: 18953611; PMCID: PMC5647649.
      Citations: 67     Fields:    Translation:HumansCTClinical Trials
    451. Lazar AJ, Woodman SE, Kim K, Ross M, Hwu P, Quint?s-Cardama A. Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib. Nat Clin Pract Oncol. 2008 Dec; 5(12):737-40. PMID: 18936790.
      Citations: 36     Fields:    Translation:Humans
    452. Weaver J, Goldblum JR, Turner S, Tubbs RR, Wang WL, Lazar AJ, Rubin BP. Detection of MDM2 gene amplification or protein expression distinguishes sclerosing mesenteritis and retroperitoneal fibrosis from inflammatory well-differentiated liposarcoma. Mod Pathol. 2009 Jan; 22(1):66-70. PMID: 18836421.
      Citations: 13     Fields:    Translation:Humans
    453. Lazar AJ, Tuvin D, Hajibashi S, Habeeb S, Bolshakov S, Mayordomo-Aranda E, Warneke CL, Lopez-Terrada D, Pollock RE, Lev D. Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors. Am J Pathol. 2008 Nov; 173(5):1518-27. PMID: 18832571; PMCID: PMC2570141.
      Citations: 134     Fields:    Translation:HumansCells
    454. Yang J, Du X, Lazar AJ, Pollock R, Hunt K, Chen K, Hao X, Trent J, Zhang W. Genetic aberrations of gastrointestinal stromal tumors. Cancer. 2008 Oct 01; 113(7):1532-43. PMID: 18671247; PMCID: PMC2651090.
      Citations: 31     Fields:    Translation:Humans
    455. Davies MA, Stemke-Hale K, Tellez C, Calderone TL, Deng W, Prieto VG, Lazar AJ, Gershenwald JE, Mills GB. A novel AKT3 mutation in melanoma tumours and cell lines. Br J Cancer. 2008 Oct 21; 99(8):1265-8. PMID: 18813315; PMCID: PMC2570525.
      Citations: 114     Fields:    Translation:HumansCells
    456. Ivan D, Diwan AH, Lazar AJ, Prieto VG. The usefulness of p63 detection for differentiating primary from metastatic skin adenocarcinomas. J Cutan Pathol. 2008 Sep; 35(9):880-1. PMID: 18796086.
      Citations:    Fields:    
    457. Ren W, Korchin B, Lahat G, Wei C, Bolshakov S, Nguyen T, Merritt W, Dicker A, Lazar A, Sood A, Pollock RE, Lev D. Combined vascular endothelial growth factor receptor/epidermal growth factor receptor blockade with chemotherapy for treatment of local, uterine, and metastatic soft tissue sarcoma. Clin Cancer Res. 2008 Sep 01; 14(17):5466-75. PMID: 18765538.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    458. Jin Z, Lahat G, Korchin B, Nguyen T, Zhu QS, Wang X, Lazar AJ, Trent J, Pollock RE, Lev D. Midkine enhances soft-tissue sarcoma growth: a possible novel therapeutic target. Clin Cancer Res. 2008 Aug 15; 14(16):5033-42. PMID: 18698021.
      Citations: 17     Fields:    Translation:HumansAnimals
    459. Yang J, Du X, Chen K, Lazar AJ, Trent J, Lev D, Pollock R, Hao X, Hunt K, Zhang W, Ylip?? A. Genetic aberrations in soft tissue leiomyosarcoma. Cancer Lett. 2009 Mar 08; 275(1):1-8. PMID: 18649996; PMCID: PMC2674272.
      Citations: 40     Fields:    Translation:Humans
    460. Wang WL, Mayordomo E, Czerniak BA, Abruzzo LV, Dal Cin P, Araujo DM, Lev DC, Lazar AJ, L?pez-Terrada D. Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma. Mod Pathol. 2008 Nov; 21(11):1303-10. PMID: 18587326.
      Citations: 5     Fields:    Translation:HumansCells
    461. Rothberg BE, Moeder CB, Kluger H, Halaban R, Elder DE, Murphy GF, Lazar A, Prieto V, Duncan LM, Rimm DL. Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions. Mod Pathol. 2008 Sep; 21(9):1121-9. PMID: 18552823; PMCID: PMC2570478.
      Citations: 10     Fields:    Translation:HumansCells
    462. Lahat G, Tuvin D, Wei C, Anaya DA, Bekele BN, Lazar AJ, Pisters PW, Lev D, Pollock RE. New perspectives for staging and prognosis in soft tissue sarcoma. Ann Surg Oncol. 2008 Oct; 15(10):2739-48. PMID: 18521685.
      Citations: 43     Fields:    Translation:Humans
    463. Singh RS, Grayson W, Redston M, Diwan AH, Warneke CL, McKee PH, Lev D, Lyle S, Calonje E, Lazar AJ. Site and tumor type predicts DNA mismatch repair status in cutaneous sebaceous neoplasia. Am J Surg Pathol. 2008 Jun; 32(6):936-42. PMID: 18551751.
      Citations: 15     Fields:    Translation:HumansCells
    464. Lahat G, Lazar A, Lev D. Sarcoma epidemiology and etiology: potential environmental and genetic factors. Surg Clin North Am. 2008 Jun; 88(3):451-81, v. PMID: 18514694.
      Citations: 40     Fields:    Translation:Humans
    465. McAuliffe JC, Wang WL, Pavan GM, Pricl S, Yang D, Chen SS, Lazar AJ, Pollock RE, Trent JC. Unlucky number 13? Differential effects of KIT exon 13 mutation in gastrointestinal stromal tumors. Mol Oncol. 2008 Aug; 2(2):161-3. PMID: 19383335; PMCID: PMC5527764.
      Citations: 8     Fields:    Translation:Humans
    466. Robson A, Lazar AJ, Ben Nagi J, Hanby A, Grayson W, Feinmesser M, Granter SR, Seed P, Warneke CL, McKee PH, Calonje E. Primary cutaneous apocrine carcinoma: a clinico-pathologic analysis of 24 cases. Am J Surg Pathol. 2008 May; 32(5):682-90. PMID: 18347508.
      Citations: 28     Fields:    Translation:Humans
    467. Ren W, Korchin B, Zhu QS, Wei C, Dicker A, Heymach J, Lazar A, Pollock RE, Lev D. Epidermal growth factor receptor blockade in combination with conventional chemotherapy inhibits soft tissue sarcoma cell growth in vitro and in vivo. Clin Cancer Res. 2008 May 01; 14(9):2785-95. PMID: 18451246.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    468. Rebhun RB, Lazar AJ, Fidler IJ, Gershenwald JE. Impact of sentinel lymphadenectomy on survival in a murine model of melanoma. Clin Exp Metastasis. 2008; 25(3):191-9. PMID: 18264782.
      Citations: 8     Fields:    Translation:AnimalsCells
    469. Wang Q, Prieto V, Esmaeli B, Kolda T, Lazar A, Ivan D, Diwan AH. Cellular blue nevi of the eyelid: A possible diagnostic pitfall. J Am Acad Dermatol. 2008 Feb; 58(2):257-60. PMID: 18222322.
      Citations:    Fields:    Translation:Humans
    470. Euscher ED, Deavers MT, Lopez-Terrada D, Lazar AJ, Silva EG, Malpica A. Uterine tumors with neuroectodermal differentiation: a series of 17 cases and review of the literature. Am J Surg Pathol. 2008 Feb; 32(2):219-28. PMID: 18223324.
      Citations: 20     Fields:    Translation:Humans
    471. Kleinbaum EP, Lazar AJ, Tamborini E, Mcauliffe JC, Sylvestre PB, Sunnenberg TD, Strong L, Chen LL, Choi H, Benjamin RS, Zhang W, Trent JC. Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor. Int J Cancer. 2008 Feb 01; 122(3):711-8. PMID: 17943734.
      Citations: 20     Fields:    Translation:Humans
    472. Uzquiano MC, Prieto VG, Nash JW, Ivan DS, Gong Y, Lazar AJ, Diwan AH. Metastatic basal cell carcinoma exhibits reduced actin expression. Mod Pathol. 2008 May; 21(5):540-3. PMID: 18223552.
      Citations: 7     Fields:    Translation:Humans
    473. Diwan AH, Skelton HG, Horenstein MG, Kelly DR, Barrett TL, Bussian AH, Sanders DY, Lazar AJ, Prieto VG, Smith KJ. Dermatofibrosarcoma protuberans and giant cell fibroblastoma exhibit CD99 positivity. J Cutan Pathol. 2008 Jul; 35(7):647-50. PMID: 18201229.
      Citations: 1     Fields:    Translation:Humans
    474. Fuhr U, Frank D, Aarnoutse RE, Klaassen T, Lazar A, Seeringer A, Doroshyenko O, Kirchheiner JC, Abdulrazik F, Schmeisser N, Lehmann C, Hein W, Burger DM, Jetter A, Wyen C, Sch?mig E, F?tkenheuer G. Effect of an antiretroviral regimen containing ritonavir boosted lopinavir on intestinal and hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected patients. Clin Pharmacol Ther. 2008 Jul; 84(1):75-82. PMID: 18183034.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    475. Kotiligam D, Lazar AJ, Pollock RE, Lev D. Desmoid tumor: a disease opportune for molecular insights. Histol Histopathol. 2008 01; 23(1):117-26. PMID: 17952864.
      Citations: 33     Fields:    Translation:HumansCells
    476. Lazar AJ, Das P, Tuvin D, Korchin B, Zhu Q, Jin Z, Warneke CL, Zhang PS, Hernandez V, Lopez-Terrada D, Pisters PW, Pollock RE, Lev D. Angiogenesis-promoting gene patterns in alveolar soft part sarcoma. Clin Cancer Res. 2007 Dec 15; 13(24):7314-21. PMID: 18094412.
      Citations: 30     Fields:    Translation:Humans
    477. Trent JC, Lazar AJ, Zhang W. Molecular approaches to resolve diagnostic dilemmas: the case of gastrointestinal stromal tumor and leiomyosarcoma. Future Oncol. 2007 Dec; 3(6):629-37. PMID: 18041915.
      Citations: 4     Fields:    Translation:Humans
    478. McAuliffe JC, Lazar AJ, Yang D, Steinert DM, Qiao W, Thall PF, Raymond AK, Benjamin RS, Trent JC. Association of intratumoral vascular endothelial growth factor expression and clinical outcome for patients with gastrointestinal stromal tumors treated with imatinib mesylate. Clin Cancer Res. 2007 Nov 15; 13(22 Pt 1):6727-34. PMID: 18006774.
      Citations: 11     Fields:    Translation:Humans
    479. Kunishige JH, Hymes SR, Madkan V, Wyatt AJ, Uptmore D, Lazar AJ, Giralt S, Rady P, Tyring S. Epidermodysplasia verruciformis in the setting of graft-versus-host disease. J Am Acad Dermatol. 2007 Nov; 57(5 Suppl):S78-80. PMID: 17938030.
      Citations: 3     Fields:    Translation:Humans
    480. Patel KU, Szabo SS, Hernandez VS, Prieto VG, Abruzzo LV, Lazar AJ, L?pez-Terrada D. Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex reverse transcription polymerase chain reaction and fluorescence in situ hybridization assays. Hum Pathol. 2008 Feb; 39(2):184-93. PMID: 17950782.
      Citations: 41     Fields:    Translation:HumansCells
    481. Kantrow SM, Ivan D, Williams MD, Prieto VG, Lazar AJ. Metastasizing adenocarcinoma and multiple neoplastic proliferations arising in a nevus sebaceus. Am J Dermatopathol. 2007 Oct; 29(5):462-6. PMID: 17890915.
      Citations: 7     Fields:    Translation:Humans
    482. Lazar AJ, Lyle S, Calonje E. Sebaceous neoplasia and Torre-Muir syndrome. Curr Diagn Pathol. 2007 Aug; 13(4):301-319. PMID: 18670585; PMCID: PMC2128686.
      Citations: 18     
    483. Fan YS, Carr RA, Sanders DS, Smith AP, Lazar AJ, Calonje E. Characteristic Ber-EP4 and EMA expression in sebaceoma is immunohistochemically distinct from basal cell carcinoma. Histopathology. 2007 Jul; 51(1):80-6. PMID: 17593083.
      Citations: 6     Fields:    Translation:Humans
    484. Lazar AJ, Trent JC, Lev D. Sarcoma molecular testing: diagnosis and prognosis. Curr Oncol Rep. 2007 Jul; 9(4):309-15. PMID: 17588356.
      Citations: 4     Fields:    Translation:Humans
    485. Khalifeh I, Taraif S, Reed JA, Lazar AF, Diwan AH, Prieto VG. A subgroup of melanocytic nevi on the distal lower extremity (ankle) shares features of acral nevi, dysplastic nevi, and melanoma in situ: a potential misdiagnosis of melanoma in situ. Am J Surg Pathol. 2007 Jul; 31(7):1130-6. PMID: 17592281.
      Citations: 1     Fields:    Translation:Humans
    486. Ivan D, Nash JW, Prieto VG, Calonje E, Lyle S, Diwan AH, Lazar AJ. Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin. J Cutan Pathol. 2007 Jun; 34(6):474-80. PMID: 17518775.
      Citations: 10     Fields:    Translation:Humans
    487. Das P, Kotilingam D, Korchin B, Liu J, Yu D, Lazar AJ, Pollock RE, Lev D. High prevalence of p53 exon 4 mutations in soft tissue sarcoma. Cancer. 2007 Jun 01; 109(11):2323-33. PMID: 17429838.
      Citations: 17     Fields:    Translation:Humans
    488. Goddard DS, Magee CC, Lazar AJ, Miller DM. Nephrogenic fibrosing dermopathy with recurrence after allograft failure. J Am Acad Dermatol. 2007 May; 56(5 Suppl):S109-11. PMID: 17434031.
      Citations: 1     Fields:    Translation:Humans
    489. Lev D, Kotilingam D, Wei C, Ballo MT, Zagars GK, Pisters PW, Lazar AA, Patel SR, Benjamin RS, Pollock RE. Optimizing treatment of desmoid tumors. J Clin Oncol. 2007 May 01; 25(13):1785-91. PMID: 17470870.
      Citations: 84     Fields:    Translation:Humans
    490. Doherty SD, Giancola A, Nash J, Lazar A, Duvic M. Papulo-vesicular eruption. Dermatol Online J. 2007 May 01; 13(2):24. PMID: 17498443.
      Citations:    Fields:    Translation:Humans
    491. Perna AG, Ostler DA, Ivan D, Lazar AJ, Diwan AH, Prieto VG, Reed JA. Renal cell carcinoma marker (RCC-Ma) is specific for cutaneous metastasis of renal cell carcinoma. J Cutan Pathol. 2007 May; 34(5):381-5. PMID: 17448192.
      Citations: 9     Fields:    Translation:Humans
    492. Hannay JA, Liu J, Zhu QS, Bolshakov SV, Li L, Pisters PW, Lazar AJ, Yu D, Pollock RE, Lev D. Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation. Mol Cancer Ther. 2007 May; 6(5):1650-60. PMID: 17513613.
      Citations: 59     Fields:    Translation:HumansCells
    493. Ivan D, Bengana C, Lazar AJ, Diwan AH, Prieto VG. Merkel cell tumor in a trichilemmal cyst: collision or association? Am J Dermatopathol. 2007 Apr; 29(2):180-3. PMID: 17414443.
      Citations:    Fields:    Translation:HumansCells
    494. Cosme-Blanco W, Shen MF, Lazar AJ, Pathak S, Lozano G, Multani AS, Chang S. Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence. EMBO Rep. 2007 May; 8(5):497-503. PMID: 17396137; PMCID: PMC1866197.
      Citations: 83     Fields:    Translation:AnimalsCells
    495. Bieniek R, Lazar AJ, Photopoulos C, Lyle S. Sebaceous tumours contain a subpopulation of cells expressing the keratin 15 stem cell marker. Br J Dermatol. 2007 Feb; 156(2):378-80. PMID: 17223883.
      Citations: 8     Fields:    Translation:HumansCells
    496. May SA, Jones D, Medeiros LJ, Duvic M, Prieto VG, Lazar AJ. Oral-cutaneous CD4-positive T-cell lymphoma: a study of two patients. Am J Dermatopathol. 2007 Feb; 29(1):62-7. PMID: 17284964.
      Citations: 6     Fields:    Translation:HumansCells
    497. Nash JW, Barrett TL, Kies M, Ross MI, Sneige N, Diwan AH, Lazar AJ. Metastatic hidradenocarcinoma with demonstration of Her-2/neu gene amplification by fluorescence in situ hybridization: potential treatment implications. J Cutan Pathol. 2007 Jan; 34(1):49-54. PMID: 17214855.
      Citations: 15     Fields:    Translation:Humans
    498. Prieto VG, Mourad-Zeidan AA, Melnikova V, Johnson MM, Lopez A, Diwan AH, Lazar AJ, Shen SS, Zhang PS, Reed JA, Gershenwald JE, Raz A, Bar-Eli M. Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma. Clin Cancer Res. 2006 Nov 15; 12(22):6709-15. PMID: 17121890.
      Citations: 32     Fields:    Translation:HumansCells
    499. Liu J, Zhan M, Hannay JA, Das P, Bolshakov SV, Kotilingam D, Yu D, Lazar AF, Pollock RE, Lev D. Wild-type p53 inhibits nuclear factor-kappaB-induced matrix metalloproteinase-9 promoter activation: implications for soft tissue sarcoma growth and metastasis. Mol Cancer Res. 2006 Nov; 4(11):803-10. PMID: 17077165.
      Citations: 24     Fields:    Translation:HumansCells
    500. Wyatt AJ, Herzog CE, Lazar AJ. An erythematous plaque on the face. Clin Exp Dermatol. 2007 Jan; 32(1):123-4. PMID: 17059446.
      Citations:    Fields:    Translation:Humans
    501. Kotilingam D, Lev DC, Lazar AJ, Pollock RE. Staging soft tissue sarcoma: evolution and change. CA Cancer J Clin. 2006 Sep-Oct; 56(5):282-91; quiz 314-5. PMID: 17005597.
      Citations: 37     Fields:    Translation:Humans
    502. Lazar A, Abruzzo LV, Pollock RE, Lee S, Czerniak B. Molecular diagnosis of sarcomas: chromosomal translocations in sarcomas. Arch Pathol Lab Med. 2006 Aug; 130(8):1199-207. PMID: 16879024.
      Citations: 17     Fields:    Translation:Humans
    503. Natarajan E, Omobono JD, Guo Z, Hopkinson S, Lazar AJ, Brenn T, Jones JC, Rheinwald JG. A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence. Am J Pathol. 2006 Jun; 168(6):1821-37. PMID: 16723698; PMCID: PMC1606631.
      Citations: 31     Fields:    Translation:HumansCells
    504. Haluska FG, Tsao H, Wu H, Haluska FS, Lazar A, Goel V. Genetic alterations in signaling pathways in melanoma. Clin Cancer Res. 2006 Apr 01; 12(7 Pt 2):2301s-2307s. PMID: 16609049.
      Citations: 73     Fields:    Translation:HumansCells
    505. Takeda H, Lyle S, Lazar AJ, Zouboulis CC, Smyth I, Watt FM. Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med. 2006 Apr; 12(4):395-7. PMID: 16565724.
      Citations: 47     Fields:    Translation:HumansCells
    506. Goel VK, Lazar AJ, Warneke CL, Redston MS, Haluska FG. Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma. J Invest Dermatol. 2006 Jan; 126(1):154-60. PMID: 16417231.
      Citations: 137     Fields:    Translation:Humans
    507. Lazar AJ, Fletcher CD. Primitive nonneural granular cell tumors of skin: clinicopathologic analysis of 13 cases. Am J Surg Pathol. 2005 Jul; 29(7):927-34. PMID: 15958858.
      Citations: 16     Fields:    Translation:Humans
    508. Abimelec P, Dumontier C, Lazar A. Full thickness skin graft for nail unit reconstruction. J Hand Surg Br. 2005 May; 30(2):194-8. PMID: 15757774.
      Citations: 3     Fields:    Translation:Humans
    509. Haskell HD, Haynes HA, McKee PH, Redston M, Granter SR, Lazar AJ. Basal cell carcinoma with matrical differentiation: a case study with analysis of beta-catenin. J Cutan Pathol. 2005 Mar; 32(3):245-50. PMID: 15701088.
      Citations: 2     Fields:    Translation:Humans
    510. Lazar AJ, Calonje E, Grayson W, Dei Tos AP, Mihm MC, Redston M, McKee PH. Pilomatrix carcinomas contain mutations in CTNNB1, the gene encoding beta-catenin. J Cutan Pathol. 2005 Feb; 32(2):148-57. PMID: 15606674.
      Citations: 29     Fields:    Translation:HumansCells
    511. Lepourcelet M, Tou L, Cai L, Sawada J, Lazar AJ, Glickman JN, Williamson JA, Everett AD, Redston M, Fox EA, Nakatani Y, Shivdasani RA. Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development. 2005 Jan; 132(2):415-27. PMID: 15604097.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    512. Lazar AJ, Fletcher CD. Distinctive dermal clear cell mesenchymal neoplasm: clinicopathologic analysis of five cases. Am J Dermatopathol. 2004 Aug; 26(4):273-9. PMID: 15249856.
      Citations: 2     Fields:    Translation:Humans
    513. Roehrig K, Lazar A, Fleisch M, Niederacher D, Bender HG, Dall P, Rein DT, Sch?ndorf T. Expression of the hyaluronan receptor RHAMM in endometrial carcinomas suggests a role in tumour progression and metastasis. J Cancer Res Clin Oncol. 2003 Mar; 129(3):161-4. PMID: 12712331.
      Citations: 34     Fields:    Translation:Humans
    514. Petrescu D, Bosman A, Olaru G, Alexandrescu M, Lazar A, G?dea V, G?dea E. [Our attitude in esophageal and gastric post-caustic lesions]. Chirurgia (Bucur). 2000 May-Jun; 95(3):273-7. PMID: 14768333.
      Citations: 1     Fields:    Translation:Humans
    515. Lazar A, Melges S, Altobeli C, Wendel S, Font?o-Wendel R. The absolute number of circulating CD34+ cells as the best predictor of peripheral hematopoietic stem cell yield. J Hematother. 1999 Jun; 8(3):255-62. PMID: 10417048.
      Citations: 5     Fields:    Translation:HumansCells
    516. Faulkner A, Chen X, Rush J, Horazdovsky B, Waechter CJ, Carman GM, Sternweis PC. The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae. J Biol Chem. 1999 May 21; 274(21):14831-7. PMID: 10329682.
      Citations: 45     Fields:    Translation:Animals
    517. Xie Z, Fang M, Rivas MP, Faulkner AJ, Sternweis PC, Engebrecht JA, Bankaitis VA. Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12346-51. PMID: 9770489; PMCID: PMC22834.
      Citations: 64     Fields:    Translation:AnimalsCells
    518. Paquet KJ, Gad HA, Lazar A, Koussouris P, Mercado MA, Heine WD, Jachman-Jahn V, Ruppert W. Analysis of factors affecting outcome after hepatectomy of patients with liver cirrhosis and small hepatocellular carcinoma. Eur J Surg. 1998 Jul; 164(7):513-9. PMID: 9696973.
      Citations: 12     Fields:    Translation:Humans
    519. Tracz W, Kokoszka M, Pieniazek P, Przewlocki T, Hlawaty M, Podolec P, Frasik W, Lazar A, Dziatkowiak A, Olszowska M. [Long-term observation of patients with biopsy proven myocarditis or dilated cardiomyopathy]. Przegl Lek. 1996; 53(10):726-30. PMID: 9091951.
      Citations:    Fields:    Translation:Humans
    520. Lazar A, Kuhn R, Paquet KJ. [Narrow-lumen mesocaval interposition shunt in liver cirrhosis and recurrent esophageal varices hemorrhage. Standard surgery of the future in failure of sclerotherapy?]. Dtsch Med Wochenschr. 1995 May 19; 120(20):707-12. PMID: 7758409.
      Citations:    Fields:    Translation:Humans
    521. Paquet KJ, Lazar A. Current therapeutic strategy in bleeding esophageal varices in babies and children and long-term results of endoscopic paravariceal sclerotherapy over twenty years. Eur J Pediatr Surg. 1994 Jun; 4(3):165-72. PMID: 8086394.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    522. Lazar A, Rambach W, Kuhn R, Paquet KJ. [Single hepatocellular carcinoma (phi < or = 5 cm) in liver cirrhosis. Early diagnosis and surgical removal]. Chirurg. 1993 Oct; 64(10):784-8. PMID: 8269741.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    523. Eisenfeld L, Silver H, McLaughlin J, Klevjer-Anderson P, Mayo D, Anderson J, Herson V, Krause P, Savidakis J, Lazar A, et al. Prevention of transfusion-associated cytomegalovirus infection in neonatal patients by the removal of white cells from blood. Transfusion. 1992 Mar-Apr; 32(3):205-9. PMID: 1313609.
      Citations: 11     Fields:    Translation:Humans
    524. Lazar A, Mercado MA, Gad HA, Paquet KJ. [Elective-selective Warren splenorenal shunt operation. Prognosis of liver function and esophageal varices hemorrhage after repeat sclerotherapy in liver cirrhosis]. Chirurg. 1991 Nov; 62(11):794-8; discussion 798-9. PMID: 1769259.
      Citations:    Fields:    Translation:Humans
    525. Cherry LM, Faulkner AJ, Grossberg LA, Balczon R. Kinetochore size variation in mammalian chromosomes: an image analysis study with evolutionary implications. J Cell Sci. 1989 Feb; 92 ( Pt 2):281-9. PMID: 2674167.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    526. Milea S, Ionescu S, Cosma E, Lazarovici H, Lazar A, Cretu V. [Screening questionaire useful in studies of the epidemiology of mental diseases in the infantile population of urban environments]. Rev Med Interna Neurol Psihiatr Neurochir Dermatovenerol Neurol Psihiatr Neurochir. 1978 Jan-Mar; 23(1):25-37. PMID: 653156.
      Citations:    Fields:    Translation:HumansPHPublic Health
    527. Zylber-Katz E, Lazar A, Weisman P. Electron microscopic studies on frog virus 3 infection in HeLa cells at permissive and non-permissive temperatures. Arch Gesamte Virusforsch. 1974; 45(4):376-81. PMID: 4474866.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    528. HRUBAN Z, LAZAR A, SLESERS A. Changes in serum proteins during methylcellulose-induced regression of Murphy-Sturm lymphosarcoma. Lab Invest. 1963 Jan; 12:25-32. PMID: 13955257.
      Citations:    Fields:    
    529. LAZAR A, LAZAR DC. Effect of methylcellulose on the Murphy-Sturm lymphosarcoma in rats. J Natl Cancer Inst. 1962 Jun; 28:1255-67. PMID: 14463069.
      Citations: 1     Fields:    Translation:Animals
    530. American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine. CA Cancer Journal for Clinicians.
    531. Sebaceous neoplasia and Torre-Muir syndrome. Current Diagnostic Pathology. 13:301-319.
    532. Line-scan Raman microscopy complements optical coherence tomography for tumor boundary detection. Laser Physics Letters. 11.
    533. Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation. Laboratory Investigation. 96:885-894.
    534. AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas. BMC Cancer. 15.
    535. Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival. Modern Pathology.
    536. Integrated molecular and clinical analysis of AKT activation in metastatic melanoma. Clinical Cancer Research. 15:7538-7546.
    537. Radiation-Associated Undifferentiated Pleomorphic Sarcoma is Associated with Worse Clinical Outcomes than Sporadic Lesions. Annals of Surgical Oncology.
    538. Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations. Human Pathology. 46:1015-1026.
    539. Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas. BMC Cancer. 15.
    540. Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade. Cancer Discovery. 6:827-837.
    541. Targeting the Notch pathway. Cancer.
    542. Modeling synovial sarcoma metastasis in the mouse. Journal of Experimental Medicine. 213:2989-3005.
    543. Analysis of Clinical and Molecular Factors Impacting Oncologic Outcomes in Undifferentiated Pleomorphic Sarcoma. Annals of Surgical Oncology. 1-9.
    544. Non-radiographic risk factors differentiating atypical lipomatous tumors from lipomas. Frontiers in Oncology. 7.
    545. A brief history and contemporary re-assessment of malignant fibrous histiocytoma. Diagnostic Histopathology. 17:340-347.
    546. Regulation of phospholipase d and its role in membrane traffic. FASEB Journal. 11.
    547. Unknown presentation. Dermatology Online Journal. 13.
    548. Myxofibrosarcoma. Surgical Oncology Clinics of North America. 25:775-788.
    549. Molecular Dermatopathology. 249-268.
    550. How do we make clinical molecular testing for cancer standard of care for pathology departments?. JNCCN Journal of the National Comprehensive Cancer Network. 14:787-792.
    551. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Medicine. 14.
    552. Primary cutaneous adnexal neoplasms and their metastatic look-alikes. Pathology Case Reviews. 12:61-69.
    553. Sarcoma Brain Metastases. Annals of Surgical Oncology. 1-6.
    554. PAX7 Expression in Rhabdomyosarcoma, Related Soft Tissue Tumors, and Small Round Blue Cell Neoplasms. American Journal of Surgical Pathology.
    555. Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. PLoS One. 8.
    556. EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis. Journal of Pathology. 232:308-318.
    557. Combining a focused air-puff system with phase-sensitive optical coherence tomography for the detection of soft-tissue tumors based on elasticity measurement.
    558. Dual roles of RNF2 in melanoma progression. Cancer Discovery. 5:1314-1327.
    559. Angiosarcoma. European journal of Clinical and Medical Oncology. 4:73-81.
    560. Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure. Cell Cycle. 14:2323-2332.
    561. Cutaneous nodular fasciitis with genetic analysis. Journal of Cutaneous Pathology. 43:1143-1149.
    562. Primary intracranial soft tissue sarcomas in children, adolescents, and young adults. Journal of Neuro-Oncology. 127:155-163.
    563. Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway. Molecular Cancer. 14.
    564. Pathology of desmoid tumors. 17-28.
    565. BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children. Modern Pathology. 28:575-586.
    566. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clinical Cancer Research. 21:2644-2651.
    567. Molecular Pathology of Bone and Soft Tissue Tumors. 325-359.
    568. The molecular pathology of sarcomas. 475-491.
    569. Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression. Scientific Reports. 6.
    570. Estrogen receptor alpha and androgen receptor are commonly expressed in well-differentiated liposarcoma. BMC Clinical Pathology. 14.
    571. Poly (ADP) ribose polymerase inhibition. Cancer Biology and Therapy. 17:129-138.
    572. Nevoid Melanoma. Surgical Pathology Clinics. 2:521-533.
    573. SAR405838. Clinical Cancer Research. 22:1150-1160.
    574. Computational analysis of optical coherence tomography images for the detection of soft tissue sarcomas.
    575. Clinical Observations and Molecular Variables of Primary Vascular Leiomyosarcoma. JAMA Surgery. 151:347-354.
    576. Clinicopathological features and clinical outcomes associated with TP53 and BRAFN on- V 600 mutations in cutaneous melanoma patients. Cancer.
    577. Erratum. Journal of Pathology. 233:320.
    578. Raman spectroscopy complements optical coherent tomography in tissue classification and cancer detection.
    579. NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma. Oncogene.
    580. Cancer Discovery. 6:202-216.
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