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FUNDA MERIC-BERNSTAM
Title
Professor
Institution
MD Anderson
Department
Investigational Cancer Therapeutics
Address
1400 Holcombe Blvd
Houston TX 77030-4008
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Piha-Paul SA
, Tseng C, Leung CH,
Yuan Y
,
Karp DD
,
Subbiah V
,
Hong D
, Fu S,
Naing A
, Rodon J,
Javle M
,
Ajani JA
,
Raghav KP
,
Somaiah N
,
Mills GB
,
Tsimberidou AM
, Zheng X, Chen K,
Meric-Bernstam F
. Phase II study of talazoparib in advanced cancers with BRCA1/2, DNA repair, and PTEN alterations. NPJ Precis Oncol. 2024 Jul 31; 8(1):166.
PMID:
39085400
; PMCID:
PMC11291882
.
Citations:
Curigliano G, Jimenez MM, Shimizu T, Keam B,
Meric-Bernstam F
, Rutten A, Glaspy J, Schuler PJ, Parikh NS, Ising M, Hassounah N, Wu J, Leyk M, Chen X, Burks H, Chaudhury A, Otero J, Cabanas EG. A phase I trial of LHC165 single agent and in combination with spartalizumab in patients with advanced solid malignancies. ESMO Open. 2024 Aug; 9(8):103643.
PMID:
39088985
; PMCID:
PMC11345372
.
Citations:
Son J, Zhang Y, Lin H, Mirallas O, Alvarez Ballesteros P, Nardo M, Clark N, Hillman RT, Campbell E, Holla V, Johnson AM, Biter AB, Yuan Y, Cobb LP, Gershenson DM, Jazaeri AA, Lu KH,
Soliman PT
,
Westin SN
,
Euscher ED
, Lawson BC, Yang RK, Meric-Bernstam F, Hong DS, Son J, Zhang Y, Lin H, Mirallas O, Alvarez Ballesteros P, Nardo M, Clark N, Hillman RT, Campbell E, Holla V, Johnson AM, Biter AB,
Yuan Y
, Cobb LP, Gershenson DM,
Jazaeri AA
,
Lu KH
, Soliman PT, Westin SN, Euscher ED, Lawson BC, Yang RK,
Meric-Bernstam F
,
Hong DS
. Clinical and Genomic Landscape of RAS Mutations in Gynecologic Cancers. Clin Cancer Res. 2024 Jul 15; 30(14):2986-2995.
PMID:
38687597
; PMCID:
PMC11250057
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
White BS, Woo XY, Koc S, Sheridan T, Neuhauser SB, Wang S, Evrard YA, Chen L, Foroughi Pour A, Landua JD, Mashl RJ, Davies SR, Fang B, Rosa MG, Evans KW, Bailey MH, Chen Y, Xiao M, Rubinstein JC, Sanderson BJ, Lloyd MW, Domanskyi S, Dobrolecki LE, Fujita M,
Fujimoto J
, Xiao G, Fields RC, Mudd JL, Xu X, Hollingshead MG, Jiwani S, Acevedo S, PDXNet Consortium, Davis-Dusenbery BN, Robinson PN, Moscow JA, Doroshow JH, Mitsiades N, Kaochar S, Pan CX, Carvajal-Carmona LG, Welm AL, Welm BE, Govindan R, Li S, Davies MA,
Roth JA
,
Meric-Bernstam F
, Xie Y, Herlyn M, Ding L, Lewis MT, Bult CJ, Dean DA, Chuang JH, Raso MG. A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis. Cancer Res. 2024 07 02; 84(13):2060-2072.
PMID:
39082680
; PMCID:
PMC11217732
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Meric-Bernstam F, Lloyd MW, Koc S, Evrard YA, McShane LM, Lewis MT, Evans KW, Li D, Rubinstein LV, Welm AL, Dean DA, Srivastava A, Grover JW,
Ha MJ
, Chen H, Huang X, Varadarajan K, Wang J, Roth JA, Welm BE, Govindan R, Ding L, Kaochar S, Mitsiades N, Carvajal-Carmona LG, Herlyn M, Davies MA, Shapiro GI, Fields RC, Trevino JG, Harrell JC, Doroshow JH, Chuang JH, Moscow JA,
Meric-Bernstam F
, Lloyd MW, Koc S, Evrard YA, McShane LM, Lewis MT, Evans KW, Li D, Rubinstein L, Welm A, Dean DA, Srivastava A, Grover JW, Ha MJ, Chen H, Huang X, Varadarajan K, Wang J,
Roth JA
, Welm B, Govinden R, Ding L, Kaochar S, Mitsiades N, Carvajal-Carmona L, Herylyn M, Davies MA, Shapiro GI, Fields R, Trevino JG, Harrell JC, NCI PDXNet Consortium, Doroshow JH, Chuang JH, Moscow JA. Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Mol Cancer Ther. 2024 Jul 02; 23(7):924-938.
PMID:
38641411
; PMCID:
PMC11217730
.
Citations:
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Schuetze S, Rothe M, Mangat PK, Garrett-Mayer E,
Meric-Bernstam F
, Calfa CJ, Farrington LC, Livingston MB, Wentzel K, Behl D, Kier Y, Marr AS, von Mehren M, Press JZ, Thota R, Grantham GN, Gregory A, Hinshaw DC, Halabi S, Schilsky RL. Palbociclib in Patients With Soft Tissue Sarcoma With CDK4 Amplifications: Results From the Targeted Agent and Profiling Utilization Registry Study. JCO Precis Oncol. 2024 Jul; 8:e2400219.
PMID:
39013131
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Goyal L,
Meric-Bernstam F
, Hollebecque A, Valle JW, Morizane C, Karasic TB, Abrams TA, Furuse J, Kelley RK, Cassier PA, Kl?mpen HJ, Chang HM, Chen LT, Tabernero J, Oh DY, Mahipal A, Moehler M, Komatsu Y, Ahn DH, Epstein RS, Halim AB, Wacheck V, He Y, Liu M, Benhadji KA, Bridgewater JA, FOENIX-CCA2 Study Investigators. Plain language summary of the FOENIX-CCA2 study: futibatinib for people with advanced bile duct cancer. Future Oncol. 2024 Jun 17; 1-12.
PMID:
38884254
.
Citations:
Fields:
Neo
Neoplasms
Gouda MA, Shunyakova J, Naing A, Dumbrava E, Hong DS, Yuan Y, Yang P, Myers A, Liang Y, Peng J,
Karp D
,
Tsimberidou AM
, Rodon J, Yap TA, Piha-Paul SA,
Meric-Bernstam F
, Fu S. A phase I study of TAK-659 and paclitaxel in patients with taxane-refractory advanced solid tumors. ESMO Open. 2024 Jun; 9(6):103486.
PMID:
38914452
; PMCID:
PMC11258623
.
Citations:
Translation:
Humans
CT
Clinical Trials
Mosele MF, Westphalen CB, Stenzinger A, Barlesi F, Bayle A, Bi?che I, Bonastre J, Castro E, Dienstmann R, Kr?mer A, Czarnecka AM,
Meric-Bernstam F
, Michiels S, Miller R, Normanno N, Reis-Filho J, Remon J, Robson M, Rouleau E, Scarpa A, Serrano C, Mateo J, Andr? F. Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024: a report from the ESMO Precision Medicine Working Group. Ann Oncol. 2024 Jul; 35(7):588-606.
PMID:
38834388
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Grivas P, Garralda E,
Meric-Bernstam F
, Mellinghoff IK, Goyal L, Harding JJ, Dees EC, Bahleda R, Azad NS, Karippot A, Kurzrock R, Tabernero J, Kononen J, Ng MCH, Mehta R, Uboha NV, Bigot F, Boni V, Bowyer SE, Breder V, Cervantes A, Chan N, Cleary JM, Dhawan M, Eefsen RL, Ewing J, Graham DM, Guren TK, Won Kim J, Koynov K, Oh DY, Redman R, Yen CJ, Spetzler D, Roubaudi-Fraschini MC, Nicolas-Metral V, Ait-Sarkouh R, Zanna C, Ennaji A, Pokorska-Bocci A, Flaherty KT. Evaluating Debio 1347 in Patients with FGFR Fusion-Positive Advanced Solid Tumors from the FUZE Multicenter, Open-Label, Phase II Basket Trial. Clin Cancer Res. 2024 May 21.
PMID:
38771739
.
Citations:
Fields:
Neo
Neoplasms
Raso MG, Barrientos Toro E, Evans K, Rizvi Y, Lazcano R,
Akcakanat A
, Sini P, Trapani F, Madlener EJ, Waldmeier L,
Lazar A
,
Meric-Bernstam F
. Heterogeneous Profile of ROR1 Protein Expression across Tumor Types. Cancers (Basel). 2024 May 15; 16(10).
PMID:
38791952
; PMCID:
PMC11119314
.
Citations:
1
Pilie PG, Giuliani V, Wang WL, McGrail DJ, Bristow CA, Ngoi NYL, Kyewalabye K, Wani KM, Le H, Campbell E, S?nchez NS, Yang D, Gheeya JS, Goswamy RV, Holla V, Shaw KR, Meric-Bernstam F, Liu CY, Ma X, Feng N, Machado AA, Bardenhagen JP, Vellano CP, Marszalek JR, Rajendra E, Piscitello D, Johnson TI, Likhatcheva M, Elinati E, Majithiya J, Neves J, Grinkevich V, Ranzani M, Roy-Luzarraga M, Boursier M, Armstrong L, Geo L, Lillo G, Tse WY, Lazar AJ, Kopetz SE, Geck Do MK, Lively S, Johnson MG, Robinson HMR, Smith GCM, Carroll CL, Di Francesco ME, Jones P, Heffernan TP, Yap TA, Pili? PG, Giuliani V, Wang WL, McGrail DJ, Bristow CA, Ngoi NYL, Kyewalabye K, Wani KM, Le H, Campbell E, Sanchez NS, Yang D, Gheeya JS, Goswamy RV, Holla V, Shaw KR,
Meric-Bernstam F
, Liu CY, Ma X, Feng N, Machado AA, Bardenhagen JP, Vellano CP, Marszalek JR, Rajendra E, Piscitello D, Johnson TI, Likhatcheva M, Elinati E, Majithiya J, Neves J, Grinkevich V, Ranzani M, Luzarraga MR, Boursier M, Armstrong L, Geo L, Lillo G, Tse WY,
Lazar AJ
, Kopetz SE, Geck Do MK, Lively S, Johnson MG, Robinson HMR, Smith GCM, Carroll CL, Di Francesco ME, Jones P, Heffernan TP, Yap TA. Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clin Cancer Res. 2024 May 15; 30(10):2121-2139.
PMID:
38416404
; PMCID:
PMC11094420
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Li BT,
Meric-Bernstam F
, Bardia A, Naito Y, Siena S, Aftimos P, Anderson I, Curigliano G, de Miguel M, Kalra M, Oh DY, Park JO, Postel-Vinay S, Rha SY, Satoh T, Spanggaard I, Michelini F, Smith A, Machado KK, Saura C, DESTINY-PanTumor01 study group. Trastuzumab deruxtecan in patients with solid tumours harbouring specific activating HER2 mutations (DESTINY-PanTumor01): an international, phase 2 study. Lancet Oncol. 2024 Jun; 25(6):707-719.
PMID:
38710187
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Moffat GT, Hu ZI,
Meric-Bernstam F
, Kong EK, Pavlick D, Ross JS, Murugesan K,
Kwong L
, De Armas AD,
Korkut A
,
Javle M
, Knox JJ. KRAS Allelic Variants in Biliary Tract Cancers. JAMA Netw Open. 2024 May 01; 7(5):e249840.
PMID:
38709532
; PMCID:
PMC11074811
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
DiPeri TP, Evans KW, Wang B, Zhao M,
Akcakanat A
, Raso MG, Rizvi YQ, Zheng X,
Korkut A
, Varadarajan K, Uzunparmak B, Dumbrava EE, Pant S,
Ajani JA
, Pohlmann PR, Jensen VB,
Javle M
, Rodon J,
Meric-Bernstam F
, DiPeri TP, Evans KW, Wang B, Zhao M, Akcakanat A, Raso MG, Rizvi YQ, Zheng X, Korkut A, Varadarajan K, Uzunparmak B, Dumbrava EE,
Pant S
, Ajani JA, Pohlmann PR, Jensen VB, Javle M, Rodon J, Meric-Bernstam F. Co-clinical Trial of Novel Bispecific Anti-HER2 Antibody Zanidatamab in Patient-Derived Xenografts. Cancer Discov. 2024 May 01; 14(5):828-845.
PMID:
38358339
; PMCID:
PMC11064988
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
CT
Clinical Trials
Bardia A, Krop IE, Kogawa T, Juric D, Tolcher AW, Hamilton EP, Mukohara T, Lisberg A, Shimizu T, Spira AI, Tsurutani J,
Damodaran S
, Papadopoulos KP, Greenberg J, Kobayashi F, Zebger-Gong H, Wong R, Kawasaki Y, Nakamura T,
Meric-Bernstam F
. Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. J Clin Oncol. 2024 Jul 01; 42(19):2281-2294.
PMID:
38652877
; PMCID:
PMC11210948
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Meric-Bernstam F
, Hollebecque A, Furuse J, Oh DY, Bridgewater JA, Shimura M, Anderson B, Hangai N, Wacheck V, Goyal L. Safety Profile and Adverse Event Management for Futibatinib, An Irreversible FGFR1-4 Inhibitor: Pooled Safety Analysis of 469 Patients. Clin Cancer Res. 2024 Apr 15; 30(8):1466-1477.
PMID:
38329716
; PMCID:
PMC11016890
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Piha-Paul SA
, Xu B, Dumbrava EE,
Fu S
,
Karp DD
,
Meric-Bernstam F
,
Hong DS
, Rodon JA,
Tsimberidou AM
,
Raghav K
,
Ajani JA
,
Conley AP
,
Mott F
, Fan Y, Fan J, Peng P, Wang H, Ni S, Sun C, Qiang X, Levin WJ, Ngo B, Ru QC, Wu F,
Javle MM
. First-In-Human Phase I Study of Tinengotinib (TT-00420), a Multiple Kinase Inhibitor, as a Single Agent in Patients With Advanced Solid Tumors. Oncologist. 2024 Apr 04; 29(4):e514-e525.
PMID:
38297981
; PMCID:
PMC10994248
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Nelson BE, Roszik J, Ahmed J, Barretto CMN, Nardo M, Campbell E, Johnson AM,
Piha-Paul SA
, Oliva ICG,
Weathers SP
,
Cabanillas M
,
Javle M
,
Meric-Bernstam F
,
Subbiah V
. RAF inhibitor re-challenge therapy in BRAF-aberrant pan-cancers: the RE-RAFFLE study. Mol Cancer. 2024 03 26; 23(1):64.
PMID:
38532456
; PMCID:
PMC10964523
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Heist RS, Sands J, Bardia A, Shimizu T, Lisberg A, Krop I, Yamamoto N, Kogawa T, Al-Hashimi S, Fung SSM, Galor A, Pisetzky F, Basak P, Lau C,
Meric-Bernstam F
. Clinical management, monitoring, and prophylaxis of adverse events of special interest associated with datopotamab deruxtecan. Cancer Treat Rev. 2024 Apr; 125:102720.
PMID:
38502995
.
Citations:
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Subbiah V
, Gouda MA, Iorgulescu JB,
Dadu R
, Patel K,
Sherman S
,
Cabanillas M
,
Hu M
, Castellanos LE,
Amini B
,
Meric-Bernstam F
,
Shen T
, Wu J. Adaptive Darwinian off-target resistance mechanisms to selective RET inhibition in RET driven cancer. NPJ Precis Oncol. 2024 Mar 04; 8(1):62.
PMID:
38438731
; PMCID:
PMC10912412
.
Citations:
1
Goldberg J, Qiao N, Guerriero JL, Gross B, Meneksedag Y, Lu YF, Philips AV, Rahman T,
Meric-Bernstam F
, Roszik J, Chen K, Jeselsohn R, Tolaney SM, Peoples GE, Alatrash G,
Mittendorf EA
. Estrogen Receptor Mutations as Novel Targets for Immunotherapy in Metastatic Estrogen Receptor-positive Breast Cancer. Cancer Res Commun. 2024 02 22; 4(2):496-504.
PMID:
38335301
; PMCID:
PMC10883292
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Subbiah V
, Coleman N,
Piha-Paul SA
,
Tsimberidou AM
,
Janku F
, Rodon J,
Pant S
, Dumbrava EEI,
Fu S
,
Hong DS
, Zhang S, Sun M, Jiang Y, Roszik J, Song J,
Yuan Y
,
Meric-Bernstam F
,
Naing A
. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies. Cancer Res Commun. 2024 02 12; 4(2):378-387.
PMID:
38126764
; PMCID:
PMC10860536
.
Citations:
1
Translation:
Humans
CT
Clinical Trials
Nowlen CJ, Daniels M, Uzunparmak B, Ileana Dumbrava EE, Yuan Y,
Patel KP
, Rayes N, Harkenrider J, Wathoo C, Veazie J, Luna KA, Wang W, Horombe C,
Javle M
, Ahnert JR, Yap TA,
Arun B
,
Lu KH
,
Meric-Bernstam F
. Limited Independent Follow-Up with Germline Testing of Variants Detected in BRCA1 and BRCA2 by Tumor-Only Sequencing. J Immunother Precis Oncol. 2024 Feb; 7(1):7-17.
PMID:
38327755
; PMCID:
PMC10846638
.
Citations:
Coleman N, Stephen B,
Fu S
,
Karp D
,
Subbiah V
, Ahnert JR,
Piha-Paul SA
, Wright J, Fessahaye SN, Ouyang F, Yilmaz B,
Meric-Bernstam F
,
Naing A
. Phase I study of sapanisertib (CB-228/TAK-228/MLN0128) in combination with ziv-aflibercept in patients with advanced solid tumors. Cancer Med. 2024 Feb; 13(3):e6877.
PMID:
38400671
; PMCID:
PMC10891443
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Newhook TE, Tsai S,
Meric-Bernstam F
. Precision Oncology in Hepatopancreatobiliary Cancer Surgery. Surg Oncol Clin N Am. 2024 Apr; 33(2):343-367.
PMID:
38401914
.
Citations:
1
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Higgins T, Kantor O, Harrison B, Giordano J, McGrath M, Burstein HJ, Schnitt SJ, Rahman T, Vora H, Garrido-Castro A, Tolaney SM,
Meric-Bernstam F
, King TA,
Mittendorf EA
. Defining the Biology of Estrogen Receptor-Low-Positive Breast Cancer. Ann Surg Oncol. 2024 Apr; 31(4):2244-2252.
PMID:
38161200
.
Citations:
1
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Wu Y, Chen S, Yang X, Sato K, Lal P, Wang Y, Shinkle AT, Wendl MC, Primeau TM, Zhao Y, Gould A, Sun H, Mudd JL, Hoog J, Mashl RJ, Wyczalkowski MA, Mo CK, Liu R, Herndon JM, Davies SR, Liu D, Ding X, Evrard YA, Welm BE, Lum D, Koh MY, Welm AL, Chuang JH, Moscow JA,
Meric-Bernstam F
, Govindan R, Li S, Hsieh J, Fields RC, Lim KH, Ma CX, Zhang H, Ding L, Chen F. Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma. Cancer Res. 2023 12 15; 83(24):4161-4178.
PMID:
38098449
; PMCID:
PMC10722140
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Harris LN, Blanke CD, Erba HP, Ford JM, Gray RJ, LeBlanc ML, Hu-Lieskovan S, Litzow MR, Luger SM,
Meric-Bernstam F
, O'Dwyer PJ, Othus MKD, Politi K, Shepherd LE, Allegra CJ, Chen HX, Ivy SP, Korde LA, Little RF, McShane LM, Moscow JA, Patton DR, Thurin M, Yee LM, Doroshow JH. The New NCI Precision Medicine Trials. Clin Cancer Res. 2023 12 01; 29(23):4728-4732.
PMID:
37531248
; PMCID:
PMC10690084
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Saridogan T,
Akcakanat A
, Zhao M, Evans KW, Yuca E, Scott S, Kirby BP, Zheng X,
Ha MJ
, Chen H, Ng PKS, DiPeri TP,
Mills GB
, Rodon Ahnert J,
Damodaran S
,
Meric-Bernstam F
. Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer. Sci Rep. 2023 11 18; 13(1):20223.
PMID:
37980453
; PMCID:
PMC10657448
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Animals
Woodfin AA, Yam C,
Teshome M
,
Kuerer HM
,
Hunt KK
,
Meric-Bernstam F
,
Schaverien M
,
Barcenas CH
, Sun SX. Axillary Nodal Metastases Conversion and Perioperative Complications with Neoadjuvant Pembrolizumab Therapy in Triple-Negative Breast Cancer. Ann Surg Oncol. 2024 Feb; 31(2):974-980.
PMID:
37973647
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
DiPeri TP, Zhao M, Evans KW, Varadarajan K, Moss T, Scott S, Kahle MP, Byrnes CC, Chen H, Lee SS, Halim AB, Hirai H, Wacheck V,
Kwong LN
, Rodon J,
Javle M
,
Meric-Bernstam F
. Convergent MAPK pathway alterations mediate acquired?resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinoma. J Hepatol. 2024 02; 80(2):322-334.
PMID:
37972659
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
DiPeri TP, Evans KW, Raso MG,
Zhao M
, Rizvi YQ, Zheng X, Wang B, Kirby BP, Kong K, Kahle M, Yap TA, Dumbrava EE,
Ajani JA
,
Fu S
,
Keyomarsi K
,
Meric-Bernstam F
. Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers. Clin Cancer Res. 2023 11 01; 29(21):4385-4398.
PMID:
37279095
; PMCID:
PMC10618648
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Oaknin A, Oh DY, Jung KH, Manso L, Manzano A, Melichar B, Siena S, Stroyakovskiy D, Lee JY,
Meric-Bernstam F
, Makker V, Banerjee S, Gonz?lez-Mart?n A, Lugowska I, Fielding A, Ma Y, Puvvada S, Shire N. Efficacy and Safety of Trastuzumab Deruxtecan in Patients With HER2-Expressing Solid Tumors: Primary Results From the DESTINY-PanTumor02 Phase II Trial. J Clin Oncol. 2024 Jan 01; 42(1):47-58.
PMID:
37870536
; PMCID:
PMC10730032
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Phadnis S, Wang X, Daw NC, Herzog CE, Subbiah IM, Zaky W, Gouda MA, Morani AC, Amini B, Harrison DJ,
Piha-Paul SA
,
Meric-Bernstam F
, Gorlick R, Schwartz CL, Subbiah V. Everolimus in combination with vandetanib in children, adolescents, and young adults: a phase I study. ESMO Open. 2023 Dec; 8(6):101609.
PMID:
37879233
; PMCID:
PMC10774869
.
Citations:
1
Translation:
Humans
CT
Clinical Trials
Knisely A, Ahmed J, Stephen B,
Piha-Paul SA
,
Karp D
, Zarifa A,
Fu S
,
Hong DS
, Rodon Ahnert J, Yap TA,
Tsimberidou AM
, Alshawa A, Dumbrava EE, Yang Y, Song J,
Meric-Bernstam F
,
Jazaeri AA
,
Naing A
. Phase 1/2 trial of avelumab combined with utomilumab (4-1BB agonist), PF-04518600 (OX40 agonist), or radiotherapy in patients with advanced gynecologic malignancies. Cancer. 2024 02 01; 130(3):400-409.
PMID:
37864520
; PMCID:
PMC10841432
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Tsimberidou AM
, Kahle M, Vo HH, Baysal MA, Johnson A,
Meric-Bernstam F
. Molecular tumour boards - current and future considerations for precision oncology. Nat Rev Clin Oncol. 2023 Dec; 20(12):843-863.
PMID:
37845306
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Sweeney CJ, Hainsworth JD, Bose R, Burris HA, Kurzrock R, Swanton C, Friedman CF, Spigel DR, Szado T, Schulze K, Price R, Malato J, Lo AA, Levy J, Wang Y, Yu W,
Meric-Bernstam F
. MyPathway Human Epidermal Growth Factor Receptor 2 Basket Study: Pertuzumab + Trastuzumab Treatment of a Tissue-Agnostic Cohort of Patients With Human Epidermal Growth Factor Receptor 2-Altered Advanced Solid Tumors. J Clin Oncol. 2024 Jan 20; 42(3):258-265.
PMID:
37793085
; PMCID:
PMC10824375
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Navarro-Yepes J, Kettner NM, Rao X, Bishop CS, Bui TN, Wingate HF, Singareeka Raghavendra A, Wang Y, Wang J,
Sahin AA
,
Meric-Bernstam F
,
Hunt KK
,
Damodaran S
, Tripathy D,
Keyomarsi K
. Abemaciclib Is Effective in Palbociclib-Resistant Hormone Receptor-Positive Metastatic Breast Cancers. Cancer Res. 2023 10 02; 83(19):3264-3283.
PMID:
37384539
; PMCID:
PMC10592446
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Calvo E,
Meric-Bernstam F
, Lee KS, Moreno V, Park YH, Rha SY, Chalasani P, Zhong W, Zhou L, Pirie-Shepherd S, Leung ACF, Curigliano G. Safety and Tolerability of a Novel Anti-HER2 Antibody-Drug Conjugate (PF-06804103) in Patients with HER2-Expressing Solid Tumors: A Phase 1 Dose-Escalation Study. Mol Cancer Ther. 2023 10 02; 22(10):1191-1203.
PMID:
37420274
; PMCID:
PMC10543980
.
Citations:
5
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
CT
Clinical Trials
Nelson BE,
Meric-Bernstam F
. Leveraging TROP2 Antibody-Drug Conjugates in Solid Tumors. Annu Rev Med. 2024 Jan 29; 75:31-48.
PMID:
37758237
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Farley C, Bassett R,
Meric-Bernstam F
,
Bedrosian I
,
Caudle A
,
DeSnyder S
,
Hunt K
,
Kuerer H
, Singh P, Sun S, Tamirisa N,
Teshome M
,
Hwang RF
. To Dissect or Not to Dissect: Can We Predict the Presence of Four or More Axillary Lymph Node Metastases in Postmenopausal Women with Clinically Node-Negative Breast Cancer? Ann Surg Oncol. 2023 Dec; 30(13):8327-8334.
PMID:
37670121
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Rohatgi N, Rothe M, Mangat PK, Garrett-Mayer E,
Meric-Bernstam F
, Pisick E, Alese OB, Reynolds CM, Thota R, Vaccaro GM, von Mehren M, Arend RC, Chiu VK, Duvivier HL, Gold PJ, Hack K, Marr AS, Winer A, Grantham GN, Hinshaw DC, Gregory A, Halabi S, Schilsky RL. Nivolumab Plus Ipilimumab in Patients With Solid Tumors With ATM Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study. JCO Precis Oncol. 2023 Sep; 7:e2300279.
PMID:
38039429
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Meric-Bernstam F
, Rothe M, Mangat PK, Garrett-Mayer E, Gutierrez R, Ahn ER, Cannon TL, Powell S, Krauss JC, Reynolds CM, von Mehren M, Behl D, Calfa CJ, Duvivier HL, Kaplan HG, Livingston MB, Sharma MR, Urba WJ, Grantham GN, Hinshaw DC, Gregory A, Halabi S, Schilsky RL. Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study. JCO Precis Oncol. 2023 Sep; 7:e2300385.
PMID:
38096472
; PMCID:
PMC10735080
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Uzunparmak B, Haymaker C, Raso G, Masciari S, Wang L, Lin H, Gorur A, Kirby B, Cimo AM, Kennon A, Ding Q, Urschel G, Yuan Y, Feng G, Rizvi Y, Hussain A, Zhu C, Kim P, Abbadessa G, Subbiah V, Yap TA, Rodon J,
Piha-Paul SA
,
Meric-Bernstam F
, Dumbrava EE. HER2-low expression in patients with advanced or metastatic solid tumors. Ann Oncol. 2023 11; 34(11):1035-1046.
PMID:
37619847
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Zhao M, DiPeri TP, Raso MG, Zheng X, Rizvi YQ, Evans KW, Yang F,
Akcakanat A
, Roberto Estecio M, Tripathy D, Dumbrava EE,
Damodaran S
,
Meric-Bernstam F
. Epigenetically upregulating TROP2 and SLFN11 enhances therapeutic efficacy of TROP2 antibody drug conjugate sacitizumab govitecan. NPJ Breast Cancer. 2023 Aug 11; 9(1):66.
PMID:
37567892
; PMCID:
PMC10421911
.
Citations:
2
Stephen B,
Hajjar J
, Sarda S, Duose DY, Conroy JM, Morrison C, Alshawa A, Xu M, Zarifa A,
Patel SP
,
Yuan Y
, Kwiatkowski E, Wang L, Rodon Ahnert J,
Fu S
,
Meric-Bernstam F
, Lowman GM, Looney T,
Naing A
. T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy. J Immunother Cancer. 2023 08; 11(8).
PMID:
37604642
; PMCID:
PMC10445351
.
Citations:
3
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
DiPeri TP, Kong K, Varadarajan K,
Karp DD
,
Ajani JA
,
Pant S
, Press MF,
Piha-Paul SA
, Dumbrava EE,
Meric-Bernstam F
. Discordance of HER2 Expression and/or Amplification on Repeat Testing. Mol Cancer Ther. 2023 Aug 01; 22(8):976-984.
PMID:
37339271
; PMCID:
PMC10751575
.
Citations:
2
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Nze C, Msaouel P, Derbala MH, Stephen B, Abonofal A,
Meric-Bernstam F
,
Tannir NM
,
Naing A
. A Phase II Clinical Trial of Pembrolizumab Efficacy and Safety in Advanced Renal Medullary Carcinoma. Cancers (Basel). 2023 Jul 27; 15(15).
PMID:
37568622
; PMCID:
PMC10417298
.
Citations:
1
Gouda MA, Hu MI, Cabanillas ME, Wu J,
Meric-Bernstam F
, Subbiah V. Weight gain in patients with RET aberrant cancers treated with brain penetrant RET selective inhibitors. Ann Oncol. 2023 10; 34(10):946-948.
PMID:
37473872
; PMCID:
PMC11189099
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Johnson A, Ng PK, Kahle M, Castillo J, Amador B, Wang Y, Zeng J, Holla V, Vu T, Su F, Kim SH, Conway T, Jiang X, Chen K, Shaw KRM, Yap TA, Rodon J,
Mills GB
,
Meric-Bernstam F
. Actionability classification of variants of unknown significance correlates with functional effect. NPJ Precis Oncol. 2023 Jul 15; 7(1):67.
PMID:
37454202
; PMCID:
PMC10349825
.
Citations:
Aldea M, Negrao MV, Araujo HA, Lamberti G, Cooper AJ, Akhave NS, Zhou T, Delasos L, Hicks JK, Minuti G, Hines J, Aredo JV, Dennis MJ, Chakrabarti T, Scott SC, Bironzo P, Scheffler M, Christopoulos P, Stenzinger A, Riess JW, Kim SY, Goldberg SB, Li M, Wang Q, Qing Y, Ni Y, Do MT, Lee R, Ricciuti B, Alessi JV, Wang J, Resuli B, Landi L, Tseng SC, Nishino M, Digumarthy SR, Rinsurongkawong W, Rinsurongkawong V,
Vaporciyan AA
,
Blumenschein GR
, Zhang J, Owen DH, Blakely CM, Mountzios G, Shu CA, Bestvina CM, Garassino MC, Marrone KA, Gray JE, Patel SP, Cummings AL, Wakelee HA, Wolf J, Scagliotti GV, Cappuzzo F, Barlesi F, Patil PD, Drusbosky L,
Gibbons DL
,
Meric-Bernstam F
, Lee JJ,
Heymach JV
,
Hong DS
, Heist RS, Awad MM,
Skoulidis F
. Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC. Cancer Discov. 2023 07 07; 13(7):1556-1571.
PMID:
37068173
; PMCID:
PMC11024958
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Chelariu-Raicu A,
Piha-Paul SA
, Chavez-MacGregor M, Johnson J,
Sawaya R
,
McAleer MF
, Nguyen A, Hartnett A,
Tsimberidou AM
,
Meric-Bernstam F
, Dumbrava EE. Multidisciplinary Care of a Large Brain Metastasis in a Patient with Hormone-Receptor-Positive Breast Cancer with Ataxia-Telangiectasia Mutation. J Immunother Precis Oncol. 2023 Aug; 6(3):158-161.
PMID:
37637237
; PMCID:
PMC10448731
.
Citations:
Repetto M, Crimini E, Belli C, Boscolo Bielo L, Ascione L,
Meric-Bernstam F
, Drilon A, Curigliano G. A demand-offer critical analysis of current drug development. Phase I drugs versus TCGA sequencing data. Eur J Cancer. 2023 09; 190:112958.
PMID:
37451181
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Shimizu T, Sands J, Yoh K, Spira A, Garon EB, Kitazono S, Johnson ML,
Meric-Bernstam F
, Tolcher AW, Yamamoto N, Greenberg J, Kawasaki Y, Zebger-Gong H, Kobayashi F, Phillips P, Lisberg AE, Heist RS. First-in-Human, Phase I Dose-Escalation and Dose-Expansion Study of Trophoblast Cell-Surface Antigen 2-Directed Antibody-Drug Conjugate Datopotamab Deruxtecan in Non-Small-Cell Lung Cancer: TROPION-PanTumor01. J Clin Oncol. 2023 10 10; 41(29):4678-4687.
PMID:
37327461
; PMCID:
PMC10564307
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Piha-Paul SA
, Tseng C, Tran HT, Gao M,
Karp DD
,
Subbiah V
,
Tsimberidou AM
, Kawedia JD,
Fu S
,
Pant S
, Yap TA,
Morris VK
,
Kee BK
,
Blum Murphy M
, Lim J,
Meric-Bernstam F
. A phase I trial of the pan-ERBB inhibitor neratinib combined with the MEK inhibitor trametinib in patients with advanced cancer with EGFR mutation/amplification, HER2 mutation/amplification, HER3/4 mutation or KRAS mutation. Cancer Chemother Pharmacol. 2023 08; 92(2):107-118.
PMID:
37314501
; PMCID:
PMC10326142
.
Citations:
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Meric-Bernstam F
, Sweis RF, Hodi FS, Messersmith WA, Andtbacka RHI, Ingham M, Lewis N, Chen X, Pelletier M, Chen X, Wu J, Dubensky TW, McWhirter SM, M?ller T, Nair N, Luke JJ. Correction: Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas. Clin Cancer Res. 2023 06 13; 29(12):2336.
PMID:
37309603
.
Citations:
Fields:
Neo
Neoplasms
Yap TA, Fontana E, Lee EK, Spigel DR, H?jgaard M, Lheureux S, Mettu NB, Carneiro BA, Carter L, Plummer R, Cote GM,
Meric-Bernstam F
, O'Connell J, Schonhoft JD, Wainszelbaum M, Fretland AJ, Manley P, Xu Y, Ulanet D, Rimkunas V, Zinda M, Koehler M, Silverman IM, Reis-Filho JS, Rosen E. Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results. Nat Med. 2023 Jun; 29(6):1400-1411.
PMID:
37277454
; PMCID:
PMC10287555
.
Citations:
9
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
CT
Clinical Trials
Altan M,
Tu J
, Milton DR, Yilmaz B, Tian Y,
Fossella FV
,
Mott FE
,
Blumenschein GR
, Stephen B,
Karp DD
,
Meric-Bernstam F
,
Heymach JV
,
Naing A
. Safety, tolerability, and clinical activity of selinexor in combination with pembrolizumab in treatment of metastatic non-small cell lung cancer. Cancer. 2023 09 01; 129(17):2685-2693.
PMID:
37129197
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Carmagnani Pestana R, Moyers JT, Roszik J, Sen S,
Hong DS
,
Naing A
,
Herzog CE
,
Fu S
,
Piha-Paul SA
, Rodon J, Yap TA,
Karp DD
,
Tsimberidou AM
,
Pant S
,
Zarzour MA
,
Ratan R
,
Ravi V
, Benjamin RS,
Lazar AJ
, Wang WL, Daw N, Gill JB, Harrison DJ,
Lewis VO
,
Roland CL
,
Patel SR
, Livingston JA,
Somaiah N
,
Ludwig JA
,
Conley AP
, Hamerschlak N, Gorlick R,
Meric-Bernstam F
,
Subbiah V
. Impact of Biomarker-Matched Therapies on Outcomes in Patients with Sarcoma Enrolled in Early-Phase Clinical Trials (SAMBA 101). Clin Cancer Res. 2023 05 01; 29(9):1708-1718.
PMID:
37058010
; PMCID:
PMC10150251
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Alhalabi O, Groisberg R, Zinner R, Hahn AW,
Naing A
, Zhang S,
Tsimberidou AM
, Rodon J,
Fu S
, Yap TA,
Hong DS
, Sun M, Jiang Y,
Pant S
,
Shah AY
, Zurita A,
Tannir NM
,
Vikram R
, Roszik J,
Meric-Bernstam F
,
Subbiah V
. Phase I study of sapanisertib with carboplatin and paclitaxel in mTOR pathway altered solid malignancies. NPJ Precis Oncol. 2023 Apr 18; 7(1):37.
PMID:
37072571
; PMCID:
PMC10113233
.
Citations:
Meric-Bernstam F
, Ford JM, O'Dwyer PJ, Shapiro GI, McShane LM, Freidlin B, O'Cearbhaill RE, George S, Glade-Bender J, Lyman GH, Tricoli JV, Patton D,
Hamilton SR
, Gray RJ, Hawkins DS, Ramineni B, Flaherty KT, Grivas P, Yap TA, Berlin J, Doroshow JH, Harris LN, Moscow JA. National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH). Clin Cancer Res. 2023 04 14; 29(8):1412-1422.
PMID:
36662819
; PMCID:
PMC10102840
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Gouda MA, Duose DY, Lapin M, Zalles S, Huang HJ, Xi Y, Zheng X, Aldesoky AI, Alhanafy AM, Shehata MA, Wang J, Kopetz S,
Meric-Bernstam F
,
Wistuba II
,
Luthra R
,
Janku F
. Mutation-Agnostic Detection of Colorectal Cancer Using Liquid Biopsy-Based Methylation-Specific Signatures. Oncologist. 2023 04 06; 28(4):368-372.
PMID:
36200910
; PMCID:
PMC10078907
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Nelson BE,
Saleem S
,
Damodaran S
,
Somaiah N
,
Piha-Paul S
, Moore JA, Yilmaz B, Ogbonna D,
Karp DD
, Dumbrava E,
Tsimberidou AM
,
Hong DS
, Rodon Ahnert J, Milton DR, Zheng X,
Booser DJ
,
Ibrahim NK
,
Conley AP
, Bhosale P,
Rojas Hernandez CM
,
Tripathy D
,
Naing A
,
Meric-Bernstam F
. Phase 1b study of combined selinexor and eribulin for the treatment of advanced solid tumors and triple-negative breast cancer. Cancer. 2023 07 15; 129(14):2201-2213.
PMID:
37016732
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Nelson BE, Roszik J,
Janku F
,
Hong DS
, Kato S,
Naing A
,
Piha-Paul S
,
Fu S
,
Tsimberidou A
,
Cabanillas M
,
Busaidy NL
,
Javle M
,
Byers LA
,
Heymach JV
,
Meric-Bernstam F
,
Subbiah V
. BRAF v600E-mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study. NPJ Precis Oncol. 2023 Feb 18; 7(1):19.
PMID:
36801912
; PMCID:
PMC9938883
.
Citations:
Harding JJ,
Piha-Paul SA
, Shah RH, Murphy JJ, Cleary JM, Shapiro GI, Quinn DI, Bra?a I, Moreno V, Borad M, Loi S, Spanggaard I, Park H, Ford JM, Arnedos M, Stemmer SM, de la Fouchardiere C, Fountzilas C, Zhang J, DiPrimeo D, Savin C, Duygu Selcuklu S, Berger MF, Eli LD,
Meric-Bernstam F
, Jhaveri K, Solit DB, Abou-Alfa GK. Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers. Nat Commun. 2023 02 06; 14(1):630.
PMID:
36746967
; PMCID:
PMC9902444
.
Citations:
2
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Goyal L,
Meric-Bernstam F
, Hollebecque A, Valle JW, Morizane C, Karasic TB, Abrams TA, Furuse J, Kelley RK, Cassier PA, Kl?mpen HJ, Chang HM, Chen LT, Tabernero J, Oh DY, Mahipal A, Moehler M, Mitchell EP, Komatsu Y, Masuda K, Ahn D, Epstein RS, Halim AB, Fu Y, Salimi T, Wacheck V, He Y, Liu M, Benhadji KA, Bridgewater JA, FOENIX-CCA2 Study Investigators. Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma. N Engl J Med. 2023 01 19; 388(3):228-239.
PMID:
36652354
.
Citations:
27
Fields:
Med
Medicine (General)
Yap TA,
Daver N
, Mahendra M, Zhang J, Kamiya-Matsuoka C,
Meric-Bernstam F
,
Kantarjian HM
, Ravandi F, Collins ME, Francesco MED, Dumbrava EE,
Fu S
, Gao S, Gay JP, Gera S, Han J,
Hong DS
,
Jabbour EJ
, Ju Z,
Karp DD
, Lodi A, Molina JR, Baran N,
Naing A
,
Ohanian M
,
Pant S
,
Pemmaraju N
,
Bose P
,
Piha-Paul SA
, Rodon J, Salguero C, Sasaki K, Singh AK,
Subbiah V
,
Tsimberidou AM
, Xu QA, Yilmaz M, Zhang Q, Li Y, Bristow CA, Bhattacharjee MB, Tiziani S, Heffernan TP, Vellano CP, Jones P,
Heijnen CJ
,
Kavelaars A
, Marszalek JR,
Konopleva M
. Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nat Med. 2023 01; 29(1):115-126.
PMID:
36658425
.
Citations:
28
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
CT
Clinical Trials
Hunt KK
, Suman VJ, Wingate HF, Leitch AM, Unzeitig G, Boughey JC,
Meric-Bernstam F
, Ellis MJ, Olson J. Local-Regional Recurrence After Neoadjuvant Endocrine Therapy: Data from ACOSOG Z1031 (Alliance), a Randomized Phase 2 Neoadjuvant Comparison Between Letrozole, Anastrozole, and Exemestane for Postmenopausal Women with Estrogen Receptor-Positive Clinical Stage 2 or 3 Breast Cancer. Ann Surg Oncol. 2023 Apr; 30(4):2111-2118.
PMID:
36653664
; PMCID:
PMC10373661
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Moyers JT, Pestana RC, Roszik J,
Hong DS
,
Naing A
,
Fu S
,
Piha-Paul S
, Yap TA,
Karp D
, Rodon J, Livingston A,
Zarzour MA
,
Ravi V
,
Patel S
, Benjamin RS,
Ludwig J
,
Herzog C
,
Ratan R
,
Somaiah N
,
Conley A
, Gorlick R,
Meric-Bernstam F
,
Subbiah V
. Examining Stripes on a Herd of Zebras: Impact of Genomic Matching for Ultrarare Sarcomas in Phase 1 Clinical Trials (SAMBA 102). Clin Cancer Res. 2023 01 17; 29(2):401-409.
PMID:
36288393
; PMCID:
PMC9843435
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Coleman N, Yap TA,
Heymach JV
,
Meric-Bernstam F
, Le X. Antibody-drug conjugates in lung cancer: dawn of a new era? NPJ Precis Oncol. 2023 Jan 11; 7(1):5.
PMID:
36631624
; PMCID:
PMC9834242
.
Citations:
9
Son J, Lin HY,
Fu S
, Biter AB, Dumbrava EE,
Karp DD
,
Naing A
,
Pant S
,
Piha-Paul SA
, Rodon J,
Subbiah V
,
Tsimberidou AM
, Yap TA,
Frumovitz MM
,
Jazaeri AA
,
Ramirez PT
,
Westin SN
,
Yuan Y
,
Meric-Bernstam F
,
Hong DS
. Predictors of Oncologic Outcome in Patients Receiving Phase I Investigational Therapy for Recurrent or Metastatic Cervical Cancer. J Immunother Precis Oncol. 2023 Feb; 6(1):10-18.
PMID:
36751659
; PMCID:
PMC9888522
.
Citations:
Meric-Bernstam F
, Sweis RF, Kasper S, Hamid O, Bhatia S, Dummer R, Stradella A, Long GV, Spreafico A, Shimizu T, Steeghs N, Luke JJ, McWhirter SM, M?ller T, Nair N, Lewis N, Chen X, Bean A, Kattenhorn L, Pelletier M, Sandhu S. Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study. Clin Cancer Res. 2023 01 04; 29(1):110-121.
PMID:
36282874
; PMCID:
PMC11188043
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Fu S
, Yao S, Yuan Y, Previs RA, Elias AD, Carvajal RD, George TJ,
Yuan Y
, Yu L,
Westin SN
, Xing Y, Dumbrava EE,
Karp DD
,
Piha-Paul SA
,
Tsimberidou AM
, Ahnert JR, Takebe N,
Lu K
,
Keyomarsi K
,
Meric-Bernstam F
. Multicenter Phase II Trial of the WEE1 Inhibitor Adavosertib in Refractory Solid Tumors Harboring CCNE1 Amplification. J Clin Oncol. 2023 03 20; 41(9):1725-1734.
PMID:
36469840
; PMCID:
PMC10489509
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Westin SN
,
Fu S
,
Tsimberidou A
,
Piha-Paul S
, Akhmedzhanov F, Yilmaz B, McQuinn L, Brink AL, Gong J, Leung CH, Lin H,
Hong DS
,
Pant S
,
Carter B
,
Jazaeri A
, Gershenson D,
Sood AK
,
Coleman RL
, Shah J,
Meric-Bernstam F
,
Naing A
. Selinexor in combination with weekly paclitaxel in patients with metastatic solid tumors: Results of an open label, single-center, multi-arm phase 1b study with expansion phase in ovarian cancer. Gynecol Oncol. 2023 01; 168:76-82.
PMID:
36423446
; PMCID:
PMC9797438
.
Citations:
1
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Meric-Bernstam F
, Beeram M, Hamilton E, Oh DY, Hanna DL, Kang YK, Elimova E, Chaves J, Goodwin R, Lee J, Nabell L, Rha SY, Mayordomo J, El-Khoueiry A,
Pant S
,
Raghav K
, Kim JW, Patnaik A, Gray T, Davies R, Ozog MA, Woolery J, Lee KW. Zanidatamab, a novel bispecific antibody, for the treatment of locally advanced or metastatic HER2-expressing or HER2-amplified cancers: a phase 1, dose-escalation and expansion study. Lancet Oncol. 2022 12; 23(12):1558-1570.
PMID:
36400106
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Leighton J, Hu M, Sei E,
Meric-Bernstam F
,
Navin NE
. Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing. Cell Genom. 2023 Jan 11; 3(1):100215.
PMID:
36777188
; PMCID:
PMC9903705
.
Citations:
2
Qing T, Karn T, Rozenblit M, Foldi J, Marczyk M, Shan NL, Blenman K, Holtrich U, Kalinsky K,
Meric-Bernstam F
, Pusztai L. Molecular differences between younger versus older ER-positive and HER2-negative breast cancers. NPJ Breast Cancer. 2022 Nov 07; 8(1):119.
PMID:
36344517
; PMCID:
PMC9640562
.
Citations:
2
Alhalabi O, Altameemi L, Campbell MT,
Meric-Bernstam F
. Recent Advances in the Development of Antibody-Drug Conjugates in Urothelial Cancer. Cancer J. 2022 Nov-Dec 01; 28(6):417-422.
PMID:
36383903
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Vo HH, Fu S,
Hong DS
,
Karp DD
,
Piha-Paul S
,
Subbiah V
,
Janku F
,
Naing A
, Yap TA, Rodon J,
Ajani JA
, Cartwright C, Johnson A, Song IW, Beck J, Kahle M, Nogueras-Gonzalez GM, Miller V, Chao C,
Vining DJ
,
Berry DA
,
Meric-Bernstam F
,
Tsimberidou AM
. Challenges and opportunities associated with the MD Anderson IMPACT2 randomized study in precision oncology. NPJ Precis Oncol. 2022 Oct 27; 6(1):78.
PMID:
36302890
; PMCID:
PMC9612600
.
Citations:
1
Barroso M, Chheda MG, Clevers H, Elez E, Kaochar S, Kopetz SE, Li XN,
Meric-Bernstam F
, Meyer CA, Mou H, Naegle KM, Pera MF, Perova Z, Politi KA, Raphael BJ, Robson P, Sears RC, Tabernero J, Tuveson DA, Welm AL, Welm BE, Willey CD, Salnikow K, Chuang JH, Shen X, Bose S. A path to translation: How 3D patient tumor avatars enable next generation precision oncology. Cancer Cell. 2022 12 12; 40(12):1448-1453.
PMID:
36270276
; PMCID:
PMC10576652
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Barber FD, Campbell E, Yamamura Y, Patterson CJ, Hartnett AC, Kinahan H, Miller VA, Brink AL, Poullard A, Urschel GE, Brantley A, Cepeda IG, Goswami P, Charles S, Philip S, Bresser S, Musekiwa-Adjei S,
Perez N
, Le H, Phillips P,
Subbiah V
,
Meric-Bernstam F
, Dumbrava EE. Management of Adverse Events in Early Clinical Trials by Advanced Practice Providers in the Outpatient Setting: The University of Texas MD Anderson Cancer Center Experience. J Adv Pract Oncol. 2022 Sep; 13(7):664-672.
PMID:
36199491
; PMCID:
PMC9514129
.
Citations:
1
Davis JS, Chavez JC, Kok M, San Miguel Y, Lee HY, Henderson H,
Overman MJ
,
Morris V
,
Kee B
,
Fogelman D
, Advani SM, Johnson B, Parseghian C, Shen JP, Dasari A, Shaw KR, Vilar E,
Raghav KP
,
Shureiqi I
,
Wolff RA
,
Meric-Bernstam F
,
Maru D
,
Menter DG
, Kopetz S,
Chang S
. Association of Prediagnosis Obesity and Postdiagnosis Aspirin With Survival From Stage IV Colorectal Cancer. JAMA Netw Open. 2022 10 03; 5(10):e2236357.
PMID:
36239938
; PMCID:
PMC9568800
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Gupta R,
Meric-Bernstam F
, Rothe M, Garrett-Mayer E, Mangat PK, D'Andre S, Ahn ER, O'Lone R, Halabi S, Grantham GN, Schilsky RL. Pertuzumab Plus Trastuzumab in Patients With Colorectal Cancer With ERBB2 Amplification or ERBB2/3 Mutations: Results From the TAPUR Study. JCO Precis Oncol. 2022 Oct; 6:e2200306.
PMID:
36315917
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Mendoza TR
,
Hong DS
, Peterson CB, Stephen B, Dumbrava E, Pant S,
Tsimberidou AM
, Yap TA,
Sheshadri A
, Altan M,
George G
, Castillo L, Rodriguez E, Gong J,
Subbiah V
,
Janku F
,
Fu S
,
Piha-Paul SA
, Ahnert JR,
Karp DD
,
Cleeland C
,
Meric-Bernstam F
,
Naing A
. Patient-reported symptom burden in patients with rare cancers receiving pembrolizumab in a phase II Clinical Trial. Sci Rep. 2022 08 23; 12(1):14367.
PMID:
35999229
; PMCID:
PMC9399082
.
Citations:
How JA,
Jazaeri AA
,
Fu S
, Rodon Ahnert J, Gong J, Stephen B, Ferreira Dalla Pria H, Bhosale P, Johnson A,
Yuan Y
,
Meric-Bernstam F
,
Naing A
. Clinical Outcomes of Patients with Recurrent Microsatellite-Stable Endometrial Cancer in Early-Phase Immunotherapy Clinical Trials. Cancers (Basel). 2022 Jul 29; 14(15).
PMID:
35954359
; PMCID:
PMC9367373
.
Citations:
Huang L, Wang J,
Fang B
,
Meric-Bernstam F
,
Roth JA
,
Ha MJ
. CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts. Sci Rep. 2022 07 29; 12(1):12984.
PMID:
35906256
; PMCID:
PMC9338066
.
Citations:
Fields:
Sci
Science
Gouda MA, Huang HJ,
Piha-Paul SA
, Call SG,
Karp DD
,
Fu S
,
Naing A
,
Subbiah V
,
Pant S
, Dustin DJ,
Tsimberidou AM
,
Hong DS
, Rodon J,
Meric-Bernstam F
,
Janku F
. Longitudinal Monitoring of Circulating Tumor DNA to Predict Treatment Outcomes in Advanced Cancers. JCO Precis Oncol. 2022 07; 6:e2100512.
PMID:
35834760
; PMCID:
PMC9307306
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Thein KZ, Biter AB, Banks KC, Duda AW, Saam J, Roszik J,
Janku F
,
Skoulidis F
,
Heymach JV
, Kopetz S,
Meric-Bernstam F
,
Hong DS
. Identification of KRASG12C Mutations in Circulating Tumor DNA in Patients With Cancer. JCO Precis Oncol. 2022 07; 6:e2100547.
PMID:
35862868
; PMCID:
PMC9365336
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Yao S,
Meric-Bernstam F
,
Hong D
,
Janku F
,
Naing A
,
Piha-Paul SA
,
Tsimberidou AM
,
Karp D
,
Subbiah V
, Yap TA, Ahnert JR,
Pant S
, Dumbrava EEI, Wathoo C, Campbell E, Yu L, Yamamura Y,
Fu S
. Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences. Sci Rep. 2022 05 24; 12(1):8701.
PMID:
35610322
; PMCID:
PMC9130298
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Fidler MJ, Arkenau HT, Spira A,
Meric-Bernstam F
, Uboha N, Sanborn RE, Sweis RF, LoRusso P, Nagasaka M, Garcia-Corbacho J, Jalal S, Harding JJ, Kim SK, Miedema IHC, Vugts DJ, Huisman MC, Zwezerijnen GJC, van Dongen GAMS, Menke van der Houven van Oordt CW, Wang S, Dang T, Zein IA, Vasiljeva O, Lyman SK, Paton V, Hannah A, Liu JF, Boni V. Praluzatamab Ravtansine, a CD166-Targeting Antibody-Drug Conjugate, in Patients with Advanced Solid Tumors: An Open-Label Phase I/II Trial. Clin Cancer Res. 2022 05 13; 28(10):2020-2029.
PMID:
35165101
; PMCID:
PMC9365353
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
LeNoue-Newton ML, Chen SC, Stricker T, Hyman DM, Blauvelt N, Bedard PL,
Meric-Bernstam F
, Punglia RS, Schrag D, Lepisto EM, Andre F, Smyth L, Dogan S, Yu C, Wathoo C, Levy M, Eli LD, Xu F, Mann G, Lalani AS, Ye F, Micheel CM, Arnedos M. Natural History and Characteristics of ERBB2-mutated Hormone Receptor-positive Metastatic Breast Cancer: A Multi-institutional Retrospective Case-control Study from AACR Project GENIE. Clin Cancer Res. 2022 05 13; 28(10):2118-2130.
PMID:
35190802
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Yap TA, Ashok A, Stoll J, Mauer E, Nepomuceno VM, Blackwell KL, Garber JE,
Meric-Bernstam F
. Prevalence of Germline Findings Among Tumors From Cancer Types Lacking Hereditary Testing Guidelines. JAMA Netw Open. 2022 05 02; 5(5):e2213070.
PMID:
35594047
; PMCID:
PMC9123503
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Raghav KP
, Stephen B,
Karp DD
,
Piha-Paul SA
,
Hong DS
, Jain D, Chudy Onwugaje DO, Abonofal A, Willett AF,
Overman M
, Smaglo B, Huey RW,
Meric-Bernstam F
,
Varadhachary GR
,
Naing A
. Efficacy of pembrolizumab in patients with advanced cancer of unknown primary (CUP): a phase 2 non-randomized clinical trial. J Immunother Cancer. 2022 05; 10(5).
PMID:
35618285
; PMCID:
PMC9125753
.
Citations:
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Koc S, Lloyd MW, Grover JW, Xiao N, Seepo S, Subramanian SL, Ray M, Frech C, DiGiovanna J, Webster P, Neuhauser S, Srivastava A, Woo XY, Sanderson BJ, White B, Lott P, Dobrolecki LE, Dowst H, PDXNet Consortium , Evrard YA, Wallace TA, Moscow JA, Doroshow JH, Mitsiades N, Kaochar S, Pan CX, Chen MS, Carvajal-Carmona L, Welm AL, Welm BE,
Lewis MT
, Govindan R, Ding L, Li S, Herlyn M, Davies MA,
Roth J
,
Meric-Bernstam F
, Robinson PN, Bult CJ, Davis-Dusenbery B, Dean DA, Chuang JH. PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery. NAR Cancer. 2022 Jun; 4(2):zcac014.
PMID:
35475145
; PMCID:
PMC9026194
.
Citations:
Le X, Gleber-Netto FO, Rubin ML, Qing Y, Du R,
Kies M
,
Blumenschein G
,
Lu C
,
Johnson FM
,
Bell D
, Lewis J, Zhang J, Feng L, Wilson K, Marcelo-Lewis K,
Ginsberg L
, Gillison M, Lee JJ,
Meric-Bernstam F
,
Mills GB
, William WN,
Myers JN
,
Pickering CR
, Wang J. Induction chemotherapy with or without erlotinib in patients with head and neck squamous cell carcinoma amenable for surgical resection. Clin Cancer Res. 2022 Apr 20.
PMID:
35443062
.
Citations:
Fields:
Neo
Neoplasms
Meric-Bernstam F
,
Tannir NM
, Iliopoulos O, Lee RJ, Telli ML, Fan AC, DeMichele A, Haas NB, Patel MR, Harding JJ, Voss MH, Owonikoko TK, Carthon B, Srinivasan R, Bendell JC, Jenkins Y, Whiting SH, Orford K, Bennett MK, Bauer TM. Telaglenastat Plus Cabozantinib or Everolimus for Advanced or Metastatic Renal Cell Carcinoma: An Open-Label Phase I Trial. Clin Cancer Res. 2022 04 14; 28(8):1540-1548.
PMID:
35140121
; PMCID:
PMC9164172
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Thein KZ,
Karp DD
,
Tsimberidou A
, Gong J, Sulovic S, Shah J,
Hong DS
,
Janku F
, McQuinn L, Stephen BA,
Colen R
,
Carter BW
, Yap TA,
Piha-Paul SA
,
Fu S
,
Meric-Bernstam F
,
Naing A
, Milton DR. Correction to: Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: results of a single-center, multi-arm phase Ib study. Invest New Drugs. 2022 Apr; 40(2):463.
PMID:
34731355
; PMCID:
PMC8993707
.
Citations:
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Thein KZ,
Piha-Paul SA
,
Tsimberidou A
,
Karp DD
,
Janku F
, Zarifa A, Shah J, Bean S, McQuinn L, Gong J,
Colen R
,
Carter BW
,
Subbiah V
, Ogbonna DC,
Pant S
,
Meric-Bernstam F
,
Naing A
, Milton DR. Correction to: Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study. Invest New Drugs. 2022 Apr; 40(2):461.
PMID:
34705134
; PMCID:
PMC8993725
.
Citations:
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Stover EH, Xiong N, Myers AP,
Tayob N
, Engvold V, Polak M,
Broaddus RR
, Makker V, Drapkin R, Liu JF, Horowitz NS,
Meric-Bernstam F
, Aghajanian C,
Coleman RL
,
Mills GB
, Cantley LC, Matulonis UA,
Westin SN
, Konstantinopoulos PA. A phase II study of MK-2206, an AKT inhibitor, in uterine serous carcinoma. Gynecol Oncol Rep. 2022 Apr; 40:100974.
PMID:
35434236
; PMCID:
PMC9011027
.
Citations:
Friedman CF, Hainsworth JD, Kurzrock R, Spigel DR, Burris HA, Sweeney CJ,
Meric-Bernstam F
, Wang Y, Levy J, Grindheim J, Shames DS, Schulze K, Patel A, Swanton C. Atezolizumab Treatment of Tumors with High Tumor Mutational Burden from MyPathway, a Multicenter, Open-Label, Phase IIa Multiple Basket Study. Cancer Discov. 2022 03 01; 12(3):654-669.
PMID:
34876409
; PMCID:
PMC9394388
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Chakravarty D, Johnson A, Sklar J, Lindeman NI, Moore K, Ganesan S, Lovly CM, Perlmutter J, Gray SW, Hwang J, Lieu C, Azad N, Borad M, Tafe L, Messersmith H, Robson M,
Meric-Bernstam F
, Andr? F. Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion. J Clin Oncol. 2022 04 10; 40(11):1231-1258.
PMID:
35175857
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Meric-Bernstam F
, Sweis RF, Hodi FS, Messersmith WA, Andtbacka RHI, Ingham M, Lewis N, Chen X, Pelletier M, Chen X, Wu J, McWhirter SM, Nair N, Luke JJ, M?ller T. Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas. Clin Cancer Res. 2022 02 15; 28(4):677-688.
PMID:
34716197
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Li J, Lu H, Ng PK, Pantazi A, Ip CKM, Jeong KJ, Amador B, Tran R, Tsang YH, Yang L, Song X, Dogruluk T, Ren X, Hadjipanayis A, Bristow CA, Lee S, Kucherlapati M, Parfenov M, Tang J, Seth S, Mahadeshwar HS, Mojumdar K, Zeng D, Zhang J, Protopopov A, Seidman JG,
Creighton CJ
,
Lu Y
,
Sahni N
, Shaw KR,
Meric-Bernstam F
,
Futreal A
, Chin L, Scott KL, Kucherlapati R,
Mills GB
,
Liang H
. A functional genomic approach to actionable gene fusions for precision oncology. Sci Adv. 2022 02 11; 8(6):eabm2382.
PMID:
35138907
; PMCID:
PMC8827659
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Thein KZ,
Fu S
,
Janku F
,
Tsimberidou AM
,
Piha-Paul SA
,
Karp DD
, Shah J, Gong J, Sulovic S, McQuinn L, Stephen BA,
Colen RR
,
Carter BW
,
Meric-Bernstam F
,
Naing A
, Milton DR. Selinexor in Combination with Carboplatin and Pemetrexed in Patients with Advanced or Metastatic Solid Tumors: Results of an Open-Label, Single-Center, Multi-Arm Phase 1b Study. J Immunother Precis Oncol. 2022 Feb; 5(1):10-12.
PMID:
35663832
; PMCID:
PMC9138422
.
Citations:
Zhang X, Zhang R, Ren C, Xu Y, Wu S, Meng C,
Pataer A
, Song X, Zhang J, Yao Y, He H, Chen H, Ma W, Wang J,
Meric-Bernstam F
,
Champlin RE
,
Heymach JV
,
Rooney CM
, Swisher SG,
Vaporciyan AA
,
Roth JA
, You MJ, Wang M, Fang B. Epstein Barr virus-positive B-cell lymphoma is highly vulnerable to MDM2 inhibitors in vivo. Blood Adv. 2022 02 08; 6(3):891-901.
PMID:
34861697
; PMCID:
PMC8945299
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
DiPeri TP, Demirhan M,
Karp DD
,
Fu S
,
Hong DS
,
Subbiah V
, Lim J, Ballester LY,
Tayar JH
,
Suarez-Almazor ME
,
Javle M
,
Meric-Bernstam F
. Corticosteroid-Refractory Myositis After Dual BRAF and MEK Inhibition in a Patient with BRAF V600E-Mutant Metastatic Intrahepatic Cholangiocarcinoma. J Immunother Precis Oncol. 2022 Feb; 5(1):26-30.
PMID:
35663835
; PMCID:
PMC9138421
.
Citations:
Lapin M, Huang HJ, Chagani S,
Javle M
,
Shroff RT
,
Pant S
, Gouda MA, Raina A, Madwani K, Holley VR, Call SG, Dustin DJ, Lanman RB,
Meric-Bernstam F
, Raymond VM,
Kwong LN
,
Janku F
. Monitoring of Dynamic Changes and Clonal Evolution in Circulating Tumor DNA From Patients With IDH-Mutated Cholangiocarcinoma Treated With Isocitrate Dehydrogenase Inhibitors. JCO Precis Oncol. 2022 02; 6:e2100197.
PMID:
35171660
; PMCID:
PMC8865526
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Garmezy B, Gheeya J, Lin HY, Huang Y, Kim T, Jiang X, Thein KZ, Zeineddine F, Wang W, Shaw KR, Rodon J, Shen JP,
Yuan Y
,
Meric-Bernstam F
, Chen K, Yap TA, Pili? PG. Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers. JCO Precis Oncol. 2022 02; 6:e2100267.
PMID:
35108036
; PMCID:
PMC8820927
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Pairawan S,
Akcakanat A
, Kopetz S,
Tapia C
, Zheng X, Chen H,
Ha MJ
, Rizvi Y, Holla V, Wang J, Evans KW,
Zhao M
,
Busaidy N
,
Fang B
,
Roth JA
, Dumbrava EI,
Meric-Bernstam F
. Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations. Sci Rep. 2022 01 24; 12(1):1248.
PMID:
35075200
; PMCID:
PMC8786858
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Saleh MN, Patel MR, Bauer TM, Goel S, Falchook GS, Shapiro GI, Chung KY, Infante JR, Conry RM, Rabinowits G,
Hong DS
, Wang JS, Steidl U, Walensky LD, Naik G, Guerlavais V, Vukovic V, Annis DA, Aivado M,
Meric-Bernstam F
. Correction: Phase I Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53. Clin Cancer Res. 2022 Jan 15; 28(2):429.
PMID:
35045962
; PMCID:
PMC10361214
.
Citations:
Fields:
Neo
Neoplasms
Sun H, Cao S, Mashl RJ, Mo CK, Zaccaria S, Wendl MC, Davies SR, Bailey MH, Primeau TM, Hoog J, Mudd JL, Dean DA, Patidar R, Chen L, Wyczalkowski MA, Jayasinghe RG, Rodrigues FM, Terekhanova NV, Li Y, Lim KH, Wang-Gillam A, Van Tine BA, Ma CX, Aft R, Fuh KC, Schwarz JK, Zevallos JP, Puram SV, Dipersio JF, NCI PDXNet Consortium, Davis-Dusenbery B, Ellis MJ,
Lewis MT
, Davies MA, Herlyn M, Fang B,
Roth JA
, Welm AL, Welm BE,
Meric-Bernstam F
, Chen F, Fields RC, Li S, Govindan R, Doroshow JH, Moscow JA, Evrard YA, Chuang JH, Raphael BJ, Ding L. Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment. Nat Commun. 2022 Jan 07; 13(1):294.
PMID:
34996889
; PMCID:
PMC8742097
.
Citations:
Fields:
Bio
Biology
Sci
Science
Zeng J, Cruz-Pico CX, Shufean MA, Kahle M, Yang D, Shaw K,
Meric-Bernstam F
, Saridogan T. Natural Language Processing-Assisted Literature Retrieval and Analysis for Combination Therapy in Cancer. JCO Clin Cancer Inform. 2022 01; 6:e2100109.
PMID:
34990212
; PMCID:
PMC9848576
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Thein KZ,
Piha-Paul SA
,
Tsimberidou A
,
Karp DD
,
Janku F
,
Fu S
,
Subbiah V
,
Hong DS
, Yap TA, Shah J, McQuinn L, Gong J, Tran Y,
Carter BW
,
Colen R
,
Meric-Bernstam F
,
Naing A
, Milton DR. Selinexor in combination with standard chemotherapy in patients with advanced or metastatic solid tumors. Exp Hematol Oncol. 2021 Dec 29; 10(1):59.
PMID:
34965890
; PMCID:
PMC8715578
.
Citations:
Gouda MA, Polivka J, Huang HJ, Treskova I, Pivovarcikova K, Fikrle T, Woznica V, Dustin DJ, Call SG,
Meric-Bernstam F
, Pesta M,
Janku F
. Ultrasensitive detection of BRAF mutations in circulating tumor DNA of non-metastatic melanoma. ESMO Open. 2022 02; 7(1):100357.
PMID:
34942440
; PMCID:
PMC8695283
.
Citations:
Translation:
Humans
Carapeto F, Bozorgui B,
Shroff RT
, Chagani S, Solis Soto L,
Foo WC
,
Wistuba I
,
Meric-Bernstam F
, Shalaby A,
Javle M
,
Korkut A
,
Kwong LN
. The immunogenomic landscape of resected intrahepatic cholangiocarcinoma. Hepatology. 2022 02; 75(2):297-308.
PMID:
34510503
; PMCID:
PMC8766948
.
Citations:
3
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Coleman N,
Subbiah V
,
Pant S
, Patel K, Roy-Chowdhuri S,
Yedururi S
, Johnson A, Yap TA, Rodon J, Shaw K,
Meric-Bernstam F
. Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition. NPJ Precis Oncol. 2021 Dec 01; 5(1):99.
PMID:
34853384
; PMCID:
PMC8636467
.
Citations:
Kalinsky K, Barlow WE, Gralow JR,
Meric-Bernstam F
, Albain KS, Hayes DF, Lin NU, Perez EA, Goldstein LJ, Chia SKL, Dhesy-Thind S, Rastogi P, Alba E, Delaloge S, Martin M, Kelly CM, Ruiz-Borrego M, Gil-Gil M, Arce-Salinas CH, Brain EGC, Lee ES, Pierga JY, Bermejo B, Ramos-Vazquez M, Jung KH, Ferrero JM, Schott AF, Shak S, Sharma P, Lew DL, Miao J,
Tripathy D
, Pusztai L, Hortobagyi GN. 21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer. N Engl J Med. 2021 12 16; 385(25):2336-2347.
PMID:
34914339
; PMCID:
PMC9096864
.
Citations:
33
Fields:
Med
Medicine (General)
Translation:
Humans
Yao S,
Janku F
,
Koenig K
,
Tsimberidou AM
,
Piha-Paul SA
, Shi N, Stewart J, Johnston A, Bomalaski J,
Meric-Bernstam F
,
Fu S
. Phase 1 trial of ADI-PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors. Cancer Med. 2022 01; 11(2):340-347.
PMID:
34841717
; PMCID:
PMC8729058
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Alhalabi O, Zhu Y, Hamza A, Qiao W, Lin Y, Wang RM,
Shah AY
, Campbell MT, Holla V,
Kamat A
, Wang WL, Wang J, Chen J, Meng J,
Zhang M
, Bondaruk J, Titus M,
Genovese G
,
Czerniak BA
, Shaw KR,
Meric-Bernstam F
,
Guo CC
,
Logothetis CJ
,
Siefker-Radtke A
, Msaouel P, Wang L, Liu J,
Gao J
. Integrative Clinical and Genomic Characterization of MTAP-deficient Metastatic Urothelial Cancer. Eur Urol Oncol. 2023 04; 6(2):228-232.
PMID:
34789422
; PMCID:
PMC9106763
.
Citations:
4
Fields:
Neo
Neoplasms
Uro
Urology
Bernstam EV
, Shireman PK,
Meric-Bernstam F
, N Zozus M, Jiang X, Brimhall BB, Windham AK, Schmidt S, Visweswaran S, Ye Y, Goodrum H, Ling Y, Barapatre S, Becich MJ. Artificial intelligence in clinical and translational science: Successes, challenges and opportunities. Clin Transl Sci. 2022 02; 15(2):309-321.
PMID:
34706145
; PMCID:
PMC8841416
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Sousa LG, Wang K, Torman D, Binks BJ, Rubin ML, Andersen CR, Lewis WE, Rivera MJ, Kaya D,
El-Naggar AK
,
Hanna EY
,
Esmaeli B
,
Frank SJ
,
Bell D
,
Glisson BS
, Rodon J,
Meric-Bernstam F
, Lee JJ,
Ferrarotto R
. Treatment patterns and outcomes of palliative systemic therapy in patients with salivary duct carcinoma and adenocarcinoma, not otherwise specified. Cancer. 2022 02 01; 128(3):509-518.
PMID:
34661906
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Saleh MN, Patel MR, Bauer TM, Goel S, Falchook GS, Shapiro GI, Chung KY, Infante JR, Conry RM, Rabinowits G,
Hong DS
, Wang JS, Steidl U, Naik G, Guerlavais V, Vukovic V, Annis DA, Aivado M,
Meric-Bernstam F
. Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53. Clin Cancer Res. 2021 10 01; 27(19):5236-5247.
PMID:
34301750
; PMCID:
PMC9401461
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
CT
Clinical Trials
Bagheri-Yarmand R,
Busaidy NL
, McBeath E, Danysh BP, Evans KW, Moss TJ,
Akcakanat A
, Ng PKS, Knippler CM, Golden JA,
Williams MD
,
Multani AS
,
Cabanillas ME
, Shaw KR,
Meric-Bernstam F
, Shah MH, Ringel MD,
Hofmann MC
. RAC1 Alterations Induce Acquired Dabrafenib Resistance in Association with Anaplastic Transformation in a Papillary Thyroid Cancer Patient. Cancers (Basel). 2021 Sep 30; 13(19).
PMID:
34638434
; PMCID:
PMC8507731
.
Citations:
1
Thein KZ,
Karp DD
,
Tsimberidou A
, Gong J, Sulovic S, Shah J,
Hong DS
,
Janku F
, McQuinn L, Stephen BA,
Colen R
,
Carter BW
, Yap TA,
Piha-Paul SA
,
Fu S
,
Meric-Bernstam F
,
Naing A
, Milton DR. Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: Results of a single-center, multi-arm phase Ib study. Invest New Drugs. 2022 04; 40(2):290-299.
PMID:
34562230
; PMCID:
PMC8993773
.
Citations:
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Dev R
, Zhong LL, Zarifa A,
Albittar AA
, Rubin L, Liu S, Yap TA,
Dalal S
,
Hui D
,
Karp DD
,
Tsimberidou AM
,
Piha-Paul SA
, Ahnert JR,
Fu S
,
Meric-Bernstam F
,
Naing A
. Supportive care for the prevention of nausea, vomiting and anorexia in a phase 1B study of selinexor in advanced cancer patients: an exploratory study. Invest New Drugs. 2022 02; 40(1):124-133.
PMID:
34559346
.
Citations:
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Moore KN,
Hong DS
, Patel MR,
Pant S
, Ulahannan SV, Jones S,
Meric-Bernstam F
, Wang JS, Aljumaily R, Hamilton EP, Wittchen ES, Wang X, Lin AB, Bendell JC. A Phase 1b Trial of Prexasertib in Combination with Standard-of-Care Agents in Advanced or Metastatic Cancer. Target Oncol. 2021 09; 16(5):569-589.
PMID:
34559360
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Meric-Bernstam F
, Bahleda R, Hierro C, Bridgewater J, Arkenau HT, Tran B, Kelley RK, Park JO,
Javle M
, He Y, Benhadji KA, Goyal L, Sanson M. Futibatinib, an Irreversible FGFR1-4 Inhibitor, in Patients with Advanced Solid Tumors Harboring FGF/FGFR Aberrations: A Phase I Dose-Expansion Study. Cancer Discov. 2022 02; 12(2):402-415.
PMID:
34551969
; PMCID:
PMC9762334
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Evans KW, Yuca E, Scott SS,
Zhao M
, Paez Arango N, Cruz Pico CX, Saridogan T, Shariati M, Class CA, Bristow CA, Vellano CP, Zheng X, Gonzalez-Angulo AM,
Su X
,
Tapia C
, Chen K,
Akcakanat A
, Lim B, Tripathy D, Yap TA, Francesco MED,
Draetta GF
, Jones P, Heffernan TP, Marszalek JR,
Meric-Bernstam F
. Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer. Cancer Res. 2021 11 01; 81(21):5572-5581.
PMID:
34518211
; PMCID:
PMC8563442
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Dumbrava EE, Call SG, Huang HJ, Stuckett AL, Madwani K, Adat A, Hong DS,
Piha-Paul SA
, Subbiah V,
Karp DD
, Fu S, Naing A,
Tsimberidou AM
, Moulder SL, Koenig KH, Barcenas CH, Kee BK, Fogelman DR, Kopetz ES,
Meric-Bernstam F
,
Janku F
. PIK3CA mutations in plasma circulating tumor DNA predict survival and treatment outcomes in patients with advanced cancers. ESMO Open. 2021 10; 6(5):100230.
PMID:
34479035
; PMCID:
PMC8414046
.
Citations:
1
Translation:
Humans
Sun H, Cao S, Mashl RJ, Mo CK, Zaccaria S, Wendl MC, Davies SR, Bailey MH, Primeau TM, Hoog J, Mudd JL, Dean DA, Patidar R, Chen L, Wyczalkowski MA, Jayasinghe RG, Rodrigues FM, Terekhanova NV, Li Y, Lim KH, Wang-Gillam A, Van Tine BA, Ma CX, Aft R, Fuh KC, Schwarz JK, Zevallos JP, Puram SV, Dipersio JF, NCI PDXNet Consortium, Davis-Dusenbery B, Ellis MJ,
Lewis MT
, Davies MA, Herlyn M, Fang B,
Roth JA
, Welm AL, Welm BE,
Meric-Bernstam F
, Chen F, Fields RC, Li S, Govindan R, Doroshow JH, Moscow JA, Evrard YA, Chuang JH, Raphael BJ, Ding L. Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment. Nat Commun. 2021 08 24; 12(1):5086.
PMID:
34429404
; PMCID:
PMC8384880
.
Citations:
8
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Javle M
, Borad MJ, Azad NS, Kurzrock R, Abou-Alfa GK, George B, Hainsworth J,
Meric-Bernstam F
, Swanton C, Sweeney CJ, Friedman CF, Bose R, Spigel DR, Wang Y, Levy J, Schulze K, Cuchelkar V, Patel A, Burris H. Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study. Lancet Oncol. 2021 09; 22(9):1290-1300.
PMID:
34339623
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Harding JJ, Telli M, Munster P, Voss MH, Infante JR, DeMichele A, Dunphy M, Le MH, Molineaux C, Orford K, Parlati F, Whiting SH, Bennett MK,
Tannir NM
,
Meric-Bernstam F
. A Phase I Dose-Escalation and Expansion Study of Telaglenastat in Patients with Advanced or Metastatic Solid Tumors. Clin Cancer Res. 2021 09 15; 27(18):4994-5003.
PMID:
34285061
; PMCID:
PMC9401498
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Alhalabi O, Hahn AW, Msaouel P,
Meric-Bernstam F
, Wilson N,
Naing A
,
Piha-Paul S
,
Janku F
,
Pant S
, Yap TA,
Hong DS
,
Fu S
,
Karp D
, Beltran K, Campbell E, Le H, Campbell MT, Shah A,
Tannir NM
,
Siefker-Radtke A
,
Gao J
, Roszik J,
Subbiah V
. Validation of Prognostic Scores in Patients With Metastatic Urothelial Cancer Enrolling in Phase I Targeted Therapy or Next Generation Immunotherapy Trials. Clin Genitourin Cancer. 2022 02; 20(1):e16-e24.
PMID:
34362693
.
Citations:
Fields:
Neo
Neoplasms
Uro
Urology
Translation:
Humans
Elmore LC,
Kuerer HM
,
Barcenas CH
,
Smith BD
,
Miggins MV
,
Lucci A
,
Caudle AS
,
Meric-Bernstam F
,
Hunt KK
,
Teshome M
. Clinical Course of Breast Cancer Patients with Local-Regional Progression During Neoadjuvant Systemic Therapy. Ann Surg Oncol. 2021 Oct; 28(10):5477-5485.
PMID:
34247335
.
Citations:
1
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Ferrarotto R
, Sousa LG, Qing Y, Kaya D, Stephen B, Jain D,
Bell D
,
Pant S
,
Tsimberidou AM
,
Janku F
,
Blumenschein G
,
Glisson BS
, Ahnert JR,
Piha-Paul SA
, Lee JJ, Wong MK,
Lu C
,
Meric-Bernstam F
,
Naing A
. Pembrolizumab in Patients with Refractory Cutaneous Squamous Cell Carcinoma: A Phase?II Trial. Adv Ther. 2021 08; 38(8):4581-4591.
PMID:
34241781
.
Citations:
1
Fields:
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Shariati M, Evans KW, Zheng X, Bristow CA, Ng PK, Rizvi YQ,
Tapia C
, Yang F, Carugo A, Heffernan TP, Peoples MD, Tripathy D,
Meric-Bernstam F
. Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations. Oncogene. 2021 07; 40(26):4425-4439.
PMID:
34108622
.
Citations:
1
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Xu M,
Tapia C
,
Hajjar J
,
Sabir S
,
Colen R
,
Nagarajan P
,
Aung PP
, Gong J, Rodon J,
Fu S
, Stephen B, Roy-Chowdhuri S, Le H, Yang V, Zarifa A,
Abdelsalam ME
,
Jhingran A
,
Javle M
,
Pant S
,
Carter B
, Milton DR, Sun R,
Karp DD
,
Koay EJ
, Yang Y,
Wistuba II
,
Hwu P
,
Meric-Bernstam F
,
Naing A
. Implementation of a Novel Web-Based Lesion Selection Tool to Improve Acquisition of Tumor Biopsy Specimens. J Immunother Precis Oncol. 2021 May; 4(2):45-52.
PMID:
35663531
; PMCID:
PMC9153261
.
Citations:
3
Piha-Paul SA
, Dumbrava EE, Nair BC, Xiong W, Xu L, Mostorino R,
Subbiah V
,
Tannir N
,
Fu S
,
Naing A
,
Janku F
,
Karp DD
,
Patel S
, Daw NC,
Hong D
,
Meric-Bernstam F
, Zinner R. A Phase I Trial of the MET/ALK/ROS1 Inhibitor Crizotinib Combined with the VEGF Inhibitor Pazopanib in Patients with Advanced Solid Malignancies. Onco Targets Ther. 2021; 14:3037-3049.
PMID:
33994796
; PMCID:
PMC8114359
.
Citations:
2
Translation:
CT
Clinical Trials
Woo XY, Giordano J, Srivastava A, Zhao ZM, Lloyd MW, de Bruijn R, Suh YS, Patidar R, Chen L, Scherer S, Bailey MH, Yang CH, Cortes-Sanchez E, Xi Y, Wang J, Wickramasinghe J, Kossenkov AV, Rebecca VW, Sun H, Mashl RJ, Davies SR, Jeon R, Frech C, Randjelovic J, Rosains J, Galimi F, Bertotti A, Lafferty A, O'Farrell AC, Modave E, Lambrechts D, Ter Brugge P, Marangoni E, El Botty R, Kim H, Kim JI, Yang HK, Lee C, Dean DA, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, Welm BE,
Lewis MT
, Fang B,
Roth JA
,
Meric-Bernstam F
, Herlyn M, Davies MA, Ding L, Li S, Govindan R, Isella C, Moscow JA, Trusolino L, Byrne AT, Jonkers J, Bult CJ, Medico E, Chuang JH, PDXNET Consortium, EurOPDX Consortium, Serra V. Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet. 2021 May; 53(5):761.
PMID:
33608693
; PMCID:
PMC8110476
.
Citations:
1
Fields:
Gen
Genetics
Thein KZ,
Piha-Paul SA
,
Tsimberidou A
,
Karp DD
,
Janku F
, Zarifa A, Shah J, Bean S, McQuinn L, Gong J,
Colen R
,
Carter BW
,
Subbiah V
, Ogbonna DC,
Pant S
,
Meric-Bernstam F
,
Naing A
, Milton DR. Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study. Invest New Drugs. 2021 10; 39(5):1357-1365.
PMID:
33909232
; PMCID:
PMC8542012
.
Citations:
1
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Huey RW,
George GC
, Phillips P, White R,
Fu S
,
Janku F
,
Karp DD
,
Naing A
,
Piha-Paul S
,
Subbiah V
,
Tsimberidou AM
,
Pant S
, Yap TA, Rodon J,
Meric-Bernstam F
,
Shih YT
,
Hong DS
. Patient-Reported Out-of-Pocket Costs and Financial Toxicity During Early-Phase Oncology Clinical Trials. Oncologist. 2021 07; 26(7):588-596.
PMID:
33783054
; PMCID:
PMC8265355
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Smyth LM, Batist G,
Meric-Bernstam F
, Kabos P, Spanggaard I, Jhaveri K, Varga A, Wong A, Schram AM, Ambrose H, Carr TH, de Bruin EC, Salinas-Souza C, Foxley A, Hauser J, Lindemann JPO, Maudsley R, McEwen R, Moschetta M, Nikolaou M, Schiavon G, Razavi P, Banerji U, Hyman DM, Chandarlapaty S, Lluch A, Baselga J. Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer. NPJ Breast Cancer. 2021 Apr 16; 7(1):44.
PMID:
33863913
; PMCID:
PMC8052445
.
Citations:
8
Yap TA, Johnson A,
Meric-Bernstam F
. Precision Medicine in Oncology-Toward the Integrated Targeting of Somatic and Germline Genomic Aberrations. JAMA Oncol. 2021 04 01; 7(4):507-509.
PMID:
33630035
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Akcakanat A
, Zheng X, Cruz Pico CX, Kim TB, Chen K,
Korkut A
,
Sahin A
, Holla V, Tarco E, Singh G,
Damodaran S
,
Mills GB
, Gonzalez-Angulo AM,
Meric-Bernstam F
. Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer. Clin Cancer Res. 2021 06 01; 27(11):3243-3252.
PMID:
33782032
; PMCID:
PMC8172429
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hegde A, Jayaprakash P, Couillault CA,
Piha-Paul S
,
Karp D
, Rodon J,
Pant S
,
Fu S
, Dumbrava EE, Yap TA,
Subbiah V
, Bhosale P,
Coarfa C
, Higgins JP, Williams ET, Wilson TF, Lim J,
Meric-Bernstam F
, Sumner E, Zain H, Nguyen D, Nguyen LM, Rajapakshe K,
Curran MA
,
Hong DS
. A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies. Clin Cancer Res. 2021 06 01; 27(11):3050-3060.
PMID:
33771853
; PMCID:
PMC8172466
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Minussi DC, Nicholson MD, Ye H, Davis A, Wang K, Baker T, Tarabichi M, Sei E, Du H, Rabbani M, Peng C, Hu M, Bai S, Lin YW, Schalck A,
Multani A
, Ma J, McDonald TO, Casasent A, Barrera A, Chen H, Lim B,
Arun B
,
Meric-Bernstam F
, Van Loo P, Michor F,
Navin NE
. Breast tumours maintain a reservoir of subclonal diversity during expansion. Nature. 2021 04; 592(7853):302-308.
PMID:
33762732
; PMCID:
PMC8049101
.
Citations:
24
Fields:
Sci
Science
Translation:
Humans
Cells
Tsimberidou AM
,
Hong DS
,
Fu S
,
Karp DD
,
Piha-Paul S
,
Kies MS
,
Ravi V
,
Subbiah V
, Patel SM,
Tu SM
,
Janku F
,
Heymach J
, Johnson A, Cartwright C, Zhao L, Zhang J,
Berry DA
,
Vining DJ
,
Futreal A
, Miller VA,
Meric-Bernstam F
. Precision medicine: preliminary results from the Initiative for Molecular Profiling and Advanced Cancer Therapy 2 (IMPACT2) study. NPJ Precis Oncol. 2021 Mar 19; 5(1):21.
PMID:
33742104
; PMCID:
PMC7979841
.
Citations:
2
Hajjar J
,
Mendoza T
, Zhang L, Fu S,
Piha-Paul SA
,
Hong DS
,
Janku F
,
Karp DD
, Ballhausen A, Gong J, Zarifa A, Peterson CB,
Meric-Bernstam F
, Jenq R,
Naing A
. Associations between the gut microbiome and fatigue in cancer patients. Sci Rep. 2021 03 12; 11(1):5847.
PMID:
33712647
; PMCID:
PMC7954807
.
Citations:
7
Fields:
Sci
Science
Translation:
Humans
Cells
Cascone T, Sacks RL, Subbiah IM, Drobnitzky N,
Piha-Paul SA
, Hong DS, Hess KR, Amini B, Bhatt T, Fu S, Naing A,
Janku F
,
Karp D
, Falchook GS, Conley AP, Sherman SI,
Meric-Bernstam F
, Ryan AJ,
Heymach JV
, Subbiah V. Safety and activity of vandetanib in combination with everolimus in patients with advanced solid tumors: a phase I study. ESMO Open. 2021 04; 6(2):100079.
PMID:
33721621
; PMCID:
PMC7973128
.
Citations:
1
Translation:
Humans
CT
Clinical Trials
DiPeri TP,
Javle MM
,
Meric-Bernstam F
. Next generation sequencing for biliary tract cancers. Expert Rev Gastroenterol Hepatol. 2021 May; 15(5):471-474.
PMID:
33641586
; PMCID:
PMC8172427
.
Citations:
2
Fields:
Gas
Gastroenterology
Translation:
Humans
Pairawan S,
Zhao M
, Yuca E, Annis A, Evans K, Sutton D, Carvajal L, Ren JG, Santiago S, Guerlavais V,
Akcakanat A
,
Tapia C
, Yang F, Bose PSC, Zheng X, Dumbrava EI, Aivado M,
Meric-Bernstam F
. First in class dual MDM2/MDMX inhibitor ALRN-6924 enhances antitumor efficacy of chemotherapy in TP53 wild-type hormone receptor-positive breast cancer models. Breast Cancer Res. 2021 03 04; 23(1):29.
PMID:
33663585
; PMCID:
PMC7934277
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Cleary JM, Wang V, Heist RS,
Kopetz ES
, Mitchell EP, Zwiebel JA, Kapner KS, Chen HX, Li S, Gray RJ, McShane LM, Rubinstein LV, Patton DR,
Meric-Bernstam F
, Dillmon MS, Williams PM,
Hamilton SR
, Conley BA, Aguirre AJ, O'Dwyer PJ, Harris LN, Arteaga CL, Chen AP, Flaherty KT. Differential Outcomes in Codon 12/13 and Codon 61 NRAS-Mutated Cancers in the Phase II NCI-MATCH Trial of Binimetinib in Patients with NRAS-Mutated Tumors. Clin Cancer Res. 2021 06 01; 27(11):2996-3004.
PMID:
33637626
; PMCID:
PMC8542423
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Subbiah V
, Shen T, Tetzlaff M, Weissferdt A, Byers LA, Cascone T, Behrang A,
Meric-Bernstam F
, Mooers BHM, Rothenberg SM, Ebata K, Wu J. Patient-driven discovery and post-clinical validation of NTRK3 fusion as an acquired resistance mechanism to selpercatinib in RET fusion-positive lung cancer. Ann Oncol. 2021 06; 32(6):817-819.
PMID:
33617938
; PMCID:
PMC8119360
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Tsimberidou AM
, Vo HH,
Subbiah V
,
Janku F
,
Piha-Paul S
, Yilmaz B, Gong J, Naqvi MF,
Tu SM
, Campbell M,
Meric-Bernstam F
,
Naing A
. Pembrolizumab in Patients with Advanced Metastatic Germ Cell Tumors. Oncologist. 2021 07; 26(7):558-e1098.
PMID:
33491277
; PMCID:
PMC8265349
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Chen AP, Kummar S, Moore N, Rubinstein LV, Zhao Y, Williams PM, Palmisano A, Sims D, O'Sullivan Coyne G, Rosenberger CL, Simpson M,
Raghav KPS
,
Meric-Bernstam F
, Leong S, Waqar S, Foster JC, Das B, Karlovich C, Lih CJ, Polley E, Simon R, Li MC, Piekarz R, Doroshow JH, Konat? MM. Molecular Profiling-Based Assignment of Cancer Therapy (NCI-MPACT): A Randomized Multicenter Phase II Trial. JCO Precis Oncol. 2021; 5.
PMID:
33928209
; PMCID:
PMC8078898
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Zhao M
, Scott S, Evans KW, Yuca E, Saridogan T, Zheng X, Wang H,
Korkut A
, Cruz Pico CX, Demirhan M, Kirby B, Kopetz S, Diala I, Lalani AS,
Piha-Paul S
,
Meric-Bernstam F
. Combining Neratinib with CDK4/6, mTOR, and MEK Inhibitors in Models of HER2-positive Cancer. Clin Cancer Res. 2021 03 15; 27(6):1681-1694.
PMID:
33414137
; PMCID:
PMC8075007
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Woo XY, Giordano J, Srivastava A, Zhao ZM, Lloyd MW, de Bruijn R, Suh YS, Patidar R, Chen L, Scherer S, Bailey MH, Yang CH, Cortes-Sanchez E, Xi Y, Wang J, Wickramasinghe J, Kossenkov AV, Rebecca VW, Sun H, Mashl RJ, Davies SR, Jeon R, Frech C, Randjelovic J, Rosains J, Galimi F, Bertotti A, Lafferty A, O'Farrell AC, Modave E, Lambrechts D, Ter Brugge P, Marangoni E, El Botty R, Kim H, Kim JI, Yang HK, Lee C, Dean DA, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, Welm BE,
Lewis MT
, Fang B,
Roth JA
,
Meric-Bernstam F
, Herlyn M, Davies MA, Ding L, Li S, Govindan R, Isella C, Moscow JA, Trusolino L, Byrne AT, Jonkers J, Bult CJ, Medico E, Chuang JH, PDXNET Consortium, EurOPDX Consortium, Serra V. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet. 2021 01; 53(1):86-99.
PMID:
33414553
; PMCID:
PMC7808565
.
Citations:
32
Fields:
Gen
Genetics
Translation:
Humans
Animals
Abdel-Wahab R, Yap TA, Madison R,
Pant S
,
Cooke M
, Wang K, Zhao H, Bekaii-Saab T, Karatas E,
Kwong LN
,
Meric-Bernstam F
, Borad M,
Javle M
. Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer. Sci Rep. 2020 12 16; 10(1):22087.
PMID:
33328484
; PMCID:
PMC7745036
.
Citations:
9
Fields:
Sci
Science
Translation:
Humans
Cells
Alhalabi O, Hahn AW, Msaouel P, Andreev-Drakhlin AY,
Meric-Bernstam F
,
Naing A
,
Piha-Paul S
, Filip J,
Pant S
, Yap TA,
Hong DS
,
Fu S
,
Karp D
, Campbell E, Le H, Campbell MT,
Shah AY
,
Tannir NM
,
Siefker-Radtke AO
,
Gao J
, Roszik J,
Subbiah V
. Molecular Profiling of Metastatic Bladder Cancer Early-Phase Clinical Trial Participants Predicts Patient Outcomes. Mol Cancer Res. 2021 03; 19(3):395-402.
PMID:
33323389
.
Citations:
1
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Meric-Bernstam F
, Larkin J, Tabernero J, Bonini C. Enhancing anti-tumour efficacy with immunotherapy combinations. Lancet. 2021 03 13; 397(10278):1010-1022.
PMID:
33285141
.
Citations:
46
Fields:
Med
Medicine (General)
Translation:
Humans
Naing A
,
Hajjar J
, Gulley JL, Atkins MB, Ciliberto G,
Meric-Bernstam F
,
Hwu P
. Strategies for improving the management of immune-related adverse events. J Immunother Cancer. 2020 12; 8(2).
PMID:
33310772
; PMCID:
PMC7735083
.
Citations:
19
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Zhang X, Zhang R, Chen H, Wang L, Ren C,
Pataer A
, Wu S,
Meng QH
,
Ha MJ
, Morris J, Xi Y, Wang J, Zhang J,
Gibbons DL
,
Heymach JV
,
Meric-Bernstam F
, Minna J,
Swisher SG
,
Roth JA
,
Fang B
. KRT-232 and navitoclax enhance trametinib's anti-Cancer activity in non-small cell lung cancer patient-derived xenografts with KRAS mutations. Am J Cancer Res. 2020; 10(12):4464-4475.
PMID:
33415011
; PMCID:
PMC7783771
.
Citations:
7
Singh P,
Scoggins ME
,
Sahin AA
,
Hwang RF
,
Kuerer HM
,
Caudle AS
,
Mittendorf EA
, Thompson AM,
Bedrosian I
,
Teshome M
,
DeSnyder SM
,
Meric-Bernstam F
,
Hunt KK
. Effectiveness and Safety of Magseed-localization for Excision of Breast Lesions: A Prospective, Phase IV Trial. Ann Surg Open. 2020 Dec; 1(2).
PMID:
34017965
; PMCID:
PMC8130552
.
Citations:
1
Subbiah V
, Shen T, Terzyan SS, Liu X, Hu X, Patel KP, Hu M, Cabanillas M, Behrang A,
Meric-Bernstam F
, Vo PTT, Mooers BHM, Wu J. Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations. Ann Oncol. 2021 02; 32(2):261-268.
PMID:
33161056
; PMCID:
PMC7883646
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Hahn AW, Alhalabi O, Msaouel P,
Meric-Bernstam F
,
Naing A
,
Jonasch E
,
Piha-Paul S
,
Hong D
,
Pant S
, Yap T, Campbell E, Le H,
Tannir NM
, Roszik J,
Subbiah V
. Validation of prognostic scoring systems for patients with metastatic renal cell carcinoma enrolled in phase I clinical trials. ESMO Open. 2020 11; 5(6):e001073.
PMID:
33229506
; PMCID:
PMC7684827
.
Citations:
Translation:
Humans
CT
Clinical Trials
Seligson ND, Warner JL, Dalton WS, Martin D, Miller RS, Patt D, Kehl KL, Palchuk MB, Alterovitz G, Wiley LK, Huang M, Shen F, Wang Y, Nguyen KA, Wong AF,
Meric-Bernstam F
,
Bernstam EV
, Chen JL. Recommendations for patient similarity classes: results of the AMIA 2019 workshop on defining patient similarity. J Am Med Inform Assoc. 2020 11 01; 27(11):1808-1812.
PMID:
32885823
; PMCID:
PMC7671612
.
Citations:
6
Fields:
Med
Medical Informatics
Translation:
Humans
Janku F
, Sakamuri D, Kato S, Huang HJ, Call SG,
Naing A
, Holley VR,
Patel SP
,
Amaria RN
, Falchook GS,
Piha-Paul SA
, Zinner RG,
Tsimberidou AM
,
Hong DS
,
Meric-Bernstam F
. Dose-escalation study of vemurafenib with sorafenib or crizotinib in patients with BRAF-mutated advanced cancers. Cancer. 2021 02 01; 127(3):391-402.
PMID:
33119140
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Ballhausen A, Wheler JJ,
Karp DD
,
Piha-Paul SA
,
Fu S
,
Pant S
,
Tsimberidou AM
,
Hong DS
,
Subbiah V
, Holley VR, Huang HJ,
Brewster AM
,
Koenig KB
,
Ibrahim NK
,
Meric-Bernstam F
,
Janku F
. Phase I Study of Everolimus, Letrozole, and Trastuzumab in Patients with Hormone Receptor-positive Metastatic Breast Cancer or Other Solid Tumors. Clin Cancer Res. 2021 03 01; 27(5):1247-1255.
PMID:
33115815
; PMCID:
PMC9011198
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Janku F
, Park H, Call SG, Madwani K,
Oki Y
,
Subbiah V
,
Hong DS
,
Naing A
, Velez-Bravo VM, Barnes TG,
Hagemeister FB
, Falchook GS,
Karp DD
, Wheler JJ,
Piha-Paul SA
, Garrido-Laguna I,
Shpall EJ
,
Fayad LE
,
Neelapu SS
,
Meric-Bernstam F
, Kurzrock R,
Fanale MA
. Safety and Efficacy of Vorinostat Plus Sirolimus or Everolimus in Patients with Relapsed Refractory Hodgkin Lymphoma. Clin Cancer Res. 2020 11 01; 26(21):5579-5587.
PMID:
33055173
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ai D,
Yao J
, Yang F,
Huo L
, Chen H, Lu W, Soto LMS, Jiang M, Raso MG, Wang S,
Bell D
, Liu J, Wang H,
Tan D
, Torres-Cabala C, Gan Q, Wu Y,
Albarracin C
,
Hung MC
,
Meric-Bernstam F
,
Wistuba II
,
Prieto VG
,
Sahin AA
, Ding Q. TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer. Mod Pathol. 2021 04; 34(4):710-719.
PMID:
33011748
.
Citations:
4
Fields:
Pat
Pathology
Translation:
Humans
Hegde A, Andreev-Drakhlin AY, Roszik J, Huang L, Liu S, Hess K,
Cabanillas M
,
Hu MI
,
Busaidy NL
,
Sherman SI
,
Dadu R
,
Grubbs EG
, Ali SM, Lee J, Elamin YY,
Simon GR
,
Blumenschein GR
,
Papadimitrakopoulou VA
,
Hong D
,
Meric-Bernstam F
,
Heymach J
,
Subbiah V
. Responsiveness to immune checkpoint inhibitors versus other systemic therapies in RET-aberrant malignancies. ESMO Open. 2020 10; 5(5):e000799.
PMID:
33097651
; PMCID:
PMC7590373
.
Citations:
10
Translation:
Humans
CT
Clinical Trials
Flaherty KT, Gray R, Chen A, Li S, Patton D, Hamilton SR, Williams PM, Mitchell EP, Iafrate AJ, Sklar J, Harris LN, McShane LM, Rubinstein LV, Sims DJ,
Routbort M
, Coffey B, Fu T, Zwiebel JA, Little RF, Marinucci D, Catalano R, Magnan R, Kibbe W, Weil C, Tricoli JV, Alexander B, Kumar S, Schwartz GK,
Meric-Bernstam F
, Lih CJ, McCaskill-Stevens W, Caimi P, Takebe N, Datta V, Arteaga CL, Abrams JS, Comis R, O'Dwyer PJ, Conley BA, NCI-MATCH Team. The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design. J Natl Cancer Inst. 2020 10 01; 112(10):1021-1029.
PMID:
31922567
; PMCID:
PMC7566320
.
Citations:
45
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Yap TA, Tan DSP, Terbuch A, Caldwell R, Guo C, Goh BC, Heong V, Haris NRM, Bashir S, Drew Y,
Hong DS
,
Meric-Bernstam F
, Wilkinson G, Hreiki J, Wengner AM, Bladt F, Schlicker A, Ludwig M, Zhou Y, Liu L, Bordia S, Plummer R, Lagkadinou E, de Bono JS. First-in-Human Trial of the Oral Ataxia Telangiectasia and RAD3-Related (ATR) Inhibitor BAY 1895344 in Patients with Advanced Solid Tumors. Cancer Discov. 2021 01; 11(1):80-91.
PMID:
32988960
; PMCID:
PMC9554790
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Hong DS
, Fakih MG, Strickler JH, Desai J, Durm GA, Shapiro GI, Falchook GS, Price TJ, Sacher A, Denlinger CS, Bang YJ, Dy GK, Krauss JC, Kuboki Y, Kuo JC, Coveler AL, Park K, Kim TW, Barlesi F, Munster PN, Ramalingam SS, Burns TF,
Meric-Bernstam F
, Henary H, Ngang J, Ngarmchamnanrith G, Kim J, Houk BE, Canon J, Lipford JR, Friberg G, Lito P, Govindan R, Li BT. KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors. N Engl J Med. 2020 09 24; 383(13):1207-1217.
PMID:
32955176
; PMCID:
PMC7571518
.
Citations:
272
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Mosele F, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M,
Meric-Bernstam F
, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, Remon J, Bi?che I, Andr? F. Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group. Ann Oncol. 2020 11; 31(11):1491-1505.
PMID:
32853681
.
Citations:
138
Fields:
Neo
Neoplasms
Translation:
Humans
Araya A, Zeng J, Johnson A, Shufean MA, Rodon J,
Meric-Bernstam F
,
Bernstam EV
. Rate of change in investigational treatment options: An analysis of reports from a large precision oncology decision support effort. Int J Med Inform. 2020 11; 143:104261.
PMID:
32889387
; PMCID:
PMC9131704
.
Citations:
1
Fields:
Med
Medical Informatics
Translation:
Humans
Subbiah V
, Erwin W,
Mawlawi O
, McCoy A, Wages D, Wheeler C,
Gonzalez-Lepera C
, Liu H,
Macapinlac H
,
Meric-Bernstam F
,
Hong DS
,
Pant S
, Le D,
Santos E
, Gonzalez J, Roszik J, Suzuki T, Subach RA, Madden T, Johansen M, Nomura F, Satoh H, Matsuura T, Kajita M, Nakamura E, Funase Y, Matsushima S,
Ravizzini G
. Phase I Study of P-cadherin-targeted Radioimmunotherapy with 90Y-FF-21101 Monoclonal Antibody in Solid Tumors. Clin Cancer Res. 2020 11 15; 26(22):5830-5842.
PMID:
32816889
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Oaknin A, Friedman CF, Roman LD, D'Souza A, Brana I, Goldman J, Alvarez EA, Boni V, ElNaggar AC, Passalacqua R, Do KTM, Santin AD, Keyvanjah K, Xu F, Eli LD, Lalani AS, Bryce RP, Hyman DM,
Meric-Bernstam F
, Solit DB, Monk BJ, Bidard FC. Neratinib in patients with HER2-mutant, metastatic cervical cancer: Findings from the phase 2 SUMMIT basket trial. Gynecol Oncol. 2020 10; 159(1):150-156.
PMID:
32723675
; PMCID:
PMC8336424
.
Citations:
4
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Bahleda R,
Meric-Bernstam F
, Goyal L, Tran B, He Y, Yamamiya I, Benhadji KA, Matos I, Arkenau HT. Phase I, first-in-human study of futibatinib, a highly selective, irreversible FGFR1-4 inhibitor in patients with advanced solid tumors. Ann Oncol. 2020 10; 31(10):1405-1412.
PMID:
32622884
; PMCID:
PMC9743148
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Negrao MV, Raymond VM, Lanman RB, Robichaux JP, He J, Nilsson MB, Ng PKS, Amador BE, Roarty EB, Nagy RJ, Banks KC, Zhu VW, Ng C, Chae YK, Clarke JM, Crawford JA,
Meric-Bernstam F
, Ignatius Ou SH, Gandara DR,
Heymach JV
, Bivona TG, McCoach CE. Molecular Landscape of BRAF-Mutant NSCLC Reveals an Association Between Clonality and Driver Mutations and Identifies Targetable Non-V600 Driver Mutations. J Thorac Oncol. 2020 10; 15(10):1611-1623.
PMID:
32540409
; PMCID:
PMC7529990
.
Citations:
9
Fields:
Neo
Neoplasms
Pul
Pulmonary Medicine
Translation:
Humans
Hong DS
, Parikh A, Shapiro GI,
Naing A
,
Meric-Bernstam F
, Reyderman L, Binder TA, Ren M, Liu M, Dayal S, Siu AY, Sachdev P, Xu L, Bhagawati-Prasad V, Tchakov I, Ooi CE, Bao X, Varga A, Ataman ?, Marabelle A. First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers. J Immunother Cancer. 2020 06; 8(1).
PMID:
32554609
; PMCID:
PMC7304851
.
Citations:
13
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Cao J, Hu J, Liu S,
Meric-Bernstam F
, Abdel-Wahab R, Xu J, Li Q, Yan M, Feng Y, Lin J, Zhao S, Wang J,
Kwong LN
, Hu J, Carapeto F, Borad MJ, Wang K,
Javle M
, Zhao H. Intrahepatic Cholangiocarcinoma: Genomic Heterogeneity Between Eastern and Western Patients. JCO Precis Oncol. 2020; 4.
PMID:
32923885
; PMCID:
PMC7446410
.
Citations:
14
Fields:
Neo
Neoplasms
Pawlik TM, Tyler DS, Sumer B,
Meric-Bernstam F
, Okereke IC, Beane JD, Dedhia PH, Ejaz A, McMasters KM, Tanabe KK. COVID-19 Pandemic and Surgical Oncology: Preserving the Academic Mission. Ann Surg Oncol. 2020 Aug; 27(8):2591-2599.
PMID:
32472408
; PMCID:
PMC7257352
.
Citations:
7
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Cells
PH
Public Health
Subbiah V
, Dumbrava EI, Jiang Y, Thein KZ,
Naing A
,
Hong DS
,
Fu S
,
Piha-Paul SA
,
Tsimberidou AM
,
Janku F
,
Meric-Bernstam F
, Kurzrock R, Falchook G. Dual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial. Exp Hematol Oncol. 2020; 9:7.
PMID:
32337094
; PMCID:
PMC7171918
.
Citations:
5
Owusu-Brackett N,
Zhao M
,
Akcakanat A
, Evans KW, Yuca E, Dumbrava EI,
Janku F
,
Meric-Bernstam F
. Targeting PI3K? alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss. Oncotarget. 2020 Mar 17; 11(11):969-981.
PMID:
32215185
; PMCID:
PMC7082117
.
Citations:
6
Fields:
Neo
Neoplasms
Robichaux JP, Elamin YY, Vijayan RSK, Nilsson MB, Hu L, He J, Zhang F, Pisegna M, Poteete A, Sun H, Li S, Chen T, Han H, Negrao MV, Ahnert JR, Diao L, Wang J, Le X,
Meric-Bernstam F
,
Routbort M
, Roeck B, Yang Z, Raymond VM, Lanman RB, Frampton GM, Miller VA, Schrock AB, Albacker LA, Wong KK, Cross JB,
Heymach JV
. Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity. Cancer Cell. 2020 Mar 16; 37(3):420.
PMID:
32183953
; PMCID:
PMC7241090
.
Citations:
4
Fields:
Neo
Neoplasms
Krishnamurthy S
,
Sabir S
, Ban K, Wu Y,
Sheth R
,
Tam A
,
Meric-Bernstam F
, Shaw K,
Mills G
, Bassett R,
Hamilton S
,
Hicks M
,
Gupta S
. Comparison of Real-Time Fluorescence Confocal Digital Microscopy With Hematoxylin-Eosin-Stained Sections of Core-Needle Biopsy Specimens. JAMA Netw Open. 2020 03 02; 3(3):e200476.
PMID:
32134465
; PMCID:
PMC7059022
.
Citations:
7
Fields:
Med
Medicine (General)
Translation:
Humans
Naing A
,
Meric-Bernstam F
, Stephen B,
Karp DD
,
Hajjar J
, Rodon Ahnert J,
Piha-Paul SA
,
Colen RR
,
Jimenez C
,
Raghav KP
,
Ferrarotto R
,
Tu SM
, Campbell M, Wang L, Sabir SH,
Tapia C
,
Bernatchez C
,
Frumovitz M
,
Tannir N
,
Ravi V
, Khan S, Painter JM, Abonofal A, Gong J, Alshawa A, McQuinn LM, Xu M, Ahmed S,
Subbiah V
,
Hong DS
,
Pant S
, Yap TA,
Tsimberidou AM
, Dumbrava EEI,
Janku F
,
Fu S
, Simon RM,
Hess KR
,
Varadhachary GR
,
Habra MA
. Phase 2 study of pembrolizumab in patients with advanced rare cancers. J Immunother Cancer. 2020 03; 8(1).
PMID:
32188704
; PMCID:
PMC7078933
.
Citations:
32
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Makawita S
,
Meric-Bernstam F
. Antibody-Drug Conjugates: Patient and Treatment Selection. Am Soc Clin Oncol Educ Book. 2020 Mar; 40:1-10.
PMID:
32213087
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Kreisberg JF, Ideker T,
Meric-Bernstam F
,
Mills G
. Prospecting whole cancer genomes. Nat Cancer. 2020 03; 1(3):273-275.
PMID:
35122032
.
Citations:
Translation:
Humans
Subbiah V
, Yang D, Velcheti V, Drilon A,
Meric-Bernstam F
. State-of-the-Art Strategies for Targeting RET-Dependent Cancers. J Clin Oncol. 2020 04 10; 38(11):1209-1221.
PMID:
32083997
; PMCID:
PMC7145587
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Humans
Subbiah V
, Puzanov I, Chau I, Lockhart AC, Raje NS,
Meric-Bernstam F
, Roszik J, Diamond EL, Riely GJ, Sherman EJ, Riehl T, Pitcher B, Hyman DM, Blay JY, Wolf J, Baselga J. Pan-Cancer Efficacy of Vemurafenib in BRAFV600-Mutant Non-Melanoma Cancers. Cancer Discov. 2020 05; 10(5):657-663.
PMID:
32029534
; PMCID:
PMC7196502
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Smyth LM, Zhou Q, Nguyen B, Yu C, Lepisto EM, Arnedos M, Hasset MJ, Lenoue-Newton ML, Blauvelt N, Dogan S, Micheel CM, Wathoo C, Horlings H, Hudecek J, Gross BE, Kundra R, Sweeney SM, Gao J, Schultz N, Zarski A, Gardos SM, Lee J, Sheffler-Collins S, Park BH, Sawyers CL, Levy M,
Meric-Bernstam F
, Bedard PL, Iasonos A, Schrag D, Hyman DM, AACR Project GENIE Consortium, Andr? F. Characteristics and Outcome of AKT1E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry. Cancer Discov. 2020 04; 10(4):526-535.
PMID:
31924700
; PMCID:
PMC7125034
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Pairawan S,
Hess KR
,
Janku F
, Sanchez NS, Mills Shaw KR,
Eng C
,
Damodaran S
,
Javle M
,
Kaseb AO
,
Hong DS
,
Subbiah V
,
Fu S
,
Fogelman DR
, Raymond VM, Lanman RB,
Meric-Bernstam F
. Cell-free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer. Clin Cancer Res. 2020 04 15; 26(8):1924-1931.
PMID:
31852833
; PMCID:
PMC7771658
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Myers AP, Konstantinopoulos PA, Barry WT, Luo W,
Broaddus RR
, Makker V, Drapkin R, Liu J, Doyle A, Horowitz NS,
Meric-Bernstam F
, Birrer M, Aghajanian C,
Coleman RL
,
Mills GB
, Cantley LC, Matulonis UA,
Westin SN
. Phase II, 2-stage, 2-arm, PIK3CA mutation stratified trial of MK-2206 in recurrent endometrial cancer. Int J Cancer. 2020 07 15; 147(2):413-422.
PMID:
31714586
; PMCID:
PMC7214201
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Zhao M
, Zhuo ML, Zheng X,
Su X
,
Meric-Bernstam F
. Correction: FGFR1? is a driver isoform of FGFR1 alternative splicing in breast cancer cells. Oncotarget. 2019 Dec 10; 10(65):7014-7015.
PMID:
31857856
; PMCID:
PMC6916757
.
Citations:
Fields:
Neo
Neoplasms
Kurzrock R, Bowles DW, Kang H,
Meric-Bernstam F
, Hainsworth J, Spigel DR, Bose R, Burris H, Sweeney CJ, Beattie MS, Blotner S, Schulze K, Cuchelkar V, Swanton C. Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study. Ann Oncol. 2020 03; 31(3):412-421.
PMID:
32067683
; PMCID:
PMC9743163
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Smyth LM,
Piha-Paul SA
, Won HH, Schram AM, Loi S, Lu J, Shapiro GI, Juric D, Mayer IA, Arteaga CL, de la Fuente MI, Brufksy AM, Spanggaard I, Arnedos M, Boni V, Sohn J, Schwartzberg LS, Gorelick AN, Lanman RB, Nagy RJ, Ulaner GA, Chandarlapaty S, Jhaveri K, Gavrila EI, Zimel C, Selcuklu SD, Melcer M, Samoila A, Cai Y, Scaltriti M, Mann G, Xu F, Eli LD, Dujka M, Lalani AS, Bryce R, Taylor BS, Solit DB,
Meric-Bernstam F
, Hyman DM, Saura C, Mau-S?rensen M, Moreno V, Gonz?lez-Farr? X, Cervantes A, Bidard FC, Baselga J. Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer. Cancer Discov. 2020 02; 10(2):198-213.
PMID:
31806627
; PMCID:
PMC7007377
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Yang P,
Javle M
, Pang F, Zhao W, Abdel-Wahab R, Chen X,
Meric-Bernstam F
, Chen H, Borad MJ, Liu Y, Zou C, Mu S, Xing Y, Wang K, Peng C, Che X. Somatic genetic aberrations in gallbladder cancer: comparison between Chinese and US patients. Hepatobiliary Surg Nutr. 2019 Dec; 8(6):604-614.
PMID:
31929987
; PMCID:
PMC6943012
.
Citations:
18
Raghav K
, Loree JM, Morris JS,
Overman MJ
, Yu R,
Meric-Bernstam F
,
Menter D
, Korphaisarn K, Kee B, Muranyi A, Singh S,
Routbort M
, Chen K, Shaw KRM, Katkhuda R, Shanmugam K,
Maru D
, Fakih M, Kopetz S. Validation of HER2 Amplification as a Predictive Biomarker for Anti-Epidermal Growth Factor Receptor Antibody Therapy in Metastatic Colorectal Cancer. JCO Precis Oncol. 2019 Dec; 3:1-13.
PMID:
35100667
.
Citations:
Fields:
Neo
Neoplasms
Piha-Paul SA
, Taylor MH, Spitz D, Schwartzberg L, Beck JT, Bauer TM,
Meric-Bernstam F
, Purkayastha D, Karpiak L, Szpakowski S, Braiteh F. Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study. Oncotarget. 2019 Nov 05; 10(60):6526-6535.
PMID:
31741715
; PMCID:
PMC6849647
.
Citations:
6
Fields:
Neo
Neoplasms
Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S,
Lazar AJ
,
Pant S
,
Meric-Bernstam F
. Overview of the TREC 2019 Precision Medicine Track. Text Retr Conf. 2019 Nov; 1250.
PMID:
34849512
; PMCID:
PMC8629155
.
Citations:
1
Dumbrava EEI, Balaji K,
Raghav K
, Hess K,
Javle M
, Blum-Murphy M,
Ajani J
, Kopetz S,
Broaddus R
,
Routbort M
, Demirhan M, Zheng X,
Pant S
,
Tsimberidou AM
,
Subbiah V
,
Hong DS
, Rodon J, Shaw KM,
Piha-Paul SA
,
Meric-Bernstam F
. Targeting ERBB2 (HER2) Amplification Identified by Next-Generation Sequencing in Patients With Advanced or Metastatic Solid Tumors Beyond Conventional Indications. JCO Precis Oncol. 2019; 3.
PMID:
32923865
; PMCID:
PMC7446516
.
Citations:
4
Fields:
Neo
Neoplasms
Shariati M,
Meric-Bernstam F
. Targeting AKT for cancer therapy. Expert Opin Investig Drugs. 2019 Nov; 28(11):977-988.
PMID:
31594388
; PMCID:
PMC6901085
.
Citations:
42
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Robichaux JP, Elamin YY, Vijayan RSK, Nilsson MB, Hu L, He J, Zhang F, Pisegna M, Poteete A, Sun H, Li S, Chen T, Han H, Negrao MV, Ahnert JR, Diao L, Wang J, Le X,
Meric-Bernstam F
,
Routbort M
, Roeck B, Yang Z, Raymond VM, Lanman RB, Frampton GM, Miller VA, Schrock AB, Albacker LA, Wong KK, Cross JB,
Heymach JV
. Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity. Cancer Cell. 2019 10 14; 36(4):444-457.e7.
PMID:
31588020
; PMCID:
PMC6944069
.
Citations:
40
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
CT
Clinical Trials
Kim SB,
Meric-Bernstam F
, Kalyan A, Babich A, Liu R, Tanigawa T, Sommer A, Osada M, Reetz F, Laurent D, Wittemer-Rump S, Berlin J. First-in-Human Phase I Study of Aprutumab Ixadotin, a Fibroblast Growth Factor Receptor 2 Antibody-Drug Conjugate (BAY 1187982) in Patients with Advanced Cancer. Target Oncol. 2019 10; 14(5):591-601.
PMID:
31502117
; PMCID:
PMC6797631
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Creasy CA, Singh G,
Tapia C
, Xu M, Stephen B,
Sabir S
,
Meric-Bernstam F
,
Haymaker C
,
Bernatchez C
,
Naing A
, Forget MA. Exposure to anti-PD-1 causes functional differences in tumor-infiltrating lymphocytes in rare solid tumors. Eur J Immunol. 2019 12; 49(12):2245-2251.
PMID:
31532833
.
Citations:
2
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
CT
Clinical Trials
Kahle MP, Bailey AM, Wathoo C, Balaji K, Demirhan ME, Yang D,
Javle M
,
Kaseb A
,
Eng C
,
Subbiah V
,
Janku F
, Raymond VM, Lanman RB, Mills Shaw KR,
Meric-Bernstam F
, S?nchez NS. Identification of Actionable Genomic Alterations Using Circulating Cell-Free DNA. JCO Precis Oncol. 2019; 3.
PMID:
32923868
; PMCID:
PMC7448805
.
Citations:
3
Fields:
Neo
Neoplasms
Ulaner GA,
Piha-Paul SA
, Mayer I, Quinn D, Jhaveri K, Stone B, Shahin S, Mann G, Dujka M, Bryce R,
Meric-Bernstam F
, Solit DB, Hyman DM, Saura C. Impact of FDG PET Imaging for Expanding Patient Eligibility and Measuring Treatment Response in a Genome-Driven Basket Trial of the Pan-HER Kinase Inhibitor, Neratinib. Clin Cancer Res. 2019 12 15; 25(24):7381-7387.
PMID:
31548342
; PMCID:
PMC7418635
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Habra MA
, Stephen B, Campbell M, Hess K,
Tapia C
, Xu M, Rodon Ahnert J,
Jimenez C
, Lee JE,
Perrier ND
, Boraddus RR,
Pant S
,
Subbiah V
,
Hong DS
, Zarifa A,
Fu S
,
Karp DD
,
Meric-Bernstam F
,
Naing A
. Phase II clinical trial of pembrolizumab efficacy and safety in advanced adrenocortical carcinoma. J Immunother Cancer. 2019 09 18; 7(1):253.
PMID:
31533818
; PMCID:
PMC6751592
.
Citations:
32
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Eterovic AK
, Zheng X, Liu S, Chen K,
Mills GB
,
Meric-Bernstam F
, Lluch A, Gonz?lez-Angulo AM, Casadevall D, Mart?nez de Due?as E, Guerrero-Zotano ?, P?rez R, Chac?n JI, Antol?n S, Blancas I, L?pez-Serra P, Carrasco E, Caballero R, Prat A, Rojo F, Gonzalez-Perez A, Albanell J. Dynamic clonal remodelling in breast cancer metastases is associated with subtype conversion. Eur J Cancer. 2019 10; 120:54-64.
PMID:
31491604
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Zeng J, Johnson A, Shufean MA, Kahle M, Yang D,
Woodman SE
, Vu T, Moorthy S, Holla V,
Meric-Bernstam F
. Operationalization of Next-Generation Sequencing and Decision Support for Precision Oncology. JCO Clin Cancer Inform. 2019 09; 3:1-12.
PMID:
31550176
; PMCID:
PMC6874004
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Arango NP, Brusco L, Shaw KRM, Chen K,
Eterovic AK
, Holla V, Johnson A, Litzenburger B, Khotskaya YB, Sanchez N, Bailey A, Zheng X, Horombe C, Kopetz S, Farhangfar CJ,
Routbort M
,
Broaddus R
,
Bernstam EV
,
Mendelsohn J
,
Mills GB
,
Meric-Bernstam F
. Correction: A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory. Oncotarget. 2019 Aug 27; 10(50):5254.
PMID:
31497255
; PMCID:
PMC6718259
.
Citations:
Fields:
Neo
Neoplasms
Maymani H, Hess K, Groisberg R,
Hong DS
,
Naing A
,
Piha-Paul S
,
Janku F
,
Fu S
,
Tsimberidou AM
,
Pant S
,
Karp D
, Liu S, Sun M,
Heymach J
,
Simon G
,
Meric-Bernstam F
,
Subbiah V
. Corrigendum to "Predicting outcomes in patients with advanced non-small cell lung cancer enrolled in early phase immunotherapy trials" [Lung Cancer 120 (June) (2018) 137-141]. Lung Cancer. 2019 Oct; 136:158.
PMID:
31445783
.
Citations:
Fields:
Neo
Neoplasms
Owusu-Brackett N, Evans KW,
Akcakanat A
, Yuca E,
Tapia C
, Rizvi YQ, Dumbrava EI,
Janku F
,
Meric-Bernstam F
. TAK228 enhances antitumor activity of eribulin in triple negative breast cancer. Oncotarget. 2019 Aug 20; 10(49):5011-5019.
PMID:
31489111
; PMCID:
PMC6707945
.
Citations:
3
Fields:
Neo
Neoplasms
Dowling RJO, Sparano JA, Goodwin PJ, Bidard FC, Cescon DW, Chandarlapaty S, Deasy JO, Dowsett M, Gray RJ, Henry NL,
Meric-Bernstam F
, Perlmutter J, Sledge GW, Thorat MA, Bratman SV, Carey LA, Chang MC, DeMichele A, Ennis M, Jerzak KJ, Korde LA, Lohmann AE, Mamounas EP, Parulekar WR, Regan MM, Schramek D, Stambolic V, Whelan TJ, Wolff AC, Woodgett JR, Kalinsky K, Hayes DF. Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions. JNCI Cancer Spectr. 2019 Dec; 3(4):pkz049.
PMID:
32337478
; PMCID:
PMC7050024
.
Citations:
6
Fields:
Neo
Neoplasms
Dowling RJO, Kalinsky K, Bidard FC, Cescon DW, Chandarlapaty S, Deasy JO, Dowsett M, Gray RJ, Henry NL,
Meric-Bernstam F
, Perlmutter J, Sledge GW, Bratman SV, Chang MC, Ennis M, Jerzak KJ, Korde LA, Lohmann AE, Mamounas EP, Parulekar WR, Regan MM, Schramek D, Stambolic V, Thorat MA, Whelan TJ, Wolff AC, Woodgett JR, Sparano JA, Goodwin PJ, Hayes DF, Carey LA, DeMichele A. Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations. JNCI Cancer Spectr. 2019 Dec; 3(4):pkz050.
PMID:
32337479
; PMCID:
PMC7049988
.
Citations:
6
Fields:
Neo
Neoplasms
Avila M,
Meric-Bernstam F
. Next-generation sequencing for the general cancer patient. Clin Adv Hematol Oncol. 2019 Aug; 17(8):447-454.
PMID:
31449513
; PMCID:
PMC6739831
.
Citations:
6
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Kaseb AO
, Sen S, Kelley RK, Tan B, Bocobo AG, Lim KH, Abdel-Wahab R, Uemura M, Pestana RC, Qiao W, Xiao L, Morris J,
Amin HM
, Hassan MM,
Rashid A
, Banks KC, Lanman RB, Talasaz A, Mills-Shaw KR, George B, Haque A,
Raghav KPS
,
Wolff RA
,
Yao JC
,
Meric-Bernstam F
, Ikeda S, Kurzrock R, S?nchez NS. Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA. Clin Cancer Res. 2019 10 15; 25(20):6107-6118.
PMID:
31363003
; PMCID:
PMC9292132
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Ding Q, Chen H, Lim B,
Damodaran S
, Chen W, Tripathy D,
Piha-Paul S
,
Luthra R
,
Meric-Bernstam F
,
Sahin AA
. HER2 somatic mutation analysis in breast cancer: correlation with clinicopathological features. Hum Pathol. 2019 10; 92:32-38.
PMID:
31351155
.
Citations:
6
Fields:
Pat
Pathology
Translation:
Humans
Xing Y, Lin NU, Maurer MA, Chen H,
Mahvash A
,
Sahin A
,
Akcakanat A
, Li Y, Abramson V,
Litton J
, Chavez-MacGregor M,
Valero V
,
Piha-Paul SA
,
Hong D
,
Do KA
, Tarco E, Riall D,
Eterovic AK
, Wulf GM, Cantley LC,
Mills GB
, Doyle LA, Winer E, Hortobagyi GN, Gonzalez-Angulo AM,
Meric-Bernstam F
. Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation. Breast Cancer Res. 2019 07 05; 21(1):78.
PMID:
31277699
; PMCID:
PMC6612080
.
Citations:
52
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Zeng J, Shufean MA, Khotskaya Y, Yang D, Kahle M, Johnson A, Holla V, Mills Shaw KR,
Bernstam EV
,
Meric-Bernstam F
, S?nchez N. OCTANE: Oncology Clinical Trial Annotation Engine. JCO Clin Cancer Inform. 2019 07; 3:1-11.
PMID:
31265323
; PMCID:
PMC6873935
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Subbiah V
, Riely G, Hollebecque A, Felip E, Schuler M, Italiano A, Keedy V, Chau I, Puzanov I, Raje NS,
Meric-Bernstam F
, Makrutzki M, Riehl T, Pitcher B, Baselga J, Hyman DM, Gervais R, Blay JY, Gon?alves A. Efficacy of Vemurafenib in Patients With Non-Small-Cell Lung Cancer With BRAF V600 Mutation: An Open-Label, Single-Arm Cohort of the Histology-Independent VE-BASKET Study. JCO Precis Oncol. 2019; 3.
PMID:
32914022
; PMCID:
PMC7446432
.
Citations:
5
Fields:
Neo
Neoplasms
Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y,
Xia W
, Gong J, Pan Y, Chatterjee SS,
Yao J
, Evans KW, Nguyen TK, Park PK, Liu J,
Coarfa C
, Donepudi SR, Putluri V,
Putluri N
,
Sreekumar A
, Ambati CR, Hawke DH, Marks JR,
Gunaratne PH
,
Caudle AS
,
Sahin AA
, Hortobagyi GN,
Meric-Bernstam F
, Chen L,
Yu D
,
Hung MC
,
Curran MA
, Han L, Lin C, Yang L. Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nat Immunol. 2019 07; 20(7):835-851.
PMID:
31160797
; PMCID:
PMC6619502
.
Citations:
113
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Janku F
, Diamond EL, Goodman AM, Raghavan VK, Barnes TG, Kato S, Abdel-Wahab O, Durham BH,
Meric-Bernstam F
, Kurzrock R. Molecular Profiling of Tumor Tissue and Plasma Cell-Free DNA from Patients with Non-Langerhans Cell Histiocytosis. Mol Cancer Ther. 2019 06; 18(6):1149-1157.
PMID:
31015311
; PMCID:
PMC6548628
.
Citations:
6
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Wang F, Zhang S, Kim TB, Lin YY, Iqbal R, Wang Z, Mohanty V,
Sircar K
,
Karam JA
, Wendl MC,
Meric-Bernstam F
,
Weinstein JN
, Ding L,
Mills GB
, Chen K. Integrated transcriptomic-genomic tool Texomer profiles cancer tissues. Nat Methods. 2019 05; 16(5):401-404.
PMID:
30988467
; PMCID:
PMC7337246
.
Citations:
4
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Cells
Dumbrava EI, Brusco L, Daniels M, Wathoo C, Shaw K, Lu K, Zheng X, Strong L, Litton J,
Arun B
, Eterovic AK, Routbort M, Patel K, Qi Y,
Piha-Paul S
, Subbiah V, Hong D, Rodon J, Kopetz S,
Mendelsohn J
,
Mills GB
, Chen K,
Meric-Bernstam F
. Expanded analysis of secondary germline findings from matched tumor/normal sequencing identifies additional clinically significant mutations. JCO Precis Oncol. 2019; 3.
PMID:
31517177
; PMCID:
PMC6741435
.
Citations:
4
Fields:
Neo
Neoplasms
Zhang G, Wang Y, Chen B, Guo L, Cao L, Ren C, Wen L, Li K, Jia M, Li C, Mok H, Chen X, Wei G, Lin J, Zhang Z, Hou T, Han-Zhang H, Liu C, Liu H, Liu J, Balch CM,
Meric-Bernstam F
, Liao N. Characterization of frequently mutated cancer genes in Chinese breast tumors: a comparison of Chinese and TCGA cohorts. Ann Transl Med. 2019 Apr; 7(8):179.
PMID:
31168460
; PMCID:
PMC6526269
.
Citations:
24
You YN, Borras E, Chang K, Price BA, Mork M,
Chang GJ
,
Rodriguez-Bigas MA
,
Bednarski BK
,
Meric-Bernstam F
, Vilar E. Detection of Pathogenic Germline Variants Among Patients With Advanced Colorectal Cancer Undergoing Tumor Genomic Profiling for Precision Medicine. Dis Colon Rectum. 2019 04; 62(4):429-437.
PMID:
30730459
; PMCID:
PMC6415928
.
Citations:
10
Fields:
Gas
Gastroenterology
Translation:
Humans
Zheng S
, Alfaro-Munoz K, Wei W, Wang X, Wang F,
Eterovic AK
, Shaw KRM,
Meric-Bernstam F
,
Fuller GN
, Chen K, Verhaak RG,
Mills GB
, Yung WKA,
Weathers SP
,
de Groot JF
. Prospective Clinical Sequencing of Adult Glioma. Mol Cancer Ther. 2019 05; 18(5):991-1000.
PMID:
30926639
; PMCID:
PMC6497568
.
Citations:
5
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
George GC
, Iwuanyanwu EC, Buford AS,
Piha-Paul SA
,
Subbiah V
,
Fu S
,
Karp DD
,
Pant S
, Hinojosa CO,
Hess KR
,
Cleeland CS
,
Bernstam EV
,
Meric-Bernstam F
,
Hong DS
. Cancer-Related Internet Use and Its Association With Patient Decision Making and Trust in Physicians Among Patients in an Early Drug Development Clinic: A Questionnaire-Based Cross-Sectional Observational Study. J Med Internet Res. 2019 03 14; 21(3):e10348.
PMID:
30869638
; PMCID:
PMC6437608
.
Citations:
5
Fields:
Med
Medical Informatics
Translation:
Humans
Willauer AN, Liu Y, Pereira AAL, Lam M, Morris JS,
Raghav KPS
,
Morris VK
,
Menter D
,
Broaddus R
,
Meric-Bernstam F
,
Hayes-Jordan A
,
Huh W
,
Overman MJ
, Kopetz S, Loree JM. Clinical and molecular characterization of early-onset colorectal cancer. Cancer. 2019 06 15; 125(12):2002-2010.
PMID:
30854646
; PMCID:
PMC6583775
.
Citations:
59
Fields:
Neo
Neoplasms
Translation:
Humans
Meric-Bernstam F
, Hurwitz H,
Raghav KPS
, McWilliams RR, Fakih M, VanderWalde A, Swanton C, Kurzrock R, Burris H, Sweeney C, Bose R, Spigel DR, Beattie MS, Blotner S, Stone A, Schulze K, Cuchelkar V, Hainsworth J. Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study. Lancet Oncol. 2019 04; 20(4):518-530.
PMID:
30857956
; PMCID:
PMC6781620
.
Citations:
100
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Kopetz S, Mills Shaw KR, Lee JJ, Zhang J, Litzenburger B, Holla V, Kinyua W, Broaddus E, Daniels MS,
Meric-Bernstam F
,
Broaddus RR
. Use of a Targeted Exome Next-Generation Sequencing Panel Offers Therapeutic Opportunity and Clinical Benefit in a Subset of Patients With Advanced Cancers. JCO Precis Oncol. 2019; 3.
PMID:
32914008
; PMCID:
PMC7446317
.
Citations:
5
Fields:
Neo
Neoplasms
Hegde A,
Hong DS
, Behrang A, Ali SM, Juckett L,
Meric-Bernstam F
,
Subbiah V
. Activity of Brigatinib in Crizotinib and Ceritinib-Resistant ROS1- Rearranged Non-Small-Cell Lung Cancer. JCO Precis Oncol. 2019; 3.
PMID:
32775947
; PMCID:
PMC7410165
.
Citations:
1
Fields:
Neo
Neoplasms
Berry S, Giraldo N, Nguyen P, Green B, Xu H, Ogurtsova A, Soni A, Succaria F, Wang D, Roberts C, Stein J, Engle E, Pardoll D, Anders R, Cottrell T, Taube JM, Tran B, Voskoboynik M, Kuo J, Bang YL, Chung HC, Ahn MJ, Kim SW, Perera A, Freeman D, Achour I, Faggioni R, Xiao F, Ferte C, Lemech C,
Meric-Bernstam F
, Werner T, Hodi S, Messersmith W, Lewis N, Talluto C, Dostalek M, Tao A, McWhirter S, Trujillo D, Luke J, Xu C, Qi J, Qin G, Yu H, Jenkins M, Lo KM, Halle JP, Lan Y, Taylor M, Vogelzang N, Cohn A, Stepan D, Shumaker R, Dutcus C, Guo M, Schmidt E, Rasco D, Brose M, Di Simone C, Jain S, Richards D, Encarnacion C, Taylor M, Vogelzang N, Mier J, An J, Yang YY, Lee WH, Yang J, Kim JK, Kim HG, Paek SH, Lee JW, Woo J, Kim JB, Kwon H, Lim W, Paik NS, Kim YK, Moon BI,
Janku F
, Tan D, Martin-Liberal J, Takahashi S, Geva R, Gucalp A, Chen X, Subramanian K, Mataraza J, Wheler J, Bedard P. Correction to: 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018). J Immunother Cancer. 2019 Feb 13; 7(1):46.
PMID:
30760319
; PMCID:
PMC6373015
.
Citations:
6
Fields:
Neo
Neoplasms
The
Therapeutics
Voss MH, Heist RS, Cleary JM,
Meric-Bernstam F
,
Janku F
, Gandhi L, Iafrate AJ, Borger DR, Ishii N, Hu Y, Kirpicheva Y, Nicolas-Metral V, Pokorska-Bocci A, Vaslin Chessex A, Zanna C, Flaherty KT, Baselga J, Hierro C, Tabernero J. A Phase I, Open-Label, Multicenter, Dose-escalation Study of the Oral Selective FGFR Inhibitor Debio 1347 in Patients with Advanced Solid Tumors Harboring FGFR Gene Alterations. Clin Cancer Res. 2019 05 01; 25(9):2699-2707.
PMID:
30745300
; PMCID:
PMC9014845
.
Citations:
39
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Subbiah V
, Anderson PM, Kairemo K, Hess K,
Huh WW
,
Ravi V
, Daw NC,
Somaiah N
,
Ludwig JA
, Benjamin RS, Chawla S,
Hong DS
,
Meric-Bernstam F
,
Ravizzini G
,
Kleinerman E
,
Macapinlac H
,
Rohren E
. Alpha Particle Radium 223 Dichloride in High-risk Osteosarcoma: A Phase I Dose Escalation Trial. Clin Cancer Res. 2019 07 01; 25(13):3802-3810.
PMID:
30733229
; PMCID:
PMC6606382
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Hong DS
, Bauer TM, Lee JJ, Dowlati A, Brose MS, Farago AF, Taylor M, Shaw AT, Montez S,
Meric-Bernstam F
, Smith S, Tuch BB, Ebata K, Cruickshank S, Cox MC, Burris HA, Doebele RC. Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study. Ann Oncol. 2019 02 01; 30(2):325-331.
PMID:
30624546
; PMCID:
PMC6386027
.
Citations:
30
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Hyman DM,
Piha-Paul SA
, Won H, Rodon J, Saura C, Shapiro GI, Juric D, Quinn DI, Mayer IA, Loi S, Lockhart AC, Erinjeri JP, Scaltriti M, Ulaner GA, Patel J, Tang J, Beer H, Selcuklu SD, Hanrahan AJ, Bouvier N, Melcer M, Murali R, Schram AM, Smyth LM, Jhaveri K, Li BT, Drilon A, Harding JJ, Iyer G, Taylor BS, Berger MF, Cutler RE, Xu F, Butturini A, Eli LD, Mann G, Farrell C, Lalani AS, Bryce RP, Arteaga CL,
Meric-Bernstam F
, Solit DB, Moreno V, Doger B, Boni V, Calvo E, Baselga J. Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers. Nature. 2019 02; 566(7745):E11-E12.
PMID:
30755741
.
Citations:
2
Fields:
Sci
Science
Fathiamini S, Johnson AM, Zeng J, Holla V, Sanchez NS,
Meric-Bernstam F
,
Bernstam EV
, Cohen T. Rapamycin?-?mTOR?+?BRAF?=?? Using relational similarity to find therapeutically relevant drug-gene relationships in unstructured text. J Biomed Inform. 2019 02; 90:103094.
PMID:
30615938
; PMCID:
PMC6386529
.
Citations:
Fields:
Med
Medical Informatics
Translation:
Humans
Zhao M
, Zhuo ML, Zheng X,
Su X
,
Meric-Bernstam F
. FGFR1? is a driver isoform of FGFR1 alternative splicing in breast cancer cells. Oncotarget. 2019 Jan 01; 10(1):30-44.
PMID:
30713601
; PMCID:
PMC6343755
.
Citations:
6
Fields:
Neo
Neoplasms
Buzdar AU
, Suman VJ,
Meric-Bernstam F
, Leitch AM, Ellis MJ, Boughey JC, Unzeitig GW, Royce ME,
Hunt KK
. Disease-Free and Overall Survival Among Patients With Operable HER2-Positive Breast Cancer Treated With Sequential vs Concurrent Chemotherapy: The ACOSOG Z1041 (Alliance) Randomized Clinical Trial. JAMA Oncol. 2019 01 01; 5(1):45-50.
PMID:
30193295
; PMCID:
PMC6331049
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Cuglievan B,
Subbiah V
, Wang H,
Morani A
,
Meric-Bernstam F
, Holla V,
Herzog CE
. Response to Mammalian Target of Rapamycin-Based Therapy and Incidental Finding of Lynch Syndrome in a Patient With Solid Pseudopapillary Neoplasm of the Pancreas With AKT1_E17K Mutation. JCO Precis Oncol. 2018; 2.
PMID:
31650099
; PMCID:
PMC6812497
.
Citations:
Fields:
Neo
Neoplasms
Tevis SE, Bassett R,
Bedrosian I
, Barcenas CH, Black DM, Caudle AS,
DeSnyder SM
,
Fitzsullivan E
, Hunt KK,
Kuerer HM
, Lucci A,
Meric-Bernstam F
, Mittendorf EA, Park K, Teshome M, Thompson AM, Hwang RF. OncotypeDX Recurrence Score Does Not Predict Nodal Burden in Clinically Node Negative Breast Cancer Patients. Ann Surg Oncol. 2019 Mar; 26(3):815-820.
PMID:
30556120
.
Citations:
4
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
George GC
, Buford A, Hess K,
Piha-Paul SA
, Zinner R,
Subbiah V
, Hinojosa C,
Cleeland CS
,
Meric-Bernstam F
,
Bernstam EV
,
Hong DS
. Cancer-Related Internet Use and Online Social Networking Among Patients in an Early-Phase Clinical Trials Clinic at a Comprehensive Cancer Center. JCO Clin Cancer Inform. 2018 12; 2:1-14.
PMID:
30652565
; PMCID:
PMC6874009
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Loree JM, Bailey AM, Johnson AM, Yu Y, Wu W, Bristow CA, Davis JS, Shaw KR,
Broaddus R
, Banks KC, Lanman RB,
Meric-Bernstam F
,
Overman MJ
, Kopetz S,
Raghav K
. Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer. J Natl Cancer Inst. 2018 12 01; 110(12):1409-1417.
PMID:
29718453
; PMCID:
PMC6292791
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Meric-Bernstam F
, Johnson AM, Dumbrava EEI,
Raghav K
, Balaji K, Bhatt M,
Murthy RK
, Rodon J,
Piha-Paul SA
. Advances in HER2-Targeted Therapy: Novel Agents and Opportunities Beyond Breast and Gastric Cancer. Clin Cancer Res. 2019 04 01; 25(7):2033-2041.
PMID:
30442682
; PMCID:
PMC6445731
.
Citations:
76
Fields:
Neo
Neoplasms
Translation:
Humans
Bhatty M, Kato S,
Piha-Paul SA
,
Naing A
,
Subbiah V
, Huang HJ,
Karp DD
,
Tsimberidou AM
, Zinner RG,
Hwu WJ
,
Javle M
,
Patel SP
,
Hu MI
,
Varadhachary GR
,
Conley AP
, Ramzanali NM, Holley VR, Kurzrock R,
Meric-Bernstam F
, Kwang Chae Y, Kim KB, Falchook GS,
Janku F
. Phase 1 study of the combination of vemurafenib, carboplatin, and paclitaxel in patients with BRAF-mutated melanoma and other advanced malignancies. Cancer. 2019 02 01; 125(3):463-472.
PMID:
30383888
; PMCID:
PMC6340722
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Akcakanat A
,
Meric-Bernstam F
. MK-2206 window of opportunity study in breast cancer. Ann Transl Med. 2018 Nov; 6(Suppl 1):S57.
PMID:
30613632
; PMCID:
PMC6291614
.
Citations:
2
Jain A, Borad MJ, Kelley RK, Wang Y, Abdel-Wahab R,
Meric-Bernstam F
,
Baggerly KA
,
Kaseb AO
, Al-Shamsi HO, Ahn DH, DeLeon T, Bocobo AG, Bekaii-Saab T,
Shroff RT
,
Javle M
. Cholangiocarcinoma With FGFR Genetic Aberrations: A Unique Clinical Phenotype. JCO Precis Oncol. 2018 Nov; 2:1-12.
PMID:
35135097
.
Citations:
8
Fields:
Neo
Neoplasms
Slavin TP, Banks KC, Chudova D, Oxnard GR, Odegaard JI, Nagy RJ, Tsang KWK, Neuhausen SL, Gray SW, Cristofanilli M, Rodriguez AA, Bardia A, Leyland-Jones B, Janicek MF, Lilly M, Sonpavde G, Lee CE, Lanman RB,
Meric-Bernstam F
, Kurzrock R, Weitzel JN. Identification of Incidental Germline Mutations in Patients With Advanced Solid Tumors Who Underwent Cell-Free Circulating Tumor DNA Sequencing. J Clin Oncol. 2018 Oct 19; JCO1800328.
PMID:
30339520
; PMCID:
PMC6286162
.
Citations:
33
Fields:
Neo
Neoplasms
Keene KS, King T, Hwang ES,
Peng B
, McGuire KP,
Tapia C
, Zhang H, Bae S, Nakhlis F, Klauber-Demore N, Meszoely I, Sabel MS, Willey SC,
Eterovic AK
, Hudis C, Wolff AC, De Los Santos J, Thompson A,
Mills GB
,
Meric-Bernstam F
. Molecular determinants of post-mastectomy breast cancer recurrence. NPJ Breast Cancer. 2018; 4:34.
PMID:
30345349
; PMCID:
PMC6185974
.
Citations:
3
Subbiah V
, Sen S,
Hess KR
,
Janku F
,
Hong DS
,
Khatua S
,
Karp DD
, Munoz J, Falchook GS, Groisberg R,
Tsimberidou AM
,
Sherman SI
,
Hwu P
,
Meric-Bernstam F
. Phase I Study of the BRAF Inhibitor Vemurafenib in Combination With the Mammalian Target of Rapamycin Inhibitor Everolimus in Patients With BRAF-Mutated Malignancies. JCO Precis Oncol. 2018; 2.
PMID:
32913986
; PMCID:
PMC7446411
.
Citations:
4
Fields:
Neo
Neoplasms
Kono M, Fujii T, Matsuda N, Harano K, Chen H, Wathoo C, Joon AY, Tripathy D,
Meric-Bernstam F
,
Ueno NT
. Somatic mutations, clinicopathologic characteristics, and survival in patients with untreated breast cancer with bone-only and non-bone sites of first metastasis. J Cancer. 2018; 9(19):3640-3646.
PMID:
30310523
; PMCID:
PMC6171013
.
Citations:
13
Wang Y, Wang Z,
Piha-Paul S
,
Janku F
,
Subbiah V
, Shi N, Hess K,
Broaddus R
, Shan B,
Naing A
,
Hong D
,
Tsimberidou AM
,
Karp D
,
Lu C
, Papadimitrakopoulou V,
Heymach J
,
Meric-Bernstam F
,
Fu S
. Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer. Oncotarget. 2018 Sep 07; 9(70):33258-33270.
PMID:
30279957
; PMCID:
PMC6161801
.
Citations:
4
Fields:
Neo
Neoplasms
Chen X, Low KH, Alexander A, Jiang Y,
Karakas C
,
Hess KR
, Carey JPW, Bui TN, Vijayaraghavan S, Evans KW, Yi M, Ellis DC, Cheung KL, Ellis IO,
Fu S
,
Meric-Bernstam F
,
Hunt KK
,
Keyomarsi K
. Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition. Clin Cancer Res. 2018 12 15; 24(24):6594-6610.
PMID:
30181387
; PMCID:
PMC6317865
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Dembla V,
Somaiah N
, Barata P, Hess K,
Fu S
,
Janku F
,
Karp DD
,
Naing A
,
Piha-Paul SA
,
Subbiah V
,
Tsimberidou AM
, Shaw K,
Meric-Bernstam F
,
Hong DS
. Prevalence of MDM2 amplification and coalterations in 523 advanced cancer patients in the MD Anderson phase 1 clinic. Oncotarget. 2018 Sep 04; 9(69):33232-33243.
PMID:
30237864
; PMCID:
PMC6145698
.
Citations:
6
Fields:
Neo
Neoplasms
Basho RK, Yam C,
Gilcrease M
,
Murthy RK
, Helgason T,
Karp DD
,
Meric-Bernstam F
,
Hess KR
,
Valero V
,
Albarracin C
,
Litton JK
, Chavez-MacGregor M,
Hong D
, Kurzrock R, Hortobagyi GN,
Janku F
,
Moulder SL
. Comparative Effectiveness of an mTOR-Based Systemic Therapy Regimen in Advanced, Metaplastic and Nonmetaplastic Triple-Negative Breast Cancer. Oncologist. 2018 11; 23(11):1300-1309.
PMID:
30139837
; PMCID:
PMC6291334
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Fu S
, Wang Y,
Keyomarsi K
, Meric-Bernstein F. Strategic development of AZD1775, a Wee1 kinase inhibitor, for cancer therapy. Expert Opin Investig Drugs. 2018 09; 27(9):741-751.
PMID:
30102076
.
Citations:
21
Fields:
Dru
Drug Therapy
Translation:
Humans
Animals
Liang WS, Vergilio JA, Salhia B, Huang HJ,
Oki Y
, Garrido-Laguna I, Park H,
Westin JR
,
Meric-Bernstam F
, Fabrizio D, Miller VA, Stephens PJ,
Fanale MA
, Ross JS,
Janku F
. Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden. Oncologist. 2019 02; 24(2):219-228.
PMID:
30108156
; PMCID:
PMC6369943
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Arudra K, Patel R,
Tetzlaff MT
,
Hymes S
,
Subbiah V
,
Meric-Bernstam F
, Torres-Cabala C,
Aung PP
,
Nagarajan P
,
Diab A
,
Prieto VG
, Nelson K,
Curry JL
. Calcinosis cutis dermatologic toxicity associated with fibroblast growth factor receptor inhibitor for the treatment of Wilms tumor. J Cutan Pathol. 2018 Oct; 45(10):786-790.
PMID:
30021048
.
Citations:
5
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Liu L, Toung JM, Jassowicz AF, Vijayaraghavan R, Kang H, Zhang R, Kruglyak KM, Huang HJ, Hinoue T, Shen H, Salathia NS, Hong DS, Naing A, Subbiah V,
Piha-Paul SA
, Bibikova M, Granger G, Barnes B, Shen R, Gutekunst K, Fu S,
Tsimberidou AM
, Lu C, Eng C, Moulder SL, Kopetz ES, Amaria RN,
Meric-Bernstam F
, Laird PW, Fan JB,
Janku F
. Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification. Ann Oncol. 2018 06 01; 29(6):1445-1453.
PMID:
29635542
; PMCID:
PMC6005020
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Hainsworth JD,
Meric-Bernstam F
, Swanton C, Hurwitz H, Spigel DR, Sweeney C, Burris H, Bose R, Yoo B, Stein A, Beattie M, Kurzrock R. Reply to J.J. Tao et al. J Clin Oncol. 2018 08 10; 36(23):2451.
PMID:
29856693
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Ileana Dumbrava E,
Meric-Bernstam F
, Yap TA. Challenges with biomarkers in cancer drug discovery and development. Expert Opin Drug Discov. 2018 08; 13(8):685-690.
PMID:
29792354
.
Citations:
11
Fields:
Che
Chemistry Techniques
Pha
Pharmacology
Translation:
Humans
Eckhardt BL
, Gagliardi M, Iles L, Evans K,
Ivan C
, Liu X, Liu CG, Souza G, Rao A,
Meric-Bernstam F
,
Ueno NT
,
Bartholomeusz GA
. Clinically relevant inflammatory breast cancer patient-derived xenograft-derived ex vivo model for evaluation of tumor-specific therapies. PLoS One. 2018; 13(5):e0195932.
PMID:
29768500
; PMCID:
PMC5955489
.
Citations:
6
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Wang Z, Ng KS, Chen T, Kim TB, Wang F, Shaw K, Scott KL,
Meric-Bernstam F
,
Mills GB
, Chen K. Cancer driver mutation prediction through Bayesian integration of multi-omic data. PLoS One. 2018; 13(5):e0196939.
PMID:
29738578
; PMCID:
PMC5940219
.
Citations:
7
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Wang M, Liang L, Lei X,
Multani A
,
Meric-Bernstam F
,
Tripathy D
, Wu Y, Chen H, Zhang H. Evaluation of cMET aberration by immunohistochemistry and fluorescence in situ hybridization (FISH) in triple negative breast cancers. Ann Diagn Pathol. 2018 Aug; 35:69-76.
PMID:
29843069
.
Citations:
3
Fields:
Pat
Pathology
Translation:
Humans
Sen S, Kato S, Agarwal R,
Piha-Paul S
, Hess K,
Karp D
,
Janku F
,
Fu S
,
Naing A
,
Pant S
, Falchook G, Tang C, Wu X,
Ye Y
,
Tsimberidou A
,
Subbiah V
, Kurzrock R,
Byers L
,
Westin S
, Lim J, Bean S, Bass A, Nguyen L,
Meric-Bernstam F
,
Hong D
. Phase I study of nab-paclitaxel, gemcitabine, and bevacizumab in patients with advanced cancers. Br J Cancer. 2018 05; 118(11):1419-1424.
PMID:
29695765
; PMCID:
PMC5988803
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Meric-Bernstam F
, Zheng X, Shariati M,
Damodaran S
, Wathoo C, Brusco L, Demirhan ME,
Tapia C
,
Eterovic AK
, Basho RK,
Ueno NT
,
Janku F
,
Sahin A
, Rodon J,
Broaddus R
, Kim TB,
Mendelsohn J
, Mills Shaw KR, Tripathy D,
Mills GB
, Chen K. Survival Outcomes by TP53 Mutation Status in Metastatic Breast Cancer. JCO Precis Oncol. 2018; 2018.
PMID:
30035249
; PMCID:
PMC6050977
.
Citations:
19
Fields:
Neo
Neoplasms
Slosberg ED, Kang BP, Peguero J, Taylor M, Bauer TM, Berry DA, Braiteh F, Spira A,
Meric-Bernstam F
, Stein S,
Piha-Paul SA
, Salvado A. Signature program: a platform of basket trials. Oncotarget. 2018 Apr 20; 9(30):21383-21395.
PMID:
29765547
; PMCID:
PMC5940401
.
Citations:
15
Fields:
Neo
Neoplasms
Groisberg R,
Hong DS
, Roszik J,
Janku F
,
Tsimberidou AM
,
Javle M
,
Meric-Bernstam F
,
Subbiah V
. Clinical Next-Generation Sequencing for Precision Oncology in Rare Cancers. Mol Cancer Ther. 2018 07; 17(7):1595-1601.
PMID:
29654067
; PMCID:
PMC6310221
.
Citations:
11
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
Somaiah N
, Beird HC, Barbo A, Song J, Mills Shaw KR, Wang WL, Eterovic K, Chen K,
Lazar A
,
Conley AP
,
Ravi V
,
Hwu P
,
Futreal A
,
Simon G
,
Meric-Bernstam F
,
Hong D
. Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations. Oncotarget. 2018 Apr 13; 9(28):19891-19899.
PMID:
29731991
; PMCID:
PMC5929434
.
Citations:
7
Fields:
Neo
Neoplasms
Hong DS
, Moore K, Patel M, Grant SC, Burris HA, William WN, Jones S,
Meric-Bernstam F
, Infante J, Golden L, Zhang W, Martinez R, Wijayawardana S, Beckmann R, Lin AB,
Eng C
, Bendell J. Evaluation of Prexasertib, a Checkpoint Kinase 1 Inhibitor, in a Phase Ib Study of Patients with Squamous Cell Carcinoma. Clin Cancer Res. 2018 07 15; 24(14):3263-3272.
PMID:
29643063
; PMCID:
PMC6050086
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Maymani H, Hess K, Groisberg R,
Hong DS
,
Naing A
,
Piha-Paul S
,
Janku F
,
Fu S
,
Tsimberidou AM
,
Pant S
,
Karp D
, Liu S, Sun M,
Heymach J
,
Simon G
,
Meric-Bernstam F
,
Subbiah V
. Predicting outcomes in patients with advanced non-small cell lung cancer enrolled in early phase immunotherapy trials. Lung Cancer. 2018 06; 120:137-141.
PMID:
29748008
; PMCID:
PMC6204221
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
DiNardo CD
,
Routbort MJ
, Bannon SA,
Benton CB
,
Takahashi K
,
Kornblau SM
,
Luthra R
, Kanagal-Shamanna R,
Medeiros LJ
,
Garcia-Manero G
, M Kantarjian H, Futreal PA,
Meric-Bernstam F
,
Patel KP
. Improving the detection of patients with inherited predispositions to hematologic malignancies using next-generation sequencing-based leukemia prognostication panels. Cancer. 2018 07 01; 124(13):2704-2713.
PMID:
29682723
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Huang KL, Mashl RJ, Wu Y,
Ritter DI
, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Cancer Genome Atlas Research Network,
Lichtarge O
, Boutros PC, Raphael B,
Lazar AJ
, Zhang W, Wendl MC, Govindan R, Jain S,
Wheeler D
, Kulkarni S, Dipersio JF,
Meric-Bernstam F
, Chen K, Shmulevich I,
Plon SE
, Chen F, Ding L, Reimand J. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell. 2018 04 05; 173(2):355-370.e14.
PMID:
29625052
; PMCID:
PMC5949147
.
Citations:
239
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Dumbrava EI,
Meric-Bernstam F
. Personalized cancer therapy-leveraging a knowledge base for clinical decision-making. Cold Spring Harb Mol Case Stud. 2018 04; 4(2).
PMID:
29212833
; PMCID:
PMC5880252
.
Citations:
23
Fields:
Gen
Genetics
Translation:
Humans
Animals
Sun C, Yin J, Fang Y, Chen J, Jeong KJ, Chen X, Vellano CP, Ju Z, Zhao W, Zhang D,
Lu Y
,
Meric-Bernstam F
, Yap TA, Hattersley M, O'Connor MJ, Chen H, Fawell S,
Lin SY
, Peng G,
Mills GB
. BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency. Cancer Cell. 2018 03 12; 33(3):401-416.e8.
PMID:
29533782
; PMCID:
PMC5944839
.
Citations:
98
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ng PK, Li J, Jeong KJ, Shao S, Chen H, Tsang YH, Sengupta S, Wang Z, Bhavana VH, Tran R, Soewito S, Minussi DC, Moreno D, Kong K, Dogruluk T, Lu H, Tokheim C, Zhou DC, Johnson AM, Zeng J, Ip CKM, Ju Z, Wester M, Yu S, Li Y, Vellano CP, Karchin R, Ding L,
Lu Y
, Cheung LWT, Chen K, Shaw KR,
Meric-Bernstam F
, Scott KL,
Yi S
,
Sahni N
,
Liang H
,
Mills GB
, Gao J, Schultz N. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018 03 12; 33(3):450-462.e10.
PMID:
29533785
; PMCID:
PMC5926201
.
Citations:
78
Fields:
Neo
Neoplasms
Translation:
Humans
Janku F
, Yap TA,
Meric-Bernstam F
. Targeting the PI3K pathway in cancer: are we making headway? Nat Rev Clin Oncol. 2018 05; 15(5):273-291.
PMID:
29508857
.
Citations:
326
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Drilon A, Laetsch TW, Kummar S, DuBois SG, Lassen UN, Demetri GD, Nathenson M, Doebele RC, Farago AF, Pappo AS, Turpin B, Dowlati A, Brose MS, Mascarenhas L, Federman N, Berlin J, El-Deiry WS, Baik C, Deeken J, Boni V, Nagasubramanian R, Taylor M, Rudzinski ER,
Meric-Bernstam F
, Sohal DPS, Ma PC, Raez LE, Hechtman JF, Benayed R, Ladanyi M, Tuch BB, Ebata K, Cruickshank S, Ku NC, Cox MC, Hawkins DS,
Hong DS
, Hyman DM. Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children. N Engl J Med. 2018 02 22; 378(8):731-739.
PMID:
29466156
; PMCID:
PMC5857389
.
Citations:
643
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Sen S, Hess K,
Hong DS
,
Naing A
,
Piha-Paul S
,
Janku F
,
Fu S
,
Subbiah IM
, Liu H, Khanji R, Huang L, Moorthy S,
Karp DD
,
Tsimberidou A
,
Meric-Bernstam F
,
Subbiah V
. Development of a prognostic scoring system for patients with advanced cancer enrolled in immune checkpoint inhibitor phase 1 clinical trials. Br J Cancer. 2018 03 20; 118(6):763-769.
PMID:
29462132
; PMCID:
PMC5886120
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Kurnit KC, Dumbrava EEI, Litzenburger B, Khotskaya YB, Johnson AM, Yap TA, Rodon J, Zeng J, Shufean MA, Bailey AM, Holla V,
Mendelsohn J
, Shaw KM,
Bernstam EV
,
Mills GB
,
Meric-Bernstam F
, S?nchez NS. Precision Oncology Decision Support: Current Approaches and Strategies for the Future. Clin Cancer Res. 2018 06 15; 24(12):2719-2731.
PMID:
29420224
; PMCID:
PMC6004235
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Hyman DM,
Piha-Paul SA
, Won H, Rodon J, Saura C, Shapiro GI, Juric D, Quinn DI, Mayer IA, Loi S, Lockhart AC, Erinjeri JP, Scaltriti M, Ulaner GA, Patel J, Tang J, Beer H, Selcuklu SD, Hanrahan AJ, Bouvier N, Melcer M, Murali R, Schram AM, Smyth LM, Jhaveri K, Li BT, Drilon A, Harding JJ, Iyer G, Taylor BS, Berger MF, Cutler RE, Xu F, Butturini A, Eli LD, Mann G, Farrell C, Lalani AS, Bryce RP, Arteaga CL,
Meric-Bernstam F
, Solit DB, Moreno V, Doger B, Boni V, Calvo E, Baselga J. HER kinase inhibition in patients with HER2- and HER3-mutant cancers. Nature. 2018 02 08; 554(7691):189-194.
PMID:
29420467
; PMCID:
PMC5808581
.
Citations:
223
Fields:
Sci
Science
Translation:
Humans
CT
Clinical Trials
Hainsworth JD,
Meric-Bernstam F
, Swanton C, Hurwitz H, Spigel DR, Sweeney C, Burris H, Bose R, Yoo B, Stein A, Beattie M, Kurzrock R. Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study. J Clin Oncol. 2018 02 20; 36(6):536-542.
PMID:
29320312
.
Citations:
136
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Casasent AK, Schalck A, Gao R, Sei E, Long A, Pangburn W, Casasent T,
Meric-Bernstam F
,
Edgerton ME
,
Navin NE
. Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing. Cell. 2018 01 11; 172(1-2):205-217.e12.
PMID:
29307488
; PMCID:
PMC5766405
.
Citations:
140
Fields:
Cel
Cell Biology
Translation:
Humans
Groisberg R,
Hong DS
, Behrang A, Hess K,
Janku F
,
Piha-Paul S
,
Naing A
,
Fu S
, Benjamin R,
Patel S
,
Somaiah N
,
Conley A
,
Meric-Bernstam F
,
Subbiah V
. Characteristics and outcomes of patients with advanced sarcoma enrolled in early phase immunotherapy trials. J Immunother Cancer. 2017 12 19; 5(1):100.
PMID:
29254498
; PMCID:
PMC5735899
.
Citations:
41
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Fujii T, Matsuda N, Kono M, Harano K, Chen H,
Luthra R
, Roy-Chowdhuri S,
Sahin AA
, Wathoo C, Joon AY, Tripathy D,
Meric-Bernstam F
,
Ueno NT
. Prior systemic treatment increased the incidence of somatic mutations in metastatic breast cancer. Eur J Cancer. 2018 01; 89:64-71.
PMID:
29232568
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Strickler JH, Loree JM, Ahronian LG, Parikh AR, Niedzwiecki D, Pereira AAL, McKinney M, Korn WM, Atreya CE, Banks KC, Nagy RJ,
Meric-Bernstam F
, Lanman RB, Talasaz A, Tsigelny IF, Corcoran RB, Kopetz S. Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer. Cancer Discov. 2018 02; 8(2):164-173.
PMID:
29196463
; PMCID:
PMC5809260
.
Citations:
96
Fields:
Neo
Neoplasms
Translation:
Humans
Loree JM, Pereira AAL, Lam M, Willauer AN,
Raghav K
, Dasari A,
Morris VK
, Advani S,
Menter DG
,
Eng C
, Shaw K,
Broaddus R
,
Routbort MJ
, Liu Y, Morris JS,
Luthra R
,
Meric-Bernstam F
,
Overman MJ
,
Maru D
, Kopetz S. Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes. Clin Cancer Res. 2018 03 01; 24(5):1062-1072.
PMID:
29180604
; PMCID:
PMC5844818
.
Citations:
80
Fields:
Neo
Neoplasms
Translation:
Humans
Brusco LL, Wathoo C, Mills Shaw KR, Holla VR, Bailey AM, Johnson AM, Khotskaya YB, Litzenburger BC, Sanchez NS, Zeng J,
Bernstam EV
,
Eng C
,
Kee BK
,
Amaria RN
,
Routbort MJ
,
Mills GB
,
Mendelsohn J
,
Meric-Bernstam F
. Physician interpretation of genomic test results and treatment selection. Cancer. 2018 03 01; 124(5):966-972.
PMID:
29165790
; PMCID:
PMC5821595
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Dembla V, Groisberg R, Hess K,
Fu S
, Wheler J,
Hong DS
,
Janku F
, Zinner R,
Piha-Paul SA
,
Ravi V
, Benjamin RS,
Patel S
,
Somaiah N
,
Herzog CE
,
Karp DD
, Roszik J,
Meric-Bernstam F
,
Subbiah V
. Outcomes of patients with sarcoma enrolled in clinical trials of pazopanib combined with histone deacetylase, mTOR, Her2, or MEK inhibitors. Sci Rep. 2017 11 21; 7(1):15963.
PMID:
29162825
; PMCID:
PMC5698336
.
Citations:
14
Fields:
Sci
Science
Translation:
Humans
Cells
Fujii T,
Colen RR
, Bilen MA,
Hess KR
,
Hajjar J
,
Suarez-Almazor ME
, Alshawa A,
Hong DS
,
Tsimberidou A
,
Janku F
, Gong J, Stephen B,
Subbiah V
,
Piha-Paul SA
,
Fu S
,
Sharma P
,
Mendoza T
, Patel A,
Thirumurthi S
,
Sheshadri A
,
Meric-Bernstam F
,
Naing A
. Incidence of immune-related adverse events and its association with treatment outcomes: the MD Anderson Cancer Center experience. Invest New Drugs. 2018 08; 36(4):638-646.
PMID:
29159766
; PMCID:
PMC5962379
.
Citations:
58
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
Kurnit KC, Bailey AM, Zeng J, Johnson AM, Shufean MA, Brusco L, Litzenburger BC, Khotskaya YB, Holla V, Simpson A,
Mills GB
,
Mendelsohn J
,
Bernstam E
, Shaw K,
Meric-Bernstam F
, S?nchez NS. "Personalized Cancer Therapy": A Publicly Available Precision Oncology Resource. Cancer Res. 2017 11 01; 77(21):e123-e126.
PMID:
29092956
; PMCID:
PMC5774617
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Evans KW, Yuca E,
Akcakanat A
, Scott SM, Arango NP, Zheng X, Chen K,
Tapia C
, Tarco E,
Eterovic AK
,
Black DM
,
Litton JK
, Yap TA, Tripathy D,
Mills GB
,
Meric-Bernstam F
. A Population of Heterogeneous Breast Cancer Patient-Derived Xenografts Demonstrate Broad Activity of PARP Inhibitor in BRCA1/2 Wild-Type Tumors. Clin Cancer Res. 2017 Nov 01; 23(21):6468-6477.
PMID:
29093017
; PMCID:
PMC5679124
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Daniels M, Wathoo C, Brusco L,
Lu KH
, Shaw K, Dumbrava EEI,
Arun B
,
Strong L
,
Litton JK
, Eterovic K, Aytac U,
Mendelsohn J
,
Mills GB
, Chen K,
Meric-Bernstam F
. Active Disclosure of Secondary Germline Findings to Deceased Research Participants' Personal Representatives: Process and Outcomes. JCO Precis Oncol. 2017; 1.
PMID:
31552380
; PMCID:
PMC6759057
.
Citations:
1
Fields:
Neo
Neoplasms
Colen RR
, Fujii T, Bilen MA, Kotrotsou A, Abrol S,
Hess KR
,
Hajjar J
,
Suarez-Almazor ME
, Alshawa A,
Hong DS
, Giniebra-Camejo D, Stephen B,
Subbiah V
,
Sheshadri A
,
Mendoza T
,
Fu S
,
Sharma P
,
Meric-Bernstam F
,
Naing A
. Radiomics to predict immunotherapy-induced pneumonitis: proof of concept. Invest New Drugs. 2018 08; 36(4):601-607.
PMID:
29075985
; PMCID:
PMC5924418
.
Citations:
40
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
Kato S, Jardim DL,
Johnson FM
,
Subbiah V
,
Piha-Paul S
,
Tsimberidou AM
, Falchook GS,
Karp D
, Zinner R, Wheler J,
Janku F
,
Fu S
, Lim J, Bean S, Nguyen L, Urban S, Browne E,
Meric-Bernstam F
,
Hong DS
. Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer. Invest New Drugs. 2018 06; 36(3):416-423.
PMID:
29047029
; PMCID:
PMC5908757
.
Citations:
10
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Huang HJ,
Hong DS
,
Tsimberidou AM
,
Fu S
,
Piha-Paul SA
,
Subbiah V
,
Karp DD
,
Naing A
, Krug A, Enderle D, Priewasser T, Noerholm M, Eitan E, Coticchia C, Stoll G, Jordan LM,
Eng C
,
Kopetz ES
, Skog J,
Meric-Bernstam F
,
Janku F
, M?hrmann L. Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers. Clin Cancer Res. 2018 01 01; 24(1):181-188.
PMID:
29051321
; PMCID:
PMC5754253
.
Citations:
63
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Woo SU, Sangai T,
Akcakanat A
, Chen H, Wei C,
Meric-Bernstam F
. Vertical inhibition of the PI3K/Akt/mTOR pathway is synergistic in breast cancer. Oncogenesis. 2017 Oct 09; 6(10):e385.
PMID:
28991258
; PMCID:
PMC5668884
.
Citations:
29
Sen S,
Meric-Bernstam F
,
Hong DS
,
Hess KR
,
Subbiah V
. Co-occurring Genomic Alterations and Association With Progression-Free Survival in BRAFV600-Mutated Nonmelanoma Tumors. J Natl Cancer Inst. 2017 10 01; 109(10).
PMID:
29117359
; PMCID:
PMC6059192
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Johnson A, Khotskaya YB, Brusco L, Zeng J, Holla V, Bailey AM, Litzenburger BC, Sanchez N, Shufean MA,
Piha-Paul S
,
Subbiah V
,
Hong D
,
Routbort M
,
Broaddus R
, Mills Shaw KR,
Mills GB
,
Mendelsohn J
,
Meric-Bernstam F
. Clinical Use of Precision Oncology Decision Support. JCO Precis Oncol. 2017; 2017.
PMID:
30320296
; PMCID:
PMC6179148
.
Citations:
12
Fields:
Neo
Neoplasms
Tsimberidou AM
,
Hong DS
, Ye Y, Cartwright C, Wheler JJ, Falchook GS,
Naing A
,
Fu S
,
Piha-Paul S
,
Janku F
,
Meric-Bernstam F
,
Hwu P
,
Kee B
,
Kies MS
,
Broaddus R
,
Mendelsohn J
,
Hess KR
, Kurzrock R. Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT): An MD Anderson Precision Medicine Study. JCO Precis Oncol. 2017; 2017.
PMID:
29082359
; PMCID:
PMC5659750
.
Citations:
62
Fields:
Neo
Neoplasms
Arango NP, Yuca E,
Zhao M
, Evans KW, Scott S, Kim C, Gonzalez-Angulo AM,
Janku F
,
Ueno NT
, Tripathy D,
Akcakanat A
,
Naing A
,
Meric-Bernstam F
. Selinexor (KPT-330) demonstrates anti-tumor efficacy in preclinical models of triple-negative breast cancer. Breast Cancer Res. 2017 Aug 15; 19(1):93.
PMID:
28810913
; PMCID:
PMC5557476
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Gao R, Kim C, Sei E, Foukakis T, Crosetto N, Chan LK, Srinivasan M, Zhang H,
Meric-Bernstam F
,
Navin N
. Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer. Nat Commun. 2017 08 09; 8(1):228.
PMID:
28794488
; PMCID:
PMC5550415
.
Citations:
56
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Goldstein JB, Tang C,
Hess KR
,
Hong D
,
Subbiah V
,
Janku F
,
Fu S
,
Karp DD
,
Naing A
,
Tsimberidou AM
, Wheler J, Zinner R,
Javle M
,
Varadhachary GR
,
Wolff RA
,
Fogelman DR
,
Meric-Bernstam F
,
Piha-Paul SA
. Outcomes of phase I clinical trials for patients with advanced pancreatic cancer: update of the MD Anderson Cancer Center experience. Oncotarget. 2017 Oct 20; 8(50):87163-87173.
PMID:
29152071
; PMCID:
PMC5675623
.
Citations:
Fields:
Neo
Neoplasms
Arango NP, Brusco L, Mills Shaw KR, Chen K,
Eterovic AK
, Holla V, Johnson A, Litzenburger B, Khotskaya YB, Sanchez N, Bailey A, Zheng X, Horombe C, Kopetz S, Farhangfar CJ,
Routbort M
,
Broaddus R
,
Bernstam EV
,
Mendelsohn J
,
Mills GB
,
Meric-Bernstam F
. A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory. Oncotarget. 2017 Jun 27; 8(26):41806-41814.
PMID:
28415679
; PMCID:
PMC5522029
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Groisberg R,
Hong DS
, Holla V,
Janku F
,
Piha-Paul S
,
Ravi V
, Benjamin R, Kumar Patel S,
Somaiah N
,
Conley A
, Ali SM, Schrock AB, Ross JS, Stephens PJ, Miller VA, Sen S,
Herzog C
,
Meric-Bernstam F
,
Subbiah V
. Clinical genomic profiling to identify actionable alterations for investigational therapies in patients with diverse sarcomas. Oncotarget. 2017 Jun 13; 8(24):39254-39267.
PMID:
28424409
; PMCID:
PMC5503611
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Janku F
, Zhang S, Waters J, Liu L, Huang HJ,
Subbiah V
,
Hong DS
,
Karp DD
,
Fu S
, Cai X, Ramzanali NM, Madwani K, Cabrilo G, Andrews DL, Zhao Y,
Javle M
,
Kopetz ES
,
Luthra R
, Kim HJ, Gnerre S, Satya RV, Chuang HY, Kruglyak KM, Toung J, Zhao C, Shen R,
Heymach JV
,
Meric-Bernstam F
,
Mills GB
, Fan JB, Salathia NS. Development and Validation of an Ultradeep Next-Generation Sequencing Assay for Testing of Plasma Cell-Free DNA from Patients with Advanced Cancer. Clin Cancer Res. 2017 Sep 15; 23(18):5648-5656.
PMID:
28536309
; PMCID:
PMC5600825
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Wang Z,
Piha-Paul S
,
Janku F
,
Subbiah V
, Shi N, Gong J, Wathoo C, Shaw K, Hess K,
Broaddus R
,
Naing A
,
Hong D
,
Tsimberidou AM
,
Karp D
,
Yao J
,
Meric-Bernstam F
,
Fu S
. Antiangiogenesis and gene aberration-related therapy may improve overall survival in patients with concurrent KRAS and TP53 hotspot mutant cancer. Oncotarget. 2017 May 16; 8(20):33796-33806.
PMID:
28430579
; PMCID:
PMC5464912
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Lesurf R, Griffith OL, Griffith M, Hundal J, Trani L, Watson MA, Aft R, Ellis MJ, Ota D, Suman VJ,
Meric-Bernstam F
, Leitch AM, Boughey JC, Unzeitig G,
Buzdar AU
, Hunt KK, Mardis ER. Genomic characterization of HER2-positive breast cancer and response to neoadjuvant trastuzumab and chemotherapy-results from the ACOSOG Z1041 (Alliance) trial. Ann Oncol. 2017 05 01; 28(5):1070-1077.
PMID:
28453704
; PMCID:
PMC5790063
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Subbiah V
, Khawaja MR,
Hong DS
,
Amini B
, Yungfang J, Liu H, Johnson A, Schrock AB, Ali SM, Sun JX, Fabrizio D,
Piha-Paul S
,
Fu S
,
Tsimberidou AM
,
Naing A
,
Janku F
,
Karp DD
,
Overman M
,
Eng C
, Kopetz S,
Meric-Bernstam F
, Falchook GS. First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients. JCI Insight. 2017 Apr 20; 2(8).
PMID:
28422758
; PMCID:
PMC5396533
.
Citations:
13
Fields:
Med
Medicine (General)
Reilley MJ, Bailey A,
Subbiah V
,
Janku F
,
Naing A
, Falchook G,
Karp D
,
Piha-Paul S
,
Tsimberidou A
,
Fu S
, Lim J, Bean S, Bass A, Montez S, Vence L,
Sharma P
,
Allison J
,
Meric-Bernstam F
,
Hong DS
. Phase I clinical trial of combination imatinib and ipilimumab in patients with advanced malignancies. J Immunother Cancer. 2017; 5:35.
PMID:
28428884
; PMCID:
PMC5394629
.
Citations:
24
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Hess K, Zer A,
Meric-Bernstam F
, Siu LL, Razak ARA,
Hong DS
, Bugano DDG, Jardim DLF. Use of Expansion Cohorts in Phase I Trials and Probability of Success in Phase II for 381 Anticancer Drugs. Clin Cancer Res. 2017 Aug 01; 23(15):4020-4026.
PMID:
28377482
; PMCID:
PMC5540786
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Subbiah V
, Meyer C, Zinner R,
Meric-Bernstam F
, Zahurak ML, O'Connor A, Roszik J, Shaw K,
Ludwig JA
, Kurzrock R, Azad NA. Phase Ib/II Study of the Safety and Efficacy of Combination Therapy with Multikinase VEGF Inhibitor Pazopanib and MEK Inhibitor Trametinib In Advanced Soft Tissue Sarcoma. Clin Cancer Res. 2017 08 01; 23(15):4027-4034.
PMID:
28377484
; PMCID:
PMC5754188
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Basho RK,
Gilcrease M
,
Murthy RK
, Helgason T,
Karp DD
,
Meric-Bernstam F
,
Hess KR
, Herbrich SM,
Valero V
,
Albarracin C
,
Litton JK
, Chavez-MacGregor M,
Ibrahim NK
, Murray JL,
Koenig KB
,
Hong D
,
Subbiah V
, Kurzrock R,
Janku F
,
Moulder SL
. Targeting the PI3K/AKT/mTOR Pathway for the Treatment of Mesenchymal Triple-Negative Breast Cancer: Evidence From a Phase 1 Trial of mTOR Inhibition in Combination With Liposomal Doxorubicin and Bevacizumab. JAMA Oncol. 2017 Apr 01; 3(4):509-515.
PMID:
27893038
.
Citations:
64
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Allenson K, Castillo J, San Lucas FA, Scelo G, Kim DU, Bernard V, Davis G, Kumar T, Katz M, Overman MJ, Foretova L, Fabianova E, Holcatova I, Janout V,
Meric-Bernstam F
, Gascoyne P,
Wistuba I
,
Varadhachary G
, Brennan P,
Hanash S
, Li D,
Maitra A
, Alvarez H. High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients. Ann Oncol. 2017 04 01; 28(4):741-747.
PMID:
28104621
; PMCID:
PMC5834026
.
Citations:
149
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Mehrvarz Sarshekeh A, Advani S,
Overman MJ
, Manyam G,
Kee BK
,
Fogelman DR
, Dasari A,
Raghav K
, Vilar E, Manuel S,
Shureiqi I
,
Wolff RA
,
Patel KP
, Luthra R, Shaw K,
Eng C
,
Maru DM
,
Routbort MJ
,
Meric-Bernstam F
, Kopetz S. Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer. PLoS One. 2017; 12(3):e0173345.
PMID:
28267766
; PMCID:
PMC5340382
.
Citations:
40
Fields:
Med
Medicine (General)
Sci
Science
Janku F
, Huang HJ, Fujii T, Shelton DN, Madwani K, Fu S,
Tsimberidou AM
,
Piha-Paul SA
, Wheler JJ, Zinner RG, Naing A, Hong DS,
Karp DD
, Cabrilo G, Kopetz ES, Subbiah V, Luthra R, Kee BK, Eng C, Morris VK, Karlin-Neumann GA,
Meric-Bernstam F
. Multiplex KRASG12/G13 mutation testing of unamplified cell-free DNA from the plasma of patients with advanced cancers using droplet digital polymerase chain reaction. Ann Oncol. 2017 03 01; 28(3):642-650.
PMID:
27993791
; PMCID:
PMC5834133
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Matsuda N, Lim B, Wang Y,
Krishnamurthy S
,
Woodward W
, Alvarez RH,
Lucci A
,
Valero V
, Reuben JM,
Meric-Bernstam F
,
Ueno NT
. Identification of frequent somatic mutations in inflammatory breast cancer. Breast Cancer Res Treat. 2017 Jun; 163(2):263-272.
PMID:
28243898
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Khotskaya YB, Holla VR, Farago AF, Mills Shaw KR,
Meric-Bernstam F
,
Hong DS
. Targeting TRK family proteins in cancer. Pharmacol Ther. 2017 May; 173:58-66.
PMID:
28174090
.
Citations:
77
Fields:
Dru
Drug Therapy
Pha
Pharmacology
The
Therapeutics
Translation:
Humans
Animals
Fujii T, Barzi A, Siravegna G,
Karp DD
,
Piha-Paul SA
,
Subbiah V
,
Tsimberidou AM
, Huang HJ, Di Nicolantonio F, Pingle S, Vibat CRT, Hancock S, Berz D, Melnikova VO, Erlander MG,
Luthra R
,
Kopetz ES
,
Meric-Bernstam F
, Lenz HJ, Bardelli A,
Janku F
, Sartore-Bianchi A, Cassingena A, Veronese S, Siena S. Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers. Clin Cancer Res. 2017 Jul 15; 23(14):3657-3666.
PMID:
28096270
; PMCID:
PMC5511562
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Holla VR, Elamin YY, Bailey AM, Johnson AM, Litzenburger BC, Khotskaya YB, Sanchez NS, Zeng J, Shufean MA, Shaw KR,
Mendelsohn J
,
Mills GB
,
Meric-Bernstam F
,
Simon GR
. ALK: a tyrosine kinase target for cancer therapy. Cold Spring Harb Mol Case Stud. 2017 Jan; 3(1):a001115.
PMID:
28050598
; PMCID:
PMC5171696
.
Citations:
49
Fields:
Gen
Genetics
Kim J, de Sampaio PC, Lundy DM, Peng Q, Evans KW, Sugimoto H, Gagea M, Kienast Y, Eikesdal HP,
Meric-Bernstam F
,
LeBleu VS
, Amaral NSD, Rocha RM, L?nning PE. Heterogeneous perivascular cell coverage affects breast cancer metastasis and response to chemotherapy. JCI Insight. 2016 Dec 22; 1(21):e90733.
PMID:
28018977
; PMCID:
PMC5161212
.
Citations:
10
Fields:
Med
Medicine (General)
Dobrolecki LE, Airhart SD, Alferez DG, Aparicio S, Behbod F, Bentires-Alj M, Bult CJ, Cai S, Clarke RB, Dowst H, Ellis MJ, Gonzalez-Suarez E, Kabos P, Li S, Lindeman GJ, Marangoni E, McCoy A,
Meric-Bernstam F
,
Piwnica-Worms H
, Poupon MF, Reis-Filho J, Sartorius CA, Tu Y, Visvader JE, Welm A, Wicha MS,
Lewis MT
, Brisken C, Iggo RD, Scabia V, Sflomos G, Vaillant F. Patient-derived xenograft (PDX) models in basic and translational breast cancer research. Cancer Metastasis Rev. 2016 12; 35(4):547-573.
PMID:
28025748
; PMCID:
PMC5396460
.
Citations:
96
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Wang Z, Shi N,
Naing A
,
Janku F
,
Subbiah V
,
Araujo DM
,
Patel SR
,
Ludwig JA
,
Ramondetta LM
,
Levenback CF
,
Ramirez PT
,
Piha-Paul SA
,
Hong D
,
Karp DD
,
Tsimberidou AM
,
Meric-Bernstam F
,
Fu S
. Survival of patients with metastatic leiomyosarcoma: the MD Anderson Clinical Center for targeted therapy experience. Cancer Med. 2016 12; 5(12):3437-3444.
PMID:
27882721
; PMCID:
PMC5224847
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Basho RK, de Melo Gagliato D,
Ueno NT
, Wathoo C, Chen H, Shariati M, Wei C, Alvarez RH,
Moulder SL
,
Sahin AA
, Roy-Chowdhuri S, Chavez-MacGregor M,
Litton JK
, Valero V, Luthra R, Zeng J, Shaw KR,
Mendelsohn J
,
Mills GB
, Tripathy D,
Meric-Bernstam F
. Clinical outcomes based on multigene profiling in metastatic breast cancer patients. Oncotarget. 2016 Nov 22; 7(47):76362-76373.
PMID:
27806348
; PMCID:
PMC5363515
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Tang C,
Hess KR
, Sanders D, Davis SE,
Buzdar AU
, Kurzrock R, Lee JJ,
Meric-Bernstam F
,
Hong DS
. Modifying the Clinical Research Infrastructure at a Dedicated Clinical Trials Unit: Assessment of Trial Development, Activation, and Participant Accrual. Clin Cancer Res. 2017 Mar 15; 23(6):1407-1413.
PMID:
27852698
; PMCID:
PMC5872813
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Kinahan H, Maiti A, Hess K, Dempsey J, Beatty L, Baldwin S,
Hong DS
,
Naing A
,
Fu S
,
Tsimberidou AM
,
Piha-Paul S
,
Janku F
,
Karp D
, Reddy S,
Yennu S
,
Epner D
,
Bruera E
,
Meric-Bernstam F
, Falchook G,
Subbiah V
. Post-Discharge Survival Outcomes of Patients with Advanced Cancer from the University of Texas MD Anderson Cancer Center Investigational Cancer Therapeutics (Phase I Trials) Inpatient Unit. Oncology. 2017; 92(1):14-20.
PMID:
27802448
; PMCID:
PMC5308283
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Shen C
,
Meric-Bernstam F
,
Su X
,
Mendelsohn J
,
Giordano S
. Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel. Oncotarget. 2016 Nov 01; 7(44):71686-71695.
PMID:
27634896
; PMCID:
PMC5342111
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Roszik J
, Haydu LE,
Hess KR
, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC,
Baladandayuthapani V
,
Tetzlaff MT
,
Wargo JA
, Chen K,
Haymaker CL
, Chen JQ,
Meric-Bernstam F
,
Eterovic AK
, Shaw KR,
Mills GB
,
Gershenwald JE
, Radvanyi LG,
Hwu P
, Futreal PA,
Gibbons DL
,
Lazar AJ
,
Bernatchez C
,
Davies MA
,
Woodman SE
, Forget MA. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Med. 2016 10 25; 14(1):168.
PMID:
27776519
; PMCID:
PMC5078889
.
Citations:
64
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Subbiah V
, Holmes O, Gowen K, Spritz D,
Amini B
, Wang WL, Schrock AB,
Meric-Bernstam F
, Zinner R,
Piha-Paul S
,
Zarzour M
, Elvin JA, Erlich RL, Stockman DL, Vergilio JA, Suh JH, Stephens PJ, Miller V, Ross JS, Ali SM. Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion. Oncology. 2016; 91(6):348-353.
PMID:
27764830
; PMCID:
PMC5130597
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Subbiah V
,
Hess KR
, Khawaja MR, Wagner MJ, Tang C,
Naing A
,
Fu S
,
Janku F
,
Piha-Paul S
,
Tsimberidou AM
,
Herzog CE
,
Ludwig JA
,
Patel S
,
Ravi V
, Benjamin RS,
Meric-Bernstam F
,
Hong DS
. Evaluation of Novel Targeted Therapies in Aggressive Biology Sarcoma Patients after progression from US FDA approved Therapies. Sci Rep. 2016 10 17; 6:35448.
PMID:
27748430
; PMCID:
PMC5066200
.
Citations:
7
Fields:
Sci
Science
Translation:
Humans
Hong DS
,
Morris VK
, El Osta B, Sorokin AV,
Janku F
,
Fu S
,
Overman MJ
,
Piha-Paul S
,
Subbiah V
,
Kee B
,
Tsimberidou AM
,
Fogelman D
, Bellido J,
Shureiqi I
, Huang H, Atkins J, Tarcic G, Sommer N, Lanman R,
Meric-Bernstam F
, Kopetz S. Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation. Cancer Discov. 2016 12; 6(12):1352-1365.
PMID:
27729313
; PMCID:
PMC5562357
.
Citations:
100
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
CT
Clinical Trials
Park H, Garrido-Laguna I,
Naing A
,
Fu S
, Falchook GS,
Piha-Paul SA
, Wheler JJ,
Hong DS
,
Tsimberidou AM
,
Subbiah V
, Zinner RG,
Kaseb AO
,
Patel S
,
Fanale MA
, Velez-Bravo VM,
Meric-Bernstam F
, Kurzrock R,
Janku F
. Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy. Oncotarget. 2016 Oct 11; 7(41):67521-67531.
PMID:
27589687
; PMCID:
PMC5341894
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
FitzSullivan E
, Bassett RL,
Kuerer HM
,
Mittendorf EA
, Yi M,
Hunt KK
,
Babiera GV
,
Caudle AS
,
Black DM
,
Bedrosian I
,
Reyna C
,
Teshome M
,
Meric-Bernstam F
,
Hwang R
. Outcomes of Sentinel Lymph Node-Positive Breast Cancer Patients Treated with Mastectomy Without Axillary Therapy. Ann Surg Oncol. 2017 Mar; 24(3):652-659.
PMID:
27822630
; PMCID:
PMC5977973
.
Citations:
4
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Bupathi M,
Hajjar J
, Bean S,
Fu S
,
Hong D
,
Karp D
, Stephen B, Hess K,
Meric-Bernstam F
,
Naing A
. Incidence of infusion reactions to anti-neoplastic agents in early phase clinical trials: The MD Anderson Cancer Center experience. Invest New Drugs. 2017 02; 35(1):59-67.
PMID:
27687047
; PMCID:
PMC5896759
.
Citations:
1
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
Livingston JA,
Hess KR
,
Naing A
,
Hong DS
,
Patel S
, Benjamin RS,
Ludwig JA
,
Conley A
,
Herzog CE
, Anderson P,
Meric-Bernstam F
, Kurzrock R,
Subbiah V
. Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials. Oncotarget. 2016 Sep 27; 7(39):64421-64430.
PMID:
27486883
; PMCID:
PMC5325454
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Javle M
, Bekaii-Saab T, Jain A, Wang Y, Kelley RK, Wang K, Kang HC, Catenacci D, Ali S,
Krishnan S
, Ahn D, Bocobo AG,
Zuo M
,
Kaseb A
, Miller V, Stephens PJ,
Meric-Bernstam F
,
Shroff R
, Ross J. Biliary cancer: Utility of next-generation sequencing for clinical management. Cancer. 2016 Dec 15; 122(24):3838-3847.
PMID:
27622582
.
Citations:
108
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Raghav K
,
Morris V
, Tang C, Morelli P,
Amin HM
, Chen K, Manyam GC,
Broom B
,
Overman MJ
, Shaw K,
Meric-Bernstam F
,
Maru D
,
Menter D
,
Ellis LM
,
Eng C
,
Hong D
, Kopetz S. MET amplification in metastatic colorectal cancer: an acquired response to EGFR inhibition, not a de novo phenomenon. Oncotarget. 2016 08 23; 7(34):54627-54631.
PMID:
27421137
; PMCID:
PMC5342368
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Gao R, Davis A, McDonald TO, Sei E, Shi X, Wang Y, Tsai PC, Casasent A, Waters J, Zhang H,
Meric-Bernstam F
, Michor F,
Navin NE
. Punctuated copy number evolution and clonal stasis in triple-negative breast cancer. Nat Genet. 2016 10; 48(10):1119-30.
PMID:
27526321
; PMCID:
PMC5042845
.
Citations:
191
Fields:
Gen
Genetics
Translation:
Humans
Cells
Stauder MC
,
Caudle AS
, Allen PK,
Shaitelman SF
,
Smith BD
,
Hoffman KE
,
Buchholz TA
, Chavez-Macgregor M,
Hunt KK
,
Meric-Bernstam F
,
Woodward WA
. Outcomes of Post Mastectomy Radiation Therapy in Patients Receiving Axillary Lymph Node Dissection After Positive Sentinel Lymph Node Biopsy. Int J Radiat Oncol Biol Phys. 2016 11 01; 96(3):637-44.
PMID:
27681760
.
Citations:
1
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Wheler JJ, Atkins JT,
Janku F
,
Moulder SL
, Stephens PJ, Yelensky R, Valero V, Miller V, Kurzrock R,
Meric-Bernstam F
. Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors. Oncoscience. 2016; 3(5-6):164-72.
PMID:
27489863
; PMCID:
PMC4965259
.
Citations:
17
Chen T, Wang Z, Zhou W, Chong Z,
Meric-Bernstam F
,
Mills GB
, Chen K. Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types. BMC Genomics. 2016 06 23; 17 Suppl 2:394.
PMID:
27356755
; PMCID:
PMC4928158
.
Citations:
18
Fields:
Gen
Genetics
Translation:
Humans
Cells
Curigliano G,
Meric-Bernstam F
, Conte P, Lolkema MP, Beck JT, Bardia A, Dhuria S, Tang Z, Solovieff N, Miller M, Di Tomaso E, Hurvitz SA, G?mez Pardo P, Mart?nez Garc?a M, Penault-Llorca F. Ribociclib plus letrozole in early breast cancer: A presurgical, window-of-opportunity study. Breast. 2016 Aug; 28:191-8.
PMID:
27336726
.
Citations:
44
Fields:
End
Endocrinology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Bilen MA, Patel A,
Hess KR
, Munoz J,
Busaidy NL
, Wheler JJ,
Janku F
, Falchook GS,
Hong DS
,
Meric-Bernstam F
,
Habra MA
,
Naing A
. Association between new-onset hypothyroidism and clinical response in patients treated with tyrosine kinase inhibitor therapy in phase I clinical trials. Cancer Chemother Pharmacol. 2016 07; 78(1):167-71.
PMID:
27286994
.
Citations:
3
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Hou MM, Wang Z,
Janku F
,
Piha-Paul S
,
Naing A
,
Hong D
,
Westin S
,
Coleman RL
,
Sood AK
,
Tsimberidou AM
,
Subbiah V
, Wheler J, Zinner R,
Lu K
,
Meric-Bernstam F
,
Fu S
. Continuous anti-angiogenic therapy after tumor progression in patients with recurrent high-grade epithelial ovarian cancer: phase I trial experience. Oncotarget. 2016 Jun 07; 7(23):35132-43.
PMID:
27147567
; PMCID:
PMC5085215
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Janku F
, Huang HJ, Claes B, Falchook GS,
Fu S
,
Hong D
, Ramzanali NM, Nitti G, Cabrilo G,
Tsimberidou AM
,
Naing A
,
Piha-Paul SA
, Wheler JJ,
Karp DD
, Holley VR, Zinner RG,
Subbiah V
,
Luthra R
, Kopetz S,
Overman MJ
,
Kee BK
,
Patel S
, Devogelaere B, Sablon E, Maertens G,
Mills GB
, Kurzrock R,
Meric-Bernstam F
. BRAF Mutation Testing in Cell-Free DNA from the Plasma of Patients with Advanced Cancers Using a Rapid, Automated Molecular Diagnostics System. Mol Cancer Ther. 2016 06; 15(6):1397-404.
PMID:
27207774
.
Citations:
43
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
Dennison JB, Shahmoradgoli M, Liu W, Ju Z,
Meric-Bernstam F
, Perou CM,
Sahin AA
, Welm A, Oesterreich S, Sikora MJ, Brown RE,
Mills GB
. High Intratumoral Stromal Content Defines Reactive Breast Cancer as a Low-risk Breast Cancer Subtype. Clin Cancer Res. 2016 Oct 15; 22(20):5068-5078.
PMID:
27172895
; PMCID:
PMC5103285
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Fathiamini S, Johnson AM, Zeng J, Araya A, Holla V, Bailey AM, Litzenburger BC, Sanchez NS, Khotskaya Y, Xu H,
Meric-Bernstam F
,
Bernstam EV
, Cohen T. Automated identification of molecular effects of drugs (AIMED). J Am Med Inform Assoc. 2016 07; 23(4):758-65.
PMID:
27107438
; PMCID:
PMC4926748
.
Citations:
10
Fields:
Med
Medical Informatics
Translation:
Humans
Xu J, Lee HJ, Zeng J, Wu Y, Zhang Y, Huang LC, Johnson A, Holla V, Bailey AM, Cohen T,
Meric-Bernstam F
,
Bernstam EV
, Xu H. Extracting genetic alteration information for personalized cancer therapy from ClinicalTrials.gov. J Am Med Inform Assoc. 2016 07; 23(4):750-7.
PMID:
27013523
; PMCID:
PMC4926744
.
Citations:
15
Fields:
Med
Medical Informatics
Translation:
Humans
Khawaja MR, Nick AM, Madhusudanannair V,
Fu S
,
Hong D
, McQuinn LM,
Ng CS
,
Piha-Paul SA
,
Janku F
,
Subbiah V
,
Tsimberidou A
,
Karp D
,
Meric-Bernstam F
,
Lu KH
,
Naing A
. Phase I dose escalation study of temsirolimus in combination with metformin in patients with advanced/refractory cancers. Cancer Chemother Pharmacol. 2016 05; 77(5):973-7.
PMID:
27014780
; PMCID:
PMC5978416
.
Citations:
19
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
McAuliffe PF, Evans KW,
Akcakanat A
, Chen K, Zheng X, Zhao H,
Eterovic AK
, Sangai T, Holder AM, Sharma C, Chen H, Do KA, Tarco E, Gagea M,
Naff KA
, Sahin A,
Multani AS
,
Black DM
, Mittendorf EA,
Bedrosian I
,
Mills GB
, Gonzalez-Angulo AM,
Meric-Bernstam F
. Correction: Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes. PLoS One. 2016; 11(3):e0151121.
PMID:
26953790
; PMCID:
PMC4782992
.
Citations:
2
Fields:
Med
Medicine (General)
Sci
Science
Subbiah V
,
Hong DS
,
Meric-Bernstam F
. Clinical activity of ceritinib in ROS1-rearranged non-small cell lung cancer: Bench to bedside report. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):E1419-20.
PMID:
26917690
; PMCID:
PMC4801313
.
Citations:
14
Fields:
Sci
Science
Translation:
Humans
Overman MJ
, Morris V, Kee B, Fogelman D, Xiao L, Eng C, Dasari A, Shroff R, Mazard T, Shaw K, Vilar E, Raghav K,
Shureiqi I
, Liang L,
Mills GB
,
Wolff RA
, Hamilton S,
Meric-Bernstam F
, Abbruzzese J, Morris J,
Maru D
, Kopetz S. Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials. Ann Oncol. 2016 06; 27(6):1068-1074.
PMID:
27045102
; PMCID:
PMC6276928
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Meric-Bernstam F
, Brusco L, Daniels M, Wathoo C, Bailey AM, Strong L, Shaw K, Lu K, Qi Y, Zhao H, Lara-Guerra H, Litton J,
Arun B
, Eterovic AK, Aytac U, Routbort M, Subbiah V,
Janku F
, Davies MA, Kopetz S, Mendelsohn J,
Mills GB
, Chen K. Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol. Ann Oncol. 2016 05; 27(5):795-800.
PMID:
26787237
; PMCID:
PMC4843184
.
Citations:
57
Fields:
Neo
Neoplasms
Translation:
Humans
Rogith D, Yusuf RA, Hovick SR, Fellman BM,
Peterson SK
, Burton-Chase AM, Li Y,
Bernstam EV
,
Meric-Bernstam F
. Patient knowledge and information-seeking about personalized cancer therapy. Int J Med Inform. 2016 Apr; 88:52-7.
PMID:
26878762
; PMCID:
PMC4789765
.
Citations:
10
Fields:
Med
Medical Informatics
Translation:
Humans
Meric-Bernstam F
, Shaw K,
Mendelsohn J
,
Mills GB
. Reply to M.P. Decatris et al. J Clin Oncol. 2016 Mar 10; 34(8):886.
PMID:
26755522
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Fu S
, Shi N, Wheler J,
Naing A
,
Janku F
,
Piha-Paul S
, Gong J,
Hong D
,
Tsimberidou A
, Zinner R,
Subbiah V
, Hou MM,
Ramirez P
,
Ramondetta L
,
Lu K
,
Meric-Bernstam F
. Characteristics and outcomes for patients with advanced vaginal or vulvar cancer referred to a phase I clinical trials program: the MD Anderson cancer center experience. Gynecol Oncol Res Pract. 2015; 2:10.
PMID:
27231570
; PMCID:
PMC4880813
.
Citations:
5
Mo W, Liu Q, Lin CC, Dai H, Peng Y, Liang Y, Peng G,
Meric-Bernstam F
,
Mills GB
, Li K,
Lin SY
. mTOR Inhibitors Suppress Homologous Recombination Repair and Synergize with PARP Inhibitors via Regulating SUV39H1 in BRCA-Proficient Triple-Negative Breast Cancer. Clin Cancer Res. 2016 Apr 01; 22(7):1699-712.
PMID:
26546619
; PMCID:
PMC4858320
.
Citations:
42
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Roy-Chowdhuri S, de Melo Gagliato D,
Routbort MJ
,
Patel KP
,
Singh RR
,
Broaddus R
,
Lazar AJ
,
Sahin A
, Alvarez RH,
Moulder S
, Wheler JJ,
Janku F
, Gonzalez-Angulo AM, Chavez-MacGregor M, Valero V,
Ueno NT
,
Mills G
,
Mendelsohn J
, Yao H, Aldape K,
Luthra R
,
Meric-Bernstam F
. Multigene clinical mutational profiling of breast carcinoma using next-generation sequencing. Am J Clin Pathol. 2015 Nov; 144(5):713-21.
PMID:
26486734
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
Zhou W, Chen T, Chong Z, Rohrdanz MA, Melott JM, Wakefield C, Zeng J,
Weinstein JN
,
Meric-Bernstam F
,
Mills GB
, Chen K. TransVar: a multilevel variant annotator for precision genomics. Nat Methods. 2015 Nov; 12(11):1002-3.
PMID:
26513549
; PMCID:
PMC4772859
.
Citations:
31
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Liu X, George GC,
Tsimberidou AM
, Naing A, Wheler JJ, Kopetz S, Fu S,
Piha-Paul SA
, Eng C, Falchook GS,
Janku F
, Garrett C,
Karp D
, Kurzrock R, Zinner R, Raghav K, Subbiah V, Hess K,
Meric-Bernstam F
, Hong DS, Overman MJ. Retreatment with anti-EGFR based therapies in metastatic colorectal cancer: impact of intervening time interval and prior anti-EGFR response. BMC Cancer. 2015 Oct 16; 15:713.
PMID:
26474549
; PMCID:
PMC4609167
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Janku F
, Claes B, Huang HJ, Falchook GS, Devogelaere B, Kockx M, Bempt IV, Reijans M,
Naing A
, Fu S,
Piha-Paul SA
,
Hong DS
, Holley VR,
Tsimberidou AM
, Stepanek VM,
Patel SP
, Kopetz ES,
Subbiah V
, Wheler JJ, Zinner RG,
Karp DD
,
Luthra R
, Roy-Chowdhuri S, Sablon E,
Meric-Bernstam F
, Maertens G, Kurzrock R. BRAF mutation testing with a rapid, fully integrated molecular diagnostics system. Oncotarget. 2015 Sep 29; 6(29):26886-94.
PMID:
26330075
; PMCID:
PMC4694960
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Janku F
, Angenendt P,
Tsimberidou AM
, Fu S,
Naing A
, Falchook GS,
Hong DS
, Holley VR, Cabrilo G, Wheler JJ,
Piha-Paul SA
, Zinner RG, Bedikian AY,
Overman MJ
,
Kee BK
, Kim KB, Kopetz ES,
Luthra R
, Diehl F,
Meric-Bernstam F
, Kurzrock R. Erratum: Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies. Oncotarget. 2015 Sep 15; 6(27):24581.
PMID:
26405159
; PMCID:
PMC4695208
.
Citations:
1
Fields:
Neo
Neoplasms
McAuliffe PF, Evans KW,
Akcakanat A
, Chen K, Zheng X, Zhao H,
Eterovic AK
, Sangai T, Holder AM, Sharma C, Chen H,
Do KA
, Tarco E, Gagea M,
Naff KA
,
Sahin A
,
Multani AS
,
Black DM
,
Mittendorf EA
,
Bedrosian I
,
Mills GB
, Gonzalez-Angulo AM,
Meric-Bernstam F
. Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes. PLoS One. 2015; 10(9):e0136851.
PMID:
26325287
; PMCID:
PMC4556673
.
Citations:
32
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Boland GM,
Piha-Paul SA
,
Subbiah V
,
Routbort M
, Herbrich SM,
Baggerly K
,
Patel KP
, Brusco L, Horombe C,
Naing A
, Fu S,
Hong DS
,
Janku F
, Johnson A,
Broaddus R
, Luthra R, Shaw K,
Mendelsohn J
,
Mills GB
,
Meric-Bernstam F
. Clinical next generation sequencing to identify actionable aberrations in a phase I program. Oncotarget. 2015 Aug 21; 6(24):20099-110.
PMID:
26015395
; PMCID:
PMC4652990
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Holder AM,
Akcakanat A
, Adkins F, Evans K, Chen H, Wei C, Milton DR, Li Y,
Do KA
,
Janku F
,
Meric-Bernstam F
. Epithelial to mesenchymal transition is associated with rapamycin resistance. Oncotarget. 2015 Aug 14; 6(23):19500-13.
PMID:
25944619
; PMCID:
PMC4637301
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Bedrosian I
, Xing Y, Abdel Rahman S, Allen L,
Le-Petross H
,
Whitman GJ
,
Meric-Bernstam F
,
Hunt KK
,
Babiera GV
,
Cormier JN
. A Cost Analysis of Preoperative Breast MRI Use for Patients with Invasive Lobular Cancer. Ann Surg Oncol. 2016 Jan; 23(1):23-9.
PMID:
26156655
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Johnson A, Zeng J, Bailey AM, Holla V, Litzenburger B, Lara-Guerra H,
Mills GB
,
Mendelsohn J
, Shaw KR,
Meric-Bernstam F
. The right drugs at the right time for the right patient: the MD Anderson precision oncology decision support platform. Drug Discov Today. 2015 Dec; 20(12):1433-8.
PMID:
26148707
; PMCID:
PMC5648066
.
Citations:
30
Fields:
Dru
Drug Therapy
Pha
Pharmacology
Translation:
Humans
Kato S,
Moulder SL
,
Ueno NT
, Wheler JJ,
Meric-Bernstam F
, Kurzrock R,
Janku F
. Challenges and perspective of drug repurposing strategies in early phase clinical trials. Oncoscience. 2015; 2(6):576-80.
PMID:
26244164
; PMCID:
PMC4506360
.
Citations:
12
Bupathi M,
Kaseb A
,
Meric-Bernstam F
,
Naing A
. Hepatocellular carcinoma: Where there is unmet need. Mol Oncol. 2015 Oct; 9(8):1501-9.
PMID:
26160430
; PMCID:
PMC5528787
.
Citations:
37
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Le Du F,
Eckhardt BL
, Lim B,
Litton JK
,
Moulder S
,
Meric-Bernstam F
, Gonzalez-Angulo AM,
Ueno NT
. Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype? Oncotarget. 2015 May 30; 6(15):12890-908.
PMID:
25973541
; PMCID:
PMC4536987
.
Citations:
45
Fields:
Neo
Neoplasms
Translation:
Humans
Meric-Bernstam F
, Brusco L, Shaw K, Horombe C, Kopetz S,
Davies MA
,
Routbort M
,
Piha-Paul SA
,
Janku F
,
Ueno N
,
Hong D
,
De Groot J
,
Ravi V
, Li Y, Luthra R, Patel K,
Broaddus R
,
Mendelsohn J
,
Mills GB
. Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials. J Clin Oncol. 2015 Sep 01; 33(25):2753-62.
PMID:
26014291
; PMCID:
PMC4550690
.
Citations:
203
Fields:
Neo
Neoplasms
Translation:
Humans
Janku F
, Angenendt P,
Tsimberidou AM
,
Fu S
,
Naing A
, Falchook GS,
Hong DS
, Holley VR, Cabrilo G, Wheler JJ,
Piha-Paul SA
, Zinner RG, Bedikian AY,
Overman MJ
,
Kee BK
, Kim KB,
Kopetz ES
,
Luthra R
, Diehl F,
Meric-Bernstam F
, Kurzrock R. Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies. Oncotarget. 2015 May 20; 6(14):12809-21.
PMID:
25980577
; PMCID:
PMC4494976
.
Citations:
50
Fields:
Neo
Neoplasms
Translation:
Humans
Dasari A, Phan A, Gupta S,
Rashid A
,
Yeung SC
, Hess K, Chen H, Tarco E, Chen H, Wei C, Anh-Do K,
Halperin D
,
Meric-Bernstam F
,
Yao J
. Phase I study of the anti-IGF1R antibody cixutumumab with everolimus and octreotide in advanced well-differentiated neuroendocrine tumors. Endocr Relat Cancer. 2015 Jun; 22(3):431-41.
PMID:
25900182
; PMCID:
PMC4566955
.
Citations:
10
Fields:
End
Endocrinology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Meric-Bernstam F
, Johnson A, Holla V, Bailey AM, Brusco L,
Chen K
,
Routbort M
,
Patel KP
, Zeng J,
Kopetz S
,
Davies MA
,
Piha-Paul SA
,
Hong DS
,
Eterovic AK
,
Tsimberidou AM
,
Broaddus R
,
Bernstam EV
, Shaw KR,
Mendelsohn J
,
Mills GB
. A decision support framework for genomically informed investigational cancer therapy. J Natl Cancer Inst. 2015 Jul; 107(7).
PMID:
25863335
; PMCID:
PMC4651038
.
Citations:
91
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Chen G, Zhao J, Cohen T, Tao C, Sun J, Xu H,
Bernstam EV
, Lawson A, Zeng J, Johnson AM, Holla V, Bailey AM, Lara-Guerra H, Litzenburger B,
Meric-Bernstam F
, Jim Zheng W. Using Ontology Fingerprints to disambiguate gene name entities in the biomedical literature. Database (Oxford). 2015; 2015:bav034.
PMID:
25858285
; PMCID:
PMC4390608
.
Citations:
4
Fields:
Com
Computational Biology
Zhou W, Zhao H, Chong Z, Mark RJ,
Eterovic AK
,
Meric-Bernstam F
, Chen K. ClinSeK: a targeted variant characterization framework for clinical sequencing. Genome Med. 2015; 7(1):34.
PMID:
25918555
; PMCID:
PMC4410453
.
Citations:
6
Fields:
Gen
Genetics
Gonzalez-Angulo AM, Lei X, Alvarez RH, Green MC, Murray JL,
Valero V
,
Koenig KB
,
Ibrahim NK
,
Litton JK
, Nair L,
Krishnamurthy S
, Hortobagyi GN,
Meric-Bernstam F
. Phase II Randomized Study of Ixabepilone Versus Observation in Patients With Significant Residual Disease After Neoadjuvant Systemic Therapy for HER2-Negative Breast Cancer. Clin Breast Cancer. 2015 Oct; 15(5):325-31.
PMID:
25913905
; PMCID:
PMC4568133
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Bayraktar S, Jackson M, Gutierrez-Barrera AM, Liu D,
Meric-Bernstam F
, Brandt A, Woodson A,
Litton J
,
Lu KH
,
Valero V
,
Arun BK
. Genotype-Phenotype Correlations by Ethnicity and Mutation Location in BRCA Mutation Carriers. Breast J. 2015 May-Jun; 21(3):260-7.
PMID:
25789811
; PMCID:
PMC5411012
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Liu S
,
Meric-Bernstam F
, Parinyanitikul N, Wang B,
Eterovic AK
, Zheng X, Gagea M, Chavez-MacGregor M,
Ueno NT
, Lei X, Zhou W, Nair L,
Tripathy D
, Brown PH, Hortobagyi GN,
Chen K
,
Mendelsohn J
,
Mills GB
, Gonzalez-Angulo AM. Functional consequence of the MET-T1010I polymorphism in breast cancer. Oncotarget. 2015 Feb 20; 6(5):2604-14.
PMID:
25605252
; PMCID:
PMC4413604
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Goswami RS,
Patel KP
, Singh RR,
Meric-Bernstam F
,
Kopetz ES
,
Subbiah V
, Alvarez RH,
Davies MA
, Jabbar KJ, Roy-Chowdhuri S,
Lazar AJ
,
Medeiros LJ
,
Broaddus RR
,
Luthra R
,
Routbort MJ
. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clin Cancer Res. 2015 Jun 01; 21(11):2644-51.
PMID:
25695693
; PMCID:
PMC5015593
.
Citations:
41
Fields:
Neo
Neoplasms
Translation:
Humans
Gonzalez-Angulo AM, Krop I,
Akcakanat A
, Chen H, Liu S, Li Y, Culotta KS, Tarco E,
Piha-Paul S
, Moulder-Thompson S, Velez-Bravo V,
Sahin AA
, Doyle LA,
Do KA
, Winer EP,
Mills GB
, Kurzrock R,
Meric-Bernstam F
. SU2C phase Ib study of paclitaxel and MK-2206 in advanced solid tumors and metastatic breast cancer. J Natl Cancer Inst. 2015 Mar; 107(3).
PMID:
25688104
; PMCID:
PMC4342675
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Fu S
, Hou MM, Naing A,
Janku F
,
Hess K
, Zinner R,
Subbiah V
, Hong D, Wheler J,
Piha-Paul S
,
Tsimberidou A
,
Karp D
,
Araujo D
, Kee B,
Hwu P
,
Wolff R
, Kurzrock R,
Meric-Bernstam F
. Phase I study of pazopanib and vorinostat: a therapeutic approach for inhibiting mutant p53-mediated angiogenesis and facilitating mutant p53 degradation. Ann Oncol. 2015 May; 26(5):1012-1018.
PMID:
25669829
; PMCID:
PMC6279067
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Akbani R
, Ng PK, Werner HM, Shahmoradgoli M, Zhang F, Ju Z, Liu W, Yang JY, Yoshihara K, Li J, Ling S, Seviour EG,
Ram PT
, Minna JD, Diao L, Tong P,
Heymach JV
, Hill SM, Dondelinger F,
Byers LA
,
Meric-Bernstam F
,
Weinstein JN
,
Broom BM
, Verhaak RG, Liang H, Mukherjee S, Lu Y,
Mills GB
, St?dler N. Corrigendum: A pan-cancer proteomic perspective on The Cancer Genome Atlas. Nat Commun. 2015 Jan 28; 6:4852.
PMID:
25629879
.
Citations:
4
Fields:
Bio
Biology
Sci
Science
Malhotra A, Wang Y, Waters J, Chen K,
Meric-Bernstam F
, Hall IM,
Navin NE
. Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations. Genome Med. 2015; 7(1):6.
PMID:
25729435
; PMCID:
PMC4343275
.
Citations:
5
Fields:
Gen
Genetics
Chen K
,
Meric-Bernstam F
, Zhao H, Zhang Q, Ezzeddine N, Tang LY, Qi Y, Mao Y, Chen T, Chong Z, Zhou W, Zheng X, Johnson A, Aldape KD,
Routbort MJ
,
Luthra R
,
Kopetz S
,
Davies MA
,
de Groot J
,
Moulder S
, Vinod R, Farhangfar CJ, Shaw KM,
Mendelsohn J
,
Mills GB
,
Eterovic AK
. Clinical actionability enhanced through deep targeted sequencing of solid tumors. Clin Chem. 2015 Mar; 61(3):544-53.
PMID:
25626406
; PMCID:
PMC4511273
.
Citations:
61
Fields:
Che
Chemistry
Translation:
Humans
Grubbs EG
, Ng PK, Bui J,
Busaidy NL
, Chen K, Lee JE, Lu X, Lu H,
Meric-Bernstam F
,
Mills GB
, Palmer G,
Perrier ND
, Scott KL, Shaw KR,
Waguespack SG
,
Williams MD
, Yelensky R,
Cote GJ
. RET fusion as a novel driver of medullary thyroid carcinoma. J Clin Endocrinol Metab. 2015 Mar; 100(3):788-93.
PMID:
25546157
; PMCID:
PMC4333032
.
Citations:
34
Fields:
End
Endocrinology
Met
Metabolism
Translation:
Humans
Churi CR,
Shroff R
, Wang Y,
Rashid A
, Kang HC, Weatherly J, Zuo M, Zinner R,
Hong D
,
Meric-Bernstam F
,
Janku F
, Crane CH, Mishra L, Vauthey JN,
Wolff RA
,
Mills G
,
Javle M
. Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. PLoS One. 2014; 9(12):e115383.
PMID:
25536104
; PMCID:
PMC4275227
.
Citations:
170
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Chen K,
Meric-Bernstam F
. Whole Genome Sequencing in Cancer Clinics. EBioMedicine. 2015 Jan; 2(1):15-6.
PMID:
26137530
; PMCID:
PMC4484824
.
Citations:
1
Fields:
Gen
Genetics
Med
Medicine (General)
Translation:
Humans
Su X
, Chen Y, Zhang J, Yao H,
Valero V
,
Weinstein JN
,
Meric-Bernstam F
, Esteva FJ, Malouf GG, Spano JP, Khayat D. Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes. Oncotarget. 2014 Oct 30; 5(20):9864-76.
PMID:
25296969
; PMCID:
PMC4259443
.
Citations:
106
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jardim DL, Tang C, Gagliato Dde M, Falchook GS, Hess K,
Janku F
,
Fu S
, Wheler JJ, Zinner RG,
Naing A
,
Tsimberidou AM
, Holla V, Li MM, Roy-Chowdhuri S,
Luthra R
, Salgia R, Kurzrock R,
Meric-Bernstam F
,
Hong DS
. Analysis of 1,115 patients tested for MET amplification and therapy response in the MD Anderson Phase I Clinic. Clin Cancer Res. 2014 Dec 15; 20(24):6336-45.
PMID:
25326232
.
Citations:
41
Fields:
Neo
Neoplasms
Translation:
Humans
Hyman DM, Diamond EL, Vibat CR, Hassaine L, Poole JC, Patel M, Holley VR, Cabrilo G, Lu TT, Arcila ME, Chung YR, Rampal R, Lacouture ME, Rosen N,
Meric-Bernstam F
, Kurzrock R, Erlander MG,
Janku F
, Abdel-Wahab O, Baselga J. Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders. Cancer Discov. 2015 Jan; 5(1):64-71.
PMID:
25324352
; PMCID:
PMC5705028
.
Citations:
51
Fields:
Neo
Neoplasms
Translation:
Humans
Liu S
, Meng X, Chen H, Liu W, Miller T, Murph M,
Lu Y
, Zhang F, Gagea M, Arteaga CL,
Mills GB
,
Meric-Bernstam F
, Gonz?lez-Angulo AM. Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer. Oncotarget. 2014 Oct 15; 5(19):9049-64.
PMID:
24979294
; PMCID:
PMC4253418
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Parinyanitikul N, Lei X, Chavez-MacGregor M,
Liu S
,
Mittendorf EA
,
Litton JK
,
Woodward W
, Zhang AH, Hortobagyi GN, Valero V,
Meric-Bernstam F
, Gonzalez-Angulo AM. Receptor status change from primary to residual breast cancer after neoadjuvant chemotherapy and analysis of survival outcomes. Clin Breast Cancer. 2015 Apr; 15(2):153-60.
PMID:
25454687
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Hassan B,
Akcakanat A
, Sangai T, Evans KW, Adkins F,
Eterovic AK
, Zhao H, Chen K, Chen H,
Do KA
, Xie SM, Holder AM,
Naing A
,
Mills GB
,
Meric-Bernstam F
. Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors. Oncotarget. 2014 Sep 30; 5(18):8544-57.
PMID:
25261369
; PMCID:
PMC4226703
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ganesan P,
Moulder S
,
Lee JJ
,
Janku F
,
Valero V
, Zinner RG,
Naing A
,
Fu S
,
Tsimberidou AM
,
Hong D
, Stephen B, Stephens P, Yelensky R,
Meric-Bernstam F
, Kurzrock R, Wheler JJ. Triple-negative breast cancer patients treated at MD Anderson Cancer Center in phase I trials: improved outcomes with combination chemotherapy and targeted agents. Mol Cancer Ther. 2014 Dec; 13(12):3175-84.
PMID:
25253784
; PMCID:
PMC4258414
.
Citations:
16
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
Yusuf RA, Rogith D, Hovick SR,
Peterson SK
, Burton-Chase AM, Fellman BM,
Li Y
, McKinney C,
Bernstam EV
,
Meric-Bernstam F
. Attitudes toward molecular testing for personalized cancer therapy. Cancer. 2015 Jan 15; 121(2):243-50.
PMID:
25209923
; PMCID:
PMC4293219
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Siroy AE, Boland GM, Roszik J, Frankian S, Malke J, Haydu L,
Prieto VG
,
Tetzlaff M
,
Ivan D
, Wang WL, Torres-Cabala C,
Curry J
, Roy-Chowdhuri S,
Broaddus R
,
Rashid A
, Stewart J,
Gershenwald JE
,
Amaria RN
,
Patel SP
, Papadopoulos NE, Bedikian A,
Hwu WJ
,
Hwu P
,
Diab A
,
Woodman SE
, Aldape KD,
Luthra R
,
Patel KP
, Shaw KR,
Mills GB
,
Mendelsohn J
,
Meric-Bernstam F
, Kim KB,
Routbort MJ
,
Lazar AJ
,
Davies MA
, Milton DR. Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma. J Invest Dermatol. 2015 Feb; 135(2):508-515.
PMID:
25148578
; PMCID:
PMC4289407
.
Citations:
56
Fields:
Der
Dermatology
Translation:
Humans
Subbiah V
,
Meric-Bernstam F
,
Mills GB
, Shaw KR, Bailey AM, Rao P, Ward JF, Pagliaro LC. Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent?) a VEGFR2/PDGFR?/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial. J Hematol Oncol. 2014 Aug 01; 7:52.
PMID:
25085632
; PMCID:
PMC4237879
.
Citations:
15
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Wang Y, Waters J, Leung ML, Unruh A, Roh W, Shi X,
Chen K
,
Scheet P
, Vattathil S,
Liang H
,
Multani A
,
Zhang H
, Zhao R, Michor F,
Meric-Bernstam F
,
Navin NE
. Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature. 2014 Aug 14; 512(7513):155-60.
PMID:
25079324
; PMCID:
PMC4158312
.
Citations:
443
Fields:
Sci
Science
Translation:
Humans
Cells
McGuire KP, Hwang ES, Cantor A, Golshan M,
Meric-Bernstam F
, Horton JK, Nanda R, Amos KD, Forero A, Hudis CA, Meszoely I, De Los Santos JF. Surgical patterns of care in patients with invasive breast cancer treated with neoadjuvant systemic therapy and breast magnetic resonance imaging: results of a secondary analysis of TBCRC 017. Ann Surg Oncol. 2015 Jan; 22(1):75-81.
PMID:
25059792
; PMCID:
PMC4370334
.
Citations:
4
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Zhou JH,
Rosen D
, Andreou A, Brouquet A, Abbott D,
Loyer E
, Gonzalez-Angulo AM,
Kopetz S
,
Meric-Bernstam F
,
Kuerer H
, Abdalla E,
Vauthey JN
,
Sahin AA
,
Maru DM
. Residual tumor thickness at the tumor-normal tissue interface predicts the recurrence-free survival in patients with liver metastasis of breast cancer. Ann Diagn Pathol. 2014 Oct; 18(5):266-70.
PMID:
25205085
; PMCID:
PMC4853197
.
Citations:
3
Fields:
Pat
Pathology
Translation:
Humans
Muranen T,
Meric-Bernstam F
,
Mills GB
. Promising rationally derived combination therapy with PI3K and CDK4/6 inhibitors. Cancer Cell. 2014 Jul 14; 26(1):7-9.
PMID:
25026206
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Morris VK
, Lucas FAS, Overman MJ,
Eng C
, Morelli MP, Jiang ZQ, Luthra R,
Meric-Bernstam F
,
Maru D
,
Scheet P
,
Kopetz S
, Vilar E. Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer. Ann Oncol. 2014 Oct; 25(10):2008-2014.
PMID:
25009008
; PMCID:
PMC4176451
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Jardim DL, Falchook G, Zinner R, Wheler JJ,
Janku F
,
Subbiah V
,
Piha-Paul SA
,
Fu S
,
Tannir N
,
Corn P
, Tang C,
Hess K
, Roy-Chowdhuri S, Kurzrock R,
Meric-Bernstam F
,
Hong DS
, de Melo Gagliato D. MET abnormalities in patients with genitourinary malignancies and outcomes with c-MET inhibitors. Clin Genitourin Cancer. 2015 Feb; 13(1):e19-26.
PMID:
25087088
; PMCID:
PMC5144738
.
Citations:
10
Fields:
Neo
Neoplasms
Uro
Urology
Translation:
Humans
Boland GM,
Meric-Bernstam F
. The role of surgeons in building a personalized medicine program. J Surg Oncol. 2015 Jan; 111(1):3-8.
PMID:
24964977
; PMCID:
PMC4285684
.
Citations:
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
de Melo Gagliato D, Jardim DL, Falchook G, Tang C, Zinner R, Wheler JJ,
Janku F
,
Subbiah V
,
Piha-Paul SA
,
Fu S
, Hess K, Roy-Chowdhuri S,
Moulder S
, Gonzalez-Angulo AM,
Meric-Bernstam F
,
Hong DS
. Analysis of MET genetic aberrations in patients with breast cancer at MD Anderson Phase I unit. Clin Breast Cancer. 2014 Dec; 14(6):468-74.
PMID:
25065564
; PMCID:
PMC4375949
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Janku F
, Vibat CR, Kosco K, Holley VR, Cabrilo G,
Meric-Bernstam F
, Stepanek VM,
Lin PP
, Leppin L, Hassaine L, Poole JC, Kurzrock R, Erlander MG. BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease. Oncotarget. 2014 Jun 15; 5(11):3607-10.
PMID:
25003820
; PMCID:
PMC4116506
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Meric-Bernstam F
,
Akcakanat A
, Chen H,
Sahin A
, Tarco E, Carkaci S,
Adrada BE
, Singh G,
Do KA
, Garces ZM,
Mittendorf E
,
Babiera G
,
Bedrosian I
,
Hwang R
,
Krishnamurthy S
,
Symmans WF
, Gonzalez-Angulo AM,
Mills GB
. Influence of biospecimen variables on proteomic biomarkers in breast cancer. Clin Cancer Res. 2014 Jul 15; 20(14):3870-83.
PMID:
24895461
; PMCID:
PMC4112583
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Akbani R
, Ng PK, Werner HM, Shahmoradgoli M, Zhang F, Ju Z, Liu W, Yang JY, Yoshihara K, Li J, Ling S, Seviour EG,
Ram PT
, Minna JD, Diao L, Tong P,
Heymach JV
, Hill SM, Dondelinger F,
Byers LA
,
Meric-Bernstam F
,
Weinstein JN
,
Broom BM
, Verhaak RG,
Liang H
, Mukherjee S,
Lu Y
,
Mills GB
, St?dler N. A pan-cancer proteomic perspective on The Cancer Genome Atlas. Nat Commun. 2014 May 29; 5:3887.
PMID:
24871328
; PMCID:
PMC4109726
.
Citations:
248
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Wheler JJ, Parker BA,
Lee JJ
, Atkins JT,
Janku F
,
Tsimberidou AM
, Zinner R,
Subbiah V
,
Fu S
, Schwab R,
Moulder S
,
Valero V
, Schwaederle M, Yelensky R, Miller VA, Stephens MP,
Meric-Bernstam F
, Kurzrock R. Unique molecular signatures as a hallmark of patients with metastatic breast cancer: implications for current treatment paradigms. Oncotarget. 2014 May 15; 5(9):2349-54.
PMID:
24811890
; PMCID:
PMC4058010
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Akcakanat A
,
Hong DS
,
Meric-Bernstam F
. Targeting translation initiation in breast cancer. Translation (Austin). 2014; 2(1):e28968.
PMID:
26779407
; PMCID:
PMC4705830
.
Citations:
1
Jardim DL, de Melo Gagliato D, Falchook GS,
Janku F
, Zinner R, Wheler JJ,
Subbiah V
,
Piha-Paul SA
,
Fu S
, Murphy MB,
Ajani J
, Tang C, Hess K,
Hamilton SR
, Roy-Chowdhuri S, Kurzrock R,
Meric-Bernstam F
,
Hong DS
. MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit. Oncotarget. 2014 Apr 15; 5(7):1837-45.
PMID:
24742823
; PMCID:
PMC4039117
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Rogith D, Yusuf RA, Hovick SR,
Peterson SK
, Burton-Chase AM,
Li Y
,
Meric-Bernstam F
,
Bernstam EV
. Attitudes regarding privacy of genomic information in personalized cancer therapy. J Am Med Inform Assoc. 2014 Oct; 21(e2):e320-5.
PMID:
24737606
; PMCID:
PMC4173182
.
Citations:
16
Fields:
Med
Medical Informatics
Translation:
Humans
Zeng J, Wu Y, Bailey A, Johnson A, Holla V,
Bernstam EV
, Xu H,
Meric-Bernstam F
. Adapting a natural language processing tool to facilitate clinical trial curation for personalized cancer therapy. AMIA Jt Summits Transl Sci Proc. 2014; 2014:126-31.
PMID:
25717412
; PMCID:
PMC4333699
.
Citations:
8
Gonzalez-Angulo AM,
Akcakanat A
,
Liu S
, Green MC, Murray JL, Chen H, Palla SL,
Koenig KB
,
Brewster AM
,
Valero V
,
Ibrahim NK
, Moulder-Thompson S, Litton JK, Tarco E, Moore J, Flores P, Crawford D, Dryden MJ,
Symmans WF
,
Sahin A
,
Giordano SH
, Pusztai L,
Do KA
,
Mills GB
, Hortobagyi GN,
Meric-Bernstam F
. Open-label randomized clinical trial of standard neoadjuvant chemotherapy with paclitaxel followed by FEC versus the combination of paclitaxel and everolimus followed by FEC in women with triple receptor-negative breast cancer?. Ann Oncol. 2014 Jun; 25(6):1122-7.
PMID:
24669015
; PMCID:
PMC4037860
.
Citations:
49
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Meric-Bernstam F
, Frampton GM, Ferrer-Lozano J, Yelensky R, Wang Y, Palmer GA, Ross JS, Miller VA,
Su X
, Eroles P, Barrera JA, Burgues O, Lluch AM, Zheng X,
Sahin A
, Stephens PJ,
Mills GB
, Cronin MT, Gonzalez-Angulo AM, P?rez-Fidalgo JA. Concordance of genomic alterations between primary and recurrent breast cancer. Mol Cancer Ther. 2014 May; 13(5):1382-9.
PMID:
24608573
; PMCID:
PMC4348062
.
Citations:
50
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Wagner JL,
Meric-Bernstam F
. Reply to letter: "Waiting time for breast cancer treatment". Ann Surg. 2014 Mar; 259(3):e50.
PMID:
24169189
.
Citations:
Fields:
Gen
General Surgery
Translation:
Humans