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LAZAR, ALEXANDER
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ALEXANDER LAZAR
Title
Professor
Institution
MD Anderson
Department
Pathology
Address
1515 Holcombe Blvd
Houston TX 77030-4009
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Nguyen TDT, Wang Y, Bui TN, Lazcano R, Ingram DR, Yi M, Vakulabharanam V, Luo L, Pina MA,
Karakas C
, Li M, Kettner NM, Somaiah N, Houghton PJ, Mawlawi O,
Lazar AJ
,
Hunt KK
,
Keyomarsi K
, Nguyen TDT, Wang Y, Bui TN, Lazcano R, Ingram DR, Yi M, Vakulabharanam V, Luo L, Pina MA, Karakas C, Li M, Kettner NM,
Somaiah N
, Hougton PJ,
Mawlawi O
, Lazar AJ, Hunt KK, Keyomarsi K. Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time. Cancer Res. 2023 Mar 15; 83(6):939-955.
PMID:
36603130
.
Citations:
Fields:
Neo
Neoplasms
Chagani S, De Macedo MP, Carapeto F, Wang F, Marzese DM, Wani K, Haydu LE,
Peng W
, Ong GT, Warren SE, Beechem JM, Hoon DSB,
Mills GB
,
Tetzlaff MT
,
Lazar AJ
,
Kwong LN
,
Davies MA
. MULTIPLATFORM ANALYSIS OF INTRATUMORAL PTEN HETEROGENEITY IN MELANOMA. J Invest Dermatol. 2023 Mar 03.
PMID:
36871660
.
Citations:
Fields:
Der
Dermatology
Romano G, Paradiso F, Li P, Shukla P, Barger LN, El Naggar O, Miller JP, Liang RJ, Helms TL,
Lazar AJ
,
Wargo JA
, Taraballi F, Costello JC,
Kwong LN
. Microparticle-delivered Cxcl9 prolongs Braf inhibitor efficacy in melanoma. Cancer Immunol Res. 2023 Feb 23.
PMID:
36820825
.
Citations:
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Birkness-Gartman JE, Wangsiricharoen S,
Lazar AJ
, Gross JM, Birkness-Gartman JE, Wangsiricharoen S, Lazar AJ, Gross JM. Oesophageal glomus tumours: rare neoplasms with aggressive clinical behaviour. Histopathology. 2023 Feb 14.
PMID:
36788021
.
Citations:
Fields:
Pat
Pathology
Nassif EF, Joseph CP, Lazcano R, Joseph JT, Thirasastr P,
Lazar AJ
,
Somaiah N
. Case report: Responses to the combination of gemcitabine with sirolimus in two patients with TSC-mutated sarcomas. Front Oncol. 2023; 13:1046442.
PMID:
36845725
; PMCID:
PMC9947835
.
Citations:
Keung EZ, Krause KJ, Maxwell J, Morris CD, Crago AM, Houdek MT, Kane J,
Lewis V
, Callegaro D, Miller B,
Lazar AJ
, Gladdy R, Raut CP, Fabbri N, Al-Refaie W, Fairweather M, Wong SL,
Roland CL
. ASO Visual Abstract: Sentinel Lymph Node Biopsy for Extremity and Truncal Soft Tissue Sarcomas-A Systematic Review of the Literature. Ann Surg Oncol. 2023 02; 30(2):970-971.
PMID:
36323987
.
Citations:
Barnhill R, van Laere S, Vermeulen P, Roman-Roman S, Gardrat S, Alsafadi S, Tarin M, Champenois G, Nicolas A, Matet A, Cassoux N, Servois V, Rodrigues M, Scolyer R,
Lazar A
, Romano E, Piperno-Neumann S, Mariani P, Lugassy C. L1CAM and laminin vascular network: Association with the high-risk replacement histopathologic growth pattern in uveal melanoma liver metastases. Lab Invest. 2022 11; 102(11):1214-1224.
PMID:
36775447
.
Citations:
1
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Hahn AW, Menk AV, Rivadeneira DB, Augustin RC, Xu M, Li J, Wu X, Mishra AK, Gide TN, Quek C, Zang Y, Spencer CN, Menzies AM, Daniel CR, Hudgens CW, Nowicki T, Haydu LE, Khan MAW, Gopalakrishnan V, Burton EM, Malke J, Simon JM,
Bernatchez C
,
Putluri N
,
Woodman SE
, Vashisht Gopal YN, Guerrieri R, Fischer GM, Wang J, Wani KM, Thompson JF, Lee JE,
Hwu P
, Ajami N,
Gershenwald JE
, Long GV, Scolyer RA,
Tetzlaff MT
,
Lazar AJ
, Schadendorf D,
Wargo JA
,
Kirkwood JM
, DeBerardinis RJ,
Liang H
,
Futreal A
, Zhang J, Wilmott JS,
Peng W
,
Davies MA
, Delgoffe GM, Najjar YG,
McQuade JL
. Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma. Clin Cancer Res. 2023 01 04; 29(1):154-164.
PMID:
36166093
.
Citations:
Barnhill RL, Elder DE, Piepkorn MW, Knezevich SR, Reisch LM, Eguchi MM, Bastian BC, Blokx W, Bosenberg M, Busam KJ, Carr R, Cochran A, Cook MG, Duncan LM, Elenitsas R, de la Fouchardi?re A, Gerami P, Johansson I, Ko J, Landman G,
Lazar AJ
, Lowe L, Massi D, Messina J, Mihic-Probst D, Parker DC, Schmidt B, Shea CR, Scolyer RA,
Tetzlaff M
, Xu X, Yeh I, Zembowicz A, Elmore JG. Revision of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis Classification Schema for Melanocytic Lesions: A Consensus Statement. JAMA Netw Open. 2023 01 03; 6(1):e2250613.
PMID:
36630138
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Traweek RS, Martin AN, Rajkot NF,
Guadagnolo BA
,
Bishop AJ
,
Lazar AJ
, Keung EZ,
Torres KE
,
Hunt KK
,
Feig BW
,
Roland CL
, Scally CP. ASO Visual Abstract: Re-Excision After Unplanned Excision of Soft Tissue Sarcoma Is Associated with High Morbidity and Limited Pathologic Identification of Residual Disease. Ann Surg Oncol. 2023 01; 30(1):492.
PMID:
36245056
.
Citations:
Vellano CP,
White MG
, Andrews MC, Chelvanambi M, Witt RG, Daniele JR, Titus M,
McQuade JL
, Conforti F, Burton EM, Lastrapes MJ, Ologun G, Cogdill AP, Morad G, Prieto P,
Lazar AJ
, Chu Y, Han G, Khan MAW, Helmink B,
Davies MA
,
Amaria RN
, Kovacs JJ,
Woodman SE
, Patel S,
Hwu P
, Peoples M, Lee JE, Cooper ZA, Zhu H, Gao G, Banerjee H, Lau M,
Gershenwald JE
,
Lucci A
, Keung EZ,
Ross MI
, Pala L, Pagan E, Segura RL, Liu Q, Borthwick MS, Lau E,
Yates MS
,
Westin SN
, Wani K,
Tetzlaff MT
, Haydu LE, Mahendra M, Ma X,
Logothetis C
, Kulstad Z, Johnson S, Hudgens CW, Feng N, Federico L, Long GV, Futreal PA,
Arur S
,
Tawbi HA
, Moran AE, Wang L, Heffernan TP, Marszalek JR,
Wargo JA
. Author Correction: Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy. Nature. 2023 Jan; 613(7945):E3.
PMID:
36627494
.
Citations:
Fields:
Sci
Science
Li Y, Lih TM, Dhanasekaran SM, Mannan R, Chen L, Cieslik M, Wu Y, Lu RJ, Clark DJ, Kolodziejczak I, Hong R, Chen S, Zhao Y, Chugh S, Caravan W, Naser Al Deen N, Hosseini N, Newton CJ, Krug K, Xu Y, Cho KC, Hu Y, Zhang Y, Kumar-Sinha C, Ma W, Calinawan A, Wyczalkowski MA, Wendl MC, Wang Y, Guo S, Zhang C, Le A, Dagar A, Hopkins A, Cho H, Leprevost FDV, Jing X, Teo GC, Liu W, Reimers MA, Pachynski R,
Lazar AJ
, Chinnaiyan AM, Van Tine BA, Zhang B, Rodland KD, Getz G, Mani DR, Wang P, Chen F, Hostetter G, Thiagarajan M, Linehan WM, Feny? D, Jewell SD, Omenn GS, Mehra R, Wiznerowicz M, Robles AI, Mesri M, Hiltke T, An E, Rodriguez H, Chan DW, Ricketts CJ, Nesvizhskii AI, Zhang H, Ding L, Clinical Proteomic Tumor Analysis Consortium. Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness. Cancer Cell. 2023 01 09; 41(1):139-163.e17.
PMID:
36563681
; PMCID:
PMC9839644
.
Citations:
Ronen S, Ko JS, Rubin BP, Kilpatrick SE, Wang WL,
Lazar AJ
, Goldblum JR, Billings SD. Superficial low-grade fibromyxoid sarcoma. J Cutan Pathol. 2023 Feb; 50(2):147-154.
PMID:
36074249
.
Citations:
Keung EZ, Krause KJ, Maxwell J, Morris CD, Crago AM, Houdek MT, Kane J,
Lewis V
, Callegaro D, Miller B,
Lazar AJ
, Gladdy R, Raut CP, Fabbri N, Al-Refaie W, Fairweather M, Wong SL,
Roland CL
. Sentinel Lymph Node Biopsy for Extremity and Truncal Soft Tissue Sarcomas: A Systematic Review of the Literature. Ann Surg Oncol. 2023 Feb; 30(2):958-967.
PMID:
36307665
.
Citations:
Lazcano R, Barreto CM, Salazar R, Carapeto F, Traweek RS, Leung CH, Gite S, Mehta J, Ingram DR, Wani KM, Vu KT, Parra ER, Lu W, Zhou J, Witt RG, Cope B, Thirasastr P, Lin HY, Scally CP,
Conley AP
,
Ratan R
, Livingston JA, Zarzour AM,
Ludwig J
,
Araujo D
,
Ravi V
,
Patel S
, Benjamin R,
Wargo J
,
Wistuba II
,
Somaiah N
,
Roland CL
, Keung EZ, Solis L, Wang WL,
Lazar AJ
, Nassif EF. The immune landscape of undifferentiated pleomorphic sarcoma. Front Oncol. 2022; 12:1008484.
PMID:
36313661
; PMCID:
PMC9597628
.
Citations:
Rubino F, Alvarez-Breckenridge C, Akdemir K,
Conley AP
,
Bishop AJ
, Wang WL,
Lazar AJ
,
Rhines LD
,
DeMonte F
,
Raza SM
. Prognostic molecular biomarkers in chordomas: A systematic review and identification of clinically usable biomarker panels. Front Oncol. 2022; 12:997506.
PMID:
36248987
; PMCID:
PMC9557284
.
Citations:
Cloutier JM, Ingram DR, Wani K,
Lazar AJ
, Wang WL. Frequent TRPS1 expression in synovial sarcoma is associated with SS18-SSX fusion oncoprotein activity. Hum Pathol. 2022 Dec; 130:88-94.
PMID:
36162599
.
Citations:
Simpson RC, Shanahan ER, Batten M, Reijers ILM, Read M, Silva IP, Versluis JM, Ribeiro R, Angelatos AS, Tan J, Adhikari C, Menzies AM, Saw RPM, Gonzalez M, Shannon KF, Spillane AJ, Velickovic R,
Lazar AJ
, Damania AV, Mishra AK, Chelvanambi M, Banerjee A, Ajami NJ,
Wargo JA
, Macia L, Holmes AJ, Wilmott JS, Blank CU, Scolyer RA, Long GV. Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome. Nat Med. 2022 11; 28(11):2344-2352.
PMID:
36138151
.
Citations:
Nathenson MJ, Hu J,
Ratan R
,
Somaiah N
, Hsu R, DeMaria PJ, Catoe HW, Pang A, Subhawong TK,
Amini B
, Sweet K, Feister K, Malik K, Jagannathan J, Braschi-Amirfarzan M, Sheren J, Caldas Y, Moreno Tellez C, Rosenberg AE, Lazar AJ, Maki RG, Benedetto P, Cohen J, Trent JC, Ravi V,
Patel S
, Wilky BA, Nathenson MJ, Hu J, Ratan R, Somaiah N, Hsu R, DeMaria PJ, Catoe HW, Pang A, Subhawong TK, Amini B, Sweet K, Feister K, Malik K, Jagannathan J, Braschi-Amirfarzan M, Sheren J, Caldas Y, Moreno Tellez C, Rosenberg AE,
Lazar AJ
, Maki RG, Benedetto P, Cohen J, Trent JC,
Ravi V
, Patel S, Wilky BA. Systemic Chemotherapies Retain Antitumor Activity in Desmoid Tumors Independent of Specific Mutations in CTNNB1 or APC: A Multi-institutional Retrospective Study. Clin Cancer Res. 2022 09 15; 28(18):4092-4104.
PMID:
35180772
; PMCID:
PMC9475245
.
Citations:
Fields:
Neo
Neoplasms
Traweek RS, Martin AN, Rajkot NF,
Guadagnolo BA
,
Bishop AJ
,
Lazar AJ
, Keung EZ,
Torres KE
,
Hunt KK
,
Feig BW
,
Roland CL
, Scally CP. Re-excision After Unplanned Excision of Soft Tissue Sarcoma is Associated with High Morbidity and Limited Pathologic Identification of Residual Disease. Ann Surg Oncol. 2023 Jan; 30(1):480-489.
PMID:
36085392
.
Citations:
Lazar AJ
, Demicco EG. Human and machine: Better at pathology together? Cancer Cell. 2022 08 08; 40(8):806-808.
PMID:
35944500
.
Citations:
Somaiah N
,
Conley AP
, Parra ER, Lin H,
Amini B
, Solis Soto L, Salazar R, Barreto C, Chen H, Gite S,
Haymaker C
, Nassif EF,
Bernatchez C
, Mitra A,
Livingston JA
,
Ravi V
,
Araujo DM
, Benjamin R,
Patel S
,
Zarzour MA
,
Sabir S
,
Lazar AJ
, Wang WL, Daw NC, Zhou X,
Roland CL
, Cooper ZA, Rodriguez-Canales J,
Futreal A
, Soria JC,
Wistuba II
,
Hwu P
. Durvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas: a single-centre phase 2 trial. Lancet Oncol. 2022 09; 23(9):1156-1166.
PMID:
35934010
.
Citations:
Bishop AJ
,
Amini B
, Lin H, Raza SM,
Patel S
,
Grosshans DR
,
Ghia A
, Farooqi A, Guadagnolo BA, Mitra D, Akdemir KC,
Lazar AJ
, Wang WL, Alvarez-Breckenridge C, Bird J, Rhines LD,
Somaiah N
,
Conley AP
. Immune Checkpoint Inhibitors Have Clinical Activity in Patients With Recurrent Chordoma. J Immunother. 2022 10 01; 45(8):374-378.
PMID:
35943386
; PMCID:
PMC9452485
.
Citations:
Warmke LM, Maloney N, Leung CH, Lin H, Lazar AJ, Wang WL, Warmke LM, Maloney N, Leung CH, Lin H,
Lazar AJ
, Wang WL. SATB2 Expression in Undifferentiated Pleomorphic Sarcomas of Bone. Am J Clin Pathol. 2022 08 04; 158(2):235-241.
PMID:
35311957
.
Citations:
Fields:
Pat
Pathology
Bonvalot S, Rutkowski PL, Thariat J, Carrère S, Ducassou A, Sunyach MP, Agoston P, Hong AM, Mervoyer A, Rastrelli M, Moreno V, Li RK, Tiangco BJ, Herráez AC, Gronchi A, Sy-Ortin T, Hohenberger P, de Baère T, Cesne AL, Helfre S, Saada-Bouzid E, Anghel RM, Kantor G, Montero A, Loong HH, Vergés R, Kacso G, Austen L, Servois VF, Wardelmann E, Dimitriu M, Said P, Lazar AJ, Bovée JVMG, Péchoux CL, Pápai Z, Bonvalot S, Rutkowski PL, Thariat J, Carrère S, Ducassou A, Sunyach MP, Agoston P, Hong AM, Mervoyer A, Rastrelli M, Moreno V, Li RK, Tiangco BJ, Herráez AC, Gronchi A, Sy-Ortin T, Hohenberger P, de Baère T, Cesne AL, Helfre S, Saada-Bouzid E, Anghel RM, Kantor G, Montero A, Loong HH, Vergés R, Kacso G, Austen L, Servois VF, Wardelmann E, Dimitriu M, Said P,
Lazar AJ
, Bovée JVMG, Péchoux CL, Pápai Z, Thariat J, Carr?re S, Sunyach MP, Agoston P, Moreno V, Tiangco BJ, Herr?ez AC, de Ba?re T, Kantor G, Verg?s R, Wardelmann E, Bov?e JVMG, P?choux CL, P?pai Z. Final Safety and Health-Related Quality of LIfe Results of the Phase 2/3 Act.In.Sarc Study With Preoperative NBTXR3 Plus Radiation Therapy Versus Radiation Therapy in Locally Advanced Soft-Tissue Sarcoma. Int J Radiat Oncol Biol Phys. 2022 11 01; 114(3):422-432.
PMID:
35850363
.
Citations:
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Andrews MC, Oba J, Wu CJ, Zhu H, Karpinets T, Creasy CA, Forget MA, Yu X, Song X, Mao X, Robertson AG, Romano G, Li P, Burton EM, Lu Y, Sloane RS, Wani KM,
Rai K
,
Lazar AJ
, Haydu LE, Bustos MA, Shen J, Chen Y, Morgan MB, Wargo JA, Kwong LN,
Haymaker CL
, Grimm EA,
Hwu P
, Hoon DSB, Zhang J,
Gershenwald JE
, Davies MA, Futreal PA, Bernatchez C, Woodman SE, Andrews MC, Oba J, Wu CJ, Zhu H, Karpinets T, Creasy CA, Forget MA, Yu X, Song X, Mao X, Robertson AG, Romano G, Li P, Burton EM, Lu Y, Sloane RS, Wani KM, Rai K, Lazar AJ, Haydu LE, Bustos MA, Shen J, Chen Y, Morgan MB,
Wargo JA
, Kwong LN, Haymaker CL, Grimm EA, Hwu P, Hoon DSB, Zhang J, Gershenwald JE, Davies MA, Futreal PA,
Bernatchez C
,
Woodman SE
, Forget MA. Multi-modal molecular programs regulate melanoma cell state. Nat Commun. 2022 07 09; 13(1):4000.
PMID:
35810190
; PMCID:
PMC9271073
.
Citations:
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Ravi V, Subramaniam A, Zheng J,
Amini B
, Trinh VA, Joseph J, Mennel RG,
Bishop AJ
,
Sturgis EM
, Goepfert RP, Yalamanchili S, Botello G, Stephen B,
Piha-Paul SA
,
Patel AB
, Lazar AJ, Conley AP, Benjamin RS, Patel SR, Futreal PA, Somaiah N, Naing A,
Ravi V
, Subramaniam A, Zheng J, Amini B, Trinh VA, Joseph J, Mennel RG, Bishop AJ, Sturgis EM, Goepfert RP, Yalamanchili S, Botello G, Stephen B, Piha-Paul SA, Patel AB,
Lazar AJ
,
Conley AP
, Benjamin RS,
Patel SR
, Futreal PA,
Somaiah N
,
Naing A
. Clinical activity of checkpoint inhibitors in angiosarcoma: A retrospective cohort study. Cancer. 2022 09 15; 128(18):3383-3391.
PMID:
35792683
.
Citations:
Fields:
Neo
Neoplasms
Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBO, Berti E, Bhagat G, Borges AM, Boyer D, Calaminici M, Chadburn A, Chan JKC, Cheuk W, Chng WJ, Choi JK, Chuang SS, Coupland SE, Czader M, Dave SS, de Jong D, Du MQ, Elenitoba-Johnson KS, Ferry J, Geyer J, Gratzinger D, Guitart J, Gujral S, Harris M, Harrison CJ, Hartmann S, Hochhaus A, Jansen PM, Karube K, Kempf W,
Khoury J
, Kimura H, Klapper W, Kovach AE, Kumar S, Lazar AJ, Lazzi S, Leoncini L, Leung N, Leventaki V, Li XQ, Lim MS, Liu WP, Louissaint A,
Marcogliese A
, Medeiros LJ, Michal M,
Miranda RN
, Mitteldorf C, Montes-Moreno S, Morice W, Nardi V, Naresh KN, Natkunam Y, Ng SB, Oschlies I, Ott G, Parrens M, Pulitzer M, Rajkumar SV, Rawstron AC, Rech K, Rosenwald A, Said J, Sarkozy C, Sayed S, Saygin C, Schuh A, Sewell W, Siebert R, Sohani AR, Tooze R, Traverse-Glehen A, Vega F, Vergier B, Wechalekar AD, Wood B, Xerri L, Xiao W, Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBO, Berti E, Bhagat G, Borges AM, Boyer D, Calaminici M, Chadburn A, Chan JKC, Cheuk W, Chng WJ, Choi JK, Chuang SS, Coupland SE, Czader M, Dave SS, de Jong D, Du MQ, Elenitoba-Johnson KS, Ferry J, Geyer J, Gratzinger D, Guitart J, Gujral S, Harris M, Harrison CJ, Hartmann S, Hochhaus A, Jansen PM, Karube K, Kempf W, Khoury J, Kimura H, Klapper W, Kovach AE, Kumar S,
Lazar AJ
, Lazzi S, Leoncini L, Leung N, Leventaki V, Li XQ, Lim MS, Liu WP, Louissaint A, Marcogliese A, Medeiros LJ, Michal M, Miranda RN, Mitteldorf C, Montes-Moreno S, Morice W, Nardi V, Naresh KN, Natkunam Y, Ng SB, Oschlies I, Ott G, Parrens M, Pulitzer M, Rajkumar SV, Rawstron AC, Rech K, Rosenwald A, Said J, Sarkozy C, Sayed S, Saygin C, Schuh A, Sewell W, Siebert R, Sohani AR, Tooze R, Traverse-Glehen A, Vega F, Vergier B, Wechalekar AD, Wood B, Xerri L, Xiao W, Anagnostopoulos I, Berti E, Hochhaus A, Mitteldorf C, Rosenwald A, Sarkozy C, Traverse-Glehen A, Vergier B. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia. 2022 07; 36(7):1720-1748.
PMID:
35732829
; PMCID:
PMC9214472
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Gounder MM, Agaram NP, Trabucco SE, Robinson V, Ferraro RA, Millis SZ, Krishnan A, Lee J, Attia S, Abida W, Drilon A, Chi P, Angelo SP, Dickson MA, Keohan ML, Kelly CM, Agulnik M, Chawla SP, Choy E, Chugh R, Meyer CF, Myer PA, Moore JL, Okimoto RA, Pollock RE, Ravi V, Singh AS,
Somaiah N
, Wagner AJ, Healey JH, Frampton GM, Venstrom JM, Ross JS, Ladanyi M, Singer S, Brennan MF, Schwartz GK, Lazar AJ, Thomas DM, Maki RG, Tap WD, Ali SM, Jin DX, Gounder MM, Agaram NP, Trabucco SE, Robinson V, Ferraro RA, Millis SZ, Krishnan A, Lee J, Attia S, Abida W, Drilon A, Chi P, Angelo SP, Dickson MA, Keohan ML, Kelly CM, Agulnik M, Chawla SP, Choy E, Chugh R, Meyer CF, Myer PA, Moore JL, Okimoto RA, Pollock RE,
Ravi V
, Singh AS, Somaiah N, Wagner AJ, Healey JH, Frampton GM, Venstrom JM, Ross JS, Ladanyi M, Singer S, Brennan MF, Schwartz GK,
Lazar AJ
, Thomas DM, Maki RG, Tap WD, Ali SM, Jin DX. Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma. Nat Commun. 2022 06 15; 13(1):3406.
PMID:
35705558
; PMCID:
PMC9200814
.
Citations:
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Vellano CP, White MG, Andrews MC, Chelvanambi M, Witt RG, Daniele JR, Titus M, McQuade JL, Conforti F, Burton EM, Lastrapes MJ, Ologun G, Cogdill AP, Morad G, Prieto P, Lazar AJ, Chu Y, Han G, Khan MAW, Helmink B,
Davies MA
,
Amaria RN
, Kovacs JJ,
Woodman SE
, Patel S,
Hwu P
, Peoples M, Lee JE, Cooper ZA, Zhu H, Gao G, Banerjee H, Lau M,
Gershenwald JE
, Lucci A, Keung EZ,
Ross MI
, Pala L, Pagan E, Segura RL, Liu Q, Borthwick MS, Lau E, Yates MS, Westin SN, Wani K, Tetzlaff MT, Haydu LE, Mahendra M, Ma X, Logothetis C, Kulstad Z, Johnson S, Hudgens CW, Feng N, Federico L, Long GV, Futreal PA,
Arur S
, Tawbi HA, Moran AE, Wang L, Heffernan TP, Marszalek JR, Wargo JA, Vellano CP,
White MG
, Andrews MC, Chelvanambi M, Witt RG, Daniele JR, Titus M,
McQuade JL
, Conforti F, Burton EM, Lastrapes MJ, Ologun G, Cogdill AP, Morad G, Prieto P,
Lazar AJ
, Chu Y, Han G, Khan MAW, Helmink B, Davies MA, Amaria RN, Kovacs JJ, Woodman SE, Patel S, Hwu P, Peoples M, Lee JE, Cooper ZA, Zhu H, Gao G, Banerjee H, Lau M, Gershenwald JE,
Lucci A
, Keung EZ, Ross MI, Pala L, Pagan E, Segura RL, Liu Q, Borthwick MS, Lau E,
Yates MS
,
Westin SN
, Wani K,
Tetzlaff MT
, Haydu LE, Mahendra M, Ma X,
Logothetis C
, Kulstad Z, Johnson S, Hudgens CW, Feng N, Federico L, Long GV, Futreal PA, Arur S,
Tawbi HA
, Moran AE, Wang L, Heffernan TP, Marszalek JR,
Wargo JA
, Conforti F, Pala L. Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy. Nature. 2022 06; 606(7915):797-803.
PMID:
35705814
.
Citations:
1
Fields:
Sci
Science
Translation:
Humans
Animals
Cloutier JM, Maloney NS, Wang WL, Lazar AJ, Cloutier JM, Maloney NS, Wang WL,
Lazar AJ
. Pigmented PRRX1::NCOA1-rearranged fibroblastic tumor: A rare morphologic variant of an emerging mesenchymal tumor. J Cutan Pathol. 2022 Sep; 49(9):802-807.
PMID:
35583270
.
Citations:
Fields:
Der
Dermatology
Pat
Pathology
Barnhill R, van Laere S, Vermeulen P, Roman-Roman S, Gardrat S, Alsafadi S, Tarin M, Champenois G, Nicolas A, Matet A, Cassoux N, Servois V, Rodrigues M, Scolyer R, Lazar A, Romano E, Piperno-Neumann S, Mariani P, Lugassy C, Barnhill R, van Laere S, Vermeulen P, Roman-Roman S, Gardrat S, Alsafadi S, Tarin M, Champenois G, Nicolas A, Matet A, Cassoux N, Servois V, Rodrigues M, Scolyer R,
Lazar A
, Romano E, Piperno-Neumann S, Mariani P, Lugassy C, Nicolas A, Matet A, Cassoux N. L1CAM and laminin vascular network: Association with the high-risk replacement histopathologic growth pattern in uveal melanoma liver metastases. Lab Invest. 2022 11; 102(11):1214-1224.
PMID:
35672380
.
Citations:
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Lamhamedi-Cherradi SE, Maitituoheti M, Menegaz BA, Krishnan S, Vetter AM, Camacho P, Wu CC, Beird HC, Porter RW, Ingram DR, Ramamoorthy V, Mohiuddin S, McCall D, Truong DD, Cuglievan B, Futreal PA, Velasco AR, Anvar NE, Utama B, Titus M, Lazar AJ, Wang WL, Rodriguez-Aguayo C,
Ratan R
, Livingston JA, Rai K, MacLeod AR, Daw NC, Hayes-Jordan A, Ludwig JA, Lamhamedi-Cherradi SE, Maitituoheti M, Menegaz BA, Krishnan S, Vetter AM,
Camacho P
, Wu CC, Beird HC, Porter RW, Ingram DR, Ramamoorthy V, Mohiuddin S, McCall D, Truong DD, Cuglievan B, Futreal PA, Velasco AR, Anvar NE, Utama B, Titus M,
Lazar AJ
, Wang WL, Rodriguez-Aguayo C, Ratan R, Livingston JA,
Rai K
, MacLeod AR, Daw NC,
Hayes-Jordan A
,
Ludwig JA
. The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma. Nat Commun. 2022 06 01; 13(1):3057.
PMID:
35650195
; PMCID:
PMC9160255
.
Citations:
1
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Wang Y, Tian X, Zhang W, Zhang Z, Lazcano R, Hingorani P, Roth ME, Gill JD, Harrison DJ, Xu Z, Jusu S,
Kannan S
, Wang J, Lazar AJ, Earley EJ, Erickson SW, Gelb T, Huxley P, Lahdenranta J, Mudd G, Kurmasheva RT, Houghton PJ, Smith MA, Kolb EA, Gorlick R, Wang Y, Tian X, Zhang W, Zhang Z, Lazcano R, Hingorani P, Roth ME, Gill JD, Harrison DJ, Xu Z, Jusu S, Kannan S, Wang J,
Lazar AJ
, Earley EJ, Erickson SW, Gelb T, Huxley P, Lahdenranta J, Mudd G, Kurmasheva RT, Houghton PJ, Smith MA, Kolb EA, Gorlick R. Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma. Mol Cancer Ther. 2022 06 01; 21(6):903-913.
PMID:
35312779
; PMCID:
PMC9167717
.
Citations:
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
Hailemichael Y
, Johnson DH, Abdel-Wahab N,
Foo WC
, Bentebibel SE, Daher M, Haymaker C, Wani K, Saberian C, Ogata D, Kim ST, Nurieva R, Lazar AJ, Abu-Sbeih H, Fa'ak F, Mathew A, Wang Y, Falohun A, Trinh V, Zobniw C, Spillson C,
Burks JK
, Awiwi M, Elsayes K, Soto LS, Melendez BD,
Davies MA
, Wargo J, Curry J, Yee C,
Lizee G
, Singh S,
Sharma P
, Allison JP,
Hwu P
, Ekmekcioglu S,
Diab A
, Hailemichael Y, Johnson DH, Abdel-Wahab N, Foo WC, Bentebibel SE, Daher M,
Haymaker C
, Wani K, Saberian C, Ogata D, Kim ST,
Nurieva R
,
Lazar AJ
, Abu-Sbeih H, Fa'ak F, Mathew A, Wang Y, Falohun A, Trinh V, Zobniw C, Spillson C, Burks JK, Awiwi M,
Elsayes K
, Soto LS, Melendez BD, Davies MA,
Wargo J
,
Curry J
,
Yee C
, Lizee G, Singh S, Sharma P,
Allison JP
, Hwu P,
Ekmekcioglu S
, Diab A. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 2022 05 09; 40(5):509-523.e6.
PMID:
35537412
; PMCID:
PMC9221568
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Zullow HJ, Sankar A, Ingram DR, Samé Guerra DD, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J,
Lazar AJ
, Kadoch C, Zullow HJ, Sankar A, Ingram DR, Samé Guerra DD, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J, Lazar AJ, Kadoch C, Sam? Guerra DD. The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma. Mol Cell. 2022 05 05; 82(9):1737-1750.e8.
PMID:
35390276
; PMCID:
PMC9465545
.
Citations:
1
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Animals
Cells
Wu CC, Beird HC, Lamhamedi-Cherradi SE, Soeung M, Ingram D, Truong DD, Porter RW, Krishnan S, Little L, Gumbs C, Zhang J, Titus M, Genovese G, Ludwig JA, Lazar AJ,
Hayes-Jordan A
, Futreal PA, Wu CC, Beird HC, Lamhamedi-Cherradi SE, Soeung M, Ingram D, Truong DD, Porter RW, Krishnan S, Little L, Gumbs C, Zhang J, Titus M,
Genovese G
,
Ludwig JA
,
Lazar AJ
, Hayes-Jordan A, Futreal PA. Multi-site desmoplastic small round cell tumors are genetically related and immune-cold. NPJ Precis Oncol. 2022 Apr 04; 6(1):21.
PMID:
35379887
; PMCID:
PMC8980094
.
Citations:
Nosé V, Lazar AJ, Nosé V,
Lazar AJ
, Nos? V. Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Familial Tumor Syndromes. Head Neck Pathol. 2022 Mar; 16(1):143-157.
PMID:
35312981
; PMCID:
PMC9018953
.
Citations:
1
Fields:
Neo
Neoplasms
Pat
Pathology
Translation:
Humans
Molina ER, Chim LK, Lamhamedi-Cherradi SE, Mohiuddin S, McCall D, Cuglievan B, Krishnan S, Porter RW, Ingram DR, Wang WL,
Lazar AJ
, Scott DW, Truong DD, Daw NC, Ludwig JA, Mikos AG, Molina ER, Chim LK, Lamhamedi-Cherradi SE, Mohiuddin S, McCall D, Cuglievan B, Krishnan S, Porter RW, Ingram DR, Wang WL, Lazar AJ, Scott DW, Truong DD, Daw NC,
Ludwig JA
, Mikos AG. Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients. Oncotarget. 2022; 13:521-533.
PMID:
35284040
; PMCID:
PMC8906536
.
Citations:
Fields:
Neo
Neoplasms
Bhalla AD, Landers SM, Singh AK, Landry JP, Yeagley MG, Myerson GSB, Delgado-Baez CB, Dunnand S, Nguyen T, Ma X, Bolshakov S, Menegaz BA, Lamhamedi-Cherradi SE, Mao X, Song X, Lazar AJ,
McCutcheon IE
,
Slopis JM
, Ludwig JA, Lev DC,
Rai K
,
Torres KE
, Bhalla AD, Landers SM, Singh AK, Landry JP, Yeagley MG, Myerson GSB, Delgado-Baez CB, Dunnand S, Nguyen T, Ma X, Bolshakov S, Menegaz BA, Lamhamedi-Cherradi SE, Mao X, Song X,
Lazar AJ
, McCutcheon IE, Slopis JM,
Ludwig JA
, Lev DC, Rai K, Torres KE. Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor. Lab Invest. 2022 06; 102(6):658-666.
PMID:
35228656
.
Citations:
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Animals
Nozzoli F, Lazar AJ, Castiglione F, Campanacci DA, Beltrami G, De Logu F, Caporalini C, Massi D, Roviello G, Nozzoli F,
Lazar AJ
, Castiglione F, Campanacci DA, Beltrami G, De Logu F, Caporalini C, Massi D, Roviello G. NTRK Fusions Detection in Paediatric Sarcomas to Expand the Morphological Spectrum and Clinical Relevance of Selected Entities. Pathol Oncol Res. 2022; 28:1610237.
PMID:
35295613
; PMCID:
PMC8919346
.
Citations:
1
Fields:
Neo
Neoplasms
Pat
Pathology
Translation:
Humans
Indave Ruiz BI, Armon S, Watanabe R, Uttley L, White VA, Lazar AJ, Cree IA, Indave Ruiz BI, Armon S, Watanabe R, Uttley L, White VA,
Lazar AJ
, Cree IA. Clonality, Mutation and Kaposi Sarcoma: A Systematic Review. Cancers (Basel). 2022 Feb 25; 14(5).
PMID:
35267506
; PMCID:
PMC8909603
.
Citations:
Nassif EF, Cope B, Traweek R, Witt RG,
Erstad DJ
, Scally CP, Thirasastr P, Zarzour MA,
Ludwig J
, Benjamin R,
Bishop AJ
,
Guadagnolo BA
, Ingram D, Wani K, Wang WL,
Lazar AJ
, Torres KE, Hunt KK,
Feig BW
, Roland CL,
Somaiah N
, Keung EZ, Nassif EF, Cope B, Traweek R, Witt RG, Erstad DJ, Scally CP, Thirasastr P,
Zarzour MA
, Ludwig J, Benjamin R, Bishop AJ, Guadagnolo BA, Ingram D, Wani K, Wang WL, Lazar AJ,
Torres KE
,
Hunt KK
, Feig BW,
Roland CL
, Somaiah N, Keung EZ. Real-world use of palbociclib monotherapy in retroperitoneal liposarcomas at a large volume sarcoma center. Int J Cancer. 2022 06 15; 150(12):2012-2024.
PMID:
35128664
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Wang J
, Wang WL, Sun H,
Huo L
, Wu Y, Chen H, Gan Q,
Meis JM
, Maloney N, Lazar AJ, Yoon EC, Albarracin CT,
Krishnamurthy S
,
Middleton LP
, Resetkova E, Yu W,
Tan D
, Lu W, Solis Soto LM, Wang S, Wistuba II, Parwani AV, Prieto VG, Sahin AA, Li Z, Ding Q, Wang J, Wang WL, Sun H, Huo L, Wu Y, Chen H, Gan Q, Meis JM, Maloney N,
Lazar AJ
, Yoon EC,
Albarracin CT
, Krishnamurthy S, Middleton LP,
Resetkova E
, Yu W, Tan D, Lu W, Solis Soto LM, Wang S,
Wistuba II
, Parwani AV,
Prieto VG
,
Sahin AA
, Li Z, Ding Q. Expression of TRPS1 in phyllodes tumor and sarcoma of the breast. Hum Pathol. 2022 03; 121:73-80.
PMID:
35063444
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Bill KLJ, Garnett J, Meaux I, Ma X, Creighton CJ, Bolshakov S, Barriere C, Debussche L, Lazar AJ, Prudner BC, Casadei L, Braggio D, Lopez G, Zewdu A, Bid H, Dina L, Pollock RE, Bill KLJ, Garnett J, Meaux I, Ma X,
Creighton CJ
, Bolshakov S, Barriere C, Debussche L,
Lazar AJ
, Prudner BC, Casadei L, Braggio D, Lopez G, Zewdu A, Bid H, Dina L, Pollock RE. Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma. Clin Cancer Res. 2022 Jan 15; 28(2):431.
PMID:
35045964
.
Citations:
Fields:
Neo
Neoplasms
Spencer CN,
McQuade JL
, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X, White MG, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, Andrews MC, Rodrigues RR, Morgun A, Kim YS, Roszik J, Hoffman KL, Zheng J, Zhou Y, Medik YB, Kahn LM, Johnson S, Hudgens CW, Wani K, Gaudreau PO, Harris AL, Jamal MA, Baruch EN, Perez-Guijarro E, Day CP, Merlino G, Pazdrak B, Lochmann BS, Szczepaniak-Sloane RA, Arora R, Anderson J, Zobniw CM, Posada E, Sirmans E, Simon J, Haydu LE, Burton EM, Wang L, Dang M, Clise-Dwyer K, Schneider S, Chapman T, Anang NAS, Duncan S, Toker J, Malke JC, Glitza IC,
Amaria RN
,
Tawbi HA
,
Diab A
, Wong MK,
Patel SP
,
Woodman SE
,
Davies MA
,
Ross MI
,
Gershenwald JE
, Lee JE,
Hwu P
,
Jensen V
, Samuels Y, Straussman R, Ajami NJ, Nelson KC,
Nezi L
,
Petrosino JF
, Futreal PA, Lazar AJ, Hu J, Jenq RR, Tetzlaff MT, Yan Y, Garrett WS, Huttenhower C,
Sharma P
,
Watowich SS
,
Allison JP
,
Cohen L
, Trinchieri G, Daniel CR,
Wargo JA
, Spencer CN, McQuade JL, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X,
White MG
, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, Andrews MC, Rodrigues RR, Morgun A, Kim YS, Roszik J, Hoffman KL, Zheng J, Zhou Y, Medik YB, Kahn LM, Johnson S, Hudgens CW, Wani K, Gaudreau PO, Harris AL, Jamal MA, Baruch EN, Perez-Guijarro E, Day CP, Merlino G, Pazdrak B, Lochmann BS, Szczepaniak-Sloane RA, Arora R, Anderson J, Zobniw CM, Posada E, Sirmans E, Simon J, Haydu LE, Burton EM, Wang L, Dang M, Clise-Dwyer K, Schneider S, Chapman T, Anang NAS, Duncan S, Toker J, Malke JC,
Glitza IC
, Amaria RN, Tawbi HA, Diab A, Wong MK, Patel SP, Woodman SE, Davies MA, Ross MI, Gershenwald JE, Lee JE, Hwu P, Jensen V, Samuels Y, Straussman R, Ajami NJ, Nelson KC, Nezi L, Petrosino JF, Futreal PA,
Lazar AJ
, Hu J, Jenq RR,
Tetzlaff MT
, Yan Y, Garrett WS, Huttenhower C, Sharma P, Watowich SS, Allison JP, Cohen L, Trinchieri G, Daniel CR, Wargo JA. Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response. Science. 2021 Dec 24; 374(6575):1632-1640.
PMID:
34941392
; PMCID:
PMC8970537
.
Citations:
31
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Pfister SM, Reyes-Múgica M, Chan JKC, Hasle H,
Lazar AJ
, Rossi S, Ferrari A, Jarzembowski JA, Pritchard-Jones K, Hill DA, Jacques TS, Wesseling P, López Terrada DH, von Deimling A, Kratz CP, Cree IA, Alaggio R, Pfister SM, Reyes-Múgica M, Chan JKC, Hasle H, Lazar AJ, Rossi S, Ferrari A, Jarzembowski JA, Pritchard-Jones K, Hill DA, Jacques TS, Wesseling P, López Terrada DH, von Deimling A, Kratz CP, Cree IA, Alaggio R, Reyes-M?gica M, Rossi S, Wesseling P, L?pez Terrada DH, Alaggio R. A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era. Cancer Discov. 2022 02; 12(2):331-355.
PMID:
34921008
; PMCID:
PMC9401511
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Benton S, Zhao J, Zhang B, Bahrami A, Barnhill RL, Busam K, Cerroni L, Cook MG, de la Fouchardière A, Elder DE, Johansson I, Landman G,
Lazar A
, LeBoit P, Lowe L, Massi D, Duncan LM, Messina J, Mihic-Probst D, Mihm MC, Piepkorn MW, Schmidt B, Scolyer RA, Shea CR,
Tetzlaff MT
, Tron VA, Xu X, Yeh I, Yun SJ, Zembowicz A, Gerami P, Benton S, Zhao J, Zhang B, Bahrami A, Barnhill RL, Busam K, Cerroni L, Cook MG, de la Fouchardière A, Elder DE, Johansson I, Landman G, Lazar A, LeBoit P, Lowe L, Massi D, Duncan LM, Messina J, Mihic-Probst D, Mihm MC, Piepkorn MW, Schmidt B, Scolyer RA, Shea CR, Tetzlaff MT, Tron VA, Xu X, Yeh I, Yun SJ, Zembowicz A, Gerami P, de la Fouchardi?re A, Landman G. Impact of Next-generation Sequencing on Interobserver Agreement and Diagnosis of Spitzoid Neoplasms. Am J Surg Pathol. 2021 12 01; 45(12):1597-1605.
PMID:
34757982
.
Citations:
2
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
White MG
, Szczepaniak Sloane R, Witt RG, Reuben A, Gaudreau PO, Andrews MC, Feng N, Johnson S, Class CA, Bristow C, Wani K, Hudgens C,
Nezi L
, Manzo T, De Macedo MP, Hu J, Davis R, Jiang H, Prieto P, Burton E,
Hwu P
,
Tawbi H
, Gershenwald J, Lazar AJ,
Tetzlaff MT
, Overwijk W, Woodman SE, Cooper ZA, Marszalek JR,
Davies MA
, Heffernan TP, Wargo JA, White MG, Szczepaniak Sloane R, Witt RG, Reuben A, Gaudreau PO, Andrews MC, Feng N, Johnson S, Class CA, Bristow C, Wani K, Hudgens C, Nezi L, Manzo T, De Macedo MP, Hu J, Davis R, Jiang H, Prieto P, Burton E, Hwu P, Tawbi H,
Gershenwald J
,
Lazar AJ
, Tetzlaff MT,
Overwijk W
,
Woodman SE
, Cooper ZA, Marszalek JR, Davies MA, Heffernan TP,
Wargo JA
. Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma. Oncoimmunology. 2021; 10(1):1992880.
PMID:
34777916
; PMCID:
PMC8583008
.
Citations:
2
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ramani NS, Patel KP, Routbort MJ, Alvarez H,
Broaddus R
, Chen H,
Rashid A
, Lazar A, Lucas FAS, Yao H, Manekia J, Dang H, Barkoh BA,
Medeiros LJ
, Luthra R, Roy-Chowdhuri S, Ramani NS,
Patel KP
,
Routbort MJ
, Alvarez H, Broaddus R, Chen H, Rashid A,
Lazar A
, Lucas FAS, Yao H, Manekia J, Dang H, Barkoh BA, Medeiros LJ,
Luthra R
, Roy-Chowdhuri S. Factors Impacting Clinically Relevant RNA Fusion Assays Using Next-Generation Sequencing. Arch Pathol Lab Med. 2021 11 01; 145(11):1405-1412.
PMID:
33493304
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Cells
Sloane RAS, White MG, Witt RG, Banerjee A,
Davies MA
, Han G, Burton E, Ajami N, Simon JM, Bernatchez C, Haydu LE, Tawbi HA,
Gershenwald JE
, Keung E,
Ross M
,
McQuade J
,
Amaria RN
, Wani K, Lazar AJ, Woodman SE, Wang L, Andrews MC,
Wargo JA
, Sloane RAS,
White MG
, Witt RG, Banerjee A, Davies MA, Han G, Burton E, Ajami N, Simon JM,
Bernatchez C
, Haydu LE,
Tawbi HA
, Gershenwald JE, Keung E, Ross M, McQuade J, Amaria RN, Wani K,
Lazar AJ
,
Woodman SE
, Wang L, Andrews MC, Wargo JA. Identification of MicroRNA-mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes. Cancers (Basel). 2021 Oct 22; 13(21).
PMID:
34771465
; PMCID:
PMC8582574
.
Citations:
Marx A, Chan JKC, Chalabreysse L, Dacic S, Detterbeck F, French CA, Hornick JL, Inagaki H, Jain D,
Lazar AJ
, Marino M, Marom EM, Moreira AL, Nicholson AG, Noguchi M, Nonaka D, Papotti MG, Porubsky S, Sholl LM, Tateyama H, Thomas de Montpréville V, Travis WD, Rajan A, Roden AC, Ströbel P, Marx A, Chan JKC, Chalabreysse L, Dacic S, Detterbeck F, French CA, Hornick JL, Inagaki H, Jain D, Lazar AJ, Marino M, Marom EM, Moreira AL, Nicholson AG, Noguchi M, Nonaka D, Papotti MG, Porubsky S, Sholl LM, Tateyama H, Thomas de Montpréville V, Travis WD, Rajan A, Roden AC, Ströbel P, Thomas de Montpr?ville V, Str?bel P. The 2021 WHO Classification of Tumors of the Thymus and Mediastinum: What Is New in Thymic Epithelial, Germ Cell, and Mesenchymal Tumors? J Thorac Oncol. 2022 02; 17(2):200-213.
PMID:
34695605
.
Citations:
6
Fields:
Neo
Neoplasms
Pul
Pulmonary Medicine
Translation:
Humans
Cells
Fung MA, Vidal CI, Armbrecht EA, Andea AA, Cassarino DS, Comfere NI, Emanuel PO, Ferringer T, Hristov AC, Kim J, Lauer SR, Linos K, Missall TA, Motaparthi K, Novoa RA, Patel R, Shalin SC, Sundram U, Calame A, Bennett DD, Duncan LM, Elston DM, Hosler GA, Hurley YM,
Lazar AJ
, Lowe L, Messina J, Myles J, Plaza JA, Prieto VG, Reddy V, Schaffer A, Subtil A, AUC Committee Members, Fung MA, Vidal CI, Armbrecht EA, Andea AA, Cassarino DS, Comfere NI, Emanuel PO, Ferringer T, Hristov AC, Kim J, Lauer SR, Linos K, Missall TA, Motaparthi K, Novoa RA, Patel R, Shalin SC, Sundram U, Rating Panel, Calame A, Bennett DD, Duncan LM, Elston DM, Hosler GA, Hurley YM, Lazar AJ, Lowe L, Messina J, Myles J, Plaza JA,
Prieto VG
, Reddy V, Schaffer A, Subtil A, Schaffer A. Appropriate use criteria for ancillary diagnostic testing in dermatopathology: New recommendations for 11 tests and 220 clinical scenarios from the American Society of Dermatopathology Appropriate Use Criteria Committee. J Cutan Pathol. 2022 Mar; 49(3):231-245.
PMID:
34536035
.
Citations:
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Vega DM, Yee LM, McShane LM, Williams PM, Chen L, Vilimas T, Fabrizio D, Funari V, Newberg J, Bruce LK, Chen SJ, Baden J, Carl Barrett J, Beer P, Butler M, Cheng JH, Conroy J, Cyanam D, Eyring K, Garcia E, Green G, Gregersen VR, Hellmann MD, Keefer LA, Lasiter L,
Lazar AJ
, Li MC, MacConaill LE, Meier K, Mellert H, Pabla S, Pallavajjalla A, Pestano G, Salgado R, Samara R, Sokol ES, Stafford P, Budczies J, Stenzinger A, Tom W, Valkenburg KC, Wang XZ, Weigman V, Xie M, Xie Q, Zehir A, Zhao C, Zhao Y, Stewart MD, Allen J, Vega DM, Yee LM, McShane LM, Williams PM, Chen L, Vilimas T, Fabrizio D, Funari V, Newberg J, Bruce LK, Chen SJ, Baden J, Carl Barrett J, Beer P, Butler M, Cheng JH, Conroy J, Cyanam D, Eyring K, Garcia E, Green G, Gregersen VR, Hellmann MD, Keefer LA, Lasiter L, Lazar AJ, Li MC, MacConaill LE, Meier K, Mellert H, Pabla S, Pallavajjalla A, Pestano G, Salgado R, Samara R, Sokol ES, Stafford P, Budczies J, Stenzinger A, Tom W, Valkenburg KC, Wang XZ, Weigman V, Xie M, Xie Q, Zehir A, Zhao C, Zhao Y, Stewart MD, Allen J, TMB Consortium. Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project. Ann Oncol. 2021 12; 32(12):1626-1636.
PMID:
34606929
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Panza E, Ozenberger BB, Straessler KM, Barrott JJ, Li L, Wang Y, Xie M, Boulet A, Titen SW, Mason CC,
Lazar AJ
, Ding L, Capecchi MR, Jones KB, Panza E, Ozenberger BB, Straessler KM, Barrott JJ, Li L, Wang Y, Xie M, Boulet A, Titen SW, Mason CC, Lazar AJ, Ding L, Capecchi MR, Jones KB. The clear cell sarcoma functional genomic landscape. J Clin Invest. 2021 08 02; 131(15).
PMID:
34156976
; PMCID:
PMC8321568
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Kochat V, Raman AT, Landers SM, Tang M, Schulz J, Terranova C, Landry JP, Bhalla AD, Beird HC, Wu CC, Jiang Y, Mao X, Lazcano R, Gite S, Ingram DR, Yi M, Zhang J, Keung EZ, Scally CP, Roland CL, Hunt KK, Feig BW, Futreal PA,
Hwu P
, Wang WL, Lazar AJ,
Slopis JM
, Wilson-Robles H, Wiener DJ,
McCutcheon IE
, Wustefeld-Janssens B, Rai K, Torres KE, Kochat V, Raman AT, Landers SM, Tang M, Schulz J, Terranova C, Landry JP, Bhalla AD, Beird HC, Wu CC, Jiang Y, Mao X, Lazcano R, Gite S, Ingram DR, Yi M, Zhang J, Keung EZ, Scally CP,
Roland CL
,
Hunt KK
,
Feig BW
, Futreal PA, Hwu P, Wang WL,
Lazar AJ
, Slopis JM, Wilson-Robles H, Wiener DJ, McCutcheon IE, Wustefeld-Janssens B,
Rai K
,
Torres KE
. Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state. Acta Neuropathol. 2021 09; 142(3):565-590.
PMID:
34283254
.
Citations:
2
Fields:
Neu
Neurology
Translation:
Humans
Animals
Cells
Terranova CJ, Tang M, Maitituoheti M, Raman AT, Ghosh AK, Schulz J, Amin SB, Orouji E, Tomczak K, Sarkar S, Oba J, Creasy C, Wu CJ, Khan S, Lazcano R, Wani K, Singh A, Barrodia P, Zhao D, Chen K, Haydu LE, Wang WL, Lazar AJ, Woodman SE,
Bernatchez C
,
Rai K
, Terranova CJ, Tang M, Maitituoheti M, Raman AT, Ghosh AK, Schulz J, Amin SB, Orouji E, Tomczak K, Sarkar S, Oba J, Creasy C, Wu CJ, Khan S, Lazcano R, Wani K, Singh A, Barrodia P, Zhao D, Chen K, Haydu LE, Wang WL,
Lazar AJ
,
Woodman SE
, Bernatchez C, Rai K. Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy. Cell Rep. 2021 07 20; 36(3):109410.
PMID:
34289358
; PMCID:
PMC8369408
.
Citations:
3
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Andrews MC, Duong CPM, Gopalakrishnan V, Iebba V, Chen WS, Derosa L, Khan MAW, Cogdill AP, White MG, Wong MC, Ferrere G, Fluckiger A, Roberti MP, Opolon P, Alou MT, Yonekura S, Roh W, Spencer CN, Curbelo IF, Vence L, Reuben A, Johnson S, Arora R, Morad G, Lastrapes M, Baruch EN, Little L, Gumbs C, Cooper ZA, Prieto PA, Wani K, Lazar AJ, Tetzlaff MT, Hudgens CW, Callahan MK, Adamow M, Postow MA, Ariyan CE, Gaudreau PO,
Nezi L
, Raoult D, Mihalcioiu C, Elkrief A, Pezo RC, Haydu LE, Simon JM, Tawbi HA, McQuade J,
Hwu P
,
Hwu WJ
,
Amaria RN
, Burton EM, Woodman SE, Watowich S,
Diab A
, Patel SP, Glitza IC, Wong MK, Zhao L, Zhang J, Ajami NJ,
Petrosino J
, Jenq RR,
Davies MA
,
Gershenwald JE
, Futreal PA,
Sharma P
,
Allison JP
, Routy B, Zitvogel L, Wargo JA, Andrews MC, Duong CPM, Gopalakrishnan V, Iebba V, Chen WS, Derosa L, Khan MAW, Cogdill AP,
White MG
, Wong MC, Ferrere G, Fluckiger A, Roberti MP, Opolon P, Alou MT, Yonekura S, Roh W, Spencer CN, Curbelo IF, Vence L, Reuben A, Johnson S, Arora R, Morad G, Lastrapes M, Baruch EN, Little L, Gumbs C, Cooper ZA, Prieto PA, Wani K,
Lazar AJ
,
Tetzlaff MT
, Hudgens CW, Callahan MK, Adamow M, Postow MA, Ariyan CE, Gaudreau PO, Nezi L, Raoult D, Mihalcioiu C, Elkrief A, Pezo RC, Haydu LE, Simon JM,
Tawbi HA
,
McQuade J
, Hwu P, Hwu WJ, Amaria RN, Burton EM,
Woodman SE
,
Watowich S
, Diab A,
Patel SP
,
Glitza IC
, Wong MK, Zhao L, Zhang J, Ajami NJ, Petrosino J, Jenq RR, Davies MA, Gershenwald JE, Futreal PA, Sharma P, Allison JP, Routy B, Zitvogel L,
Wargo JA
, Fluckiger A, Raoult D. Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade. Nat Med. 2021 08; 27(8):1432-1441.
PMID:
34239137
.
Citations:
39
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Patel RR, Lupo PJ,
Bishop AJ
,
Lin PP
, Delclos GL, Lazar AJ, Benjamin RS, Araujo DM, Patel RR,
Lupo PJ
, Bishop AJ, Lin PP, Delclos GL,
Lazar AJ
, Benjamin RS,
Araujo DM
. Synovial Sarcoma of the Hand and Foot: An Institutional Review. Am J Clin Oncol. 2021 07 01; 44(7):361-368.
PMID:
33927134
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cho WC, Wang WL, Milton DR, Ingram DR,
Nagarajan P
,
Curry JL
, Ivan D, Lazar AJ, Hwu WJ,
Prieto VG
, Torres-Cabala CA,
Aung PP
, Cho WC, Wang WL, Milton DR, Ingram DR, Nagarajan P, Curry JL,
Ivan D
,
Lazar AJ
,
Hwu WJ
, Prieto VG, Torres-Cabala CA, Aung PP, Milton DR. Telomerase Reverse Transcriptase Protein Expression Is More Frequent in Acral Lentiginous Melanoma Than in Other Types of Cutaneous Melanoma. Arch Pathol Lab Med. 2021 07 01; 145(7):842-850.
PMID:
33053175
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Cells
Leske H, Dalgleish R, Lazar AJ, Reifenberger G, Cree IA, Leske H, Dalgleish R,
Lazar AJ
, Reifenberger G, Cree IA, Reifenberger G. A common classification framework for histone sequence alterations in tumours: an expert consensus proposal. J Pathol. 2021 06; 254(2):109-120.
PMID:
33779999
.
Citations:
2
Fields:
Pat
Pathology
Translation:
Humans
Tolwani A, Matusiak M, Bui N, Forgó E, Varma S, Baratto L, Iagaru A, Lazar AJ, van de Rijn M, Przybyl J, Tolwani A, Matusiak M, Bui N, Forgó E, Varma S, Baratto L, Iagaru A,
Lazar AJ
, van de Rijn M, Przybyl J, Forg? E. Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma. NPJ Genom Med. 2021 May 03; 6(1):30.
PMID:
33941787
; PMCID:
PMC8093268
.
Citations:
1
Wagner MJ, Lyons YA, Siedel JH, Dood R, Nagaraja AS, Haemmerle M, Mangala LS, Chanana P,
Lazar AJ
, Wang WL,
Ravi V
, Holland EC, Sood AK, Wagner MJ, Lyons YA, Siedel JH, Dood R, Nagaraja AS, Haemmerle M,
Mangala LS
, Chanana P, Lazar AJ, Wang WL, Ravi V, Holland EC,
Sood AK
. Combined VEGFR and MAPK pathway inhibition in angiosarcoma. Sci Rep. 2021 04 30; 11(1):9362.
PMID:
33931674
; PMCID:
PMC8087824
.
Citations:
3
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Schaefer IM, Lundberg MZ, Demicco EG, Przybyl J, Matusiak M, Chibon F, Ingram DR, Hornick JL, Wang WL, Bauer S, Baker LH, Lazar AJ, van de Rijn M, Mariño-Enríquez A, Fletcher JA, Schaefer IM, Lundberg MZ, Demicco EG, Przybyl J, Matusiak M, Chibon F, Ingram DR, Hornick JL, Wang WL, Bauer S, Baker LH,
Lazar AJ
, van de Rijn M, Mariño-Enríquez A, Fletcher JA, Chibon F, Mari?o-Enr?quez A. Relationships between highly recurrent tumor suppressor alterations in 489 leiomyosarcomas. Cancer. 2021 08 01; 127(15):2666-2673.
PMID:
33788262
; PMCID:
PMC8277678
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Warmke LM, Tinkham EG, Ingram DR,
Lazar AJ
, Panse G, Wang WL, Warmke LM, Tinkham EG, Ingram DR, Lazar AJ, Panse G, Wang WL. INSM1 Expression in Angiosarcoma. Am J Clin Pathol. 2021 03 15; 155(4):575-580.
PMID:
33210141
.
Citations:
2
Fields:
Pat
Pathology
Translation:
Humans
Landry JP, Schertz KL, Chiang YJ, Bhalla AD, Yi M, Keung EZ, Scally CP,
Feig BW
, Hunt KK, Roland CL, Guadagnolo A,
Bishop AJ
, Lazar AJ, Slopis JM,
McCutcheon IE
,
Torres KE
, Landry JP, Schertz KL, Chiang YJ, Bhalla AD, Yi M, Keung EZ, Scally CP, Feig BW,
Hunt KK
,
Roland CL
, Guadagnolo A, Bishop AJ,
Lazar AJ
,
Slopis JM
, McCutcheon IE, Torres KE. Comparison of Cancer Prevalence in Patients With Neurofibromatosis Type 1 at an Academic Cancer Center vs in the General Population From 1985 to 2020. JAMA Netw Open. 2021 03 01; 4(3):e210945.
PMID:
33734413
; PMCID:
PMC7974640
.
Citations:
8
Fields:
Med
Medicine (General)
Translation:
Humans
Ding Z, Ogata D, Roszik J, Qin Y, Kim SH, Tetzlaff MT, Lazar AJ, Davies MA, Ekmekcioglu S,
Grimm EA
, Ding Z, Ogata D, Roszik J, Qin Y, Kim SH,
Tetzlaff MT
,
Lazar AJ
,
Davies MA
,
Ekmekcioglu S
, Grimm EA. iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation. Front Oncol. 2021; 11:631766.
PMID:
33643925
; PMCID:
PMC7907506
.
Citations:
2
Rathore R, Caldwell KE, Schutt C, Brashears CB, Prudner BC, Ehrhardt WR, Leung CH, Lin H, Daw NC, Beird HC, Giles A, Wang WL,
Lazar AJ
, Chrisinger JSA, Livingston JA, Van Tine BA, Rathore R, Caldwell KE, Schutt C, Brashears CB, Prudner BC, Ehrhardt WR, Leung CH, Lin H, Daw NC, Beird HC, Giles A, Wang WL, Lazar AJ, Chrisinger JSA, Livingston JA, Van Tine BA. Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma. Cell Rep. 2021 01 26; 34(4):108678.
PMID:
33503424
; PMCID:
PMC8552368
.
Citations:
9
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Fischer GM, Guerrieri RA,
Hu Q
, Joon AY, Kumar S, Haydu LE, McQuade JL, Vashisht Gopal YN, Knighton B, Deng W, Hudgens CW, Lazar AJ,
Tetzlaff MT
,
Davies MA
, Fischer GM, Guerrieri RA, Hu Q, Joon AY, Kumar S, Haydu LE,
McQuade JL
, Vashisht Gopal YN, Knighton B, Deng W, Hudgens CW,
Lazar AJ
, Tetzlaff MT, Davies MA. Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdaa177.
PMID:
33575655
; PMCID:
PMC7865080
.
Citations:
2
Wang R, Dang M, Harada K, Han G, Wang F, Pool Pizzi M, Zhao M, Tatlonghari G, Zhang S, Hao D, Lu Y, Zhao S,
Badgwell BD
, Blum Murphy M, Shanbhag N, Estrella JS, Roy-Chowdhuri S, Abdelhakeem AAF, Wang Y, Peng G, Hanash S,
Calin GA
, Song X, Chu Y, Zhang J, Li M, Chen K,
Lazar AJ
, Futreal A, Song S,
Ajani JA
, Wang L, Wang R, Dang M, Harada K, Han G, Wang F, Pool Pizzi M, Zhao M, Tatlonghari G, Zhang S, Hao D, Lu Y, Zhao S, Badgwell BD,
Blum Murphy M
, Shanbhag N,
Estrella JS
, Roy-Chowdhuri S, Abdelhakeem AAF, Wang Y, Peng G,
Hanash S
, Calin GA, Song X, Chu Y, Zhang J, Li M, Chen K, Lazar AJ,
Futreal A
, Song S, Ajani JA, Wang L. Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma. Nat Med. 2021 01; 27(1):141-151.
PMID:
33398161
; PMCID:
PMC8074162
.
Citations:
30
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Boyce-Fappiano D,
Guadagnolo BA
, Ratan R, Wang WL, Wagner MJ,
Patel S
,
Livingston JA
, Lin PP, Diao K, Mitra D, Farooqi A,
Lazar AJ
,
Roland CL
, Bishop AJ, Boyce-Fappiano D, Guadagnolo BA,
Ratan R
, Wang WL, Wagner MJ, Patel S, Livingston JA,
Lin PP
, Diao K, Mitra D, Farooqi A, Lazar AJ, Roland CL,
Bishop AJ
. Evaluating the Soft Tissue Sarcoma Paradigm for the Local Management of Extraskeletal Ewing Sarcoma. Oncologist. 2021 03; 26(3):250-260.
PMID:
33289298
; PMCID:
PMC7930399
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Washington MK, Goldberg RM, Chang GJ, Limburg P, Lam AK, Salto-Tellez M, Arends MJ, Nagtegaal ID, Klimstra DS,
Rugge M
, Schirmacher P,
Lazar AJ
, Odze RD, Carneiro F, Fukayama M, Cree IA, Washington MK, Goldberg RM, Chang GJ, Limburg P, Lam AK, Salto-Tellez M, Arends MJ, Nagtegaal ID, Klimstra DS, Rugge M, Schirmacher P, Lazar AJ, Odze RD, Carneiro F, Fukayama M, Cree IA, WHO Classification of Tumours Editorial Board. Diagnosis of digestive system tumours. Int J Cancer. 2021 03 01; 148(5):1040-1050.
PMID:
32674220
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Qin Y, Bollin K, de Macedo MP, Carapeto F, Kim KB, Roszik J, Wani KM, Reuben A, Reddy ST, Williams MD,
Tetzlaff MT
, Wang WL,
Gombos DS
, Esmaeli B,
Lazar AJ
,
Hwu P
,
Patel SP
, Qin Y, Bollin K, de Macedo MP, Carapeto F, Kim KB, Roszik J, Wani KM, Reuben A, Reddy ST, Williams MD, Tetzlaff MT, Wang WL, Gombos DS,
Esmaeli B
, Lazar AJ, Hwu P, Patel SP. Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy. J Immunother Cancer. 2020 11; 8(2).
PMID:
33203661
; PMCID:
PMC7674090
.
Citations:
16
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Ramani NS, Chen H,
Broaddus RR
, Lazar AJ,
Luthra R
, Medeiros LJ,
Patel KP
, Rashid A,
Routbort MJ
, Stewart J, Tang Z, Bassett R, Manekia J, Barkoh BA, Dang H, Roy-Chowdhuri S, Ramani NS, Chen H, Broaddus RR,
Lazar AJ
, Luthra R,
Medeiros LJ
, Patel KP,
Rashid A
, Routbort MJ, Stewart J,
Tang Z
, Bassett R, Manekia J, Barkoh BA, Dang H, Roy-Chowdhuri S. Utilization of cytology smears improves success rates of RNA-based next-generation sequencing gene fusion assays for clinically relevant predictive biomarkers. Cancer Cytopathol. 2021 05; 129(5):374-382.
PMID:
33119213
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Landers SM, Bhalla AD, Ma X, Lusby K, Ingram D, Al Sannaa G, Wang WL, Lazar AJ, Torres KE, Landers SM, Bhalla AD, Ma X, Lusby K, Ingram D, Al Sannaa G, Wang WL,
Lazar AJ
,
Torres KE
. AXL Inhibition Enhances MEK Inhibitor Sensitivity in Malignant Peripheral Nerve Sheath Tumors. J Cancer Sci Clin Ther. 2020; 4(4):511-525.
PMID:
33283192
; PMCID:
PMC7717506
.
Citations:
Maitituoheti M, Keung EZ, Tang M, Yan L, Alam H, Han G, Singh AK, Raman AT, Terranova C, Sarkar S, Orouji E, Amin SB, Sharma S, Williams M, Samant NS, Dhamdhere M, Zheng N, Shah T, Shah A, Axelrad JB, Anvar NE, Lin YH, Jiang S, Chang EQ, Ingram DR, Wang WL,
Lazar A
, Lee MG,
Muller F
, Wang L, Ying H, Rai K, Maitituoheti M, Keung EZ, Tang M, Yan L, Alam H, Han G, Singh AK, Raman AT, Terranova C, Sarkar S, Orouji E, Amin SB, Sharma S, Williams M, Samant NS, Dhamdhere M, Zheng N, Shah T, Shah A, Axelrad JB, Anvar NE, Lin YH, Jiang S, Chang EQ, Ingram DR, Wang WL, Lazar A, Lee MG, Muller F, Wang L,
Ying H
,
Rai K
. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma. Cell Rep. 2020 10 20; 33(3):108293.
PMID:
33086062
; PMCID:
PMC7649750
.
Citations:
7
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Cree IA, Indave Ruiz BI, Zavadil J, McKay J, Olivier M, Kozlakidis Z,
Lazar AJ
, Hyde C, Holdenrieder S, Hastings R, Rajpoot N, de la Fouchardiere A, Rous B, Zenklusen JC, Normanno N, Schilsky RL, Cree IA, Indave Ruiz BI, Zavadil J, McKay J, Olivier M, Kozlakidis Z, Lazar AJ, Hyde C, Holdenrieder S, Hastings R, Rajpoot N, de la Fouchardiere A, Rous B, Zenklusen JC, Normanno N, Schilsky RL, IC3R participants, de la Fouchardiere A. The International Collaboration for Cancer Classification and Research. Int J Cancer. 2021 02 01; 148(3):560-571.
PMID:
32818326
; PMCID:
PMC7756795
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Panse G, Mito JK, Ingram DR, Wani K, Khan S,
Lazar AJ
, Doyle LA, Wang WL, Panse G, Mito JK, Ingram DR, Wani K, Khan S, Lazar AJ, Doyle LA, Wang WL. Radiation-associated sarcomas other than malignant peripheral nerve sheath tumours demonstrate loss of histone H3K27 trimethylation?. Histopathology. 2021 Jan; 78(2):321-326.
PMID:
32735735
.
Citations:
4
Fields:
Pat
Pathology
Translation:
Humans
Cells
Fischer GM, Carapeto FCL, Joon AY, Haydu LE, Chen H, Wang F, Van Arnam JS, McQuade JL, Wani K, Kirkwood JM, Thompson JF,
Tetzlaff MT
, Lazar AJ, Tawbi HA,
Gershenwald JE
, Scolyer RA, Long GV, Davies MA, Fischer GM, Carapeto FCL, Joon AY, Haydu LE, Chen H, Wang F, Van Arnam JS,
McQuade JL
, Wani K,
Kirkwood JM
, Thompson JF, Tetzlaff MT,
Lazar AJ
,
Tawbi HA
, Gershenwald JE, Scolyer RA, Long GV,
Davies MA
. Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker. Cancer Med. 2020 11; 9(22):8650-8661.
PMID:
33016647
; PMCID:
PMC7666738
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Demetri GD, Antonescu CR, Bjerkehagen B, Bovée JVMG, Boye K, Chacón M, Dei Tos AP, Desai J, Fletcher JA, Gelderblom H, George S, Gronchi A, Haas RL, Hindi N, Hohenberger P, Joensuu H, Jones RL, Judson I, Kang YK, Kawai A, Lazar AJ, Le Cesne A, Maestro R, Maki RG, Martín J, Patel S, Penault-Llorca F, Premanand Raut C, Rutkowski P, Safwat A, Sbaraglia M, Schaefer IM, Shen L, Serrano C, Schöffski P, Stacchiotti S, Sundby Hall K, Tap WD, Thomas DM, Trent J, Valverde C, van der Graaf WTA, von Mehren M, Wagner A, Wardelmann E, Naito Y, Zalcberg J, Blay JY, Demetri GD, Antonescu CR, Bjerkehagen B, Bovée JVMG, Boye K, Chacón M, Dei Tos AP, Desai J, Fletcher JA, Gelderblom H, George S, Gronchi A, Haas RL, Hindi N, Hohenberger P, Joensuu H, Jones RL, Judson I, Kang YK, Kawai A,
Lazar AJ
, Le Cesne A, Maestro R, Maki RG, Martín J, Patel S, Penault-Llorca F, Premanand Raut C, Rutkowski P, Safwat A, Sbaraglia M, Schaefer IM, Shen L, Serrano C, Schöffski P, Stacchiotti S, Sundby Hall K, Tap WD, Thomas DM, Trent J, Valverde C, van der Graaf WTA, von Mehren M, Wagner A, Wardelmann E, Naito Y, Zalcberg J, Blay JY, Bov?e JVMG, Chac?n M, Mart?n J, Sch?ffski P, Wardelmann E, Blay JY. Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network. Ann Oncol. 2020 11; 31(11):1506-1517.
PMID:
32891793
; PMCID:
PMC7985805
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Tan PH, Ellis I, Allison K, Brogi E, Fox SB, Lakhani S,
Lazar AJ
, Morris EA,
Sahin A
, Salgado R, Sapino A, Sasano H, Schnitt S, Sotiriou C, van Diest P, White VA, Lokuhetty D, Cree IA, Tan PH, Ellis I, Allison K, Brogi E, Fox SB, Lakhani S, Lazar AJ, Morris EA, Sahin A, Salgado R, Sapino A, Sasano H, Schnitt S, Sotiriou C, van Diest P, White VA, Lokuhetty D, Cree IA, WHO Classification of Tumours Editorial Board, Sotiriou C. The 2019 World Health Organization classification of tumours of the breast. Histopathology. 2020 08; 77(2):181-185.
PMID:
32056259
.
Citations:
84
Fields:
Pat
Pathology
Translation:
Humans
Amin HM
, Morani AC, Daw NC, Lamhamedi-Cherradi SE,
Subbiah V
, Menegaz BA, Vishwamitra D,
Eskandari G
, George B, Benjamin RS,
Patel S
, Song J, Lazar AJ, Wang WL, Kurzrock R, Pappo A, Anderson PM, Schwartz GK,
Araujo D
, Cuglievan B,
Ratan R
, McCall D, Mohiuddin S, Livingston JA, Molina ER, Naing A, Ludwig JA, Amin HM,
Morani AC
, Daw NC, Lamhamedi-Cherradi SE, Subbiah V, Menegaz BA, Vishwamitra D, Eskandari G, George B, Benjamin RS, Patel S, Song J,
Lazar AJ
, Wang WL, Kurzrock R, Pappo A, Anderson PM, Schwartz GK, Araujo D, Cuglievan B, Ratan R, McCall D, Mohiuddin S,
Livingston JA
, Molina ER,
Naing A
,
Ludwig JA
. IGF-1R/mTOR Targeted Therapy for Ewing Sarcoma: A Meta-Analysis of Five IGF-1R-Related Trials Matched to Proteomic and Radiologic Predictive Biomarkers. Cancers (Basel). 2020 Jul 02; 12(7).
PMID:
32630797
; PMCID:
PMC7408058
.
Citations:
10
Huang J, Sachdeva M, Xu E, Robinson TJ, Luo L, Ma Y, Williams NT, Lopez O, Cervia LD, Yuan F, Qin X, Zhang D, Owzar K, Gokgoz N, Seto A, Okada T, Singer S, Andrulis IL, Wunder JS,
Lazar AJ
, Rubin BP, Pipho K, Mello SS, Giudice J, Kirsch DG, Huang J, Sachdeva M, Xu E, Robinson TJ, Luo L, Ma Y, Williams NT, Lopez O, Cervia LD, Yuan F, Qin X, Zhang D, Owzar K, Gokgoz N, Seto A, Okada T, Singer S, Andrulis IL, Wunder JS, Lazar AJ, Rubin BP, Pipho K, Mello SS, Giudice J, Kirsch DG. The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways. Mol Cancer Res. 2020 10; 18(10):1534-1544.
PMID:
32561656
; PMCID:
PMC7541426
.
Citations:
5
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Amgad M, Stovgaard ES, Balslev E, Thagaard J, Chen W, Dudgeon S, Sharma A, Kerner JK, Denkert C, Yuan Y, AbdulJabbar K, Wienert S, Savas P, Voorwerk L, Beck AH, Madabhushi A, Hartman J, Sebastian MM, Horlings HM, Hudecek J, Ciompi F, Moore DA, Singh R, Roblin E, Balancin ML, Mathieu MC, Lennerz JK, Kirtani P, Chen IC, Braybrooke JP, Pruneri G, Demaria S, Adams S, Schnitt SJ, Lakhani SR, Rojo F, Comerma L, Badve SS, Khojasteh M, Symmans WF, Sotiriou C, Gonzalez-Ericsson P, Pogue-Geile KL, Kim RS, Rimm DL, Viale G, Hewitt SM, Bartlett JMS, Penault-Llorca F, Goel S, Lien HC, Loibl S, Kos Z, Loi S, Hanna MG, Michiels S, Kok M, Nielsen TO,
Lazar AJ
, Bago-Horvath Z, Kooreman LFS, van der Laak JAWM, Saltz J, Gallas BD, Kurkure U, Barnes M, Salgado R, Cooper LAD, Amgad M, Stovgaard ES, Balslev E, Thagaard J, Chen W, Dudgeon S, Sharma A, Kerner JK, Denkert C, Yuan Y, AbdulJabbar K, Wienert S, Savas P, Voorwerk L, Beck AH, Madabhushi A, Hartman J, Sebastian MM, Horlings HM, Hudecek J, Ciompi F, Moore DA, Singh R, Roblin E, Balancin ML, Mathieu MC, Lennerz JK, Kirtani P, Chen IC, Braybrooke JP, Pruneri G, Demaria S, Adams S, Schnitt SJ, Lakhani SR, Rojo F, Comerma L, Badve SS, Khojasteh M,
Symmans WF
, Sotiriou C, Gonzalez-Ericsson P, Pogue-Geile KL, Kim RS, Rimm DL, Viale G, Hewitt SM, Bartlett JMS, Penault-Llorca F, Goel S, Lien HC, Loibl S, Kos Z, Loi S, Hanna MG, Michiels S, Kok M, Nielsen TO, Lazar AJ, Bago-Horvath Z, Kooreman LFS, van der Laak JAWM, Saltz J, Gallas BD, Kurkure U, Barnes M, Salgado R, Cooper LAD, International Immuno-Oncology Biomarker Working Group, Denkert C, Wienert S, Roblin E, Balancin ML, Rojo F, Comerma L, Sotiriou C, Penault-Llorca F. Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group. NPJ Breast Cancer. 2020; 6:16.
PMID:
32411818
; PMCID:
PMC7217824
.
Citations:
27
Kos Z, Roblin E, Kim RS, Michiels S, Gallas BD, Chen W, van de Vijver KK, Goel S, Adams S, Demaria S, Viale G, Nielsen TO, Badve SS, Symmans WF, Sotiriou C, Rimm DL, Hewitt S, Denkert C, Loibl S, Luen SJ, Bartlett JMS, Savas P, Pruneri G, Dillon DA, Cheang MCU, Tutt A, Hall JA, Kok M, Horlings HM, Madabhushi A, van der Laak J, Ciompi F, Laenkholm AV, Bellolio E, Gruosso T, Fox SB, Araya JC, Floris G, Hudecek J, Voorwerk L, Beck AH, Kerner J, Larsimont D, Declercq S, Van den Eynden G, Pusztai L, Ehinger A, Yang W, AbdulJabbar K, Yuan Y, Singh R, Hiley C, Bakir MA,
Lazar AJ
, Naber S, Wienert S, Castillo M, Curigliano G, Dieci MV, André F, Swanton C, Reis-Filho J, Sparano J, Balslev E, Chen IC, Stovgaard EIS, Pogue-Geile K, Blenman KRM, Penault-Llorca F, Schnitt S, Lakhani SR, Vincent-Salomon A, Rojo F, Braybrooke JP, Hanna MG, Soler-Monsó MT, Bethmann D, Castaneda CA, Willard-Gallo K, Sharma A, Lien HC, Fineberg S, Thagaard J, Comerma L, Gonzalez-Ericsson P, Brogi E, Loi S, Saltz J, Klaushen F, Cooper L, Amgad M, Moore DA, Salgado R, Kos Z, Roblin E, Kim RS, Michiels S, Gallas BD, Chen W, van de Vijver KK, Goel S, Adams S, Demaria S, Viale G, Nielsen TO, Badve SS,
Symmans WF
, Sotiriou C, Rimm DL, Hewitt S, Denkert C, Loibl S, Luen SJ, Bartlett JMS, Savas P, Pruneri G, Dillon DA, Cheang MCU, Tutt A, Hall JA, Kok M, Horlings HM, Madabhushi A, van der Laak J, Ciompi F, Laenkholm AV, Bellolio E, Gruosso T, Fox SB, Araya JC, Floris G, Hudecek J, Voorwerk L, Beck AH, Kerner J, Larsimont D, Declercq S, Van den Eynden G, Pusztai L, Ehinger A, Yang W, AbdulJabbar K, Yuan Y, Singh R, Hiley C, Bakir MA, Lazar AJ, Naber S, Wienert S, Castillo M, Curigliano G, Dieci MV, André F, Swanton C, Reis-Filho J, Sparano J, Balslev E, Chen IC, Stovgaard EIS, Pogue-Geile K, Blenman KRM, Penault-Llorca F, Schnitt S, Lakhani SR, Vincent-Salomon A, Rojo F, Braybrooke JP, Hanna MG, Soler-Monsó MT, Bethmann D, Castaneda CA, Willard-Gallo K, Sharma A, Lien HC, Fineberg S, Thagaard J, Comerma L, Gonzalez-Ericsson P, Brogi E, Loi S, Saltz J, Klaushen F, Cooper L, Amgad M, Moore DA, Salgado R, International Immuno-Oncology Biomarker Working Group, Sotiriou C, Denkert C, Laenkholm AV, Bellolio E, Ehinger A, Wienert S, Andr? F, Penault-Llorca F, Vincent-Salomon A, Rojo F, Soler-Mons? MT, Willard-Gallo K, Thagaard J, Klaushen F. Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer. NPJ Breast Cancer. 2020; 6:17.
PMID:
32411819
; PMCID:
PMC7217863
.
Citations:
38
Carrot-Zhang J, Chambwe N, Damrauer JS, Knijnenburg TA, Robertson AG, Yau C, Zhou W, Berger AC, Huang KL, Newberg JY, Mashl RJ, Romanel A, Sayaman RW, Demichelis F, Felau I, Frampton GM, Han S, Hoadley KA, Kemal A, Laird PW, Lazar AJ, Le X, Oak N, Shen H, Wong CK, Zenklusen JC, Ziv E, Cherniack AD, Beroukhim R, Carrot-Zhang J, Chambwe N, Damrauer JS, Knijnenburg TA, Robertson AG, Yau C, Zhou W, Berger AC, Huang KL, Newberg JY, Mashl RJ, Romanel A, Sayaman RW, Demichelis F, Felau I, Frampton GM, Han S, Hoadley KA, Kemal A, Laird PW,
Lazar AJ
, Le X, Oak N, Shen H, Wong CK, Zenklusen JC, Ziv E, Cancer Genome Atlas Analysis Network, Cherniack AD, Beroukhim R. Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer. Cancer Cell. 2020 05 11; 37(5):639-654.e6.
PMID:
32396860
; PMCID:
PMC7328015
.
Citations:
56
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Bishop AJ
, Landry JP,
Roland CL
,
Ratan R
,
Feig BW
, Moon BS, Zarzour MA, Wang WL,
Lazar AJ
,
Lewis VO
,
Torres KE
,
Guadagnolo BA
, Bishop AJ, Landry JP, Roland CL, Ratan R, Feig BW,
Moon BS
,
Zarzour MA
, Wang WL, Lazar AJ, Lewis VO, Torres KE, Guadagnolo BA. Certain risk factors for patients with desmoid tumors warrant reconsideration of local therapy strategies. Cancer. 2020 07 15; 126(14):3265-3273.
PMID:
32343846
; PMCID:
PMC7748083
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Barnhill R, van Dam PJ, Vermeulen P, Champenois G, Nicolas A, Rawson RV, Wilmott JS, Thompson JF, Long GV, Cassoux N, Roman-Roman S, Busam KJ, Scolyer RA,
Lazar AJ
, Lugassy C, Barnhill R, van Dam PJ, Vermeulen P, Champenois G, Nicolas A, Rawson RV, Wilmott JS, Thompson JF, Long GV, Cassoux N, Roman-Roman S, Busam KJ, Scolyer RA, Lazar AJ, Lugassy C, Nicolas A, Cassoux N. Replacement and desmoplastic histopathological growth patterns in cutaneous melanoma liver metastases: frequency, characteristics, and robust prognostic value. J Pathol Clin Res. 2020 07; 6(3):195-206.
PMID:
32304183
; PMCID:
PMC7339161
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
Mitra A, Andrews MC, Roh W, De Macedo MP, Hudgens CW, Carapeto F, Singh S, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S, Ng KS, Schalck A, Sakellariou-Thompson DA, Chen E, Reddy SM, Spencer CN, Wiesnoski D, Little LD, Gumbs C, Cooper ZA, Burton EM,
Hwu P
, Davies MA, Zhang J,
Bernatchez C
,
Navin N
,
Sharma P
,
Allison JP
,
Wargo JA
,
Yee C
,
Tetzlaff MT
,
Hwu WJ
,
Lazar AJ
, Futreal PA, Mitra A, Andrews MC, Roh W, De Macedo MP, Hudgens CW, Carapeto F, Singh S, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S, Ng KS, Schalck A, Sakellariou-Thompson DA, Chen E, Reddy SM, Spencer CN, Wiesnoski D, Little LD, Gumbs C, Cooper ZA, Burton EM, Hwu P,
Davies MA
, Zhang J, Bernatchez C, Navin N, Sharma P, Allison JP, Wargo JA, Yee C, Tetzlaff MT, Hwu WJ, Lazar AJ, Futreal PA. Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nat Commun. 2020 04 15; 11(1):1839.
PMID:
32296058
; PMCID:
PMC7160105
.
Citations:
5
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Gonzalez-Ericsson PI, Stovgaard ES, Sua LF, Reisenbichler E, Kos Z, Carter JM, Michiels S, Le Quesne J, Nielsen TO, Laenkholm AV, Fox SB, Adam J, Bartlett JM, Rimm DL, Quinn C, Peeters D, Dieci MV, Vincent-Salomon A, Cree I, Hida AI, Balko JM, Haynes HR, Frahm I, Acosta-Haab G, Balancin M, Bellolio E, Yang W, Kirtani P, Sugie T, Ehinger A, Castaneda CA, Kok M, McArthur H, Siziopikou K, Badve S, Fineberg S, Gown A, Viale G, Schnitt SJ, Pruneri G, Penault-Llorca F, Hewitt S, Thompson EA, Allison KH, Symmans WF, Bellizzi AM, Brogi E, Moore DA, Larsimont D, Dillon DA, Lazar A, Lien H, Goetz MP, Broeckx G, El Bairi K, Harbeck N, Cimino-Mathews A, Sotiriou C, Adams S, Liu SW, Loibl S, Chen IC, Lakhani SR, Juco JW, Denkert C, Blackley EF, Demaria S, Leon-Ferre R, Gluz O, Zardavas D, Emancipator K, Ely S, Loi S, Salgado R, Sanders M, Gonzalez-Ericsson PI, Stovgaard ES, Sua LF, Reisenbichler E, Kos Z, Carter JM, Michiels S, Le Quesne J, Nielsen TO, Laenkholm AV, Fox SB, Adam J, Bartlett JM, Rimm DL, Quinn C, Peeters D, Dieci MV, Vincent-Salomon A, Cree I, Hida AI, Balko JM, Haynes HR, Frahm I, Acosta-Haab G, Balancin M, Bellolio E, Yang W, Kirtani P, Sugie T, Ehinger A, Castaneda CA, Kok M, McArthur H, Siziopikou K, Badve S, Fineberg S, Gown A, Viale G, Schnitt SJ, Pruneri G, Penault-Llorca F, Hewitt S, Thompson EA, Allison KH,
Symmans WF
, Bellizzi AM, Brogi E, Moore DA, Larsimont D, Dillon DA,
Lazar A
, Lien H, Goetz MP, Broeckx G, El Bairi K, Harbeck N, Cimino-Mathews A, Sotiriou C, Adams S, Liu SW, Loibl S, Chen IC, Lakhani SR, Juco JW, Denkert C, Blackley EF, Demaria S, Leon-Ferre R, Gluz O, Zardavas D, Emancipator K, Ely S, Loi S, Salgado R, Sanders M, International Immuno-Oncology Biomarker Working Group, Sua LF, Michiels S, Acosta-Haab G, Balancin M, Castaneda CA, Larsimont D, Sotiriou C, Denkert C, Gluz O. The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice. J Pathol. 2020 04; 250(5):667-684.
PMID:
32129476
.
Citations:
52
Fields:
Pat
Pathology
Translation:
Humans
Cells
Ali AMR, Tsai JW, Leung CH, Lin H, Ravi V,
Conley AP
, Lazar AJ, Wang WL, Nathenson MJ, Ali AMR, Tsai JW, Leung CH, Lin H,
Ravi V
, Conley AP,
Lazar AJ
, Wang WL, Nathenson MJ. The immune microenvironment of uterine adenosarcomas. Clin Sarcoma Res. 2020; 10:5.
PMID:
32231779
; PMCID:
PMC7103067
.
Citations:
2
Groisberg R, Roszik J,
Conley AP
,
Lazar AJ
, Portal DE,
Hong DS
, Naing A, Herzog CE,
Somaiah N
, Zarzour MA, Patel S, Brown RE, Subbiah V, Groisberg R, Roszik J, Conley AP, Lazar AJ, Portal DE, Hong DS,
Naing A
,
Herzog CE
, Somaiah N,
Zarzour MA
,
Patel S
, Brown RE,
Subbiah V
. Genomics, Morphoproteomics, and Treatment Patterns of Patients with Alveolar Soft Part Sarcoma and Response to Multiple Experimental Therapies. Mol Cancer Ther. 2020 05; 19(5):1165-1172.
PMID:
32127467
; PMCID:
PMC8386165
.
Citations:
4
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Ballester LY, Meis JM, Lazar AJ,
Prabhu SS
, Hoang KB, Leeds NE,
Fuller GN
, Ballester LY,
Meis JM
,
Lazar AJ
, Prabhu SS, Hoang KB, Leeds NE, Fuller GN. Intracranial Myxoid Mesenchymal Tumor With EWSR1-ATF1 Fusion. J Neuropathol Exp Neurol. 2020 03 01; 79(3):347-351.
PMID:
32016322
.
Citations:
11
Fields:
Neu
Neurology
Pat
Pathology
Translation:
Humans
Cells
Wu CC, Beird HC, Andrew Livingston J, Advani S, Mitra A, Cao S, Reuben A, Ingram D, Wang WL, Ju Z, Hong Leung C, Lin H, Zheng Y, Roszik J, Wang W, Patel S, Benjamin RS, Somaiah N,
Conley AP
,
Mills GB
, Hwu P, Gorlick R,
Lazar A
, Daw NC, Lewis V, Futreal PA, Wu CC, Beird HC, Andrew Livingston J, Advani S, Mitra A, Cao S, Reuben A, Ingram D, Wang WL, Ju Z, Hong Leung C, Lin H, Zheng Y, Roszik J, Wang W,
Patel S
, Benjamin RS,
Somaiah N
, Conley AP, Mills GB,
Hwu P
, Gorlick R, Lazar A, Daw NC,
Lewis V
, Futreal PA. Immuno-genomic landscape of osteosarcoma. Nat Commun. 2020 02 21; 11(1):1008.
PMID:
32081846
; PMCID:
PMC7035358
.
Citations:
59
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
El Beaino M, Jupiter DC, Assi T, Rassy E,
Lazar AJ
,
Araujo DM
, Lin PP, El Beaino M, Jupiter DC, Assi T, Rassy E, Lazar AJ, Araujo DM,
Lin PP
. Diagnostic Value of TLE1 in Synovial Sarcoma: A Systematic Review and Meta-Analysis. Sarcoma. 2020; 2020:7192347.
PMID:
32322158
; PMCID:
PMC7166261
.
Citations:
5
Haydu LE, Lo SN,
McQuade JL
,
Amaria RN
, Wargo J,
Ross MI
, Cormier JN, Lucci A, Lee JE,
Ferguson SD
, Saw RPM, Spillane AJ, Shannon KF, Stretch JR,
Hwu P
, Patel SP,
Diab A
, Wong MKK, Glitza Oliva IC,
Tawbi H
, Carlino MS, Menzies AM, Long GV,
Lazar AJ
,
Tetzlaff MT
, Scolyer RA,
Gershenwald JE
, Thompson JF,
Davies MA
, Haydu LE, Lo SN, McQuade JL, Amaria RN,
Wargo J
, Ross MI,
Cormier JN
,
Lucci A
, Lee JE, Ferguson SD, Saw RPM, Spillane AJ, Shannon KF, Stretch JR, Hwu P,
Patel SP
, Diab A, Wong MKK, Glitza Oliva IC, Tawbi H, Carlino MS, Menzies AM, Long GV, Lazar AJ, Tetzlaff MT, Scolyer RA, Gershenwald JE, Thompson JF, Davies MA. Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma. J Clin Oncol. 2020 05 01; 38(13):1429-1441.
PMID:
31990608
; PMCID:
PMC7193747
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Chopra S,
Lazar AJ
, Wang WL, Chopra S, Lazar AJ, Wang WL. Are ALK rearrangements found in smooth muscle tumours of the gastrointestinal tract? Histopathology. 2020 03; 76(4):627-628.
PMID:
31596959
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H,
Amaria RN
,
Tawbi HA
, Cogdill AP, Liu W,
LeBleu VS
, Kugeratski FG, Patel S,
Davies MA
,
Hwu P
, Lee JE,
Gershenwald JE
, Lucci A, Arora R, Woodman S, Keung EZ, Gaudreau PO, Reuben A, Spencer CN, Burton EM, Haydu LE,
Lazar AJ
, Zapassodi R, Hudgens CW, Ledesma DA, Ong S, Bailey M, Warren S, Rao D, Krijgsman O, Rozeman EA, Peeper D, Blank CU, Schumacher TN, Butterfield LH, Zelazowska MA,
McBride KM
,
Kalluri R
, Allison J, Petitprez F, Fridman WH, Sautès-Fridman C, Hacohen N, Rezvani K,
Sharma P
,
Tetzlaff MT
, Wang L, Wargo JA, Helmink BA, Reddy SM,
Gao J
, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, Cogdill AP, Liu W, LeBleu VS, Kugeratski FG, Patel S, Davies MA, Hwu P, Lee JE, Gershenwald JE,
Lucci A
, Arora R,
Woodman S
, Keung EZ, Gaudreau PO, Reuben A, Spencer CN, Burton EM, Haydu LE, Lazar AJ, Zapassodi R, Hudgens CW, Ledesma DA, Ong S, Bailey M, Warren S, Rao D, Krijgsman O, Rozeman EA, Peeper D, Blank CU, Schumacher TN, Butterfield LH, Zelazowska MA, McBride KM, Kalluri R,
Allison J
, Petitprez F, Fridman WH, Sautès-Fridman C, Hacohen N, Rezvani K, Sharma P, Tetzlaff MT, Wang L,
Wargo JA
, Saut?s-Fridman C. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020 01; 577(7791):549-555.
PMID:
31942075
; PMCID:
PMC8762581
.
Citations:
512
Fields:
Sci
Science
Translation:
Humans
Cells
Petitprez F, de Reyniès A, Keung EZ, Chen TW, Sun CM, Calderaro J, Jeng YM, Hsiao LP, Lacroix L, Bougoüin A, Moreira M, Lacroix G, Natario I, Adam J, Lucchesi C, Laizet YH, Toulmonde M, Burgess MA, Bolejack V, Reinke D, Wani KM, Wang WL,
Lazar AJ
, Roland CL, Wargo JA, Italiano A, Sautès-Fridman C,
Tawbi HA
, Fridman WH, Petitprez F, de Reyniès A, Keung EZ, Chen TW, Sun CM, Calderaro J, Jeng YM, Hsiao LP, Lacroix L, Bougoüin A, Moreira M, Lacroix G, Natario I, Adam J, Lucchesi C, Laizet YH, Toulmonde M, Burgess MA, Bolejack V, Reinke D, Wani KM, Wang WL, Lazar AJ,
Roland CL
,
Wargo JA
, Italiano A, Sautès-Fridman C, Tawbi HA, Fridman WH, de Reyni?s A, Bougo?in A, Lucchesi C, Laizet YH, Toulmonde M, Italiano A, Saut?s-Fridman C. B cells are associated with survival and immunotherapy response in sarcoma. Nature. 2020 01; 577(7791):556-560.
PMID:
31942077
.
Citations:
441
Fields:
Sci
Science
Translation:
Humans
Cells
Keung EZ, Burgess M, Salazar R, Parra ER, Rodrigues-Canales J, Bolejack V, Van Tine BA, Schuetze SM, Attia S, Riedel RF, Hu J, Okuno SH, Priebat DA, Movva S, Davis LE, Reed DR, Reuben A, Roland CL, Reinke D, Lazar AJ, Wang WL, Wargo JA,
Tawbi HA
, Keung EZ, Burgess M, Salazar R, Parra ER, Rodrigues-Canales J, Bolejack V, Van Tine BA, Schuetze SM, Attia S, Riedel RF, Hu J, Okuno SH, Priebat DA, Movva S, Davis LE, Reed DR, Reuben A,
Roland CL
, Reinke D,
Lazar AJ
, Wang WL,
Wargo JA
, Tawbi HA. Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab. Clin Cancer Res. 2020 03 15; 26(6):1258-1266.
PMID:
31900276
; PMCID:
PMC7731262
.
Citations:
49
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S,
Lazar AJ
, Pant S, Meric-Bernstam F, Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S, Lazar AJ,
Pant S
,
Meric-Bernstam F
. Overview of the TREC 2019 Precision Medicine Track. Text Retr Conf. 2019 Nov; 1250.
PMID:
34849512
; PMCID:
PMC8629155
.
Citations:
1
Bishop AJ
, Bird JE,
Conley AP
, Roland CL, Moon BS, Satcher RL, Livingston JA,
Patel S
, Wang WL, Lazar AJ,
Lewis VO
,
Lin PP
,
Guadagnolo BA
, Bishop AJ,
Bird JE
, Conley AP,
Roland CL
,
Moon BS
,
Satcher RL
,
Livingston JA
, Patel S, Wang WL,
Lazar AJ
, Lewis VO, Lin PP, Guadagnolo BA. Extraskeletal Myxoid Chondrosarcomas: Combined Modality Therapy With Both Radiation and Surgery Improves Local Control. Am J Clin Oncol. 2019 10; 42(10):744-748.
PMID:
31436747
; PMCID:
PMC7771031
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Molina ER, Chim LK, Salazar MC, Mehta SM, Menegaz BA, Lamhamedi-Cherradi SE, Satish T, Mohiuddin S, McCall D, Zaske AM, Cuglievan B,
Lazar AJ
, Scott DW, Grande-Allen JK,
Ludwig JA
, Mikos AG, Molina ER, Chim LK, Salazar MC, Mehta SM, Menegaz BA, Lamhamedi-Cherradi SE, Satish T, Mohiuddin S, McCall D, Zaske AM, Cuglievan B, Lazar AJ, Scott DW, Grande-Allen JK, Ludwig JA, Mikos AG. Mechanically tunable coaxial electrospun models of YAP/TAZ mechanoresponse and IGF-1R activation in osteosarcoma. Acta Biomater. 2019 12; 100:38-51.
PMID:
31542501
; PMCID:
PMC7027943
.
Citations:
14
Fields:
Bio
Biomedical Engineering
Translation:
Humans
Cells
Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I, Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Cancer Genome Atlas Research Network,
Lazar AJ
, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I, Thorsson V, Malta TM, Noushmehr H, Demicco EG. The Immune Landscape of Cancer. Immunity. 2019 Aug 20; 51(2):411-412.
PMID:
31433971
.
Citations:
119
Fields:
All
Allergy and Immunology
Nagarajan P
, Piao J,
Ning J
, Noordenbos LE,
Curry JL
, Torres-Cabala CA, Diwan AH,
Ivan D
, Aung PP,
Ross MI
, Royal RE, Wargo JA, Wang WL, Samdani R,
Lazar AJ
,
Rashid A
,
Davies MA
,
Prieto VG
,
Gershenwald JE
,
Tetzlaff MT
, Nagarajan P, Piao J, Ning J, Noordenbos LE, Curry JL, Torres-Cabala CA,
Diwan AH
, Ivan D,
Aung PP
, Ross MI,
Royal RE
,
Wargo JA
, Wang WL, Samdani R, Lazar AJ, Rashid A, Davies MA, Prieto VG, Gershenwald JE, Tetzlaff MT. Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features. Mod Pathol. 2020 03; 33(3):496-513.
PMID:
31383963
.
Citations:
4
Fields:
Pat
Pathology
Translation:
Humans
Bonvalot S, Rutkowski PL, Thariat J, Carrère S, Ducassou A, Sunyach MP, Agoston P, Hong A, Mervoyer A, Rastrelli M, Moreno V, Li RK, Tiangco B, Herraez AC, Gronchi A, Mangel L, Sy-Ortin T, Hohenberger P, de Baère T, Le Cesne A, Helfre S, Saada-Bouzid E, Borkowska A, Anghel R, Co A, Gebhart M, Kantor G, Montero A, Loong HH, Vergés R, Lapeire L, Dema S, Kacso G, Austen L, Moureau-Zabotto L, Servois V, Wardelmann E, Terrier P,
Lazar AJ
, Bovée JVMG, Le Péchoux C, Papai Z, Bonvalot S, Rutkowski PL, Thariat J, Carrère S, Ducassou A, Sunyach MP, Agoston P, Hong A, Mervoyer A, Rastrelli M, Moreno V, Li RK, Tiangco B, Herraez AC, Gronchi A, Mangel L, Sy-Ortin T, Hohenberger P, de Baère T, Le Cesne A, Helfre S, Saada-Bouzid E, Borkowska A, Anghel R, Co A, Gebhart M, Kantor G, Montero A, Loong HH, Vergés R, Lapeire L, Dema S, Kacso G, Austen L, Moureau-Zabotto L, Servois V, Wardelmann E, Terrier P, Lazar AJ, Bovée JVMG, Le Péchoux C, Papai Z, Thariat J, Carr?re S, Sunyach MP, Agoston P, Moreno V, Tiangco B, Mangel L, de Ba?re T, Kantor G, Verg?s R, Wardelmann E, Bov?e JVMG, Le P?choux C. NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2-3, randomised, controlled trial. Lancet Oncol. 2019 08; 20(8):1148-1159.
PMID:
31296491
.
Citations:
71
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Chrisinger JSA, Al-Zaid T, Keung EZ, Leung C, Lin HY, Roland CL, Torres KE, Benjamin RS, Ingram DR, Khan S, Somaiah N,
Amini B
,
Feig BW
, Lazar AJ, Wang WL, Chrisinger JSA, Al-Zaid T, Keung EZ, Leung C, Lin HY,
Roland CL
,
Torres KE
, Benjamin RS, Ingram DR, Khan S,
Somaiah N
, Amini B, Feig BW,
Lazar AJ
, Wang WL. The degree of sclerosis is associated with prognosis in well-differentiated liposarcoma of the retroperitoneum. J Surg Oncol. 2019 Sep; 120(3):382-388.
PMID:
31206726
; PMCID:
PMC7652035
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Conley AP
, Wang WL,
Livingston JA
,
Ravi V
, Tsai JW, Ali A, Ingram DR, Lowery CD,
Roland CL
,
Somaiah N
, Hwu P,
Yee C
, Subbiah V,
Futreal A
,
Lazar AJ
,
Patel S
, Roszik J, Conley AP, Wang WL, Livingston JA, Ravi V, Tsai JW, Ali A, Ingram DR, Lowery CD, Roland CL, Somaiah N,
Hwu P
, Yee C,
Subbiah V
, Futreal A, Lazar AJ, Patel S, Roszik J. MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma. Cancers (Basel). 2019 May 15; 11(5).
PMID:
31096717
; PMCID:
PMC6562561
.
Citations:
10
Vidal CI, Sutton A, Armbrect EA, Lee JB, Litzner BR, Hurley MY, Alam M, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA, Lazar AJ, Lowe L, Plaza JA, Robinson JK, Schaffer A, Task Force/Committee Members, Vidal CI, Sutton A, Armbrect EA, Lee JB, Litzner BR, Hurley MY, Rating Panel, Alam M, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA,
Lazar AJ
, Lowe L, Plaza JA, Robinson JK, Schaffer A, Emanuel PO. Muir-Torre syndrome appropriate use criteria: Effect of patient age on appropriate use scores. J Cutan Pathol. 2019 Jul; 46(7):484-489.
PMID:
30895633
.
Citations:
1
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Moncur JT, Bartley AN, Bridge JA, Kamel-Reid S, Lazar AJ, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Kim AS, Moncur JT, Bartley AN, Bridge JA, Kamel-Reid S,
Lazar AJ
, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Kim AS. Performance Comparison of Different Analytic Methods in Proficiency Testing for Mutations in the BRAF, EGFR, and KRAS Genes: A Study of the College of American Pathologists Molecular Oncology Committee. Arch Pathol Lab Med. 2019 10; 143(10):1203-1211.
PMID:
30969158
.
Citations:
1
Fields:
Pat
Pathology
Translation:
Humans
Erstine EM,
Lazar AJ
, Erstine EM, Lazar AJ. Toward an effective use of ?-catenin immunohistochemistry in the evaluation of challenging melanocytic lesions. Virchows Arch. 2019 05; 474(5):535-537.
PMID:
30868296
.
Citations:
2
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Pat
Pathology
Translation:
Humans
Bishop AJ
, Livingston JA,
Araujo DM
, Moon BS,
Patel S
, Wang WL, Lazar AJ,
Roland CL
, Guadagnolo BA, Bishop AJ, Livingston JA, Araujo DM,
Moon BS
, Patel S, Wang WL,
Lazar AJ
, Roland CL,
Guadagnolo BA
. Extraskeletal Osteosarcomas: A Case Made for Combined Modality Local Therapy With Radiation and Surgery. Am J Clin Oncol. 2019 03; 42(3):238-242.
PMID:
30614820
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Aung PP
, Parra ER, Barua S, Sui D,
Ning J
, Mino B, Ledesma DA, Curry JL,
Nagarajan P
, Torres-Cabala CA, Efstathiou E, Hoang AG, Wong MK, Wargo JA, Lazar AJ, Rao A, Prieto VG,
Wistuba I
,
Tetzlaff MT
, Aung PP, Parra ER, Barua S, Sui D, Ning J, Mino B, Ledesma DA,
Curry JL
, Nagarajan P, Torres-Cabala CA,
Efstathiou E
, Hoang AG, Wong MK,
Wargo JA
,
Lazar AJ
, Rao A,
Prieto VG
, Wistuba I, Tetzlaff MT. B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density. Clin Cancer Res. 2019 06 01; 25(11):3455-3467.
PMID:
30808776
; PMCID:
PMC8211110
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC,
Gershenwald JE
, Vashisht Gopal YN, Hwu P, Huse JT,
Wargo JA
, Futreal PA, Putluri N,
Lazar AJ
, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL,
Tetzlaff MT
,
Davies MA
, Fischer GM,
Jalali A
, Kircher DA, Lee WC,
McQuade JL
, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR,
Sreekumar A
, Hudgens CW, Knighton B, Deng W,
Ferguson SD
,
Tawbi HA
,
Glitza IC
, Gershenwald JE, Vashisht Gopal YN,
Hwu P
,
Huse JT
, Wargo JA, Futreal PA,
Putluri N
, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA, de Macedo MP. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov. 2019 05; 9(5):628-645.
PMID:
30787016
; PMCID:
PMC6497554
.
Citations:
87
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG,
Su X
, Li L,
Lopez-Terrada D
, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A,
Maitra A
, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P,
Tannir NM
,
Draetta GF
, Genovese G, Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D,
Lazar AJ
, Netto GJ, Rao P, Sgambato A, Maitra A,
Tripathi DN
,
Walker CL
,
Karam JA
, Heffernan TP,
Viale A
, Roberts CWM, Msaouel P, Tannir NM, Draetta GF,
Genovese G
, Malouf GG, Sgambato A. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019 02 11; 35(2):204-220.e9.
PMID:
30753823
; PMCID:
PMC7876656
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A,
Raju GS
,
Stroehlein JR
, Campbell MT,
Gao J
, Subudhi SK, Maru DM, Blando JM,
Lazar AJ
,
Allison JP
,
Sharma P
,
Tetzlaff MT
, Wargo JA, Jenq RR, Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A, Raju GS, Stroehlein JR, Campbell MT, Gao J,
Subudhi SK
,
Maru DM
, Blando JM, Lazar AJ, Allison JP, Sharma P, Tetzlaff MT,
Wargo JA
, Jenq RR. Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis. Nat Med. 2019 Jan; 25(1):188.
PMID:
30479380
.
Citations:
2
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Bishop AJ, Zarzour MA,
Ratan R
, Torres KE, Feig BW, Wang WL, Lazar AJ, Moon BS,
Roland CL
,
Guadagnolo BA
,
Bishop AJ
,
Zarzour MA
, Ratan R,
Torres KE
,
Feig BW
, Wang WL,
Lazar AJ
,
Moon BS
, Roland CL, Guadagnolo BA. Long-Term Outcomes for Patients With Desmoid Fibromatosis Treated With Radiation Therapy: A 10-Year Update and Re-evaluation of the Role of Radiation Therapy for Younger Patients. Int J Radiat Oncol Biol Phys. 2019 04 01; 103(5):1167-1174.
PMID:
30552963
.
Citations:
4
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Amaria RN, Reddy SM, Tawbi HA, Davies MA,
Ross MI
, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK,
Royal R
, Gross N,
Weber R
, Lai SY, Ehlers R, Blando J, Milton DR,
Woodman S
, Kageyama R, Wells DK, Hwu P, Patel SP,
Lucci A
,
Hessel A
, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S,
Lazar AJ
, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN,
Prieto V
, Sharma P, Allison J, Tetzlaff MT,
Wargo JA
,
Amaria RN
, Reddy SM,
Tawbi HA
,
Davies MA
, Ross MI,
Glitza IC
,
Cormier JN
, Lewis C,
Hwu WJ
,
Hanna E
,
Diab A
, Wong MK, Royal R,
Gross N
, Weber R,
Lai SY
, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK,
Hwu P
,
Patel SP
, Lucci A, Hessel A, Lee JE,
Gershenwald J
, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V,
Sharma P
,
Allison J
,
Tetzlaff MT
, Wargo JA, Milton DR. Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 Dec; 24(12):1941.
PMID:
30361510
.
Citations:
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Amaria RN, Reddy SM,
Tawbi HA
, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ,
Hanna E
, Diab A, Wong MK,
Royal R
, Gross N,
Weber R
, Lai SY, Ehlers R, Blando J, Milton DR,
Woodman S
, Kageyama R, Wells DK, Hwu P, Patel SP,
Lucci A
,
Hessel A
, Lee JE,
Gershenwald J
, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S,
Lazar AJ
, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J,
Tetzlaff MT
, Wargo JA,
Amaria RN
, Reddy SM, Tawbi HA,
Davies MA
,
Ross MI
,
Glitza IC
,
Cormier JN
, Lewis C,
Hwu WJ
, Hanna E,
Diab A
, Wong MK, Royal R,
Gross N
, Weber R,
Lai SY
, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK,
Hwu P
,
Patel SP
, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN,
Prieto V
,
Sharma P
,
Allison J
, Tetzlaff MT,
Wargo JA
, Milton DR. Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 Dec; 24(12):1942.
PMID:
30361511
.
Citations:
5
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A,
Raju GS
, Stroehlein JR, Campbell MT,
Gao J
, Subudhi SK,
Maru DM
, Blando JM,
Lazar AJ
, Allison JP,
Sharma P
,
Tetzlaff MT
,
Wargo JA
, Jenq RR, Wang Y, Wiesnoski DH, Helmink BA, Gopalakrishnan V, Choi K, DuPont HL, Jiang ZD, Abu-Sbeih H, Sanchez CA, Chang CC, Parra ER, Francisco-Cruz A, Raju GS,
Stroehlein JR
, Campbell MT, Gao J,
Subudhi SK
, Maru DM, Blando JM, Lazar AJ,
Allison JP
, Sharma P, Tetzlaff MT, Wargo JA, Jenq RR. Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis. Nat Med. 2018 12; 24(12):1804-1808.
PMID:
30420754
; PMCID:
PMC6322556
.
Citations:
183
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Merker JD, Devereaux K, Iafrate AJ, Kamel-Reid S, Kim AS, Moncur JT, Montgomery SB, Nagarajan R, Portier BP, Routbort MJ, Smail C, Surrey LF, Vasalos P,
Lazar AJ
, Lindeman NI, Merker JD, Devereaux K, Iafrate AJ, Kamel-Reid S, Kim AS, Moncur JT, Montgomery SB, Nagarajan R, Portier BP,
Routbort MJ
, Smail C, Surrey LF, Vasalos P, Lazar AJ, Lindeman NI. Proficiency Testing of Standardized Samples Shows Very High Interlaboratory Agreement for Clinical Next-Generation Sequencing-Based Oncology Assays. Arch Pathol Lab Med. 2019 04; 143(4):463-471.
PMID:
30376374
; PMCID:
PMC6910717
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
McKean M, Oba J, Ma J, Roth KG, Wang WL, Macedo MP, Carapeto FCL, Haydu LE, Siroy AE, Vo P,
Hong DS
,
Eterovic AK
, Patel KP, Bassett RL, Grimm EA,
Lazar AJ
, Woodman SE, McKean M, Oba J, Ma J, Roth KG, Wang WL, Macedo MP, Carapeto FCL, Haydu LE, Siroy AE, Vo P, Hong DS, Eterovic AK, Patel KP, Bassett RL,
Grimm EA
, Lazar AJ,
Woodman SE
, Macedo MP. Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma. J Invest Dermatol. 2019 03; 139(3):728-731.
PMID:
30798855
.
Citations:
4
Fields:
Der
Dermatology
Translation:
Humans
Aires DJ, Yoshida M, Richardson SK, Bai M, Liu L, Moreno R,
Lazar AJF
, Wick JA, Rich BE, Murphy G, Blumberg RS, Fuhlbrigge RC, Kupper TS, Aires DJ, Yoshida M, Richardson SK, Bai M, Liu L, Moreno R, Lazar AJF, Wick JA, Rich BE, Murphy G, Blumberg RS, Fuhlbrigge RC, Kupper TS. T-cell trafficking plays an essential role in tumor immunity. Lab Invest. 2019 01; 99(1):85-92.
PMID:
30353131
; PMCID:
PMC6309214
.
Citations:
1
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Animals
Cells
Amaria RN
, Reddy SM, Tawbi HA,
Davies MA
,
Ross MI
,
Glitza IC
,
Cormier JN
, Lewis C,
Hwu WJ
,
Hanna E
,
Diab A
, Wong MK,
Royal R
,
Gross N
,
Weber R
, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK,
Hwu P
, Patel SP, Lucci A,
Hessel A
, Lee JE,
Gershenwald J
, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S,
Lazar AJ
, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN,
Prieto V
,
Sharma P
,
Allison J
, Tetzlaff MT, Wargo JA, Amaria RN, Reddy SM,
Tawbi HA
, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R,
Lai SY
, Ehlers R, Blando J, Milton DR,
Woodman S
, Kageyama R, Wells DK, Hwu P,
Patel SP
,
Lucci A
, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J,
Tetzlaff MT
,
Wargo JA
, Milton DR. Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 11; 24(11):1649-1654.
PMID:
30297909
; PMCID:
PMC6481682
.
Citations:
220
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
CT
Clinical Trials
Keung EZ, Lazar AJ, Torres KE, Wang WL,
Cormier JN
, Ashleigh Guadagnolo B,
Bishop AJ
, Lin H, Hunt KK,
Bird J
, Lewis VO, Patel SR,
Wargo JA
,
Somaiah N
,
Roland CL
, Keung EZ,
Lazar AJ
,
Torres KE
, Wang WL, Cormier JN, Ashleigh Guadagnolo B, Bishop AJ, Lin H,
Hunt KK
, Bird J,
Lewis VO
,
Patel SR
, Wargo JA, Somaiah N, Roland CL. Phase II study of neoadjuvant checkpoint blockade in patients with surgically resectable undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma. BMC Cancer. 2018 Sep 24; 18(1):913.
PMID:
30249211
; PMCID:
PMC6154892
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Demicco EG, Wani K, Ingram D, Wagner M, Maki RG, Rizzo A, Meeker A, Lazar AJ, Wang WL, Demicco EG, Wani K, Ingram D, Wagner M, Maki RG, Rizzo A, Meeker A,
Lazar AJ
, Wang WL. TERT promoter mutations in solitary fibrous tumour. Histopathology. 2018 Nov; 73(5):843-851.
PMID:
29985536
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
Cells
Roszik J, Ring KL, Wani KM,
Lazar AJ
, Yemelyanova AV, Soliman PT,
Frumovitz M
, Jazaeri AA, Roszik J, Ring KL, Wani KM, Lazar AJ,
Yemelyanova AV
,
Soliman PT
, Frumovitz M,
Jazaeri AA
. Gene Expression Analysis Identifies Novel Targets for Cervical Cancer Therapy. Front Immunol. 2018; 9:2102.
PMID:
30283446
; PMCID:
PMC6156434
.
Citations:
13
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Liu Y, Weber Z, San Lucas FA, Deshpande A, Jakubek YA, Sulaiman R, Fagerness M, Flier N, Sulaiman J, Davis CM, Fowler J, Starks D, Rojas-Espaillat L, Lazar AJ, Davies GE, Ehli EA,
Scheet P
, Liu Y, Weber Z, San Lucas FA, Deshpande A, Jakubek YA, Sulaiman R, Fagerness M, Flier N, Sulaiman J, Davis CM, Fowler J, Starks D, Rojas-Espaillat L,
Lazar AJ
, Davies GE, Ehli EA, Scheet P. Assessing inter-component heterogeneity of biphasic uterine carcinosarcomas. Gynecol Oncol. 2018 11; 151(2):243-249.
PMID:
30194005
; PMCID:
PMC6214727
.
Citations:
6
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Nathenson MJ,
Conley AP
, Lin H,
Fleming N
, Lazar A, Wang WL, Ravi V, Nathenson MJ, Conley AP, Lin H, Fleming N,
Lazar A
, Wang WL,
Ravi V
. The Importance of Lymphovascular Invasion in Uterine Adenosarcomas: Analysis of Clinical, Prognostic, and Treatment Outcomes. Int J Gynecol Cancer. 2018 09; 28(7):1297-1310.
PMID:
30044322
.
Citations:
3
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Kwok-Shing Ng P, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J,
Wheeler D
, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L, Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Kwok-Shing Ng P, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, MC3 Working Group, Cancer Genome Atlas Research Network, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K,
Lazar AJ
,
Mills GB
, Karchin R, Ding L, Cort?s-Ciriano I. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018 08 09; 174(4):1034-1035.
PMID:
30096302
; PMCID:
PMC8045146
.
Citations:
173
Fields:
Cel
Cell Biology
Charville GW, Lazar AJ, Charville GW,
Lazar AJ
. Prognostic gene expression signatures in sarcoma: finding clarity in complexity. Ann Oncol. 2018 08 01; 29(8):1632-1633.
PMID:
29982358
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Charville GW, Wang WL, Ingram DR,
Roy A
, Thomas D, Patel RM, Hornick JL, van de Rijn M, Lazar AJ, Charville GW, Wang WL, Ingram DR, Roy A, Thomas D, Patel RM, Hornick JL, van de Rijn M,
Lazar AJ
. PAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation. Mod Pathol. 2019 01; 32(1):154-156.
PMID:
29985454
.
Citations:
5
Fields:
Pat
Pathology
Translation:
Humans
Kwong LN, De Macedo MP, Haydu L, Joon AY,
Tetzlaff MT
, Calderone TL, Wu CJ, Kwong MK, Roszik J,
Hess KR
,
Davies MA
, Lazar AJ, Gershenwald JE,
Kwong LN
, De Macedo MP, Haydu L, Joon AY, Tetzlaff MT, Calderone TL, Wu CJ, Kwong MK, Roszik J, Hess KR, Davies MA,
Lazar AJ
,
Gershenwald JE
. Biological Validation of RNA Sequencing Data from Formalin-Fixed Paraffin-Embedded Primary Melanomas. JCO Precis Oncol. 2018; 2018.
PMID:
31058252
; PMCID:
PMC6498859
.
Citations:
10
Fields:
Neo
Neoplasms
Vidal CI, Armbrect EA, Andea AA, Bohlke AK, Comfere NI, Hughes SR, Kim J, Kozel JA, Lee JB, Linos K, Litzner BR, Missall TA, Novoa RA, Sundram U, Swick BL, Hurley MY, Alam M, Argenyi Z, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA,
Lazar AJ
, Lowe L, Plaza JA,
Prieto VG
, Robinson JK, Schaffer A, Subtil A, Wang WL, Vidal CI, Armbrect EA, Andea AA, Bohlke AK, Comfere NI, Hughes SR, Kim J, Kozel JA, Lee JB, Linos K, Litzner BR, Missall TA, Novoa RA, Sundram U, Swick BL, Hurley MY, Alam M, Argenyi Z, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA, Lazar AJ, Lowe L, Plaza JA, Prieto VG, Robinson JK, Schaffer A, Subtil A, Wang WL. Appropriate use criteria in dermatopathology: Initial recommendations from the American Society of Dermatopathology. J Cutan Pathol. 2018 Aug; 45(8):563-580.
PMID:
29566273
.
Citations:
3
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Subbiah V
, Lamhamedi-Cherradi SE, Cuglievan B, Menegaz BA,
Camacho P
,
Huh W
, Ramamoorthy V, Anderson PM, Pollock RE, Lev DC, Qiao W,
McAleer MF
, Benjamin RS,
Patel S
, Herzog CE, Daw NC,
Feig BW
,
Lazar AJ
,
Hayes-Jordan A
, Ludwig JA, Subbiah V, Lamhamedi-Cherradi SE, Cuglievan B, Menegaz BA, Camacho P, Huh W, Ramamoorthy V, Anderson PM, Pollock RE, Lev DC, Qiao W, McAleer MF, Benjamin RS, Patel S,
Herzog CE
, Daw NC, Feig BW, Lazar AJ, Hayes-Jordan A,
Ludwig JA
. Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival. Clin Cancer Res. 2018 10 01; 24(19):4865-4873.
PMID:
29871905
; PMCID:
PMC6168359
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Oba J, Kim SH, Wang WL, Macedo MP, Carapeto F, McKean MA, Van Arnam J,
Eterovic AK
, Sen S, Kale CR, Yu X, Haymaker CL, Routbort M, Haydu LE,
Bernatchez C
, Lazar AJ, Grimm EA, Hong DS,
Woodman SE
, Oba J, Kim SH, Wang WL, Macedo MP, Carapeto F, McKean MA, Van Arnam J, Eterovic AK, Sen S, Kale CR, Yu X, Haymaker CL, Routbort M, Haydu LE, Bernatchez C, Lazar AJ,
Grimm EA
, Hong DS, Woodman SE, Oba J, Kim SH, Wang WL, Macedo MP, Carapeto F, McKean MA, Van Arnam J, Eterovic AK, Sen S, Kale CR, Yu X,
Haymaker CL
,
Routbort M
, Haydu LE, Bernatchez C,
Lazar AJ
, Grimm EA,
Hong DS
, Woodman SE. Targeting the HGF/MET Axis Counters Primary Resistance to KIT Inhibition in KIT-Mutant Melanoma. JCO Precis Oncol. 2018; 2018.
PMID:
30094412
; PMCID:
PMC6080631
.
Citations:
9
Fields:
Neo
Neoplasms
Kim AS, Bartley AN, Bridge JA, Kamel-Reid S,
Lazar AJ
, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Moncur JT, Kim AS, Bartley AN, Bridge JA, Kamel-Reid S, Lazar AJ, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Moncur JT. Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing. JAMA Oncol. 2018 06 01; 4(6):838-841.
PMID:
29242895
; PMCID:
PMC6145687
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM, Araujo DM, Wang WL, Tsai JW, Yeagley M, Wagner AJ, Futreal PA, Khan J, Lazar AJ, Kadoch C, McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM,
Araujo DM
, Wang WL, Tsai JW, Yeagley M, Wagner AJ, Futreal PA, Khan J,
Lazar AJ
, Kadoch C. The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma. Cancer Cell. 2018 06 11; 33(6):1128-1141.e7.
PMID:
29861296
; PMCID:
PMC6791822
.
Citations:
65
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kim G, Kurnit KC, Djordjevic B, Singh C, Munsell MF, Wang WL,
Lazar AJ
, Zhang W, Broaddus R, Kim G, Kurnit KC, Djordjevic B, Singh C, Munsell MF, Wang WL, Lazar AJ, Zhang W,
Broaddus R
. Nuclear ?-catenin localization and mutation of the CTNNB1 gene: a context-dependent association. Mod Pathol. 2018 10; 31(10):1553-1559.
PMID:
29795437
; PMCID:
PMC6168348
.
Citations:
29
Fields:
Pat
Pathology
Translation:
Humans
Cells
Bezrookove V, Nosrati M, Miller JR, De Semir D, Dar AA, Vosoughi E, Vaquero E, Sucker A,
Lazar AJ
,
Gershenwald JE
, Davies MA, Schadendorf D, Kashani-Sabet M, Bezrookove V, Nosrati M, Miller JR, De Semir D, Dar AA, Vosoughi E, Vaquero E, Sucker A, Lazar AJ, Gershenwald JE, Davies MA, Schadendorf D, Kashani-Sabet M. Role of Elevated PHIP Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma. Clin Cancer Res. 2018 09 01; 24(17):4119-4125.
PMID:
29776954
; PMCID:
PMC6125189
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Chen H, Luthra R, Patel KP,
Routbort M
, Rashid A, Roy-Chowdhuri S, Lazar A, Broaddus R, Manekia J, Singh RR, Yemelyanova A, Chen H,
Luthra R
,
Patel KP
, Routbort M,
Rashid A
, Roy-Chowdhuri S,
Lazar A
,
Broaddus R
, Manekia J, Singh RR,
Yemelyanova A
. Challenges in next generation sequencing analysis of somatic mutations in transplant patients. Cancer Genet. 2018 10; 226-227:17-22.
PMID:
30005850
.
Citations:
Fields:
Gen
Genetics
Neo
Neoplasms
Translation:
Humans
Keung EZ, Ikoma N, Benjamin R, Wang WL, Lazar AJ, Feig BW, Keung EZ, Ikoma N, Benjamin R, Wang WL,
Lazar AJ
,
Feig BW
. The clinical behavior of well differentiated liposarcoma can be extremely variable: A retrospective cohort study at a major sarcoma center. J Surg Oncol. 2018 Jun; 117(8):1799-1805.
PMID:
29723411
; PMCID:
PMC6904950
.
Citations:
3
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Vidal CI, Armbrect EA, Andea AA, Bohlke AK, Comfere NI, Hughes SR, Kim J, Kozel JA, Lee JB, Linos K, Litzner BR, Missall TA, Novoa RA, Sundram U, Swick BL, Hurley MY, Alam M, Argenyi Z, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA, Lazar AJ, Lowe L, Plaza JA, Prieto VG, Robinson JK, Schaffer A, Subtil A, Wang WL, Task Force/Committee Members, Vidal CI, Armbrect EA, Andea AA, Bohlke AK, Comfere NI, Hughes SR, Kim J, Kozel JA, Lee JB, Linos K, Litzner BR, Missall TA, Novoa RA, Sundram U, Swick BL, Hurley MY, Rating Panel, Alam M, Argenyi Z, Duncan LM, Elston DM, Emanuel PO, Ferringer T, Fung MA, Hosler GA,
Lazar AJ
, Lowe L, Plaza JA,
Prieto VG
, Robinson JK, Schaffer A, Subtil A, Wang WL. Appropriate use criteria in dermatopathology: Initial recommendations from the American Society of Dermatopathology. J Am Acad Dermatol. 2019 Jan; 80(1):189-207.e11.
PMID:
29689323
.
Citations:
2
Fields:
Der
Dermatology
Translation:
Humans
Somaiah N, Beird HC, Barbo A, Song J, Mills Shaw KR, Wang WL, Eterovic K, Chen K,
Lazar A
, Conley AP, Ravi V, Hwu P, Futreal A,
Simon G
,
Meric-Bernstam F
, Hong D,
Somaiah N
, Beird HC, Barbo A, Song J, Mills Shaw KR, Wang WL, Eterovic K, Chen K, Lazar A,
Conley AP
,
Ravi V
,
Hwu P
,
Futreal A
, Simon G, Meric-Bernstam F,
Hong D
. Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations. Oncotarget. 2018 Apr 13; 9(28):19891-19899.
PMID:
29731991
; PMCID:
PMC5929434
.
Citations:
7
Fields:
Neo
Neoplasms
Hoadley KA, Yau C, Hinoue T, Wolf DM,
Lazar AJ
, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V,
Akbani R
, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, Robertson AG, Schneider BG, Lawrence MS, Noushmehr H, Malta TM, Stuart JM, Benz CC, Laird PW, Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, Robertson AG, Schneider BG, Lawrence MS, Noushmehr H, Malta TM, Cancer Genome Atlas Network, Stuart JM, Benz CC, Laird PW, Thorsson V, Sanchez-Vega F. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell. 2018 04 05; 173(2):291-304.e6.
PMID:
29625048
; PMCID:
PMC5957518
.
Citations:
682
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG,
Lazar AJ
, Hammer GD, Giordano T, Kwong LN, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Schultz N, Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG, Lazar AJ, Hammer GD, Giordano T,
Kwong LN
, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M, Cancer Genome Atlas Research Network, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Schultz N, Sanchez-Vega F, Armenia J, Chatila WK, La KC, Chakravarty D, Daian F, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Schultz N. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 2018 04 05; 173(2):321-337.e10.
PMID:
29625050
; PMCID:
PMC6070353
.
Citations:
805
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L,
Weinstein JN
, Kaminska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwinska P, Mazurek S, Mishra L, Heyn H, Krasnitz A, Godwin AK, Lazar AJ, Stuart JM, Hoadley KA, Laird PW, Noushmehr H, Wiznerowicz M, Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kaminska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwinska P, Mazurek S, Mishra L, Heyn H, Krasnitz A, Godwin AK,
Lazar AJ
, Cancer Genome Atlas Research Network, Stuart JM, Hoadley KA, Laird PW, Noushmehr H, Wiznerowicz M, Malta TM, Colaprico A, Noushmehr H. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell. 2018 04 05; 173(2):338-354.e15.
PMID:
29625051
; PMCID:
PMC5902191
.
Citations:
467
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK,
Weinstein JN
, Guinney J, Saltz J, Holt RA, Rabkin CS, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I, Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Cancer Genome Atlas Research Network,
Lazar AJ
, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I, Thorsson V, Malta TM, Noushmehr H, Demicco EG. The Immune Landscape of Cancer. Immunity. 2018 04 17; 48(4):812-830.e14.
PMID:
29628290
; PMCID:
PMC5982584
.
Citations:
1407
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Cortés-Ciriano I, Jayasinghe R, Chen F, Yu L, Sun S, Olsen C, Kim J, Taylor AM, Cherniack AD,
Akbani R
, Suphavilai C, Nagarajan N, Stuart JM, Mills GB, Wyczalkowski MA, Vincent BG, Hutter CM, Zenklusen JC, Hoadley KA, Wendl MC, Shmulevich L, Lazar AJ,
Wheeler DA
, Getz G, Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Cortés-Ciriano I, Jayasinghe R, Chen F, Yu L, Sun S, Olsen C, Kim J, Taylor AM, Cherniack AD, Akbani R, Suphavilai C, Nagarajan N, Stuart JM,
Mills GB
, Wyczalkowski MA, Vincent BG, Hutter CM, Zenklusen JC, Hoadley KA, Wendl MC, Shmulevich L,
Lazar AJ
, Wheeler DA, Getz G, Cancer Genome Atlas Research Network, Colaprico A, Cort?s-Ciriano I, Olsen C. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell. 2018 04 05; 173(2):305-320.e10.
PMID:
29625049
; PMCID:
PMC5916814
.
Citations:
118
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ,
Lichtarge O
, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S,
Wheeler D
, Kulkarni S, Dipersio JF, Reimand J,
Meric-Bernstam F
, Chen K, Shmulevich I, Plon SE, Chen F, Ding L, Huang KL, Mashl RJ, Wu Y,
Ritter DI
, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Cancer Genome Atlas Research Network, Lichtarge O, Boutros PC, Raphael B,
Lazar AJ
, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I,
Plon SE
, Chen F, Ding L, Reimand J. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell. 2018 04 05; 173(2):355-370.e14.
PMID:
29625052
; PMCID:
PMC5949147
.
Citations:
239
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J,
Wheeler D
, Getz G, Chen K,
Lazar AJ
,
Mills GB
, Karchin R, Ding L, Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, MC3 Working Group, Cancer Genome Atlas Research Network, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L, Colaprico A, Cort?s-Ciriano I, Lopez-Bigas N. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018 04 05; 173(2):371-385.e18.
PMID:
29625053
; PMCID:
PMC6029450
.
Citations:
625
Fields:
Cel
Cell Biology
Translation:
Humans
Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V,
Akbani R
, Byers LA, Creighton CJ,
Coarfa C
, Shih J, Cherniack AD, Gevaert O, Prunello M, Shen H, Anur P, Chen J, Cheng H, Hayes DN, Bullman S, Pedamallu CS, Ojesina AI, Sadeghi S, Mungall KL, Robertson AG, Benz C, Schultz A, Kanchi RS, Gay CM, Hegde A, Diao L, Wang J, Ma W,
Sumazin P
,
Chiu HS
, Chen TW,
Gunaratne P
, Donehower L, Rader JS, Zuna R, Al-Ahmadie H, Lazar AJ, Flores ER, Tsai KY, Zhou JH, Rustgi AK, Drill E, Shen R, Wong CK, Stuart JM, Laird PW, Hoadley KA,
Weinstein JN
, Peto M,
Pickering CR
, Chen Z, Van Waes C, Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R,
Byers LA
,
Creighton CJ
, Coarfa C, Shih J, Cherniack AD, Gevaert O, Prunello M, Shen H, Anur P, Chen J, Cheng H, Hayes DN, Bullman S, Pedamallu CS, Ojesina AI, Sadeghi S, Mungall KL, Robertson AG, Benz C, Schultz A, Kanchi RS, Gay CM, Hegde A, Diao L, Wang J, Ma W, Sumazin P, Chiu HS, Chen TW, Gunaratne P, Donehower L, Rader JS, Zuna R, Al-Ahmadie H,
Lazar AJ
, Flores ER, Tsai KY, Zhou JH, Rustgi AK, Drill E, Shen R, Wong CK, Cancer Genome Atlas Research Network, Stuart JM, Laird PW, Hoadley KA, Weinstein JN, Peto M, Pickering CR, Chen Z, Van Waes C. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Rep. 2018 04 03; 23(1):194-212.e6.
PMID:
29617660
; PMCID:
PMC6002769
.
Citations:
107
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Saltz J, Gupta R, Hou L, Kurc T, Singh P, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J, Shmulevich I, Rao AUK,
Lazar AJ
, Sharma A, Thorsson V, Saltz J, Gupta R, Hou L, Kurc T,
Singh P
, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J, Cancer Genome Atlas Research Network, Shmulevich I, Rao AUK, Lazar AJ, Sharma A, Thorsson V, Thorsson V. Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Rep. 2018 04 03; 23(1):181-193.e7.
PMID:
29617659
; PMCID:
PMC5943714
.
Citations:
239
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Gao Q, Liang WW, Foltz SM, Mutharasu G, Jayasinghe RG, Cao S, Liao WW, Reynolds SM, Wyczalkowski MA, Yao L, Yu L, Sun SQ, Chen K, Lazar AJ, Fields RC, Wendl MC, Van Tine BA, Vij R, Chen F, Nykter M, Shmulevich I, Ding L, Gao Q, Liang WW, Foltz SM, Mutharasu G, Jayasinghe RG, Cao S, Liao WW, Reynolds SM, Wyczalkowski MA, Yao L, Yu L, Sun SQ, Fusion Analysis Working Group, Cancer Genome Atlas Research Network, Chen K,
Lazar AJ
, Fields RC, Wendl MC, Van Tine BA, Vij R, Chen F, Nykter M, Shmulevich I, Ding L. Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Rep. 2018 04 03; 23(1):227-238.e3.
PMID:
29617662
; PMCID:
PMC5916809
.
Citations:
152
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ, Cherniack AD, Beroukhim R, Meyerson M, Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J,
Lazar AJ
, Cancer Genome Atlas Research Network, Cherniack AD, Beroukhim R, Meyerson M. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer Cell. 2018 04 09; 33(4):676-689.e3.
PMID:
29622463
; PMCID:
PMC6028190
.
Citations:
285
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W,
Akbani R
, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS,
Lazar AJ
, Sakai R, Thorsson V, Bass AJ, Laird PW, Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Cancer Genome Atlas Research Network, Thorsson V, Bass AJ, Laird PW, Thorsson V. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer Cell. 2018 04 09; 33(4):721-735.e8.
PMID:
29622466
; PMCID:
PMC5966039
.
Citations:
177
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Beird HC, Wu CC, Ingram DR, Wang WL, Alimohamed A, Gumbs C, Little L, Song X,
Feig BW
, Roland CL, Zhang J, Benjamin RS,
Hwu P
, Lazar AJ, Futreal PA,
Somaiah N
, Beird HC, Wu CC, Ingram DR, Wang WL, Alimohamed A, Gumbs C, Little L, Song X, Feig BW,
Roland CL
, Zhang J, Benjamin RS, Hwu P,
Lazar AJ
, Futreal PA, Somaiah N. Genomic profiling of dedifferentiated liposarcoma compared to matched well-differentiated liposarcoma reveals higher genomic complexity and a common origin. Cold Spring Harb Mol Case Stud. 2018 04; 4(2).
PMID:
29610390
; PMCID:
PMC5880260
.
Citations:
22
Fields:
Gen
Genetics
Translation:
Humans
Berger AC, Korkut A, Kanchi RS, Hegde AM, Lenoir W, Liu W, Liu Y, Fan H, Shen H, Ravikumar V, Rao A, Schultz A, Li X, Sumazin P, Williams C, Mestdagh P,
Gunaratne PH
, Yau C, Bowlby R, Robertson AG, Tiezzi DG, Wang C, Cherniack AD, Godwin AK, Kuderer NM, Rader JS, Zuna RE,
Sood AK
, Lazar AJ, Ojesina AI, Adebamowo C, Adebamowo SN,
Baggerly KA
, Chen TW,
Chiu HS
, Lefever S, Liu L, MacKenzie K, Orsulic S, Roszik J, Shelley CS, Song Q, Vellano CP, Wentzensen N,
Weinstein JN
, Mills GB, Levine DA,
Akbani R
, Berger AC,
Korkut A
, Kanchi RS, Hegde AM, Lenoir W, Liu W, Liu Y, Fan H, Shen H, Ravikumar V, Rao A, Schultz A, Li X,
Sumazin P
, Williams C, Mestdagh P, Gunaratne PH, Yau C, Bowlby R, Robertson AG, Tiezzi DG, Wang C, Cherniack AD, Godwin AK, Kuderer NM, Rader JS, Zuna RE, Sood AK,
Lazar AJ
, Ojesina AI, Adebamowo C, Adebamowo SN, Baggerly KA, Chen TW, Chiu HS, Lefever S, Liu L, MacKenzie K, Orsulic S, Roszik J, Shelley CS, Song Q, Vellano CP, Wentzensen N, Cancer Genome Atlas Research Network, Weinstein JN,
Mills GB
, Levine DA, Akbani R, Williams C, Tiezzi DG. A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell. 2018 04 09; 33(4):690-705.e9.
PMID:
29622464
; PMCID:
PMC5959730
.
Citations:
207
Fields:
Neo
Neoplasms
Translation:
Humans
Livingston JA, Wang WL, Tsai JW,
Lazar AJ
, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M,
Gordon NB
,
Kleinerman ES
,
Livingston JA
, Wang WL, Tsai JW, Lazar AJ, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M, Gordon NB, Kleinerman ES. Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol Cancer Ther. 2018 06; 17(6):1315-1323.
PMID:
29592877
; PMCID:
PMC5984702
.
Citations:
9
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
El Beaino M, Roszik J,
Livingston JA
, Wang WL, Lazar AJ,
Amini B
,
Subbiah V
, Lewis V, Conley AP, El Beaino M, Roszik J, Livingston JA, Wang WL,
Lazar AJ
, Amini B, Subbiah V,
Lewis V
,
Conley AP
. Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology. Curr Oncol Rep. 2018 03 26; 20(5):37.
PMID:
29582189
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P,
Lazar AJ
, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC, Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL,
Tsimberidou AM
, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC. Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review. Arch Pathol Lab Med. 2018 10; 142(10):1242-1253.
PMID:
29504834
.
Citations:
36
Fields:
Pat
Pathology
Translation:
Humans
Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P,
Lazar AJ
, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL,
Tsimberidou AM
, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC, Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC. Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review. J Clin Oncol. 2018 06 01; 36(16):1631-1641.
PMID:
29504847
.
Citations:
265
Fields:
Neo
Neoplasms
Translation:
Humans
Romano G, Chen PL, Song P, McQuade JL, Liang RJ, Liu M, Roh W, Duose DY, Carapeto FCL, Li J, Teh JLF, Aplin AE, Chen M, Zhang J, Lazar AJ,
Davies MA
, Futreal PA,
Amaria RN
, Zhang DY, Wargo JA, Kwong LN, Romano G, Chen PL, Song P,
McQuade JL
, Liang RJ, Liu M, Roh W, Duose DY, Carapeto FCL, Li J, Teh JLF, Aplin AE, Chen M, Zhang J,
Lazar AJ
, Davies MA, Futreal PA, Amaria RN, Zhang DY,
Wargo JA
,
Kwong LN
. A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling. Cancer Discov. 2018 05; 8(5):556-567.
PMID:
29496665
; PMCID:
PMC5932238
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Cooper LA, Demicco EG, Saltz JH, Powell RT, Rao A,
Lazar AJ
, Cooper LA, Demicco EG, Saltz JH, Powell RT, Rao A, Lazar AJ. PanCancer insights from The Cancer Genome Atlas: the pathologist's perspective. J Pathol. 2018 04; 244(5):512-524.
PMID:
29288495
; PMCID:
PMC6240356
.
Citations:
56
Fields:
Pat
Pathology
Translation:
Humans
Roland CL
,
Bednarski BK
, Watson K,
Torres KE
,
Cormier JN
, Wang WL,
Lazar AJ
,
Somaiah N
, Hunt KK, Feig BW, Roland CL, Bednarski BK, Watson K, Torres KE, Cormier JN, Wang WL, Lazar AJ, Somaiah N,
Hunt KK
,
Feig BW
. Identification of preoperative factors associated with outcomes following surgical management of intra-abdominal recurrent or metastatic GIST following neoadjuvant tyrosine kinase inhibitor therapy. J Surg Oncol. 2018 Apr; 117(5):879-885.
PMID:
29448300
; PMCID:
PMC5992050
.
Citations:
3
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Amaria RN
, Prieto PA,
Tetzlaff MT
, Reuben A, Andrews MC,
Ross MI
,
Glitza IC
, Cormier J,
Hwu WJ
,
Tawbi HA
,
Patel SP
, Lee JE,
Gershenwald JE
, Spencer CN, Gopalakrishnan V, Bassett R, Simpson L, Mouton R, Hudgens CW, Zhao L, Zhu H, Cooper ZA, Wani K,
Lazar A
,
Hwu P
,
Diab A
, Wong MK, McQuade JL, Royal R, Lucci A, Burton EM, Reddy S, Sharma P, Allison J, Futreal PA,
Woodman SE
,
Davies MA
, Wargo JA, Amaria RN, Prieto PA, Tetzlaff MT, Reuben A, Andrews MC, Ross MI, Glitza IC,
Cormier J
, Hwu WJ, Tawbi HA, Patel SP, Lee JE, Gershenwald JE, Spencer CN, Gopalakrishnan V, Bassett R, Simpson L, Mouton R, Hudgens CW, Zhao L, Zhu H, Cooper ZA, Wani K, Lazar A, Hwu P, Diab A, Wong MK,
McQuade JL
,
Royal R
,
Lucci A
, Burton EM, Reddy S,
Sharma P
,
Allison J
, Futreal PA, Woodman SE, Davies MA,
Wargo JA
. Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial. Lancet Oncol. 2018 02; 19(2):181-193.
PMID:
29361468
.
Citations:
56
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O,
Akbani R
, Bristow CA, Hoadley KA, Iype L, Chang MT, Cherniack AD, Benz C, Mills GB, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC,
Gershenwald JE
, Schoenfield L,
Lazar AJ
, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE,
Esmaeli B
, Kandoth C, Woodman SE, Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O, Akbani R, Bristow CA, Hoadley KA, Iype L, Chang MT, TCGA Research Network, Cherniack AD, Benz C,
Mills GB
, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC, Gershenwald JE, Schoenfield L, Lazar AJ, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE, Esmaeli B, Kandoth C,
Woodman SE
. Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma. Cancer Cell. 2018 01 08; 33(1):151.
PMID:
29316429
.
Citations:
41
Fields:
Neo
Neoplasms
Ali AM, Wang WL,
Lazar AJ
, Ali AM, Wang WL, Lazar AJ. Primary chondro-osseous melanoma (chondrosarcomatous and osteosarcomatous melanoma). J Cutan Pathol. 2018 Feb; 45(2):146-150.
PMID:
29068062
.
Citations:
1
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC,
Hwu WJ
, Patel SP, Woodman SE, Amaria RN, Davies MA,
Gershenwald JE
,
Hwu P
, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA, Gopalakrishnan V, Spencer CN,
Nezi L
, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL,
Shpall EJ
,
Rezvani K
, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J,
Lazar AJ
, Tsujikawa T, Diab A, Tawbi H,
Glitza IC
, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA, Zitvogel L. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science. 2018 01 05; 359(6371):97-103.
PMID:
29097493
; PMCID:
PMC5827966
.
Citations:
1227
Fields:
Sci
Science
Translation:
Humans
Animals
Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S, Lazar AJ,
Pant S
, Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S,
Lazar AJ
, Pant S. Overview of the TREC 2017 Precision Medicine Track. Text Retr Conf. 2017 Nov; 26.
PMID:
32776021
; PMCID:
PMC7410346
.
Citations:
Keung EZ, Tsai JW, Ali AM, Cormier JN,
Bishop AJ
, Guadagnolo BA, Torres KE,
Somaiah N
, Hunt KK,
Wargo JA
,
Lazar AJ
, Wang WL,
Roland CL
, Keung EZ, Tsai JW, Ali AM,
Cormier JN
, Bishop AJ,
Guadagnolo BA
,
Torres KE
, Somaiah N,
Hunt KK
, Wargo JA, Lazar AJ, Wang WL, Roland CL. Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy: Rationale for combination neoadjuvant immune checkpoint inhibition and radiotherapy. Oncoimmunology. 2018; 7(2):e1385689.
PMID:
29308306
; PMCID:
PMC5749668
.
Citations:
19
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Panse G, Chrisinger JS, Leung CH, Ingram DR, Khan S, Wani K, Lin H, Lazar AJ, Wang WL, Panse G, Chrisinger JS, Leung CH, Ingram DR, Khan S, Wani K, Lin H,
Lazar AJ
, Wang WL. Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas. Histopathology. 2018 Jan; 72(2):239-247.
PMID:
28796347
.
Citations:
6
Fields:
Pat
Pathology
Translation:
Humans
Gershenwald JE
, Scolyer RA,
Hess KR
, Sondak VK, Long GV,
Ross MI
, Lazar AJ, Faries MB, Kirkwood JM, McArthur GA, Haydu LE, Eggermont AMM, Flaherty KT,
Balch CM
, Thompson JF, Gershenwald JE, Scolyer RA, Hess KR, Sondak VK, Long GV, Ross MI,
Lazar AJ
, Faries MB,
Kirkwood JM
, McArthur GA, Haydu LE, Eggermont AMM, Flaherty KT, Balch CM, Thompson JF, for members of the American Joint Committee on Cancer Melanoma Expert Panel and the International Me. Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual. CA Cancer J Clin. 2017 Nov; 67(6):472-492.
PMID:
29028110
; PMCID:
PMC5978683
.
Citations:
454
Fields:
Neo
Neoplasms
Translation:
Humans
Nagarajan R, Bartley AN, Bridge JA, Jennings LJ, Kamel-Reid S, Kim A,
Lazar AJ
, Lindeman NI, Moncur J, Rai AJ,
Routbort MJ
, Vasalos P, Merker JD, Nagarajan R, Bartley AN, Bridge JA, Jennings LJ, Kamel-Reid S, Kim A, Lazar AJ, Lindeman NI, Moncur J, Rai AJ, Routbort MJ, Vasalos P, Merker JD. A Window Into Clinical Next-Generation Sequencing-Based Oncology Testing Practices. Arch Pathol Lab Med. 2017 Dec; 141(12):1679-1685.
PMID:
29028368
.
Citations:
7
Fields:
Pat
Pathology
Translation:
Humans
Tawbi HA
, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J,
Lazar AJ
, Wistuba II, Baker LH, Maki RG, Reinke D,
Patel S
, Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ,
Wistuba II
, Baker LH, Maki RG, Reinke D, Patel S. Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial. Lancet Oncol. 2017 11; 18(11):1493-1501.
PMID:
28988646
; PMCID:
PMC7939029
.
Citations:
359
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
May CD, Landers SM, Bolshakov S, Ma X, Ingram DR, Kivlin CM, Watson KL, Sannaa GAA, Bhalla AD, Wang WL, Lazar AJ,
Torres KE
, May CD, Landers SM, Bolshakov S, Ma X, Ingram DR, Kivlin CM, Watson KL, Sannaa GAA, Bhalla AD, Wang WL,
Lazar AJ
, Torres KE. Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma. Cancer Biol Ther. 2017 10 03; 18(10):816-826.
PMID:
29099264
; PMCID:
PMC5678691
.
Citations:
8
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Livingston JA, Bugano D, Barbo A, Lin H, Madewell JE, Wang WL,
Lazar AJ
, Tseng WW, Roland CL,
Feig BW
, Pollock R, Conley AP, Benjamin RS, Patel S, Somaiah N, Livingston JA, Bugano D, Barbo A, Lin H,
Madewell JE
, Wang WL, Lazar AJ, Tseng WW, Roland CL, Feig BW, Pollock R, Conley AP, Benjamin RS, Patel S, Somaiah N, Bugano D. Role of chemotherapy in dedifferentiated liposarcoma of the retroperitoneum: defining the benefit and challenges of the standard. Sci Rep. 2017 09 19; 7(1):11836.
PMID:
28928422
; PMCID:
PMC5605500
.
Citations:
23
Fields:
Sci
Science
Translation:
Humans
Young ED, Ingram D, Metcalf-Doetsch W, Khan D, Al Sannaa G, Le Loarer F, Lazar AJF, Slopis J, Torres KE, Lev D, Pollock RE,
McCutcheon IE
, Young ED, Ingram D, Metcalf-Doetsch W, Khan D, Al Sannaa G, Le Loarer F,
Lazar AJF
,
Slopis J
,
Torres KE
, Lev D, Pollock RE, McCutcheon IE. Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers. J Neurosurg. 2018 09; 129(3):805-814.
PMID:
28885122
.
Citations:
6
Fields:
Neu
Neurosurgery
Translation:
Humans
Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O,
Akbani R
, Bristow CA, Hoadley KA, Iype L, Chang MT, Cherniack AD, Benz C,
Mills GB
, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC,
Gershenwald JE
, Schoenfield L,
Lazar AJ
, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE,
Esmaeli B
, Kandoth C,
Woodman SE
, Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O, Akbani R, Bristow CA, Hoadley KA, Iype L, Chang MT, TCGA Research Network, Cherniack AD, Benz C, Mills GB, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC, Gershenwald JE, Schoenfield L, Lazar AJ, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE, Esmaeli B, Kandoth C, Woodman SE, Walter V, Penson A, Kandoth C. Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma. Cancer Cell. 2017 08 14; 32(2):204-220.e15.
PMID:
28810145
; PMCID:
PMC5619925
.
Citations:
275
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Reuben A, Petaccia de Macedo M, McQuade J, Joon A, Ren Z, Calderone T, Conner B, Wani K, Cooper ZA, Tawbi H, Tetzlaff MT, Padera RF, Durand JB,
Lazar AJ
,
Wargo JA
,
Davies MA
, Reuben A, Petaccia de Macedo M,
McQuade J
, Joon A, Ren Z, Calderone T, Conner B, Wani K, Cooper ZA,
Tawbi H
,
Tetzlaff MT
, Padera RF, Durand JB, Lazar AJ, Wargo JA, Davies MA. Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab. Oncoimmunology. 2017; 6(12):e1361097.
PMID:
29209563
; PMCID:
PMC5706622
.
Citations:
19
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Patel NR, Chrisinger JSA, Demicco EG, Sarabia SF, Reuther J, Kumar E, Oliveira AM, Billings SD, Bovée JVMG, Roy A,
Lazar AJ
,
Lopez-Terrada DH
, Wang WL, Patel NR, Chrisinger JSA, Demicco EG, Sarabia SF, Reuther J, Kumar E, Oliveira AM, Billings SD, Bovée JVMG,
Roy A
, Lazar AJ, Lopez-Terrada DH, Wang WL, Bov?e JVMG. USP6 activation in nodular fasciitis by promoter-swapping gene fusions. Mod Pathol. 2017 11; 30(11):1577-1588.
PMID:
28752842
.
Citations:
24
Fields:
Pat
Pathology
Translation:
Humans
Cells
Demicco EG, Wagner MJ, Maki RG, Gupta V, Iofin I, Lazar AJ, Wang WL, Demicco EG, Wagner MJ, Maki RG, Gupta V, Iofin I,
Lazar AJ
, Wang WL. Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model. Mod Pathol. 2017 10; 30(10):1433-1442.
PMID:
28731041
.
Citations:
56
Fields:
Pat
Pathology
Translation:
Humans
Wagner MJ, Gopalakrishnan V, Ravi V, Livingston JA, Conley AP, Araujo D, Somaiah N, Zarzour MA,
Ratan R
, Wang WL,
Patel SR
,
Lazar A
, Ludwig JA, Benjamin RS, Wagner MJ, Gopalakrishnan V,
Ravi V
, Livingston JA,
Conley AP
,
Araujo D
,
Somaiah N
,
Zarzour MA
, Ratan R, Wang WL, Patel SR, Lazar A,
Ludwig JA
, Benjamin RS. Vincristine, Ifosfamide, and Doxorubicin for Initial Treatment of Ewing Sarcoma in Adults. Oncologist. 2017 10; 22(10):1271-1277.
PMID:
28710342
; PMCID:
PMC5634776
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
O'Rourke A, Humphries K,
Lazar A
, Martin-Harris B, O'Rourke A, Humphries K, Lazar A, Martin-Harris B. The pharyngeal contractile integral is a useful indicator of pharyngeal swallowing impairment. Neurogastroenterol Motil. 2017 Dec; 29(12).
PMID:
28699250
; PMCID:
PMC5690888
.
Citations:
10
Fields:
Gas
Gastroenterology
Neu
Neurology
Translation:
Humans
CT
Clinical Trials
Conley AP, Trinh VA, Zobniw CM, Posey K, Martinez JD, Arrieta OG, Wang WL, Lazar AJ, Somaiah N, Roszik J,
Patel SR
,
Conley AP
, Trinh VA, Zobniw CM, Posey K, Martinez JD, Arrieta OG, Wang WL,
Lazar AJ
,
Somaiah N
, Roszik J, Patel SR. Positive Tumor Response to Combined Checkpoint Inhibitors in a Patient With Refractory Alveolar Soft Part Sarcoma: A Case Report. J Glob Oncol. 2018 09; 4:1-6.
PMID:
30241159
; PMCID:
PMC6180844
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Al-Zaid T, Wang WL, Somaiah N,
Lazar AJ
, Al-Zaid T, Wang WL,
Somaiah N
, Lazar AJ. Molecular profiling of sarcomas: new vistas for precision medicine. Virchows Arch. 2017 Aug; 471(2):243-255.
PMID:
28664413
.
Citations:
2
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Pat
Pathology
Translation:
Humans
de Graaff MA, Malu S, Guardiola I, Kruisselbrink AB, de Jong Y, Corver WE, Gelderblom H, Hwu P, Nielsen TO,
Lazar AJ
, Somaiah N, Bovée JVMG, de Graaff MA, Malu S, Guardiola I, Kruisselbrink AB, de Jong Y, Corver WE, Gelderblom H,
Hwu P
, Nielsen TO, Lazar AJ,
Somaiah N
, Bovée JVMG, Bov?e JVMG. High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth. Transl Oncol. 2017 Aug; 10(4):546-554.
PMID:
28654818
; PMCID:
PMC5487254
.
Citations:
6
Dodd RD, Lee CL, Overton T, Huang W, Eward WC, Luo L, Ma Y, Ingram DR, Torres KE, Cardona DM, Lazar AJ, Kirsch DG, Dodd RD, Lee CL, Overton T, Huang W, Eward WC, Luo L, Ma Y, Ingram DR,
Torres KE
, Cardona DM,
Lazar AJ
, Kirsch DG. NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response. Cancer Res. 2017 08 15; 77(16):4486-4497.
PMID:
28646022
; PMCID:
PMC5839126
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Charville GW, Wang WL, Ingram DR, Roy A, Thomas D, Patel RM, Hornick JL, van de Rijn M,
Lazar AJ
, Charville GW, Wang WL, Ingram DR,
Roy A
, Thomas D, Patel RM, Hornick JL, van de Rijn M, Lazar AJ. EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma. Mod Pathol. 2017 09; 30(9):1312-1320.
PMID:
28643791
.
Citations:
22
Fields:
Pat
Pathology
Translation:
Humans
Cells
Leon-Castillo A, Chrisinger JSA, Panse G, Samdani RT, Ingram DR, Ravi V,
Prieto VG
, Wang WL, Lazar AJ, Leon-Castillo A, Chrisinger JSA, Panse G, Samdani RT, Ingram DR,
Ravi V
, Prieto VG, Wang WL,
Lazar AJ
. Index report of cutaneous angiosarcomas with strong positivity for tyrosinase mimicking melanoma with further evaluation of melanocytic markers in a large angiosarcoma series. J Cutan Pathol. 2017 Aug; 44(8):692-697.
PMID:
28556023
.
Citations:
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Roszik J, Wang WL, Livingston JA,
Roland CL
,
Ravi V
,
Yee C
, Hwu P,
Futreal A
, Lazar AJ, Patel SR,
Conley AP
, Roszik J, Wang WL,
Livingston JA
, Roland CL, Ravi V, Yee C,
Hwu P
, Futreal A,
Lazar AJ
,
Patel SR
, Conley AP. Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes. Clin Sarcoma Res. 2017; 7:11.
PMID:
28630682
; PMCID:
PMC5471883
.
Citations:
19
Gopalakrishnan V,
Amini B
, Wagner MJ, Nowell EN,
Lazar AJ
, Lin PP, Benjamin RS,
Araujo DM
, Gopalakrishnan V, Amini B, Wagner MJ, Nowell EN, Lazar AJ,
Lin PP
, Benjamin RS, Araujo DM. Synovial Sarcoma of the Head and Neck: A Single Institution Review. Sarcoma. 2017; 2017:2016752.
PMID:
28655993
; PMCID:
PMC5474548
.
Citations:
5
Sarkar S, Bristow CA, Dey P,
Rai K
, Perets R, Ramirez-Cardenas A, Malasi S, Huang-Hobbs E, Haemmerle M,
Wu SY
, McGuire M, Protopopov A, Jiang S, Liu JF, Hirsch MS, Chang Q,
Lazar AJ
,
Sood AK
, Drapkin R, DePinho R,
Draetta G
, Chin L, Sarkar S, Bristow CA, Dey P, Rai K, Perets R, Ramirez-Cardenas A, Malasi S,
Huang-Hobbs E
, Haemmerle M, Wu SY, McGuire M, Protopopov A, Jiang S, Liu JF, Hirsch MS, Chang Q, Lazar AJ, Sood AK, Drapkin R,
DePinho R
, Draetta G, Chin L. PRKCI promotes immune suppression in ovarian cancer. Genes Dev. 2017 06 01; 31(11):1109-1121.
PMID:
28698296
; PMCID:
PMC5538434
.
Citations:
25
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Miettinen MM, Antonescu CR, Fletcher CDM, Kim A,
Lazar AJ
, Quezado MM, Reilly KM, Stemmer-Rachamimov A, Stewart DR, Viskochil D, Widemann B, Perry A, Miettinen MM, Antonescu CR, Fletcher CDM, Kim A, Lazar AJ, Quezado MM, Reilly KM, Stemmer-Rachamimov A, Stewart DR, Viskochil D, Widemann B, Perry A. Histopathologic evaluation of atypical neurofibromatous tumors and their transformation into malignant peripheral nerve sheath tumor in patients with neurofibromatosis 1-a consensus overview. Hum Pathol. 2017 09; 67:1-10.
PMID:
28551330
; PMCID:
PMC5628119
.
Citations:
86
Fields:
Pat
Pathology
Translation:
Humans
Cells
Semenova G, Stepanova DS, Dubyk C, Handorf E, Deyev SM,
Lazar AJ
, Chernoff J, Semenova G, Stepanova DS, Dubyk C, Handorf E, Deyev SM, Lazar AJ, Chernoff J. Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis. Oncogene. 2017 09 21; 36(38):5421-5431.
PMID:
28534510
; PMCID:
PMC5608634
.
Citations:
17
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Qin Y, Petaccia de Macedo M, Reuben A, Forget MA,
Haymaker C
, Bernatchez C, Spencer CN, Gopalakrishnan V, Reddy S, Cooper ZA, Fulbright OJ, Ramachandran R, Wahl A, Flores E, Thorsen ST, Tavera RJ, Conrad C, Williams MD,
Tetzlaff MT
, Wang WL, Gombos DS,
Esmaeli B
, Amaria RN, Hwu P, Wargo JA,
Lazar AJ
,
Patel SP
, Qin Y, Petaccia de Macedo M, Reuben A, Forget MA, Haymaker C,
Bernatchez C
, Spencer CN, Gopalakrishnan V, Reddy S, Cooper ZA, Fulbright OJ, Ramachandran R, Wahl A, Flores E, Thorsen ST, Tavera RJ,
Conrad C
, Williams MD, Tetzlaff MT, Wang WL,
Gombos DS
, Esmaeli B,
Amaria RN
,
Hwu P
,
Wargo JA
, Lazar AJ, Patel SP, Forget MA. Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study. Oncoimmunology. 2017; 6(6):e1321187.
PMID:
28680759
; PMCID:
PMC5486182
.
Citations:
21
Fields:
All
Allergy and Immunology
Neo
Neoplasms
El Beaino M,
Araujo DM
,
Lazar AJ
,
Lin PP
, El Beaino M, Araujo DM, Lazar AJ, Lin PP. Synovial Sarcoma: Advances in Diagnosis and Treatment Identification of New Biologic Targets to Improve Multimodal Therapy. Ann Surg Oncol. 2017 Aug; 24(8):2145-2154.
PMID:
28397189
.
Citations:
28
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen PL, Beird HC, Garber HR, Roh W, Wani K, Chen E, Haymaker C, Forget MA, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS,
Nezi L
, Cogdill AP,
Bernatchez C
, Roszik J,
Hwu P
, Woodman SE, Chin L,
Tawbi H
,
Davies MA
,
Gershenwald JE
, Amaria RN,
Glitza IC
,
Diab A
, Patel SP, Hu J, Lee JE, Grimm EA,
Tetzlaff MT
, Lazar AJ, Wistuba II, Clise-Dwyer K,
Carter BW
, Zhang J, Futreal PA,
Sharma P
,
Allison JP
, Cooper ZA,
Wargo JA
, Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen PL, Beird HC,
Garber HR
, Roh W, Wani K, Chen E,
Haymaker C
, Forget MA, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS, Nezi L, Cogdill AP, Bernatchez C, Roszik J, Hwu P,
Woodman SE
, Chin L, Tawbi H, Davies MA, Gershenwald JE,
Amaria RN
, Glitza IC, Diab A,
Patel SP
, Hu J, Lee JE,
Grimm EA
, Tetzlaff MT,
Lazar AJ
,
Wistuba II
, Clise-Dwyer K, Carter BW, Zhang J, Futreal PA, Sharma P, Allison JP, Cooper ZA, Wargo JA, Forget MA. Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma. NPJ Genom Med. 2017; 2.
PMID:
28819565
; PMCID:
PMC5557036
.
Citations:
64
Oba J,
Esmaeli B
, Ellerhorst JA, Lyons GR, Milton DR, Wang WL, Macedo MP, Lazar AJ, Grimm EA,
Chattopadhyay C
, Oba J, Esmaeli B, Ellerhorst JA, Lyons GR, Milton DR, Wang WL, Macedo MP,
Lazar AJ
,
Grimm EA
, Chattopadhyay C, Oba J, Milton DR. Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression. Melanoma Res. 2017 04; 27(2):126-133.
PMID:
28118269
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J, Tetzlaff MT,
Davies MA
,
Gershenwald JE
,
Tawbi H
, Lazar AJ,
Hwu P
, Hwu WJ,
Diab A
,
Glitza IC
, Patel SP, Woodman SE, Amaria RN, Prieto VG, Hu J,
Sharma P
,
Allison JP
, Chin L, Zhang J, Wargo JA, Futreal PA, Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J,
Tetzlaff MT
, Davies MA, Gershenwald JE, Tawbi H,
Lazar AJ
, Hwu P,
Hwu WJ
, Diab A, Glitza IC,
Patel SP
,
Woodman SE
,
Amaria RN
,
Prieto VG
, Hu J, Sharma P, Allison JP, Chin L, Zhang J,
Wargo JA
, Futreal PA. Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance. Sci Transl Med. 2017 03 01; 9(379).
PMID:
28251903
; PMCID:
PMC5819607
.
Citations:
323
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Wang WL, Lazar AJ, Wang WL,
Lazar AJ
. Undifferentiated "round" cell ("Ewing-like") sarcoma: not always so-round nor Ewing-like. Virchows Arch. 2017 04; 470(4):371-372.
PMID:
28191614
.
Citations:
1
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Pat
Pathology
Translation:
Humans
Panse G, Leung CH, Ingram DR, Wani K,
Torres KE
, Lin H, Lazar AJ, Wang WL, Panse G, Leung CH, Ingram DR, Wani K, Torres KE, Lin H,
Lazar AJ
, Wang WL. The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours. Histopathology. 2017 May; 70(6):946-953.
PMID:
27992966
.
Citations:
4
Fields:
Pat
Pathology
Translation:
Humans
Cells
Kim DW, Haydu LE, Joon AY, Bassett RL, Siroy AE, Tetzlaff MT, Routbort MJ, Amaria RN,
Wargo JA
,
McQuade JL
, Kemnade J,
Hwu P
, Woodman SE, Roszik J, Kim KB, Gershenwald JE,
Lazar AJ
, Davies MA, Kim DW, Haydu LE, Joon AY, Bassett RL, Siroy AE,
Tetzlaff MT
,
Routbort MJ
,
Amaria RN
, Wargo JA, McQuade JL,
Kemnade J
, Hwu P,
Woodman SE
, Roszik J, Kim KB,
Gershenwald JE
, Lazar AJ, Davies MA. Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients. Cancer. 2017 04 15; 123(8):1372-1381.
PMID:
27911979
; PMCID:
PMC5384865
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Kumar E, Patel NR, Demicco EG, Bovee JV, Olivera AM, Lopez-Terrada DH, Billings SD, Lazar AJ, Wang WL, Kumar E, Patel NR, Demicco EG, Bovee JV, Olivera AM,
Lopez-Terrada DH
, Billings SD,
Lazar AJ
, Wang WL. Cutaneous nodular fasciitis with genetic analysis: a case series. J Cutan Pathol. 2016 Dec; 43(12):1143-1149.
PMID:
27686647
.
Citations:
5
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Barrott JJ, Kafchinski LA, Jin H, Potter JW, Kannan SD, Kennedy R, Mosbruger T, Wang WL, Tsai JW,
Araujo DM
, Liu T, Capecchi MR,
Lazar AJ
, Jones KB, Barrott JJ, Kafchinski LA, Jin H, Potter JW, Kannan SD, Kennedy R, Mosbruger T, Wang WL, Tsai JW, Araujo DM, Liu T, Capecchi MR, Lazar AJ, Jones KB. Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation. J Exp Med. 2016 12 12; 213(13):2989-3005.
PMID:
27956588
; PMCID:
PMC5154942
.
Citations:
16
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Animals
Cells
Roszik J, Haydu LE,
Hess KR
, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC, Baladandayuthapani V, Tetzlaff MT, Wargo JA, Chen K, Forget MA,
Haymaker CL
, Chen JQ, Meric-Bernstam F,
Eterovic AK
, Shaw KR,
Mills GB
,
Gershenwald JE
, Radvanyi LG,
Hwu P
, Futreal PA,
Gibbons DL
, Lazar AJ,
Bernatchez C
,
Davies MA
, Woodman SE,
Roszik J
, Haydu LE, Hess KR, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC,
Baladandayuthapani V
,
Tetzlaff MT
,
Wargo JA
, Chen K, Forget MA, Haymaker CL, Chen JQ,
Meric-Bernstam F
, Eterovic AK, Shaw KR, Mills GB, Gershenwald JE, Radvanyi LG, Hwu P, Futreal PA, Gibbons DL,
Lazar AJ
, Bernatchez C, Davies MA,
Woodman SE
, Forget MA. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Med. 2016 10 25; 14(1):168.
PMID:
27776519
; PMCID:
PMC5078889
.
Citations:
64
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Charville GW, Varma S, Forgó E, Dumont SN, Zambrano E, Trent JC, Lazar AJ, van de Rijn M, Charville GW, Varma S, Forgó E, Dumont SN, Zambrano E, Trent JC,
Lazar AJ
, van de Rijn M, Charville GW, Forg? E. PAX7 Expression in Rhabdomyosarcoma, Related Soft Tissue Tumors, and Small Round Blue Cell Neoplasms. Am J Surg Pathol. 2016 10; 40(10):1305-15.
PMID:
27526298
.
Citations:
9
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Bird JE
, Morse LJ, Feng L, Wang WL,
Lin PP
, Moon BS,
Lazar AJ
, Satcher RL,
Madewell JE
,
Lewis VO
, Bird JE, Morse LJ, Feng L, Wang WL, Lin PP,
Moon BS
, Lazar AJ,
Satcher RL
, Madewell JE, Lewis VO. Non-Radiographic Risk Factors Differentiating Atypical Lipomatous Tumors from Lipomas. Front Oncol. 2016; 6:197.
PMID:
27713864
; PMCID:
PMC5031604
.
Citations:
6
Al Sannaa G, Watson KL, Olar A, Wang WL,
Fuller GN
, McCutcheon I, Torres KE,
Lazar AJ
, Al Sannaa G, Watson KL, Olar A, Wang WL, Fuller GN,
McCutcheon I
,
Torres KE
, Lazar AJ. Sarcoma Brain Metastases: 28?Years of Experience at a Single Institution. Ann Surg Oncol. 2016 12; 23(Suppl 5):962-967.
PMID:
27646022
.
Citations:
3
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Cleven AH, Al Sannaa GA, Briaire-de Bruijn I, Ingram DR, van de Rijn M, Rubin BP, de Vries MW, Watson KL, Torres KE, Wang WL, van Duinen SG, Hogendoorn PC, Lazar AJ, Bovée JV, Cleven AH, Al Sannaa GA, Briaire-de Bruijn I, Ingram DR, van de Rijn M, Rubin BP, de Vries MW, Watson KL, Torres KE, Wang WL, van Duinen SG, Hogendoorn PC,
Lazar AJ
, Bovée JV, Bov?e JV. Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival. Mod Pathol. 2016 09; 29(9):1113.
PMID:
27573709
.
Citations:
13
Fields:
Pat
Pathology
Lamhamedi-Cherradi SE, Menegaz BA, Ramamoorthy V, Vishwamitra D, Wang Y, Maywald RL, Buford AS,
Fokt I
, Skora S, Wang J, Naing A,
Lazar AJ
, Rohren EM, Daw NC, Subbiah V, Benjamin RS,
Ratan R
, Priebe W, Mikos AG,
Amin HM
, Ludwig JA, Lamhamedi-Cherradi SE, Menegaz BA, Ramamoorthy V, Vishwamitra D, Wang Y, Maywald RL, Buford AS, Fokt I, Skora S, Wang J,
Naing A
, Lazar AJ, Rohren EM, Daw NC,
Subbiah V
, Benjamin RS, Ratan R,
Priebe W
, Mikos AG, Amin HM,
Ludwig JA
. IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma. J Natl Cancer Inst. 2016 12; 108(12).
PMID:
27576731
; PMCID:
PMC5241894
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Chen G,
McQuade JL
, Panka DJ, Hudgens CW, Amin-Mansour A, Mu XJ, Bahl S, Jané-Valbuena J, Wani KM, Reuben A, Creasy CA, Jiang H, Cooper ZA, Roszik J, Bassett RL, Joon AY, Simpson LM, Mouton RD, Glitza IC,
Patel SP
,
Hwu WJ
,
Amaria RN
,
Diab A
, Hwu P,
Lazar AJ
, Wargo JA, Garraway LA, Tetzlaff MT, Sullivan RJ, Kim KB,
Davies MA
, Chen G, McQuade JL, Panka DJ, Hudgens CW, Amin-Mansour A, Mu XJ, Bahl S, Jané-Valbuena J, Wani KM, Reuben A, Creasy CA, Jiang H, Cooper ZA, Roszik J, Bassett RL, Joon AY, Simpson LM, Mouton RD,
Glitza IC
, Patel SP, Hwu WJ, Amaria RN, Diab A,
Hwu P
, Lazar AJ,
Wargo JA
, Garraway LA,
Tetzlaff MT
, Sullivan RJ, Kim KB, Davies MA, Jan?-Valbuena J. Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial. JAMA Oncol. 2016 Aug 01; 2(8):1056-64.
PMID:
27124486
; PMCID:
PMC4982774
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Roland CL, Wang WL, Lazar AJ,
Torres KE
,
Roland CL
, Wang WL,
Lazar AJ
, Torres KE. Myxofibrosarcoma. Surg Oncol Clin N Am. 2016 10; 25(4):775-88.
PMID:
27591498
.
Citations:
22
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Chen PL, Roh W, Reuben A, Cooper ZA, Spencer CN, Prieto PA, Miller JP, Bassett RL, Gopalakrishnan V, Wani K, De Macedo MP, Austin-Breneman JL, Jiang H, Chang Q, Reddy SM, Chen WS, Tetzlaff MT, Broaddus RJ,
Davies MA
,
Gershenwald JE
, Haydu L, Lazar AJ,
Patel SP
,
Hwu P
,
Hwu WJ
,
Diab A
, Glitza IC,
Woodman SE
, Vence LM, Wistuba II, Amaria RN, Kwong LN,
Prieto V
, Davis RE, Ma W, Overwijk WW, Sharpe AH, Hu J, Futreal PA, Blando J,
Sharma P
,
Allison JP
, Chin L, Wargo JA, Chen PL, Roh W, Reuben A, Cooper ZA, Spencer CN, Prieto PA, Miller JP, Bassett RL, Gopalakrishnan V, Wani K, De Macedo MP, Austin-Breneman JL, Jiang H, Chang Q, Reddy SM, Chen WS,
Tetzlaff MT
, Broaddus RJ, Davies MA, Gershenwald JE, Haydu L,
Lazar AJ
, Patel SP, Hwu P, Hwu WJ, Diab A,
Glitza IC
, Woodman SE, Vence LM,
Wistuba II
,
Amaria RN
,
Kwong LN
, Prieto V, Davis RE, Ma W,
Overwijk WW
, Sharpe AH, Hu J, Futreal PA, Blando J, Sharma P, Allison JP, Chin L,
Wargo JA
. Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade. Cancer Discov. 2016 08; 6(8):827-37.
PMID:
27301722
; PMCID:
PMC5082984
.
Citations:
385
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
de Graaff MA, Yu JS, Beird HC, Ingram DR, Nguyen T, Juehui Liu J, Bolshakov S, Szuhai K, Åman P, Torres KE, Lev D, Nielsen TO, Bovée JV, Lazar AJ,
Somaiah N
, de Graaff MA, Yu JS, Beird HC, Ingram DR, Nguyen T, Juehui Liu J, Bolshakov S, Szuhai K, Åman P,
Torres KE
, Lev D, Nielsen TO, Bovée JV,
Lazar AJ
, Somaiah N, Szuhai K, ?man P, Bov?e JV. Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation. Lab Invest. 2016 08; 96(8):885-94.
PMID:
27270875
; PMCID:
PMC4965313
.
Citations:
8
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Animals
Cells
Loghavi S
, Routbort MJ, Patel KP, Luthra R, Wang WL, Broaddus RR,
Davies MA
,
Lazar AJ
, Loghavi S,
Routbort MJ
,
Patel KP
,
Luthra R
, Wang WL,
Broaddus RR
, Davies MA, Lazar AJ. How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments? J Natl Compr Canc Netw. 2016 06; 14(6):787-92.
PMID:
27283170
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
El Beaino M, Araujo DM, Gopalakrishnan V, Lazar AJ,
Lin PP
, El Beaino M,
Araujo DM
, Gopalakrishnan V,
Lazar AJ
, Lin PP. Prognosis of T1 synovial sarcoma depends upon surgery by oncologic surgeons. J Surg Oncol. 2016 Sep; 114(4):490-4.
PMID:
27220538
.
Citations:
4
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Roland CL, Boland GM, Demicco EG, Lusby K, Ingram D, May CD, Kivlin CM, Watson K, Al Sannaa GA, Wang WL, Ravi V, Pollock RE, Lev D, Cormier JN, Hunt KK,
Feig BW
,
Lazar AJ
, Torres KE,
Roland CL
, Boland GM, Demicco EG, Lusby K, Ingram D, May CD, Kivlin CM, Watson K, Al Sannaa GA, Wang WL,
Ravi V
, Pollock RE, Lev D,
Cormier JN
,
Hunt KK
, Feig BW, Lazar AJ,
Torres KE
. Clinical Observations and Molecular Variables of Primary Vascular Leiomyosarcoma. JAMA Surg. 2016 Apr; 151(4):347-54.
PMID:
26629783
; PMCID:
PMC4941943
.
Citations:
9
Fields:
Gen
General Surgery
Translation:
Humans
Cleven AH, Sannaa GA, Briaire-de Bruijn I, Ingram DR, van de Rijn M, Rubin BP, de Vries MW, Watson KL,
Torres KE
, Wang WL, van Duinen SG, Hogendoorn PC,
Lazar AJ
, Bovée JV, Cleven AH, Sannaa GA, Briaire-de Bruijn I, Ingram DR, van de Rijn M, Rubin BP, de Vries MW, Watson KL, Torres KE, Wang WL, van Duinen SG, Hogendoorn PC, Lazar AJ, Bovée JV, Bov?e JV. Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival. Mod Pathol. 2016 06; 29(6):582-90.
PMID:
26990975
; PMCID:
PMC4948583
.
Citations:
63
Fields:
Pat
Pathology
Translation:
Humans
Cells
Roland CL
, May CD, Watson KL, Al Sannaa GA, Dineen SP, Feig R, Landers S, Ingram DR, Wang WL, Guadagnolo BA,
Feig B
, Hunt KK, Cormier JN,
Lazar AJ
,
Torres KE
, Roland CL, May CD, Watson KL, Al Sannaa GA, Dineen SP, Feig R, Landers S, Ingram DR, Wang WL,
Guadagnolo BA
, Feig B,
Hunt KK
,
Cormier JN
, Lazar AJ, Torres KE. Analysis of Clinical and Molecular Factors Impacting Oncologic Outcomes in Undifferentiated Pleomorphic Sarcoma. Ann Surg Oncol. 2016 07; 23(7):2220-8.
PMID:
26847678
; PMCID:
PMC4937623
.
Citations:
15
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Messiou C, Bonvalot S, Gronchi A, Vanel D, Meyer M, Robinson P, Morosi C, Bloem JL, Terrier PH,
Lazar A
, Le Péchoux C, Wardelman E, Winfield JM, Boulet B, Bovée J, Haas RL, Messiou C, Bonvalot S, Gronchi A, Vanel D, Meyer M, Robinson P, Morosi C, Bloem JL, Terrier PH, Lazar A, Le Péchoux C, Wardelman E, Winfield JM, Boulet B, Bovée J, Haas RL, Le P?choux C, Wardelman E, Bov?e J. Evaluation of response after pre-operative radiotherapy in soft tissue sarcomas; the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) and Imaging Group recommendations for radiological examination and reporting with an emphasis on magnetic resonance imaging. Eur J Cancer. 2016 Mar; 56:37-44.
PMID:
26802529
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Roszik J, Wu CJ, Siroy AE,
Lazar AJ
, Davies MA, Woodman SE,
Kwong LN
, Roszik J, Wu CJ, Siroy AE, Lazar AJ,
Davies MA
,
Woodman SE
, Kwong LN. Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression. Sci Rep. 2016 Jan 20; 6:19649.
PMID:
26787600
; PMCID:
PMC4726397
.
Citations:
5
Fields:
Sci
Science
Translation:
Humans
Kattan MW, Hess KR, Amin MB, Lu Y, Moons KG, Gershenwald JE, Gimotty PA, Guinney JH, Halabi S,
Lazar AJ
, Mahar AL, Patel T, Sargent DJ, Weiser MR, Compton C, Kattan MW,
Hess KR
, Amin MB, Lu Y, Moons KG,
Gershenwald JE
, Gimotty PA, Guinney JH, Halabi S, Lazar AJ, Mahar AL, Patel T, Sargent DJ, Weiser MR, Compton C, members of the AJCC Precision Medicine Core. American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine. CA Cancer J Clin. 2016 09; 66(5):370-4.
PMID:
26784705
; PMCID:
PMC4955656
.
Citations:
90
Fields:
Neo
Neoplasms
Translation:
Humans
Maher OM,
Khatua S
, Mukherjee D, Olar A,
Lazar A
, Luthra R, Liu D, Wu J, Ketonen L, Zaky W, Maher OM, Khatua S, Mukherjee D, Olar A, Lazar A, Luthra R, Liu D, Wu J,
Ketonen L
,
Zaky W
. Primary intracranial soft tissue sarcomas in children, adolescents, and young adults: single institution experience and review of the literature. J Neurooncol. 2016 Mar; 127(1):155-63.
PMID:
26718692
; PMCID:
PMC4876035
.
Citations:
1
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Wardelmann E, Haas RL, Bovée JV, Terrier P,
Lazar A
, Messiou C, LePechoux C, Hartmann W, Collin F, Fisher C, Mechtersheimer G, DeiTos AP, Stacchiotti S, Jones RL, Gronchi A, Bonvalot S, Wardelmann E, Haas RL, Bovée JV, Terrier P, Lazar A, Messiou C, LePechoux C, Hartmann W, Collin F, Fisher C, Mechtersheimer G, DeiTos AP, Stacchiotti S, Jones RL, Gronchi A, Bonvalot S, Wardelmann E, Bov?e JV, Hartmann W. Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting. Eur J Cancer. 2016 Jan; 53:84-95.
PMID:
26700077
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Kivlin CM, Watson KL, Al Sannaa GA, Belousov R, Ingram DR, Huang KL, May CD, Bolshakov S, Landers SM, Kalam AA,
Slopis JM
,
McCutcheon IE
, Pollock RE, Lev D,
Lazar AJ
, Torres KE, Kivlin CM, Watson KL, Al Sannaa GA, Belousov R, Ingram DR, Huang KL, May CD, Bolshakov S, Landers SM, Kalam AA, Slopis JM, McCutcheon IE, Pollock RE, Lev D, Lazar AJ,
Torres KE
. Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor. Cancer Biol Ther. 2016; 17(2):129-38.
PMID:
26650448
; PMCID:
PMC4847988
.
Citations:
3
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Peng W
, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R,
Lazar AJ
, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X,
Bernatchez C
, Forget MA,
Haymaker C
, Amaria R, McQuade JL,
Glitza IC
, Cascone T, Li HS,
Kwong LN
, Heffernan TP, Hu J, Bassett RL, Bosenberg MW,
Woodman SE
, Overwijk WW, Lizée G, Roszik J, Gajewski TF,
Wargo JA
,
Gershenwald JE
, Radvanyi L,
Davies MA
,
Hwu P
, Peng W, Chen JQ, Liu C, Malu S, Creasy C,
Tetzlaff MT
, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C,
Amaria R
,
McQuade JL
, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL, Bosenberg MW, Woodman SE,
Overwijk WW
, Lizée G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P, Liz?e G. Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy. Cancer Discov. 2016 Feb; 6(2):202-16.
PMID:
26645196
; PMCID:
PMC4744499
.
Citations:
581
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Verschoor AJ, Cleton-Jansen AM, Wijers-Koster P, Coffin CM, Lazar AJ, Nout RA, Rubin BP, Gelderblom H, Bovée JV, Verschoor AJ, Cleton-Jansen AM, Wijers-Koster P, Coffin CM,
Lazar AJ
, Nout RA, Rubin BP, Gelderblom H, Bovée JV, Verschoor AJ, Bov?e JV. Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor. Am J Surg Pathol. 2015 Dec; 39(12):1701-7.
PMID:
26414222
.
Citations:
1
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Kamali F,
Wang WL
,
Guadagnolo BA
, Fox PS,
Lewis VO
,
Lazar AJ
, Conley AP, Ravi V, Toliyat M, Ladha HS,
Hobbs BP
,
Amini B
, Kamali F, Wang WL, Guadagnolo BA, Fox PS, Lewis VO, Lazar AJ,
Conley AP
,
Ravi V
, Toliyat M, Ladha HS, Hobbs BP, Amini B. MRI may be used as a prognostic indicator in patients with extra-abdominal desmoid tumours. Br J Radiol. 2016; 89(1058):20150308.
PMID:
26577289
; PMCID:
PMC4985189
.
Citations:
6
Fields:
Rad
Radiology
Translation:
Humans
May CD, Garnett J, Ma X, Landers SM, Ingram DR, Demicco EG, Al Sannaa GA, Vu T, Han L, Zhang Y, Kivlin CM, Bolshakov S, Kalam AA, Liu J, Zhou F, Broccoli D, Wang WL,
Lazar AJ
, Pollock RE, Lev D, Torres KE, May CD, Garnett J, Ma X, Landers SM, Ingram DR, Demicco EG, Al Sannaa GA, Vu T, Han L, Zhang Y, Kivlin CM, Bolshakov S, Kalam AA, Liu J, Zhou F, Broccoli D, Wang WL, Lazar AJ, Pollock RE, Lev D,
Torres KE
. AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas. BMC Cancer. 2015 Nov 14; 15:901.
PMID:
26573603
; PMCID:
PMC4647521
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Chinyengetere F, Sekula DJ, Lu Y, Giustini AJ, Sanglikar A, Kawakami M, Ma T, Burkett SS, Eisenberg BL, Wells WA, Hoopes PJ, Demicco EG,
Lazar AJ
,
Torres KE
, Memoli V, Freemantle SJ, Dmitrovsky E, Chinyengetere F, Sekula DJ, Lu Y, Giustini AJ, Sanglikar A, Kawakami M, Ma T, Burkett SS, Eisenberg BL, Wells WA, Hoopes PJ, Demicco EG, Lazar AJ, Torres KE, Memoli V, Freemantle SJ,
Dmitrovsky E
. Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas. BMC Cancer. 2015 Nov 10; 15:886.
PMID:
26555296
; PMCID:
PMC4640382
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Roy-Chowdhuri S, de Melo Gagliato D, Routbort MJ,
Patel KP
, Singh RR, Broaddus R, Lazar AJ,
Sahin A
, Alvarez RH, Moulder S, Wheler JJ,
Janku F
, Gonzalez-Angulo AM, Chavez-MacGregor M, Valero V,
Ueno NT
,
Mills G
, Mendelsohn J, Yao H, Aldape K, Luthra R,
Meric-Bernstam F
, Roy-Chowdhuri S, de Melo Gagliato D,
Routbort MJ
, Patel KP,
Singh RR
,
Broaddus R
,
Lazar AJ
, Sahin A, Alvarez RH,
Moulder S
, Wheler JJ, Janku F, Gonzalez-Angulo AM, Chavez-MacGregor M, Valero V, Ueno NT, Mills G,
Mendelsohn J
, Yao H, Aldape K,
Luthra R
, Meric-Bernstam F. Multigene clinical mutational profiling of breast carcinoma using next-generation sequencing. Am J Clin Pathol. 2015 Nov; 144(5):713-21.
PMID:
26486734
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
Jamshidi F, Bashashati A, Shumansky K, Dickson B, Gokgoz N, Wunder JS, Andrulis IL,
Lazar AJ
, Shah SP, Huntsman DG, Nielsen TO, Jamshidi F, Bashashati A, Shumansky K, Dickson B, Gokgoz N, Wunder JS, Andrulis IL, Lazar AJ, Shah SP, Huntsman DG, Nielsen TO. The genomic landscape of epithelioid sarcoma cell lines and tumours. J Pathol. 2016 Jan; 238(1):63-73.
PMID:
26365879
.
Citations:
21
Fields:
Pat
Pathology
Translation:
Humans
Cells
Bill KL, Garnett J, Meaux I, Ma X, Creighton CJ, Bolshakov S, Barriere C, Debussche L, Lazar AJ, Prudner BC, Casadei L, Braggio D, Lopez G, Zewdu A, Bid H, Lev D, Pollock RE, Bill KL, Garnett J, Meaux I, Ma X,
Creighton CJ
, Bolshakov S, Barriere C, Debussche L,
Lazar AJ
, Prudner BC, Casadei L, Braggio D, Lopez G, Zewdu A, Bid H, Lev D, Pollock RE. SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma. Clin Cancer Res. 2016 Mar 01; 22(5):1150-60.
PMID:
26475335
; PMCID:
PMC4775372
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Rai K
, Akdemir KC, Kwong LN, Fiziev P, Wu CJ, Keung EZ, Sharma S, Samant NS, Williams M, Axelrad JB, Shah A, Yang D, Grimm EA, Barton MC, Milton DR, Heffernan TP, Horner JW,
Ekmekcioglu S
,
Lazar AJ
, Ernst J, Chin L, Rai K, Akdemir KC,
Kwong LN
, Fiziev P, Wu CJ, Keung EZ, Sharma S, Samant NS, Williams M, Axelrad JB, Shah A, Yang D,
Grimm EA
,
Barton MC
, Milton DR, Heffernan TP, Horner JW, Ekmekcioglu S, Lazar AJ, Ernst J, Chin L. Dual Roles of RNF2 in Melanoma Progression. Cancer Discov. 2015 Dec; 5(12):1314-27.
PMID:
26450788
; PMCID:
PMC4670809
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Shang H, Braggio D, Lee YJ, Al Sannaa GA,
Creighton CJ
, Bolshakov S,
Lazar AJ
, Lev D, Pollock RE, Shang H, Braggio D, Lee YJ, Al Sannaa GA, Creighton CJ, Bolshakov S, Lazar AJ, Lev D, Pollock RE. Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors. Cancer. 2015 Nov 15; 121(22):4088-96.
PMID:
26349011
; PMCID:
PMC4635059
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Sholl LM, Andea A, Bridge JA, Cheng L, Davies MA, Ehteshami M, Gangadhar TC, Kamel-Reid S,
Lazar A
, Raparia K, Siroy A, Watson KL, Sholl LM, Andea A, Bridge JA, Cheng L, Davies MA, Ehteshami M, Gangadhar TC, Kamel-Reid S, Lazar A, Raparia K, Siroy A, Watson KL, Members of Cancer Biomarker Reporting Committee, College of American Pathologists. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Melanoma. Arch Pathol Lab Med. 2016 Apr; 140(4):355-7.
PMID:
26340412
.
Citations:
3
Fields:
Pat
Pathology
Translation:
Humans
Jharap B, Sandborn WJ, Reinisch W, D'Haens G, Robinson AM, Wang W, Huang B,
Lazar A
, Thakkar RB, Colombel JF, Jharap B, Sandborn WJ, Reinisch W, D'Haens G, Robinson AM, Wang W, Huang B, Lazar A, Thakkar RB, Colombel JF. Randomised clinical study: discrepancies between patient-reported outcomes and endoscopic appearance in moderate to severe ulcerative colitis. Aliment Pharmacol Ther. 2015 Nov; 42(9):1082-92.
PMID:
26381802
; PMCID:
PMC5049645
.
Citations:
28
Fields:
Dru
Drug Therapy
Gas
Gastroenterology
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Keung EZ, Akdemir KC, Al Sannaa GA, Garnett J, Lev D,
Torres KE
, Lazar AJ,
Rai K
, Chin L, Keung EZ, Akdemir KC, Al Sannaa GA, Garnett J, Lev D, Torres KE,
Lazar AJ
, Rai K, Chin L. Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma. J Clin Invest. 2015 Aug 03; 125(8):2965-78.
PMID:
26193637
; PMCID:
PMC4563740
.
Citations:
15
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Tseng WW, Zhou S, To CA,
Thall PF
, Lazar AJ, Pollock RE,
Lin PP
,
Cormier JN
,
Lewis VO
,
Feig BW
, Hunt KK, Ballo MT,
Patel S
, Pisters PW, Tseng WW, Zhou S, To CA, Thall PF,
Lazar AJ
, Pollock RE, Lin PP, Cormier JN, Lewis VO, Feig BW,
Hunt KK
, Ballo MT, Patel S, Pisters PW. Phase 1 adaptive dose-finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high-risk extremity and trunk soft tissue sarcoma. Cancer. 2015 Oct 15; 121(20):3659-67.
PMID:
26177983
; PMCID:
PMC4777348
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Wang WL, Torres-Cabala C, Curry JL,
Ivan D
, McLemore M,
Tetzlaff M
, Zembowicz A,
Prieto VG
, Lazar AJ, Wang WL, Torres-Cabala C,
Curry JL
, Ivan D, McLemore M, Tetzlaff M, Zembowicz A, Prieto VG,
Lazar AJ
, Wang WL. Metastatic atypical fibroxanthoma: a series of 11 cases including with minimal and no subcutaneous involvement. Am J Dermatopathol. 2015 Jun; 37(6):455-61.
PMID:
25590287
.
Citations:
4
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Bill KL, Garnett J, Ma X, May CD, Bolshakov S, Lazar AJ, Lev DC, Pollock RE, Bill KL, Garnett J, Ma X, May CD, Bolshakov S,
Lazar AJ
, Lev DC, Pollock RE. The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma. Lab Invest. 2015 Aug; 95(8):951-61.
PMID:
26006023
; PMCID:
PMC4520775
.
Citations:
7
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Animals
Cells
Patel NR, Salim AA, Sayeed H, Sarabia SF, Hollingsworth F, Warren M, Jakacky J, Tanas M, Oliveira AM, Rubin BP, Lazar AJ, López-Terrada D,
Wang WL
, Patel NR, Salim AA, Sayeed H, Sarabia SF, Hollingsworth F, Warren M, Jakacky J, Tanas M, Oliveira AM, Rubin BP,
Lazar AJ
, López-Terrada D, Wang WL, L?pez-Terrada D. Molecular characterization of epithelioid haemangioendotheliomas identifies novel WWTR1-CAMTA1 fusion variants. Histopathology. 2015 Nov; 67(5):699-708.
PMID:
25817592
.
Citations:
15
Fields:
Pat
Pathology
Translation:
Humans
Tetzlaff MT
, Pattanaprichakul P, Wargo J, Fox PS, Patel KP, Estrella JS, Broaddus RR, Williams MD, Davies MA,
Routbort MJ
,
Lazar AJ
,
Woodman SE
, Hwu WJ, Gershenwald JE,
Prieto VG
, Torres-Cabala CA,
Curry JL
, Tetzlaff MT, Pattanaprichakul P,
Wargo J
, Fox PS,
Patel KP
,
Estrella JS
,
Broaddus RR
, Williams MD,
Davies MA
, Routbort MJ, Lazar AJ, Woodman SE,
Hwu WJ
,
Gershenwald JE
, Prieto VG, Torres-Cabala CA, Curry JL. Utility of BRAF V600E Immunohistochemistry Expression Pattern as a Surrogate of BRAF Mutation Status in 154 Patients with Advanced Melanoma. Hum Pathol. 2015 Aug; 46(8):1101-10.
PMID:
26058727
; PMCID:
PMC4515190
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
Demicco EG, Harms PW, Patel RM, Smith SC, Ingram D, Torres K, Carskadon SL, Camelo-Piragua S, McHugh JB, Siddiqui J, Palanisamy N, Lucas DR,
Lazar AJ
, Wang WL, Demicco EG, Harms PW, Patel RM, Smith SC, Ingram D,
Torres K
, Carskadon SL, Camelo-Piragua S, McHugh JB, Siddiqui J, Palanisamy N, Lucas DR, Lazar AJ, Wang WL. Extensive survey of STAT6 expression in a large series of mesenchymal tumors. Am J Clin Pathol. 2015 May; 143(5):672-82.
PMID:
25873501
; PMCID:
PMC4505928
.
Citations:
53
Fields:
Pat
Pathology
Translation:
Humans
Cells
Demicco EG, Wani K, Fox PS, Bassett RL, Young ED, Lev D, Aldape KD,
Lazar AJ
, Wang WL, Demicco EG, Wani K, Fox PS, Bassett RL, Young ED, Lev D, Aldape KD, Lazar AJ, Wang WL. Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations. Hum Pathol. 2015 Jul; 46(7):1015-26.
PMID:
25976141
.
Citations:
10
Fields:
Pat
Pathology
Translation:
Humans
Cells
Stockman DL, Curry JL, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L, Patel KP, Luthra R,
Davies MA
,
Wargo JA
,
Routbort MA
, Broaddus RR,
Prieto VG
,
Lazar AJ
,
Tetzlaff MT
, Stockman DL,
Curry JL
, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L,
Patel KP
,
Luthra R
, Davies MA, Wargo JA, Routbort MA,
Broaddus RR
, Prieto VG, Lazar AJ, Tetzlaff MT. Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations. J Cutan Pathol. 2015 May; 42(5):308-17.
PMID:
25754356
.
Citations:
6
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Zhang P, Yang X, Ma X, Ingram DR, Lazar AJ,
Torres KE
, Pollock RE, Zhang P, Yang X, Ma X, Ingram DR,
Lazar AJ
, Torres KE, Pollock RE. Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway. Mol Cancer. 2015 Mar 07; 14:55.
PMID:
25890085
; PMCID:
PMC4357176
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Dineen SP,
Roland CL
, Feig R, May C,
Zhou S
, Demicco E, Sannaa GA, Ingram D, Wang WL, Ravi V, Guadagnolo A, Lev D, Pollock RE,
Hunt K
,
Cormier J
,
Lazar A
,
Feig B
, Torres KE, Dineen SP, Roland CL, Feig R, May C, Zhou S, Demicco E, Sannaa GA, Ingram D, Wang WL,
Ravi V
, Guadagnolo A, Lev D, Pollock RE, Hunt K, Cormier J, Lazar A, Feig B,
Torres KE
. Radiation-Associated Undifferentiated Pleomorphic Sarcoma is Associated with Worse Clinical Outcomes than Sporadic Lesions. Ann Surg Oncol. 2015 Nov; 22(12):3913-20.
PMID:
25743327
; PMCID:
PMC4561200
.
Citations:
20
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Hameed M, Corless C, George S, Hornick JL, Kakar S,
Lazar AJ
, Tang L, Hameed M, Corless C, George S, Hornick JL, Kakar S, Lazar AJ, Tang L, Members of the Cancer Biomarker Reporting Committee, College of American Pathologists. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Gastrointestinal Stromal Tumors. Arch Pathol Lab Med. 2015 Oct; 139(10):1271-5.
PMID:
25729899
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Goswami RS,
Patel KP
, Singh RR,
Meric-Bernstam F
, Kopetz ES,
Subbiah V
, Alvarez RH,
Davies MA
, Jabbar KJ, Roy-Chowdhuri S,
Lazar AJ
,
Medeiros LJ
,
Broaddus RR
, Luthra R, Routbort MJ, Goswami RS, Patel KP, Singh RR, Meric-Bernstam F,
Kopetz ES
, Subbiah V, Alvarez RH, Davies MA, Jabbar KJ, Roy-Chowdhuri S, Lazar AJ, Medeiros LJ, Broaddus RR,
Luthra R
,
Routbort MJ
. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clin Cancer Res. 2015 Jun 01; 21(11):2644-51.
PMID:
25695693
; PMCID:
PMC5015593
.
Citations:
41
Fields:
Neo
Neoplasms
Translation:
Humans
Romeo S, Rossi S, Acosta Marín M, Canal F, Sbaraglia M, Laurino L, Mazzoleni G, Montesco MC, Valori L, Campo Dell'Orto M, Gianatti A, Lazar AJ, Dei Tos AP, Romeo S, Rossi S, Acosta Marín M, Canal F, Sbaraglia M, Laurino L, Mazzoleni G, Montesco MC, Valori L, Campo Dell'Orto M, Gianatti A,
Lazar AJ
, Dei Tos AP, Acosta Mar?n M. Primary Synovial Sarcoma (SS) of the digestive system: a molecular and clinicopathological study of fifteen cases. Clin Sarcoma Res. 2015; 5:7.
PMID:
25699170
; PMCID:
PMC4333262
.
Citations:
15
Demicco EG, Boland GM, Brewer Savannah KJ, Lusby K, Young ED, Ingram D, Watson KL, Bailey M, Guo X, Hornick JL, van de Rijn M,
Wang WL
,
Torres KE
, Lev D, Lazar AJ, Demicco EG, Boland GM, Brewer Savannah KJ, Lusby K, Young ED, Ingram D, Watson KL, Bailey M, Guo X, Hornick JL, van de Rijn M, Wang WL, Torres KE, Lev D,
Lazar AJ
. Progressive loss of myogenic differentiation in leiomyosarcoma has prognostic value. Histopathology. 2015 Apr; 66(5):627-38.
PMID:
24889065
; PMCID:
PMC4248015
.
Citations:
12
Fields:
Pat
Pathology
Translation:
Humans
Zhao S, Kurenbekova L, Gao Y, Roos A,
Creighton CJ
, Rao P, Hicks J, Man TK, Lau C, Brown AM, Jones SN, Lazar AJ, Ingram D, Lev D, Donehower LA,
Yustein JT
, Zhao S, Kurenbekova L, Gao Y, Roos A, Creighton CJ, Rao P, Hicks J,
Man TK
, Lau C, Brown AM, Jones SN,
Lazar AJ
, Ingram D, Lev D,
Donehower LA
, Yustein JT. NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma. Oncogene. 2015 Sep 24; 34(39):5069-79.
PMID:
25579177
; PMCID:
PMC4802362
.
Citations:
57
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Animals
Cells
Gong L, Govan JM, Evans EB, Dai H, Wang E, Lee SW, Lin HK, Lazar AJ,
Mills GB
,
Lin SY
, Gong L, Govan JM, Evans EB, Dai H, Wang E, Lee SW, Lin HK,
Lazar AJ
, Mills GB, Lin SY. Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure. Cell Cycle. 2015; 14(14):2323-32.
PMID:
25946202
; PMCID:
PMC4614552
.
Citations:
27
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Zutter MM, Bloom KJ, Cheng L, Hagemann IS, Kaufman JH, Krasinskas AM, Lazar AJ, Leonard DG, Lindeman NI, Moyer AM, Nikiforova MN, Nowak JA, Pfeifer JD, Sepulveda AR, Willis JE, Yohe SL, Zutter MM, Bloom KJ, Cheng L, Hagemann IS, Kaufman JH, Krasinskas AM,
Lazar AJ
, Leonard DG, Lindeman NI, Moyer AM, Nikiforova MN, Nowak JA, Pfeifer JD, Sepulveda AR, Willis JE, Yohe SL. The Cancer Genomics Resource List 2014. Arch Pathol Lab Med. 2015 Aug; 139(8):989-1008.
PMID:
25436904
.
Citations:
9
Fields:
Pat
Pathology
Translation:
Humans
Endo M, de Graaff MA, Ingram DR, Lim S, Lev DC, Briaire-de Bruijn IH,
Somaiah N
, Bovée JV, Lazar AJ, Nielsen TO, Endo M, de Graaff MA, Ingram DR, Lim S, Lev DC, Briaire-de Bruijn IH, Somaiah N, Bovée JV,
Lazar AJ
, Nielsen TO, Bov?e JV. NY-ESO-1 (CTAG1B) expression in mesenchymal tumors. Mod Pathol. 2015 Apr; 28(4):587-95.
PMID:
25412843
.
Citations:
36
Fields:
Pat
Pathology
Translation:
Humans
Peters TL, Kumar V, Polikepahad S, Lin FY, Sarabia SF, Liang Y, Wang WL, Lazar AJ, Doddapaneni H, Chao H, Muzny DM,
Wheeler DA
, Okcu MF, Plon SE, Hicks MJ, López-Terrada D,
Parsons DW
,
Roy A
, Peters TL, Kumar V, Polikepahad S, Lin FY, Sarabia SF, Liang Y, Wang WL,
Lazar AJ
, Doddapaneni H, Chao H,
Muzny DM
, Wheeler DA,
Okcu MF
,
Plon SE
, Hicks MJ, López-Terrada D, Parsons DW, Roy A, L?pez-Terrada D. BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children. Mod Pathol. 2015 Apr; 28(4):575-86.
PMID:
25360585
; PMCID:
PMC4385430
.
Citations:
37
Fields:
Pat
Pathology
Translation:
Humans
Ingram DR, Dillon LM, Lev DC, Lazar A, Demicco EG, Eisenberg BL, Miller TW, Ingram DR, Dillon LM, Lev DC,
Lazar A
, Demicco EG, Eisenberg BL, Miller TW. Estrogen receptor alpha and androgen receptor are commonly expressed in well-differentiated liposarcoma. BMC Clin Pathol. 2014; 14:42.
PMID:
25349530
; PMCID:
PMC4209467
.
Citations:
4
Hughes DP, Kummar S,
Lazar AJ
, Hughes DP, Kummar S, Lazar AJ. New, tolerable ?-secretase inhibitor takes desmoid down a notch. Clin Cancer Res. 2015 Jan 01; 21(1):7-9.
PMID:
25336699
; PMCID:
PMC4306586
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Hwang JA, Yang HM, Hong DP, Joo SY, Choi YL, Park JH, Lazar AJ, Pollock RE, Lev D, Kim SJ, Hwang JA, Yang HM, Hong DP, Joo SY, Choi YL, Park JH,
Lazar AJ
, Pollock RE, Lev D, Kim SJ. Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma. Oncotarget. 2014 Oct 15; 5(19):9065-78.
PMID:
25238053
; PMCID:
PMC4253419
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Bucheit AD, Chen G, Siroy A,
Tetzlaff M
, Broaddus R, Milton D, Fox P, Bassett R,
Hwu P
,
Gershenwald JE
, Lazar AJ,
Davies MA
, Bucheit AD, Chen G, Siroy A, Tetzlaff M,
Broaddus R
, Milton D, Fox P, Bassett R, Hwu P, Gershenwald JE,
Lazar AJ
, Davies MA. Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations. Clin Cancer Res. 2014 Nov 01; 20(21):5527-36.
PMID:
25165098
; PMCID:
PMC4216767
.
Citations:
66
Fields:
Neo
Neoplasms
Translation:
Humans
Siroy AE, Boland GM, Milton DR, Roszik J, Frankian S, Malke J, Haydu L, Prieto VG,
Tetzlaff M
,
Ivan D
, Wang WL, Torres-Cabala C, Curry J, Roy-Chowdhuri S, Broaddus R,
Rashid A
, Stewart J,
Gershenwald JE
, Amaria RN,
Patel SP
, Papadopoulos NE, Bedikian A,
Hwu WJ
,
Hwu P
,
Diab A
,
Woodman SE
, Aldape KD, Luthra R, Patel KP, Shaw KR,
Mills GB
, Mendelsohn J,
Meric-Bernstam F
, Kim KB, Routbort MJ, Lazar AJ,
Davies MA
, Siroy AE, Boland GM, Milton DR, Roszik J, Frankian S, Malke J, Haydu L,
Prieto VG
, Tetzlaff M, Ivan D, Wang WL, Torres-Cabala C,
Curry J
, Roy-Chowdhuri S,
Broaddus R
, Rashid A, Stewart J, Gershenwald JE,
Amaria RN
, Patel SP, Papadopoulos NE, Bedikian A, Hwu WJ, Hwu P, Diab A, Woodman SE, Aldape KD,
Luthra R
,
Patel KP
, Shaw KR, Mills GB,
Mendelsohn J
, Meric-Bernstam F, Kim KB,
Routbort MJ
,
Lazar AJ
, Davies MA, Milton DR. Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma. J Invest Dermatol. 2015 Feb; 135(2):508-515.
PMID:
25148578
; PMCID:
PMC4289407
.
Citations:
56
Fields:
Der
Dermatology
Translation:
Humans
Wolf D, D'Haens G, Sandborn WJ, Colombel JF, Van Assche G, Robinson AM, Lazar A, Zhou Q, Petersson J, Thakkar RB, Wolf D, D'Haens G, Sandborn WJ, Colombel JF, Van Assche G, Robinson AM,
Lazar A
, Zhou Q, Petersson J, Thakkar RB. Escalation to weekly dosing recaptures response in adalimumab-treated patients with moderately to severely active ulcerative colitis. Aliment Pharmacol Ther. 2014 Sep; 40(5):486-97.
PMID:
25041859
.
Citations:
19
Fields:
Dru
Drug Therapy
Gas
Gastroenterology
Pha
Pharmacology
Translation:
Humans
Gontarz M, Wyszynska-Pawelec G, Zapala J, Czopek J, Lazar A, Tomaszewska R, Gontarz M, Wyszynska-Pawelec G, Zapala J, Czopek J,
Lazar A
, Tomaszewska R. Proliferative index activity in oral squamous cell carcinoma: indication for postoperative radiotherapy? Int J Oral Maxillofac Surg. 2014 Oct; 43(10):1189-94.
PMID:
24814691
.
Citations:
1
Fields:
Den
Dentistry
Gen
General Surgery
Translation:
Humans
Chen G, Chakravarti N, Aardalen K, Lazar AJ,
Tetzlaff MT
, Wubbenhorst B, Kim SB, Kopetz S, Ledoux AA, Gopal YN, Pereira CG, Deng W,
Lee JS
, Nathanson KL, Aldape KD,
Prieto VG
, Stuart D,
Davies MA
, Chen G, Chakravarti N, Aardalen K,
Lazar AJ
, Tetzlaff MT, Wubbenhorst B, Kim SB,
Kopetz S
, Ledoux AA, Gopal YN, Pereira CG, Deng W, Lee JS, Nathanson KL, Aldape KD, Prieto VG, Stuart D, Davies MA. Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target. Clin Cancer Res. 2014 Nov 01; 20(21):5537-46.
PMID:
24803579
; PMCID:
PMC4216765
.
Citations:
70
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tseng WW,
Madewell JE
, Wei W,
Somaiah N
, Lazar AJ, Ghadimi MP, Hoffman A, Pisters PW, Lev DC, Pollock RE, Tseng WW, Madewell JE, Wei W, Somaiah N,
Lazar AJ
, Ghadimi MP, Hoffman A, Pisters PW, Lev DC, Pollock RE. Locoregional disease patterns in well-differentiated and dedifferentiated retroperitoneal liposarcoma: implications for the extent of resection? Ann Surg Oncol. 2014 Jul; 21(7):2136-43.
PMID:
24705628
.
Citations:
33
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Shaker M, Pascarelli KM, Plantinga MJ, Love MA,
Lazar AJ
, Ingram DR, von Mehren M, Lev D, Kipling D, Broccoli D, Shaker M, Pascarelli KM, Plantinga MJ, Love MA, Lazar AJ, Ingram DR, von Mehren M, Lev D, Kipling D, Broccoli D. Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas. Biomark Cancer. 2014; 6:1-10.
PMID:
24741338
; PMCID:
PMC3981480
.
Citations:
1
Bednarski BK
,
Araujo DM
, Yi M,
Torres KE
,
Lazar A
, Trent JC,
Cormier JN
, Pisters PW, Lev DC, Pollock RE,
Feig BW
, Hunt KK, Bednarski BK, Araujo DM, Yi M, Torres KE, Lazar A, Trent JC, Cormier JN, Pisters PW, Lev DC, Pollock RE, Feig BW,
Hunt KK
. Analysis of prognostic factors impacting oncologic outcomes after neoadjuvant tyrosine kinase inhibitor therapy for gastrointestinal stromal tumors. Ann Surg Oncol. 2014 Aug; 21(8):2499-505.
PMID:
24639192
; PMCID:
PMC4524653
.
Citations:
13
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Abadin SS, Ayala-Ramirez M, Jimenez C, Dickson PV, Liang Y,
Lazar AJ
, Hornick JL, Cotton M, Sui D, Rich T,
Lee JE
, Grubbs E,
Perrier ND
, Abadin SS, Ayala-Ramirez M,
Jimenez C
, Dickson PV, Liang Y, Lazar AJ, Hornick JL, Cotton M, Sui D, Rich T, Lee JE,
Grubbs E
, Perrier ND. Impact of surgical resection for subdiaphragmatic paragangliomas. World J Surg. 2014 Mar; 38(3):733-41.
PMID:
24390286
.
Citations:
1
Fields:
Gen
General Surgery
Translation:
Humans
Zhang P, Garnett J,
Creighton CJ
, Al Sannaa GA, Igram DR, Lazar A, Liu X, Liu C, Pollock RE, Zhang P, Garnett J, Creighton CJ, Al Sannaa GA, Igram DR,
Lazar A
, Liu X, Liu C, Pollock RE. EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis. J Pathol. 2014 Feb; 232(3):308-18.
PMID:
24132643
; PMCID:
PMC4166508
.
Citations:
32
Fields:
Pat
Pathology
Translation:
Humans
Animals
Cells
Wang S, Liu CH, Zakharov VP, Lazar AJ, Pollock RE, Larin KV, Wang S, Liu CH, Zakharov VP,
Lazar AJ
, Pollock RE,
Larin KV
. Three-dimensional computational analysis of optical coherence tomography images for the detection of soft tissue sarcomas. J Biomed Opt. 2014 Feb; 19(2):21102.
PMID:
23807552
.
Citations:
14
Fields:
Bio
Biomedical Engineering
Oph
Ophthalmology
Translation:
Humans
Al-Zaid T, Somaiah N,
Lazar AJ
, Al-Zaid T,
Somaiah N
, Lazar AJ. Targeted therapies for sarcomas: new roles for the pathologist. Histopathology. 2014 Jan; 64(1):119-33.
PMID:
24117526
.
Citations:
4
Fields:
Pat
Pathology
Translation:
Humans
Yang J, Du X, Wang G, Sun Y, Chen K, Zhu X,
Lazar AJ
, Hunt KK, Pollock RE, Zhang W, Yang J, Du X, Wang G, Sun Y, Chen K, Zhu X, Lazar AJ,
Hunt KK
, Pollock RE, Zhang W. Mesenchymal to epithelial transition in sarcomas. Eur J Cancer. 2014 Feb; 50(3):593-601.
PMID:
24291235
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Ramakrishnan R, Chaudhry IH, Ramdial P, Lazar AJ, McMenamin ME, Kazakov D, Brenn T, Calonje E, Ramakrishnan R, Chaudhry IH, Ramdial P,
Lazar AJ
, McMenamin ME, Kazakov D, Brenn T, Calonje E, Ramakrishnan R. Primary cutaneous adenoid cystic carcinoma: a clinicopathologic and immunohistochemical study of 27 cases. Am J Surg Pathol. 2013 Oct; 37(10):1603-11.
PMID:
24025525
.
Citations:
19
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Stockman DL, Hornick JL, Deavers MT, Lev DC, Lazar AJ,
Wang WL
, Stockman DL, Hornick JL, Deavers MT, Lev DC,
Lazar AJ
, Wang WL. ERG and FLI1 protein expression in epithelioid sarcoma. Mod Pathol. 2014 Apr; 27(4):496-501.
PMID:
24072183
.
Citations:
12
Fields:
Pat
Pathology
Translation:
Humans
Cells
Bowles DW, Ma WW, Senzer N, Brahmer JR, Adjei AA,
Davies M
, Lazar AJ, Vo A, Peterson S, Walker L, Hausman D, Rudin CM, Jimeno A, Bowles DW, Ma WW, Senzer N, Brahmer JR, Adjei AA, Davies M,
Lazar AJ
, Vo A, Peterson S, Walker L, Hausman D, Rudin CM, Jimeno A. A multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours. Br J Cancer. 2013 Sep 03; 109(5):1085-92.
PMID:
23942080
; PMCID:
PMC3778312
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Bucheit AD, Syklawer E, Jakob JA, Bassett RL, Curry JL,
Gershenwald JE
, Kim KB,
Hwu P
, Lazar AJ,
Davies MA
, Bucheit AD, Syklawer E, Jakob JA, Bassett RL,
Curry JL
, Gershenwald JE, Kim KB, Hwu P,
Lazar AJ
, Davies MA. Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma. Cancer. 2013 Nov 01; 119(21):3821-9.
PMID:
23922205
.
Citations:
40
Fields:
Neo
Neoplasms
Translation:
Humans
Colombo C, Miceli R, Lazar AJ, Perrone F, Pollock RE, Le Cesne A, Hartgrink HH, Cleton-Jansen AM, Domont J, Bovée JV, Bonvalot S, Lev D, Gronchi A, Colombo C, Miceli R,
Lazar AJ
, Perrone F, Pollock RE, Le Cesne A, Hartgrink HH, Cleton-Jansen AM, Domont J, Bovée JV, Bonvalot S, Lev D, Gronchi A, Bov?e JV. CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study. Cancer. 2013 Oct 15; 119(20):3696-702.
PMID:
23913621
.
Citations:
54
Fields:
Neo
Neoplasms
Translation:
Humans
Kim KB,
Cabanillas ME
, Lazar AJ, Williams MD, Sanders DL, Ilagan JL, Nolop K, Lee RJ, Sherman SI, Kim KB, Cabanillas ME,
Lazar AJ
,
Williams MD
, Sanders DL, Ilagan JL, Nolop K, Lee RJ,
Sherman SI
. Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation. Thyroid. 2013 Oct; 23(10):1277-83.
PMID:
23489023
; PMCID:
PMC3967415
.
Citations:
85
Fields:
End
Endocrinology
Translation:
Humans
CT
Clinical Trials
Fitzgibbons PL, Lazar AJ, Spencer S, Fitzgibbons PL,
Lazar AJ
, Spencer S. Introducing new College of American Pathologists reporting templates for cancer biomarkers. Arch Pathol Lab Med. 2014 Feb; 138(2):157-8.
PMID:
23808404
.
Citations:
3
Fields:
Pat
Pathology
Translation:
Humans
Kluk MJ, Ashworth T, Wang H, Knoechel B, Mason EF, Morgan EA, Dorfman D, Pinkus G, Weigert O, Hornick JL, Chirieac LR, Hirsch M, Oh DJ, South AP, Leigh IM, Pourreyron C, Cassidy AJ, Deangelo DJ, Weinstock DM, Krop IE, Dillon D, Brock JE,
Lazar AJ
, Peto M, Cho RJ, Stoeck A, Haines BB, Sathayanrayanan S, Rodig S, Aster JC, Kluk MJ, Ashworth T, Wang H, Knoechel B, Mason EF, Morgan EA, Dorfman D, Pinkus G, Weigert O, Hornick JL, Chirieac LR, Hirsch M, Oh DJ, South AP, Leigh IM, Pourreyron C, Cassidy AJ, Deangelo DJ, Weinstock DM, Krop IE, Dillon D, Brock JE, Lazar AJ, Peto M, Cho RJ, Stoeck A, Haines BB, Sathayanrayanan S, Rodig S, Aster JC. Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. PLoS One. 2013; 8(6):e67306.
PMID:
23825651
; PMCID:
PMC3688991
.
Citations:
51
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Rao P
, Lahat G, Arnold C, Gavino AC, Lahat S, Hornick JL, Lev D,
Lazar AJ
, Rao P, Lahat G, Arnold C, Gavino AC, Lahat S, Hornick JL, Lev D, Lazar AJ. Angiosarcoma: a tissue microarray study with diagnostic implications. Am J Dermatopathol. 2013 Jun; 35(4):432-7.
PMID:
23689692
.
Citations:
14
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Lee N,
Luthra R
,
Lopez-Terrada D
,
Wang WL
,
Lazar AJ
, Lee N, Luthra R, Lopez-Terrada D, Wang WL, Lazar AJ. Retroperitoneal undifferentiated pleomorphic sarcoma having microsatellite instability associated with Muir-Torre syndrome: case report and review of literature. J Cutan Pathol. 2013 Aug; 40(8):730-3.
PMID:
23672746
.
Citations:
3
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Zhang Y, Young ED, Bill K, Belousov R, Peng T, Lazar AJ, Pollock RE, Simmons PJ, Lev D, Kolonin MG, Zhang Y, Young ED, Bill K, Belousov R, Peng T,
Lazar AJ
, Pollock RE, Simmons PJ, Lev D, Kolonin MG. Heterogeneity and immunophenotypic plasticity of malignant cells in human liposarcomas. Stem Cell Res. 2013 Sep; 11(2):772-81.
PMID:
23770802
; PMCID:
PMC3737386
.
Citations:
8
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Park MS, Ravi V,
Conley A
, Patel SR, Trent JC, Lev DC, Lazar AJ, Wang WL, Benjamin RS,
Araujo DM
, Park MS,
Ravi V
, Conley A,
Patel SR
, Trent JC, Lev DC,
Lazar AJ
, Wang WL, Benjamin RS, Araujo DM. The role of chemotherapy in advanced solitary fibrous tumors: a retrospective analysis. Clin Sarcoma Res. 2013 May 11; 3(1):7.
PMID:
23663788
; PMCID:
PMC3660184
.
Citations:
28
Tseng WW,
Somaiah N
,
Lazar AJ
, Lev DC, Pollock RE, Tseng WW, Somaiah N, Lazar AJ, Lev DC, Pollock RE. Novel systemic therapies in advanced liposarcoma: a review of recent clinical trial results. Cancers (Basel). 2013 May 10; 5(2):529-49.
PMID:
24216990
; PMCID:
PMC3730323
.
Citations:
24
Al-Zaid T,
Wang WL
,
Lopez-Terrada D
, Lev D, Hornick JL, Hafeez Diwan A, Fletcher CD,
Lazar AJ
, Al-Zaid T, Wang WL, Lopez-Terrada D, Lev D, Hornick JL, Hafeez Diwan A, Fletcher CD, Lazar AJ. Pleomorphic fibroma and dermal atypical lipomatous tumor: are they related? J Cutan Pathol. 2013 Apr; 40(4):379-84.
PMID:
23506010
.
Citations:
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Fong EL, Lamhamedi-Cherradi SE, Burdett E, Ramamoorthy V, Lazar AJ, Kasper FK, Farach-Carson MC, Vishwamitra D, Demicco EG, Menegaz BA, Amin HM, Mikos AG, Ludwig JA, Fong EL, Lamhamedi-Cherradi SE, Burdett E, Ramamoorthy V,
Lazar AJ
, Kasper FK, Farach-Carson MC, Vishwamitra D, Demicco EG, Menegaz BA,
Amin HM
, Mikos AG,
Ludwig JA
. Modeling Ewing sarcoma tumors in vitro with 3D scaffolds. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6500-5.
PMID:
23576741
; PMCID:
PMC3631678
.
Citations:
81
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Plantinga MJ, Pascarelli KM, Merkel AS, Lazar AJ, von Mehren M, Lev D, Broccoli D, Plantinga MJ, Pascarelli KM, Merkel AS,
Lazar AJ
, von Mehren M, Lev D, Broccoli D. Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles. Mol Cancer Res. 2013 Jun; 11(6):557-67.
PMID:
23505069
.
Citations:
10
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Kurek KC, Pansuriya TC, van Ruler MA, van den Akker B, Luks VL, Verbeke SL, Kozakewich HP, Sciot R, Lev D, Lazar AJ, Fletcher CD, Bovée JV, Kurek KC, Pansuriya TC, van Ruler MA, van den Akker B, Luks VL, Verbeke SL, Kozakewich HP, Sciot R, Lev D,
Lazar AJ
, Fletcher CD, Bovée JV, Bov?e JV. R132C IDH1 mutations are found in spindle cell hemangiomas and not in other vascular tumors or malformations. Am J Pathol. 2013 May; 182(5):1494-500.
PMID:
23485734
.
Citations:
8
Fields:
Pat
Pathology
Translation:
Humans
Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ,
Creighton CJ
, Bolshakov S, McKay RM, Lev D, Le LQ, Parada LF, Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J,
Lazar AJ
, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, Parada LF, McKay RM. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 2013 Feb 28; 152(5):1077-90.
PMID:
23434321
; PMCID:
PMC3594500
.
Citations:
81
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Hoffman A, Ghadimi MP, Demicco EG,
Creighton CJ
,
Torres K
, Colombo C, Peng T, Lusby K, Ingram D, Hornick JL,
Wang WL
, Ravi V, Lazar AJ, Lev D, Pollock RE, Hoffman A, Ghadimi MP, Demicco EG, Creighton CJ, Torres K, Colombo C, Peng T, Lusby K, Ingram D, Hornick JL, Wang WL,
Ravi V
,
Lazar AJ
, Lev D, Pollock RE. Localized and metastatic myxoid/round cell liposarcoma: clinical and molecular observations. Cancer. 2013 May 15; 119(10):1868-77.
PMID:
23401071
.
Citations:
43
Fields:
Neo
Neoplasms
Translation:
Humans
Lusby K, Savannah KB, Demicco EG, Zhang Y, Ghadimi MP, Young ED, Colombo C, Lam R, Dogan TE, Hornick JL,
Lazar AJ
, Hunt KK, Anderson ML,
Creighton CJ
, Lev D, Pollock RE, Lusby K, Savannah KB, Demicco EG, Zhang Y, Ghadimi MP, Young ED, Colombo C, Lam R, Dogan TE, Hornick JL, Lazar AJ,
Hunt KK
, Anderson ML, Creighton CJ, Lev D, Pollock RE. Uterine leiomyosarcoma management, outcome, and associated molecular biomarkers: a single institution's experience. Ann Surg Oncol. 2013 Jul; 20(7):2364-72.
PMID:
23334251
; PMCID:
PMC3913478
.
Citations:
32
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Wang WL, Katz D, Araujo DM, Ravi V, Ludwig JA, Trent JC,
Patel SR
,
Lin PP
, Guadagnolo A, Lòpez-Terrada D, Dei Tos AP, Lewis VO, Lev D, Pollock RE,
Zagars GK
, Benjamin RS,
Madewell JE
, Lazar AJ, Wang WL, Katz D,
Araujo DM
,
Ravi V
,
Ludwig JA
, Trent JC, Patel SR, Lin PP, Guadagnolo A, Lòpez-Terrada D, Dei Tos AP, Lewis VO, Lev D, Pollock RE, Zagars GK, Benjamin RS, Madewell JE,
Lazar AJ
, L?pez-Terrada D. Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy. Clin Sarcoma Res. 2012 Dec 29; 2(1):25.
PMID:
23272660
; PMCID:
PMC3599544
.
Citations:
5
Greaves WO, Verma S, Patel KP,
Davies MA
, Barkoh BA, Galbincea JM, Yao H,
Lazar AJ
, Aldape KD,
Medeiros LJ
,
Luthra R
, Greaves WO, Verma S,
Patel KP
, Davies MA, Barkoh BA, Galbincea JM, Yao H, Lazar AJ, Aldape KD, Medeiros LJ, Luthra R. Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma. J Mol Diagn. 2013 Mar; 15(2):220-6.
PMID:
23273605
; PMCID:
PMC5707183
.
Citations:
84
Fields:
Mol
Molecular Biology
Translation:
Humans
Cells
Wang S, Li J, Manapuram RK, Menodiado FM, Ingram DR, Twa MD,
Lazar AJ
, Lev DC, Pollock RE, Larin KV, Wang S, Li J, Manapuram RK, Menodiado FM, Ingram DR, Twa MD, Lazar AJ, Lev DC, Pollock RE,
Larin KV
. Noncontact measurement of elasticity for the detection of soft-tissue tumors using phase-sensitive optical coherence tomography combined with a focused air-puff system. Opt Lett. 2012 Dec 15; 37(24):5184-6.
PMID:
23258046
; PMCID:
PMC4589295
.
Citations:
38
Fields:
Oph
Ophthalmology
Translation:
Humans
Cells
Torres KE, Ravi V, Kin K, Yi M,
Guadagnolo BA
, May CD, Arun BK, Hunt KK, Lam R, Lahat G, Hoffman A,
Cormier JN
,
Feig BW
, Lazar AJ, Lev D, Pollock RE,
Torres KE
,
Ravi V
, Kin K, Yi M, Guadagnolo BA, May CD,
Arun BK
,
Hunt KK
, Lam R, Lahat G, Hoffman A, Cormier JN, Feig BW,
Lazar AJ
, Lev D, Pollock RE. Long-term outcomes in patients with radiation-associated angiosarcomas of the breast following surgery and radiotherapy for breast cancer. Ann Surg Oncol. 2013 Apr; 20(4):1267-74.
PMID:
23224828
; PMCID:
PMC5036516
.
Citations:
34
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Suchak R,
Wang WL
, Prieto VG, Ivan D, Lazar AJ, Brenn T, Calonje E, Suchak R, Wang WL,
Prieto VG
,
Ivan D
,
Lazar AJ
, Brenn T, Calonje E. Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations. Am J Surg Pathol. 2012 Dec; 36(12):1883-91.
PMID:
23026931
.
Citations:
18
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Doyle LA,
Wang WL
, Dal Cin P, Lopez-Terrada D, Mertens F, Lazar AJ, Fletcher CD, Hornick JL, Doyle LA, Wang WL, Dal Cin P,
Lopez-Terrada D
, Mertens F,
Lazar AJ
, Fletcher CD, Hornick JL. MUC4 is a sensitive and extremely useful marker for sclerosing epithelioid fibrosarcoma: association with FUS gene rearrangement. Am J Surg Pathol. 2012 Oct; 36(10):1444-51.
PMID:
22982887
.
Citations:
42
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Cells
Patel SP,
Lazar AJ
, Papadopoulos NE, Liu P, Infante JR, Glass MR, Vaughn CS, LoRusso PM, Cohen RB,
Davies MA
, Kim KB,
Patel SP
, Lazar AJ, Papadopoulos NE, Liu P, Infante JR, Glass MR, Vaughn CS, LoRusso PM, Cohen RB, Davies MA, Kim KB. Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma. Cancer. 2013 Feb 15; 119(4):799-805.
PMID:
22972589
.
Citations:
38
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ghadimi MP, Lopez G,
Torres KE
, Belousov R, Young ED, Liu J, Brewer KJ, Hoffman A, Lusby K, Lazar AJ, Pollock RE, Lev D, Ghadimi MP, Lopez G, Torres KE, Belousov R, Young ED, Liu J, Brewer KJ, Hoffman A, Lusby K,
Lazar AJ
, Pollock RE, Lev D. Targeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumors. Mol Cancer Ther. 2012 Aug; 11(8):1758-69.
PMID:
22848094
; PMCID:
PMC3416967
.
Citations:
29
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Yang J, Kantrow S, Sai J, Hawkins OE, Boothby M, Ayers GD, Young ED, Demicco EG, Lazar AJ, Lev D, Richmond A, Yang J, Kantrow S, Sai J, Hawkins OE, Boothby M, Ayers GD, Young ED, Demicco EG,
Lazar AJ
, Lev D, Richmond A. INK4a/ARF [corrected] inactivation with activation of the NF-?B/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma. Cancer Res. 2012 Sep 15; 72(18):4682-95.
PMID:
22836752
; PMCID:
PMC3459578
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Brewer Savannah KJ, Demicco EG, Lusby K, Ghadimi MP, Belousov R, Young E, Zhang Y, Huang KL, Lazar AJ, Hunt KK, Pollock RE, Creighton CJ, Anderson ML, Lev D, Brewer Savannah KJ, Demicco EG, Lusby K, Ghadimi MP, Belousov R, Young E, Zhang Y, Huang KL,
Lazar AJ
,
Hunt KK
, Pollock RE,
Creighton CJ
, Anderson ML, Lev D. Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma. Clin Cancer Res. 2012 Sep 01; 18(17):4633-45.
PMID:
22821997
; PMCID:
PMC3432751
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Kim J, Lazar AJ,
Davies MA
, Homsi J, Papadopoulos NE,
Hwu WJ
, Bedikian AY,
Woodman SE
, Patel SP,
Hwu P
, Kim KB, Kim J,
Lazar AJ
, Davies MA, Homsi J, Papadopoulos NE, Hwu WJ, Bedikian AY, Woodman SE,
Patel SP
, Hwu P, Kim KB. BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma. J Cutan Pathol. 2012 Sep; 39(9):821-5.
PMID:
22809251
; PMCID:
PMC3881367
.
Citations:
6
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
CT
Clinical Trials
Zimmerman MA, Rahman NT, Yang D, Lahat G, Lazar AJ, Pollock RE, Lev D, Liu K, Zimmerman MA, Rahman NT, Yang D, Lahat G,
Lazar AJ
, Pollock RE, Lev D, Liu K. Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance. Cancer Res. 2012 Sep 15; 72(18):4724-32.
PMID:
22805310
; PMCID:
PMC3564959
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Foo WC
, Liegl-Atzwanger B,
Lazar AJ
, Foo WC, Liegl-Atzwanger B, Lazar AJ. Pathology of gastrointestinal stromal tumors. Clin Med Insights Pathol. 2012; 5:23-33.
PMID:
22855636
; PMCID:
PMC3408870
.
Citations:
15
Wang WL
, Patel NR, Caragea M, Hogendoorn PC, López-Terrada D, Hornick JL, Lazar AJ, Wang WL, Patel NR, Caragea M, Hogendoorn PC, López-Terrada D, Hornick JL,
Lazar AJ
, L?pez-Terrada D. Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma. Mod Pathol. 2012 Oct; 25(10):1378-83.
PMID:
22766791
.
Citations:
27
Fields:
Pat
Pathology
Translation:
Humans
Animals
Cells
McKay KM, Doyle LA,
Lazar AJ
, Hornick JL, McKay KM, Doyle LA, Lazar AJ, Hornick JL. Expression of ERG, an Ets family transcription factor, distinguishes cutaneous angiosarcoma from histological mimics. Histopathology. 2012 Nov; 61(5):989-91.
PMID:
22716285
.
Citations:
8
Fields:
Pat
Pathology
Translation:
Humans
Alexander LJ, Paravar T,
Duvic M
,
Prieto V
,
Hymes SR
, Alexander LJ, Paravar T, Duvic M, Prieto V, Hymes SR. Annular plaques: An unusual manifestation of graft-versus-host disease. Dermatol Online J. 2012 Jun 15; 18(6):4.
PMID:
22747928
.
Citations:
1
Fields:
Der
Dermatology
Translation:
Humans
Tseng WW, Demicco EG, Lazar AJ, Lev DC, Pollock RE, Tseng WW, Demicco EG,
Lazar AJ
, Lev DC, Pollock RE. Lymphocyte composition and distribution in inflammatory, well-differentiated retroperitoneal liposarcoma: clues to a potential adaptive immune response and therapeutic implications. Am J Surg Pathol. 2012 Jun; 36(6):941-4.
PMID:
22446945
.
Citations:
12
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Cells
Demicco EG, Park MS, Araujo DM, Fox PS, Bassett RL, Pollock RE,
Lazar AJ
,
Wang WL
, Demicco EG, Park MS,
Araujo DM
, Fox PS, Bassett RL, Pollock RE, Lazar AJ, Wang WL. Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model. Mod Pathol. 2012 Sep; 25(9):1298-306.
PMID:
22575866
.
Citations:
114
Fields:
Pat
Pathology
Translation:
Humans
Demicco EG, Maki RG, Lev DC,
Lazar AJ
, Demicco EG, Maki RG, Lev DC, Lazar AJ. New therapeutic targets in soft tissue sarcoma. Adv Anat Pathol. 2012 May; 19(3):170-80.
PMID:
22498582
; PMCID:
PMC3353406
.
Citations:
20
Fields:
Ana
Anatomy
Pat
Pathology
Translation:
Humans
Colombo C,
Foo WC
, Whiting D, Young ED, Lusby K, Pollock RE, Lazar AJ, Lev D, Colombo C, Foo WC, Whiting D, Young ED, Lusby K, Pollock RE,
Lazar AJ
, Lev D. FAP-related desmoid tumors: a series of 44 patients evaluated in a cancer referral center. Histol Histopathol. 2012 05; 27(5):641-9.
PMID:
22419028
.
Citations:
12
Fields:
His
Histology
Pat
Pathology
Translation:
Humans
Al-Zaid T, Ditelberg JS, Prieto VG, Lev D,
Luthra R
, Davies MA, Diwan AH,
Wang WL
, Lazar AJ, Al-Zaid T, Ditelberg JS,
Prieto VG
, Lev D, Luthra R,
Davies MA
,
Diwan AH
, Wang WL,
Lazar AJ
. Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors. J Cutan Pathol. 2012 May; 39(5):493-9.
PMID:
22486434
.
Citations:
8
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Li Q, Li M, Wang YL, Fauzee NJ, Yang Y, Pan J, Yang L,
Lazar A
, Li Q, Li M, Wang YL, Fauzee NJ, Yang Y, Pan J, Yang L, Lazar A. RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway. Cell Physiol Biochem. 2012; 29(3-4):361-72.
PMID:
22508044
.
Citations:
11
Fields:
Bio
Biochemistry
Cel
Cell Biology
Pha
Pharmacology
Translation:
Humans
Animals
Cells
Shalin SC, Sakharpe A, Lyle S, Lev D, Calonje E, Lazar AJ, Shalin SC, Sakharpe A, Lyle S, Lev D, Calonje E,
Lazar AJ
. p53 staining correlates with tumor type and location in sebaceous neoplasms. Am J Dermatopathol. 2012 Apr; 34(2):129-35; quiz 136-8.
PMID:
22441365
; PMCID:
PMC3313553
.
Citations:
8
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Ghadimi MP, Young ED, Belousov R, Zhang Y, Lopez G, Lusby K, Kivlin C, Demicco EG, Creighton CJ,
Lazar AJ
, Pollock RE, Lev D, Ghadimi MP, Young ED, Belousov R, Zhang Y, Lopez G, Lusby K, Kivlin C, Demicco EG,
Creighton CJ
, Lazar AJ, Pollock RE, Lev D. Survivin is a viable target for the treatment of malignant peripheral nerve sheath tumors. Clin Cancer Res. 2012 May 01; 18(9):2545-57.
PMID:
22407831
; PMCID:
PMC3932367
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Wang WL
, Evans HL, Meis JM, Liegl-Atzwanger B, Bovee JV, Goldblum JR, Billings SD, Rubin BP, López-Terrada D,
Lazar AJ
, Wang WL, Evans HL,
Meis JM
, Liegl-Atzwanger B, Bovee JV, Goldblum JR, Billings SD, Rubin BP, López-Terrada D, Lazar AJ, L?pez-Terrada D. FUS rearrangements are rare in 'pure' sclerosing epithelioid fibrosarcoma. Mod Pathol. 2012 Jun; 25(6):846-53.
PMID:
22388756
.
Citations:
10
Fields:
Pat
Pathology
Translation:
Humans
Cells
Shvartsbeyn M, Lazar AJ, Lopez-Terrada D, Meehan SA, Shvartsbeyn M,
Lazar AJ
,
Lopez-Terrada D
, Meehan SA. Pseudocystic dermatofibrosarcoma protuberans: report of two cases and demonstration of COL1A1-PDGFB rearrangement. J Cutan Pathol. 2012 Mar; 39(3):356-60.
PMID:
22335595
.
Citations:
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Wang WL
, Nero C, Pappo A, Lev D,
Lazar AJ
, López-Terrada D, Wang WL, Nero C, Pappo A, Lev D, Lazar AJ, López-Terrada D, L?pez-Terrada D. CTNNB1 genotyping and APC screening in pediatric desmoid tumors: a proposed algorithm. Pediatr Dev Pathol. 2012 Sep-Oct; 15(5):361-7.
PMID:
22372443
.
Citations:
13
Fields:
Pat
Pathology
Ped
Pediatrics
Translation:
Humans
Zhang P, Bill K, Liu J, Young E, Peng T, Bolshakov S, Hoffman A, Song Y, Demicco EG, Terrada DL,
Creighton CJ
, Anderson ML, Lazar AJ, Calin GG, Pollock RE, Lev D, Zhang P, Bill K, Liu J, Young E, Peng T, Bolshakov S, Hoffman A, Song Y, Demicco EG, Terrada DL, Creighton CJ, Anderson ML,
Lazar AJ
,
Calin GG
, Pollock RE, Lev D. MiR-155 is a liposarcoma oncogene that targets casein kinase-1a and enhances ?-catenin signaling. Cancer Res. 2012 Apr 01; 72(7):1751-62.
PMID:
22350414
; PMCID:
PMC3319789
.
Citations:
54
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Edris B, Espinosa I, Mühlenberg T, Mikels A, Lee CH, Steigen SE, Zhu S, Montgomery KD, Lazar AJ, Lev D, Fletcher JA, Beck AH, West RB, Nusse R, van de Rijn M, Edris B, Espinosa I, Mühlenberg T, Mikels A, Lee CH, Steigen SE, Zhu S, Montgomery KD,
Lazar AJ
, Lev D, Fletcher JA, Beck AH, West RB, Nusse R, van de Rijn M, Espinosa I, M?hlenberg T. ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour. J Pathol. 2012 Jun; 227(2):223-33.
PMID:
22294416
; PMCID:
PMC3992120
.
Citations:
42
Fields:
Pat
Pathology
Translation:
Humans
Animals
Cells
Woodman SE
, Lazar AJ, Aldape KD, Davies MA, Woodman SE,
Lazar AJ
, Aldape KD,
Davies MA
. New strategies in melanoma: molecular testing in advanced disease. Clin Cancer Res. 2012 Mar 01; 18(5):1195-200.
PMID:
22275506
; PMCID:
PMC4109407
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Katz D, Boonsirikamchai P, Choi H, Lazar AJ, Wang WL, Xiao L, Park MS, Ravi V, Benjamin RS,
Araujo DM
, Katz D, Boonsirikamchai P, Choi H,
Lazar AJ
, Wang WL, Xiao L, Park MS,
Ravi V
, Benjamin RS, Araujo DM. Efficacy of first-line doxorubicin and ifosfamide in myxoid liposarcoma. Clin Sarcoma Res. 2012 Jan 24; 2(1):2.
PMID:
22587772
; PMCID:
PMC3351704
.
Citations:
22
Davies MA, Fox PS, Papadopoulos NE, Bedikian AY,
Hwu WJ
,
Lazar AJ
,
Prieto VG
, Culotta KS, Madden TL, Xu Q, Huang S, Deng W, Ng CS, Gupta S, Liu W, Dancey JE, Wright JJ, Bassett RL,
Hwu P
, Kim KB,
Davies MA
, Fox PS, Papadopoulos NE, Bedikian AY, Hwu WJ, Lazar AJ, Prieto VG, Culotta KS, Madden TL, Xu Q, Huang S, Deng W,
Ng CS
,
Gupta S
, Liu W, Dancey JE, Wright JJ, Bassett RL, Hwu P, Kim KB. Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma. Clin Cancer Res. 2012 Feb 15; 18(4):1120-8.
PMID:
22223528
; PMCID:
PMC3906678
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Chen LL, Chen X, Choi H, Sang H, Chen LC, Zhang H, Gouw L, Andtbacka RH, Chan BK, Rodesch CK, Jimenez A, Cano P, Jones KA, Oyedeji CO, Martins T, Hill HR, Schumacher J, Willmore C, Scaife CL, Ward JH, Morton K, Randall RL,
Lazar AJ
,
Patel S
, Trent JC, Frazier ML,
Lin P
, Jensen P, Benjamin RS, Chen LL, Chen X, Choi H, Sang H, Chen LC, Zhang H, Gouw L, Andtbacka RH, Chan BK, Rodesch CK, Jimenez A, Cano P, Jones KA, Oyedeji CO, Martins T, Hill HR, Schumacher J, Willmore C, Scaife CL, Ward JH, Morton K, Randall RL, Lazar AJ, Patel S, Trent JC, Frazier ML, Lin P, Jensen P, Benjamin RS. Exploiting antitumor immunity to overcome relapse and improve remission duration. Cancer Immunol Immunother. 2012 Jul; 61(7):1113-24.
PMID:
22198309
; PMCID:
PMC3378844
.
Citations:
20
Fields:
All
Allergy and Immunology
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
CT
Clinical Trials
Jakob JA, Bassett RL, Ng CS, Curry JL, Joseph RW, Alvarado GC, Rohlfs ML, Richard J,
Gershenwald JE
, Kim KB,
Lazar AJ
,
Hwu P
,
Davies MA
, Jakob JA, Bassett RL,
Ng CS
,
Curry JL
, Joseph RW, Alvarado GC, Rohlfs ML, Richard J, Gershenwald JE, Kim KB, Lazar AJ, Hwu P, Davies MA. NRAS mutation status is an independent prognostic factor in metastatic melanoma. Cancer. 2012 Aug 15; 118(16):4014-23.
PMID:
22180178
; PMCID:
PMC3310961
.
Citations:
257
Fields:
Neo
Neoplasms
Translation:
Humans
Trufant J, Kurz W, Frankel A, Muthusamy V, McKinnon W, Greenblatt M,
Lazar A
, Cook D, Bosenberg M, Trufant J, Kurz W, Frankel A, Muthusamy V, McKinnon W, Greenblatt M, Lazar A, Cook D, Bosenberg M. Familial multiple pilomatrixomas as a presentation of attenuated adenomatosis polyposis coli. J Cutan Pathol. 2012 Apr; 39(4):440-3.
PMID:
22150579
.
Citations:
6
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Dumont SN,
Lazar AJ
, Bridge JA, Benjamin RS, Trent JC, Dumont SN, Lazar AJ, Bridge JA, Benjamin RS, Trent JC. PAX3/7-FOXO1 fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization. J Cancer Res Clin Oncol. 2012 Feb; 138(2):213-20.
PMID:
22089931
; PMCID:
PMC3932368
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Berri RN,
Baumann DP
,
Madewell JE
,
Lazar A
, Pollock RE, Berri RN, Baumann DP, Madewell JE, Lazar A, Pollock RE. Desmoid tumor: current multidisciplinary approaches. Ann Plast Surg. 2011 Nov; 67(5):551-64.
PMID:
21587055
.
Citations:
14
Fields:
Gen
General Surgery
Translation:
Humans
Demicco EG,
Torres KE
, Ghadimi MP, Colombo C, Bolshakov S, Hoffman A, Peng T, Bovée JV, Wang WL, Lev D, Lazar AJ, Demicco EG, Torres KE, Ghadimi MP, Colombo C, Bolshakov S, Hoffman A, Peng T, Bovée JV,
Wang WL
, Lev D,
Lazar AJ
, Bov?e JV. Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma. Mod Pathol. 2012 Feb; 25(2):212-21.
PMID:
22020193
; PMCID:
PMC3266971
.
Citations:
36
Fields:
Pat
Pathology
Translation:
Humans
Cells
Dumont AG, Rink L, Godwin AK, Miettinen M, Joensuu H, Strosberg JR, Gronchi A, Corless CL, Goldstein D, Rubin BP, Maki RG,
Lazar AJ
, Lev D, Trent JC, von Mehren M, Dumont AG, Rink L, Godwin AK, Miettinen M, Joensuu H, Strosberg JR, Gronchi A, Corless CL, Goldstein D, Rubin BP, Maki RG, Lazar AJ, Lev D, Trent JC, von Mehren M. A nonrandom association of gastrointestinal stromal tumor (GIST) and desmoid tumor (deep fibromatosis): case series of 28 patients. Ann Oncol. 2012 May; 23(5):1335-1340.
PMID:
21994214
; PMCID:
PMC3493136
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Wang WL
, Bones-Valentin RA,
Prieto VG
, Pollock RE, Lev DC,
Lazar AJ
, Wang WL, Bones-Valentin RA, Prieto VG, Pollock RE, Lev DC, Lazar AJ. Sarcoma metastases to the skin: a clinicopathologic study of 65 patients. Cancer. 2012 Jun 01; 118(11):2900-4.
PMID:
21989966
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Demicco EG,
Lazar AJ
, Demicco EG, Lazar AJ. Clinicopathologic considerations: how can we fine tune our approach to sarcoma? Semin Oncol. 2011 Oct; 38 Suppl 3:S3-18.
PMID:
22055969
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Lahat G, Zhang P, Zhu QS,
Torres K
, Ghadimi M, Smith KD, Wang WL, Lazar AJ, Lev D, Lahat G, Zhang P, Zhu QS, Torres K, Ghadimi M, Smith KD,
Wang WL
,
Lazar AJ
, Lev D. The expression of c-Met pathway components in unclassified pleomorphic sarcoma/malignant fibrous histiocytoma (UPS/MFH): a tissue microarray study. Histopathology. 2011 Sep; 59(3):556-61.
PMID:
22034893
.
Citations:
14
Fields:
Pat
Pathology
Translation:
Humans
Tanas MR, Sboner A, Oliveira AM, Erickson-Johnson MR, Hespelt J, Hanwright PJ, Flanagan J, Luo Y, Fenwick K, Natrajan R, Mitsopoulos C, Zvelebil M, Hoch BL, Weiss SW, Debiec-Rychter M, Sciot R, West RB,
Lazar AJ
, Ashworth A, Reis-Filho JS, Lord CJ, Gerstein MB, Rubin MA, Rubin BP, Tanas MR, Sboner A, Oliveira AM, Erickson-Johnson MR, Hespelt J, Hanwright PJ, Flanagan J, Luo Y, Fenwick K, Natrajan R, Mitsopoulos C, Zvelebil M, Hoch BL, Weiss SW, Debiec-Rychter M, Sciot R, West RB, Lazar AJ, Ashworth A, Reis-Filho JS, Lord CJ, Gerstein MB, Rubin MA, Rubin BP. Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma. Sci Transl Med. 2011 Aug 31; 3(98):98ra82.
PMID:
21885404
.
Citations:
117
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Colombo C,
Creighton CJ
, Ghadimi MP, Bolshakov S, Warneke CL, Zhang Y, Lusby K, Zhu S, Lazar AJ, West RB, van de Rijn M, Lev D, Colombo C, Creighton CJ, Ghadimi MP, Bolshakov S, Warneke CL, Zhang Y, Lusby K, Zhu S,
Lazar AJ
, West RB, van de Rijn M, Lev D. Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target. J Pathol. 2011 Dec; 225(4):574-82.
PMID:
21826666
.
Citations:
10
Fields:
Pat
Pathology
Translation:
Humans
Cells
Xie X, Ghadimi MP, Young ED, Belousov R, Zhu QS, Liu J, Lopez G, Colombo C, Peng T, Reynoso D, Hornick JL, Lazar AJ, Lev D, Xie X, Ghadimi MP, Young ED, Belousov R, Zhu QS, Liu J, Lopez G, Colombo C, Peng T, Reynoso D, Hornick JL,
Lazar AJ
, Lev D. Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma. Clin Cancer Res. 2011 Sep 15; 17(18):5901-12.
PMID:
21821699
; PMCID:
PMC3176924
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Colombo C, Bolshakov S, Hajibashi S,
Lopez-Terrada L
,
Wang WL
,
Rao P
, Benjamin RS,
Lazar AJ
, Lev D, Colombo C, Bolshakov S, Hajibashi S, Lopez-Terrada L, Wang WL, Rao P, Benjamin RS, Lazar AJ, Lev D. 'Difficult to diagnose' desmoid tumours: a potential role for CTNNB1 mutational analysis. Histopathology. 2011 Aug; 59(2):336-40.
PMID:
21884214
.
Citations:
10
Fields:
Pat
Pathology
Translation:
Humans
Wang X, Asmann YW, Erickson-Johnson MR, Oliveira JL, Zhang H, Moura RD,
Lazar AJ
, Lev D, Bill K, Lloyd RV, Yaszemski MJ, Maran A, Oliveira AM, Wang X, Asmann YW, Erickson-Johnson MR, Oliveira JL, Zhang H, Moura RD, Lazar AJ, Lev D, Bill K, Lloyd RV, Yaszemski MJ, Maran A, Oliveira AM. High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma. Genes Chromosomes Cancer. 2011 Nov; 50(11):849-58.
PMID:
21793095
.
Citations:
24
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Torres KE
, Liu J, Young E, Huang KL, Ghadimi M, Lusby K,
Lazar AJ
, Lev D, Torres KE, Liu J, Young E, Huang KL, Ghadimi M, Lusby K, Lazar AJ, Lev D. Expression of 'drugable' tyrosine kinase receptors in malignant peripheral nerve sheath tumour: potential molecular therapeutic targets for a chemoresistant cancer. Histopathology. 2011 Jul; 59(1):156-9.
PMID:
21771036
; PMCID:
PMC4532392
.
Citations:
6
Fields:
Pat
Pathology
Translation:
Humans
Swaby MG, Evans HL, Fletcher CD,
Prieto VG
, Patel KU, Lev DC, Lòpez-Terrada D,
Lazar AJ
, Wang WL, Swaby MG, Evans HL, Fletcher CD, Prieto VG, Patel KU, Lev DC, Lòpez-Terrada D, Lazar AJ,
Wang WL
, L?pez-Terrada D. Dermatofibrosarcoma protuberans with unusual sarcomatous transformation: a series of 4 cases with molecular confirmation. Am J Dermatopathol. 2011 Jun; 33(4):354-60.
PMID:
21478726
.
Citations:
2
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Diwan AH, Lazar AJ,
Diwan AH
,
Lazar AJ
. Nevoid melanoma. Clin Lab Med. 2011 Jun; 31(2):243-53.
PMID:
21549238
.
Citations:
4
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Ghadimi MP, Al-Zaid T, Madewell J, Peng T, Colombo C, Hoffman A,
Creighton CJ
, Zhang Y, Zhang A,
Lazar AJ
, Pollock RE, Lev D, Ghadimi MP, Al-Zaid T,
Madewell J
, Peng T, Colombo C, Hoffman A, Creighton CJ, Zhang Y, Zhang A, Lazar AJ, Pollock RE, Lev D. Diagnosis, management, and outcome of patients with dedifferentiated liposarcoma systemic metastasis. Ann Surg Oncol. 2011 Dec; 18(13):3762-70.
PMID:
21614627
.
Citations:
23
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Ghadimi MP, Liu P, Peng T, Bolshakov S, Young ED,
Torres KE
, Colombo C, Hoffman A, Broccoli D, Hornick JL,
Lazar AJ
, Pisters P, Pollock RE, Lev D, Ghadimi MP, Liu P, Peng T, Bolshakov S, Young ED, Torres KE, Colombo C, Hoffman A, Broccoli D, Hornick JL, Lazar AJ, Pisters P, Pollock RE, Lev D. Pleomorphic liposarcoma: clinical observations and molecular variables. Cancer. 2011 Dec 01; 117(23):5359-69.
PMID:
21598240
; PMCID:
PMC3161152
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Torres KE, Zhu QS, Bill K, Lopez G, Ghadimi MP, Xie X, Young ED, Liu J, Nguyen T, Bolshakov S, Belousov R, Wang S, Lahat G, Liu J, Hernandez B,
Lazar AJ
, Lev D,
Torres KE
, Zhu QS, Bill K, Lopez G, Ghadimi MP, Xie X, Young ED, Liu J, Nguyen T, Bolshakov S, Belousov R, Wang S, Lahat G, Liu J, Hernandez B, Lazar AJ, Lev D. Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors. Clin Cancer Res. 2011 Jun 15; 17(12):3943-55.
PMID:
21540237
; PMCID:
PMC3117912
.
Citations:
45
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Park MS, Patel SR, Ludwig JA, Trent JC, Conrad CA, Lazar AJ,
Wang WL
, Boonsirikamchai P, Choi H, Wang X, Benjamin RS, Araujo DM, Park MS,
Patel SR
,
Ludwig JA
, Trent JC, Conrad CA,
Lazar AJ
, Wang WL, Boonsirikamchai P, Choi H, Wang X, Benjamin RS,
Araujo DM
. Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor. Cancer. 2011 Nov 01; 117(21):4939-47.
PMID:
21480200
; PMCID:
PMC3135685
.
Citations:
72
Fields:
Neo
Neoplasms
Translation:
Humans
Huh WW, Yuen C, Munsell M,
Hayes-Jordan A
, Lazar AJ,
Patel S
,
Wang WL
, Barahmani N,
Okcu MF
, Hicks J, Debelenko L, Spunt SL,
Huh WW
, Yuen C, Munsell M, Hayes-Jordan A,
Lazar AJ
, Patel S, Wang WL, Barahmani N, Okcu MF, Hicks J, Debelenko L, Spunt SL. Liposarcoma in children and young adults: a multi-institutional experience. Pediatr Blood Cancer. 2011 Dec 15; 57(7):1142-6.
PMID:
21394894
; PMCID:
PMC3134599
.
Citations:
17
Fields:
Hem
Hematology
Neo
Neoplasms
Ped
Pediatrics
Translation:
Humans
Hsu A,
Esmaeli B
, Hayek B, Hossain MG, Shinder R,
Lazar AJ
, McCarty JH, Hsu A, Esmaeli B, Hayek B, Hossain MG, Shinder R, Lazar AJ,
McCarty JH
. Analysis of av integrin protein expression in human eyelid and periorbital squamous cell carcinomas. J Cutan Pathol. 2011 Jul; 38(7):570-5.
PMID:
21375561
.
Citations:
2
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Sakharpe A, Lahat G, Gulamhusein T, Liu P, Bolshakov S, Nguyen T, Zhang P, Belousov R, Young E, Xie X,
Rao P
, Hornick JL, Lazar AJ, Pollock RE, Lev D, Sakharpe A, Lahat G, Gulamhusein T, Liu P, Bolshakov S, Nguyen T, Zhang P, Belousov R, Young E, Xie X, Rao P, Hornick JL,
Lazar AJ
, Pollock RE, Lev D. Epithelioid sarcoma and unclassified sarcoma with epithelioid features: clinicopathological variables, molecular markers, and a new experimental model. Oncologist. 2011; 16(4):512-22.
PMID:
21357725
; PMCID:
PMC3228127
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Dayrit JF,
Wang WL
, Goh SG, Ramdial PK, Lazar AJ, Calonje E, Dayrit JF, Wang WL, Goh SG, Ramdial PK,
Lazar AJ
, Calonje E. T-cell-rich angiomatoid polypoid pseudolymphoma of the skin: a clinicopathologic study of 17 cases and a proposed nomenclature. J Cutan Pathol. 2011 Jun; 38(6):475-82.
PMID:
21352259
.
Citations:
2
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Carbajal EF, Baranov SA, Manne VG, Young ED, Lazar AJ, Lev DC, Pollock RE,
Larin KV
, Carbajal EF, Baranov SA, Manne VG, Young ED,
Lazar AJ
, Lev DC, Pollock RE, Larin KV. Revealing retroperitoneal liposarcoma morphology using optical coherence tomography. J Biomed Opt. 2011 Feb; 16(2):020502.
PMID:
21361658
.
Citations:
6
Fields:
Bio
Biomedical Engineering
Oph
Ophthalmology
Translation:
Humans
Mariño-Enríquez A,
Wang WL
,
Roy A
,
Lopez-Terrada D
, Lazar AJ, Fletcher CD, Coffin CM, Hornick JL, Mariño-Enríquez A, Wang WL, Roy A, Lopez-Terrada D,
Lazar AJ
, Fletcher CD, Coffin CM, Hornick JL, Mari?o-Enr?quez A. Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. Am J Surg Pathol. 2011 Jan; 35(1):135-44.
PMID:
21164297
.
Citations:
75
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Cells
Wang WL
, Conley A, Reynoso D, Nolden L,
Lazar AJ
, George S, Trent JC, Wang WL,
Conley A
, Reynoso D, Nolden L, Lazar AJ, George S, Trent JC. Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor. Cancer Chemother Pharmacol. 2011 Jan; 67 Suppl 1:S15-24.
PMID:
21181476
.
Citations:
23
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Hoffman A,
Lazar AJ
, Pollock RE, Lev D, Hoffman A, Lazar AJ, Pollock RE, Lev D. New frontiers in the treatment of liposarcoma, a therapeutically resistant malignant cohort. Drug Resist Updat. 2011 Feb; 14(1):52-66.
PMID:
21169051
.
Citations:
23
Fields:
Ant
Anti-Infective Agents
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Hu Q, Gao F, Tian W, Ruteshouser EC, Wang Y, Lazar A, Stewart J, Strong LC, Behringer RR, Huff V,
Hu Q
, Gao F, Tian W, Ruteshouser EC, Wang Y,
Lazar A
,
Stewart J
,
Strong LC
,
Behringer RR
,
Huff V
. Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation. J Clin Invest. 2011 Jan; 121(1):174-83.
PMID:
21123950
; PMCID:
PMC3007149
.
Citations:
57
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Lopez G, Torres K, Liu J, Hernandez B, Young E, Belousov R, Bolshakov S, Lazar AJ, Slopis JM, McCutcheon IE, McConkey D, Lev D, Lopez G,
Torres K
, Liu J, Hernandez B, Young E, Belousov R, Bolshakov S,
Lazar AJ
,
Slopis JM
,
McCutcheon IE
, McConkey D, Lev D. Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors. Cancer Res. 2011 Jan 01; 71(1):185-96.
PMID:
21084276
; PMCID:
PMC3064267
.
Citations:
49
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Peng T, Zhang P, Liu J, Nguyen T, Bolshakov S, Belousov R, Young ED, Wang X, Brewer K, López-Terrada DH, Oliveira AM,
Lazar AJ
, Lev D, Peng T, Zhang P, Liu J, Nguyen T, Bolshakov S, Belousov R, Young ED, Wang X, Brewer K, López-Terrada DH, Oliveira AM, Lazar AJ, Lev D, L?pez-Terrada DH. An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors. Lab Invest. 2011 Mar; 91(3):392-403.
PMID:
21060307
; PMCID:
PMC3058694
.
Citations:
44
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Animals
Cells
Zhu QS, Rosenblatt K, Huang KL, Lahat G, Brobey R, Bolshakov S, Nguyen T, Ding Z, Belousov R, Bill K, Luo X,
Lazar A
, Dicker A,
Mills GB
, Hung MC, Lev D, Zhu QS, Rosenblatt K, Huang KL, Lahat G, Brobey R, Bolshakov S, Nguyen T,
Ding Z
, Belousov R, Bill K, Luo X, Lazar A, Dicker A, Mills GB,
Hung MC
, Lev D. Vimentin is a novel AKT1 target mediating motility and invasion. Oncogene. 2011 Jan 27; 30(4):457-70.
PMID:
20856200
; PMCID:
PMC3010301
.
Citations:
104
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ylipää A,
Hunt KK
, Yang J, Lazar AJ, Torres KE, Lev DC, Nykter M, Pollock RE, Trent J, Zhang W, Ylipää A, Hunt KK, Yang J,
Lazar AJ
,
Torres KE
, Lev DC, Nykter M, Pollock RE, Trent J, Zhang W, Ylip?? A. Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors. Cancer. 2011 Jan 15; 117(2):380-9.
PMID:
20818650
; PMCID:
PMC3008331
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Gupta A, Roy S,
Lazar AJ
, Wang WL, McAuliffe JC, Reynoso D, McMahon J, Taguchi T, Floris G, Debiec-Rychter M, Schoffski P, Trent JA, Debnath J, Rubin BP, Gupta A, Roy S, Lazar AJ,
Wang WL
, McAuliffe JC, Reynoso D, McMahon J, Taguchi T, Floris G, Debiec-Rychter M, Schoffski P, Trent JA, Debnath J, Rubin BP. Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST). Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14333-8.
PMID:
20660757
; PMCID:
PMC2922542
.
Citations:
100
Fields:
Sci
Science
Translation:
Humans
Yang J, Eddy JA, Pan Y, Hategan A, Tabus I, Wang Y, Cogdell D, Price ND, Pollock RE, Lazar AJ,
Hunt KK
, Trent JC, Zhang W, Yang J, Eddy JA, Pan Y, Hategan A, Tabus I, Wang Y, Cogdell D, Price ND, Pollock RE,
Lazar AJ
, Hunt KK, Trent JC, Zhang W. Integrated proteomics and genomics analysis reveals a novel mesenchymal to epithelial reverting transition in leiomyosarcoma through regulation of slug. Mol Cell Proteomics. 2010 Nov; 9(11):2405-13.
PMID:
20651304
; PMCID:
PMC2984227
.
Citations:
33
Fields:
Bio
Biochemistry
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Brown JG, Folpe AL,
Rao P
,
Lazar AJ
, Paner GP, Gupta R, Parakh R, Cheville JC, Amin MB, Brown JG, Folpe AL, Rao P, Lazar AJ, Paner GP, Gupta R, Parakh R, Cheville JC, Amin MB. Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases. Am J Surg Pathol. 2010 Jul; 34(7):942-9.
PMID:
20534992
.
Citations:
29
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Powers MP,
Wang WL
, Hernandez VS, Patel KS, Lev DC,
Lazar AJ
, López-Terrada DH, Powers MP, Wang WL, Hernandez VS, Patel KS, Lev DC, Lazar AJ, López-Terrada DH, L?pez-Terrada DH. Detection of myxoid liposarcoma-associated FUS-DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay. Mod Pathol. 2010 Oct; 23(10):1307-15.
PMID:
20581806
.
Citations:
22
Fields:
Pat
Pathology
Translation:
Humans
Lahat G, Dhuka AR, Hallevi H, Xiao L, Zou C, Smith KD, Phung TL, Pollock RE, Benjamin R, Hunt KK,
Lazar AJ
, Lev D, Lahat G, Dhuka AR, Hallevi H, Xiao L, Zou C, Smith KD, Phung TL, Pollock RE, Benjamin R,
Hunt KK
, Lazar AJ, Lev D. Angiosarcoma: clinical and molecular insights. Ann Surg. 2010 Jun; 251(6):1098-106.
PMID:
20485141
.
Citations:
73
Fields:
Gen
General Surgery
Translation:
Humans
Weaver J,
Rao P
, Goldblum JR, Joyce MJ, Turner SL, Lazar AJ, López-Terada D, Tubbs RR, Rubin BP, Weaver J, Rao P, Goldblum JR, Joyce MJ, Turner SL,
Lazar AJ
, López-Terada D, Tubbs RR, Rubin BP, L?pez-Terada D. Can MDM2 analytical tests performed on core needle biopsy be relied upon to diagnose well-differentiated liposarcoma? Mod Pathol. 2010 Oct; 23(10):1301-6.
PMID:
20495536
.
Citations:
17
Fields:
Pat
Pathology
Translation:
Humans
Wang S, Ren W, Liu J, Lahat G, Torres K, Lopez G,
Lazar AJ
,
Hayes-Jordan A
, Liu K,
Bankson J
,
Hazle JD
, Lev D, Wang S, Ren W, Liu J, Lahat G,
Torres K
, Lopez G, Lazar AJ, Hayes-Jordan A, Liu K, Bankson J, Hazle JD, Lev D. TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivo. Clin Cancer Res. 2010 May 01; 16(9):2591-604.
PMID:
20406839
; PMCID:
PMC2967255
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Lahat G, Zhu QS, Huang KL, Wang S, Bolshakov S, Liu J, Torres K, Langley RR,
Lazar AJ
,
Hung MC
, Lev D, Lahat G, Zhu QS, Huang KL, Wang S, Bolshakov S, Liu J,
Torres K
, Langley RR, Lazar AJ, Hung MC, Lev D. Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies. PLoS One. 2010 Apr 16; 5(4):e10105.
PMID:
20419128
; PMCID:
PMC2855704
.
Citations:
99
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Wang WL
, Patel KU, Coleman NM, Smith-Zagone MJ,
Ivan D
, Reed JA, López-Terrada D, Lazar AJ,
Prieto VG
, Wang WL, Patel KU, Coleman NM, Smith-Zagone MJ, Ivan D, Reed JA, López-Terrada D,
Lazar AJ
, Prieto VG, L?pez-Terrada D. COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin. Am J Dermatopathol. 2010 Apr; 32(2):149-53.
PMID:
19940748
.
Citations:
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Cells
Rubin BP, Cooper K, Fletcher CD, Folpe AL, Gannon FH, Hunt JL, Lazar AJ, Montag AG, Peabody TD, Pollock RE, Reith JD, Qualman SJ, Rosenberg AE, Weiss SW, Krausz T, Rubin BP, Cooper K, Fletcher CD, Folpe AL,
Gannon FH
, Hunt JL,
Lazar AJ
, Montag AG, Peabody TD, Pollock RE, Reith JD, Qualman SJ, Rosenberg AE, Weiss SW, Krausz T, Members of the Cancer Committee, College of American Pathologists. Protocol for the examination of specimens from patients with tumors of soft tissue. Arch Pathol Lab Med. 2010 Apr; 134(4):e31-9.
PMID:
20367297
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
Reynoso D,
Subbiah V
, Trent JC,
Guadagnolo BA
,
Lazar AJ
, Benjamin R, Pollock RE, Ludwig JA, Reynoso D, Subbiah V, Trent JC, Guadagnolo BA, Lazar AJ, Benjamin R, Pollock RE,
Ludwig JA
. Neoadjuvant treatment of soft-tissue sarcoma: a multimodality approach. J Surg Oncol. 2010 Mar 15; 101(4):327-33.
PMID:
20187067
.
Citations:
9
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Rutkowski P, Van Glabbeke M, Rankin CJ, Ruka W, Rubin BP, Debiec-Rychter M,
Lazar A
, Gelderblom H, Sciot R,
Lopez-Terrada D
, Hohenberger P, van Oosterom AT, Schuetze SM, Rutkowski P, Van Glabbeke M, Rankin CJ, Ruka W, Rubin BP, Debiec-Rychter M, Lazar A, Gelderblom H, Sciot R, Lopez-Terrada D, Hohenberger P, van Oosterom AT, Schuetze SM, European Organisation for Research and Treatment of Cancer Soft Tissue/Bone Sarcoma Group, Southwest Oncology Group. Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials. J Clin Oncol. 2010 Apr 01; 28(10):1772-9.
PMID:
20194851
; PMCID:
PMC3040044
.
Citations:
87
Fields:
Neo
Neoplasms
Translation:
Humans
Hantschke M, Mentzel T, Rütten A, Palmedo G, Calonje E, Lazar AJ, Kutzner H, Hantschke M, Mentzel T, Rütten A, Palmedo G, Calonje E,
Lazar AJ
, Kutzner H, R?tten A. Cutaneous clear cell sarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 12 cases emphasizing its distinction from dermal melanoma. Am J Surg Pathol. 2010 Feb; 34(2):216-22.
PMID:
20087159
; PMCID:
PMC5798433
.
Citations:
22
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Cells
Rubin BP, Blanke CD, Demetri GD, Dematteo RP, Fletcher CD, Goldblum JR, Lasota J, Lazar A, Maki RG, Miettinen M, Noffsinger A, Washington MK, Krausz T, Rubin BP, Blanke CD, Demetri GD, Dematteo RP, Fletcher CD, Goldblum JR, Lasota J,
Lazar A
, Maki RG, Miettinen M, Noffsinger A, Washington MK, Krausz T, Cancer Committee, College of American Pathologists. Protocol for the examination of specimens from patients with gastrointestinal stromal tumor. Arch Pathol Lab Med. 2010 Feb; 134(2):165-70.
PMID:
20121601
.
Citations:
21
Fields:
Pat
Pathology
Translation:
Humans
Ostler DA, Prieto VG, Reed JA, Deavers MT, Lazar AJ,
Ivan D
, Ostler DA,
Prieto VG
, Reed JA, Deavers MT,
Lazar AJ
, Ivan D. Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases. Mod Pathol. 2010 Apr; 23(4):567-73.
PMID:
20118912
.
Citations:
26
Fields:
Pat
Pathology
Translation:
Humans
Powers M, Zhang W,
Lopez-Terrada D
,
Czerniak BA
, Lazar AJ, Powers M, Zhang W, Lopez-Terrada D, Czerniak BA,
Lazar AJ
. The molecular pathology of sarcomas. Cancer Biomark. 2010; 9(1-6):475-91.
PMID:
22112491
.
Citations:
10
Fields:
Bio
Biochemistry
Neo
Neoplasms
Translation:
Humans
Animals
Shalin SC, Lyle S, Calonje E, Lazar AJ, Shalin SC, Lyle S, Calonje E,
Lazar AJ
. Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications. Histopathology. 2010 Jan; 56(1):133-47.
PMID:
20055911
; PMCID:
PMC2805836
.
Citations:
31
Fields:
Pat
Pathology
Translation:
Humans
Davies MA, Stemke-Hale K, Lin E, Tellez C, Deng W, Gopal YN, Woodman SE, Calderone TC, Ju Z,
Lazar AJ
, Prieto VG, Aldape K,
Mills GB
,
Gershenwald JE
, Davies MA, Stemke-Hale K, Lin E, Tellez C, Deng W, Gopal YN,
Woodman SE
, Calderone TC, Ju Z, Lazar AJ,
Prieto VG
, Aldape K, Mills GB, Gershenwald JE. Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma. Clin Cancer Res. 2009 Dec 15; 15(24):7538-7546.
PMID:
19996208
; PMCID:
PMC2805170
.
Citations:
113
Fields:
Neo
Neoplasms
Lazar AJ
, Lahat G, Myers SE, Smith KD, Zou C, Wang WL,
Lopez-Terrada D
, Lev D, Lazar AJ, Lahat G, Myers SE, Smith KD, Zou C,
Wang WL
, Lopez-Terrada D, Lev D. Validation of potential therapeutic targets in alveolar soft part sarcoma: an immunohistochemical study utilizing tissue microarray. Histopathology. 2009 Dec; 55(6):750-5.
PMID:
20002771
.
Citations:
10
Fields:
Pat
Pathology
Translation:
Humans
Mito JK, Riedel RF, Dodd L, Lahat G,
Lazar AJ
, Dodd RD, Stangenberg L, Eward WC, Hornicek FJ, Yoon SS, Brigman BE, Jacks T, Lev D, Mukherjee S, Kirsch DG, Mito JK, Riedel RF, Dodd L, Lahat G, Lazar AJ, Dodd RD, Stangenberg L, Eward WC, Hornicek FJ, Yoon SS, Brigman BE, Jacks T, Lev D, Mukherjee S, Kirsch DG. Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. PLoS One. 2009 Nov 30; 4(11):e8075.
PMID:
19956606
; PMCID:
PMC2779485
.
Citations:
47
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Lahat G, Tuvin D, Wei C, Wang WL, Pollock RE, Anaya DA, Bekele BN, Corely L, Lazar AJ, Pisters PW, Lev D, Lahat G, Tuvin D, Wei C,
Wang WL
, Pollock RE, Anaya DA, Bekele BN, Corely L,
Lazar AJ
, Pisters PW, Lev D. Molecular prognosticators of complex karyotype soft tissue sarcoma outcome: a tissue microarray-based study. Ann Oncol. 2010 May; 21(5):1112-20.
PMID:
19875755
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Diwan AH, Lazar AJ,
Diwan AH
,
Lazar AJ
. Nevoid Melanoma. Surg Pathol Clin. 2009 Sep; 2(3):521-33.
PMID:
26838537
.
Citations:
Fields:
Gen
General Surgery
Katz D,
Lazar A
, Lev D, Katz D, Lazar A, Lev D. Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways. Expert Rev Mol Med. 2009 Oct 19; 11:e30.
PMID:
19835664
.
Citations:
42
Fields:
Mol
Molecular Biology
Translation:
Humans
Cells
Torres-Cabala CA,
Wang WL
, Trent J, Yang D, Chen S, Galbincea J, Kim KB, Woodman S, Davies M, Plaza JA, Nash JW,
Prieto VG
,
Lazar AJ
,
Ivan D
, Torres-Cabala CA, Wang WL, Trent J, Yang D, Chen S, Galbincea J, Kim KB,
Woodman S
, Davies M, Plaza JA, Nash JW, Prieto VG, Lazar AJ, Ivan D. Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type. Mod Pathol. 2009 Nov; 22(11):1446-56.
PMID:
19718013
; PMCID:
PMC4120323
.
Citations:
48
Fields:
Pat
Pathology
Translation:
Humans
Woodman SE, Trent JC, Stemke-Hale K, Lazar AJ, Pricl S, Pavan GM, Fermeglia M, Gopal YN, Yang D, Podoloff DA,
Ivan D
, Kim KB, Papadopoulos N, Hwu P,
Mills GB
, Davies MA,
Woodman SE
, Trent JC, Stemke-Hale K,
Lazar AJ
, Pricl S, Pavan GM, Fermeglia M, Gopal YN, Yang D, Podoloff DA, Ivan D, Kim KB, Papadopoulos N,
Hwu P
, Mills GB,
Davies MA
. Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates. Mol Cancer Ther. 2009 Aug; 8(8):2079-85.
PMID:
19671763
; PMCID:
PMC3346953
.
Citations:
68
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
Ivan D
,
Prieto VG
,
Esmaeli B
, Wistuba II, Tang X,
Lazar AJ
, Ivan D, Prieto VG, Esmaeli B,
Wistuba II
, Tang X, Lazar AJ. Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma. J Cutan Pathol. 2010 Feb; 37(2):231-6.
PMID:
19614729
.
Citations:
5
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Blazer DG,
Lazar AJ
, Xing Y, Askew RL,
Feig BW
, Pisters PW, Pollock RE, Lev D, Hunt KK,
Cormier JN
, Blazer DG, Lazar AJ, Xing Y, Askew RL, Feig BW, Pisters PW, Pollock RE, Lev D,
Hunt KK
, Cormier JN. Clinical outcomes of molecularly confirmed clear cell sarcoma from a single institution and in comparison with data from the Surveillance, Epidemiology, and End Results registry. Cancer. 2009 Jul 01; 115(13):2971-9.
PMID:
19402173
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Lazar AJ, Hajibashi S, Lev D,
Lazar AJ
, Hajibashi S, Lev D. Desmoid tumor: from surgical extirpation to molecular dissection. Curr Opin Oncol. 2009 Jul; 21(4):352-9.
PMID:
19436199
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Lahat G, Dhuka AR, Lahat S, Lazar AJ, Lewis VO,
Lin PP
, Feig B, Cormier JN, Hunt KK, Pisters PW, Pollock RE, Lev D, Lahat G, Dhuka AR, Lahat S,
Lazar AJ
,
Lewis VO
, Lin PP,
Feig B
,
Cormier JN
,
Hunt KK
, Pisters PW, Pollock RE, Lev D. Complete soft tissue sarcoma resection is a viable treatment option for select elderly patients. Ann Surg Oncol. 2009 Sep; 16(9):2579-86.
PMID:
19557478
.
Citations:
22
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Wang WL
, Mayordomo E, Zhang W, Hernandez VS, Tuvin D, Garcia L, Lev DC,
Lazar AJ
, López-Terrada D, Wang WL, Mayordomo E, Zhang W, Hernandez VS, Tuvin D, Garcia L, Lev DC, Lazar AJ, López-Terrada D, L?pez-Terrada D. Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts). Mod Pathol. 2009 Sep; 22(9):1201-9.
PMID:
19561568
.
Citations:
52
Fields:
Pat
Pathology
Translation:
Humans
Lahat G, Dhuka AR, Lahat S, Smith KD, Pollock RE,
Hunt KK
, Ravi V, Lazar AJ, Lev D, Lahat G, Dhuka AR, Lahat S, Smith KD, Pollock RE, Hunt KK, Ravi V,
Lazar AJ
, Lev D. Outcome of locally recurrent and metastatic angiosarcoma. Ann Surg Oncol. 2009 Sep; 16(9):2502-9.
PMID:
19551444
.
Citations:
18
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Subbiah V
, Anderson P, Lazar AJ, Burdett E, Raymond K, Ludwig JA, Subbiah V, Anderson P,
Lazar AJ
, Burdett E, Raymond K,
Ludwig JA
. Ewing's sarcoma: standard and experimental treatment options. Curr Treat Options Oncol. 2009 Apr; 10(1-2):126-40.
PMID:
19533369
.
Citations:
65
Fields:
Neo
Neoplasms
Translation:
Humans
Zou C, Smith KD, Liu J, Lahat G, Myers S,
Wang WL
, Zhang W,
McCutcheon IE
,
Slopis JM
, Lazar AJ, Pollock RE, Lev D, Zou C, Smith KD, Liu J, Lahat G, Myers S, Wang WL, Zhang W, McCutcheon IE, Slopis JM,
Lazar AJ
, Pollock RE, Lev D. Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg. 2009 Jun; 249(6):1014-22.
PMID:
19474676
.
Citations:
108
Fields:
Gen
General Surgery
Translation:
Humans
Pomahac B, Garcia JA, Lazar AJ, Tilney N, Orgill DP, Pomahac B, Garcia JA,
Lazar AJ
, Tilney N, Orgill DP. The skin allograft revisited: a potentially permanent wound coverage option in the critically ill patient. Plast Reconstr Surg. 2009 Jun; 123(6):1755-1758.
PMID:
19483575
.
Citations:
3
Fields:
Gen
General Surgery
Translation:
Humans
Zou CY, Smith KD, Zhu QS, Liu J,
McCutcheon IE
,
Slopis JM
, Meric-Bernstam F, Peng Z, Bornmann WG,
Mills GB
, Lazar AJ, Pollock RE, Lev D, Zou CY, Smith KD, Zhu QS, Liu J, McCutcheon IE, Slopis JM,
Meric-Bernstam F
, Peng Z,
Bornmann WG
, Mills GB,
Lazar AJ
, Pollock RE, Lev D. Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor. Mol Cancer Ther. 2009 May; 8(5):1157-68.
PMID:
19417153
.
Citations:
42
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
Wang WL
, Hornick JL, Mallipeddi R, Zelger BG, Rother JD, Yang D, Lev DC, Trent JC, Prieto VG, Brenn T, Robson A, Calonje E, Lazar AJ, Wang WL, Hornick JL, Mallipeddi R, Zelger BG, Rother JD, Yang D, Lev DC, Trent JC,
Prieto VG
, Brenn T, Robson A, Calonje E,
Lazar AJ
. Cutaneous and subcutaneous metastases of gastrointestinal stromal tumors: a series of 5 cases with molecular analysis. Am J Dermatopathol. 2009 May; 31(3):297-300.
PMID:
19384074
.
Citations:
7
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Lahat G, Lazar A, Wang X,
Wang WL
, Zhu QS,
Hunt KK
, Pollock RE, Lev D, Lahat G,
Lazar A
, Wang X, Wang WL, Zhu QS, Hunt KK, Pollock RE, Lev D. Increased vascular endothelial growth factor-C expression is insufficient to induce lymphatic metastasis in human soft-tissue sarcomas. Clin Cancer Res. 2009 Apr 15; 15(8):2637-46.
PMID:
19351758
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Liegl B, Hornick JL,
Lazar AJ
, Liegl B, Hornick JL, Lazar AJ. Contemporary pathology of gastrointestinal stromal tumors. Hematol Oncol Clin North Am. 2009 Feb; 23(1):49-68, vii-viii.
PMID:
19248970
.
Citations:
12
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Yang D, Wang S, Brooks C, Dong Z, Schoenlein PV, Kumar V, Ouyang X, Xiong H, Lahat G,
Hayes-Jordan A
,
Lazar A
, Pollock R, Lev D, Liu K, Yang D, Wang S, Brooks C, Dong Z, Schoenlein PV, Kumar V, Ouyang X, Xiong H, Lahat G, Hayes-Jordan A, Lazar A, Pollock R, Lev D, Liu K. IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression. Cancer Res. 2009 Feb 01; 69(3):1080-8.
PMID:
19155307
; PMCID:
PMC2633427
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
McAuliffe JC, Hunt KK,
Lazar AJ
, Choi H, Qiao W,
Thall P
, Pollock RE, Benjamin RS, Trent JC, McAuliffe JC,
Hunt KK
, Lazar AJ, Choi H, Qiao W, Thall P, Pollock RE, Benjamin RS, Trent JC. A randomized, phase II study of preoperative plus postoperative imatinib in GIST: evidence of rapid radiographic response and temporal induction of tumor cell apoptosis. Ann Surg Oncol. 2009 Apr; 16(4):910-9.
PMID:
18953611
; PMCID:
PMC5647649
.
Citations:
67
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Quintás-Cardama A, Lazar AJ, Woodman SE, Kim K, Ross M, Hwu P, Quintás-Cardama A,
Lazar AJ
,
Woodman SE
, Kim K,
Ross M
,
Hwu P
, Quint?s-Cardama A. Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib. Nat Clin Pract Oncol. 2008 Dec; 5(12):737-40.
PMID:
18936790
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Weaver J, Goldblum JR, Turner S, Tubbs RR,
Wang WL
, Lazar AJ, Rubin BP, Weaver J, Goldblum JR, Turner S, Tubbs RR, Wang WL,
Lazar AJ
, Rubin BP. Detection of MDM2 gene amplification or protein expression distinguishes sclerosing mesenteritis and retroperitoneal fibrosis from inflammatory well-differentiated liposarcoma. Mod Pathol. 2009 Jan; 22(1):66-70.
PMID:
18836421
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans