NANCY GORDON

TitleAssistant Professor
InstitutionMD Anderson
DepartmentPediatrics
Address7777 Knight Rd
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Singh A, Cheng D, Swaminathan J, Yang Y, Zheng Y, Gordon N, Gopalakrishnan V. REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma. Sci Rep. 2024 06 12; 14(1):13596. PMID: 38866867; PMCID: PMC11169471.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Truong DD, Weistuch C, Murgas KA, Admane P, King BL, Chauviere Lee J, Lamhamedi-Cherradi SE, Swaminathan J, Daw NC, Gordon N, Gopalakrishnan V, Gorlick RG, Somaiah N, Deasy JO, Mikos AG, Tannenbaum A, Ludwig J. Mapping the Single-cell Differentiation Landscape of Osteosarcoma. Clin Cancer Res. 2024 May 22. PMID: 38775859.
      Citations:    Fields:    
    3. Rav E, Maegawa S, Gopalakrishnan V, Gordon N. Overview of CD70 as a Potential Therapeutic Target for Osteosarcoma. J Immunol. 2023 10 01; 211(7):1067-1072. PMID: 37722095.
      Citations:    Fields:    Translation:Humans
    4. Truong DD, Lamhamedi-Cherradi SE, Porter RW, Krishnan S, Swaminathan J, Gibson A, Lazar AJ, Livingston JA, Gopalakrishnan V, Gordon N, Daw NC, Navin NE, Gorlick R, Ludwig JA. Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing. BMC Cancer. 2023 May 31; 23(1):488. PMID: 37254069; PMCID: PMC10230784.
      Citations: 1     Fields:    Translation:HumansCells
    5. Dao L, Ragoonanan D, Batth I, Satelli A, Foglesong J, Wang J, Zaky W, Gill JB, Liu D, Albert A, Gordon N, Huh W, Harrison D, Herzog C, Kleinerman E, Gorlick R, Daw N, Li S. Prognostic Value of Cell-Surface Vimentin-Positive CTCs in Pediatric Sarcomas. Front Oncol. 2021; 11:760267. PMID: 34956881; PMCID: PMC8695931.
      Citations:    
    6. Shi Y, Shen HM, Gopalakrishnan V, Gordon N. Epigenetic Regulation of Autophagy Beyond the Cytoplasm: A Review. Front Cell Dev Biol. 2021; 9:675599. PMID: 34195194; PMCID: PMC8237754.
      Citations: 1     
    7. Hennessy M, Wahba A, Felix K, Cabrera M, Segura MG, Kundra V, Ravoori MK, Stewart J, Kleinerman ES, Jensen VB, Gopalakrishnan V, Pena R, Quach P, Kim G, Madakamutil L, Overwijk WW, Zalevsky J, Gordon N, Kivim?e S. Bempegaldesleukin (BEMPEG; NKTR-214) efficacy as a single agent and in combination with checkpoint-inhibitor therapy in mouse models of osteosarcoma. Int J Cancer. 2021 04 15; 148(8):1928-1937. PMID: 33152115; PMCID: PMC7984260.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    8. Wolf-Dennen K, Gordon N, Kleinerman ES. Exosomal communication by metastatic osteosarcoma cells modulates alveolar macrophages to an M2 tumor-promoting phenotype and inhibits tumoricidal functions. Oncoimmunology. 2020; 9(1):1747677. PMID: 32313728; PMCID: PMC7153823.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    9. Hollomon MG, Patterson L, Santiago-O'Farrill J, Kleinerman ES, Gordon N. Knock down of Fas-Associated Protein with Death Domain (FADD) Sensitizes Osteosarcoma to TNFa-induced Cell Death. J Cancer. 2020; 11(7):1657-1667. PMID: 32194778; PMCID: PMC7052864.
      Citations: 4     
    10. Gordon N, Felix K, Daw NC. Aerosolized Chemotherapy for Osteosarcoma. Adv Exp Med Biol. 2020; 1257:67-73. PMID: 32483731.
      Citations: 1     Fields:    Translation:HumansAnimals
    11. Kiany S, Gordon N, Harrison D. The Histone Deacetylase Inhibitor Entinostat/Syndax 275 in Osteosarcoma. Adv Exp Med Biol. 2020; 1257:75-83. PMID: 32483732.
      Citations: 4     Fields:    Translation:Humans
    12. Nehme G, Gordon N. Autophagy in Osteosarcoma. Adv Exp Med Biol. 2020; 1258:167-175. PMID: 32767241; PMCID: PMC9131842.
      Citations: 2     Fields:    Translation:Humans
    13. Kennis BA, Michel KA, Brugmann WB, Laureano A, Tao RH, Somanchi SS, Einstein SA, Bravo-Alegria JB, Maegawa S, Wahba A, Kiany S, Gordon N, Silla L, Schellingerhout D, Khatua S, Zaky W, Sandberg D, Cooper L, Lee DA, Bankson JA, Gopalakrishnan V. Correction to: Monitoring of intracerebellarly-administered natural killer cells with fluorine-19 MRI. J Neurooncol. 2019 May; 142(3):409. PMID: 30968268.
      Citations:    Fields:    
    14. Kennis BA, Michel KA, Brugmann WB, Laureano A, Tao RH, Somanchi SS, Einstein SA, Bravo-Alegria JB, Maegawa S, Wahba A, Kiany S, Gordon N, Silla L, Schellingerhout D, Khatua S, Zaky W, Sandberg D, Cooper L, Lee DA, Bankson JA, Gopalakrishnan V. Monitoring of intracerebellarly-administered natural killer cells with fluorine-19 MRI. J Neurooncol. 2019 May; 142(3):395-407. PMID: 30788681.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    15. Dhupkar P, Gordon N, Stewart J, Kleinerman ES. Anti-PD-1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastases. Cancer Med. 2018 06; 7(6):2654-2664. PMID: 29733528; PMCID: PMC6010882.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    16. Livingston JA, Wang WL, Tsai JW, Lazar AJ, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M, Gordon NB, Kleinerman ES. Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol Cancer Ther. 2018 06; 17(6):1315-1323. PMID: 29592877; PMCID: PMC5984702.
      Citations: 9     Fields:    Translation:Humans
    17. Kleinerman ES, Yu L, Dao J, Hayes-Jordan AA, Lindsey B, Kawedia JD, Stewart J, Gordon N. Aerosol Gemcitabine after Amputation Inhibits Osteosarcoma Lung Metastases but Not Wound Healing. Sarcoma. 2018; 2018:3143096. PMID: 29610563; PMCID: PMC5828535.
      Citations: 2     
    18. Santiago-O'Farrill JM, Kleinerman ES, Hollomon MG, Livingston A, Wang WL, Tsai JW, Gordon NB. Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy. Oncotarget. 2018 Jan 05; 9(2):1602-1616. PMID: 29416717; PMCID: PMC5788585.
      Citations: 7     Fields:    
    19. Dhupkar P, Gordon N. Interleukin-2: Old and New Approaches to Enhance Immune-Therapeutic Efficacy. Adv Exp Med Biol. 2017; 995:33-51. PMID: 28321811.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    20. Kiany S, Gordon N. Aerosol Delivery of Interleukin-2 in Combination with Adoptive Transfer of Natural Killer Cells for the Treatment of Lung Metastasis: Methodology and Effect. Methods Mol Biol. 2016; 1441:285-95. PMID: 27177675.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    21. Guma SR, Lee DA, Ling Y, Gordon N, Kleinerman ES. Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis. Pediatr Blood Cancer. 2014 Aug; 61(8):1362-8. PMID: 24610870; PMCID: PMC4144337.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    22. O'Farrill JS, Gordon N. Autophagy in osteosarcoma. Adv Exp Med Biol. 2014; 804:147-60. PMID: 24924173.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    23. Hollomon MG, Gordon N, Santiago-O'Farrill JM, Kleinerman ES. Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells. BMC Cancer. 2013 Oct 26; 13:500. PMID: 24160177; PMCID: PMC3924338.
      Citations: 23     Fields:    Translation:AnimalsCells
    24. Guma SR, Lee DA, Yu L, Gordon N, Hughes D, Stewart J, Wang WL, Kleinerman ES. Natural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis. Pediatr Blood Cancer. 2014 Apr; 61(4):618-26. PMID: 24136885; PMCID: PMC4154381.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    25. Gordon N, Kleinerman ES. Aerosol therapy for the treatment of osteosarcoma lung metastases: targeting the Fas/FasL pathway and rationale for the use of gemcitabine. J Aerosol Med Pulm Drug Deliv. 2010 Aug; 23(4):189-96. PMID: 20528149; PMCID: PMC3133834.
      Citations: 18     Fields:    Translation:HumansAnimals
    26. Rodriguez CO, Crabbs TA, Wilson DW, Cannan VA, Skorupski KA, Gordon N, Koshkina N, Kleinerman E, Anderson PM. Aerosol gemcitabine: preclinical safety and in vivo antitumor activity in osteosarcoma-bearing dogs. J Aerosol Med Pulm Drug Deliv. 2010 Aug; 23(4):197-206. PMID: 19803732; PMCID: PMC2888930.
      Citations: 16     Fields:    Translation:Animals
    27. Gordon N, Kleinerman ES. The role of Fas/FasL in the metastatic potential of osteosarcoma and targeting this pathway for the treatment of osteosarcoma lung metastases. Cancer Treat Res. 2009; 152:497-508. PMID: 20213411.
      Citations: 20     Fields:    Translation:HumansAnimals
    28. Gordon N, Koshkina NV, Jia SF, Khanna C, Mendoza A, Worth LL, Kleinerman ES. Corruption of the Fas pathway delays the pulmonary clearance of murine osteosarcoma cells, enhances their metastatic potential, and reduces the effect of aerosol gemcitabine. Clin Cancer Res. 2007 Aug 01; 13(15 Pt 1):4503-10. PMID: 17671136; PMCID: PMC4503209.
      Citations: 36     Fields:    Translation:AnimalsCells
    29. Hahn KM, Johnson PH, Gordon N, Kuerer H, Middleton L, Ramirez M, Yang W, Perkins G, Hortobagyi GN, Theriault RL. Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Cancer. 2006 Sep 15; 107(6):1219-26. PMID: 16894524.
      Citations: 70     Fields:    Translation:HumansCTClinical Trials
    30. Gordon N, Arndt CA, Hawkins DS, Doherty DK, Inwards CY, Munsell MF, Stewart J, Koshkina NV, Kleinerman ES. Fas expression in lung metastasis from osteosarcoma patients. J Pediatr Hematol Oncol. 2005 Nov; 27(11):611-5. PMID: 16282894.
      Citations: 21     Fields:    Translation:HumansCells
    31. Gordon N, Mullen CA, Tran H, Worth L, Gomez Almaguer D, Chan KW. Fludarabine and once-daily intravenous busulfan for allogeneic bone marrow transplantation for Chediak-Higashi syndrome. J Pediatr Hematol Oncol. 2003 Oct; 25(10):824-6. PMID: 14528111.
      Citations: 3     Fields:    Translation:Humans
    32. Aerosol delivery of interleukin-2 in combination with adoptive transfer of natural killer cells for the treatment of lung metastasis. 285-295.
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