TitleAssociate Professor
InstitutionMD Anderson
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    1. El Hussein S, Medeiros LJ, Gruschkus SK, Wei P, Schlette E, Fang H, Jelloul FZ, Wang W, Fiskus W, Kanagal-Shamanna R, Loghavi S, Yang H, Li S, Xu J, Tang Z, Thakral B, Jain N, Wierda WG, Patel K, Bhalla KN, Khoury JD. Immune evasion phenotype is common in Richter transformation diffuse large B-cell lymphoma?variant. Virchows Arch. 2023 Jun; 482(6):1011-1019. PMID: 36864257.
      Citations:    Fields:    Translation:HumansCells
    2. El Hussein S, Medeiros LJ, Lyapichev KA, Fang H, Jelloul FZ, Fiskus W, Chen J, Wei P, Schlette E, Xu J, Li S, Kanagal-Shamanna R, Yang H, Tang Z, Thakral B, Loghavi S, Jain N, Thompson PA, Ferrajoli A, Wierda WG, Jabbour E, Patel KP, Dabaja BS, Bhalla KN, Khoury JD. Immunophenotypic and genomic landscape of Richter transformation diffuse large B-cell lymphoma. Pathology. 2023 Jun; 55(4):514-524. PMID: 36933995.
      Citations:    Fields:    Translation:Humans
    3. Fang H, Wang SA, You MJ, Hu S, Miranda RN, Tang Z, Lin P, Jorgensen JL, Xu J, Thakral B, Schlette EJ, El Hussein S, Bueso-Ramos C, Medeiros LJ, Wang W. Flow cytometry immunophenotypic features of pure erythroid leukemia and the distinction from reactive erythroid precursors. Cytometry B Clin Cytom. 2022 11; 102(6):440-447. PMID: 36156384.
      Citations:    Fields:    Translation:Humans
    4. Iqbal F, Joya Sosa Y, Kramer-Smotherman DN, Posleman Monetto FE, Dong J, He J, Musunuru T, Schlette EJ, Lyapichev KA. Breast T-Lymphoblastic Lymphoma Presenting as a Single Mass in a Young Female with Family History of Breast Cancer. Int J Surg Pathol. 2022 Oct; 30(7):760-768. PMID: 35188824.
      Citations:    Fields:    
    5. Marques-Piubelli ML, Schlette EJ, Khoury JD, Furqan F, Vega F, Soto LMS, Wistuba II, Wierda WG, Konopleva M, Ferrajoli A, Strati P. Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax. Leuk Lymphoma. 2021 05; 62(5):1129-1135. PMID: 33327833.
      Citations: 3     Fields:    Translation:Humans
    6. Strati P, Schlette EJ, Solis Soto LM, Duenas DE, Sivina M, Kim E, Keating MJ, Wierda WG, Ferrajoli A, Kantarjian H, Estrov Z, Jain N, Thompson PA, Wistuba II, Burger JA. Achieving complete remission in CLL patients treated with ibrutinib: clinical significance and predictive factors. Blood. 2020 02 13; 135(7):510-513. PMID: 31895947; PMCID: PMC7019190.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    7. Xu J, Liu JL, Medeiros LJ, Huang W, Khoury JD, McDonnell TJ, Tang G, Schlette E, Yin CC, Bueso-Ramos CE, Lin P, Li S. MYC rearrangement and MYC/BCL2 double expression but not cell-of-origin predict prognosis in R-CHOP?treated diffuse large B-cell lymphoma. Eur J Haematol. 2020 Apr; 104(4):336-343. PMID: 31944390.
      Citations: 4     Fields:    Translation:Humans
    8. Lyapichev KA, Medeiros LJ, Evans MG, Liu H, Miranda AR, Hunt KK, Clemens MW, Stewart JM, Amin MB, Quesada AE, Chai SM, Di Napoli A, Yoga A, Dave SK, Wistuba II, Wu Y, Bueso-Ramos CE, Schlette EJ, Ferrufino-Schmidt MC, Loghavi S, Khoury JD, Young KH, Miranda RN, Pi?a-Oviedo S. A proposal for pathologic processing of breast implant capsules in patients with suspected breast implant anaplastic large cell lymphoma. Mod Pathol. 2020 03; 33(3):367-379. PMID: 31383966; PMCID: PMC7489290.
      Citations: 6     Fields:    Translation:Humans
    9. Garces S, Khoury JD, Kanagal-Shamanna R, Salem A, Wang SA, Ok CY, Hu S, Patel KP, Routbort MJ, Luthra R, Tang G, Schlette EJ, Bueso-Ramos CE, Medeiros LJ, Loghavi S. Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype, and TP53 disruption. Hum Pathol. 2018 12; 82:215-231. PMID: 30086334.
      Citations: 3     Fields:    Translation:HumansCells
    10. Liu H, Wang SA, Schlette EJ, Xu J, Jorgensen JL, Cameron Yin C, Li S, Jeffrey Medeiros L, Tang G. Myeloid neoplasms with t(16;21)(q24;q22)/RUNX1-RUNX1T3 mimics acute myeloid leukemia with RUNX1-RUNX1T1. Ann Hematol. 2018 Oct; 97(10):1775-1783. PMID: 29872884.
      Citations: 2     Fields:    Translation:HumansCells
    11. Kurt H, Medeiros LJ, Khoury JD, Schlette EJ. Epstein-Barr virus-positive follicular lymphoma. Br J Haematol. 2018 09; 182(6):757. PMID: 29808924.
      Citations: 1     Fields:    Translation:HumansCells
    12. Hu Z, Sun Y, Schlette EJ, Tang G, Li S, Xu J, Yin CC, Young KH, Patel KP, Miranda RN, Goswami M, Wang M, Jorgensen JL, Medeiros LJ, Wang SA. CD200 expression in mantle cell lymphoma identifies a unique subgroup of patients with frequent IGHV mutations, absence of SOX11 expression, and an indolent clinical course. Mod Pathol. 2018 02; 31(2):327-336. PMID: 28984300.
      Citations: 9     Fields:    Translation:Humans
    13. Boddu P, Schlette E, Thakral B, Tang G, Pemmaraju N, Kadia T, Ferrajoli A, Ravandi F, Wierda W, Jain N. Acute promyelocytic leukemia in a patient with chronic lymphocytic leukemia-A case report. Hematol Oncol Stem Cell Ther. 2019 Sep; 12(3):161-165. PMID: 28830803.
      Citations:    Fields:    Translation:Humans
    14. Hidalgo Lopez JE, Yabe M, Carballo-Zarate AA, Wang SA, Jorgensen JL, Ahmed S, Lee J, Li S, Schlette E, McDonnell T, Miranda RN, Medeiros LJ, Bueso-Ramos CE, Yin CC. Donor-Derived T-Cell Large Granular Lymphocytic Leukemia in a Patient With Peripheral T-Cell Lymphoma. J Natl Compr Canc Netw. 2016 08; 14(8):939-44. PMID: 27496109.
      Citations: 4     Fields:    Translation:HumansCells
    15. Cheah CY, Dsouza L, Taggart MW, Schlette EJ, Turturro F. Diffuse large B-cell lymphoma with microsatellite instability developing in the setting of Muir-Torre variant hereditary non-polyposis colon cancer. J Clin Pathol. 2015 Sep; 68(9):755-7. PMID: 26008772.
      Citations: 3     Fields:    Translation:Humans
    16. Falchi L, Keating MJ, Marom EM, Truong MT, Schlette EJ, Sargent RL, Trinh L, Wang X, Smith SC, Jain N, Estrov Z, O'Brien S, Wierda WG, Lerner S, Ferrajoli A. Correlation between FDG/PET, histology, characteristics, and survival in 332 patients with chronic lymphoid leukemia. Blood. 2014 May 01; 123(18):2783-90. PMID: 24615780; PMCID: PMC4123418.
      Citations: 38     Fields:    Translation:Humans
    17. Leventaki V, Drakos E, Karanikou M, Psatha K, Lin P, Schlette E, Eliopoulos A, Vassilakopoulos TP, Papadaki H, Patsouris E, Medeiros LJ, Rassidakis GZ. c-JUN N-terminal kinase (JNK) is activated and contributes to tumor cell proliferation in classical Hodgkin lymphoma. Hum Pathol. 2014 Mar; 45(3):565-72. PMID: 24457077.
      Citations: 12     Fields:    Translation:HumansCells
    18. Jain P, Benjamini O, Schlette E, Thomas DA, O'Brien S. Late extramedullary recurrence of adult onset Burkitt's lymphoma mimicking peritoneal carcinomatosis. Am J Hematol. 2013 Oct; 88(10):920-1. PMID: 23674399.
      Citations:    Fields:    Translation:Humans
    19. Munoz J, Schlette E, Kurzrock R. Rapid response to vemurafenib in a heavily pretreated patient with hairy cell leukemia and a BRAF mutation. J Clin Oncol. 2013 Jul 10; 31(20):e351-2. PMID: 23733763.
      Citations: 27     Fields:    Translation:Humans
    20. Benjamini O, Jain P, Schlette E, Sciffman JS, Estrov Z, Keating M. Chronic lymphocytic leukemia with central nervous system involvement: a high-risk disease? Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):338-41. PMID: 23332395; PMCID: PMC4167026.
      Citations: 8     Fields:    Translation:Humans
    21. Wierda WG, O'Brien S, Wang X, Faderl S, Ferrajoli A, Do KA, Garcia-Manero G, Cortes J, Thomas D, Koller CA, Burger JA, Lerner S, Schlette E, Abruzzo L, Kantarjian HM, Keating MJ. Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia. J Clin Oncol. 2011 Nov 01; 29(31):4088-95. PMID: 21969505; PMCID: PMC4876352.
      Citations: 43     Fields:    Translation:Humans
    22. Vishwamitra D, Shi P, Wilson D, Manshouri R, Vega F, Schlette EJ, Amin HM. Expression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma. Haematologica. 2011 Jun; 96(6):871-80. PMID: 21330319; PMCID: PMC3105649.
      Citations: 15     Fields:    Translation:HumansCells
    23. Drakos E, Leventaki V, Atsaves V, Schlette EJ, Lin P, Vega F, Miranda RN, Claret FX, Medeiros LJ, Rassidakis GZ. Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas. Hum Pathol. 2011 Aug; 42(8):1117-24. PMID: 21315423; PMCID: PMC4089890.
      Citations: 8     Fields:    Translation:HumansCells
    24. Chen W, Drakos E, Grammatikakis I, Schlette EJ, Li J, Leventaki V, Staikou-Drakopoulou E, Patsouris E, Panayiotidis P, Medeiros LJ, Rassidakis GZ. mTOR signaling is activated by FLT3 kinase and promotes survival of FLT3-mutated acute myeloid leukemia cells. Mol Cancer. 2010 Nov 10; 9:292. PMID: 21067588; PMCID: PMC2993677.
      Citations: 41     Fields:    Translation:HumansCells
    25. Admirand JH, Knoblock RJ, Coombes KR, Tam C, Schlette EJ, Wierda WG, Ferrajoli A, O'Brien S, Keating MJ, Luthra R, Medeiros LJ, Abruzzo LV. Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression. Mod Pathol. 2010 Nov; 23(11):1518-23. PMID: 20657554; PMCID: PMC2966512.
      Citations: 11     Fields:    Translation:Humans
    26. Samanta AK, Chakraborty SN, Wang Y, Schlette E, Reddy EP, Arlinghaus RB. Destabilization of Bcr-Abl/Jak2 Network by a Jak2/Abl Kinase Inhibitor ON044580 Overcomes Drug Resistance in Blast Crisis Chronic Myelogenous Leukemia (CML). Genes Cancer. 2010 Apr; 1(4):346-59. PMID: 20798787; PMCID: PMC2927857.
      Citations: 22     
    27. Schlette EJ, Admirand J, Wierda W, Abruzzo L, Lin KI, O'Brien S, Lerner S, Keating MJ, Tam C. p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy. Leuk Lymphoma. 2009 Oct; 50(10):1597-605. PMID: 19863337; PMCID: PMC4428664.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    28. Lin KI, Tam CS, Keating MJ, Wierda WG, O'Brien S, Lerner S, Coombes KR, Schlette E, Ferrajoli A, Barron LL, Kipps TJ, Rassenti L, Faderl S, Kantarjian H, Abruzzo LV. Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens. Blood. 2009 Apr 02; 113(14):3168-71. PMID: 19050308; PMCID: PMC4916943.
      Citations: 36     Fields:    Translation:HumansCTClinical Trials
    29. Gunn SR, Mohammed MS, Gorre ME, Cotter PD, Kim J, Bahler DW, Preobrazhensky SN, Higgins RA, Bolla AR, Ismail SH, de Jong D, Eldering E, van Oers MH, Mellink CH, Keating MJ, Schlette EJ, Abruzzo LV, Robetorye RS. Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia. J Mol Diagn. 2008 Sep; 10(5):442-51. PMID: 18687794; PMCID: PMC2518739.
      Citations: 29     Fields:    Translation:HumansCells
    30. Huh YO, Lin KI, Vega F, Schlette E, Yin CC, Keating MJ, Luthra R, Medeiros LJ, Abruzzo LV. MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis. Br J Haematol. 2008 Jul; 142(1):36-44. PMID: 18477041.
      Citations: 22     Fields:    Translation:HumansCells
    31. Han X, Jorgensen JL, Brahmandam A, Schlette E, Huh YO, Shi Y, Awagu S, Chen W. Immunophenotypic study of basophils by multiparameter flow cytometry. Arch Pathol Lab Med. 2008 May; 132(5):813-9. PMID: 18466030.
      Citations: 23     Fields:    Translation:HumansCells
    32. Inamdar KV, Medeiros LJ, Jorgensen JL, Amin HM, Schlette EJ. Bone marrow involvement by marginal zone B-cell lymphomas of different types. Am J Clin Pathol. 2008 May; 129(5):714-22. PMID: 18426730.
      Citations: 3     Fields:    Translation:Humans
    33. Ferrajoli A, Lee BN, Schlette EJ, O'Brien SM, Gao H, Wen S, Wierda WG, Estrov Z, Faderl S, Cohen EN, Li C, Reuben JM, Keating MJ. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood. 2008 Jun 01; 111(11):5291-7. PMID: 18334676; PMCID: PMC4082321.
      Citations: 147     Fields:    Translation:HumansCellsCTClinical Trials
    34. Cotta CV, Leventaki V, Atsaves V, Vidaki A, Schlette E, Jones D, Medeiros LJ, Rassidakis GZ. The helix-loop-helix protein Id2 is expressed differentially and induced by myc in T-cell lymphomas. Cancer. 2008 Feb 01; 112(3):552-61. PMID: 18085637.
      Citations: 11     Fields:    Translation:HumansCells
    35. Catrina Reading F, Schlette EJ, Stewart JM, Keating MJ, Katz RL, Caraway NP. Fine-needle aspiration biopsy findings in patients with small lymphocytic lymphoma transformed to hodgkin lymphoma. Am J Clin Pathol. 2007 Oct; 128(4):571-8. PMID: 17875507.
      Citations: 2     Fields:    Translation:HumansCells
    36. Alvarado Y, Welch MA, Swords R, Bruzzi J, Schlette E, Giles FJ. Nelarabine activity in acute biphenotypic leukemia. Leuk Res. 2007 Nov; 31(11):1600-3. PMID: 17512588.
      Citations: 2     Fields:    Translation:Humans
    37. Drakos E, Leventaki V, Schlette EJ, Jones D, Lin P, Medeiros LJ, Rassidakis GZ. c-Jun expression and activation are restricted to CD30+ lymphoproliferative disorders. Am J Surg Pathol. 2007 Mar; 31(3):447-53. PMID: 17325487.
      Citations: 15     Fields:    Translation:HumansCells
    38. Huh YO, Abruzzo LV, Rassidakis GZ, Parry-Jones N, Schlette E, Brito-Bapabulle V, Matutes E, Wotherspoon A, Keating MJ, Medeiros LJ, Catovsky D. The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases. Br J Haematol. 2007 Jan; 136(2):220-8. PMID: 17129229.
      Citations: 8     Fields:    Translation:HumansCells
    39. Akyurek N, Ren Y, Rassidakis GZ, Schlette EJ, Medeiros LJ. Expression of inhibitor of apoptosis proteins in B-cell non-Hodgkin and Hodgkin lymphomas. Cancer. 2006 Oct 15; 107(8):1844-51. PMID: 16983704.
      Citations: 21     Fields:    Translation:HumansCells
    40. Ren Y, Akyurek N, Schlette E, Rassidakis GZ, Medeiros LJ. Expression of Smac/DIABLO in B-cell non-Hodgkin and Hodgkin lymphomas. Hum Pathol. 2006 Nov; 37(11):1407-13. PMID: 16949641.
      Citations: 2     Fields:    Translation:HumansCells
    41. Onciu M, Schlette E, Zhou Y, Raimondi SC, Giles FJ, Kantarjian HM, Medeiros LJ, Ribeiro RC, Pui CH, Sandlund JT. Secondary chromosomal abnormalities predict outcome in pediatric and adult high-stage Burkitt lymphoma. Cancer. 2006 Sep 01; 107(5):1084-92. PMID: 16862570.
      Citations: 10     Fields:    Translation:Humans
    42. Tsimberidou AM, Catovsky D, Schlette E, O'Brien S, Wierda WG, Kantarjian H, Garcia-Manero G, Wen S, Do KA, Lerner S, Keating MJ. Outcomes in patients with splenic marginal zone lymphoma and marginal zone lymphoma treated with rituximab with or without chemotherapy or chemotherapy alone. Cancer. 2006 Jul 01; 107(1):125-35. PMID: 16700034.
      Citations: 20     Fields:    Translation:Humans
    43. Schlette E, Rassidakis GZ, Canoz O, Medeiros LJ. Expression of bcl-3 in chronic lymphocytic leukemia correlates with trisomy 12 and abnormalities of chromosome 19. Am J Clin Pathol. 2005 Mar; 123(3):465-71. PMID: 15716244.
      Citations: 6     Fields:    Translation:HumansCells
    44. Schlette EJ, Medeiros LJ, Goy A, Lai R, Rassidakis GZ. Survivin expression predicts poorer prognosis in anaplastic large-cell lymphoma. J Clin Oncol. 2004 May 01; 22(9):1682-8. PMID: 15117990.
      Citations: 44     Fields:    Translation:HumansCells
    45. Schlette E, Fu K, Medeiros LJ. CD23 expression in mantle cell lymphoma: clinicopathologic features of 18 cases. Am J Clin Pathol. 2003 Nov; 120(5):760-6. PMID: 14608904.
      Citations: 16     Fields:    Translation:Humans
    46. Schlette E, Medeiros LJ, Keating M, Lai R. CD79b expression in chronic lymphocytic leukemia. Association with trisomy 12 and atypical immunophenotype. Arch Pathol Lab Med. 2003 May; 127(5):561-6. PMID: 12708898.
      Citations: 2     Fields:    Translation:HumansCells
    47. Schlette E, Medeiros LJ, Beran M, Bueso-Ramos CE. Indolent neuroendocrine tumor involving the bone marrow. A case report with a 9-year follow-up. Arch Pathol Lab Med. 2003 Apr; 127(4):488-91. PMID: 12683882.
      Citations: 2     Fields:    Translation:Humans
    48. Merchant S, Schlette E, Sanger W, Lai R, Medeiros LJ. Mature B-cell leukemias with more than 55% prolymphocytes: report of 2 cases with Burkitt lymphoma-type chromosomal translocations involving c-myc. Arch Pathol Lab Med. 2003 Mar; 127(3):305-9. PMID: 12653573.
      Citations: 3     Fields:    Translation:HumansCells
    49. Hao S, Sanger W, Onciu M, Lai R, Schlette EJ, Medeiros LJ. Mantle cell lymphoma with 8q24 chromosomal abnormalities: a report of 5 cases with blastoid features. Mod Pathol. 2002 Dec; 15(12):1266-72. PMID: 12481006.
      Citations: 26     Fields:    Translation:HumansCells
    50. Onciu M, Schlette E, Bueso-Ramos C, Medeiros LJ. Leukemic mantle cell lymphoma with cells resembling prolymphocytes. Am J Clin Pathol. 2002 Aug; 118(2):305-6; author reply 306. PMID: 12162692.
      Citations:    Fields:    Translation:HumansCells
    51. Veillon DM, Nordberg ML, Glass J, Sattar T, Cotelingam JD. Prolymphocytic leukemia or prolymphocytic transformation of mantle cell lymphoma. Am J Clin Pathol. 2001 Nov; 116(5):781-2. PMID: 11710698.
      Citations:    Fields:    Translation:Humans
    52. Schlette E, Lai R, Onciu M, Doherty D, Bueso-Ramos C, Medeiros LJ. Leukemic mantle cell lymphoma: clinical and pathologic spectrum of twenty-three cases. Mod Pathol. 2001 Nov; 14(11):1133-40. PMID: 11706075.
      Citations: 3     Fields:    Translation:HumansCells
    53. Dabaja BS, O'Brien SM, Kantarjian HM, Cortes JE, Thomas DA, Albitar M, Schlette ES, Faderl S, Sarris A, Keating MJ, Giles FJ. Fractionated cyclophosphamide, vincristine, liposomal daunorubicin (daunoXome), and dexamethasone (hyperCVXD) regimen in Richter's syndrome. Leuk Lymphoma. 2001 Jul; 42(3):329-37. PMID: 11699397.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    54. Donor-derived T-cell large granular lymphocytic leukemia in a patient with peripheral T-cell lymphoma. JNCCN Journal of the National Comprehensive Cancer Network. 14:939-944.
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