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MICHAEL O'REILLY

TitleAssociate Professor
InstitutionMD Anderson
DepartmentRadiation Oncology
Address1400 Pressler St
Houston TX 77030-4008
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Warren R, O'Reilly MA. An Elusive Fox that Suppresses Scgb1a1 in Asthma Has Been Found. Am J Respir Cell Mol Biol. 2019 Feb 06. PMID: 30726101.
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    2. McGrath-Morrow SA, Ndeh R, Collaco JM, Rothblum-Oviatt C, Wright J, O'Reilly MA, Singer BD, Lederman HM. Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia. PLoS One. 2018; 13(12):e0209496. PMID: 30586396.
      View in: PubMed
    3. Buczynski BW, Mai N, Yee M, Allen JL, Prifti L, Cory-Slechta DA, Halterman MW, O'Reilly MA. Lung-Specific Extracellular Superoxide Dismutase Improves Cognition of Adult Mice Exposed to Neonatal Hyperoxia. Front Med (Lausanne). 2018; 5:334. PMID: 30619855.
      View in: PubMed
    4. Morris-Schaffer K, Sobolewski M, Welle K, Conrad K, Yee M, O'Reilly MA, Cory-Slechta DA. Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles. Neurotoxicol Teratol. 2018 Nov - Dec; 70:51-59. PMID: 30316930.
      View in: PubMed
    5. Brooks ED, Sun B, Feng L, Verma V, Zhao L, Gomez DR, Liao Z, Jeter M, O'Reilly M, Welsh JW, Nguyen QN, Erasmus JJ, Eapen G, Ahrar K, Antonoff MB, Hahn SM, Heymach JV, Rice DC, Chang JY. Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer. JAMA Netw Open. 2018 Aug 03; 1(4):e181390. PMID: 30646121.
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    6. Morris-Schaffer K, Sobolewski M, Allen JL, Marvin E, Yee M, Arora M, O'Reilly MA, Cory-Slechta DA. Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice. Neurotoxicology. 2018 07; 67:234-244. PMID: 29920326.
      View in: PubMed
    7. Yee M, Cohen ED, Domm W, Porter GA, McDavid AN, O'Reilly MA. Neonatal hyperoxia depletes pulmonary vein cardiomyocytes in adult mice via mitochondrial oxidation. Am J Physiol Lung Cell Mol Physiol. 2018 05 01; 314(5):L846-L859. PMID: 29345197.
      View in: PubMed
    8. Liao Z, Lee JJ, Komaki R, Gomez DR, O'Reilly MS, Fossella FV, Blumenschein GR, Heymach JV, Vaporciyan AA, Swisher SG, Allen PK, Choi NC, DeLaney TF, Hahn SM, Cox JD, Lu CS, Mohan R. Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer. J Clin Oncol. 2018 Jun 20; 36(18):1813-1822. PMID: 29293386.
      View in: PubMed
    9. Jeter MD, Gomez D, Nguyen QN, Komaki R, Zhang X, Zhu X, O'Reilly M, Fossella FV, Xu T, Wei X, Wang H, Yang W, Tsao A, Mohan R, Liao Z. Simultaneous Integrated Boost for Radiation Dose Escalation to the Gross Tumor Volume With Intensity Modulated (Photon) Radiation Therapy or Intensity Modulated Proton Therapy and Concurrent Chemotherapy for Stage II to III Non-Small Cell Lung Cancer: A Phase 1 Study. Int J Radiat Oncol Biol Phys. 2018 03 01; 100(3):730-737. PMID: 29248169.
      View in: PubMed
    10. Chang JY, Verma V, Li M, Zhang W, Komaki R, Lu C, Allen PK, Liao Z, Welsh J, Lin SH, Gomez D, Jeter M, O'Reilly M, Zhu RX, Zhang X, Li H, Mohan R, Heymach JV, Vaporciyan AA, Hahn S, Cox JD. Proton Beam Radiotherapy and Concurrent Chemotherapy for Unresectable Stage III Non-Small Cell Lung Cancer: Final Results of a Phase 2 Study. JAMA Oncol. 2017 Aug 10; 3(8):e172032. PMID: 28727865.
      View in: PubMed
    11. Domm W, Yee M, Misra RS, Gelein R, Nogales A, Martinez-Sobrido L, O'Reilly MA. Oxygen-dependent changes in lung development do not affect epithelial infection with influenza A virus. Am J Physiol Lung Cell Mol Physiol. 2017 Nov 01; 313(5):L940-L949. PMID: 28798254.
      View in: PubMed
    12. Resseguie EA, Brookes PS, O'Reilly MA. SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia. Exp Lung Res. 2017 Aug - Sep; 43(6-7):229-239. PMID: 28749708.
      View in: PubMed
    13. Tampourlou M, Ntali G, Ahmed S, Arlt W, Ayuk J, Byrne JV, Chavda S, Cudlip S, Gittoes N, Grossman A, Mitchell R, O'Reilly MW, Paluzzi A, Toogood A, Wass JAH, Karavitaki N. Outcome of Nonfunctioning Pituitary Adenomas That Regrow After Primary Treatment: A Study From Two Large UK Centers. J Clin Endocrinol Metab. 2017 06 01; 102(6):1889-1897. PMID: 28323946.
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    14. Yee M, Domm W, Gelein R, Bentley KL, Kottmann RM, Sime PJ, Lawrence BP, O'Reilly MA. Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells. Am J Respir Cell Mol Biol. 2017 04; 56(4):453-464. PMID: 27967234.
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    15. Sun B, Brooks ED, Komaki RU, Liao Z, Jeter MD, McAleer MF, Allen PK, Balter PA, Welsh JD, O'Reilly MS, Gomez D, Hahn SM, Roth JA, Mehran RJ, Heymach JV, Chang JY. 7-year follow-up after stereotactic ablative radiotherapy for patients with stage I non-small cell lung cancer: Results of a phase 2 clinical trial. Cancer. 2017 Aug 15; 123(16):3031-3039. PMID: 28346656.
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    16. Sun B, Brooks ED, Komaki R, Liao Z, Jeter M, McAleer M, Balter PA, Welsh JD, O'Reilly M, Gomez D, Hahn SM, Sepesi B, Rice DC, Heymach JV, Chang JY. Long-Term Outcomes of Salvage Stereotactic Ablative Radiotherapy for Isolated Lung Recurrence of Non-Small Cell Lung Cancer: A Phase II Clinical Trial. J Thorac Oncol. 2017 06; 12(6):983-992. PMID: 28259750.
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    17. O'Reilly MA. Giving New Identities to Alveolar Epithelial Type I Cells. Am J Respir Cell Mol Biol. 2017 03; 56(3):277-278. PMID: 28248135.
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    18. Chang JY, Zhang W, Komaki R, Choi NC, Chan S, Gomez D, O'Reilly M, Jeter M, Gillin M, Zhu X, Zhang X, Mohan R, Swisher S, Hahn S, Cox JD. Long-term outcome of phase I/II prospective study of dose-escalated proton therapy for early-stage non-small cell lung cancer. Radiother Oncol. 2017 02; 122(2):274-280. PMID: 28139305.
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    19. Brooks ED, Sun B, Zhao L, Komaki R, Liao Z, Jeter M, Welsh JW, O'Reilly MS, Gomez DR, Hahn SM, Heymach JV, Rice DC, Chang JY. Stereotactic Ablative Radiation Therapy is Highly Safe and Effective for Elderly Patients With Early-stage Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2017 07 15; 98(4):900-907. PMID: 28258887.
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    20. O'Reilly MW, Reulen RC, Gupta S, Thompson CA, Dineen R, Goulden EL, Bugg G, Pearce H, Toogood AA, Gittoes NJ, Mitchell R, Thompson CJ, Ayuk J. ACTH and gonadotropin deficiencies predict mortality in patients treated for nonfunctioning pituitary adenoma: long-term follow-up of 519 patients in two large European centres. Clin Endocrinol (Oxf). 2016 Nov; 85(5):748-756. PMID: 27327840.
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    21. Yee M, Gelein R, Mariani TJ, Lawrence BP, O'Reilly MA. The Oxygen Environment at Birth Specifies the Population of Alveolar Epithelial Stem Cells in the Adult Lung. Stem Cells. 2016 05; 34(5):1396-406. PMID: 26891117.
      View in: PubMed
    22. Wang XS, Shi Q, Williams LA, Komaki R, Gomez DR, Lin SH, Chang JY, O'Reilly MS, Bokhari RH, Cox JD, Mohan R, Cleeland CS, Liao Z. Prospective Study of Patient-Reported Symptom Burden in Patients With Non-Small-Cell Lung Cancer Undergoing Proton or Photon Chemoradiation Therapy. J Pain Symptom Manage. 2016 05; 51(5):832-8. PMID: 26891607.
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    23. Roca JB, de los Reyes VC, Racelis S, Deveraturda I, Sucaldito MN, Tayag E, O'Reilly M. Fireworks-related injury surveillance in the Philippines: trends in 2010-2014. Western Pac Surveill Response J. 2015 Oct-Dec; 6(4):1-6. PMID: 26798555.
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    24. Domm W, Misra RS, O'Reilly MA. Affect of Early Life Oxygen Exposure on Proper Lung Development and Response to Respiratory Viral Infections. Front Med (Lausanne). 2015; 2:55. PMID: 26322310.
      View in: PubMed
    25. Deveraturda I, Ventura RJ, de los Reyes VC, Sucaldito MN, O'Reilly M, Tayag E. Chelonitoxism outbreak: Sorsogon, Philippines, October 2014. Western Pac Surveill Response J. 2015 Apr-Jun; 6(2):90-1. PMID: 26306222.
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    26. Resseguie EA, Staversky RJ, Brookes PS, O'Reilly MA. Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction. Redox Biol. 2015 Aug; 5:176-185. PMID: 25967673.
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    27. Weber-Adrian D, Thévenot E, O'Reilly MA, Oakden W, Akens MK, Ellens N, Markham-Coultes K, Burgess A, Finkelstein J, Yee AJ, Whyne CM, Foust KD, Kaspar BK, Stanisz GJ, Chopra R, Hynynen K, Aubert I. Gene delivery to the spinal cord using MRI-guided focused ultrasound. Gene Ther. 2015 Jul; 22(7):568-77. PMID: 25781651.
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    28. Munir S, Chang JH, Salahudeen SR, Baranchuk A, Morris C, O'Reilly M, Pal RS. Atrial thrombi detection prior to pulmonary vein isolation: diagnostic accuracy of cardiac computed tomography versus transesophageal echocardiography. Cardiol J. 2015; 22(5):576-82. PMID: 25786766.
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    29. Hilgendorff A, O'Reilly MA. Bronchopulmonary dysplasia early changes leading to long-term consequences. Front Med (Lausanne). 2015; 2:2. PMID: 25729750.
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    30. Xu T, Liao Z, O'Reilly MS, Levy LB, Welsh JW, Wang LE, Lin SH, Komaki R, Liu Z, Wei Q, Gomez DR. Serum inflammatory miRNAs predict radiation esophagitis in patients receiving definitive radiochemotherapy for non-small cell lung cancer. Radiother Oncol. 2014 Dec; 113(3):379-84. PMID: 25466375.
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    31. Reilly EC, Martin KC, Jin GB, Yee M, O'Reilly MA, Lawrence BP. Neonatal hyperoxia leads to persistent alterations in NK responses to influenza A virus infection. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 01; 308(1):L76-85. PMID: 25381024.
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    32. Bhattacharya S, Zhou Z, Yee M, Chu CY, Lopez AM, Lunger VA, Solleti SK, Resseguie E, Buczynski B, Mariani TJ, O'Reilly MA. The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator. Am J Physiol Lung Cell Mol Physiol. 2014 Oct 01; 307(7):L516-23. PMID: 25150061.
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    33. Kalifa L, Gewandter JS, Staversky RJ, Sia EA, Brookes PS, O'Reilly MA. DNA double-strand breaks activate ATM independent of mitochondrial dysfunction in A549 cells. Free Radic Biol Med. 2014 Oct; 75:30-9. PMID: 25048973.
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    34. Maduekwe ET, Buczynski BW, Yee M, Rangasamy T, Stevens TP, Lawrence BP, O'Reilly MA. Cumulative neonatal oxygen exposure predicts response of adult mice infected with influenza A virus. Pediatr Pulmonol. 2015 Mar; 50(3):222-230. PMID: 24850805.
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    35. Yee M, Buczynski BW, O'Reilly MA. Neonatal hyperoxia stimulates the expansion of alveolar epithelial type II cells. Am J Respir Cell Mol Biol. 2014 Apr; 50(4):757-66. PMID: 24188066.
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    36. Regal JF, Lawrence BP, Johnson AC, Lojovich SJ, O'Reilly MA. Neonatal oxygen exposure alters airway hyper-responsiveness but not the response to allergen challenge in adult mice. Pediatr Allergy Immunol. 2014 Mar; 25(2):180-6. PMID: 24520985.
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    37. Gomez DR, Gladish GW, Wei X, Kotamarti KR, Allen PK, Cox JD, O'Reilly MS, Erasmus JJ, Fossella FV, Komaki R. Prognostic value of positron emission tomography/computed tomography findings in limited-stage small cell lung cancer before chemoradiation therapy. Am J Clin Oncol. 2014 Feb; 37(1):77-80. PMID: 23111360.
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    38. Wang H, Liao Z, Zhuang Y, Xu T, Nguyen QN, Levy LB, O'Reilly M, Gold KA, Gomez DR. Do angiotensin-converting enzyme inhibitors reduce the risk of symptomatic radiation pneumonitis in patients with non-small cell lung cancer after definitive radiation therapy? Analysis of a single-institution database. Int J Radiat Oncol Biol Phys. 2013 Dec 01; 87(5):1071-7. PMID: 24161424.
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    39. Perez-Nazario N, Rangel-Moreno J, O'Reilly MA, Pasparakis M, Gigliotti F, Wright TW. Selective ablation of lung epithelial IKK2 impairs pulmonary Th17 responses and delays the clearance of Pneumocystis. J Immunol. 2013 Nov 01; 191(9):4720-30. PMID: 24078701.
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    40. Shirvani SM, Juloori A, Allen PK, Komaki R, Liao Z, Gomez D, O'Reilly M, Welsh J, Papadimitrakopoulou V, Cox JD, Chang JY. Comparison of 2 common radiation therapy techniques for definitive treatment of small cell lung cancer. Int J Radiat Oncol Biol Phys. 2013 Sep 01; 87(1):139-47. PMID: 23920393.
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    41. Zhao L, Yee M, O'Reilly MA. Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-ß and BMP signaling. Am J Physiol Lung Cell Mol Physiol. 2013 Sep 15; 305(6):L409-18. PMID: 23831617.
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    42. Baird BN, Schliekelman MJ, Ahn YH, Chen Y, Roybal JD, Gill BJ, Mishra DK, Erez B, O'Reilly M, Yang Y, Patel M, Liu X, Thilaganathan N, Larina IV, Dickinson ME, West JL, Gibbons DL, Liu DD, Kim MP, Hicks JM, Wistuba II, Hanash SM, Kurie JM. Fibulin-2 is a driver of malignant progression in lung adenocarcinoma. PLoS One. 2013; 8(6):e67054. PMID: 23785517.
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    43. Buczynski BW, Yee M, Martin KC, Lawrence BP, O'Reilly MA. Neonatal hyperoxia alters the host response to influenza A virus infection in adult mice through multiple pathways. Am J Physiol Lung Cell Mol Physiol. 2013 Aug 15; 305(4):L282-90. PMID: 23748535.
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    44. Buczynski BW, Maduekwe ET, O'Reilly MA. The role of hyperoxia in the pathogenesis of experimental BPD. Semin Perinatol. 2013 Apr; 37(2):69-78. PMID: 23582960.
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    45. Isobe T, Onn A, Morgensztern D, Jacoby JJ, Wu W, Shintani T, Itasaka S, Shibuya K, Koo PJ, O'Reilly MS, Herbst RS. Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer. J Thorac Oncol. 2013 Feb; 8(2):140-6. PMID: 23328546.
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    46. Wang HM, Liao ZX, Komaki R, Welsh JW, O'Reilly MS, Chang JY, Zhuang Y, Levy LB, Lu C, Gomez DR. Improved survival outcomes with the incidental use of beta-blockers among patients with non-small-cell lung cancer treated with definitive radiation therapy. Ann Oncol. 2013 May; 24(5):1312-9. PMID: 23300016.
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    47. Yee M, Buczynski BW, Lawrence BP, O'Reilly MA. Neonatal hyperoxia increases sensitivity of adult mice to bleomycin-induced lung fibrosis. Am J Respir Cell Mol Biol. 2013 Feb; 48(2):258-66. PMID: 23258231.
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    48. Saintigny P, Massarelli E, Lin S, Ahn YH, Chen Y, Goswami S, Erez B, O'Reilly MS, Liu D, Lee JJ, Zhang L, Ping Y, Behrens C, Solis Soto LM, Heymach JV, Kim ES, Herbst RS, Lippman SM, Wistuba II, Hong WK, Kurie JM, Koo JS. CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma. Cancer Res. 2013 Jan 15; 73(2):571-82. PMID: 23204236.
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    49. Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh JW, O'Reilly MS, Hofstetter WL, Ajani JA, Komaki R, Cox JD, Sandulache VC, Myers JN, Guerrero TM. Metformin use and improved response to therapy in esophageal adenocarcinoma. Acta Oncol. 2013 Jun; 52(5):1002-9. PMID: 22950385.
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    50. O'Reilly MA. Angiotensin II: tapping the cell cycle machinery to kill endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 01; 303(7):L575-6. PMID: 22886501.
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    51. O'Reilly M. Considerations for evaluating the accuracy of hemoglobin monitoring. Anesthesiology. 2012 Aug; 117(2):429-30; author reply 430-1. PMID: 22828427.
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    52. Giannandrea M, Yee M, O'Reilly MA, Lawrence BP. Memory CD8+ T cells are sufficient to alleviate impaired host resistance to influenza A virus infection caused by neonatal oxygen supplementation. Clin Vaccine Immunol. 2012 Sep; 19(9):1432-41. PMID: 22787195.
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    53. O'Reilly MA, Yee M, Buczynski BW, Vitiello PF, Keng PC, Welle SL, Finkelstein JN, Dean DA, Lawrence BP. Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1. Am J Pathol. 2012 Aug; 181(2):441-51. PMID: 22677423.
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    54. Xu T, Wei Q, Lopez Guerra JL, Wang LE, Liu Z, Gomez D, O'Reilly M, Lin SH, Zhuang Y, Levy LB, Mohan R, Zhou H, Liao Z. HSPB1 gene polymorphisms predict risk of mortality for US patients after radio(chemo)therapy for non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2012 Oct 01; 84(2):e229-35. PMID: 22608953.
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    55. Buczynski BW, Yee M, Paige Lawrence B, O'Reilly MA. Lung development and the host response to influenza A virus are altered by different doses of neonatal oxygen in mice. Am J Physiol Lung Cell Mol Physiol. 2012 May 15; 302(10):L1078-87. PMID: 22408042.
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    56. Yin M, Liao Z, Yuan X, Guan X, O'Reilly MS, Welsh J, Wang LE, Wei Q. Polymorphisms of the vascular endothelial growth factor gene and severe radiation pneumonitis in non-small cell lung cancer patients treated with definitive radiotherapy. Cancer Sci. 2012 May; 103(5):945-50. PMID: 22320189.
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    57. Takahashi O, Komaki R, Smith PD, Jürgensmeier JM, Ryan A, Bekele BN, Wistuba II, Jacoby JJ, Korshunova MV, Biernacka A, Erez B, Hosho K, Herbst RS, O'Reilly MS. Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis. Clin Cancer Res. 2012 Mar 15; 18(6):1641-54. PMID: 22275507.
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    58. Komaki R, Wei X, Allen PK, Liao Z, Milas L, Cox JD, O'Reilly MS, Chang JY, McAleer MF, Jeter M, Blumenschein GR, Kies MS. Phase I study of celecoxib with concurrent irinotecan, Cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer. Front Oncol. 2011; 1:52. PMID: 22649768.
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    59. Gewandter JS, Bambara RA, O'Reilly MA. The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA. Cell Cycle. 2011 Aug 01; 10(15):2561-7. PMID: 21701263.
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    60. Yin M, Liao Z, Liu Z, Wang LE, O'Reilly M, Gomez D, Li M, Komaki R, Wei Q. Genetic variants of the nonhomologous end joining gene LIG4 and severe radiation pneumonitis in nonsmall cell lung cancer patients treated with definitive radiotherapy. Cancer. 2012 Jan 15; 118(2):528-35. PMID: 21717429.
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    61. Yee M, White RJ, Awad HA, Bates WA, McGrath-Morrow SA, O'Reilly MA. Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice. Am J Pathol. 2011 Jun; 178(6):2601-10. PMID: 21550015.
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    62. Ramachandran SK, Haider N, Saran KA, Mathis M, Kim J, Morris M, O'Reilly M. Life-threatening critical respiratory events: a retrospective study of postoperative patients found unresponsive during analgesic therapy. J Clin Anesth. 2011 May; 23(3):207-13. PMID: 21570616.
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    63. McGrath-Morrow SA, Lauer T, Collaco JM, Yee M, O'Reilly M, Mitzner W, Neptune E, Wise R, Biswal S. Neonatal hyperoxia contributes additively to cigarette smoke-induced chronic obstructive pulmonary disease changes in adult mice. Am J Respir Cell Mol Biol. 2011 Sep; 45(3):610-6. PMID: 21239606.
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    64. Wu YC, O'Reilly MA. Bcl-X(L) is the primary mediator of p21 protection against hyperoxia-induced cell death. Exp Lung Res. 2011 Mar; 37(2):82-91. PMID: 21128858.
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    65. Guan X, Yin M, Wei Q, Zhao H, Liu Z, Wang LE, Yuan X, O'Reilly MS, Komaki R, Liao Z. Genotypes and haplotypes of the VEGF gene and survival in locally advanced non-small cell lung cancer patients treated with chemoradiotherapy. BMC Cancer. 2010 Aug 16; 10:431. PMID: 20712888.
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    66. Chess PR, Benson RP, Maniscalco WM, Wright TW, O'Reilly MA, Johnston CJ. Murine mechanical ventilation stimulates alveolar epithelial cell proliferation. Exp Lung Res. 2010 Aug; 36(6):331-41. PMID: 20653468.
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    67. Zheng K, Haftel HM, Hirschl RB, O'Reilly M, Hanauer DA. Quantifying the impact of health IT implementations on clinical workflow: a new methodological perspective. J Am Med Inform Assoc. 2010 Jul-Aug; 17(4):454-61. PMID: 20595314.
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    68. Jacoby JJ, Erez B, Korshunova MV, Williams RR, Furutani K, Takahashi O, Kirkpatrick L, Lippman SM, Powis G, O'Reilly MS, Herbst RS. Treatment with HIF-1alpha antagonist PX-478 inhibits progression and spread of orthotopic human small cell lung cancer and lung adenocarcinoma in mice. J Thorac Oncol. 2010 Jul; 5(7):940-9. PMID: 20512076.
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    69. Staversky RJ, Vitiello PF, Yee M, Callahan LM, Dean DA, O'Reilly MA. Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development. Am J Respir Cell Mol Biol. 2010 Sep; 43(3):376-85. PMID: 19880821.
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    70. Doung-ngern P, Vatanaprasan T, Chungpaibulpatana J, Sitamanoch W, Netwong T, Sukhumkumpee S, O'Reilly M, Henderson A, Jiraphongsa C. Infections and treatment of wounds in survivors of the 2004 Tsunami in Thailand. Int Wound J. 2009 Oct; 6(5):347-54. PMID: 19912391.
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    71. Gewandter JS, Staversky RJ, O'Reilly MA. Hyperoxia augments ER-stress-induced cell death independent of BiP loss. Free Radic Biol Med. 2009 Dec 15; 47(12):1742-52. PMID: 19786088.
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    72. Yee M, Chess PR, McGrath-Morrow SA, Wang Z, Gelein R, Zhou R, Dean DA, Notter RH, O'Reilly MA. Neonatal oxygen adversely affects lung function in adult mice without altering surfactant composition or activity. Am J Physiol Lung Cell Mol Physiol. 2009 Oct; 297(4):L641-9. PMID: 19617311.
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    73. McGovern SL, Liao Z, Bucci MK, McAleer MF, Jeter MD, Chang JY, O'Reilly MS, Cox JD, Allen PK, Komaki R. Is sex associated with the outcome of patients treated with radiation for nonsmall cell lung cancer? Cancer. 2009 Jul 15; 115(14):3233-42. PMID: 19472405.
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    74. Lew BJ, Collins LL, O'Reilly MA, Lawrence BP. Activation of the aryl hydrocarbon receptor during different critical windows in pregnancy alters mammary epithelial cell proliferation and differentiation. Toxicol Sci. 2009 Sep; 111(1):151-62. PMID: 19502548.
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    75. Dejpichai R, Laosiritaworn Y, Phuthavathana P, Uyeki TM, O'Reilly M, Yampikulsakul N, Phurahong S, Poorak P, Prasertsopon J, Kularb R, Nateerom K, Sawanpanyalert N, Jiraphongsa C. Seroprevalence of antibodies to avian influenza virus A (H5N1) among residents of villages with human cases, Thailand, 2005. Emerg Infect Dis. 2009 May; 15(5):756-60. PMID: 19402962.
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    76. McGrath-Morrow S, Lauer T, Yee M, Neptune E, Podowski M, Thimmulappa RK, O'Reilly M, Biswal S. Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2009 Apr; 296(4):L565-73. PMID: 19151108.
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    77. Kheterpal S, O'Reilly M, Englesbe MJ, Rosenberg AL, Shanks AM, Zhang L, Rothman ED, Campbell DA, Tremper KK. Preoperative and intraoperative predictors of cardiac adverse events after general, vascular, and urological surgery. Anesthesiology. 2009 Jan; 110(1):58-66. PMID: 19104171.
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    78. Muravchick S, Caldwell JE, Epstein RH, Galati M, Levy WJ, O'Reilly M, Plagenhoef JS, Rehman M, Reich DL, Vigoda MM. Anesthesia information management system implementation: a practical guide. Anesth Analg. 2008 Nov; 107(5):1598-608. PMID: 18931218.
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    79. Campbell DA, Henderson WG, Englesbe MJ, Hall BL, O'Reilly M, Bratzler D, Dellinger EP, Neumayer L, Bass BL, Hutter MM, Schwartz J, Ko C, Itani K, Steinberg SM, Siperstein A, Sawyer RG, Turner DJ, Khuri SF. Surgical site infection prevention: the importance of operative duration and blood transfusion--results of the first American College of Surgeons-National Surgical Quality Improvement Program Best Practices Initiative. J Am Coll Surg. 2008 Dec; 207(6):810-20. PMID: 19183526.
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    80. Vitiello PF, Wu YC, Staversky RJ, O'Reilly MA. p21(Cip1) protects against oxidative stress by suppressing ER-dependent activation of mitochondrial death pathways. Free Radic Biol Med. 2009 Jan 01; 46(1):33-41. PMID: 18948188.
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    81. Pryhuber GS, Huyck HL, Bhagwat S, O'Reilly MA, Finkelstein JN, Gigliotti F, Wright TW. Parenchymal cell TNF receptors contribute to inflammatory cell recruitment and respiratory failure in Pneumocystis carinii-induced pneumonia. J Immunol. 2008 Jul 15; 181(2):1409-19. PMID: 18606695.
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    82. Gauger PG, Shanks A, Morris M, Greenfield ML, Burney RE, O'Reilly M. Propofol decreases early postoperative nausea and vomiting in patients undergoing thyroid and parathyroid operations. World J Surg. 2008 Jul; 32(7):1525-34. PMID: 18305999.
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    83. O'Reilly MS. The interaction of radiation therapy and antiangiogenic therapy. Cancer J. 2008 Jul-Aug; 14(4):207-13. PMID: 18677126.
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    84. Kheterpal S, Khodaparast O, Shanks A, O'Reilly M, Tremper KK. Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery. J Cardiothorac Vasc Anesth. 2008 Apr; 22(2):180-6. PMID: 18375317.
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    85. Gehen SC, Staversky RJ, Bambara RA, Keng PC, O'Reilly MA. hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress. Oncogene. 2008 Jul 03; 27(29):4065-74. PMID: 18332866.
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    86. O'Reilly MA, Marr SH, Yee M, McGrath-Morrow SA, Lawrence BP. Neonatal hyperoxia enhances the inflammatory response in adult mice infected with influenza A virus. Am J Respir Crit Care Med. 2008 May 15; 177(10):1103-10. PMID: 18292469.
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    87. Yao H, Yang SR, Edirisinghe I, Rajendrasozhan S, Caito S, Adenuga D, O'Reilly MA, Rahman I. Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice. Am J Respir Cell Mol Biol. 2008 Jul; 39(1):7-18. PMID: 18239191.
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    88. Kheterpal S, Tremper KK, Englesbe MJ, O'Reilly M, Shanks AM, Fetterman DM, Rosenberg AL, Swartz RD. Predictors of postoperative acute renal failure after noncardiac surgery in patients with previously normal renal function. Anesthesiology. 2007 Dec; 107(6):892-902. PMID: 18043057.
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    89. Zimmerman CR, Jackson A, Chaffee B, O'Reilly M. A dashboard model for monitoring alert effectiveness and bandwidth. AMIA Annu Symp Proc. 2007 Oct 11; 1176. PMID: 18694272.
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    90. Vitiello PF, Staversky RJ, Keng PC, O'Reilly MA. PUMA inactivation protects against oxidative stress through p21/Bcl-XL inhibition of bax death. Free Radic Biol Med. 2008 Feb 01; 44(3):367-74. PMID: 18215742.
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    91. Wu W, O'Reilly MS, Langley RR, Tsan RZ, Baker CH, Bekele N, Tang XM, Onn A, Fidler IJ, Herbst RS. Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice. Mol Cancer Ther. 2007 Oct; 6(10):2652-63. PMID: 17913856.
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    92. O'Reilly MS. Antiangiogenic antithrombin. Semin Thromb Hemost. 2007 Oct; 33(7):660-6. PMID: 18000792.
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    93. Shibuya K, Komaki R, Shintani T, Itasaka S, Ryan A, Jürgensmeier JM, Milas L, Ang K, Herbst RS, O'Reilly MS. Targeted therapy against VEGFR and EGFR with ZD6474 enhances the therapeutic efficacy of irradiation in an orthotopic model of human non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1534-43. PMID: 17889445.
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    94. Ammori JB, Sigakis M, Englesbe MJ, O'Reilly M, Pelletier SJ. Effect of intraoperative hyperglycemia during liver transplantation. J Surg Res. 2007 Jun 15; 140(2):227-33. PMID: 17509267.
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    95. Itasaka S, Komaki R, Herbst RS, Shibuya K, Shintani T, Hunter NR, Onn A, Bucana CD, Milas L, Ang KK, O'Reilly MS. Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice. Int J Radiat Oncol Biol Phys. 2007 Mar 01; 67(3):870-8. PMID: 17293237.
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    96. Kheterpal S, Gupta R, Blum JM, Tremper KK, O'Reilly M, Kazanjian PE. Electronic reminders improve procedure documentation compliance and professional fee reimbursement. Anesth Analg. 2007 Mar; 104(3):592-7. PMID: 17312215.
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    97. Wu W, Onn A, Isobe T, Itasaka S, Langley RR, Shitani T, Shibuya K, Komaki R, Ryan AJ, Fidler IJ, Herbst RS, O'Reilly MS. Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade. Mol Cancer Ther. 2007 Feb; 6(2):471-83. PMID: 17308046.
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    98. Herbst RS, Heymach JV, O'Reilly MS, Onn A, Ryan AJ. Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis. Expert Opin Investig Drugs. 2007 Feb; 16(2):239-49. PMID: 17243944.
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    99. O'Reilly MS. Antiangiogenesis and vascular endothelial growth factor/vascular endothelial growth factor receptor targeting as part of a combined-modality approach to the treatment of cancer. Int J Radiat Oncol Biol Phys. 2007; 69(2 Suppl):S64-6. PMID: 17848299.
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    100. Morrissey CO, Slavin MA, O'Reilly MA, Daffy JR, Seymour JF, Schwarer AP, Szer J. Caspofungin as salvage monotherapy for invasive aspergillosis in patients with haematological malignancies or following allogeneic stem cell transplantation: efficacy and concomitant cyclosporin A. Mycoses. 2007; 50 Suppl 1:24-37. PMID: 17394607.
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    101. Gehen SC, Vitiello PF, Bambara RA, Keng PC, O'Reilly MA. Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2007 Mar; 292(3):L716-24. PMID: 17085526.
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    102. Kheterpal S, Han R, Tremper KK, Shanks A, Tait AR, O'Reilly M, Ludwig TA. Incidence and predictors of difficult and impossible mask ventilation. Anesthesiology. 2006 Nov; 105(5):885-91. PMID: 17065880.
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    103. O'Reilly M, Talsma A, VanRiper S, Kheterpal S, Burney R. An anesthesia information system designed to provide physician-specific feedback improves timely administration of prophylactic antibiotics. Anesth Analg. 2006 Oct; 103(4):908-12. PMID: 17000802.
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    104. Bijli KM, Minhajuddin M, Fazal F, O'Reilly MA, Platanias LC, Rahman A. c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2007 Feb; 292(2):L396-404. PMID: 17012367.
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    105. Yee M, Vitiello PF, Roper JM, Staversky RJ, Wright TW, McGrath-Morrow SA, Maniscalco WM, Finkelstein JN, O'Reilly MA. Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development. Am J Physiol Lung Cell Mol Physiol. 2006 Nov; 291(5):L1101-11. PMID: 16861382.
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    106. Vitiello PF, Staversky RJ, Gehen SC, Johnston CJ, Finkelstein JN, Wright TW, O'Reilly MA. p21Cip1 protection against hyperoxia requires Bcl-XL and is uncoupled from its ability to suppress growth. Am J Pathol. 2006 Jun; 168(6):1838-47. PMID: 16723699.
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    107. Staversky RJ, Vitiello PF, Gehen SC, Helt CE, Rahman A, Keng PC, O'Reilly MA. p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L). Free Radic Biol Med. 2006 Aug 15; 41(4):601-9. PMID: 16863993.
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    108. Crane CH, Ellis LM, Abbruzzese JL, Amos C, Xiong HQ, Ho L, Evans DB, Tamm EP, Ng C, Pisters PW, Charnsangavej C, Delclos ME, O'Reilly M, Lee JE, Wolff RA. Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer. J Clin Oncol. 2006 Mar 01; 24(7):1145-51. PMID: 16505434.
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    109. O'Reilly MS. Radiation combined with antiangiogenic and antivascular agents. Semin Radiat Oncol. 2006 Jan; 16(1):45-50. PMID: 16378906.
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    110. Marcus K, Johnson M, Adam RM, O'Reilly MS, Donovan M, Atala A, Freeman MR, Soker S. Tumor cell-associated neuropilin-1 and vascular endothelial growth factor expression as determinants of tumor growth in neuroblastoma. Neuropathology. 2005 Sep; 25(3):178-87. PMID: 16193833.
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    111. Maniscalco WM, Watkins RH, Roper JM, Staversky R, O'Reilly MA. Hyperoxic ventilated premature baboons have increased p53, oxidant DNA damage and decreased VEGF expression. Pediatr Res. 2005 Sep; 58(3):549-56. PMID: 16148072.
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    112. Auten RL, O'Reilly MA, Oury TD, Nozik-Grayck E, Whorton MH. Transgenic extracellular superoxide dismutase protects postnatal alveolar epithelial proliferation and development during hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2006 Jan; 290(1):L32-40. PMID: 16100289.
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    113. Boo LM, Lin HH, Chung V, Zhou B, Louie SG, O'Reilly MA, Yen Y, Ann DK. High mobility group A2 potentiates genotoxic stress in part through the modulation of basal and DNA damage-dependent phosphatidylinositol 3-kinase-related protein kinase activation. Cancer Res. 2005 Aug 01; 65(15):6622-30. PMID: 16061642.
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    114. Pryhuber GS, Huyck HL, Roper JM, Cornejo J, O'Reilly MA, Pierce RH, Tsitsikov EN. Acute tumor necrosis factor-alpha-induced liver injury in the absence of tumor necrosis factor receptor-associated factor 1 gene expression. Am J Pathol. 2005 Jun; 166(6):1637-45. PMID: 15920149.
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    115. Greenfield ML, Rosenberg AL, O'Reilly M, Shanks AM, Sliwinski MJ, Nauss MD. The quality of randomized controlled trials in major anesthesiology journals. Anesth Analg. 2005 Jun; 100(6):1759-64. PMID: 15920210.
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    116. Chess PR, O'Reilly MA, Sachs F, Finkelstein JN. Reactive oxidant and p42/44 MAP kinase signaling is necessary for mechanical strain-induced proliferation in pulmonary epithelial cells. J Appl Physiol (1985). 2005 Sep; 99(3):1226-32. PMID: 15890751.
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    117. O'reilly MA, Vitiello PF, Gehen SC, Staversky RJ. p21(Cip1/WAF1/Sdi1) does not affect expression of base excision DNA repair enzymes during chronic oxidative stress. Antioxid Redox Signal. 2005 May-Jun; 7(5-6):719-25. PMID: 15890018.
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    118. Mazzatti DJ, Lee YJ, Helt CE, O'Reilly MA, Keng PC. p53 modulates radiation sensitivity independent of p21 transcriptional activation. Am J Clin Oncol. 2005 Feb; 28(1):43-50. PMID: 15685034.
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    119. Roper JM, Gehen SC, Staversky RJ, Hollander MC, Fornace AJ, O'Reilly MA. Loss of Gadd45a does not modify the pulmonary response to oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2005 Apr; 288(4):L663-71. PMID: 15653712.
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    120. O'Reilly MA. Redox activation of p21Cip1/WAF1/Sdi1: a multifunctional regulator of cell survival and death. Antioxid Redox Signal. 2005 Jan-Feb; 7(1-2):108-18. PMID: 15650400.
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    121. Onn A, Isobe T, Wu W, Itasaka S, Shintani T, Shibuya K, Kenji Y, O'reilly MS, Fidler IJ, Herbst RS. Epidermal growth factor receptor tyrosine kinase inhibitor does not improve paclitaxel effect in an orthotopic mouse model of lung cancer. Clin Cancer Res. 2004 Dec 15; 10(24):8613-9. PMID: 15623645.
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    122. Chess PR, O'Reilly MA, Toia L. Macroarray analysis reveals a strain-induced oxidant response in pulmonary epithelial cells. Exp Lung Res. 2004 Dec; 30(8):739-53. PMID: 15700550.
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    123. Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage. J Biol Chem. 2005 Jan 14; 280(2):1186-92. PMID: 15533933.
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    124. Raut CP, Takamori RK, Davis DW, Sweeney-Gotsch B, O'Reilly MS, McConkey DJ. Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer. Cancer Biol Ther. 2004 Jul; 3(7):679-87. PMID: 15197351.
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    125. Han R, Tremper KK, Kheterpal S, O'Reilly M. Grading scale for mask ventilation. Anesthesiology. 2004 Jul; 101(1):267. PMID: 15220820.
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    126. O'Reilly M, Sliwinski M, Shanks A, Greenfield ML, Gauger P. Patient satisfaction and outcome in thyroidectomy and parathyroidectomy in patients receiving propofol. J Clin Anesth. 2004 Mar; 16(2):139-40. PMID: 15110379.
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    127. McDonald DM, Teicher BA, Stetler-Stevenson W, Ng SS, Figg WD, Folkman J, Hanahan D, Auerbach R, O'Reilly M, Herbst R, Cheresh D, Gordon M, Eggermont A, Libutti SK. Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring. J Immunother. 2004 Mar-Apr; 27(2):161-75. PMID: 14770088.
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    128. Su C, Gao G, Schneider S, Helt C, Weiss C, O'Reilly MA, Bohmann D, Zhao J. DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway. EMBO J. 2004 Mar 10; 23(5):1133-43. PMID: 14976556.
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    129. Burney RE, Prabhu MA, Greenfield ML, Shanks A, O'Reilly M. Comparison of spinal vs general anesthesia via laryngeal mask airway in inguinal hernia repair. Arch Surg. 2004 Feb; 139(2):183-7. PMID: 14769578.
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    130. Roper JM, Mazzatti DJ, Watkins RH, Maniscalco WM, Keng PC, O'Reilly MA. In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2004 May; 286(5):L1045-54. PMID: 14729512.
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    131. McLean S, O'Reilly M, Doyle M, O Rathaille M. Improving Door-to-Drug time and ST segment resolution in AMI by moving thrombolysis administration to the Emergency Department. Accid Emerg Nurs. 2004 Jan; 12(1):2-9. PMID: 14700564.
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    132. Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O'Reilly MS, Hong WK, Fidler IJ, Putnam JB, Herbst RS. Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer. Clin Cancer Res. 2004 Jan 01; 10(1 Pt 1):136-43. PMID: 14734462.
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    133. Davis DW, Shen Y, Mullani NA, Wen S, Herbst RS, O'Reilly M, Abbruzzese JL, McConkey DJ. Quantitative analysis of biomarkers defines an optimal biological dose for recombinant human endostatin in primary human tumors. Clin Cancer Res. 2004 Jan 01; 10(1 Pt 1):33-42. PMID: 14734449.
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    134. Lee PJ, MacLennan A, Naughton NN, O'Reilly M. An analysis of reintubations from a quality assurance database of 152,000 cases. J Clin Anesth. 2003 Dec; 15(8):575-81. PMID: 14724078.
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    135. Onn A, Isobe T, Itasaka S, Wu W, O'Reilly MS, Ki Hong W, Fidler IJ, Herbst RS. Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice. Clin Cancer Res. 2003 Nov 15; 9(15):5532-9. PMID: 14654533.
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    136. Varughese R, Nayak JL, LoMonaco M, O'Reilly MA, Ryan RM, D'Angio CT. Effects of hyperoxia on tumor necrosis factor alpha and Grobeta expression in newborn rabbit lungs. Lung. 2003 Nov-Dec; 181(6):335-46. PMID: 14749938.
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    137. Helt CE, Staversky RJ, Lee YJ, Bambara RA, Keng PC, O'Reilly MA. The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2004 Mar; 286(3):L506-13. PMID: 12936910.
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    138. Herbst RS, O'Reilly MS. The rationale and potential of combining novel biologic therapies with radiotherapy: focus on non-small cell lung cancer. Semin Oncol. 2003 Aug; 30(4 Suppl 9):113-23. PMID: 12908142.
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    139. O'Reilly MA, Watkins RH, Staversky RJ, Maniscalco WM. Induced p21Cip1 in premature baboons with CLD: implications for alveolar hypoplasia. Am J Physiol Lung Cell Mol Physiol. 2003 Oct; 285(4):L964-71. PMID: 12871858.
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    140. Roper JM, Staversky RJ, Finkelstein JN, Keng PC, O'Reilly MA. Identification and isolation of mouse type II cells on the basis of intrinsic expression of enhanced green fluorescent protein. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L691-700. PMID: 12740214.
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    141. Camphausen K, Moses MA, Ménard C, Sproull M, Beecken WD, Folkman J, O'Reilly MS. Radiation abscopal antitumor effect is mediated through p53. Cancer Res. 2003 Apr 15; 63(8):1990-3. PMID: 12702593.
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    142. Greene AK, Wiener S, Puder M, Yoshida A, Shi B, Perez-Atayde AR, Efstathiou JA, Holmgren L, Adamis AP, Rupnick M, Folkman J, O'Reilly MS. Endothelial-directed hepatic regeneration after partial hepatectomy. Ann Surg. 2003 Apr; 237(4):530-5. PMID: 12677150.
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    143. Howlett JG, Johnstone DE, Sketris I, O'Reilly M, Horne GS, Cox JL. Identifying opportunities to address the congestive heart failure burden: the Improving Cardiovascular Outcomes in Nova Scotia (ICONS) study. Can J Cardiol. 2003 Mar 31; 19(4):439-44. PMID: 12704493.
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    144. Palmer T, Wahr JA, O'Reilly M, Greenfield ML. Reducing unnecessary cross-matching: a patient-specific blood ordering system is more accurate in predicting who will receive a blood transfusion than the maximum blood ordering system. Anesth Analg. 2003 Feb; 96(2):369-75, table of contents. PMID: 12538179.
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    145. O'Reilly MS. Therapeutic strategies using inhibitors of angiogenesis. Methods Mol Biol. 2003; 223:599-634. PMID: 12777753.
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    146. Moses MA, O'Reilly MS. Regulation of angiostatin mobilization by tumor-derived matrix metalloproteinase-2. Methods Mol Med. 2003; 74:375-90. PMID: 12415709.
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    147. O'Reilly MS. Vessel maneuvers: vaccine targets tumor vasculature. Nat Med. 2002 Dec; 8(12):1352-3. PMID: 12457172.
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    148. O'Reilly MS. Targeting multiple biological pathways as a strategy to improve the treatment of cancer. Clin Cancer Res. 2002 Nov; 8(11):3309-10. PMID: 12429615.
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    149. Maniscalco WM, Watkins RH, O'Reilly MA, Shea CP. Increased epithelial cell proliferation in very premature baboons with chronic lung disease. Am J Physiol Lung Cell Mol Physiol. 2002 Nov; 283(5):L991-L1001. PMID: 12376352.
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    150. O'Reilly MA, Staversky RJ, Finkelstein JN, Keng PC. Activation of the G2 cell cycle checkpoint enhances survival of epithelial cells exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2003 Feb; 284(2):L368-75. PMID: 12388347.
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    151. Schwartz GJ, Kittelberger AM, Watkins RH, O'Reilly MA. Carbonic anhydrase XII mRNA encodes a hydratase that is differentially expressed along the rabbit nephron. Am J Physiol Renal Physiol. 2003 Feb; 284(2):F399-410. PMID: 12388401.
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    152. Rancourt RC, Hayes DD, Chess PR, Keng PC, O'Reilly MA. Growth arrest in G1 protects against oxygen-induced DNA damage and cell death. J Cell Physiol. 2002 Oct; 193(1):26-36. PMID: 12209877.
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    153. Staversky RJ, Watkins RH, Wright TW, Hernady E, LoMonaco MB, D'Angio CT, Williams JP, Maniscalco WM, O'Reilly MA. Normal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1). Am J Pathol. 2002 Oct; 161(4):1383-93. PMID: 12368211.
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    154. Herbst RS, Hess KR, Tran HT, Tseng JE, Mullani NA, Charnsangavej C, Madden T, Davis DW, McConkey DJ, O'Reilly MS, Ellis LM, Pluda J, Hong WK, Abbruzzese JL. Phase I study of recombinant human endostatin in patients with advanced solid tumors. J Clin Oncol. 2002 Sep 15; 20(18):3792-803. PMID: 12228199.
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    155. Herbst RS, Mullani NA, Davis DW, Hess KR, McConkey DJ, Charnsangavej C, O'Reilly MS, Kim HW, Baker C, Roach J, Ellis LM, Rashid A, Pluda J, Bucana C, Madden TL, Tran HT, Abbruzzese JL. Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin. J Clin Oncol. 2002 Sep 15; 20(18):3804-14. PMID: 12228200.
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    156. Ambati BK, Joussen AM, Ambati J, Moromizato Y, Guha C, Javaherian K, Gillies S, O'Reilly MS, Adamis AP. Angiostatin inhibits and regresses corneal neovascularization. Arch Ophthalmol. 2002 Aug; 120(8):1063-8. PMID: 12149060.
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    157. O'Reilly MS. The combination of antiangiogenic therapy with other modalities. Cancer J. 2002 May-Jun; 8 Suppl 1:S89-99. PMID: 12075706.
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    158. Kisker O, Onizuka S, Banyard J, Komiyama T, Becker CM, Achilles EG, Barnes CM, O'Reilly MS, Folkman J, Pirie-Shepherd SR. Generation of multiple angiogenesis inhibitors by human pancreatic cancer. Cancer Res. 2001 Oct 01; 61(19):7298-304. PMID: 11585769.
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    159. Helt CE, Rancourt RC, Staversky RJ, O'Reilly MA. p53-dependent induction of p21(Cip1/WAF1/Sdi1) protects against oxygen-induced toxicity. Toxicol Sci. 2001 Oct; 63(2):214-22. PMID: 11568365.
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    160. O'Reilly MA. DNA damage and cell cycle checkpoints in hyperoxic lung injury: braking to facilitate repair. Am J Physiol Lung Cell Mol Physiol. 2001 Aug; 281(2):L291-305. PMID: 11435201.
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    161. Lewis VO, O'Reilly MS, Gehrmann M, Llinás M, Schaller J, Weissbach L. Inhibition of tumor growth by plasminogen-related protein-B. Anticancer Res. 2001 Jul-Aug; 21(4A):2287-91. PMID: 11724284.
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    162. O'Reilly MA, Staversky RJ, Watkins RH, Reed CK, de Mesy Jensen KL, Finkelstein JN, Keng PC. The cyclin-dependent kinase inhibitor p21 protects the lung from oxidative stress. Am J Respir Cell Mol Biol. 2001 Jun; 24(6):703-10. PMID: 11415935.
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    163. Rancourt RC, Keng PC, Helt CE, O'Reilly MA. The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2001 Apr; 280(4):L617-26. PMID: 11238001.
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    164. Camphausen K, Moses MA, Beecken WD, Khan MK, Folkman J, O'Reilly MS. Radiation therapy to a primary tumor accelerates metastatic growth in mice. Cancer Res. 2001 Mar 01; 61(5):2207-11. PMID: 11280788.
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    165. O'Reilly MA, Staversky RJ, Huyck HL, Watkins RH, LoMonaco MB, D'Angio CT, Baggs RB, Maniscalco WM, Pryhuber GS. Bcl-2 family gene expression during severe hyperoxia induced lung injury. Lab Invest. 2000 Dec; 80(12):1845-54. PMID: 11140697.
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    166. Johnston CJ, Driscoll KE, Finkelstein JN, Baggs R, O'Reilly MA, Carter J, Gelein R, Oberdörster G. Pulmonary chemokine and mutagenic responses in rats after subchronic inhalation of amorphous and crystalline silica. Toxicol Sci. 2000 Aug; 56(2):405-13. PMID: 10911000.
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    167. Browder T, Butterfield CE, Kräling BM, Shi B, Marshall B, O'Reilly MS, Folkman J. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res. 2000 Apr 01; 60(7):1878-86. PMID: 10766175.
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    168. O'Reilly MA, Staversky RJ, Watkins RH, Maniscalco WM, Keng PC. p53-independent induction of GADD45 and GADD153 in mouse lungs exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2000 Mar; 278(3):L552-9. PMID: 10710528.
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    169. Pryhuber GS, Huyck HL, Staversky RJ, Finkelstein JN, O'Reilly MA. Tumor necrosis factor-alpha-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2. Am J Respir Cell Mol Biol. 2000 Feb; 22(2):150-6. PMID: 10657935.
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    170. Rancourt RC, Staversky RJ, Keng PC, O'Reilly MA. Hyperoxia inhibits proliferation of Mv1Lu epithelial cells independent of TGF-beta signaling. Am J Physiol. 1999 12; 277(6):L1172-8. PMID: 10600888.
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    171. O'Reilly MS, Wiederschain D, Stetler-Stevenson WG, Folkman J, Moses MA. Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance. J Biol Chem. 1999 Oct 08; 274(41):29568-71. PMID: 10506224.
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    172. O'Reilly MS, Pirie-Shepherd S, Lane WS, Folkman J. Antiangiogenic activity of the cleaved conformation of the serpin antithrombin. Science. 1999 Sep 17; 285(5435):1926-8. PMID: 10489375.
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    173. Paull AE, O'Reilly MA, Stanley PA. Disseminated tuberculosis: still a diagnostic challenge. Med J Aust. 1999 May 17; 170(10):482-5. PMID: 10376025.
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    174. Sim BK, Fogler WE, Zhou XH, Liang H, Madsen JW, Luu K, O'Reilly MS, Tomaszewski JE, Fortier AH. Zinc ligand-disrupted recombinant human Endostatin: potent inhibition of tumor growth, safety and pharmacokinetic profile. Angiogenesis. 1999; 3(1):41-51. PMID: 14517443.
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    175. Boehm T, O'reilly MS, Keough K, Shiloach J, Shapiro R, Folkman J. Zinc-binding of endostatin is essential for its antiangiogenic activity. Biochem Biophys Res Commun. 1998 Nov 09; 252(1):190-4. PMID: 9813168.
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    176. O'Reilly MA, Staversky RJ, Watkins RH, Maniscalco WM. Accumulation of p21(Cip1/WAF1) during hyperoxic lung injury in mice. Am J Respir Cell Mol Biol. 1998 Nov; 19(5):777-85. PMID: 9806742.
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    177. Casey ES, O'Reilly MA, Conlon FL, Smith JC. The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element. Development. 1998 Oct; 125(19):3887-94. PMID: 9729496.
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    178. Claesson-Welsh L, Welsh M, Ito N, Anand-Apte B, Soker S, Zetter B, O'Reilly M, Folkman J. Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD. Proc Natl Acad Sci U S A. 1998 May 12; 95(10):5579-83. PMID: 9576925.
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    179. Cao Y, O'Reilly MS, Marshall B, Flynn E, Ji RW, Folkman J. Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases. J Clin Invest. 1998 Mar 01; 101(5):1055-63. PMID: 9486976.
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    180. O'Reilly MA, Staversky RJ, Stripp BR, Finkelstein JN. Exposure to hyperoxia induces p53 expression in mouse lung epithelium. Am J Respir Cell Mol Biol. 1998 Jan; 18(1):43-50. PMID: 9448044.
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    181. Boehm T, Folkman J, Browder T, O'Reilly MS. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature. 1997 Nov 27; 390(6658):404-7. PMID: 9389480.
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    182. O'Reilly MA, Stripp BR, Pryhuber GS. Epithelial-mesenchymal interactions in the alteration of gene expression and morphology following lung injury. Microsc Res Tech. 1997 Sep 01; 38(5):473-9. PMID: 9376650.
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    183. Wu Z, O'Reilly MS, Folkman J, Shing Y. Suppression of tumor growth with recombinant murine angiostatin. Biochem Biophys Res Commun. 1997 Jul 30; 236(3):651-4. PMID: 9245707.
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    184. Tada M, O'Reilly MA, Smith JC. Analysis of competence and of Brachyury autoinduction by use of hormone-inducible Xbra. Development. 1997 Jun; 124(11):2225-34. PMID: 9187148.
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    185. Sim BK, O'Reilly MS, Liang H, Fortier AH, He W, Madsen JW, Lapcevich R, Nacy CA. A recombinant human angiostatin protein inhibits experimental primary and metastatic cancer. Cancer Res. 1997 Apr 01; 57(7):1329-34. PMID: 9102221.
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    186. O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E, Birkhead JR, Olsen BR, Folkman J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell. 1997 Jan 24; 88(2):277-85. PMID: 9008168.
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    187. O'Reilly MS. Angiostatin: an endogenous inhibitor of angiogenesis and of tumor growth. EXS. 1997; 79:273-94. PMID: 9002223.
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    188. O'Reilly MS. The preclinical evaluation of angiogenesis inhibitors. Invest New Drugs. 1997; 15(1):5-13. PMID: 9195285.
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    189. O'Reilly MA, Staversky RJ, Flanders KC, Johnston CJ, Finkelstein JN. Temporal changes in expression of TGF-beta isoforms in mouse lung exposed to oxygen. Am J Physiol. 1997 Jan; 272(1 Pt 1):L60-7. PMID: 9038903.
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    190. Cao Y, Ji RW, Davidson D, Schaller J, Marti D, Söhndel S, McCance SG, O'Reilly MS, Llinás M, Folkman J. Kringle domains of human angiostatin. Characterization of the anti-proliferative activity on endothelial cells. J Biol Chem. 1996 Nov 15; 271(46):29461-7. PMID: 8910613.
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    191. O'Reilly MS, Holmgren L, Chen C, Folkman J. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat Med. 1996 Jun; 2(6):689-92. PMID: 8640562.
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    192. O'Reilly MA, Heron CW, Glees JP, O'Reilly PM. A painful shoulder. Mil Med. 1996 May; 161(5):306-7. PMID: 8855066.
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    193. Parangi S, O'Reilly M, Christofori G, Holmgren L, Grosfeld J, Folkman J, Hanahan D. Antiangiogenic therapy of transgenic mice impairs de novo tumor growth. Proc Natl Acad Sci U S A. 1996 Mar 05; 93(5):2002-7. PMID: 8700875.
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    194. O'Reilly MA, O'Reilly PM, Glees J. The radiological features of primary small-cell carcinoma of the esophagus. Dysphagia. 1996; 11(3):191-3. PMID: 8755464.
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    195. O'Reilly MA, Smith JC, Cunliffe V. Patterning of the mesoderm in Xenopus: dose-dependent and synergistic effects of Brachyury and Pintallavis. Development. 1995 May; 121(5):1351-9. PMID: 7789266.
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    196. Voest EE, Kenyon BM, O'Reilly MS, Truitt G, D'Amato RJ, Folkman J. Inhibition of angiogenesis in vivo by interleukin 12. J Natl Cancer Inst. 1995 Apr 19; 87(8):581-6. PMID: 7538593.
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    197. O'Reilly MS, Brem H, Folkman J. Treatment of murine hemangioendotheliomas with the angiogenesis inhibitor AGM-1470. J Pediatr Surg. 1995 Feb; 30(2):325-9; discussion 329-30. PMID: 7738759.
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    198. Holmgren L, O'Reilly MS, Folkman J. Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat Med. 1995 Feb; 1(2):149-53. PMID: 7585012.
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    199. O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell. 1994 Oct 21; 79(2):315-28. PMID: 7525077.
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    200. Miller JW, Adamis AP, Shima DT, D'Amore PA, Moulton RS, O'Reilly MS, Folkman J, Dvorak HF, Brown LF, Berse B, et al. Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am J Pathol. 1994 Sep; 145(3):574-84. PMID: 7521577.
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    201. O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Cao Y, Moses M, Lane WS, Sage EH, Folkman J. Angiostatin: a circulating endothelial cell inhibitor that suppresses angiogenesis and tumor growth. Cold Spring Harb Symp Quant Biol. 1994; 59:471-82. PMID: 7587101.
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    202. Geiser AG, Busam KJ, Kim SJ, Lafyatis R, O'Reilly MA, Webbink R, Roberts AB, Sporn MB. Regulation of the transforming growth factor-beta 1 and -beta 3 promoters by transcription factor Sp1. Gene. 1993 Jul 30; 129(2):223-8. PMID: 8325508.
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    203. O'Reilly MA, Geiser AG, Kim SJ, Bruggeman LA, Luu AX, Roberts AB, Sporn MB. Identification of an activating transcription factor (ATF) binding site in the human transforming growth factor-beta 2 promoter. J Biol Chem. 1992 Oct 05; 267(28):19938-43. PMID: 1400310.
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    204. Kelly D, O'Reilly MA, Rizzino A. Differential regulation of the transforming growth factor type-beta 2 gene promoter in embryonal carcinoma cells and their differentiated cells. Dev Biol. 1992 Sep; 153(1):172-5. PMID: 1516748.
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    205. Kim SJ, Wagner S, Liu F, O'Reilly MA, Robbins PD, Green MR. Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription factor ATF-2. Nature. 1992 Jul 23; 358(6384):331-4. PMID: 1641004.
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    206. Bang YJ, Kim SJ, Danielpour D, O'Reilly MA, Kim KY, Myers CE, Trepel JB. Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3556-60. PMID: 1373503.
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    207. Whitsett JA, Budden A, Hull WM, Clark JC, O'Reilly MA. Transforming growth factor-beta inhibits surfactant protein A expression in vitro. Biochim Biophys Acta. 1992 Feb 12; 1123(3):257-62. PMID: 1536863.
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    208. O'Reilly MA, Danielpour D, Roberts AB, Sporn MB. Regulation of expression of transforming growth factor-beta 2 by transforming growth factor-beta isoforms is dependent upon cell type. Growth Factors. 1992; 6(3):193-201. PMID: 1389225.
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    209. O'Reilly MA, Clark JC, Whitsett JA. Glucocorticoid enhances pulmonary surfactant protein B gene transcription. Am J Physiol. 1991 Feb; 260(2 Pt 1):L37-43. PMID: 1996661.
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    210. Noma T, Glick AB, Geiser AG, O'Reilly MA, Miller J, Roberts AB, Sporn MB. Molecular cloning and structure of the human transforming growth factor-beta 2 gene promoter. Growth Factors. 1991; 4(4):247-55. PMID: 1764261.
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    211. Roberts AB, Kim SJ, Noma T, Glick AB, Lafyatis R, Lechleider R, Jakowlew SB, Geiser A, O'Reilly MA, Danielpour D, et al. Multiple forms of TGF-beta: distinct promoters and differential expression. Ciba Found Symp. 1991; 157:7-15; discussion 15-28. PMID: 1906395.
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    212. Pryhuber GS, O'Reilly MA, Clark JC, Hull WM, Fink I, Whitsett JA. Phorbol ester inhibits surfactant protein SP-A and SP-B expression. J Biol Chem. 1990 Dec 05; 265(34):20822-8. PMID: 2249989.
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    213. O'Reilly MA, Gazdar AF, Clark JC, Pilot-Matias TJ, Wert SE, Hull WM, Whitsett JA. Glucocorticoids regulate surfactant protein synthesis in a pulmonary adenocarcinoma cell line. Am J Physiol. 1989 Dec; 257(6 Pt 1):L385-92. PMID: 2610267.
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    214. O'Reilly MA, Weaver TE, Pilot-Matias TJ, Sarin VK, Gazdar AF, Whitsett JA. In vitro translation, post-translational processing and secretion of pulmonary surfactant protein B precursors. Biochim Biophys Acta. 1989 May 10; 1011(2-3):140-8. PMID: 2713400.
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    215. O'Reilly MA, Gazdar AF, Morris RE, Whitsett JA. Differential effects of glucocorticoid on expression of surfactant proteins in a human lung adenocarcinoma cell line. Biochim Biophys Acta. 1988 Jun 30; 970(2):194-204. PMID: 3382698.
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    216. O'Reilly MA, Nogee L, Whitsett JA. Requirement of the collagenous domain for carbohydrate processing and secretion of a surfactant protein, SP-A. Biochim Biophys Acta. 1988 Apr 25; 969(2):176-84. PMID: 3355864.
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    217. Preclinical and clinical studies of recombinant human endostatin. European Journal of Cancer. 37.
    218. Erratum. Journal of Clinical Investigation. 102:2028.
    219. Phase I study of celecoxib with concurrent irinotecan, cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer. Frontiers in Oncology. 1.
    220. Prospective Study of Patient-Reported Symptom Burden in Patients With Non-Small-Cell Lung Cancer Undergoing Proton or Photon Chemoradiation Therapy. Journal of Pain and Symptom Management.
    221. Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer (Cancer Biology and Therapy (2004) 3, 7, (679-87). Cancer Biology and Therapy. 8:984.
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