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MICHAEL O'REILLY

TitleAssociate Professor
InstitutionMD Anderson
DepartmentRadiation Oncology
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Corrigan KL, Xu T, Sasaki Y, Lin R, Chen AB, Welsh JW, Lin SH, Chang JY, Ning MS, Gandhi S, O'Reilly MS, Gay CM, Altan M, Lu C, Cascone T, Koutroumpakis E, Sheshadri A, Zhang X, Liao L, Zhu XR, Heymach JV, Nguyen QN, Liao Z, Xu T. Survival outcomes and toxicity of adjuvant immunotherapy after definitive concurrent chemotherapy with proton beam radiation therapy for patients with inoperable locally advanced non-small cell lung carcinoma. Radiother Oncol. 2024 Apr; 193:110121. PMID: 38311031; PMCID: PMC10947851.
      Citations:    Fields:    Translation:Humans
    2. Liu Y, Yao L, Kalhor N, Carter BW, Altan M, Blumenschein G, Byers LA, Fossella F, Gibbons DL, Kurie JM, Lu C, Skoulidis F, Chang JY, Liao Z, Gomez DR, O'Reilly M, Heymach JV, Tsao AS, Lin SH. Final efficacy outcomes of atezolizumab with chemoradiation for unresectable NSCLC: The phase II DETERRED trial. Lung Cancer. 2022 Oct 29; 174:112-117. PMID: 36371941.
      Citations:    Fields:    
    3. Hui D, Puac V, Shelal Z, Dev R, Hanneman SK, Jennings K, Ma H, Urbauer DL, Shete S, Fossella F, Liao Z, Blumenschein G, Chang JY, O'Reilly M, Gandhi SJ, Tsao A, Mahler DA, Bruera E. Effect of dexamethasone on dyspnoea in patients with cancer (ABCD): a parallel-group, double-blind, randomised, controlled trial. Lancet Oncol. 2022 10; 23(10):1321-1331. PMID: 36087590; PMCID: PMC10618956.
      Citations:    
    4. Lin SH, Lin HY, Verma V, Xu-Welliver M, Thall PF, Yao L, Kim PY, Gombos DS, Kawedia JD, Komaki R, Gomez DR, Nguyen QN, O'Reilly MS, Lu C, Fossella FV, Skoulidis F, Zhang J, Tsao AS, Heymach JV, Blumenschein GR. Phase I Trial of Definitive Concurrent Chemoradiotherapy and Trametinib for KRAS-Mutated Non-Small Cell Lung Cancer. Cancer Treat Res Commun. 2022; 30:100514. PMID: 35051703; PMCID: PMC9259763.
      Citations:    Fields:    
    5. Chang JY, Mehran RJ, Feng L, Verma V, Liao Z, Welsh JW, Lin SH, O'Reilly MS, Jeter MD, Balter PA, McRae SE, Berry D, Heymach JV, Roth JA, STARS Lung Cancer Trials Group. Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery. Lancet Oncol. 2021 10; 22(10):1448-1457. PMID: 34529930; PMCID: PMC8521627.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    6. Jing W, Liu Y, Zhu H, Welsh J, Gandhi S, Jeter M, Nguyen Q, Chen AB, O'Reilly M, Liao Z, Chang JY, Lee P, Lin SH. Prognosis of severe lymphopenia after postoperative radiotherapy in non-small cell lung cancer: Results of a long-term follow up study. Clin Transl Radiat Oncol. 2021 May; 28:54-61. PMID: 33778173; PMCID: PMC7985216.
      Citations: 2     
    7. Brady Z, Garrahy A, Carthy C, O'Reilly MW, Thompson CJ, Sherlock M, Agha A, Javadpour M. Outcomes of endoscopic transsphenoidal surgery for Cushing's disease. BMC Endocr Disord. 2021 Mar 03; 21(1):36. PMID: 33658018; PMCID: PMC7931517.
      Citations:    Fields:    Translation:Humans
    8. Samson P, Ning MS, Shaverdian N, Shepherd AF, Gomez DR, McGinnis GJ, Nitsch PL, Chmura S, O'Reilly MS, Lee P, Chang JY, Robinson C, Lin SH. Clinical and Radiographic Presentations of COVID-19 Among Patients Receiving Radiation Therapy for Thoracic Malignancies. Adv Radiat Oncol. 2020 Jul-Aug; 5(4):700-704. PMID: 32395673; PMCID: PMC7212983.
      Citations: 5     
    9. Mesko S, Ning MS, Lakomy D, Verma V, Chang JY, O'Reilly M, Jeter MD, Gandhi SJ, Lin SH, Nguyen QN, Liao Z, Welsh J, Chen AB, Hahn S, Gomez DR. Thoracic Radiation Oncology Clinical Trial Accrual and Reasons for Nonenrollment: Results of a Large, Prospective, Multiyear Analysis. Int J Radiat Oncol Biol Phys. 2020 08 01; 107(5):897-908. PMID: 32360653.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    10. McGinnis GJ, Ning MS, Nitsch PL, O'Reilly MS, McAleer MF, Koong AC, Chang JY. Rapid Detection of Asymptomatic Coronavirus Disease 2019 by Computed Tomography Image Guidance for Stereotactic Ablative Radiotherapy. J Thorac Oncol. 2020 06; 15(6):1085-1087. PMID: 32311499; PMCID: PMC7162784.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    11. Chortis V, Bancos I, Nijman T, Gilligan LC, Taylor AE, Ronchi CL, O'Reilly MW, Asia M, Perotti P, Quinkler M, Canu L, Paiva I, Kastelan D, Dennedy MC, Sherlock M, Ambroziak U, Vassiliadi D, Deeks JJ, Biehl M, Arlt W, Schreiner J, Riester A, Lib? R, Bugalho MJ, Bertherat J, Beuschlein F, Fassnacht M. Urine Steroid Metabolomics as a Novel Tool for Detection of Recurrent Adrenocortical Carcinoma. J Clin Endocrinol Metab. 2020 03 01; 105(3). PMID: 31665449; PMCID: PMC7112967.
      Citations: 13     Fields:    Translation:Humans
    12. Lin SH, Lin Y, Yao L, Kalhor N, Carter BW, Altan M, Blumenschein G, Byers LA, Fossella F, Gibbons DL, Kurie JM, Lu C, Simon G, Skoulidis F, Chang JY, Jeter MD, Liao Z, Gomez DR, O'Reilly M, Papadimitrakopoulou V, Thall P, Heymach JV, Tsao AS. Phase II Trial of Concurrent Atezolizumab With Chemoradiation for Unresectable NSCLC. J Thorac Oncol. 2020 02; 15(2):248-257. PMID: 31778797.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    13. Nguyen QN, Chun SG, Chow E, Komaki R, Liao Z, Zacharia R, Szeto BK, Welsh JW, Hahn SM, Fuller CD, Moon BS, Bird JE, Satcher R, Lin PP, Jeter M, O'Reilly MS, Lewis VO. Single-Fraction Stereotactic vs Conventional Multifraction Radiotherapy for Pain Relief in Patients With Predominantly Nonspine Bone Metastases: A Randomized Phase 2 Trial. JAMA Oncol. 2019 06 01; 5(6):872-878. PMID: 31021390; PMCID: PMC6487911.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    14. Morris-Schaffer K, Sobolewski M, Welle K, Conrad K, Yee M, O'Reilly MA, Cory-Slechta DA. Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles. Neurotoxicol Teratol. 2018 Nov - Dec; 70:51-59. PMID: 30316930; PMCID: PMC6245952.
      Citations: 2     Fields:    Translation:Animals
    15. Brooks ED, Sun B, Feng L, Verma V, Zhao L, Gomez DR, Liao Z, Jeter M, O'Reilly M, Welsh JW, Nguyen QN, Erasmus JJ, Eapen G, Ahrar K, Antonoff MB, Hahn SM, Heymach JV, Rice DC, Chang JY. Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer. JAMA Netw Open. 2018 08 03; 1(4):e181390. PMID: 30646121; PMCID: PMC6324276.
      Citations: 17     Fields:    Translation:Humans
    16. Liao Z, Lee JJ, Komaki R, Gomez DR, O'Reilly MS, Fossella FV, Blumenschein GR, Heymach JV, Vaporciyan AA, Swisher SG, Allen PK, Choi NC, DeLaney TF, Hahn SM, Cox JD, Lu CS, Mohan R. Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer. J Clin Oncol. 2018 06 20; 36(18):1813-1822. PMID: 29293386; PMCID: PMC6008104.
      Citations: 98     Fields:    Translation:Humans
    17. Jeter MD, Gomez D, Nguyen QN, Komaki R, Zhang X, Zhu X, O'Reilly M, Fossella FV, Xu T, Wei X, Wang H, Yang W, Tsao A, Mohan R, Liao Z. Simultaneous Integrated Boost for Radiation Dose Escalation to the Gross Tumor Volume With Intensity Modulated (Photon) Radiation Therapy or Intensity Modulated Proton Therapy and Concurrent Chemotherapy for Stage II to III Non-Small Cell Lung Cancer: A Phase 1 Study. Int J Radiat Oncol Biol Phys. 2018 03 01; 100(3):730-737. PMID: 29248169; PMCID: PMC5846341.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    18. Chang JY, Verma V, Li M, Zhang W, Komaki R, Lu C, Allen PK, Liao Z, Welsh J, Lin SH, Gomez D, Jeter M, O'Reilly M, Zhu RX, Zhang X, Li H, Mohan R, Heymach JV, Vaporciyan AA, Hahn S, Cox JD. Proton Beam Radiotherapy and Concurrent Chemotherapy for Unresectable Stage III Non-Small Cell Lung Cancer: Final Results of a Phase 2 Study. JAMA Oncol. 2017 08 10; 3(8):e172032. PMID: 28727865; PMCID: PMC5824219.
      Citations: 58     Fields:    Translation:HumansCTClinical Trials
    19. Tampourlou M, Ntali G, Ahmed S, Arlt W, Ayuk J, Byrne JV, Chavda S, Cudlip S, Gittoes N, Grossman A, Mitchell R, O'Reilly MW, Paluzzi A, Toogood A, Wass JAH, Karavitaki N. Outcome of Nonfunctioning Pituitary Adenomas That Regrow After Primary Treatment: A Study From Two Large UK Centers. J Clin Endocrinol Metab. 2017 06 01; 102(6):1889-1897. PMID: 28323946.
      Citations: 22     Fields:    Translation:Humans
    20. Sun B, Brooks ED, Komaki RU, Liao Z, Jeter MD, McAleer MF, Allen PK, Balter PA, Welsh JD, O'Reilly MS, Gomez D, Hahn SM, Roth JA, Mehran RJ, Heymach JV, Chang JY. 7-year follow-up after stereotactic ablative radiotherapy for patients with stage I non-small cell lung cancer: Results of a phase 2 clinical trial. Cancer. 2017 Aug 15; 123(16):3031-3039. PMID: 28346656; PMCID: PMC5544582.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    21. Sun B, Brooks ED, Komaki R, Liao Z, Jeter M, McAleer M, Balter PA, Welsh JD, O'Reilly M, Gomez D, Hahn SM, Sepesi B, Rice DC, Heymach JV, Chang JY. Long-Term Outcomes of Salvage Stereotactic Ablative?Radiotherapy for Isolated Lung Recurrence of Non-Small Cell Lung Cancer: A Phase II Clinical Trial. J Thorac Oncol. 2017 06; 12(6):983-992. PMID: 28259750; PMCID: PMC5881570.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    22. Chang JY, Zhang W, Komaki R, Choi NC, Chan S, Gomez D, O'Reilly M, Jeter M, Gillin M, Zhu X, Zhang X, Mohan R, Swisher S, Hahn S, Cox JD. Long-term outcome of phase I/II prospective study of dose-escalated proton therapy for early-stage non-small cell lung cancer. Radiother Oncol. 2017 02; 122(2):274-280. PMID: 28139305; PMCID: PMC5319887.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    23. Brooks ED, Sun B, Zhao L, Komaki R, Liao Z, Jeter M, Welsh JW, O'Reilly MS, Gomez DR, Hahn SM, Heymach JV, Rice DC, Chang JY. Stereotactic Ablative Radiation Therapy is Highly Safe and Effective for Elderly Patients With Early-stage Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2017 07 15; 98(4):900-907. PMID: 28258887; PMCID: PMC5881567.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    24. O'Reilly MW, Reulen RC, Gupta S, Thompson CA, Dineen R, Goulden EL, Bugg G, Pearce H, Toogood AA, Gittoes NJ, Mitchell R, Thompson CJ, Ayuk J. ACTH and gonadotropin deficiencies predict mortality in patients treated for nonfunctioning pituitary adenoma: long-term follow-up of 519 patients in two large European centres. Clin Endocrinol (Oxf). 2016 Nov; 85(5):748-756. PMID: 27327840; PMCID: PMC5082557.
      Citations: 11     Fields:    Translation:Humans
    25. Wang XS, Shi Q, Williams LA, Komaki R, Gomez DR, Lin SH, Chang JY, O'Reilly MS, Bokhari RH, Cox JD, Mohan R, Cleeland CS, Liao Z. Prospective Study of Patient-Reported Symptom Burden in Patients With Non-Small-Cell Lung Cancer Undergoing Proton or Photon Chemoradiation Therapy. J Pain Symptom Manage. 2016 05; 51(5):832-8. PMID: 26891607; PMCID: PMC4875833.
      Citations: 14     Fields:    Translation:Humans
    26. Munir S, Chang JH, Salahudeen SR, Baranchuk A, Morris C, O'Reilly M, Pal RS. Atrial thrombi detection prior to pulmonary vein isolation: diagnostic accuracy of cardiac computed tomography versus transesophageal echocardiography. Cardiol J. 2015; 22(5):576-82. PMID: 25786766.
      Citations: 2     Fields:    Translation:Humans
    27. Xu T, Liao Z, O'Reilly MS, Levy LB, Welsh JW, Wang LE, Lin SH, Komaki R, Liu Z, Wei Q, Gomez DR. Serum inflammatory miRNAs predict radiation esophagitis in patients receiving definitive radiochemotherapy for non-small cell lung cancer. Radiother Oncol. 2014 Dec; 113(3):379-84. PMID: 25466375.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    28. Kalifa L, Gewandter JS, Staversky RJ, Sia EA, Brookes PS, O'Reilly MA. DNA double-strand breaks activate ATM independent of mitochondrial dysfunction in A549 cells. Free Radic Biol Med. 2014 Oct; 75:30-9. PMID: 25048973; PMCID: PMC4171189.
      Citations: 5     Fields:    Translation:HumansCells
    29. Gladish GW, Wei X, Kotamarti KR, Allen PK, Cox JD, O'Reilly MS, Erasmus JJ, Fossella FV, Komaki R, Gomez DR. Prognostic value of positron emission tomography/computed tomography findings in limited-stage small cell lung cancer before chemoradiation therapy. Am J Clin Oncol. 2014 Feb; 37(1):77-80. PMID: 23111360.
      Citations: 4     Fields:    Translation:Humans
    30. Wang H, Liao Z, Zhuang Y, Xu T, Nguyen QN, Levy LB, O'Reilly M, Gold KA, Gomez DR. Do angiotensin-converting enzyme inhibitors reduce the risk of symptomatic radiation pneumonitis in patients with non-small cell lung cancer after definitive radiation therapy? Analysis of a single-institution database. Int J Radiat Oncol Biol Phys. 2013 Dec 01; 87(5):1071-7. PMID: 24161424; PMCID: PMC4162095.
      Citations: 13     Fields:    Translation:Humans
    31. Shirvani SM, Juloori A, Allen PK, Komaki R, Liao Z, Gomez D, O'Reilly M, Welsh J, Papadimitrakopoulou V, Cox JD, Chang JY. Comparison of 2 common radiation therapy techniques for definitive treatment of small cell lung cancer. Int J Radiat Oncol Biol Phys. 2013 Sep 01; 87(1):139-47. PMID: 23920393.
      Citations: 16     Fields:    Translation:Humans
    32. Baird BN, Schliekelman MJ, Ahn YH, Chen Y, Roybal JD, Gill BJ, Mishra DK, Erez B, O'Reilly M, Yang Y, Patel M, Liu X, Thilaganathan N, Larina IV, Dickinson ME, West JL, Gibbons DL, Liu DD, Kim MP, Hicks JM, Wistuba II, Hanash SM, Kurie JM. Fibulin-2 is a driver of malignant progression in lung adenocarcinoma. PLoS One. 2013; 8(6):e67054. PMID: 23785517; PMCID: PMC3677922.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    33. Isobe T, Onn A, Morgensztern D, Wu W, Shintani T, Itasaka S, Shibuya K, Koo PJ, O'Reilly MS, Herbst RS, Jacoby JJ. Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer. J Thorac Oncol. 2013 Feb; 8(2):140-6. PMID: 23328546.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    34. Saintigny P, Massarelli E, Lin S, Ahn YH, Chen Y, Goswami S, Erez B, O'Reilly MS, Liu D, Lee JJ, Zhang L, Ping Y, Behrens C, Solis Soto LM, Heymach JV, Kim ES, Herbst RS, Lippman SM, Wistuba II, Hong WK, Kurie JM, Koo JS. CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma. Cancer Res. 2013 Jan 15; 73(2):571-82. PMID: 23204236; PMCID: PMC3548940.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    35. Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh JW, O'Reilly MS, Hofstetter WL, Ajani JA, Komaki R, Cox JD, Sandulache VC, Myers JN, Guerrero TM. Metformin use and improved response to therapy in esophageal adenocarcinoma. Acta Oncol. 2013 Jun; 52(5):1002-9. PMID: 22950385.
      Citations: 41     Fields:    Translation:Humans
    36. Xu T, Wei Q, Lopez Guerra JL, Wang LE, Liu Z, Gomez D, O'Reilly M, Lin SH, Zhuang Y, Levy LB, Mohan R, Zhou H, Liao Z. HSPB1 gene polymorphisms predict risk of mortality for US patients after radio(chemo)therapy for non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2012 Oct 01; 84(2):e229-35. PMID: 22608953; PMCID: PMC3426644.
      Citations: 6     Fields:    Translation:Humans
    37. Yin M, Liao Z, Yuan X, Guan X, O'Reilly MS, Welsh J, Wang LE, Wei Q. Polymorphisms of the vascular endothelial growth factor gene and severe radiation pneumonitis in non-small cell lung cancer patients treated with definitive radiotherapy. Cancer Sci. 2012 May; 103(5):945-50. PMID: 22320189; PMCID: PMC3337362.
      Citations: 12     Fields:    Translation:Humans
    38. Takahashi O, Komaki R, Smith PD, Ryan A, Bekele BN, Wistuba II, Korshunova MV, Biernacka A, Erez B, Hosho K, Herbst RS, O'Reilly MS, J?rgensmeier JM, Jacoby JJ. Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis. Clin Cancer Res. 2012 Mar 15; 18(6):1641-54. PMID: 22275507; PMCID: PMC3306446.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    39. Komaki R, Wei X, Allen PK, Liao Z, Milas L, Cox JD, O'Reilly MS, Chang JY, McAleer MF, Jeter M, Blumenschein GR, Kies MS. Phase I study of celecoxib with concurrent irinotecan, Cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer. Front Oncol. 2011; 1:52. PMID: 22649768; PMCID: PMC3355954.
      Citations: 5     
    40. Yin M, Liao Z, Liu Z, Wang LE, O'Reilly M, Gomez D, Li M, Komaki R, Wei Q. Genetic variants of the nonhomologous end joining gene LIG4 and severe radiation pneumonitis in nonsmall cell lung cancer patients treated with definitive radiotherapy. Cancer. 2012 Jan 15; 118(2):528-35. PMID: 21717429; PMCID: PMC3184314.
      Citations: 28     Fields:    Translation:Humans
    41. McGrath-Morrow SA, Lauer T, Collaco JM, Yee M, O'Reilly M, Mitzner W, Neptune E, Wise R, Biswal S. Neonatal hyperoxia contributes additively to cigarette smoke-induced chronic obstructive pulmonary disease changes in adult mice. Am J Respir Cell Mol Biol. 2011 Sep; 45(3):610-6. PMID: 21239606; PMCID: PMC3175575.
      Citations: 17     Fields:    Translation:Animals
    42. Wu YC, O'Reilly MA. Bcl-X(L) is the primary mediator of p21 protection against hyperoxia-induced cell death. Exp Lung Res. 2011 Mar; 37(2):82-91. PMID: 21128858; PMCID: PMC3749887.
      Citations: 9     Fields:    Translation:HumansCells
    43. Guan X, Yin M, Wei Q, Zhao H, Liu Z, Wang LE, Yuan X, O'Reilly MS, Komaki R, Liao Z. Genotypes and haplotypes of the VEGF gene and survival in locally advanced non-small cell lung cancer patients treated with chemoradiotherapy. BMC Cancer. 2010 Aug 16; 10:431. PMID: 20712888; PMCID: PMC2939547.
      Citations: 14     Fields:    Translation:Humans
    44. Erez B, Korshunova MV, Williams RR, Furutani K, Takahashi O, Kirkpatrick L, Lippman SM, Powis G, O'Reilly MS, Herbst RS, Jacoby JJ. Treatment with HIF-1alpha antagonist PX-478 inhibits progression and spread of orthotopic human small cell lung cancer and lung adenocarcinoma in mice. J Thorac Oncol. 2010 Jul; 5(7):940-9. PMID: 20512076; PMCID: PMC3782111.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    45. McGovern SL, Liao Z, Bucci MK, McAleer MF, Jeter MD, Chang JY, O'Reilly MS, Cox JD, Allen PK, Komaki R. Is sex associated with the outcome of patients treated with radiation for nonsmall cell lung cancer? Cancer. 2009 Jul 15; 115(14):3233-42. PMID: 19472405.
      Citations: 8     Fields:    Translation:Humans
    46. O'Reilly MS. The interaction of radiation therapy and antiangiogenic therapy. Cancer J. 2008 Jul-Aug; 14(4):207-13. PMID: 18677126.
      Citations: 4     Fields:    Translation:Humans
    47. Wu W, O'Reilly MS, Langley RR, Tsan RZ, Baker CH, Bekele N, Tang XM, Onn A, Fidler IJ, Herbst RS. Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice. Mol Cancer Ther. 2007 Oct; 6(10):2652-63. PMID: 17913856.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    48. O'Reilly MS. Antiangiogenic antithrombin. Semin Thromb Hemost. 2007 Oct; 33(7):660-6. PMID: 18000792.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    49. Shibuya K, Komaki R, Shintani T, Itasaka S, Ryan A, Milas L, Ang K, Herbst RS, O'Reilly MS, J?rgensmeier JM. Targeted therapy against VEGFR and EGFR with ZD6474 enhances the therapeutic efficacy of irradiation in an orthotopic model of human non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1534-43. PMID: 17889445; PMCID: PMC2151850.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    50. Itasaka S, Komaki R, Herbst RS, Shibuya K, Shintani T, Hunter NR, Onn A, Bucana CD, Milas L, Ang KK, O'Reilly MS. Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice. Int J Radiat Oncol Biol Phys. 2007 Mar 01; 67(3):870-8. PMID: 17293237; PMCID: PMC1976280.
      Citations: 24     Fields:    Translation:Animals
    51. Herbst RS, Heymach JV, O'Reilly MS, Onn A, Ryan AJ. Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis. Expert Opin Investig Drugs. 2007 Feb; 16(2):239-49. PMID: 17243944.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    52. Wu W, Onn A, Isobe T, Itasaka S, Langley RR, Shitani T, Shibuya K, Komaki R, Ryan AJ, Fidler IJ, Herbst RS, O'Reilly MS. Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade. Mol Cancer Ther. 2007 Feb; 6(2):471-83. PMID: 17308046.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    53. O'Reilly MS. Antiangiogenesis and vascular endothelial growth factor/vascular endothelial growth factor receptor targeting as part of a combined-modality approach to the treatment of cancer. Int J Radiat Oncol Biol Phys. 2007; 69(2 Suppl):S64-6. PMID: 17848299; PMCID: PMC2092454.
      Citations: 7     Fields:    
    54. Gehen SC, Vitiello PF, Bambara RA, Keng PC, O'Reilly MA. Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2007 Mar; 292(3):L716-24. PMID: 17085526.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    55. Yee M, Vitiello PF, Roper JM, Staversky RJ, Wright TW, McGrath-Morrow SA, Maniscalco WM, Finkelstein JN, O'Reilly MA. Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development. Am J Physiol Lung Cell Mol Physiol. 2006 Nov; 291(5):L1101-11. PMID: 16861382.
      Citations: 79     Fields:    Translation:Animals
    56. Crane CH, Ellis LM, Abbruzzese JL, Amos C, Xiong HQ, Ho L, Evans DB, Tamm EP, Ng C, Pisters PW, Charnsangavej C, Delclos ME, O'Reilly M, Lee JE, Wolff RA. Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer. J Clin Oncol. 2006 Mar 01; 24(7):1145-51. PMID: 16505434.
      Citations: 57     Fields:    Translation:HumansCTClinical Trials
    57. O'Reilly MS. Radiation combined with antiangiogenic and antivascular agents. Semin Radiat Oncol. 2006 Jan; 16(1):45-50. PMID: 16378906.
      Citations: 19     Fields:    Translation:Humans
    58. Marcus K, Johnson M, Adam RM, O'Reilly MS, Donovan M, Atala A, Freeman MR, Soker S. Tumor cell-associated neuropilin-1 and vascular endothelial growth factor expression as determinants of tumor growth in neuroblastoma. Neuropathology. 2005 Sep; 25(3):178-87. PMID: 16193833.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    59. Boo LM, Lin HH, Chung V, Zhou B, Louie SG, O'Reilly MA, Yen Y, Ann DK. High mobility group A2 potentiates genotoxic stress in part through the modulation of basal and DNA damage-dependent phosphatidylinositol 3-kinase-related protein kinase activation. Cancer Res. 2005 Aug 01; 65(15):6622-30. PMID: 16061642.
      Citations: 25     Fields:    Translation:HumansCells
    60. Mazzatti DJ, Lee YJ, Helt CE, O'Reilly MA, Keng PC. p53 modulates radiation sensitivity independent of p21 transcriptional activation. Am J Clin Oncol. 2005 Feb; 28(1):43-50. PMID: 15685034.
      Citations: 8     Fields:    Translation:HumansCells
    61. Roper JM, Gehen SC, Staversky RJ, Hollander MC, Fornace AJ, O'Reilly MA. Loss of Gadd45a does not modify the pulmonary response to oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2005 Apr; 288(4):L663-71. PMID: 15653712.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    62. Onn A, Isobe T, Wu W, Itasaka S, Shintani T, Shibuya K, Kenji Y, O'reilly MS, Fidler IJ, Herbst RS. Epidermal growth factor receptor tyrosine kinase inhibitor does not improve paclitaxel effect in an orthotopic mouse model of lung cancer. Clin Cancer Res. 2004 Dec 15; 10(24):8613-9. PMID: 15623645.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    63. Raut CP, Takamori RK, Davis DW, Sweeney-Gotsch B, O'Reilly MS, McConkey DJ. Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer. Cancer Biol Ther. 2004 Jul; 3(7):679-87. PMID: 15197351.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    64. McDonald DM, Teicher BA, Stetler-Stevenson W, Ng SS, Figg WD, Folkman J, Hanahan D, Auerbach R, O'Reilly M, Herbst R, Cheresh D, Gordon M, Eggermont A, Libutti SK. Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring. J Immunother. 2004 Mar-Apr; 27(2):161-75. PMID: 14770088.
      Citations: 4     Fields:    Translation:HumansAnimals
    65. Burney RE, Prabhu MA, Greenfield ML, Shanks A, O'Reilly M. Comparison of spinal vs general anesthesia via laryngeal mask airway in inguinal hernia repair. Arch Surg. 2004 Feb; 139(2):183-7. PMID: 14769578.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    66. McLean S, O'Reilly M, Doyle M, O Rathaille M. Improving Door-to-Drug time and ST segment resolution in AMI by moving thrombolysis administration to the Emergency Department. Accid Emerg Nurs. 2004 Jan; 12(1):2-9. PMID: 14700564.
      Citations: 5     Fields:    Translation:Humans
    67. Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O'Reilly MS, Hong WK, Fidler IJ, Putnam JB, Herbst RS. Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer. Clin Cancer Res. 2004 Jan 01; 10(1 Pt 1):136-43. PMID: 14734462.
      Citations: 43     Fields:    Translation:HumansCells
    68. Davis DW, Shen Y, Mullani NA, Wen S, Herbst RS, O'Reilly M, Abbruzzese JL, McConkey DJ. Quantitative analysis of biomarkers defines an optimal biological dose for recombinant human endostatin in primary human tumors. Clin Cancer Res. 2004 Jan 01; 10(1 Pt 1):33-42. PMID: 14734449.
      Citations: 8     Fields:    Translation:HumansCells
    69. Onn A, Isobe T, Itasaka S, Wu W, O'Reilly MS, Ki Hong W, Fidler IJ, Herbst RS. Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice. Clin Cancer Res. 2003 Nov 15; 9(15):5532-9. PMID: 14654533.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    70. Herbst RS, O'Reilly MS. The rationale and potential of combining novel biologic therapies with radiotherapy: focus on non-small cell lung cancer. Semin Oncol. 2003 Aug; 30(4 Suppl 9):113-23. PMID: 12908142.
      Citations: 1     Fields:    Translation:Humans
    71. Camphausen K, Moses MA, Sproull M, Beecken WD, Folkman J, O'Reilly MS, M?nard C. Radiation abscopal antitumor effect is mediated through p53. Cancer Res. 2003 Apr 15; 63(8):1990-3. PMID: 12702593.
      Citations: 98     Fields:    Translation:AnimalsCells
    72. Greene AK, Wiener S, Puder M, Yoshida A, Shi B, Perez-Atayde AR, Efstathiou JA, Holmgren L, Adamis AP, Rupnick M, Folkman J, O'Reilly MS. Endothelial-directed hepatic regeneration after partial hepatectomy. Ann Surg. 2003 Apr; 237(4):530-5. PMID: 12677150; PMCID: PMC1514466.
      Citations: 40     Fields:    Translation:AnimalsCells
    73. Howlett JG, Johnstone DE, Sketris I, O'Reilly M, Horne GS, Cox JL, Improving Cardiovascular Outcomes in Nova Scotia investigators. Identifying opportunities to address the congestive heart failure burden: the Improving Cardiovascular Outcomes in Nova Scotia (ICONS) study. Can J Cardiol. 2003 Mar 31; 19(4):439-44. PMID: 12704493.
      Citations: 5     Fields:    Translation:Humans
    74. O'Reilly MS. Therapeutic strategies using inhibitors of angiogenesis. Methods Mol Biol. 2003; 223:599-634. PMID: 12777753.
      Citations: 1     Fields:    Translation:HumansAnimals
    75. Rancourt RC, Hayes DD, Chess PR, Keng PC, O'Reilly MA. Growth arrest in G1 protects against oxygen-induced DNA damage and cell death. J Cell Physiol. 2002 Oct; 193(1):26-36. PMID: 12209877.
      Citations: 16     Fields:    Translation:AnimalsCells
    76. Herbst RS, Hess KR, Tran HT, Tseng JE, Mullani NA, Charnsangavej C, Madden T, Davis DW, McConkey DJ, O'Reilly MS, Ellis LM, Pluda J, Hong WK, Abbruzzese JL. Phase I study of recombinant human endostatin in patients with advanced solid tumors. J Clin Oncol. 2002 Sep 15; 20(18):3792-803. PMID: 12228199.
      Citations: 55     Fields:    Translation:HumansCTClinical Trials
    77. Herbst RS, Mullani NA, Davis DW, Hess KR, McConkey DJ, Charnsangavej C, O'Reilly MS, Kim HW, Baker C, Roach J, Ellis LM, Rashid A, Pluda J, Bucana C, Madden TL, Tran HT, Abbruzzese JL. Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin. J Clin Oncol. 2002 Sep 15; 20(18):3804-14. PMID: 12228200.
      Citations: 37     Fields:    Translation:HumansCTClinical Trials
    78. Ambati BK, Joussen AM, Ambati J, Moromizato Y, Guha C, Javaherian K, Gillies S, O'Reilly MS, Adamis AP. Angiostatin inhibits and regresses corneal neovascularization. Arch Ophthalmol. 2002 Aug; 120(8):1063-8. PMID: 12149060.
      Citations: 18     Fields:    Translation:Animals
    79. O'Reilly MS. The combination of antiangiogenic therapy with other modalities. Cancer J. 2002 May-Jun; 8 Suppl 1:S89-99. PMID: 12075706.
      Citations: 8     Fields:    Translation:Humans
    80. Claesson-Welsh L, Welsh M, Ito N, Anand-Apte B, Soker S, Zetter B, O'Reilly M, Folkman J. Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD. Proc Natl Acad Sci U S A. 1998 May 12; 95(10):5579-83. PMID: 9576925; PMCID: PMC20420.
      Citations: 59     Fields:    Translation:HumansCells
    81. Wu Z, O'Reilly MS, Folkman J, Shing Y. Suppression of tumor growth with recombinant murine angiostatin. Biochem Biophys Res Commun. 1997 Jul 30; 236(3):651-4. PMID: 9245707.
      Citations: 11     Fields:    Translation:AnimalsCells
    82. Cao Y, Ji RW, Davidson D, Schaller J, Marti D, McCance SG, O'Reilly MS, Folkman J, S?hndel S, Llin?s M. Kringle domains of human angiostatin. Characterization of the anti-proliferative activity on endothelial cells. J Biol Chem. 1996 Nov 15; 271(46):29461-7. PMID: 8910613.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    83. Parangi S, O'Reilly M, Christofori G, Holmgren L, Grosfeld J, Folkman J, Hanahan D. Antiangiogenic therapy of transgenic mice impairs de novo tumor growth. Proc Natl Acad Sci U S A. 1996 Mar 05; 93(5):2002-7. PMID: 8700875; PMCID: PMC39899.
      Citations: 73     Fields:    Translation:AnimalsCells
    84. Preclinical and clinical studies of recombinant human endostatin. European Journal of Cancer. 37.
    85. Erratum. Journal of Clinical Investigation. 102:2028.
    86. Phase I study of celecoxib with concurrent irinotecan, cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer. Frontiers in Oncology. 1.
    87. Prospective Study of Patient-Reported Symptom Burden in Patients With Non-Small-Cell Lung Cancer Undergoing Proton or Photon Chemoradiation Therapy. Journal of Pain and Symptom Management.
    88. Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer (Cancer Biology and Therapy (2004) 3, 7, (679-87). Cancer Biology and Therapy. 8:984.
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