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VERSTOVSEK, SRDAN
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SRDAN VERSTOVSEK
Title
Professor
Institution
MD Anderson
Department
Leukemia
Address
1400 Holcombe Blvd
Houston TX 77030-4008
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Pemmaraju N
,
Bose P
, Rampal R, Gerds AT, Fleischman A,
Verstovsek S
. Ten years after ruxolitinib approval for myelofibrosis: a review of clinical efficacy. Leuk Lymphoma. 2023 Apr 20; 1-19.
PMID:
37081809
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Vachhani P,
Verstovsek S
,
Bose P
. Cytopenic myelofibrosis: prevalence, relevance, and treatment. Expert Opin Pharmacother. 2023 Jun; 24(8):901-912.
PMID:
37070147
.
Citations:
Fields:
Pha
Pharmacology
Verstovsek S
, Mesa RA, Gupta V, Lavie D, Dubruille V, Cambier N, Platzbecker U, Hus M, Xicoy B, Oh ST, Kiladjian JJ, Vannucchi AM, Gerds AT, Egyed M, Mayer J, Sacha T, Kawashima J, Morris M, Huang M, Harrison CN. Momelotinib Long-Term Safety and Survival in Myelofibrosis: Integrated Analysis of Phase 3 Randomized-Controlled Trials. Blood Adv. 2023 Apr 12.
PMID:
37042865
.
Citations:
Fields:
Hem
Hematology
Mesa RA, Hudgens S, Floden L, Harrison CN, Palmer J, Gupta V, McLornan DP, McMullin MF, Kiladjian JJ, Foltz L, Platzbecker U, Fox ML, Mead AJ, Ross DM, Oh ST, Perkins A, Leahy MF, Deheshi S, Donahue R, Klencke BJ,
Verstovsek S
. Symptomatic benefit of momelotinib in patients with myelofibrosis: Results from the SIMPLIFY phase III studies. Cancer Med. 2023 Apr 06.
PMID:
37021939
.
Citations:
Fields:
Neo
Neoplasms
Krecak I, Skelin M,
Verstovsek S
. Evaluating ropeginterferon alfa-2b for the treatment of adults with polycythemia vera. Expert Rev Hematol. 2023 05; 16(5):305-316.
PMID:
37002907
.
Citations:
Fields:
Hem
Hematology
Babakhanlou R,
Verstovsek S
,
Pemmaraju N
, Rojas-Hernandez CM. Secondary erythrocytosis. Expert Rev Hematol. 2023 04; 16(4):245-251.
PMID:
36927204
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
Mascarenhas J, Kremyanskaya M, Patriarca A, Palandri F, Devos T, Passamonti F, Rampal RK, Mead AJ, Hobbs G, Scandura JM, Talpaz M, Granacher N, Somervaille TCP, Hoffman R, Wondergem MJ, Salama ME, Colak G, Cui J, Kiladjian JJ, Vannucchi AM,
Verstovsek S
, Curto-Garc?a N, Harrison C, Gupta V. MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Na?ve Myelofibrosis. J Clin Oncol. 2023 Mar 07; JCO2201972.
PMID:
36881782
.
Citations:
Fields:
Neo
Neoplasms
Verstovsek S
, Kiladjian JJ, Vannucchi AM, Mesa RA, Squier P, Hamer-Maansson JE, Harrison C. Early intervention in myelofibrosis and impact on outcomes: A pooled analysis of the COMFORT-I and COMFORT-II studies. Cancer. 2023 Jun 01; 129(11):1681-1690.
PMID:
36840971
.
Citations:
1
Fields:
Neo
Neoplasms
Verstovsek S
. How I manage anemia related to myelofibrosis and its treatment regimens. Ann Hematol. 2023 Apr; 102(4):689-698.
PMID:
36786879
; PMCID:
PMC9998582
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Babakhanlou R, Masarova L,
Verstovsek S
. A review of essential thrombocythemia and its complications. Clin Adv Hematol Oncol. 2023 Feb; 21(2):76-84.
PMID:
36780473
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
PH
Public Health
Verstovsek S
, Gerds AT, Vannucchi AM, Al-Ali HK, Lavie D, Kuykendall AT, Grosicki S, Iurlo A, Goh YT, Lazaroiu MC, Egyed M, Fox ML, McLornan D, Perkins A, Yoon SS, Gupta V, Kiladjian JJ, Granacher N, Lee SE, Ocroteala L, Passamonti F, Harrison CN, Klencke BJ, Ro S, Donahue R, Kawashima J, Mesa R, MOMENTUM Study Investigators. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study. Lancet. 2023 01 28; 401(10373):269-280.
PMID:
36709073
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Verstovsek S
,
Pemmaraju N
, Reaven NL, Funk SE, Woody T, Valone F, Gupta S. Real-world treatments and thrombotic events in polycythemia vera patients in the USA. Ann Hematol. 2023 Mar; 102(3):571-581.
PMID:
36637474
; PMCID:
PMC9977710
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Al-Ghamdi YA, Lake J, Bagg A,
Thakral B
, Wang SA,
Bueso-Ramos C
, Masarova L,
Verstovsek S
, Rogers HJ, Hsi ED, Gralewski JH, Chabot-Richards D, George TI, Rets A, Hasserjian RP, Weinberg OK, Parilla M, Arber DA, Padilla O, Orazi A, Tam W. Triple-Negative Primary Myelofibrosis: A Bone Marrow Pathology Group Study. Mod Pathol. 2023 03; 36(3):100016.
PMID:
36788093
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Chifotides HT, Masarova L,
Verstovsek S
. SOHO State of the Art Updates and Next Questions: Novel Therapeutic Strategies in Development for Myelofibrosis. Clin Lymphoma Myeloma Leuk. 2023 04; 23(4):219-231.
PMID:
36797153
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Polverelli N, Hern?ndez-Boluda JC, Czerw T, Barbui T, D'Adda M, Deeg HJ, Ditschkowski M, Harrison C, Kr?ger NM, Mesa R, Passamonti F, Palandri F,
Pemmaraju N
,
Popat U
, Rondelli D, Vannucchi AM,
Verstovsek S
, Robin M, Colecchia A, Grazioli L, Damiani E, Russo D, Brady J, Patch D, Blamek S, Damaj GL, Hayden P, McLornan DP, Yakoub-Agha I. Splenomegaly in patients with primary or secondary myelofibrosis who are candidates for allogeneic hematopoietic cell transplantation: a Position Paper on behalf of the Chronic Malignancies Working Party of the EBMT. Lancet Haematol. 2022 Dec 06.
PMID:
36493799
.
Citations:
Mascarenhas J, Gleitz HFE, Chifotides HT, Harrison CN,
Verstovsek S
, Vannucchi AM, Rampal RK, Kiladjian JJ, Vainchenker W, Hoffman R, Schneider RK, List AF. Biological drivers of clinical phenotype in myelofibrosis. Leukemia. 2023 02; 37(2):255-264.
PMID:
36434065
; PMCID:
PMC9898039
.
Citations:
Verstovsek S
, Al-Ali HK, Mascarenhas J, Perkins A, Vannucchi AM, Mohan SR, Scott BL, Woszczyk D, Koschmieder S, Garc?a-Delgado R, L?szl? R, McGreivy JS, Rothbaum WP, Kiladjian JJ. BOREAS: a?global, phase III study of the MDM2 inhibitor navtemadlin (KRT-232) in relapsed/refractory myelofibrosis. Future Oncol. 2022 Nov 23.
PMID:
36416118
.
Citations:
Passamonti F, Harrison CN, Mesa RA, Kiladjian JJ, Vannucchi AM,
Verstovsek S
. Anemia in myelofibrosis: Current and emerging treatment options. Crit Rev Oncol Hematol. 2022 Dec; 180:103862.
PMID:
36332787
.
Citations:
Pemmaraju N
, Harrison C, Gupta V,
Verstovsek S
, Scott B, Oh ST, Palandri F, Al-Ali HK, Sobas M, McMullin MF, Mesa R, Buckley S, Roman-Torres K, Vannucchi A, Yacoub A. Risk-adjusted safety analysis of the oral JAK2/IRAK1 inhibitor pacritinib in patients with myelofibrosis. EJHaem. 2022 Nov; 3(4):1346-1351.
PMID:
36467816
; PMCID:
PMC9713029
.
Citations:
Harrison C,
Bose P
, Mesa R, Gerds A, Oh S, Kiladijan JJ, Garcia-Gutierrez V, Vannucchi A, Scheid C, Sobas M,
Verstovsek S
, Buckley S, Roman-Torres K, Mascarenhas J. MPN-141 Retrospective Comparison of Patient Outcomes on Pacritinib Versus Ruxolitinib in Patients With Myelofibrosis and Thrombocytopenia. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S326-S327.
PMID:
36163987
.
Citations:
Oh S, Mesa R, Harrison C,
Bose P
, Gerds A, Gupta V, Swami A, Tyavanagimatt S, Buckley S, Roman-Torres K,
Verstovsek S
. MPN-145 Retrospective Analysis of Anemia Benefit of Pacritinib From the PERSIST-2 Trial. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S327.
PMID:
36163989
.
Citations:
Zavidij O, Haradhvala NJ, Meyer R, Cui J,
Verstovsek S
, Oh S, Mead A, Taverna P. MPN-238 Single-Cell RNA Profiling of Myelofibrosis Patients Reveals Pelabresib-Induced Decrease of Megakaryocytic Progenitors and Normalization of CD4+ T Cells in Peripheral Blood. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S331-S332.
PMID:
36163997
.
Citations:
Masarova L,
Bose P
,
Pemmaraju N
,
Kantarjian H
,
Estrov Z
,
Verstovsek S
. MPN-354 Characteristics of Patients With Myelofibrosis Taking Ruxolitinib for 3 or More Years. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S334.
PMID:
36164003
.
Citations:
Masarova L,
Bose P
,
Pemmaraju N
,
Kantarjian H
,
Estrov Z
,
Verstovsek S
. MPN-355 Patients With Prefibrotic Myelofibrosis and Inferior Outcome, a Single-Center Analysis. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S334-S335.
PMID:
36164004
.
Citations:
Mascarenhas J, Kremyanskaya M, Patriarca A, Harrison C,
Bose P
, Rampal RK, Palandri F, Devos T, Passamonti F, Hobbs G, Talpaz M, Vannucchi A, Kiladjian JJ,
Verstovsek S
, Hoffman R, Salama ME, Chen D, Taverna P, Chang A, Colak G, Klein S, Gupta V. MPN-375 BET Inhibitor Pelabresib (CPI-0610) Combined With Ruxolitinib in Patients With Myelofibrosis - JAK Inhibitor-Na?e or With Suboptimal Response to Ruxolitinib - Preliminary Data From the MANIFEST Study. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S335-S336.
PMID:
36164005
.
Citations:
Gupta V, Mascarenhas J, Kremyanskaya M, Rampal RK, Talpaz M, Kiladjian JJ, Vannucchi A,
Verstovsek S
, Colak G, Dey D, Harrison C. MPN-379 Matching-Adjusted Indirect Comparison (MAIC) of Pelabresib (CPI-0610) in Combination With Ruxolitinib vs. JAK Inhibitor Monotherapy in Patients With Intermediate or High-Risk Myelofibrosis. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S336.
PMID:
36164007
.
Citations:
Pemmaraju N
, Kuykendall A, Kremyanskaya M, Ginzburg Y, Ritchie E, Gotlib J, Gerds A, Palmer J, Valone F, O'Connor P, Modi N, Gupta S, Hoffman R,
Verstovsek S
. MPN-469 Rusfertide (PTG-300) Treatment Interruption Reverses Hematological Gains and Upon Reinitiation, Restoration of Clinical Benefit Observed in Patients With Polycythemia Vera. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S338-S339.
PMID:
36164011
.
Citations:
Mesa R, Gerds A, Vannucchi A, Al-Ali HK, Lavie D, Kuykendall A, Grosicki S, Iurlo A, Goh YT, Lazaroiu M, Egyed M, Fox ML, McLornan D, Perkins A, Yoon SS, Gupta V, Kiladjian JJ, Donahue R, Kawashima J,
Verstovsek S
. MPN-478 MOMENTUM: Phase 3 Randomized Study of Momelotinib (MMB) versus Danazol (DAN) in Symptomatic and Anemic Myelofibrosis (MF) Patients Previously Treated With a JAK Inhibitor. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S339-S340.
PMID:
36164012
.
Citations:
Gerds A,
Verstovsek S
, Vannucchi A, Al-Ali HK, Lavie D, Kuykendall A, Grosicki S, Iurlo A, Goh YT, Lazaroiu M, Egyed M, Fox ML, McLornan D, Perkins A, Yoon SS, Gupta V, Kiladjian JJ, Donahue R, Kawashima J, Mesa R. MPN-483 Thrombocytopenic Myelofibrosis (MF) Patients Previously Treated With a JAK Inhibitor in a Phase 3 Randomized Study of Momelotinib (MMB) versus Danazol (DAN) [MOMENTUM]. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S340.
PMID:
36164014
.
Citations:
Verstovsek S
, Mesa R, Mascarenhas J, Tashi T, Shih W, Sato T, Urbanski R, Zagrijtschuk O, Zimmerman C. MPN-546 A Single-Arm Multicenter Study to Assess the Efficacy, Safety, and Tolerability of Ropeginterferon alfa-2b-njft (P1101) in North American Adults With Essential Thrombocythemia. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S342-S343.
PMID:
36164018
.
Citations:
Mesa R, Komatsu N, Gill H, Jin J, Lee SE, Hou HA, Sato T, Qin A, Urbanski R, Shih W, Zagrijtschuk O, Zimmerman C,
Verstovsek S
. MPN-545 Surpass-ET: Ropeginterferon Alfa-2b (P1101) vs. Anagrelide as Second Line Therapy in Essential Thrombocythemia. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S342.
PMID:
36164019
.
Citations:
Chifotides HT,
Verstovsek S
. EXABS-164-MPN Novel Therapeutics in Development for Myelofibrosis. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S72-S74.
PMID:
36164238
.
Citations:
Torres HA
, Angelidakis G, Jiang Y, Economides M, Mustafayev K, Yibirin M,
Orlowski R
,
Champlin R
,
Verstovsek S
,
Raad I
. Serologic versus molecular testing for screening for hepatitis C virus infection in patients with hematologic malignancies. Medicine (Baltimore). 2022 Sep 16; 101(37):e30608.
PMID:
36123927
; PMCID:
PMC9478288
.
Citations:
Guglielmelli P, Kiladjian JJ, Vannucchi AM, Duan M, Meng H, Pan L, He G,
Verstovsek S
, Boyer F, Barraco F, Niederwieser D, Pungolino E, Liberati AM, Harrison C, Roussou P, Wroclawska M, Karumanchi D, Sinclair K, Te Boekhorst PAW, Gisslinger H. Efficacy and safety of ruxolitinib in patients with myelofibrosis and low platelet count (50???109/L to <100???109/L) at baseline: the final analysis of EXPAND. Ther Adv Hematol. 2022; 13:20406207221118429.
PMID:
36105914
; PMCID:
PMC9465569
.
Citations:
Harrison CN, Gupta VK, Gerds AT, Rampal R,
Verstovsek S
, Talpaz M, Kiladjian JJ, Mesa R, Kuykendall AT, Vannucchi AM, Palandri F, Grosicki S, Devos T, Jourdan E, Wondergem MJ, Al-Ali HK, Buxhofer-Ausch V, Alvarez-Larr?n A, Patriarca A, Kremyanskaya M, Mead AJ, Akhani S, Sheikine Y, Colak G, Mascarenhas J. Phase III MANIFEST-2: pelabresib?+ ruxolitinib vs placebo?+ ruxolitinib in JAK inhibitor treatment-naive myelofibrosis. Future Oncol. 2022 Sep; 18(27):2987-2997.
PMID:
35950489
.
Citations:
Krecak I, Lucijanic M,
Verstovsek S
. Advances in Risk Stratification and Treatment of Polycythemia Vera and Essential Thrombocythemia. Curr Hematol Malig Rep. 2022 10; 17(5):155-169.
PMID:
35932395
.
Citations:
Verstovsek S
, Komatsu N, Gill H, Jin J, Lee SE, Hou HA, Sato T, Qin A, Urbanski R, Shih W, Zagrijtschuk O, Zimmerman C, Mesa RA. SURPASS-ET: phase III study of ropeginterferon alfa-2b versus anagrelide as second-line therapy in essential thrombocythemia. Future Oncol. 2022 Sep; 18(27):2999-3009.
PMID:
35924546
.
Citations:
Mesa R, Harrison C, Oh ST, Gerds AT, Gupta V, Catalano J, Cervantes F, Devos T, Hus M, Lech-Maranda E, McLornan D, Vannucchi AM, Platzbecker U, Huang M, Strouse B, Klencke B,
Verstovsek S
, Kiladjian JJ. Overall survival in the SIMPLIFY-1 and SIMPLIFY-2 phase 3 trials of momelotinib in patients with myelofibrosis. Leukemia. 2022 09; 36(9):2261-2268.
PMID:
35869266
; PMCID:
PMC9417985
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
El Hussein S, Chifotides HT,
Khoury JD
,
Verstovsek S
,
Thakral B
. Systemic Mastocytosis and Other Entities Involving Mast Cells: A Practical Review and Update. Cancers (Basel). 2022 Jul 17; 14(14).
PMID:
35884535
; PMCID:
PMC9322501
.
Citations:
Senapati J,
Verstovsek S
, Masarova L,
Pemmaraju N
,
Patel KP
, Montalban-Bravo G, Pierce SA, Zhou L,
Garcia-Manero G
,
Kantarjian HM
,
Bose P
. Impact of SF3B1 mutation in myelofibrosis. Leuk Lymphoma. 2022 11; 63(11):2701-2705.
PMID:
35787095
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Verstovsek S
, Mesa R, Talpaz M, Kiladjian JJ, Harrison CN, Oh ST, Vannucchi AM, Rampal R, Scott BL, Buckley SA, Craig AR, Roman-Torres K, Mascarenhas JO. Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia. Haematologica. 2022 07 01; 107(7):1599-1607.
PMID:
34551507
; PMCID:
PMC9244834
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Kosiorek HE, Scherber RM, Geyer HL,
Verstovsek S
, Langlais BT, Mazza GL, Gotlib J, Gupta V, Padrnos LJ, Palmer JM, Fleischman A, Mesa RA, Dueck AC. Quality of life independently predicts overall survival in myelofibrosis: Key insights from the COntrolled MyeloFibrosis Study with ORal Janus kinase inhibitor Treatment (COMFORT)-I study. Br J Haematol. 2022 09; 198(6):1065-1068.
PMID:
35751150
.
Citations:
Fields:
Hem
Hematology
Khoury JD
, Abla O, Akkari Y, Alaggio R, Apperley JF, Bejar R, Chan JKC, Chen W, Chen X, Chng WJ, Choi JK, Coupland SE, Cross NCP, De Jong D,
Elghetany MT
, Takahashi E, Emile JF, Ferry J, Fogelstrand L, Gujral S, Haferlach T, Harrison C, Hodge JC, Hu S, Jansen JH, Kanagal-Shamanna R,
Kantarjian HM
, Kratz CP, Li XQ, Lim MS, Loeb K,
Loghavi S
,
Marcogliese A
, Meshinchi S, Michaels P, Naresh KN, Natkunam Y, Nejati R, Ott G, Padron E,
Patel KP
, Patkar N, Picarsic J, Platzbecker U, Roberts I, Schuh A, Sewell W, Siebert R, Tembhare P, Tyner J,
Verstovsek S
, Wang W, Wood B, Xiao W, Yeung C, Solary E, Berti E, Busque L, Colmenero I, Fontenay M, Germing U, Hochhaus A. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic?Neoplasms. Leukemia. 2022 07; 36(7):1703-1719.
PMID:
35732831
; PMCID:
PMC9252913
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Tashakori M,
Khoury JD
,
Routbort MJ
,
Patel KP
, Wang SA,
Ok CY
, El-Hussein S, Kanagal-Shamanna R,
Luthra R
, Hu S, Lin P,
Pemmaraju N
,
Bose P
,
Verstovsek S
,
Bueso-Ramos CE
,
Medeiros LJ
,
Loghavi S
. Clinicopathologic spectrum of myeloid neoplasms with concurrent myeloproliferative neoplasm driver mutations and SRSF2 mutations. Mod Pathol. 2022 11; 35(11):1677-1683.
PMID:
35690645
.
Citations:
Fields:
Pat
Pathology
Verstovsek S
. Cases in the management of polycythemia vera: switching from hydroxyurea to ruxolitinib to resolve symptoms and improve quality of life. Clin Adv Hematol Oncol. 2022 06; 20 Suppl 11(6):1-12.
PMID:
35772008
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Wang X, Tang G, Hu Z, Fang H, Wang W,
Tang Z
, Toruner GA, Zhou T,
DiNardo CD
,
Garcia-Manero G
,
Verstovsek S
,
Bueso-Ramos CE
,
Medeiros LJ
, Hu S. Myeloid neoplasms with 8q24/MYC rearrangement are frequently associated with myelodysplasia, complex karyotype, TP53 alterations, and inferior survival. Br J Haematol. 2022 08; 198(3):604-608.
PMID:
35645146
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Rozovski U, Veletic I, Harris DM, Li P, Liu Z, Jain P, Manshouri T,
Ferrajoli A
,
Burger JA
,
Bose P
, Thompson PA,
Jain N
,
Wierda WG
,
Verstovsek S
, Keating MJ,
Estrov Z
. STAT3 Activates the Pentraxin 3 Gene in Chronic Lymphocytic Leukemia Cells. J Immunol. 2022 06 15; 208(12):2847-2855.
PMID:
35595309
; PMCID:
PMC9308680
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Manshouri T, Veletic I, Li P, Yin CC,
Post SM
,
Verstovsek S
,
Estrov Z
. GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes. Cell Death Dis. 2022 May 20; 13(5):481.
PMID:
35595725
; PMCID:
PMC9122946
.
Citations:
Fields:
Cel
Cell Biology
Int
Internal Medicine
Translation:
Humans
Animals
Pemmaraju N
, Garcia JS, Potluri J, Harb JG, Sun Y, Jung P, Qin QQ, Tantravahi SK,
Verstovsek S
, Harrison C. Addition of navitoclax to ongoing ruxolitinib treatment in patients with myelofibrosis (REFINE): a post-hoc analysis of molecular biomarkers in a phase 2 study. Lancet Haematol. 2022 Jun; 9(6):e434-e444.
PMID:
35576960
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Mascarenhas J, Harrison CN, Komrokji RS, Koschmieder S, Vannucchi AM, Berry T, Redding D, Sherman L, Dougherty S, Peng L, Sun L, Huang F, Wan Y, Feller FM, Rizo A,
Verstovsek S
, Kiladjian JJ. Imetelstat in intermediate-2 or high-risk myelofibrosis refractory to JAK inhibitor: IMpactMF phase III study design. Future Oncol. 2022 Jul; 18(22):2393-2402.
PMID:
35510486
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Pemmaraju N
,
Verstovsek S
, Mesa R, Gupta V, Garcia JS, Scandura JM, Oh ST, Passamonti F, Mead AJ, D?hner K. Defining disease modification in myelofibrosis in the era of targeted therapy. Cancer. 2022 07 01; 128(13):2420-2432.
PMID:
35499819
; PMCID:
PMC9322520
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
. How early intervention impacts long-term survival in myelofibrosis. Clin Adv Hematol Oncol. 2022 05; 20(5):291-294.
PMID:
35579587
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Kanagal-Shamanna R, Orazi A, Hasserjian RP, Arber DA, Reichard K, Hsi ED, Bagg A, Rogers HJ, Geyer J, Darbaniyan F,
Do KA
, Devins KM, Pozdnyakova O, George TI, Cin PD, Greipp PT,
Routbort MJ
, Patel K,
Garcia-Manero G
,
Verstovsek S
,
Medeiros LJ
, Wang SA,
Bueso-Ramos C
. Correction to: Myelodysplastic/myeloproliferative neoplasms-unclassifiable with isolated isochromosome 17q represents a distinct clinico-biologic subset: a multi-institutional collaborative study from the Bone Marrow Pathology Group. Mod Pathol. 2022 May; 35(5):705.
PMID:
34903824
.
Citations:
Fields:
Pat
Pathology
Harrison CN, Schaap N, Vannucchi AM, Passamonti F, Zweegman S, Talpaz M,
Verstovsek S
, Rose S, Zhang J, Sy O, Mesa RA, Kiladjian JJ. Safety and efficacy of fedratinib, a selective oral inhibitor of Janus kinase-2 (JAK2), in patients with myelofibrosis and low pretreatment platelet counts. Br J Haematol. 2022 07; 198(2):317-327.
PMID:
35476316
; PMCID:
PMC9541243
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Lucijanic M,
Verstovsek S
, Krecak I, Celic-Bunikic S, Skelin M, Ku?ec R. Concomitant multiple sclerosis and polycythemia vera successfully treated with glatiramer acetate. Ann Hematol. 2022 08; 101(8):1885-1886.
PMID:
35461396
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Mughal TI,
Pemmaraju N
, Bejar R, Gale RP,
Bose P
, Prchal J, Royston D, Pollyea D, Valent P, Skorski T, Patnaik M, Santini V, Kucine N,
Verstovsek S
, Mesa R, Barbui T, Saglio G, Van Etten RA, Kiladjian JJ, Br?mmendorf TH, Fenaux P. Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies. Hematol Oncol. 2022 Oct; 40(4):491-504.
PMID:
35368098
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Mascarenhas JO,
Verstovsek S
. The clinical dilemma of JAK inhibitor failure in myelofibrosis: Predictive characteristics and outcomes. Cancer. 2022 07 15; 128(14):2717-2727.
PMID:
35385124
; PMCID:
PMC9324085
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Yilmaz M,
Verstovsek S
. Managing patients with myelofibrosis and thrombocytopenia. Expert Rev Hematol. 2022 03; 15(3):233-241.
PMID:
35316110
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Fountain E, Cheng L,
Verstovsek S
, Rojas-Hernandez CM, Barrios-Ruiz A, Davila-Gonzalez D. Potential limitations of diagnostic standard codes to distinguish polycythemia vera and secondary erythrocytosis. Sci Rep. 2022 03 18; 12(1):4674.
PMID:
35304527
; PMCID:
PMC8933419
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Mesa R, Oh ST, Gerds AT, Gupta V, Catalano J, Devos T, Hus M, Lech-Maranda E, McLornan D, Palmer J, Platzbecker U, Trelinski J, Shimoda K, Donahue R, D'Hollander K, Kowalski M,
Verstovsek S
, Cervantes F, Kiladjian JJ. Momelotinib reduces transfusion requirements in patients with myelofibrosis. Leuk Lymphoma. 2022 07; 63(7):1718-1722.
PMID:
35255234
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Harrison CN, Garcia JS, Somervaille TCP, Foran JM,
Verstovsek S
, Jamieson C, Mesa R, Ritchie EK, Tantravahi SK, Vachhani P, O'Connell CL, Komrokji RS, Harb J, Hutti JE, Holes L, Masud AA, Nuthalapati S, Potluri J,
Pemmaraju N
. Addition of Navitoclax to Ongoing Ruxolitinib Therapy for Patients With Myelofibrosis With Progression or Suboptimal Response: Phase II Safety and Efficacy. J Clin Oncol. 2022 05 20; 40(15):1671-1680.
PMID:
35180010
; PMCID:
PMC9113204
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Pemmaraju N
, Gerds AT, Yu J, Parasuraman S, Shah A, Xi A, Kumar S, Scherber RM,
Verstovsek S
. Thrombotic events and mortality risk in patients with newly diagnosed polycythemia vera or essential thrombocythemia. Leuk Res. 2022 04; 115:106809.
PMID:
35220060
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Chen MM, Wang SA,
Verstovsek S
, Durrani SR, Rothenberg ME, Pongdee T, Butterfield J, Lax T, Wechsler ME, Stein ML, Ogbogu PU, Kahwash BM, Mathur SK, Simon D, Akuthota P, Holland N, Wetzler L, Ware JM, Guo C, Fay MP, Khoury P, Klion AD, Bochner BS, Roufosse F. An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinophilic Syndromes. J Allergy Clin Immunol Pract. 2022 05; 10(5):1217-1228.e3.
PMID:
35181548
; PMCID:
PMC9086180
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Gerds AT, Lyons RM, Colucci P, Kalafut P, Paranagama D,
Verstovsek S
. Disease and Clinical Characteristics of Patients With a Clinical Diagnosis of Myelofibrosis Enrolled in the MOST Study. Clin Lymphoma Myeloma Leuk. 2022 07; 22(7):e532-e540.
PMID:
35256316
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Fiskus W
, Manshouri T, Birdwell C, Mill CP, Masarova L,
Bose P
,
Kadia TM
,
Daver N
,
DiNardo CD
,
Borthakur G
,
Khoury JD
,
Verstovsek S
,
Bhalla KN
. Efficacy of CDK9 inhibition in therapy of post-myeloproliferative neoplasm (MPN) secondary (s) AML cells. Blood Cancer J. 2022 01 31; 12(1):23.
PMID:
35102145
; PMCID:
PMC8803998
.
Citations:
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Vachhani P,
Verstovsek S
,
Bose P
. Disease Modification in Myelofibrosis: An Elusive Goal? J Clin Oncol. 2022 04 10; 40(11):1147-1154.
PMID:
35084934
; PMCID:
PMC8987221
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Masarova L,
Bose P
,
Pemmaraju N
,
Daver NG
, Sasaki K, Chifotides HT, Zhou L,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Improved survival of patients with myelofibrosis in the last decade: Single-center experience. Cancer. 2022 04 15; 128(8):1658-1665.
PMID:
35077575
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Chifotides HT,
Bose P
,
Verstovsek S
. Momelotinib: an emerging treatment for myelofibrosis patients with anemia. J Hematol Oncol. 2022 01 19; 15(1):7.
PMID:
35045875
; PMCID:
PMC8772195
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Gerds AT, Yu J, Scherber RM, Paranagama D, Kish JK, Visaria J, Singhal M,
Verstovsek S
,
Pemmaraju N
. Ruxolitinib Re-Treatment in Patients with Myelofibrosis: Real-World Evidence on Patient Characteristics and Outcomes. Acta Haematol. 2022; 145(4):448-453.
PMID:
35008087
; PMCID:
PMC9393808
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Pasca S, Chifotides HT,
Verstovsek S
,
Bose P
. Mutational landscape of blast phase myeloproliferative neoplasms (MPN-BP) and antecedent MPN. Int Rev Cell Mol Biol. 2022; 366:83-124.
PMID:
35153007
.
Citations:
1
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
DeAngelo DJ, Radia DH, George TI, Robinson WA, Quiery AT, Drummond MW,
Bose P
, Hexner EO, Winton EF, Horny HP, Tugnait M, Schmidt-Kittler O, Evans EK, Lin HM, Mar BG,
Verstovsek S
, Deininger MW, Gotlib J. Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial. Nat Med. 2021 12; 27(12):2183-2191.
PMID:
34873347
; PMCID:
PMC8674134
.
Citations:
3
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
CT
Clinical Trials
Lucijanic M, Krecak I,
Verstovsek S
, Soric E, Galusic D, Perisa V, Peric MM, Zekanovic I, Kusec R, Holik H. Higher red blood cell distribution width predicts thrombosis risk in primary and secondary myelofibrosis. Ann Hematol. 2022 06; 101(6):1355-1357.
PMID:
34825960
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Cells
Kanagal-Shamanna R, Orazi A, Hasserjian RP, Arber DA, Reichard K, Hsi ED, Bagg A, Rogers HJ, Geyer J, Darbaniyan F,
Do KA
, Devins KM, Pozdnyakova O, George TI, Cin PD, Greipp PT,
Routbort MJ
, Patel K,
Garcia-Manero G
,
Verstovsek S
,
Medeiros LJ
, Wang SA,
Bueso-Ramos C
. Myelodysplastic/myeloproliferative neoplasms-unclassifiable with isolated isochromosome 17q represents a distinct clinico-biologic subset: a multi-institutional collaborative study from the Bone Marrow Pathology Group. Mod Pathol. 2022 04; 35(4):470-479.
PMID:
34775472
; PMCID:
PMC8967812
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Cells
Talpaz M, Prchal J, Afrin L, Arcasoy M, Hamburg S, Clark J, Kornacki D, Colucci P,
Verstovsek S
. Safety and Efficacy of Ruxolitinib in Patients with Myelofibrosis and Low Platelet Counts (50 - 100???109/L): Final Analysis of an Open-Label Phase 2 Study. Clin Lymphoma Myeloma Leuk. 2022 05; 22(5):336-346.
PMID:
34911667
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Shoukier M,
Borthakur G
,
Jabbour E
, Ravandi F,
Garcia-Manero G
,
Kadia T
, Matthews J, Masarova L,
Naqvi K
, Sasaki K,
Verstovsek S
, Cortes J. The effect of eltrombopag in managing thrombocytopenia associated with tyrosine kinase therapy in patients with chronic myeloid leukemia and myelofibrosis. Haematologica. 2021 11 01; 106(11):2853-2858.
PMID:
33054123
; PMCID:
PMC8561288
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Verstovsek S
, Yu J, Scherber RM, Verma S, Dieyi C, Chen CC, Parasuraman S. Changes in the incidence and overall survival of patients with myeloproliferative neoplasms between 2002 and 2016 in the United States. Leuk Lymphoma. 2022 03; 63(3):694-702.
PMID:
34689695
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ramos Perez JM,
Patel KP
,
Loghavi S
,
Garcia-Manero G
,
Borthakur G
,
Jabbour E
,
Wierda W
, Pierce S, Brandt M,
Kornblau S
,
Kadia T
,
Daver N
,
DiNardo CD
,
Jain N
, Yilmaz M, Short N,
Verstovsek S
,
Ferrajoli A
,
Andreeff M
,
Konopleva M
, Rivera D, McCue D,
Kantarjian HM
, Ravandi F. Value of measurable residual disease monitoring in patients with acute promyelocytic leukemia in the era of frontline 'chemotherapy-free' therapy. Leuk Lymphoma. 2022 03; 63(3):672-675.
PMID:
34668451
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Chifotides HT,
Bose P
, Masarova L,
Pemmaraju N
,
Verstovsek S
. SOHO State of the Art Updates and Next Questions: Novel Therapies in Development for Myelofibrosis. Clin Lymphoma Myeloma Leuk. 2022 04; 22(4):210-223.
PMID:
34840087
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Parasuraman S, Yu J, Shah A, Kumar S, Xi A, Harrison C. Real-world survival of US patients with intermediate- to high-risk myelofibrosis: impact of ruxolitinib approval. Ann Hematol. 2022 Jan; 101(1):131-137.
PMID:
34625831
; PMCID:
PMC8720739
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Verstovsek S
, Amoloja T, Scherber RM, Yu J. Real-world patient characteristics and treatment patterns of ruxolitinib among patients with advanced essential thrombocythemia at community clinical practice. Leuk Res. 2021 11; 110:106711.
PMID:
34624568
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Mascarenhas J, Gerds A,
Verstovsek S
. Paradigm shift: combination BET and JAK inhibition in myelofibrosis. Leukemia. 2021 12; 35(12):3361-3363.
PMID:
34480105
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Veletic I, Prijic S, Manshouri T, Nogueras-Gonzalez GM,
Verstovsek S
,
Estrov Z
. Altered T-cell subset repertoire affects treatment outcome of patients with myelofibrosis. Haematologica. 2021 09 01; 106(9):2384-2396.
PMID:
32732359
; PMCID:
PMC8409049
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
Pemmaraju N
,
Carter BZ
,
Bose P
,
Jain N
,
Kadia TM
,
Garcia-Manero G
,
Bueso-Ramos CE
,
DiNardo CD
, Bledsoe S,
Daver NG
,
Popat U
,
Konopleva MY
, Zhou L, Pierce S,
Estrov ZE
,
Borthakur GM
,
Ohanian M
, Qiao W, Masarova L, Wang X, Mak PY, Cortes J,
Jabbour E
,
Verstovsek S
. Final results of a phase 2 clinical trial of LCL161, an oral SMAC mimetic for patients with myelofibrosis. Blood Adv. 2021 08 24; 5(16):3163-3173.
PMID:
34424319
; PMCID:
PMC8405193
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Bose P
,
Verstovsek S
. Avapritinib for Systemic Mastocytosis. Expert Rev Hematol. 2021 08; 14(8):687-696.
PMID:
34289787
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Abou Dalle I,
Kantarjian H
,
Daver N
, Masarova L,
Pemmaraju N
, Bose P,
Garcia-Manero G
,
Verstovsek S
. Phase II study of single-agent nivolumab in patients with myelofibrosis. Ann Hematol. 2021 Dec; 100(12):2957-2960.
PMID:
34350483
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Srour SA,
Olson A
,
Ciurea SO
, Desai P,
Bashir Q
,
Oran B
,
Bose P
,
Mehta R
,
Patel KP
,
Pemmaraju N
,
Daver N
,
Verstovsek S
,
Champlin RE
,
Popat UR
. Mixed myeloid chimerism and relapse of myelofibrosis after allogeneic stem cell transplantation. Haematologica. 2021 07 01; 106(7):1988-1990.
PMID:
31296578
; PMCID:
PMC8252931
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Lee SS,
Verstovsek S
,
Pemmaraju N
. Novel Therapies in Myeloproliferative Neoplasms: Beyond JAK Inhibitor Monotherapy. J Immunother Precis Oncol. 2021 Aug; 4(3):117-128.
PMID:
35663101
; PMCID:
PMC9138435
.
Citations:
1
Bose P
,
Verstovsek S
. SOHO State of the Art Updates and Next Questions: Identifying and Treating "Progression" in Myelofibrosis. Clin Lymphoma Myeloma Leuk. 2021 10; 21(10):641-649.
PMID:
34272171
; PMCID:
PMC8565615
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Kadia TM
, Ravandi F,
Borthakur G
,
Konopleva M
,
DiNardo CD
,
Daver N
,
Pemmaraju N
, Kanagal-Shamanna R, Wang X, Huang X, Pierce S, Rausch C,
Burger J
,
Ferrajoli A
,
Jain N
,
Popat U
,
Estrov Z
,
Verstovsek S
,
Jabbour E
,
Garcia-Manero G
,
Kantarjian H
. Long-term results of low-intensity chemotherapy with clofarabine or cladribine combined with low-dose cytarabine alternating with decitabine in older patients with newly diagnosed acute myeloid leukemia. Am J Hematol. 2021 08 01; 96(8):914-924.
PMID:
33901324
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Fiskus W
, Mill CP, Nabet B, Perera D, Birdwell C, Manshouri T, Lara B,
Kadia TM
,
DiNardo C
,
Takahashi K
,
Daver N
,
Bose P
, Masarova L,
Pemmaraju N
,
Kornblau S
,
Borthakur G
, Montalban-Bravo G, Manero GG, Sharma S, Stubbs M, Su X, Green MR,
Coarfa C
,
Verstovsek S
,
Khoury JD
, Vakoc CR,
Bhalla KN
. Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells. Blood Cancer J. 2021 05 20; 11(5):98.
PMID:
34016956
; PMCID:
PMC8138012
.
Citations:
5
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Montalban-Bravo G, Kanagal-Shamanna R, Sasaki K, Masarova L,
Naqvi K
,
Jabbour E
,
DiNardo CD
,
Takahashi K
,
Konopleva M
,
Pemmaraju N
,
Kadia TM
, Ravandi F,
Daver N
,
Borthakur G
,
Estrov Z
,
Khoury JD
,
Loghavi S
, Soltysiak KA, Pierce S,
Bueso-Ramos C
,
Patel KP
,
Verstovsek S
,
Kantarjian HM
,
Bose P
,
Garcia-Manero G
. Clinicopathologic correlates and natural history of atypical chronic myeloid leukemia. Cancer. 2021 09 01; 127(17):3113-3124.
PMID:
33914911
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Mesa RA, Schaap N, Vannucchi AM, Passamonti F, Zweegman S, Talpaz M,
Verstovsek S
, Rose S, Abraham P, Lord-Bessen J, Tang D, Guo S, Ye X, Harrison CN, Kiladjian JJ. Patient-reported Effects of Fedratinib, an Oral, Selective Inhibitor of Janus Kinase 2, on Myelofibrosis-related Symptoms and Health-related Quality of Life in the Randomized, Placebo-controlled, Phase III JAKARTA Trial. Hemasphere. 2021 May; 5(5):e553.
PMID:
33969273
; PMCID:
PMC8096463
.
Citations:
Harrison CN, Schaap N, Vannucchi AM, Silver RT, Schouten HC, Passamonti F, Zweegman S, Talpaz M,
Verstovsek S
, Tang D, Abraham P, Lord-Bessen J, Rose S, Guo S, Liao W, Mesa RA, Kiladjian JJ, Jourdan E. Fedratinib Improves Myelofibrosis-related Symptoms and Health-related Quality of Life in Patients with Myelofibrosis Previously Treated with Ruxolitinib: Patient-reported Outcomes from the Phase II JAKARTA2 Trial. Hemasphere. 2021 May; 5(5):e562.
PMID:
33969275
; PMCID:
PMC8096470
.
Citations:
2
Masarova L,
DiNardo CD
,
Bose P
,
Pemmaraju N
,
Daver NG
,
Kadia TM
, Chifotides HT, Zhou L,
Borthakur G
,
Estrov Z
,
Konopleva M
,
Verstovsek S
. Single-center experience with venetoclax combinations in patients with newly diagnosed and relapsed AML evolving from MPNs. Blood Adv. 2021 04 27; 5(8):2156-2164.
PMID:
33885751
; PMCID:
PMC8095138
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Montalban-Bravo G, Kanagal-Shamanna R, Darbaniyan F, Siddiqui MT, Sasaki K,
Wei Y
, Yang H, Chien KS,
Naqvi K
,
Jabbour E
,
Kadia TM
,
Daver N
,
DiNardo C
, Ravandi F,
Pemmaraju N
,
Bose P
,
Verstovsek S
, Pierce S,
Bueso-Ramos C
, Patel K,
Do KA
,
Kantarjian H
,
Garcia-Manero G
. Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) and myelodysplastic syndrome with ring sideroblasts (MDS-RS). Am J Hematol. 2021 07 01; 96(7):E246-E249.
PMID:
33811786
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Shahin OA, Chifotides HT,
Bose P
, Masarova L,
Verstovsek S
. Accelerated Phase of Myeloproliferative Neoplasms. Acta Haematol. 2021; 144(5):484-499.
PMID:
33882481
; PMCID:
PMC8458218
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Maiti A,
DiNardo CD
, Wang SA,
Jorgensen J
,
Kadia TM
,
Daver NG
, Short NJ, Yilmaz M,
Pemmaraju N
,
Borthakur G
,
Bose P
, Issa GC,
Ferrajoli A
,
Jabbour EJ
,
Jain N
,
Garcia-Manero G
,
Ohanian M
,
Takahashi K
, Montalban-Bravo G, Masarova L,
Burger JA
, Thompson PA,
Verstovsek S
, Sasaki K,
Andreeff M
, Rausch CR, Montalbano KS, Pierce S, Qiao W, Ning J,
Kantarjian HM
,
Konopleva MY
, Ravandi F. Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia. Blood Adv. 2021 04 13; 5(7):1876-1883.
PMID:
33792630
; PMCID:
PMC8045494
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Shah MV,
Saliba RM
, Varma A,
Ciurea SO
,
Oran B
,
Olson A
,
Bose P
,
Bashir Q
, Masarova L,
Alousi AM
, Srour S,
Mehta RS
,
Daver N
,
Pemmaraju N
,
Verstovsek S
,
Champlin RE
,
Popat UR
. Allogeneic stem cell transplant for patients with myeloproliferative neoplasms in blast phase: improving outcomes in the recent era. Br J Haematol. 2021 06; 193(5):1004-1008.
PMID:
33821472
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Pemmaraju N
, Wilson NR, Clementi Doan T, Qiao W, Peterson SK, Zoeller V, Schorr A,
Verstovsek S
. Myeloproliferative neoplasm questionnaire: assessing patient disease knowledge in the modern digital information era. Leuk Lymphoma. 2021 09; 62(9):2253-2260.
PMID:
33749512
; PMCID:
PMC9938727
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Rozovski U, Harris DM, Li P, Liu Z, Jain P, Manshouri T, Veletic I,
Ferrajoli A
,
Bose P
, Thompson P,
Jain N
,
Verstovsek S
,
Wierda W
, Keating MJ,
Estrov Z
. STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells. Oncotarget. 2021 Mar 02; 12(5):401-411.
PMID:
33747356
; PMCID:
PMC7939524
.
Citations:
3
Fields:
Neo
Neoplasms
Yacoub A, Lyons R,
Verstovsek S
, Shao R, Chu DT, Agrawal A, Sivaraman S, Colucci P, Paranagama D, Mascarenhas J. Disease and Clinical Characteristics of Patients With a Clinical Diagnosis of Essential Thrombocythemia Enrolled in the MOST Study. Clin Lymphoma Myeloma Leuk. 2021 07; 21(7):461-469.
PMID:
33839074
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Pemmaraju N
, Chen NC,
Verstovsek S
. Immunotherapy and Immunomodulation in Myeloproliferative Neoplasms. Hematol Oncol Clin North Am. 2021 04; 35(2):409-429.
PMID:
33641877
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Chen CC, Ellis M, Fox L, Goh YT, Gupta V, Harrison C, Lazaroiu MC, Mead A, McLornan D, McMullin MF, Platzbecker U, Vannucchi A, Yoon SS, Kowalski MM,
Verstovsek S
, Egyed M, Kiladjian JJ, Oh ST, Perkins A, Scheid C, Mesa RA. MOMENTUM: momelotinib vs danazol in patients with myelofibrosis previously treated with JAKi who are symptomatic and anemic. Future Oncol. 2021 Apr; 17(12):1449-1458.
PMID:
33423550
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L,
Bose P
,
Pemmaraju N
,
Daver N
, Zhou L, Pierce S,
Kantarjian H
,
Estrov Z
,
Verstovsek S
. Clinical Significance of Bone Marrow Blast Percentage in Patients With Myelofibrosis and the Effect of Ruxolitinib Therapy. Clin Lymphoma Myeloma Leuk. 2021 05; 21(5):318-327.e6.
PMID:
33551345
; PMCID:
PMC8849582
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Kucine N, Bergmann S, Krichevsky S, Jones D,
Rytting M
, Jain J, Bennett CM, Resar LMS, Mascarenhas J,
Verstovsek S
, Hoffman R. Use of pegylated interferon in young patients with polycythemia vera and essential thrombocythemia. Pediatr Blood Cancer. 2021 03; 68(3):e28888.
PMID:
33381905
; PMCID:
PMC9040312
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Ped
Pediatrics
Translation:
Humans
Tremblay D, Mesa R, Scott B, Buckley S, Roman-Torres K,
Verstovsek S
, Mascarenhas J. Pacritinib demonstrates spleen volume reduction in patients with myelofibrosis independent of JAK2V617F allele burden. Blood Adv. 2020 12 08; 4(23):5929-5935.
PMID:
33275766
; PMCID:
PMC7724916
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Assi R,
Kantarjian H
, Keating M,
Pemmaraju N
,
Verstovsek S
,
Garcia-Manero G
, Ravandi F,
Borthakur G
, Dahl J,
Jabbour E
,
Cortes JE
. Management of chronic myeloid leukemia during pregnancy among patients treated with a tyrosine kinase inhibitor: a single-Center experience. Leuk Lymphoma. 2021 04; 62(4):909-917.
PMID:
33283580
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Chifotides HT, Masarova L, Alfayez M,
Daver N
,
Alvarado Y
,
Jabbour E
,
Konopleva M
,
Kantarjian HM
,
Patel KP
,
DiNardo CD
,
Verstovsek S
. Outcome of patients with IDH1/2-mutated post-myeloproliferative neoplasm AML in the era of IDH inhibitors. Blood Adv. 2020 11 10; 4(21):5336-5342.
PMID:
33112940
; PMCID:
PMC7656917
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Fountain E, Cheng L, Masarova L,
Verstovsek S
, Rojas-Hernandez CM, Davila-Gonzalez D, Barrios-Ruiz A. Diagnostic Performance of Erythropoietin Levels in Polycythemia Vera: Experience at a Comprehensive Cancer Center. Clin Lymphoma Myeloma Leuk. 2021 04; 21(4):224-229.
PMID:
33349602
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Bose P
, Masarova L,
Verstovsek S
. Novel Concepts of Treatment for Patients with Myelofibrosis and Related Neoplasms. Cancers (Basel). 2020 Oct 09; 12(10).
PMID:
33050168
; PMCID:
PMC7599937
.
Citations:
3
Oh ST, Talpaz M, Gerds AT, Gupta V,
Verstovsek S
, Mesa R, Miller CB, Rivera CE, Fleischman AG, Goel S, Heaney ML, O'Connell C, Arcasoy MO, Zhang Y, Kawashima J, Ganz T, Kowalski M, Brachmann CB. ACVR1/JAK1/JAK2 inhibitor momelotinib reverses transfusion dependency and suppresses hepcidin in myelofibrosis phase 2 trial. Blood Adv. 2020 09 22; 4(18):4282-4291.
PMID:
32915978
; PMCID:
PMC7509854
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
DiNardo CD
, Maiti A, Rausch CR,
Pemmaraju N
,
Naqvi K
,
Daver NG
,
Kadia TM
,
Borthakur G
,
Ohanian M
,
Alvarado Y
, Issa GC, Montalban-Bravo G, Short NJ, Yilmaz M,
Bose P
,
Jabbour EJ
,
Takahashi K
,
Burger JA
,
Garcia-Manero G
,
Jain N
,
Kornblau SM
, Thompson PA,
Estrov Z
, Masarova L, Sasaki K,
Verstovsek S
,
Ferrajoli A
, Weirda WG, Wang SA,
Konoplev S
, Chen Z, Pierce SA,
Ning J
, Qiao W, Ravandi F,
Andreeff M
, Welch JS,
Kantarjian HM
,
Konopleva MY
. 10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial. Lancet Haematol. 2020 Oct; 7(10):e724-e736.
PMID:
32896301
; PMCID:
PMC7549397
.
Citations:
62
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Chifotides HT,
Verstovsek S
. New Therapies in Development for Myelofibrosis. Clin Lymphoma Myeloma Leuk. 2020 09; 20 Suppl 1:S69-S71.
PMID:
32862875
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Abaza Y,
Kantarjian H
, Alwash Y,
Borthakur G
,
Champlin R
,
Kadia T
,
Garcia-Manero G
,
Daver N
, Ravandi F,
Verstovsek S
,
Burger J
,
Estrov Z
,
Ohanian M
, Lim M,
Pemmaraju N
,
Jabbour E
, Cortes J. Phase I/II study of dasatinib in combination with decitabine in patients with accelerated or blast phase chronic myeloid leukemia. Am J Hematol. 2020 11; 95(11):1288-1295.
PMID:
32681739
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Masarova L,
Bose P
,
Pemmaraju N
,
Daver NG
, Zhou L, Pierce S, Sasaki K,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Prognostic value of blasts in peripheral blood in myelofibrosis in the ruxolitinib era. Cancer. 2020 10 01; 126(19):4322-4331.
PMID:
32697338
; PMCID:
PMC7875207
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Chifotides HT,
Bose P
,
Verstovsek S
. Givinostat: an emerging treatment for polycythemia vera. Expert Opin Investig Drugs. 2020 Jun; 29(6):525-536.
PMID:
32693648
; PMCID:
PMC7534842
.
Citations:
12
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Bose P
,
Verstovsek S
. JAK Inhibition for the Treatment of Myelofibrosis: Limitations and Future Perspectives. Hemasphere. 2020 Aug; 4(4):e424.
PMID:
32903304
; PMCID:
PMC7375176
.
Citations:
11
Paul S, Jammal N, Akhave N,
Aung PP
,
Loghavi S
,
Jain N
,
Garcia-Manero G
,
Borthakur G
,
Verstovsek S
,
Jabbour E
,
Adachi J
, Masarova L,
Daver N
, Ravandi F,
Pemmaraju N
. Atypical cases of necrotizing sweet syndrome in patients with myelodysplastic syndrome and acute myeloid leukaemia. Br J Haematol. 2020 10; 191(1):e10-e13.
PMID:
32686139
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Hu B, Lin X, Lee HC, Huang X, Tidwell RSS, Ahn KW, Hu ZH,
Jabbour E
,
Verstovsek S
, Ravandi F,
Garcia-Manero G
, Kharfan-Dabaja MA, Hossain NM, Marks DI, Kamble RT, Inamoto Y, Kindwall-Keller T, Saad A, Litzow MR, Savani BN, Hale GA, Bacher U, Gerds AT, Liesveld JL, Ustun C, Olsson RF, Daly A, Grunwald MR, Solh M, DeFilipp Z, Aljurf M, Wirk B, Akpek G, Nishihori T, Cerny J, Seo S, Hsu JW,
Champlin R
, de Lima M, Alyea E,
Popat U
, Sobecks R, Scott BL,
Kantarjian H
, Cortes J, Saber W. Timing of allogeneic hematopoietic cell transplantation (alloHCT) for chronic myeloid leukemia (CML) patients. Leuk Lymphoma. 2020 12; 61(12):2811-2820.
PMID:
32662346
; PMCID:
PMC8424781
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Jabbour E
, Richard-Carpentier G, Sasaki Y,
Konopleva M
, Patel K, Roberts K, Gu Z, Wang F, Huang X, Sasaki K, Short NJ,
Jain N
, Ravandi F,
Daver NG
,
Kadia TM
,
Alvarado Y
,
DiNardo CD
, Issa GC,
Pemmaraju N
,
Garcia-Manero G
,
Verstovsek S
, Wang S,
Khoury JD
,
Jorgensen J
,
Champlin R
,
Khouri I
,
Kebriaei P
, Schroeder H, Khouri M, Mullighan CG,
Takahashi K
, O'Brien SM,
Kantarjian H
. Hyper-CVAD regimen in combination with ofatumumab as frontline therapy for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia: a single-arm, phase 2 trial. Lancet Haematol. 2020 Jul; 7(7):e523-e533.
PMID:
32589978
.
Citations:
10
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Ohanian M
,
Kantarjian HM
, Shoukier M, Dellasala S, Musaelyan A, Nogueras Gonzalez GM,
Jabbour E
, Abruzzo L,
Verstovsek S
,
Borthakur G
, Ravandi F,
Garcia-Manero G
, Tamamyan G,
Champlin R
, Pierce S,
Ferrajoli A
,
Kadia T
,
Cortes JE
. The clinical impact of time to response in de novo accelerated-phase chronic myeloid leukemia. Am J Hematol. 2020 Jun 17.
PMID:
32557828
.
Citations:
1
Fields:
Hem
Hematology
Issa GC,
Kantarjian HM
, Xiao L,
Ning J
,
Alvarado Y
,
Borthakur G
,
Daver N
,
DiNardo CD
,
Jabbour E
,
Bose P
,
Jain N
,
Kadia TM
,
Naqvi K
,
Pemmaraju N
,
Takahashi K
,
Verstovsek S
, Andreeff M,
Kornblau SM
,
Estrov Z
,
Ferrajoli A
,
Garcia-Manero G
,
Ohanian M
,
Wierda WG
, Ravandi F,
Cortes JE
. Phase II trial of CPX-351 in patients with acute myeloid leukemia at high risk for induction mortality. Leukemia. 2020 11; 34(11):2914-2924.
PMID:
32546726
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Fang H, Tang G,
Loghavi S
, Greipp P, Wang W,
Verstovsek S
,
Medeiros LJ
, Reichard KK,
Miranda RN
, Wang SA. Systematic use of fluorescence in-situ hybridisation and clinicopathological features in the screening of PDGFRB rearrangements of patients with myeloid/lymphoid neoplasms. Histopathology. 2020 06; 76(7):1042-1054.
PMID:
32083752
.
Citations:
3
Fields:
Pat
Pathology
Translation:
Humans
Gowin K, Ballen K, Ahn KW, Hu ZH, Ali H, Arcasoy MO, Devlin R, Coakley M, Gerds AT, Green M, Gupta V, Hobbs G, Jain T, Kandarpa M, Komrokji R, Kuykendall AT, Luber K, Masarova L, Michaelis LC, Patches S, Pariser AC, Rampal R, Stein B, Talpaz M,
Verstovsek S
, Wadleigh M, Agrawal V, Aljurf M, Angel Diaz M, Avalos BR, Bacher U, Bashey A, Beitinjaneh AM, Cerny J, Chhabra S, Copelan E, Cutler CS, DeFilipp Z, Gadalla SM, Ganguly S, Grunwald MR, Hashmi SK, Kharfan-Dabaja MA, Kindwall-Keller T, Lazarus HM, Liesveld JL, Litzow MR, Marks DI, Nathan S, Nishihori T, Olsson RF, Pawarode A, Rowe JM, Savani BN, Savoie ML, Seo S, Solh M, Tamari R, Verdonck LF, Yared JA, Alyea E,
Popat U
, Sobecks R, Scott BL, Nakamura R, Mesa R, Saber W, Kr?ger N. Survival following allogeneic transplant in patients with myelofibrosis. Blood Adv. 2020 05 12; 4(9):1965-1973.
PMID:
32384540
; PMCID:
PMC7218417
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Paul S, Rausch CR,
Jain N
,
Kadia T
, Ravandi F,
DiNardo CD
, Welch MA,
Dabaja BS
,
Daver N
,
Garcia-Manero G
,
Wierda W
,
Pemmaraju N
, Montalban Bravo G, Thompson P,
Verstovsek S
,
Konopleva M
,
Kantarjian H
,
Jabbour E
. Treating Leukemia in the Time of COVID-19. Acta Haematol. 2021; 144(2):132-145.
PMID:
32392559
; PMCID:
PMC7270066
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
Cells
PH
Public Health
Popat U
,
Mehta RS
, Bassett R, Kongtim P, Chen J,
Alousi AM
,
Anderlini P
,
Ciurea S
,
Hosing C
, Jones R,
Kebriaei P
,
Khouri I
, Lindsay R,
Nieto Y
,
Olson A
,
Oran B
,
Qazilbash MH
,
Rondon G
,
Shpall EJ
,
Verstovsek S
,
Andersson BS
,
Champlin RE
. Optimizing the Conditioning Regimen for Hematopoietic Cell Transplant in Myelofibrosis: Long-Term Results of a Prospective Phase II Clinical Trial. Biol Blood Marrow Transplant. 2020 08; 26(8):1439-1445.
PMID:
32438043
; PMCID:
PMC7547798
.
Citations:
1
Fields:
Hem
Hematology
Tra
Transplantation
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Yu J, Kish JK, Paranagama D, Kaufman J, Myerscough C, Grunwald MR, Colucci P, Mesa R. Real-world risk assessment and treatment initiation among patients with myelofibrosis at community oncology practices in the United States. Ann Hematol. 2020 Nov; 99(11):2555-2564.
PMID:
32382773
; PMCID:
PMC7536164
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Maiti A,
Kantarjian HM
, Popat V,
Borthakur G
,
Garcia-Manero G
,
Konopleva MY
,
DiNardo CD
,
Verstovsek S
,
Andreeff M
,
Kadia TM
, Ajufo HO, Goswamy RV, Blanco C, Velasquez M,
Daver NG
,
Pemmaraju N
, Pierce SR,
Wierda WG
,
Kornblau SM
, Ravandi F,
Cortes JE
. Clinical value of event-free survival in acute myeloid leukemia. Blood Adv. 2020 04 28; 4(8):1690-1699.
PMID:
32330243
; PMCID:
PMC7189295
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Harrison CN, Schaap N, Vannucchi AM, Silver RT, Schouten HC, Passamonti F, Zweegman S, Talpaz M,
Verstovsek S
, Rose S, Shen J, Berry T, Brownstein C, Mesa RA, Kiladjian JJ, Jourdan E. Fedratinib in patients with myelofibrosis previously treated with ruxolitinib: An updated analysis of the JAKARTA2 study using stringent criteria for ruxolitinib failure. Am J Hematol. 2020 06; 95(6):594-603.
PMID:
32129512
; PMCID:
PMC7317815
.
Citations:
24
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Bose P
,
Verstovsek S
. Management of myelofibrosis after ruxolitinib failure. Leuk Lymphoma. 2020 08; 61(8):1797-1809.
PMID:
32297800
; PMCID:
PMC8565616
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Saenz DT,
Fiskus W
, Mill CP, Perera D, Manshouri T, Lara BH, Karkhanis V, Sharma S, Horrigan SK,
Bose P
,
Kadia TM
, Masarova L,
DiNardo CD
,
Borthakur G
,
Khoury JD
,
Takahashi K
, Bhaskara S, Lin CY, Green MR,
Coarfa C
, Crews CM,
Verstovsek S
,
Bhalla KN
. Mechanistic basis and efficacy of targeting the ?-catenin-TCF7L2-JMJD6-c-Myc axis to overcome resistance to BET inhibitors. Blood. 2020 04 09; 135(15):1255-1269.
PMID:
32068780
; PMCID:
PMC7146021
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Cells
Hu Z, Wang W,
Thakral B
, Chen Z,
Estrov Z
,
Bueso-Ramos CE
,
Verstovsek S
, Medeiros LJ, Wang SA. Lymphocytic variant of hypereosinophilic syndrome: A report of seven cases from a single institution. Cytometry B Clin Cytom. 2021 05; 100(3):352-360.
PMID:
32157815
.
Citations:
1
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Marcellino BK,
Verstovsek S
, Mascarenhas J. The Myelodepletive Phenotype in Myelofibrosis: Clinical Relevance and Therapeutic Implication. Clin Lymphoma Myeloma Leuk. 2020 07; 20(7):415-421.
PMID:
32199764
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Bose P
,
Verstovsek S
,
Cortes JE
, Tse S, Gasior Y,
Jain N
,
Jabbour EJ
,
Estrov Z
,
Alvarado Y
,
DiNardo CD
,
Pemmaraju N
,
Kornblau SM
,
Kadia TM
,
Daver NG
,
Naqvi K
, Short NJ, Masarova L, Villareal J, Pierce SA, Nogueras-Gonzalez G, Huang X,
Garcia-Manero G
,
Kantarjian HM
, Ravandi F. A phase 1/2 study of ruxolitinib and decitabine in patients with post-myeloproliferative neoplasm acute myeloid leukemia. Leukemia. 2020 09; 34(9):2489-2492.
PMID:
32099037
.
Citations:
13
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Lopez-Mattei J
,
Verstovsek S
, Fellman B,
Iliescu C
, Bhatti K,
Hassan SA
, Kim P, Gray BA, Palaskas NL,
Grosu HB
, Mamas MA,
Faiz SA
. Prevalence of pulmonary hypertension in myelofibrosis. Ann Hematol. 2020 Apr; 99(4):781-789.
PMID:
32076825
; PMCID:
PMC9225959
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Maiti A,
Cortes JE
,
Patel KP
, Masarova L,
Borthakur G
, Ravandi F,
Verstovsek S
,
Ferrajoli A
,
Estrov Z
,
Garcia-Manero G
,
Kadia TM
, Skinner J, Poku R, DellaSala S,
Luthra R
,
Jabbour EJ
, O'Brien S,
Kantarjian HM
, Nogueras-Gonz?lez GM. Long-term results of frontline dasatinib in chronic myeloid leukemia. Cancer. 2020 04 01; 126(7):1502-1511.
PMID:
31999839
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L,
Cortes JE
,
Patel KP
, O'Brien S, Nogueras-Gonzalez GM,
Konopleva M
,
Verstovsek S
,
Garcia-Manero G
,
Ferrajoli A
,
Kadia TM
,
Ravandi-Kashani F
,
Borthakur G
, DellaSala S,
Estrov Z
,
Jabbour EJ
,
Kantarjian HM
. Long-term results of a phase 2 trial of nilotinib 400?mg twice daily in newly diagnosed patients with chronic-phase chronic myeloid leukemia. Cancer. 2020 04 01; 126(7):1448-1459.
PMID:
31999850
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Zachee P, Hino M, Pane F, Masszi T, Harrison CN, Mesa R, Miller CB, Passamonti F, Durrant S, Griesshammer M, Kirito K, Moiraghi B, Rumi E, Rosti V, Francillard N, Dong T, Wroclawska M, Vannucchi AM,
Verstovsek S
, Kiladjian JJ, Besses C, Blau IW. Long-term efficacy and safety of ruxolitinib versus best available therapy in polycythaemia vera (RESPONSE): 5-year follow up of a phase 3 study. Lancet Haematol. 2020 Mar; 7(3):e226-e237.
PMID:
31982039
; PMCID:
PMC8938906
.
Citations:
27
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Fuentes-Mattei E
, Bayraktar R, Manshouri T, Silva AM,
Ivan C
, Gulei D, Fabris L, Soares do Amaral N, Mur P, Perez C, Torres-Claudio E, Dragomir MP, Badillo-Perez A, Knutsen E, Narayanan P, Golfman L, Shimizu M, Zhang X, Zhao W, Ho WT, Estecio MR,
Bartholomeusz G
, Tomuleasa C, Berindan-Neagoe I, Zweidler-McKay PA,
Estrov Z
, Zhao ZJ,
Verstovsek S
,
Calin GA
, Redis RS. miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2. JCI Insight. 2020 01 16; 5(1).
PMID:
31941838
; PMCID:
PMC7030823
.
Citations:
9
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Ye MT, Wang Y, Wang SA,
Pemmaraju N
,
Daver N
,
Verstovsek S
, Zhang Y,
Zuo Z
,
Medeiros LJ
, You MJ. Concurrent JAK2 V617F and MPL W515L in myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis. Leuk Lymphoma. 2020 04; 61(4):963-966.
PMID:
31750750
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Yilmaz M,
Kantarjian H
, Wang X,
Khoury JD
, Ravandi F,
Jorgensen J
, Short NJ,
Loghavi S
, Cortes J,
Garcia-Manero G
,
Kadia T
, Sasaki K,
Konopleva M
,
Takahashi K
,
Wierda W
,
Jain N
,
Verstovsek S
,
Estrov Z
,
Bose P
, Pierce S, Garris R, O'Brien S,
Jabbour E
. The early achievement of measurable residual disease negativity in the treatment of adults with Philadelphia-negative B-cell acute lymphoblastic leukemia is a strong predictor for survival. Am J Hematol. 2020 02; 95(2):144-150.
PMID:
31682008
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Bose P
,
Verstovsek S
. Mutational profiling in myelofibrosis: implications for management. Int J Hematol. 2020 Feb; 111(2):192-199.
PMID:
31630335
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Getta B, Masarova L, Famulare C, Schulman J, Arcila ME,
Kantarjian HM
, Levine RL, Rampal RK,
Verstovsek S
, Santos FPS, Datoguia TS, Puga RD, Alves Paiva RM, Hamerschlak N, Campregher PV. Prognostic impact of RAS-pathway mutations in patients with myelofibrosis. Leukemia. 2020 03; 34(3):799-810.
PMID:
31628430
; PMCID:
PMC7158221
.
Citations:
16
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Economides MP,
Verstovsek S
,
Pemmaraju N
. Novel Therapies in Myeloproliferative Neoplasms (MPN): Beyond JAK Inhibitors. Curr Hematol Malig Rep. 2019 10; 14(5):460-468.
PMID:
31372878
.
Citations:
11
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Manshouri T,
Verstovsek S
, Harris DM, Veletic I, Zhang X,
Post SM
,
Bueso-Ramos CE
,
Estrov Z
. Primary myelofibrosis marrow-derived CD14+/CD34- monocytes induce myelofibrosis-like phenotype in immunodeficient mice and give rise to megakaryocytes. PLoS One. 2019; 14(9):e0222912.
PMID:
31569199
; PMCID:
PMC6768666
.
Citations:
6
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Abou Dalle I,
Kantarjian H
,
Burger J
,
Estrov Z
,
Ohanian M
,
Verstovsek S
, Ravandi F,
Borthakur G
,
Garcia-Manero G
,
Jabbour E
, Cortes J. Efficacy and safety of generic imatinib after switching from original imatinib in patients treated for chronic myeloid leukemia in the United States. Cancer Med. 2019 11; 8(15):6559-6565.
PMID:
31502383
; PMCID:
PMC6825993
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Bose P
,
Verstovsek S
. Updates in the management of polycythemia vera and essential thrombocythemia. Ther Adv Hematol. 2019; 10:2040620719870052.
PMID:
31516686
; PMCID:
PMC6719465
.
Citations:
10
Gotlib J, Baird JH, George TI, Langford C, Reyes I, Abuel J, Perkins C, Schroeder K,
Bose P
,
Verstovsek S
. A phase 2 study of brentuximab vedotin in patients with CD30-positive advanced systemic mastocytosis. Blood Adv. 2019 08 13; 3(15):2264-2271.
PMID:
31350306
; PMCID:
PMC6693006
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Masarova L,
Bose P
,
Verstovsek S
. The Rationale for Immunotherapy in Myeloproliferative Neoplasms. Curr Hematol Malig Rep. 2019 08; 14(4):310-327.
PMID:
31228096
.
Citations:
12
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Bose P
,
Verstovsek S
. MF management. Hemasphere. 2019 Jun; 3(Suppl).
PMID:
35309812
; PMCID:
PMC8925717
.
Citations:
1
Mughal TI,
Pemmaraju N
, Radich JP, Deininger MW, Kucine N, Kiladjian JJ,
Bose P
, Gotlib J, Valent P, Chen CC, Barbui T, Rampal R,
Verstovsek S
, Koschmieder S, Saglio G, Van Etten RA. Emerging translational science discoveries, clonal approaches, and treatment trends in chronic myeloproliferative neoplasms. Hematol Oncol. 2019 Aug; 37(3):240-252.
PMID:
31013548
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Boddu P, Jain P,
Borthakur G
,
Verstovsek S
,
Garcia-Manero G
,
Daver N
,
Kadia T
, Ravandi F,
Jabbour E
, Cortes J,
Kantarjian H
. Outcomes of patients with chronic phase chronic myeloid leukemia (CML-CP) after discontinuation of frontline ponatinib therapy. Leuk Lymphoma. 2019 12; 60(13):3172-3180.
PMID:
31125272
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Strati P, Abdelrahim M, Selamet U, Page VD, Pierce SA,
Verstovsek S
,
Abudayyeh A
. Ruxolitinib therapy is associated with improved renal function in patients with primary myelofibrosis. Ann Hematol. 2019 Jul; 98(7):1611-1616.
PMID:
31093708
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Masarova L,
Verstovsek S
. Emerging drugs for essential thrombocythemia. Expert Opin Emerg Drugs. 2019 06; 24(2):93-105.
PMID:
31050912
.
Citations:
Fields:
Dru
Drug Therapy
Translation:
Humans
Masarova L,
Verstovsek S
. The evolving understanding of prognosis in post-essential thrombocythemia myelofibrosis and post-polycythemia vera myelofibrosis vs primary myelofibrosis. Clin Adv Hematol Oncol. 2019 May; 17(5):299-307.
PMID:
31188809
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Jain P,
Kantarjian H
, Boddu PC,
Verstovsek S
,
Garcia-Manero G
,
Borthakur G
, Sasaki K,
Kadia TM
, Sam P, Ahaneku H, O'Brien S,
Estrov Z
, Ravandi F,
Jabbour E
,
Cortes JE
, Nogueras-Gonz?lez GM. Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs. Blood Adv. 2019 03 26; 3(6):851-861.
PMID:
30885996
; PMCID:
PMC6436011
.
Citations:
29
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Pettit K,
Verstovsek S
, Talpaz M. SOHO State of the Art Updates and Next Questions: Myelofibrosis. Clin Lymphoma Myeloma Leuk. 2019 04; 19(4):191-199.
PMID:
30987952
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Boddu P,
Carter BZ
,
Verstovsek S
,
Pemmaraju N
. SMAC mimetics as potential cancer therapeutics in myeloid malignancies. Br J Haematol. 2019 04; 185(2):219-231.
PMID:
30836448
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Benton CB
, Boddu PC,
DiNardo CD
,
Bose P
, Wang F, Assi R,
Pemmaraju N
, Kc D, Pierce S, Patel K,
Konopleva M
, Ravandi F,
Garcia-Manero G
,
Kadia TM
, Cortes J,
Kantarjian HM
,
Andreeff M
,
Verstovsek S
. Janus kinase 2 variants associated with the transformation of myeloproliferative neoplasms into acute myeloid leukemia. Cancer. 2019 06 01; 125(11):1855-1866.
PMID:
30811597
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Pemmaraju N
,
Kantarjian H
,
Nastoupil L
, Dupuis M, Zhou L, Pierce S,
Patel KP
, Masarova L, Cortes J,
Verstovsek S
. Characteristics of patients with myeloproliferative neoplasms with lymphoma, with or without JAK inhibitor therapy. Blood. 2019 05 23; 133(21):2348-2351.
PMID:
30796023
; PMCID:
PMC6634962
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Veletic I, Manshouri T,
Multani AS
, Yin CC, Chen L,
Verstovsek S
,
Estrov Z
. Myelofibrosis osteoclasts are clonal and functionally impaired. Blood. 2019 05 23; 133(21):2320-2324.
PMID:
30745304
; PMCID:
PMC6533604
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Cells
Bose P
, Alfayez M,
Verstovsek S
. New Concepts of Treatment for Patients with Myelofibrosis. Curr Treat Options Oncol. 2019 01 24; 20(1):5.
PMID:
30675650
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Bose P
, Swaminathan M,
Pemmaraju N
,
Ferrajoli A
,
Jabbour EJ
,
Daver NG
,
DiNardo CD
,
Alvarado Y
, Yilmaz M, Huynh-Lu J, Qiao W, Wang X, Matamoros A, Zhou L, Pierce S, Schroeder KD,
Kantarjian HM
,
Verstovsek S
. A phase 2 study of pracinostat combined with ruxolitinib in patients with myelofibrosis. Leuk Lymphoma. 2019 07; 60(7):1767-1774.
PMID:
30632841
; PMCID:
PMC6594864
.
Citations:
8
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Bose P
, Masarova L,
Verstovsek S
. Novel treatment strategies for myeloproliferative neoplasms. Rinsho Ketsueki. 2019; 60(9):1176-1185.
PMID:
31597841
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Saenz DT,
Fiskus W
, Manshouri T, Mill CP, Qian Y, Raina K, Rajapakshe K,
Coarfa C
,
Bose P
,
Borthakur G
,
Kadia TM
,
Khoury JD
, Masarova L, Nowak AJ, Sun B, Saenz DN,
Kornblau SM
, Sharma S, Qiu P, Crews CM,
Verstovsek S
,
Bhalla KN
, Soldi R, Horrigan S. Targeting nuclear ?-catenin as therapy for post-myeloproliferative neoplasm secondary AML. Leukemia. 2019 06; 33(6):1373-1386.
PMID:
30575820
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Swaminathan M,
Patel KP
, Huynh-Lu J, Tang G,
Zuo Z
,
Miranda R
,
Verstovsek S
. Unique Case of Myeloproliferative Neoplasm with Two Rare Clonal Abnormalities: Rare JAK2 Exon 12 Mutation and Rare e14a3 (b3a3) BCR/ABL Fusion Transcript. Acta Haematol. 2019; 141(1):23-27.
PMID:
30463063
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Hu Z, Ramos CEB, Medeiros LJ, Zhao C, Yin CC, Li S, Hu S, Wang W,
Thakral B
, Xu J,
Verstovsek S
, Lin P. Utility of JAK2 V617F allelic burden in distinguishing chronic myelomonocytic Leukemia from Primary myelofibrosis with monocytosis. Hum Pathol. 2019 03; 85:290-298.
PMID:
30447300
.
Citations:
7
Fields:
Pat
Pathology
Translation:
Humans
Cells
Masarova L,
Verstovsek S
. Therapeutic Approach to Young Patients With Low-Risk Essential Thrombocythemia: Primum Non Nocere. J Clin Oncol. 2018 Oct 22; JCO2018793497.
PMID:
30346901
.
Citations:
1
Fields:
Neo
Neoplasms
Hu Z, Boddu PC,
Loghavi S
,
Miranda RN
, Goswami M, Medeiros LJ, Tam W, Orazi A,
Verstovsek S
, Wang SA. A multimodality work-up of patients with Hypereosinophilia. Am J Hematol. 2018 11; 93(11):1337-1346.
PMID:
30105844
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Couban S, Donnellan W, Cultrera J,
Verstovsek S
, Hooper G, Hertig C, Tandon M, Dimier N, Malhi V, Benevolo G, Koschmieder S, Passamonti F. A phase Ib study to assess the efficacy and safety of vismodegib in combination with ruxolitinib in patients with intermediate- or high-risk myelofibrosis. J Hematol Oncol. 2018 09 24; 11(1):122.
PMID:
30249277
; PMCID:
PMC6154811
.
Citations:
15
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Bose P
, Nazha A, Komrokji RS,
Patel KP
, Pierce SA, Al-Ali N, Sochacki A, Shaver A, Ma W,
Su X
,
Daver NG
,
DiNardo CD
,
Garcia-Manero G
,
Loghavi S
,
Bueso-Ramos C
,
Kantarjian HM
, Sekeres MA, Savona MR, Maciejewski JP,
Verstovsek S
. Mutational landscape of myelodysplastic/myeloproliferative neoplasm-unclassifiable. Blood. 2018 11 08; 132(19):2100-2103.
PMID:
30242087
; PMCID:
PMC6236463
.
Citations:
17
Fields:
Hem
Hematology
Translation:
Humans
Abaza Y, Hidalgo-Lopez JE,
Verstovsek S
,
Jabbour E
, Ravandi F,
Borthakur G
,
Estrov Z
,
Alvarado Y
, Burger J, Schneider H, Soltysiak KA, Wei Y,
Kantarjian HM
,
Bueso-Ramos CE
,
Garcia-Manero G
. Phase I study of ruxolitinib in previously treated patients with low or intermediate-1 risk myelodysplastic syndrome with evidence of NF-kB activation. Leuk Res. 2018 10; 73:78-85.
PMID:
30245189
; PMCID:
PMC6750211
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Yeleswaram S, Hou K, Chen X, Erickson-Viitanen S. Sustained-release ruxolitinib: Findings from a phase 1 study in healthy subjects and a phase 2 study in patients with myelofibrosis. Hematol Oncol. 2018 Oct; 36(4):701-708.
PMID:
30105794
; PMCID:
PMC6221065
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L,
Verstovsek S
, Hidalgo-Lopez JE,
Pemmaraju N
,
Bose P
,
Estrov Z
,
Jabbour EJ
,
Ravandi-Kashani F
,
Takahashi K
,
Cortes JE
, Ning J,
Ohanian M
,
Alvarado Y
, Zhou L, Pierce S, Gergis R,
Patel KP
,
Luthra R
,
Kadia TM
,
DiNardo CD
,
Borthakur G
,
Bhalla K
,
Garcia-Manero G
,
Bueso-Ramos CE
,
Kantarjian HM
,
Daver N
. A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis. Blood. 2018 10 18; 132(16):1664-1674.
PMID:
30185431
; PMCID:
PMC6265645
.
Citations:
28
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kadia TM
, Cortes J, Ravandi F,
Jabbour E
,
Konopleva M
,
Benton CB
,
Burger J
, Sasaki K,
Borthakur G
,
DiNardo CD
,
Pemmaraju N
,
Daver N
,
Ferrajoli A
, Wang X, Patel K,
Jorgensen JL
, Wang S, O'Brien S, Pierce S, Tuttle C,
Estrov Z
,
Verstovsek S
,
Garcia-Manero G
,
Kantarjian H
. Cladribine and low-dose cytarabine alternating with decitabine as front-line therapy for elderly patients with acute myeloid leukaemia: a phase 2 single-arm trial. Lancet Haematol. 2018 Sep; 5(9):e411-e421.
PMID:
30115541
; PMCID:
PMC6775639
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Veletic I, Manshouri T, Newberry KJ, Garnett J,
Verstovsek S
,
Estrov Z
. Pentraxin-3 plasma levels correlate with tumour burden and overall survival in patients with primary myelofibrosis. Br J Haematol. 2019 04; 185(2):382-386.
PMID:
30074241
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Mughal TI, Lion T, Abdel-Wahab O, Mesa R, Scherber RM, Perrotti D, Mauro M,
Verstovsek S
, Saglio G, Van Etten RA, Kralovics R. Precision immunotherapy, mutational landscape, and emerging tools to optimize clinical outcomes in patients with classical myeloproliferative neoplasms. Hematol Oncol. 2018 Dec; 36(5):740-748.
PMID:
30074634
; PMCID:
PMC6613211
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Jennings SV, Slee VM, Zack RM,
Verstovsek S
, George TI, Shi H, Lee P, Castells MC. Patient Perceptions in Mast Cell Disorders. Immunol Allergy Clin North Am. 2018 08; 38(3):505-525.
PMID:
30007467
.
Citations:
5
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Verstovsek S
, Subbiah V, Masarova L, Yin CC, Tang G, Manshouri T, Asatiani E, Daver NG. Treatment of the myeloid/lymphoid neoplasm with FGFR1 rearrangement with FGFR1 inhibitor. Ann Oncol. 2018 08 01; 29(8):1880-1882.
PMID:
29767670
; PMCID:
PMC6887683
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Strati P, Glass WF, Abdelrahim M, Selamet U, Tchakarov A,
Workeneh BT
,
Verstovsek S
,
Abudayyeh A
. Renal complications of primary myelofibrosis. Leuk Lymphoma. 2019 02; 60(2):507-510.
PMID:
29966471
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Boddu P, Chihara D, Masarova L,
Pemmaraju N
,
Patel KP
,
Verstovsek S
. The co-occurrence of driver mutations in chronic myeloproliferative neoplasms. Ann Hematol. 2018 Nov; 97(11):2071-2080.
PMID:
29951914
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Cells
Falchi L,
Verstovsek S
. Kit Mutations: New Insights and Diagnostic Value. Immunol Allergy Clin North Am. 2018 08; 38(3):411-428.
PMID:
30007460
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Bose P
,
Verstovsek S
. Management of Myelofibrosis-Related Cytopenias. Curr Hematol Malig Rep. 2018 06; 13(3):164-172.
PMID:
29796726
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ohanian M
, Rozovski U, Kanagal-Shamanna R, Abruzzo LV,
Loghavi S
,
Kadia T
,
Futreal A
,
Bhalla K
,
Zuo Z
,
Huh YO
,
Post SM
,
Ruvolo P
,
Garcia-Manero G
,
Andreeff M
,
Kornblau S
,
Borthakur G
,
Hu P
,
Medeiros LJ
,
Takahashi K
, Hornbaker MJ, Zhang J, Huang X,
Verstovsek S
,
Estrov Z
, Pierce S, Ravandi F,
Kantarjian HM
,
Bueso-Ramos CE
,
Cortes JE
, Nogueras-Gonz?lez GM. MYC protein expression is an important prognostic factor in acute myeloid leukemia. Leuk Lymphoma. 2019 01; 60(1):37-48.
PMID:
29741984
; PMCID:
PMC6226369
.
Citations:
27
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Mascarenhas J, Hoffman R, Talpaz M, Gerds AT, Stein B, Gupta V, Drummond M, Pristupa A, Granston T, Daly R, Al-Fayoumi S, Callahan JA, Singer JW, Gotlib J, Jamieson C, Harrison C, Mesa R,
Verstovsek S
, Szoke A. Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial. JAMA Oncol. 2018 05 01; 4(5):652-659.
PMID:
29522138
; PMCID:
PMC5885169
.
Citations:
78
Fields:
Neo
Neoplasms
Translation:
Humans
Shah MY, Ferracin M, Pileczki V, Chen B, Redis R, Fabris L, Zhang X,
Ivan C
, Shimizu M, Rodriguez-Aguayo C, Dragomir M,
Van Roosbroeck K
, Almeida MI, Ciccone M, Nedelcu D,
Cortez MA
, Manshouri T, Calin S, Muftuoglu M, Banerjee PP, Badiwi MH,
Parker-Thornburg J
,
Multani A
,
Welsh JW
,
Estecio MR
,
Ling H
, Tomuleasa C, Dima D, Yang H, Alvarez H, You MJ, Radovich M,
Shpall E
, Fabbri M,
Rezvani K
, Girnita L, Berindan-Neagoe I,
Maitra A
,
Verstovsek S
, Fodde R,
Bueso-Ramos C
, Gagea M, Manero GG,
Calin GA
. Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations. Genome Res. 2018 04; 28(4):432-447.
PMID:
29567676
; PMCID:
PMC5880235
.
Citations:
32
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Khan M,
Muzzafar T
,
Kantarjian H
, Badar I, Short N, Wang X, Chamoun K, Jain P,
DiNardo C
,
Pemmaraju N
,
Bose P
,
Borthakur G
, Cortes J,
Verstovsek S
,
Garcia-Manero G
,
Estrov Z
. Association of bone marrow fibrosis with inferior survival outcomes in chronic myelomonocytic leukemia. Ann Hematol. 2018 Jul; 97(7):1183-1191.
PMID:
29557496
; PMCID:
PMC6506234
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Cells
Kvasnicka HM,
Bueso-Ramos CE
, Sun W, Cortes J,
Kantarjian HM
,
Verstovsek S
, Thiele J. Long-term effects of ruxolitinib versus best available therapy on bone marrow fibrosis in patients with myelofibrosis. J Hematol Oncol. 2018 03 15; 11(1):42.
PMID:
29544547
; PMCID:
PMC5856218
.
Citations:
36
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ohanian M
, Tari Ashizawa A,
Garcia-Manero G
,
Pemmaraju N
,
Kadia T
,
Jabbour E
, Ravandi F,
Borthakur G
,
Andreeff M
,
Konopleva M
, Lim M, Pierce S, O'Brien S,
Alvarado Y
,
Verstovsek S
,
Wierda W
,
Kantarjian H
, Cortes J. Liposomal Grb2 antisense oligodeoxynucleotide (BP1001) in patients with refractory or relapsed haematological malignancies: a single-centre, open-label, dose-escalation, phase 1/1b trial. Lancet Haematol. 2018 Apr; 5(4):e136-e146.
PMID:
29550383
.
Citations:
20
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Barbui T, Tefferi A, Vannucchi AM, Passamonti F, Silver RT, Hoffman R,
Verstovsek S
, Mesa R, Hehlmann R, Reiter A, Harrison C, Mc Mullin MF, Hasselbalch HC, Koschmieder S, Marchetti M, Finazzi G, Kroeger N, Griesshammer M, Birgegard G, Barosi G, Kiladjian JJ, Cervantes F, Bacigalupo A. Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet. Leukemia. 2018 05; 32(5):1057-1069.
PMID:
29515238
; PMCID:
PMC5986069
.
Citations:
120
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Guglielmelli P, Griesshammer M, Saydam G, Durrant S, Passamonti F, Jones M, Zhen H, Li J, Gadbaw B, Perez Ronco J, Khan M,
Verstovsek S
, Kiladjian JJ, Masszi T. Efficacy and safety of ruxolitinib after and versus interferon use in the RESPONSE studies. Ann Hematol. 2018 Apr; 97(4):617-627.
PMID:
29396713
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Verstovsek S
. Highlights in myeloproliferative neoplasms from the 2017 American Society of Hematology Annual Meeting: commentary. Clin Adv Hematol Oncol. 2018 Feb; 16 Suppl 4(2):20-23.
PMID:
29742090
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Masarova L, Alhuraiji A,
Bose P
,
Daver N
,
Pemmaraju N
, Cortes J, Pierce S,
Kantarjian H
,
Verstovsek S
. Significance of thrombocytopenia in patients with primary and postessential thrombocythemia/polycythemia vera myelofibrosis. Eur J Haematol. 2018 Mar; 100(3):257-263.
PMID:
29226426
; PMCID:
PMC5814342
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Bose P
, Gotlib J, Harrison CN,
Verstovsek S
. SOHO State-of-the-Art Update and Next Questions: MPN. Clin Lymphoma Myeloma Leuk. 2018 01; 18(1):1-12.
PMID:
29277359
; PMCID:
PMC5915302
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Carballo-Zarate A,
Verstovsek S
, Wang SA, Hu S, Li S, Xu J, Zuo W,
Tang Z
, Yin CC,
Medeiros LJ
,
Bueso-Ramos CE
, Tang G, Hidalgo L?pez JE. Bone marrow findings in blast phase of polycythemia vera. Ann Hematol. 2018 Mar; 97(3):425-434.
PMID:
29285580
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Harrison CN, Vannucchi AM, Cervantes F, Gupta V, Lavie D, Passamonti F, Winton EF, Dong H, Kawashima J, Maltzman JD, Kiladjian JJ,
Verstovsek S
, Platzbecker U. Momelotinib versus best available therapy in patients with myelofibrosis previously treated with ruxolitinib (SIMPLIFY 2): a randomised, open-label, phase 3 trial. Lancet Haematol. 2018 Feb; 5(2):e73-e81.
PMID:
29275119
.
Citations:
70
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Shah MV,
Patel KP
, Luthra R, Kanagal-Shamanna R, Mehrotra M, Bachegowda LS,
Champlin RE
,
Verstovsek S
,
Popat UR
. Sensitive PCR-based monitoring and early detection of relapsed JAK2 V617F myelofibrosis following transplantation. Br J Haematol. 2018 12; 183(5):831-835.
PMID:
29265180
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Alhuraiji A,
Naqvi K
,
Huh YO
, Ho C,
Verstovsek S
,
Bose P
. Acute lymphoblastic leukemia secondary to myeloproliferative neoplasms or after lenalidomide exposure. Clin Case Rep. 2018 01; 6(1):155-161.
PMID:
29375856
; PMCID:
PMC5771935
.
Citations:
5
Stein BL,
Verstovsek S
. Prognostication and Initiation of Therapy in Polycythemia Vera: Do We Have it Right? Curr Hematol Malig Rep. 2017 12; 12(6):507-509.
PMID:
29032412
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Assi R,
Kantarjian HM
,
Garcia-Manero G
,
Cortes JE
,
Pemmaraju N
, Wang X, Nogueras-Gonzalez G,
Jabbour E
,
Bose P
,
Kadia T
,
Dinardo CD
, Patel K,
Bueso-Ramos C
, Zhou L, Pierce S, Gergis R, Tuttle C,
Borthakur G
,
Estrov Z
,
Luthra R
, Hidalgo-Lopez J,
Verstovsek S
,
Daver N
. A phase II trial of ruxolitinib in combination with azacytidine in myelodysplastic syndrome/myeloproliferative neoplasms. Am J Hematol. 2018 02; 93(2):277-285.
PMID:
29134664
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Boddu P, Masarova L,
Verstovsek S
, Strati P,
Kantarjian H
, Cortes J,
Estrov Z
, Pierce S,
Pemmaraju N
. Patient characteristics and outcomes in adolescents and young adults with classical Philadelphia chromosome-negative myeloproliferative neoplasms. Ann Hematol. 2018 Jan; 97(1):109-121.
PMID:
29143068
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Masarova L, Yin CC,
Cortes JE
,
Konopleva M
,
Borthakur G
, Newberry KJ,
Kantarjian HM
,
Bueso-Ramos CE
,
Verstovsek S
. Histomorphological responses after therapy with pegylated interferon a-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV). Exp Hematol Oncol. 2017; 6:30.
PMID:
29152412
; PMCID:
PMC5679503
.
Citations:
11
Alhuraiji A,
Kantarjian H
, Boddu P, Ravandi F,
Borthakur G
,
DiNardo C
,
Daver N
,
Kadia T
,
Pemmaraju N
, Pierce S,
Garcia-Manero G
,
Wierda W
,
Verstovsek S
,
Jabbour E
, Cortes J. Prognostic significance of additional chromosomal abnormalities at the time of diagnosis in patients with chronic myeloid leukemia treated with frontline tyrosine kinase inhibitors. Am J Hematol. 2018 01; 93(1):84-90.
PMID:
29027261
.
Citations:
14
Fields:
Hem
Hematology
Translation:
Humans
Strati P, Tang G, Duose DY,
Mallampati S
,
Luthra R
,
Patel KP
, Hussaini M, Mirza AS, Komrokji RS, Oh S, Mascarenhas J, Najfeld V,
Subbiah V
,
Kantarjian H
,
Garcia-Manero G
,
Verstovsek S
,
Daver N
. Myeloid/lymphoid neoplasms with FGFR1 rearrangement. Leuk Lymphoma. 2018 07; 59(7):1672-1676.
PMID:
29119847
.
Citations:
12
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Bose P
,
Verstovsek S
. Ruxolitinib for essential thrombocythemia? Oncoscience. 2017 Nov; 4(11-12):148-149.
PMID:
29344542
; PMCID:
PMC5769968
.
Citations:
1
Strati P,
Benton CB
, Manshouri T, Zhang Y, Bove JE, Sanchez-Petitto G,
Verstovsek S
. JAK2V617F detection and allele burden measurement in saliva vs. peripheral blood in patients with myelofibrosis. Leuk Res. 2017 12; 63:53-55.
PMID:
29101828
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
,
Fiskus W
, Manshouri T,
Bhalla KN
. Targeting cistrome and dysregulated transcriptome of post-MPN sAML. Oncotarget. 2017 Nov 07; 8(55):93301-93302.
PMID:
29212143
; PMCID:
PMC5706789
.
Citations:
5
Fields:
Neo
Neoplasms
Boddu P, Shah AR,
Borthakur G
,
Verstovsek S
,
Garcia-Manero G
,
Daver N
,
Kadia T
, Ravandi F,
Jain N
, Alhuraiji A,
Burger J
,
Kornblau S
, Pierce S, Dellasala S,
Jabbour E
,
Kantarjian H
, Cortes J. Life after ponatinib failure: outcomes of chronic and accelerated phase CML patients who discontinued ponatinib in the salvage setting. Leuk Lymphoma. 2018 06; 59(6):1312-1322.
PMID:
28972430
; PMCID:
PMC6120342
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Mesa RA, Jamieson C, Bhatia R, Deininger MW, Fletcher CD, Gerds AT, Gojo I, Gotlib J, Gundabolu K, Hobbs G, McMahon B, Mohan SR, Oh S, Padron E, Papadantonakis N, Pancari P, Podoltsev N, Rampal R, Ranheim E, Reddy V, Rein LAM, Scott B, Snyder DS, Stein BL, Talpaz M,
Verstovsek S
, Wadleigh M, Wang ES, Bergman MA, Gregory KM, Sundar H. NCCN Guidelines Insights: Myeloproliferative Neoplasms, Version 2.2018. J Natl Compr Canc Netw. 2017 10; 15(10):1193-1207.
PMID:
28982745
.
Citations:
41
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Gotlib J, Mesa RA, Vannucchi AM, Harrison CN, Paquette R, Sun W, Naim A, Langmuir P, Dong T, Gopalakrishna P, Gupta V, Kiladjian JJ, Cervantes F. Long-term survival in patients treated with ruxolitinib for myelofibrosis: COMFORT-I and -II pooled analyses. J Hematol Oncol. 2017 09 29; 10(1):156.
PMID:
28962635
; PMCID:
PMC5622445
.
Citations:
88
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Mesa RA, Salama ME, Li L, Pitou C, Nunes FP, Price GL, Giles JL, D'Souza DN, Walgren RA, Prchal JT. A phase 1 study of the Janus kinase 2 (JAK2)V617F inhibitor, gandotinib (LY2784544), in patients with primary myelofibrosis, polycythemia vera, and essential thrombocythemia. Leuk Res. 2017 10; 61:89-95.
PMID:
28934680
; PMCID:
PMC8207330
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L,
Verstovsek S
,
Kantarjian H
,
Daver N
. Immunotherapy based approaches in myelofibrosis. Expert Rev Hematol. 2017 10; 10(10):903-914.
PMID:
28799436
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
Verstovsek S
, Passamonti F, Rambaldi A, Barosi G, Rumi E, Gattoni E, Pieri L, Zhen H, Granier M, Assad A, Cazzola M,
Kantarjian HM
, Barbui T, Vannucchi AM. Ruxolitinib for essential thrombocythemia refractory to or intolerant of hydroxyurea: long-term phase 2 study results. Blood. 2017 10 12; 130(15):1768-1771.
PMID:
28827411
; PMCID:
PMC5639482
.
Citations:
24
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kc D, Falchi L,
Verstovsek S
. The underappreciated risk of thrombosis and bleeding in patients with myelofibrosis: a review. Ann Hematol. 2017 Oct; 96(10):1595-1604.
PMID:
28808761
; PMCID:
PMC5693670
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Jain P,
Kantarjian HM
, Ghorab A, Sasaki K,
Jabbour EJ
, Nogueras Gonzalez G, Kanagal-Shamanna R, Issa GC,
Garcia-Manero G
, Kc D, Dellasala S, Pierce S,
Konopleva M
,
Wierda WG
,
Verstovsek S
,
Daver NG
,
Kadia TM
,
Borthakur G
, O'Brien S,
Estrov Z
, Ravandi F,
Cortes JE
. Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients. Cancer. 2017 Nov 15; 123(22):4391-4402.
PMID:
28743165
; PMCID:
PMC5673547
.
Citations:
47
Fields:
Neo
Neoplasms
Translation:
Humans
Boddu P,
Kantarjian HM
,
Garcia-Manero G
, Ravandi F,
Verstovsek S
,
Jabbour E
,
Borthakur G
,
Konopleva M
,
Bhalla KN
,
Daver N
,
DiNardo CD
,
Benton CB
,
Takahashi K
,
Estrov Z
, Pierce SR,
Andreeff M
,
Cortes JE
,
Kadia TM
. Treated secondary acute myeloid leukemia: a distinct high-risk subset of AML with adverse prognosis. Blood Adv. 2017 Jul 25; 1(17):1312-1323.
PMID:
29296774
; PMCID:
PMC5727976
.
Citations:
26
Fields:
Hem
Hematology
Newberry KJ, Patel K, Masarova L,
Luthra R
, Manshouri T,
Jabbour E
,
Bose P
,
Daver N
, Cortes J,
Kantarjian H
,
Verstovsek S
. Clonal evolution and outcomes in myelofibrosis after ruxolitinib discontinuation. Blood. 2017 08 31; 130(9):1125-1131.
PMID:
28674026
; PMCID:
PMC5580275
.
Citations:
75
Fields:
Hem
Hematology
Translation:
Humans
Bose P
,
Verstovsek S
. Developmental Therapeutics in Myeloproliferative Neoplasms. Clin Lymphoma Myeloma Leuk. 2017 07; 17S:S43-S52.
PMID:
28760302
; PMCID:
PMC5540010
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Masarova L,
Bose P
,
Daver N
,
Pemmaraju N
, Newberry KJ, Manshouri T, Cortes J,
Kantarjian HM
,
Verstovsek S
. Patients with post-essential thrombocythemia and post-polycythemia vera differ from patients with primary myelofibrosis. Leuk Res. 2017 08; 59:110-116.
PMID:
28601551
; PMCID:
PMC5573611
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Kanagal-Shamanna R, Medeiros LJ,
Estrov Z
, Yin CC,
Verstovsek S
,
Konoplev S
,
Jorgensen JL
, Mohammad MM,
Miranda RN
, Zhao C, Lee J,
Zuo Z
,
Bueso-Ramos CE
, Hidalgo-L?pez JE. Morphologic and Molecular Characteristics of De Novo AML With JAK2 V617F Mutation. J Natl Compr Canc Netw. 2017 06; 15(6):790-796.
PMID:
28596259
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P, Wang S,
Patel KP
, Sarwari N, Cortes J,
Kantarjian H
,
Verstovsek S
. Mast cell leukemia (MCL): Clinico-pathologic and molecular features and survival outcome. Leuk Res. 2017 08; 59:105-109.
PMID:
28599188
; PMCID:
PMC5573652
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Courby S, Griesshammer M, Mesa RA, Brachmann CB, Kawashima J, Maltzman JD, Shao L, Xin Y, Huang D, Bajel A. A phase 2 study of momelotinib, a potent JAK1 and JAK2 inhibitor, in patients with polycythemia vera or essential thrombocythemia. Leuk Res. 2017 09; 60:11-17.
PMID:
28622623
; PMCID:
PMC8170698
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L, Todisco G, Manshouri T, Newberry KJ,
Cortes JE
,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Therapy-related myelofibrosis does not appear to exist. Blood Adv. 2017 Jun 13; 1(14):863-866.
PMID:
29296729
; PMCID:
PMC5737601
.
Citations:
1
Fields:
Hem
Hematology
Falchi L,
Kantarjian HM
,
Verstovsek S
. Assessing the thrombotic risk of patients with essential thrombocythemia in the genomic era. Leukemia. 2017 09; 31(9):1845-1854.
PMID:
28529308
; PMCID:
PMC5989314
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Harrison CN, Griesshammer M, Miller C, Passamonti F, Zachee P, Durrant S, Pane F, Guglielmelli P,
Verstovsek S
, Jones MM, Hunter DS, Sun W, Li J, Khan M, Habr D, Masszi T, Kiladjian JJ. Comprehensive haematological control with ruxolitinib in patients with polycythaemia vera resistant to or intolerant of hydroxycarbamide. Br J Haematol. 2018 07; 182(2):279-284.
PMID:
29984424
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Bose P
,
Verstovsek S
. JAK2 inhibitors for myeloproliferative neoplasms: what is next? Blood. 2017 07 13; 130(2):115-125.
PMID:
28500170
; PMCID:
PMC5510786
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
Miller CB, Komrokji RS, Mesa RA, Sun W, Montgomery M,
Verstovsek S
. Practical Measures of Clinical Benefit With Ruxolitinib Therapy: An Exploratory Analysis of COMFORT-I. Clin Lymphoma Myeloma Leuk. 2017 08; 17(8):479-487.
PMID:
28606598
; PMCID:
PMC8148882
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Wang SA
, Hasserjian RP, Tam W, Tsai AG, Geyer JT, George TI, Foucar K, Rogers HJ, Hsi ED, Rea BA, Bagg A,
Bueso-Ramos CE
, Arber DA,
Verstovsek S
, Orazi A. Bone marrow morphology is a strong discriminator between chronic eosinophilic leukemia, not otherwise specified and reactive idiopathic hypereosinophilic syndrome. Haematologica. 2017 08; 102(8):1352-1360.
PMID:
28495918
; PMCID:
PMC5541870
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Bose P
, Abou Zahr A,
Verstovsek S
. Investigational Janus kinase inhibitors in development for myelofibrosis. Expert Opin Investig Drugs. 2017 Jun; 26(6):723-734.
PMID:
28441920
.
Citations:
8
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Tang G
, Hidalgo Lopez JE, Wang SA, Hu S, Ma J, Pierce S, Zuo W, Carballo-Zarate AA, Yin CC,
Tang Z
, Li S,
Medeiros LJ
,
Verstovsek S
,
Bueso-Ramos CE
. Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera. Haematologica. 2017 09; 102(9):1511-1518.
PMID:
28473622
; PMCID:
PMC5685217
.
Citations:
14
Fields:
Hem
Hematology
Translation:
Humans
Cells
Yin CC
, Yates A, Newberry KJ,
Verstovsek S
, Khan M. A Rare Case of Primary Myelofibrosis in a 14-Year-Old Patient With Congenital Asplenia. J Pediatr Hematol Oncol. 2017 05; 39(4):e196-e198.
PMID:
27403772
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Ped
Pediatrics
Translation:
Humans
Vannucchi AM,
Verstovsek S
, Guglielmelli P, Burn TC, Naim A, Paranagama D, Marker M, Gadbaw B, Griesshammer M, Kiladjian JJ. Ruxolitinib reduces JAK2 p.V617F allele burden in patients with polycythemia vera enrolled in the RESPONSE study. Ann Hematol. 2017 Jul; 96(7):1113-1120.
PMID:
28456851
; PMCID:
PMC5486779
.
Citations:
36
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Short NJ,
Kantarjian HM
, Ko H,
Khoury JD
, Ravandi F, Thomas DA,
Garcia-Manero G
, Khouri M,
Cortes JE
,
Wierda WG
,
Verstovsek S
,
Estrov Z
,
Ferrajoli A
, Thompson PA, Pierce S, O'Brien SM,
Jabbour E
. Outcomes of adults with relapsed or refractory Burkitt and high-grade B-cell leukemia/lymphoma. Am J Hematol. 2017 06; 92(6):E114-E117.
PMID:
28295472
; PMCID:
PMC5828013
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Boddu PC,
Kantarjian HM
, Ravandi F,
Garcia-Manero G
,
Verstovsek S
,
Jabbour EJ
,
Takahashi K
,
Bhalla K
,
Konopleva M
,
DiNardo CD
,
Ohanian M
,
Pemmaraju N
,
Jain N
, Pierce S,
Wierda WG
,
Cortes JE
,
Kadia TM
. Characteristics and outcomes of older patients with secondary acute myeloid leukemia according to treatment approach. Cancer. 2017 Aug 15; 123(16):3050-3060.
PMID:
28387922
; PMCID:
PMC5544569
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P, Wang SA, Yin CC, Abaza Y,
Verstovsek S
,
Estrov Z
. A case of lymphocytic variant hypereosinophilic syndrome with sub-diagnostic systemic mastocytosis. Blood Res. 2017 Mar; 52(1):71-73.
PMID:
28401108
; PMCID:
PMC5383595
.
Citations:
Hu Z,
Medeiros LJ
, Wang W, Chen Z, Tang G, Hodjat P, Yang S, Fang L, Li Y,
Verstovsek S
, Hu S. 3q26.2/EVI1 rearrangement is associated with poor prognosis in classical Philadelphia chromosome-negative myeloproliferative neoplasms. Mod Pathol. 2017 07; 30(7):940-951.
PMID:
28338652
.
Citations:
1
Fields:
Pat
Pathology
Translation:
Humans
Cells
Montalban-Bravo G, Huang X, Naqvi K, Jabbour E, Borthakur G, DiNardo CD, Pemmaraju N, Cortes J,
Verstovsek S
, Kadia T, Daver N,
Wierda W
, Alvarado Y,
Konopleva M
, Ravandi F,
Estrov Z
, Jain N, Alfonso A, Brandt M, Sneed T, Chen HC, Yang H,
Bueso-Ramos C
, Pierce S, Estey E, Bohannan Z,
Kantarjian HM
,
Garcia-Manero G
. A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials. Leukemia. 2017 07; 31(7):1659.
PMID:
28338082
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Boddu P, Falchi L,
Hosing C
, Newberry K,
Bose P
,
Verstovsek S
. The role of thrombocytapheresis in the contemporary management of hyperthrombocytosis in myeloproliferative neoplasms: A case-based review. Leuk Res. 2017 07; 58:14-22.
PMID:
28380402
; PMCID:
PMC5466892
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Masarova L,
Patel KP
, Newberry KJ, Cortes J,
Borthakur G
,
Konopleva M
,
Estrov Z
,
Kantarjian H
,
Verstovsek S
. Pegylated interferon alfa-2a in patients with essential thrombocythaemia or polycythaemia vera: a post-hoc, median 83 month follow-up of an open-label, phase 2 trial. Lancet Haematol. 2017 Apr; 4(4):e165-e175.
PMID:
28291640
; PMCID:
PMC5421384
.
Citations:
42
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Strati P, Masarova L,
Bose P
,
Daver N
,
Pemmaraju N
,
Verstovsek S
. Haptoglobin is frequently low in patients with myelofibrosis: Clinical relevance. Leuk Res. 2017 06; 57:85-88.
PMID:
28324773
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Assi R,
Verstovsek S
,
Daver N
. 'JAK-ing' up the treatment of primary myelofibrosis: building better combination strategies. Curr Opin Hematol. 2017 03; 24(2):115-124.
PMID:
28072602
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
Maiti A, Short NJ,
Verstovsek S
, Powers CA, Fullmer CA, Reyes SR,
Bueso-Ramos CE
. Quality and cost comparison of powered versus manual bone marrow biopsy devices in patients with myelofibrosis. Leuk Lymphoma. 2017 10; 58(10):2508-2510.
PMID:
28264600
; PMCID:
PMC5489356
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Strati P,
Bose P
, Lyle L, Gaw K, Zhou L, Pierce SA, Huynh-Lu J,
Hirsch-Ginsberg CF
, Bueso-Mendoza DE,
Bueso-Ramos CE
,
Verstovsek S
. Novel hematological parameters for the evaluation of patients with myeloproliferative neoplasms: the immature platelet and reticulocyte fractions. Ann Hematol. 2017 May; 96(5):733-738.
PMID:
28247057
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Verstovsek S
, Mesa RA, Gotlib J, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Jones M, Kornacki D, Sun K,
Kantarjian H
, COMFORT-I investigators. Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial. J Hematol Oncol. 2017 02 22; 10(1):55.
PMID:
28228106
; PMCID:
PMC5322633
.
Citations:
124
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Savona MR, Mesa RA, Dong H, Maltzman JD, Sharma S, Silverman J, Oh ST, Gotlib J. A phase 2 study of simtuzumab in patients with primary, post-polycythaemia vera or post-essential thrombocythaemia myelofibrosis. Br J Haematol. 2017 Mar; 176(6):939-949.
PMID:
28220932
.
Citations:
19
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Saenz DT, Fiskus W, Qian Y, Manshouri T, Rajapakshe K, Raina K, Coleman KG, Crew AP, Shen A, Mill CP, Sun B, Qiu P, Kadia TM, Pemmaraju N, DiNardo C, Kim MS, Nowak AJ, Coarfa C, Crews CM,
Verstovsek S
,
Bhalla KN
. Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells. Leukemia. 2017 09; 31(9):1951-1961.
PMID:
28042144
; PMCID:
PMC5537055
.
Citations:
72
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Verstovsek S
, Harrison CN, Miller C, Naim AB, Paranagama DC, Habr D, Vannucchi AM, Kiladjian JJ. Markers of iron deficiency in patients with polycythemia vera receiving ruxolitinib or best available therapy. Leuk Res. 2017 05; 56:52-59.
PMID:
28193568
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jain P, Keating M, Renner S,
Cleeland C
, Xuelin H, Gonzalez GN, Harris D, Li P, Liu Z, Veletic I, Rozovski U,
Jain N
, Thompson P,
Bose P
,
DiNardo C
,
Ferrajoli A
, O'Brien S,
Burger J
,
Wierda W
,
Verstovsek S
,
Kantarjian H
,
Estrov Z
. Ruxolitinib for symptom control in patients with chronic lymphocytic leukaemia: a single-group, phase 2 trial. Lancet Haematol. 2017 Feb; 4(2):e67-e74.
PMID:
28089238
; PMCID:
PMC5356368
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jassem E, Niedoszytko M,
Verstovsek S
, Grattan C, Afrin LB, Kinet JP, Mansfield C, Moussy A, Lortholary O, Chandesris MO, Bulai Livideanu C, Paul C, Guillet G, Barete S, Damaj G, Canioni D, Fraitag S, Lhermitte L, Georgin Lavialle S, Frenzel L, Hanssens K, Agopian J, Gaillard R, Auclair C, Dubreuil P, Hermine O. Masitinib for treatment of severely symptomatic indolent systemic mastocytosis: a randomised, placebo-controlled, phase 3 study. Lancet. 2017 02 11; 389(10069):612-620.
PMID:
28069279
; PMCID:
PMC5985971
.
Citations:
35
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Abaza Y,
Kantarjian H
,
Garcia-Manero G
, Estey E,
Borthakur G
,
Jabbour E
, Faderl S, O'Brien S,
Wierda W
, Pierce S, Brandt M, McCue D,
Luthra R
, Patel K,
Kornblau S
,
Kadia T
,
Daver N
,
DiNardo C
,
Jain N
,
Verstovsek S
,
Ferrajoli A
,
Andreeff M
,
Konopleva M
,
Estrov Z
, Foudray M, McCue D, Cortes J, Ravandi F. Long-term outcome of acute promyelocytic leukemia treated with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab. Blood. 2017 03 09; 129(10):1275-1283.
PMID:
28003274
; PMCID:
PMC5413297
.
Citations:
73
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Falchi L,
Bose P
, Newberry KJ,
Verstovsek S
. Approach to patients with essential thrombocythaemia and very high platelet counts: what is the evidence for treatment? Br J Haematol. 2017 Feb; 176(3):352-364.
PMID:
27984634
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Verstovsek S
, Odenike O, Singer JW, Granston T, Al-Fayoumi S, Deeg HJ. Phase 1/2 study of pacritinib, a next generation JAK2/FLT3 inhibitor, in myelofibrosis or other myeloid malignancies. J Hematol Oncol. 2016 12 08; 9(1):137.
PMID:
27931243
; PMCID:
PMC5146859
.
Citations:
29
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Mesa R, Jamieson C, Bhatia R, Deininger MW, Gerds AT, Gojo I, Gotlib J, Gundabolu K, Hobbs G, Klisovic RB, Kropf P, Mohan SR, Oh S, Padron E, Podoltsev N, Pollyea DA, Rampal R, Rein LA, Scott B, Snyder DS, Stein BL,
Verstovsek S
, Wadleigh M, Wang ES, Bergman MA, Gregory KM, Sundar H. Myeloproliferative Neoplasms, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 12; 14(12):1572-1611.
PMID:
27956542
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Bose P
,
Verstovsek S
. Drug Development Pipeline for Myeloproliferative Neoplasms: Potential Future Impact on Guidelines and Management. J Natl Compr Canc Netw. 2016 12; 14(12):1613-1624.
PMID:
27956543
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Abaza Y, Yin CC,
Bueso-Ramos CE
, Wang SA,
Verstovsek S
. Primary autoimmune myelofibrosis: a case report and review of the literature. Int J Hematol. 2017 Apr; 105(4):536-539.
PMID:
27830539
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Mesa R, Vannucchi AM, Yacoub A, Zachee P, Garg M, Lyons R, Koschmieder S, Rinaldi C, Byrne J, Hasan Y, Passamonti F,
Verstovsek S
, Hunter D, Jones MM, Zhen H, Habr D, Martino B. The efficacy and safety of continued hydroxycarbamide therapy versus switching to ruxolitinib in patients with polycythaemia vera: a randomized, double-blind, double-dummy, symptom study (RELIEF). Br J Haematol. 2017 Jan; 176(1):76-85.
PMID:
27858987
; PMCID:
PMC5215488
.
Citations:
31
Fields:
Hem
Hematology
Translation:
Humans
Bose P
,
Verstovsek S
. Myelofibrosis: an update on drug therapy in 2016. Expert Opin Pharmacother. 2016 Dec; 17(18):2375-2389.
PMID:
27774820
; PMCID:
PMC5669058
.
Citations:
5
Fields:
Pha
Pharmacology
Translation:
Humans
Animals
Bose P
,
Verstovsek S
. Investigational histone deacetylase inhibitors (HDACi) in myeloproliferative neoplasms. Expert Opin Investig Drugs. 2016 Dec; 25(12):1393-1403.
PMID:
27756180
; PMCID:
PMC5384641
.
Citations:
14
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Montalban-Bravo G, Huang X, Naqvi K, Jabbour E, Borthakur G, DiNardo CD, Pemmaraju N, Cortes J,
Verstovsek S
, Kadia T, Daver N,
Wierda W
, Alvarado Y,
Konopleva M
, Ravandi F,
Estrov Z
, Jain N, Alfonso A,
Brandt M
, Sneed T, Chen HC, Yang H,
Bueso-Ramos C
, Pierce S, Estey E, Bohannan Z,
Kantarjian HM
,
Garcia-Manero G
. A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials. Leukemia. 2017 02; 31(2):318-324.
PMID:
27795561
.
Citations:
8
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Mascarenhas JO, Talpaz M, Gupta V, Foltz LM, Savona MR, Paquette R, Turner AR, Coughlin P, Winton E, Burn TC, O'Neill P, Clark J, Hunter D, Assad A, Hoffman R,
Verstovsek S
. Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis. Haematologica. 2017 02; 102(2):327-335.
PMID:
27789678
; PMCID:
PMC5286940
.
Citations:
43
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Koller PB,
Kantarjian HM
, Nogueras-Gonzalez GM,
Jabbour E
,
Verstovsek S
,
Borthakur G
,
Estrov Z
,
Wierda WG
,
Garcia-Manero G
,
Ferrajoli A
, Ravandi F, O'Brien SM,
Cortes JE
. Chronic myeloid leukemia among patients with a history of prior malignancies: A tale of dual survivorship. Cancer. 2017 02 15; 123(4):609-616.
PMID:
27763690
; PMCID:
PMC5293656
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Jabbour E
, Faderl S, Sasaki K,
Kadia T
,
Daver N
,
Pemmaraju N
, Patel K,
Khoury JD
,
Bueso-Ramos C
, Bohannan Z, Ravandi F,
Borthakur G
,
Verstovsek S
, Miller D, Maduike R,
Hosing C
,
Kantarjian HM
,
Garcia-Manero G
. Phase 2 study of low-dose clofarabine plus cytarabine for patients with higher-risk myelodysplastic syndrome who have relapsed or are refractory to hypomethylating agents. Cancer. 2017 Feb 15; 123(4):629-637.
PMID:
27741352
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Verstovsek S
. Highlights in polycythemia vera from the 2016 EHA congress. Clin Adv Hematol Oncol. 2016 Oct; 14(10):810-813.
PMID:
27930632
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ustun C, Kluin-Nelemans HC, Reiter A, Sperr WR, George T, Horny HP, Hartmann K, Sotlar K, Damaj G, Hermine O,
Verstovsek S
, Metcalfe DD, Gotlib J, Akin C, Valent P, Arock M. Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice. Haematologica. 2016 10; 101(10):1133-1143.
PMID:
27694501
.
Citations:
21
Fields:
Hem
Hematology
Translation:
Humans
Cells
Rozovski U,
Verstovsek S
, Manshouri T, Dembitz V, Bozinovic K, Newberry K, Zhang Y, Bove JE, Pierce S,
Kantarjian H
,
Estrov Z
. An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis. Haematologica. 2017 01; 102(1):79-84.
PMID:
27686378
; PMCID:
PMC5210235
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Saenz DT,
Fiskus W
, Manshouri T, Rajapakshe K, Krieger S, Sun B, Mill CP,
DiNardo C
,
Pemmaraju N
,
Kadia T
,
Parmar S
, Sharma S,
Coarfa C
, Qiu P,
Verstovsek S
,
Bhalla KN
. BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells. Leukemia. 2017 03; 31(3):678-687.
PMID:
27677740
; PMCID:
PMC5345582
.
Citations:
40
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Gupta V, Mesa RA, Deininger MW, Rivera CE, Sirhan S, Brachmann CB, Collins H, Kawashima J, Xin Y,
Verstovsek S
. A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis. Haematologica. 2017 01; 102(1):94-102.
PMID:
27634203
; PMCID:
PMC5210237
.
Citations:
38
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Gupta V, Harrison C, Hexner EO, Al-Ali HK, Foltz L, Montgomery M, Sun W, Gopalakrishna P,
Kantarjian H
,
Verstovsek S
. The impact of anemia on overall survival in patients with myelofibrosis treated with ruxolitinib in the COMFORT studies. Haematologica. 2016 12; 101(12):e482-e484.
PMID:
27587385
; PMCID:
PMC5479619
.
Citations:
23
Fields:
Hem
Hematology
Translation:
Humans
Mesa RA, Komrokji RS,
Verstovsek S
. Ruxolitinib dose management as a key to long-term treatment success. Int J Hematol. 2016 Oct; 104(4):420-9.
PMID:
27567907
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Singer JW, Al-Fayoumi S, Ma H, Komrokji RS, Mesa R,
Verstovsek S
. Comprehensive kinase profile of pacritinib, a nonmyelosuppressive Janus kinase 2 inhibitor. J Exp Pharmacol. 2016; 8:11-9.
PMID:
27574472
; PMCID:
PMC4993559
.
Citations:
32
Naqvi K
,
Daver N
,
Pemmaraju N
,
Bose P
,
Garcia-Manero G
, Cortes J,
Kantarjian HM
,
Verstovsek S
. Clinical use of ruxolitinib in an academic medical center in unselected patients with myeloproliferative neoplasms not on clinical study. Leuk Lymphoma. 2017 04; 58(4):866-871.
PMID:
27494751
; PMCID:
PMC5521009
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Bose P
,
Verstovsek S
. Prognosis of Primary Myelofibrosis in the Genomic Era. Clin Lymphoma Myeloma Leuk. 2016 08; 16 Suppl:S105-13.
PMID:
27521306
; PMCID:
PMC4987499
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Verstovsek S
, Talpaz M, Ritchie E, Wadleigh M, Odenike O, Jamieson C, Stein B, Uno T, Mesa RA. A phase I, open-label, dose-escalation, multicenter study of the JAK2 inhibitor NS-018 in patients with myelofibrosis. Leukemia. 2017 02; 31(2):393-402.
PMID:
27479177
; PMCID:
PMC5292677
.
Citations:
18
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Manshouri T, Pilling D,
Bueso-Ramos CE
, Newberry KJ, Prijic S, Knez L, Bozinovic K, Harris DM, Spaeth EL,
Post SM
,
Multani AS
, Rampal RK, Ahn J, Levine RL,
Creighton CJ
,
Kantarjian HM
,
Estrov Z
. Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis. J Exp Med. 2016 08 22; 213(9):1723-40.
PMID:
27481130
; PMCID:
PMC4995084
.
Citations:
69
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Nazha A,
Khoury JD
,
Verstovsek S
,
Daver N
. Second line therapies in polycythemia vera: What is the optimal strategy after hydroxyurea failure? Crit Rev Oncol Hematol. 2016 Sep; 105:112-7.
PMID:
27401783
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Chihara D, Masarova L, Newberry KJ, Maeng H, Ravandi F,
Garcia-Manero G
,
Ferrajoli A
, Cortes J,
Kantarjian H
,
Verstovsek S
. Long-term results of a phase II trial of lenalidomide plus prednisone therapy for patients with myelofibrosis. Leuk Res. 2016 09; 48:1-5.
PMID:
27416326
; PMCID:
PMC5407688
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L, Wang W, Newberry KJ,
Kantarjian H
,
Verstovsek S
. Complete remission in a patient with JAK2- and IDH2-positive myelofibrosis. Blood. 2016 08 11; 128(6):877-80.
PMID:
27325105
; PMCID:
PMC4982456
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Zahr AA, Salama ME, Carreau N, Tremblay D,
Verstovsek S
, Mesa R, Hoffman R, Mascarenhas J. Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies. Haematologica. 2016 06; 101(6):660-71.
PMID:
27252511
; PMCID:
PMC5013940
.
Citations:
35
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Wang SA, Tam W, Tsai AG, Arber DA, Hasserjian RP, Geyer JT, George TI, Czuchlewski DR, Foucar K, Rogers HJ, Hsi ED, Bryan Rea B, Bagg A, Dal Cin P, Zhao C, Kelley TW,
Verstovsek S
,
Bueso-Ramos C
, Orazi A. Targeted next-generation sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified. Mod Pathol. 2016 08; 29(8):854-64.
PMID:
27174585
.
Citations:
23
Fields:
Pat
Pathology
Translation:
Humans
Vaddi K,
Verstovsek S
, Kiladjian JJ. Ruxolitinib: a targeted treatment option for patients with polycythemia vera. Blood Lymphat Cancer. 2016; 6:7-19.
PMID:
31360077
; PMCID:
PMC6467337
.
Citations:
Ustun C, Gotlib J,
Popat U
, Artz A, Litzow M, Reiter A, Nakamura R, Kluin-Nelemans HC,
Verstovsek S
, Gajewski J, Perales MA, George T, Shore T, Sperr W, Saber W, Kota V, Yavuz AS, Pullarkat V, Rogosheske J, Hogan W, Van Besien K, Hagglund H, Damaj G, Metcalfe DD, Deeg HJ, Devine S, Weisdorf D, Akin C, Valent P, Arock M, Horny HP. Consensus Opinion on Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis. Biol Blood Marrow Transplant. 2016 08; 22(8):1348-1356.
PMID:
27131865
.
Citations:
24
Fields:
Hem
Hematology
Tra
Transplantation
Translation:
Humans
Verstovsek S
, Vannucchi AM, Griesshammer M, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Kirito K, Besses C, Hino M, Moiraghi B, Miller CB, Cazzola M, Rosti V, Mesa R, Jones MM, Zhen H, Li J, Francillard N, Habr D, Masszi T, Blau I, Kiladjian JJ. Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial. Haematologica. 2016 07; 101(7):821-9.
PMID:
27102499
; PMCID:
PMC5004461
.
Citations:
65
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Rozovski U, Harris DM, Li P, Liu Z, Wu JY, Grgurevic S, Faderl S,
Ferrajoli A
,
Wierda WG
, Martinez M,
Verstovsek S
, Keating MJ,
Estrov Z
. At High Levels, Constitutively Activated STAT3 Induces Apoptosis of Chronic Lymphocytic Leukemia Cells. J Immunol. 2016 05 15; 196(10):4400-9.
PMID:
27076684
; PMCID:
PMC4868805
.
Citations:
15
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Bryan JC,
Verstovsek S
. Overcoming treatment challenges in myelofibrosis and polycythemia vera: the role of ruxolitinib. Cancer Chemother Pharmacol. 2016 06; 77(6):1125-42.
PMID:
27017614
; PMCID:
PMC4882345
.
Citations:
16
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Animals
Loghavi S
,
Bueso-Ramos CE
, Kanagal-Shamanna R, Ok CY, Salim AA,
Routbort MJ
, Mehrotra M,
Verstovsek S
, Medeiros LJ,
Luthra R
,
Patel KP
. Myeloproliferative Neoplasms With Calreticulin Mutations Exhibit Distinctive Morphologic Features. Am J Clin Pathol. 2016 03; 145(3):418-27.
PMID:
27124925
.
Citations:
1
Fields:
Pat
Pathology
Translation:
Humans
Cells
Jain P,
Kantarjian H
, Sasaki K,
Jabbour E
, Dasarathula J, Nogueras Gonzalez G,
Verstovsek S
,
Borthakur G
,
Wierda W
,
Kadia T
, Dellasala S, Pierce S, Ravandi F, O'Brien S, Cortes J. Analysis of 2013 European LeukaemiaNet (ELN) responses in chronic phase CML across four frontline TKI modalities and impact on clinical outcomes. Br J Haematol. 2016 Apr; 173(1):114-26.
PMID:
26846160
; PMCID:
PMC4809772
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Pemmaraju N
,
Kantarjian H
, Ravandi F, Nogueras-Gonzalez GM, Huang X, O'Brien S,
Wierda W
,
Garcia-Manero G
, Thomas D, Pierce S,
Verstovsek S
,
Borthakur G
, Cortes J. Patient Characteristics and Outcomes in Adolescents and Young Adults (AYA) With Acute Myeloid Leukemia (AML). Clin Lymphoma Myeloma Leuk. 2016 Apr; 16(4):213-222.e2.
PMID:
26838606
; PMCID:
PMC4811701
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Mesa R,
Verstovsek S
, Griesshammer M, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Zhen H, Jones MM, Parasuraman S, Li J, Habr D, Vannucchi AM, Kiladjian JJ, Masszi T, C?t? I. Changes in quality of life and disease-related symptoms in patients with polycythemia vera receiving ruxolitinib or standard therapy. Eur J Haematol. 2016 Aug; 97(2):192-200.
PMID:
26608702
.
Citations:
21
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Falchi L,
Verstovsek S
,
Ravandi-Kashani F
,
Kantarjian HM
. The evolution of arsenic in the treatment of acute promyelocytic leukemia and other myeloid neoplasms: Moving toward an effective oral, outpatient therapy. Cancer. 2016 Apr 15; 122(8):1160-8.
PMID:
26716387
; PMCID:
PMC5042140
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Bose P
,
Verstovsek S
. The evolution and clinical relevance of prognostic classification systems in myelofibrosis. Cancer. 2016 Mar 01; 122(5):681-92.
PMID:
26717494
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P,
Verstovsek S
, Wang W,
Loghavi S
,
Torres HA
,
Estrov Z
,
Patel KP
,
Pemmaraju N
. DNMT3A, TET2, and JAK2 mutations in polycythemia vera following long-term remission of secondary acute myeloid leukemia. Leuk Lymphoma. 2016 08; 57(8):1969-73.
PMID:
26700872
; PMCID:
PMC4919228
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Atallah E, Mascarenhas J, Sun H,
Montgomery M
, Gupta V, Mesa R, Gotlib J. Efficacy of ruxolitinib on hepatomegaly in patients with myelofibrosis. Leukemia. 2016 06; 30(6):1413-5.
PMID:
26526986
; PMCID:
PMC4895165
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Mehrotra M,
Luthra R
,
Singh RR
, Barkoh BA, Galbincea J, Mehta P, Goswami RS, Jabbar KJ,
Loghavi S
,
Medeiros LJ
,
Verstovsek S
,
Patel KP
. Clinical validation of a multipurpose assay for detection and genotyping of CALR mutations in myeloproliferative neoplasms. Am J Clin Pathol. 2015 Nov; 144(5):746-55.
PMID:
26486739
.
Citations:
3
Fields:
Pat
Pathology
Translation:
Humans
Cells
Todisco G, Manshouri T,
Verstovsek S
, Masarova L, Pierce SA, Keating MJ,
Estrov Z
. Chronic lymphocytic leukemia and myeloproliferative neoplasms concurrently diagnosed: clinical and biological characteristics. Leuk Lymphoma. 2016 May; 57(5):1054-9.
PMID:
26402369
; PMCID:
PMC4837105
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Shanavas M,
Popat U
, Michaelis LC, Fauble V, McLornan D, Klisovic R, Mascarenhas J, Tamari R, Arcasoy MO, Davies J, Gergis U, Ukaegbu OC,
Kamble RT
, Storring JM, Majhail NS, Romee R,
Verstovsek S
, Pagliuca A, Vasu S, Ernst B, Atenafu EG, Hanif A,
Champlin R
, Hari P, Gupta V. Outcomes of Allogeneic Hematopoietic Cell Transplantation in?Patients with Myelofibrosis with Prior Exposure to Janus Kinase 1/2 Inhibitors. Biol Blood Marrow Transplant. 2016 Mar; 22(3):432-40.
PMID:
26493563
; PMCID:
PMC5030817
.
Citations:
41
Fields:
Hem
Hematology
Tra
Transplantation
Translation:
Humans
CT
Clinical Trials
Livun A, Newberry KJ, Manshouri T, Kusec R,
Verstovsek S
. Genes Involved in Maintaining the Bone Marrow Stroma Are Dysregulated in Patients with Myelofibrosis: Lenalidomide Treatment Up-regulates SOCS3. Anticancer Res. 2015 Oct; 35(10):5219-23.
PMID:
26408680
; PMCID:
PMC4913273
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Masarova L, Cherry M, Newberry KJ,
Estrov Z
,
Cortes JE
,
Kantarjian HM
,
Verstovsek S
. Secondary solid tumors and lymphoma in patients with essential thrombocythemia and polycythemia vera - single center experience. Leuk Lymphoma. 2016; 57(1):237-9.
PMID:
25904378
; PMCID:
PMC4712116
.
Citations:
14
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Komrokji RS. A comprehensive review of pacritinib in myelofibrosis. Future Oncol. 2015; 11(20):2819-30.
PMID:
26367195
; PMCID:
PMC4918816
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Daver N,
Kantarjian H
, Ravandi F, Estey E, Wang X,
Garcia-Manero G
, Jabbour E,
Konopleva M
, O'Brien S,
Verstovsek S
, Kadia T, Dinardo C, Pierce S, Huang X, Pemmaraju N, Diaz-Pines-Mateo M, Cortes J, Borthakur G. A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome. Leukemia. 2016 Feb; 30(2):268-73.
PMID:
26365212
; PMCID:
PMC4790089
.
Citations:
37
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ravandi F, O'Brien SM,
Cortes JE
, Thomas DM, Garris R, Faderl S,
Burger JA
,
Rytting ME
,
Ferrajoli A
,
Wierda WG
,
Verstovsek S
,
Champlin R
,
Kebriaei P
, McCue DA, Huang X,
Jabbour E
,
Garcia-Manero G
,
Estrov Z
,
Kantarjian HM
. Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Cancer. 2015 Dec 01; 121(23):4158-64.
PMID:
26308885
; PMCID:
PMC4666803
.
Citations:
61
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Rajasekaran A, Ngo TT, Abdelrahim M, Glass W, Podoll A,
Verstovsek S
,
Abudayyeh A
. Primary myelofibrosis associated glomerulopathy: significant improvement after therapy with ruxolitinib. BMC Nephrol. 2015 Aug 01; 16:121.
PMID:
26232031
; PMCID:
PMC4521341
.
Citations:
4
Fields:
Nep
Nephrology
Translation:
Humans
Falchi L,
Verstovsek S
. Eosinophilia in Hematologic Disorders. Immunol Allergy Clin North Am. 2015 Aug; 35(3):439-52.
PMID:
26209894
; PMCID:
PMC4515577
.
Citations:
7
Fields:
All
Allergy and Immunology
Translation:
Humans
Deininger M, Radich J, Burn TC, Huber R, Paranagama D,
Verstovsek S
. The effect of long-term ruxolitinib treatment on JAK2p.V617F allele burden in patients with myelofibrosis. Blood. 2015 Sep 24; 126(13):1551-4.
PMID:
26228487
; PMCID:
PMC4582331
.
Citations:
82
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Patel KP
, Newberry KJ,
Luthra R
,
Jabbour E
, Pierce S,
Cortes J
,
Singh R
, Mehrotra M,
Routbort MJ
, Luthra M, Manshouri T, Santos FP,
Kantarjian H
,
Verstovsek S
. Correlation of mutation profile and response in patients with myelofibrosis treated with ruxolitinib. Blood. 2015 Aug 06; 126(6):790-7.
PMID:
26124496
; PMCID:
PMC4528066
.
Citations:
74
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Chen Z, Wang W,
Verstovsek S
, Cortes JE,
Medeiros LJ
,
Hu S
. Chronic myelogenous leukemia in patients with MPL or JAK2 mutation-positive myeloproliferative neoplasm. Int J Lab Hematol. 2015 Dec; 37(6):e150-2.
PMID:
26086872
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Daver N
, Cortes J, Newberry K,
Jabbour E
, Zhou L, Wang X, Pierce S,
Kadia T
, Sasaki K,
Borthakur G
, Ravandi F,
Pemmaraju N
,
Kantarjian H
,
Verstovsek S
. Ruxolitinib in combination with lenalidomide as therapy for patients with myelofibrosis. Haematologica. 2015 Aug; 100(8):1058-63.
PMID:
26088933
; PMCID:
PMC5004422
.
Citations:
29
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Vannucchi AM,
Kantarjian HM
, Gotlib J, Mesa RA, Sarlis NJ, Peng W, Sandor V, Gopalakrishna P, Hmissi A, Stalbovskaya V, Gupta V, Harrison C,
Verstovsek S
, COMFORT Investigators, Kiladjian JJ, Cervantes F. A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosis. Haematologica. 2015 Sep; 100(9):1139-45.
PMID:
26069290
; PMCID:
PMC4800694
.
Citations:
83
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Badar T,
Kantarjian HM
, Ravandi F,
Jabbour E
,
Borthakur G
,
Cortes JE
,
Pemmaraju N
, Pierce SR, Newberry KJ,
Daver N
,
Verstovsek S
. Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic/acute myeloid leukemia phase. Leuk Res. 2015 Sep; 39(9):950-6.
PMID:
26183878
; PMCID:
PMC4546869
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Sanford D,
DiNardo CD
, Tang G,
Cortes JE
,
Verstovsek S
,
Jabbour E
, Ravandi F,
Kantarjian H
,
Garcia-Manero G
. Jumping Translocations in Myeloid Malignancies Associated With Treatment Resistance and Poor Survival. Clin Lymphoma Myeloma Leuk. 2015 Sep; 15(9):556-62.
PMID:
26141213
; PMCID:
PMC4837956
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Falchi L, Newberry KJ,
Verstovsek S
. New Therapeutic Approaches in Polycythemia Vera. Clin Lymphoma Myeloma Leuk. 2015 Jun; 15 Suppl:S27-33.
PMID:
26297275
; PMCID:
PMC4548804
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
. New therapies for polycythemia vera. Clin Adv Hematol Oncol. 2015 Jun; 13(6):356-8.
PMID:
26352890
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Pieri L, Pancrazzi A, Pacilli A, Rabuzzi C, Rotunno G, Fanelli T, Guglielmelli P, Fjerza R, Paoli C,
Verstovsek S
, Vannucchi AM. JAK2V617F complete molecular remission in polycythemia vera/essential thrombocythemia patients treated with ruxolitinib. Blood. 2015 May 21; 125(21):3352-3.
PMID:
25999444
.
Citations:
15
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Loghavi S
,
Pemmaraju N
, Kanagal-Shamanna R, Mehrotra M,
Medeiros LJ
,
Luthra R
,
Lin P
,
Huh Y
,
Kantarjian HM
,
Cortes JE
,
Verstovsek S
,
Patel KP
. Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with CALR mutation and BCR-ABL1. Blood. 2015 May 21; 125(21):3360-3.
PMID:
25999449
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Stein BL, Giles F, Harrison CN,
Verstovsek S
, Cervantes F. Novel therapies for myelofibrosis. Leuk Lymphoma. 2015; 56(10):2768-78.
PMID:
25860240
; PMCID:
PMC5008691
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Winton EF, Talpaz M,
Verstovsek S
, Kiladjian JJ. Ruxolitinib for the treatment of patients with polycythemia vera. Expert Rev Hematol. 2015 Aug; 8(4):391-401.
PMID:
25980454
; PMCID:
PMC4627585
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Masarova L, Newberry KJ, Pierce SA,
Estrov Z
,
Cortes JE
,
Kantarjian HM
,
Verstovsek S
. Association of lymphoid malignancies and Philadelphia-chromosome negative myeloproliferative neoplasms: Clinical characteristics, therapy and outcome. Leuk Res. 2015 Aug; 39(8):822-7.
PMID:
26012362
; PMCID:
PMC4547830
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jain P,
Verstovsek S
,
Loghavi S
,
Jorgensen JL
,
Patel KP
,
Estrov Z
,
Fayad L
,
Pemmaraju N
. Durable remission with rituximab in a patient with an unusual variant of Castleman's disease with myelofibrosis-TAFRO syndrome. Am J Hematol. 2015 Nov; 90(11):1091-2.
PMID:
25808231
; PMCID:
PMC4580493
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Cells
Gowin K,
Verstovsek S
, Daver N, Pemmaraju N, Valdez R, Kosiorek H, Dueck A, Mesa R. Limitations of fibrosis grade as diagnostic criteria for post polycythemia vera and essential thrombocytosis myelofibrosis. Leuk Res. 2015 Jul; 39(7):684-8.
PMID:
25922307
; PMCID:
PMC8157912
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Stein BL, Gotlib J, Arcasoy M, Nguyen MH, Shah N, Moliterno A, Jamieson C, Pollyea DA, Scott B, Wadleigh M, Levine R, Komrokji R, Klisovic R, Gundabolu K, Kropf P, Wetzler M, Oh ST, Ribeiro R, Paschal R, Mohan S, Podoltsev N, Prchal J, Talpaz M, Snyder D,
Verstovsek S
, Mesa RA. Historical views, conventional approaches, and evolving management strategies for myeloproliferative neoplasms. J Natl Compr Canc Netw. 2015 Apr; 13(4):424-34.
PMID:
25870379
; PMCID:
PMC8161684
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P,
Kantarjian H
, Alattar ML,
Jabbour E
, Sasaki K, Nogueras Gonzalez G, Dellasala S, Pierce S,
Verstovsek S
,
Wierda W
,
Borthakur G
, Ravandi F, O'Brien S, Cortes J. Long-term molecular and cytogenetic response and survival outcomes with imatinib 400 mg, imatinib 800 mg, dasatinib, and nilotinib in patients with chronic-phase chronic myeloid leukaemia: retrospective analysis of patient data from five clinical trials. Lancet Haematol. 2015 Mar; 2(3):e118-28.
PMID:
26687797
; PMCID:
PMC4854752
.
Citations:
29
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Badar T,
Cortes JE
, Ravandi F, O'Brien S,
Verstovsek S
,
Garcia-Manero G
,
Kantarjian H
,
Borthakur G
. Phase I study of S-trans, trans-farnesylthiosalicylic acid (salirasib), a novel oral RAS inhibitor in patients with refractory hematologic malignancies. Clin Lymphoma Myeloma Leuk. 2015 Jul; 15(7):433-438.e2.
PMID:
25795639
; PMCID:
PMC4509631
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Sasaki K, Gotlib JR, Mesa RA, Newberry KJ, Ravandi F,
Cortes JE
, Kelly P, Kutok JL,
Kantarjian HM
,
Verstovsek S
. Phase II evaluation of IPI-926, an oral Hedgehog inhibitor, in patients with myelofibrosis. Leuk Lymphoma. 2015 Jul; 56(7):2092-7.
PMID:
25641433
; PMCID:
PMC4919663
.
Citations:
30
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Benton CB
, Tanaka M, Wilson C, Pierce S, Zhou L, Cortes J,
Kantarjian H
,
Verstovsek S
. Increased likelihood of post-polycythemia vera myelofibrosis in Ph-negative MPN patients with chromosome 12 abnormalities. Leuk Res. 2015 Apr; 39(4):419-23.
PMID:
25687833
; PMCID:
PMC4847531
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Van Roosbroeck K
,
Verstovsek S
,
Calin GA
. Long non-coding RNAs in primary myelofibrosis: the dark matter in hematopoietic progenitor cells? Leuk Lymphoma. 2015 Feb; 56(2):281-2.
PMID:
25093380
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Kiladjian JJ, Griesshammer M, Masszi T, Durrant S, Passamonti F, Harrison CN, Pane F, Zachee P, Mesa R, He S, Jones MM, Garrett W, Li J, Pirron U, Habr D,
Verstovsek S
, Vannucchi AM. Ruxolitinib versus standard therapy for the treatment of polycythemia vera. N Engl J Med. 2015 Jan 29; 372(5):426-35.
PMID:
25629741
; PMCID:
PMC4358820
.
Citations:
281
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner EO, Lyons RM, Raza A, Vaddi K, Sun W, Peng W, Sandor V,
Kantarjian H
, COMFORT-I investigators. Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I. Haematologica. 2015 Apr; 100(4):479-88.
PMID:
25616577
; PMCID:
PMC4380721
.
Citations:
88
Fields:
Hem
Hematology
Translation:
Humans
Arana Yi C, Tam CS,
Verstovsek S
. Efficacy and safety of ruxolitinib in the treatment of patients with myelofibrosis. Future Oncol. 2015; 11(5):719-33.
PMID:
25757677
; PMCID:
PMC4920055
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Mesa RA,
Verstovsek S
, Gupta V, Mascarenhas JO, Atallah E, Burn T, Sun W, Sandor V, Gotlib J. Effects of ruxolitinib treatment on metabolic and nutritional parameters in patients with myelofibrosis from COMFORT-I. Clin Lymphoma Myeloma Leuk. 2015 Apr; 15(4):214-221.e1.
PMID:
25682576
; PMCID:
PMC4418454
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Kroll MH
, Michaelis LC,
Verstovsek S
. Mechanisms of thrombogenesis in polycythemia vera. Blood Rev. 2015 Jul; 29(4):215-21.
PMID:
25577686
; PMCID:
PMC4466074
.
Citations:
25
Fields:
Hem
Hematology
Translation:
Humans
Rampal R, Ahn J, Abdel-Wahab O, Nahas M, Wang K, Lipson D, Otto GA, Yelensky R, Hricik T, McKenney AS, Chiosis G, Chung YR, Pandey S, van den Brink MR, Armstrong SA, Dogan A, Intlekofer A, Manshouri T, Park CY,
Verstovsek S
, Rapaport F, Stephens PJ, Miller VA, Levine RL. Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):E5401-10.
PMID:
25516983
; PMCID:
PMC4273376
.
Citations:
105
Fields:
Sci
Science
Translation:
Humans
Animals
Yacoub A, Odenike O,
Verstovsek S
. Ruxolitinib: long-term management of patients with myelofibrosis and future directions in the treatment of myeloproliferative neoplasms. Curr Hematol Malig Rep. 2014 Dec; 9(4):350-9.
PMID:
25145552
; PMCID:
PMC4223534
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Hoffman R, Mascarenhas J, McCoon P, Tang W,
Cortes J
,
Kantarjian H
, Soria JC, Bahleda R, Ribrag V. A phase I, open-label, multi-center study of the JAK2 inhibitor AZD1480 in patients with myelofibrosis. Leuk Res. 2015 Feb; 39(2):157-63.
PMID:
25530567
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Pozdnyakova O, Hasserjian RP,
Verstovsek S
, Orazi A. Impact of bone marrow pathology on the clinical management of Philadelphia chromosome-negative myeloproliferative neoplasms. Clin Lymphoma Myeloma Leuk. 2015 May; 15(5):253-61.
PMID:
25515354
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Verstovsek S
, Komrokji RS. Novel and emerging therapies for the treatment of polycythemia vera. Expert Rev Hematol. 2015 Feb; 8(1):101-13.
PMID:
25353086
; PMCID:
PMC4934659
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Daver N
,
Kantarjian H
, Marcucci G, Pierce S, Brandt M,
Dinardo C
,
Pemmaraju N
,
Garcia-Manero G
, O'Brien S,
Ferrajoli A
,
Verstovsek S
,
Popat U
,
Hosing C
,
Anderlini P
,
Borthakur G
,
Kadia T
,
Cortes J
, Ravandi F. Clinical characteristics and outcomes in patients with acute promyelocytic leukaemia and hyperleucocytosis. Br J Haematol. 2015 Mar; 168(5):646-53.
PMID:
25312977
; PMCID:
PMC4323735
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Passamonti F, Vannucchi AM, Harrison C,
Kantarjian H
,
Verstovsek S
, Cervantes F, Morra E. Ruxolitinib and survival improvement in patients with myelofibrosis. Leukemia. 2015 Mar; 29(3):739-40.
PMID:
25249013
.
Citations:
6
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Pemmaraju N
,
Kantarjian H
,
Kadia T
,
Cortes J
,
Borthakur G
, Newberry K,
Garcia-Manero G
, Ravandi F,
Jabbour E
, Dellasala S, Pierce S,
Verstovsek S
. A phase I/II study of the Janus kinase (JAK)1 and 2 inhibitor ruxolitinib in patients with relapsed or refractory acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015 Mar; 15(3):171-6.
PMID:
25441108
; PMCID:
PMC4344906
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jabbar KJ,
Medeiros LJ
, Wang SA,
Miranda RN
, Johnson MR,
Verstovsek S
,
Jorgensen JL
. Flow cytometric immunophenotypic analysis of systemic mastocytosis involving bone marrow. Arch Pathol Lab Med. 2014 Sep; 138(9):1210-4.
PMID:
25171703
.
Citations:
1
Fields:
Pat
Pathology
Translation:
Humans
Cells
Strati P,
Pemmaraju N
,
Estrov Z
, Cardenas-Turanzas M, Pierce S, Newberry KJ,
Daver N
,
Cortes J
,
Kantarjian H
,
Verstovsek S
. Clinical significance of microcytosis in patients with primary myelofibrosis. Leuk Res. 2014 Oct; 38(10):1212-6.
PMID:
25217891
; PMCID:
PMC4182146
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Barosi G, Tefferi A, Besses C, Birgegard G, Finazzi G, Gisslinger H, Griesshammer M, Harrison C, Mesa R, Mc Mullin MF, Pardanani A, Passamonti F, Samuelsson J, Vannucchi AM, Silver RT,
Verstovsek S
, Tognoni G, Barbui T, Cervantes F, Hehlmann R, Hermouet S, Kiladjian JJ, Kr?ger N, Reiter A. Clinical end points for drug treatment trials in BCR-ABL1-negative classic myeloproliferative neoplasms: consensus statements from European LeukemiaNET (ELN) and Internation Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT). Leukemia. 2015 Jan; 29(1):20-6.
PMID:
25151955
; PMCID:
PMC8764620
.
Citations:
18
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Verstovsek S
. Preface. Best Pract Res Clin Haematol. 2014 Jun; 27(2):81-2.
PMID:
25189719
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Pemmaraju N
, Shah D,
Kantarjian H
,
Orlowski RZ
,
Baladandayuthapani V
,
Jain N
, Wagner V,
Garcia-Manero G
, Shah J, Ravandi F, Pierce S,
Takahashi K
,
Daver N
, Nazha A,
Verstovsek S
,
Jabbour E
, De Lima M,
Champlin R
, Cortes J,
Qazilbash MH
, Nogueras Gonz?lez GM. Characteristics and outcomes of patients with multiple myeloma who develop therapy-related myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015 Feb; 15(2):110-4.
PMID:
25107338
; PMCID:
PMC4294996
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N
,
Verstovsek S
. Ruxolitinib and DNA methyltransferase-inhibitors: a foray into combination regimens in myelofibrosis. Leuk Lymphoma. 2015 Feb; 56(2):279-80.
PMID:
24913500
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Daver N
, Shastri A,
Kadia T
, Newberry K,
Pemmaraju N
,
Jabbour E
, Zhou L, Pierce S,
Cortes J
,
Kantarjian H
,
Verstovsek S
. Phase II study of pomalidomide in combination with prednisone in patients with myelofibrosis and significant anemia. Leuk Res. 2014 Sep; 38(9):1126-9.
PMID:
25047979
; PMCID:
PMC4157096
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka MM, Mu J, Chen DZ, Srour EF, Chitteti BR, HogenEsch H, Tu X, Bellido TM, Boswell HS, Manshouri T,
Verstovsek S
, Yoder MC, Kapur R, Cardoso AA, Carlesso N. Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-?B-dependent manner. Cell Stem Cell. 2014 Jul 03; 15(1):51-65.
PMID:
24996169
; PMCID:
PMC4398997
.
Citations:
92
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Newberry KJ,
Naqvi K
, Nguyen KT, Cardenas-Turanzas M, Florencia Tanaka M, Pierce S,
Verstovsek S
. Comorbidities predict worse prognosis in patients with primary myelofibrosis. Cancer. 2014 Oct 01; 120(19):2996-3002.
PMID:
24917509
; PMCID:
PMC4838182
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Pemmaraju N
, Chang E,
Daver N
, Patel K,
Jorgensen J
,
Sabloff B
,
Verstovsek S
,
Borthakur G
. Extramedullary acute myeloid leukemia: leukemic pleural effusion, case report and review of the literature. Front Oncol. 2014; 4:130.
PMID:
24918086
; PMCID:
PMC4040935
.
Citations:
2
Verstovsek S
, Santos FP. Efficacy of ruxolitinib for myelofibrosis. Expert Opin Pharmacother. 2014 Jul; 15(10):1465-73.
PMID:
24856675
; PMCID:
PMC4824286
.
Citations:
2
Fields:
Pha
Pharmacology
Translation:
Humans
Falchi L, Mehrotra M, Newberry KJ, Lyle LM, Lu G,
Patel KP
, Luthra R,
Popat U
,
Verstovsek S
. ETV6-FLT3 fusion gene-positive, eosinophilia-associated myeloproliferative neoplasm successfully treated with sorafenib and allogeneic stem cell transplant. Leukemia. 2014 Oct; 28(10):2090-2.
PMID:
24854988
; PMCID:
PMC4824944
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Rozovski U,
Wu JY
, Harris DM, Liu Z, Li P, Hazan-Halevy I,
Ferrajoli A
,
Burger JA
, O'Brien S,
Jain N
,
Verstovsek S
,
Wierda WG
, Keating MJ,
Estrov Z
. Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells. Blood. 2014 Jun 12; 123(24):3797-802.
PMID:
24778152
; PMCID:
PMC4055926
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
Cells
Valent P, Sotlar K, Sperr WR, Escribano L, Yavuz S, George TI, Kluin-Nelemans HC, Butterfield JH, Ustun C, Hornick JL, Triggiani M, Radia D, Akin C, Hartmann K, Gotlib J, Schwartz LB,
Verstovsek S
, Orfao A, Metcalfe DD, Horny HP, Reiter A, Hermine O, H?gglund H, Arock M. Refined diagnostic criteria and classification of mast cell leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal. Ann Oncol. 2014 Sep; 25(9):1691-1700.
PMID:
24675021
; PMCID:
PMC4155468
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Gupta V, Gotlib J, Radich JP, Rondelli D,
Verstovsek S
, Deeg HJ, Kr?ger NM. Janus kinase inhibitors and allogeneic stem cell transplantation for myelofibrosis. Biol Blood Marrow Transplant. 2014 Sep; 20(9):1274-81.
PMID:
24680977
; PMCID:
PMC4465357
.
Citations:
10
Fields:
Hem
Hematology
Tra
Transplantation
Translation:
Humans
Verstovsek S
. Changing myelofibrosis's natural course at last. Blood. 2014 Mar 20; 123(12):1776-7.
PMID:
24652960
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Sever M, Newberry KJ,
Verstovsek S
. Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea. Leuk Lymphoma. 2014 Dec; 55(12):2685-90.
PMID:
24524340
; PMCID:
PMC4835800
.
Citations:
9
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Tefferi A, Hudgens S, Mesa R, Gale RP,
Verstovsek S
, Passamonti F, Rivera C, Tencer T, Khan ZM, Cervantes F. Use of the Functional Assessment of Cancer Therapy--anemia in persons with myeloproliferative neoplasm-associated myelofibrosis and anemia. Clin Ther. 2014 Apr 01; 36(4):560-6.
PMID:
24636526
.
Citations:
9
Fields:
Dru
Drug Therapy
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Wang SA
, Hasserjian RP, Fox PS, Rogers HJ, Geyer JT, Chabot-Richards D, Weinzierl E, Hatem J, Jaso J, Kanagal-Shamanna R, Stingo FC,
Patel KP
, Mehrotra M,
Bueso-Ramos C
, Young KH,
Dinardo CD
,
Verstovsek S
, Tiu RV, Bagg A, Hsi ED, Arber DA, Foucar K,
Luthra R
, Orazi A. Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms. Blood. 2014 Apr 24; 123(17):2645-51.
PMID:
24627528
; PMCID:
PMC4067498
.
Citations:
61
Fields:
Hem
Hematology
Translation:
Humans
Cells
Verstovsek S
, Passamonti F, Rambaldi A, Barosi G, Rosen PJ, Rumi E, Gattoni E, Pieri L, Guglielmelli P, Elena C, He S, Contel N, Mookerjee B, Sandor V, Cazzola M,
Kantarjian HM
, Barbui T, Vannucchi AM. A phase 2 study of ruxolitinib, an oral JAK1 and JAK2 Inhibitor, in patients with advanced polycythemia vera who are refractory or intolerant to hydroxyurea. Cancer. 2014 Feb 15; 120(4):513-20.
PMID:
24258498
; PMCID:
PMC4231215
.
Citations:
62
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Mughal TI, Vaddi K, Sarlis NJ,
Verstovsek S
. Myelofibrosis-associated complications: pathogenesis, clinical manifestations, and effects on outcomes. Int J Gen Med. 2014; 7:89-101.
PMID:
24501543
; PMCID:
PMC3912063
.
Citations:
32
Nazha A,
Jorgensen JL
,
Verstovsek S
. Paroxysmal nocturnal hemoglobinuria is not a cause of anemia in patients with myelofibrosis. Leuk Lymphoma. 2014 Sep; 55(9):2215-6.
PMID:
24359246
; PMCID:
PMC4820818
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
DiNardo CD, Daver N,
Jain N
, Pemmaraju N,
Bueso-Ramos C
,
Yin CC
, Pierce S, Jabbour E, Cortes JE,
Kantarjian HM
,
Garcia-Manero G
,
Verstovsek S
. Myelodysplastic/myeloproliferative neoplasms, unclassifiable (MDS/MPN, U): natural history and clinical outcome by treatment strategy. Leukemia. 2014 Apr; 28(4):958-61.
PMID:
24492324
; PMCID:
PMC3981947
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Gotlib J, Gupta V, Atallah E, Mascarenhas J, Quintas-Cardama A, Sun W, Sarlis NJ, Sandor V, Levy RS,
Kantarjian HM
, Mesa RA. Management of cytopenias in patients with myelofibrosis treated with ruxolitinib and effect of dose modifications on efficacy outcomes. Onco Targets Ther. 2013; 7:13-21.
PMID:
24368888
; PMCID:
PMC3869911
.
Citations:
23
Verstovsek S
, Tam CS, Wadleigh M, Sokol L, Smith CC, Bui LA, Song C, Clary DO, Olszynski P,
Cortes J
,
Kantarjian H
, Shah NP. Phase I evaluation of XL019, an oral, potent, and selective JAK2 inhibitor. Leuk Res. 2014 Mar; 38(3):316-22.
PMID:
24374145
; PMCID:
PMC4414320
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ohanian M
,
Kantarjian HM
, Quintas-Cardama A,
Jabbour E
, Abruzzo L,
Verstovsek S
,
Borthakur G
, Ravandi F,
Garcia-Manero G
,
Champlin R
, Pierce S, Alattar ML, Trinh LX,
Luthra R
,
Ferrajoli A
,
Kadia T
, O'Brien S,
Cortes JE
. Tyrosine kinase inhibitors as initial therapy for patients with chronic myeloid leukemia in accelerated phase. Clin Lymphoma Myeloma Leuk. 2014 Apr; 14(2):155-162.e1.
PMID:
24332214
; PMCID:
PMC3959284
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Jabbour E
, Ghanem H,
Huang X
, Ravandi F,
Garcia-Manero G
, O'Brien S, Faderl S, Pierce S, Choi S,
Verstovsek S
, Brandt M,
Cortes J
,
Kantarjian H
. Acute myeloid leukemia after myelodysplastic syndrome and failure of therapy with hypomethylating agents: an emerging entity with a poor prognosis. Clin Lymphoma Myeloma Leuk. 2014 Apr; 14(2):93-7.
PMID:
24447728
; PMCID:
PMC4098769
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Foran J, Ravandi F,
Wierda W
,
Garcia-Manero G
,
Verstovsek S
,
Kadia T
, Burger J, Yule M, Langford G, Lyons J, Ayrton J, Lock V,
Borthakur G
,
Cortes J
,
Kantarjian H
. A phase I and pharmacodynamic study of AT9283, a small-molecule inhibitor of aurora kinases in patients with relapsed/refractory leukemia or myelofibrosis. Clin Lymphoma Myeloma Leuk. 2014 Jun; 14(3):223-30.
PMID:
24355079
; PMCID:
PMC4096861
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Arana Yi C, Jeyakumar G, Medina P, Cortes J, Pierce S,
Bueso-Ramos C
,
Kantarjian H
,
Verstovsek S
. Discrepancy in diagnosis of primary myelofibrosis between referral and tertiary care centers. Leuk Res. 2014 Jan; 38(1):91-4.
PMID:
24284333
; PMCID:
PMC4406374
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Jain N
,
Khoury JD
,
Pemmaraju N
, Kollipara P,
Kantarjian H
,
Verstovsek S
. Imatinib therapy in a patient with suspected chronic neutrophilic leukemia and FIP1L1-PDGFRA rearrangement. Blood. 2013 Nov 07; 122(19):3387-8.
PMID:
24203930
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Fu B, Jaso JM, Sargent RL, Goswami M,
Verstovsek S
,
Medeiros LJ
, Wang SA. Bone marrow fibrosis in patients with primary myelodysplastic syndromes has prognostic value using current therapies and new risk stratification systems. Mod Pathol. 2014 May; 27(5):681-9.
PMID:
24186132
.
Citations:
17
Fields:
Pat
Pathology
Translation:
Humans
Talpaz M, Paquette R, Afrin L, Hamburg SI, Prchal JT, Jamieson K, Terebelo HR, Ortega GL, Lyons RM, Tiu RV, Winton EF, Natrajan K, Odenike O, Claxton D, Peng W, O'Neill P, Erickson-Viitanen S, Leopold L, Sandor V, Levy RS,
Kantarjian HM
,
Verstovsek S
. Interim analysis of safety and efficacy of ruxolitinib in patients with myelofibrosis and low platelet counts. J Hematol Oncol. 2013 Oct 29; 6(1):81.
PMID:
24283202
; PMCID:
PMC4176265
.
Citations:
33
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Harrison C, Mesa R, Ross D, Mead A, Keohane C, Gotlib J,
Verstovsek S
. Practical management of patients with myelofibrosis receiving ruxolitinib. Expert Rev Hematol. 2013 Oct; 6(5):511-23.
PMID:
24083419
; PMCID:
PMC8201600
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Takahashi K
,
Patel KP
,
Kantarjian H
,
Luthra R
, Pierce S,
Cortes J
,
Verstovsek S
. JAK2 p.V617F detection and allele burden measurement in peripheral blood and bone marrow aspirates in patients with myeloproliferative neoplasms. Blood. 2013 Nov 28; 122(23):3784-6.
PMID:
24068492
; PMCID:
PMC3952679
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Yilmaz M,
Kantarjian H
,
Jabbour E
, O'Brien S,
Borthakur G
,
Verstovsek S
,
Garcia-Manero G
, Ravandi F, Burger J, Pierce S, Quintas-Cardama A,
Cortes J
. Similar outcome of patients with chronic myeloid leukemia treated with imatinib in or out of clinical trials. Clin Lymphoma Myeloma Leuk. 2013 Dec; 13(6):693-9.
PMID:
24060289
; PMCID:
PMC3835390
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Vaddi K, Erickson-Viitanen S, Sun W, Sandor V,
Kantarjian HM
. Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I. Haematologica. 2013 Dec; 98(12):1865-71.
PMID:
24038026
; PMCID:
PMC3856961
.
Citations:
71
Fields:
Hem
Hematology
Translation:
Humans
Falchi L,
Kantarjian HM
, Wang X, Verma D, O'Brien S,
Jabbour EJ
,
Ravandi-Kashani F
,
Borthakur G
,
Garcia-Manero G
,
Verstovsek S
,
Burger JA
,
Luthra R
,
Cortes JE
, Quint?s-Cardama A. Significance of deeper molecular responses in patients with chronic myeloid leukemia in early chronic phase treated with tyrosine kinase inhibitors. Am J Hematol. 2013 Dec; 88(12):1024-9.
PMID:
23913852
; PMCID:
PMC3849405
.
Citations:
28
Fields:
Hem
Hematology
Translation:
Humans
Cherry M, Cardenas-Turanzas M, Pham H,
Kantarjian H
,
Cortes J
, Pierce S, Zhou L,
Verstovsek S
. Patients with polycythemia vera and essential thrombocythemia with prior malignancy do not have significantly worse outcome. Leuk Res. 2013 Nov; 37(11):1472-6.
PMID:
23993426
; PMCID:
PMC3818458
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Sampath D, Malik A, Plunkett W, Nowak B, Williams B, Burton M,
Verstovsek S
, Faderl S,
Garcia-Manero G
, List AF, Sebti S,
Kantarjian HM
, Ravandi F, Lancet JE. Phase I clinical, pharmacokinetic, and pharmacodynamic study of the Akt-inhibitor triciribine phosphate monohydrate in patients with advanced hematologic malignancies. Leuk Res. 2013 Nov; 37(11):1461-7.
PMID:
23993427
; PMCID:
PMC4205589
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Verstovsek S
. Tips on using ruxolitinib in everyday practice as therapy for myelofibrosis. Leuk Lymphoma. 2014 Jan; 55(1):5-6.
PMID:
23829281
; PMCID:
PMC4916492
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Mesa RA, Kiladjian JJ,
Verstovsek S
, Al-Ali HK, Gotlib J, Gisslinger H, Levy R, Siulnik A, Gupta V, Khan M, DiPersio JF, McQuitty M, Catalano JV, Hunter DS, Knoops L, Deininger M, Cervantes F, Miller C, Vannucchi AM, Silver RT, Barbui T, Talpaz M, Barosi G, Winton EF, Mendeson E, Harvey JH, Arcasoy MO, Hexner E, Lyons RM, Paquette R, Raza A, Sun W, Sandor V,
Kantarjian HM
, Harrison C. Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies. Haematologica. 2014 Feb; 99(2):292-8.
PMID:
23911705
; PMCID:
PMC3912959
.
Citations:
20
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Daver N
, Shastri A,
Kadia T
, Quintas-Cardama A,
Jabbour E
,
Konopleva M
, O'Brien S, Pierce S, Zhou L,
Cortes J
,
Kantarjian H
,
Verstovsek S
. Modest activity of pomalidomide in patients with myelofibrosis and significant anemia. Leuk Res. 2013 Nov; 37(11):1440-4.
PMID:
23890523
; PMCID:
PMC4232180
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jain P,
Lin P
,
Bueso-Ramos C
,
Verstovsek S
,
Pemmaraju N
. Primary autoimmune myelofibrosis (MF) with high-grade peripheral T-cell lymphoma (PTCL) NOS. Eur J Haematol. 2013 Oct; 91(4):378-9.
PMID:
23772772
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Tefferi A, Cervantes F, Mesa R, Passamonti F,
Verstovsek S
, Vannucchi AM, Gotlib J, Dupriez B, Pardanani A, Harrison C, Hoffman R, Gisslinger H, Thiele J, Barbui T, Barosi G, Kr?ger N. Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report. Blood. 2013 Aug 22; 122(8):1395-8.
PMID:
23838352
; PMCID:
PMC4828070
.
Citations:
114
Fields:
Hem
Hematology
Translation:
Humans
Verstovsek S
. Ruxolitinib for myelofibrosis: from 'palliation' to prolongation of survival. Oncology (Williston Park). 2013 Jul; 27(7):717-8.
PMID:
23977769
; PMCID:
PMC4821411
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Mesa RA, Silver RT,
Verstovsek S
, Mascarenhas J, Kessler CM, Rondelli D, Goldberg JD, Marchioli R, Demakos EP, Silverman LR, Hoffman R. Single agent bevacizumab for myelofibrosis: results of the Myeloproliferative Disorders Research Consortium Trial. Haematologica. 2013 Sep; 98(9):1421-3.
PMID:
23812932
; PMCID:
PMC3762099
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Hu S
,
Bueso-Ramos CE
,
Verstovsek S
,
Miranda RN
,
Yin CC
,
McDonnell T
,
Medeiros LJ
,
Lin P
. Metastatic splenic angiosarcoma presenting with thrombocytopenia and bone marrow fibrosis mimicking idiopathic thrombocytopenic purpura and primary myelofibrosis: a diagnostic challenge. Clin Lymphoma Myeloma Leuk. 2013 Oct; 13(5):629-33.
PMID:
23800601
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Abdel-Wahab O, Manshouri T, Kilpivaara O,
Cortes J
, Roupie AL, Zhang SJ, Harris D,
Estrov Z
,
Kantarjian H
, Levine RL,
Verstovsek S
, Quint?s-Cardama A. Molecular analysis of patients with polycythemia vera or essential thrombocythemia receiving pegylated interferon a-2a. Blood. 2013 Aug 08; 122(6):893-901.
PMID:
23782935
; PMCID:
PMC3739035
.
Citations:
87
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Eghtedar A,
Kantarjian H
,
Jabbour E
, O'Brien S, Burton E,
Garcia-Manero G
,
Verstovsek S
, Ravandi F,
Borthakur G
,
Konopleva M
, Quintas-Cardama A,
Cortes J
. Outcome after failure of second generation tyrosine kinase inhibitors treatment as first-line therapy for patients with chronic myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2013 Aug; 13(4):477-84.
PMID:
23770156
; PMCID:
PMC3752280
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Daver N, Vega-Ruiz A,
Kantarjian HM
,
Estrov Z
,
Ferrajoli A
,
Kornblau S
,
Verstovsek S
,
Garcia-Manero G
, Cortes JE. A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome. Eur J Cancer Care (Engl). 2013 Sep; 22(5):605-11.
PMID:
23701251
; PMCID:
PMC3745781
.
Citations:
8
Fields:
Neo
Neoplasms
Nur
Nursing
Translation:
Humans
CT
Clinical Trials
Mesa RA, Shields A, Hare T, Erickson-Viitanen S, Sun W, Sarlis NJ, Sandor V, Levy RS,
Verstovsek S
. Progressive burden of myelofibrosis in untreated patients: assessment of patient-reported outcomes in patients randomized to placebo in the COMFORT-I study. Leuk Res. 2013 Aug; 37(8):911-6.
PMID:
23684482
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Santos FP, Tam CS,
Kantarjian H
,
Cortes J
, Thomas D, Pollock R,
Verstovsek S
. Splenectomy in patients with myeloproliferative neoplasms: efficacy, complications and impact on survival and transformation. Leuk Lymphoma. 2014 Jan; 55(1):121-7.
PMID:
23573823
; PMCID:
PMC3874259
.
Citations:
14
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Fu B,
Ok CY
, Goswami M, Xei W, Jaso JM,
Muzzafar T
,
Bueso-Ramos C
,
Verstovsek S
,
Garcia-Manero G
,
Medeiros LJ
,
Wang SA
. The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related myelodysplastic syndromes. Ann Hematol. 2013 Oct; 92(10):1335-43.
PMID:
23660629
; PMCID:
PMC4190057
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Jain P,
Kantarjian H
, Nazha A, O'Brien S,
Jabbour E
, Romo CG, Pierce S, Cardenas-Turanzas M,
Verstovsek S
,
Borthakur G
, Ravandi F,
Cortes J
, Quint?s-Cardama A. Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: results with four tyrosine kinase inhibitor modalities. Blood. 2013 Jun 13; 121(24):4867-74.
PMID:
23620574
; PMCID:
PMC3743466
.
Citations:
51
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Sever M, Pierce S, Zhou L,
Kantarjian H
,
Verstovsek S
, Quint?s-Cardama A. Significance of cytogenetic abnormalities in patients with polycythemia vera. Leuk Lymphoma. 2013 Dec; 54(12):2667-70.
PMID:
23488603
; PMCID:
PMC3815965
.
Citations:
10
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Barosi G, Mesa R, Finazzi G, Harrison C, Kiladjian JJ, Lengfelder E, McMullin MF, Passamonti F, Vannucchi AM, Besses C, Gisslinger H, Samuelsson J,
Verstovsek S
, Hoffman R, Pardanani A, Cervantes F, Tefferi A, Barbui T. Revised response criteria for polycythemia vera and essential thrombocythemia: an ELN and IWG-MRT consensus project. Blood. 2013 Jun 06; 121(23):4778-81.
PMID:
23591792
; PMCID:
PMC3674675
.
Citations:
85
Fields:
Hem
Hematology
Translation:
Humans
Collier P,
Patel K
, Waeltz P, Rupar M,
Luthra R
, Liu PC, Hollis G, Huber R,
Verstovsek S
, Burn TC. Validation of standards for quantitative assessment of JAK2 c.1849G>T (p.V617F) allele burden analysis in clinical samples. Genet Test Mol Biomarkers. 2013 May; 17(5):429-37.
PMID:
23537216
; PMCID:
PMC4696442
.
Citations:
6
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Verstovsek S
, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger M, Miller C, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner E, Lyons RM, Paquette R, Raza A, Vaddi K, Erickson-Viitanen S, Sun W, Sandor V,
Kantarjian HM
. The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis. Br J Haematol. 2013 May; 161(4):508-16.
PMID:
23480528
; PMCID:
PMC4055021
.
Citations:
42
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Santos FP. What is next beyond janus kinase 2 inhibitors for primary myelofibrosis? Curr Opin Hematol. 2013 Mar; 20(2):123-9.
PMID:
23385614
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Wang SA
, Hutchinson L,
Tang G
, Chen SS, Miron PM,
Huh YO
, Jones DM,
Bueso-Ramos C
,
Verstovsek S
,
Medeiros LJ
,
Miranda RN
. Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components. Am J Hematol. 2013 Mar; 88(3):219-24.
PMID:
23440662
; PMCID:
PMC4188390
.
Citations:
26
Fields:
Hem
Hematology
Translation:
Humans
Cells
Fiskus W
,
Verstovsek S
, Manshouri T, Smith JE, Peth K, Abhyankar S, McGuirk J,
Bhalla KN
. Dual PI3K/AKT/mTOR inhibitor BEZ235 synergistically enhances the activity of JAK2 inhibitor against cultured and primary human myeloproliferative neoplasm cells. Mol Cancer Ther. 2013 May; 12(5):577-88.
PMID:
23445613
.
Citations:
61
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Tam CS,
Verstovsek S
. Investigational Janus kinase inhibitors. Expert Opin Investig Drugs. 2013 Jun; 22(6):687-99.
PMID:
23432430
.
Citations:
17
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Cells
Nazha A,
Estrov Z
,
Cortes J
,
Bueso-Ramos CE
,
Kantarjian H
,
Verstovsek S
. Prognostic implications and clinical characteristics associated with bone marrow fibrosis in patients with myelofibrosis. Leuk Lymphoma. 2013 Nov; 54(11):2537-9.
PMID:
23343175
; PMCID:
PMC4135587
.
Citations:
6
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Mesa RA, Gotlib J, Gupta V, Catalano JV, Deininger MW, Shields AL, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Hare T, Erickson-Viitanen S, Sun W, Sandor V, Levy RS,
Kantarjian HM
,
Verstovsek S
. Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial. J Clin Oncol. 2013 Apr 01; 31(10):1285-92.
PMID:
23423753
; PMCID:
PMC4979167
.
Citations:
81
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Quint?s-Cardama A. Molecular pathways: Jak/STAT pathway: mutations, inhibitors, and resistance. Clin Cancer Res. 2013 Apr 15; 19(8):1933-40.
PMID:
23406773
; PMCID:
PMC5021219
.
Citations:
132
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Takahashi K
,
Cortes J
, Pierce S, Abruzzo L,
Kantarjian H
,
Verstovsek S
. Chromosome 5q deletion is extremely rare in patients with myelofibrosis. Leuk Res. 2013 May; 37(5):552-5.
PMID:
23391517
; PMCID:
PMC4408989
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Kantarjian H
, Pierce S,
Cortes J
,
Verstovsek S
, Quint?s-Cardama A. Prognostic model to identify patients with myelofibrosis at the highest risk of transformation to acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):315-318.e2.
PMID:
23391717
; PMCID:
PMC3901422
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
. Advanced systemic mastocytosis: the impact of KIT mutations in diagnosis, treatment, and progression. Eur J Haematol. 2013 Feb; 90(2):89-98.
PMID:
23181448
; PMCID:
PMC3761194
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Cells
Sever M,
Cortes J
,
Kantarjian H
,
Verstovsek S
, Quint?s-Cardama A. Bone marrow mast cell burden and serum tryptase level as markers of response in patients with systemic mastocytosis. Leuk Lymphoma. 2013 Sep; 54(9):1959-64.
PMID:
23278641
; PMCID:
PMC5127201
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Gotlib J, Pardanani A, Akin C, Reiter A, George T, Hermine O, Kluin-Nelemans H, Hartmann K, Sperr WR, Brockow K, Schwartz LB, Orfao A, Deangelo DJ, Arock M, Sotlar K, Horny HP, Metcalfe DD, Escribano L,
Verstovsek S
, Tefferi A, Valent P. International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) & European Competence Network on Mastocytosis (ECNM) consensus response criteria in advanced systemic mastocytosis. Blood. 2013 Mar 28; 121(13):2393-401.
PMID:
23325841
; PMCID:
PMC3612852
.
Citations:
38
Fields:
Hem
Hematology
Translation:
Humans
Verstovsek S
. Ruxolitinib: an oral Janus kinase 1 and Janus kinase 2 inhibitor in the management of myelofibrosis. Postgrad Med. 2013 Jan; 125(1):128-35.
PMID:
23391678
; PMCID:
PMC5025038
.
Citations:
17
Fields:
Med
Medicine (General)
Translation:
Humans
Lee HJ
,
Daver N
,
Kantarjian HM
,
Verstovsek S
, Ravandi F. The role of JAK pathway dysregulation in the pathogenesis and treatment of acute myeloid leukemia. Clin Cancer Res. 2013 Jan 15; 19(2):327-35.
PMID:
23209034
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Atallah E,
Verstovsek S
. Emerging drugs for myelofibrosis. Expert Opin Emerg Drugs. 2012 Dec; 17(4):555-70.
PMID:
23186315
; PMCID:
PMC5009610
.
Citations:
3
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Komrokji R,
Verstovsek S
. Assessing efficacy in myelofibrosis treatment: a focus on JAK inhibition. Expert Rev Hematol. 2012 Dec; 5(6):631-41.
PMID:
23216593
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Greaves WO, Verma S, Bisrat T, Strati P, Rahimi H, Paladugu AV,
Luthra R
,
Patel KP
,
Medeiros LJ
, Yao H, Pierce S,
Bueso-Ramos CE
,
Verstovsek S
. TP53 mutation is rare in primary myelofibrosis. Leuk Lymphoma. 2013 Jul; 54(7):1552.
PMID:
23121011
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Strati P,
Cortes J
, Faderl S,
Kantarjian H
,
Verstovsek S
. Long-term follow-up of patients with hypereosinophilic syndrome treated with Alemtuzumab, an anti-CD52 antibody. Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):287-91.
PMID:
23123105
; PMCID:
PMC4445419
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Santos FP. JAK2 inhibitors for myelofibrosis: why are they effective in patients with and without JAK2V617F mutation? Anticancer Agents Med Chem. 2012 Nov; 12(9):1098-109.
PMID:
22583424
.
Citations:
12
Fields:
Ant
Antineoplastic Agents
Che
Chemistry
Translation:
Humans
Animals
Komrokji RS,
Verstovsek S
, Padron E, List AF. Advances in the management of myelofibrosis. Cancer Control. 2012 Oct; 19(4 Suppl):4-15.
PMID:
23042420
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Benjamini O, Jain P,
Estrov Z
,
Kantarjian HM
,
Verstovsek S
. Therapeutic effects of ruxolitinib in patients with myelofibrosis without clinically significant splenomegaly. Blood. 2012 Sep 27; 120(13):2768-9.
PMID:
23019204
; PMCID:
PMC4081400
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Jain P,
Verstovsek S
,
Orlowski RZ
, Yap E,
Amin HM
. An unusual case of aggressive systemic mastocytosis with associated refractory plasma cell myeloma. Clin Lymphoma Myeloma Leuk. 2012 Dec; 12(6):459-62.
PMID:
23009979
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A,
Estrov Z
, Ebert BL, Chiosis G, Nimer SD, Bernstein BE,
Verstovsek S
, Levine RL, G?nen M. Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy. Nature. 2012 Sep 06; 489(7414):155-9.
PMID:
22820254
; PMCID:
PMC3991463
.
Citations:
149
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Santos FP,
Verstovsek S
. Therapy with JAK2 inhibitors for myeloproliferative neoplasms. Hematol Oncol Clin North Am. 2012 Oct; 26(5):1083-99.
PMID:
23009939
; PMCID:
PMC4406395
.
Citations:
10
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Randhawa J, Ostojic A, Vrhovac R, Atallah E,
Verstovsek S
. Splenomegaly in myelofibrosis--new options for therapy and the therapeutic potential of Janus kinase 2 inhibitors. J Hematol Oncol. 2012 Aug 01; 5:43.
PMID:
22852872
; PMCID:
PMC3464878
.
Citations:
16
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cheng X, Golemovic M, Zingaro R, Gao MZ, Freireich EJ,
Andreeff M
,
Kantarjian HM
,
Verstovsek S
, Quint?s-Cardama A. The organic arsenic derivative GMZ27 induces PML-RARa-independent apoptosis in myeloid leukemia cells. Anticancer Res. 2012 Jul; 32(7):2871-80.
PMID:
22753750
; PMCID:
PMC5166574
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Verstovsek S
,
Kantarjian HM
,
Estrov Z
,
Cortes JE
, Thomas DA,
Kadia T
, Pierce S,
Jabbour E
,
Borthakur G
, Rumi E, Pungolino E, Morra E, Caramazza D, Cazzola M, Passamonti F. Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls. Blood. 2012 Aug 09; 120(6):1202-9.
PMID:
22718840
; PMCID:
PMC4081158
.
Citations:
82
Fields:
Hem
Hematology
Translation:
Humans
Kantarjian H
,
Estrov Z
,
Borthakur G
,
Cortes J
,
Verstovsek S
, Quint?s-Cardama A. Therapy with the histone deacetylase inhibitor pracinostat for patients with myelofibrosis. Leuk Res. 2012 Sep; 36(9):1124-7.
PMID:
22475363
; PMCID:
PMC4152772
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Verstovsek S
, Santos FP. Breakthroughs in myeloproliferative neoplasms. Hematology. 2012 Apr; 17 Suppl 1:S55-8.
PMID:
22507780
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Harrison C,
Verstovsek S
, McMullin MF, Mesa R. Janus kinase inhibition and its effect upon the therapeutic landscape for myelofibrosis: from palliation to cure? Br J Haematol. 2012 May; 157(4):426-37.
PMID:
22463737
; PMCID:
PMC8721529
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Zhang SJ, Rampal R, Manshouri T, Patel J, Mensah N, Kayserian A, Hricik T, Heguy A, Hedvat C,
Kantarjian H
, Levine RL, Abdel-Wahab O,
Verstovsek S
, G?nen M. Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome. Blood. 2012 May 10; 119(19):4480-5.
PMID:
22431577
; PMCID:
PMC3362363
.
Citations:
95
Fields:
Hem
Hematology
Translation:
Humans
Cells
Eghtedar A,
Verstovsek S
,
Estrov Z
,
Burger J
,
Cortes J
, Bivins C, Faderl S,
Ferrajoli A
,
Borthakur G
, George S, Scherle PA, Newton RC,
Kantarjian HM
, Ravandi F. Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia. Blood. 2012 May 17; 119(20):4614-8.
PMID:
22422826
; PMCID:
PMC4081383
.
Citations:
85
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Ohanian M
, Leventaki V,
Verstovsek S
,
Estrov Z
,
Lin P
,
Yin C
,
Kantarjian H
,
Huh Y
, Ravandi F. Acute lymphoblastic leukemia arising in post-polycythemic myelofibrosis: a rare entity. Leuk Lymphoma. 2012 Sep; 53(9):1839-41.
PMID:
22303899
; PMCID:
PMC4120044
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger M, Miller C, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner E, Lyons RM, Paquette R, Raza A, Vaddi K, Erickson-Viitanen S, Koumenis IL, Sun W, Sandor V,
Kantarjian HM
. A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med. 2012 Mar 01; 366(9):799-807.
PMID:
22375971
; PMCID:
PMC4822164
.
Citations:
737
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Ostojic A, Vrhovac R,
Verstovsek S
. Ruxolitinib for the treatment of myelofibrosis: its clinical potential. Ther Clin Risk Manag. 2012; 8:95-103.
PMID:
22399854
; PMCID:
PMC3295626
.
Citations:
14
Gale RP, Barosi G, Barbui T, Cervantes F, Dohner K, Dupriez B, Gupta V, Harrison C, Hoffman R, Kiladjian JJ, Mesa R, Mc Mullin MF, Passamonti F, Ribrag V, Roboz G, Saglio G, Vannucchi A,
Verstovsek S
. RBC-transfusion guidelines update. Leuk Res. 2012 May; 36(5):659-60.
PMID:
22336392
; PMCID:
PMC8162055
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
. Ruxolitinib: the first agent approved for myelofibrosis. Clin Adv Hematol Oncol. 2012 Feb; 10(2):111-3.
PMID:
22402352
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Pemmaraju N
,
Kantarjian H
, Shan J,
Jabbour E
, Quintas-Cardama A,
Verstovsek S
, Ravandi F,
Wierda W
, O'Brien S,
Cortes J
. Analysis of outcomes in adolescents and young adults with chronic myelogenous leukemia treated with upfront tyrosine kinase inhibitor therapy. Haematologica. 2012 Jul; 97(7):1029-35.
PMID:
22271898
; PMCID:
PMC3396674
.
Citations:
31
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Mascarenhas J, Mughal TI,
Verstovsek S
. Biology and clinical management of myeloproliferative neoplasms and development of the JAK inhibitor ruxolitinib. Curr Med Chem. 2012; 19(26):4399-413.
PMID:
22830345
; PMCID:
PMC3480698
.
Citations:
30
Fields:
Che
Chemistry
Translation:
Humans
Cells
Verstovsek S
. Therapeutic advances in myeloproliferative neoplasms: the role of new-small molecule inhibitors. Am Soc Clin Oncol Educ Book. 2012; 406-10.
PMID:
24451772
.
Citations:
Fields:
Neo
Neoplasms
Ostojic A, Vrhovac R,
Verstovsek S
. Ruxolitinib for the treatment of myelofibrosis. Drugs Today (Barc). 2011 Nov; 47(11):817-27.
PMID:
22146225
.
Citations:
1
Fields:
Dru
Drug Therapy
Translation:
Humans
Fiskus W
,
Verstovsek S
, Manshouri T, Rao R, Balusu R, Venkannagari S, Rao NN, Ha K, Smith JE, Hembruff SL, Abhyankar S, McGuirk J,
Bhalla KN
. Heat shock protein 90 inhibitor is synergistic with JAK2 inhibitor and overcomes resistance to JAK2-TKI in human myeloproliferative neoplasm cells. Clin Cancer Res. 2011 Dec 01; 17(23):7347-58.
PMID:
21976548
; PMCID:
PMC3743080
.
Citations:
56
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ostojic A, Vrhovac R,
Verstovsek S
. Ruxolitinib: a new JAK1/2 inhibitor that offers promising options for treatment of myelofibrosis. Future Oncol. 2011 Sep; 7(9):1035-43.
PMID:
21919691
; PMCID:
PMC5147419
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Verma D,
Kantarjian H
, Strom SS, Rios MB,
Jabbour E
, Quintas-Cardama A,
Verstovsek S
, Ravandi F, O'Brien S,
Cortes J
. Malignancies occurring during therapy with tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML) and other hematologic malignancies. Blood. 2011 Oct 20; 118(16):4353-8.
PMID:
21846902
; PMCID:
PMC3291487
.
Citations:
34
Fields:
Hem
Hematology
Translation:
Humans
Cortes J
, Quintas-Cardama A,
Jabbour E
, O'Brien S,
Verstovsek S
,
Borthakur G
, Ravandi F,
Garcia-Manero G
, Burton E, Shan J,
Kantarjian H
. The clinical significance of achieving different levels of cytogenetic response in patients with chronic phase chronic myeloid leukemia after failure to front-line therapy: is complete cytogenetic response the only desirable endpoint? Clin Lymphoma Myeloma Leuk. 2011 Oct; 11(5):421-6.
PMID:
21831744
; PMCID:
PMC3215673
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Quint?s-Cardama A. Spleen deflation and beyond: the pros and cons of Janus kinase 2 inhibitor therapy for patients with myeloproliferative neoplasms. Cancer. 2012 Feb 15; 118(4):870-7.
PMID:
21766300
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Jain N
,
Verstovsek S
, Quint?s-Cardama A. Advances and controversies in the diagnosis, pathogenesis, and treatment of systemic mastocytosis. Cancer. 2011 Dec 15; 117(24):5439-49.
PMID:
21692073
; PMCID:
PMC4839285
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Naqvi K
,
Verstovsek S
,
Kantarjian H
, Ravandi F. A potential role of ruxolitinib in leukemia. Expert Opin Investig Drugs. 2011 Aug; 20(8):1159-66.
PMID:
21635221
; PMCID:
PMC4143907
.
Citations:
7
Fields:
Dru
Drug Therapy
Translation:
Humans
Cells
Jabbour E
, Thomas D,
Kantarjian H
, Zhou L, Pierce S,
Cortes J
,
Verstovsek S
. Comparison of thalidomide and lenalidomide as therapy for myelofibrosis. Blood. 2011 Jul 28; 118(4):899-902.
PMID:
21622644
; PMCID:
PMC4186644
.
Citations:
25
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Freireich EJ,
Kantarjian H
,
Verstovsek S
, Cort?s JE. Retrospect of hematologic malignancies 2010. Clin Lymphoma Myeloma Leuk. 2011 Jun; 11 Suppl 1:S1.
PMID:
22035736
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Santos FP. JAK2 inhibitors: are they the solution? Clin Lymphoma Myeloma Leuk. 2011 Jun; 11 Suppl 1:S28-36.
PMID:
22035745
; PMCID:
PMC4445410
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
, Quint?s-Cardama A. New JAK2 inhibitors for myeloproliferative neoplasms. Expert Opin Investig Drugs. 2011 Jul; 20(7):961-72.
PMID:
21521147
.
Citations:
4
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Cells
Kantarjian H
, Shan J,
Jabbour E
, Abruzzo LV,
Verstovsek S
,
Garcia-Manero G
, O'Brien S,
Cortes J
, Quint?s-Cardama A. Prognostic impact of deletions of derivative chromosome 9 in patients with chronic myelogenous leukemia treated with nilotinib or dasatinib. Cancer. 2011 Nov 15; 117(22):5085-93.
PMID:
21523765
; PMCID:
PMC4324753
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Manshouri T,
Estrov Z
,
Burger J
, Zhang Y, Livun A, Knez L, Harris D,
Creighton CJ
,
Kantarjian HM
,
Verstovsek S
, Quint?s-Cardama A. Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor. Cancer Res. 2011 Jun 01; 71(11):3831-40.
PMID:
21512135
; PMCID:
PMC4067142
.
Citations:
49
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Mesa RA,
Kantarjian H
, Tefferi A, Dueck A, Levy R, Vaddi K, Erickson-Viitanen S, Thomas DA,
Cortes J
,
Borthakur G
, Pardanani AD,
Estrov Z
,
Verstovsek S
. Evaluating the serial use of the Myelofibrosis Symptom Assessment Form for measuring symptomatic improvement: performance in 87 myelofibrosis patients on a JAK1 and JAK2 inhibitor (INCB018424) clinical trial. Cancer. 2011 Nov 01; 117(21):4869-4877.
PMID:
21480207
; PMCID:
PMC4160798
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Vig