TitleAssistant Professor
InstitutionMD Anderson
DepartmentMolecular & Cellular Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lee HH, Wang YN, Yang WH, Xia W, Wei Y, Chan LC, Wang YH, Jiang Z, Xu S, Yao J, Qiu Y, Hsu YH, Hwang WL, Yan M, Cha JH, Hsu JL, Shen J, Ye Y, Wu X, Hou MF, Tseng LM, Wang SC, Pan MR, Yang CH, Wang YL, Yamaguchi H, Pang D, Hortobagyi GN, Yu D, Hung MC. Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation. Nat Commun. 2021 05 13; 12(1):2788. PMID: 33986289.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Feng R, Wang Y, Ramachandran V, Ma Q, May MM, Li M, Zhou JX, Xu X, Xu K, Fang S, Xia W, Sui D, Liu H, Gao X, Prieto V, Blacklow SC, Lu M, Lee JE. Characterization of novel neutralizing mouse monoclonal antibody JM1-24-3 developed against MUC18 in metastatic melanoma. J Exp Clin Cancer Res. 2020 Dec 05; 39(1):273. PMID: 33278894.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. Author Correction: PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol. 2020 Nov; 22(11):1396. PMID: 33033376.
      Citations: 1     Fields:    
    4. Liu C, Zha Z, Zhou C, Chen Y, Xia W, Wang YN, Lee HH, Yin Y, Yan M, Chang CW, Chan LC, Qiu Y, Li H, Li CW, Hsu JM, Hsu JL, Wang SC, Ren N, Hung MC. Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma. J Hepatol. 2021 04; 74(4):907-918. PMID: 33031845.
      Citations: 4     Fields:    
    5. Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol. 2020 10; 22(10):1264-1275. PMID: 32929201.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    6. Nie L, Wei Y, Zhang F, Hsu YH, Chan LC, Xia W, Ke B, Zhu C, Deng R, Tang J, Yao J, Chu YY, Zhao X, Han Y, Hou J, Huo L, Ko HW, Lin WC, Yamaguchi H, Hsu JM, Yang Y, Pan DN, Hsu JL, Kleer CG, Davidson NE, Hortobagyi GN, Hung MC. Author Correction: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer. Nat Commun. 2020 Jan 29; 11(1):673. PMID: 31996688.
      Citations: 1     Fields:    
    7. Nie L, Wei Y, Zhang F, Hsu YH, Chan LC, Xia W, Ke B, Zhu C, Deng R, Tang J, Yao J, Chu YY, Zhao X, Han Y, Hou J, Huo L, Ko HW, Lin WC, Yamaguchi H, Hsu JM, Yang Y, Pan DN, Hsu JL, Kleer CG, Davidson NE, Hortobagyi GN, Hung MC. CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer. Nat Commun. 2019 11 08; 10(1):5114. PMID: 31704972.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    8. Lee HH, Wang YN, Xia W, Chen CH, Rau KM, Ye L, Wei Y, Chou CK, Wang SC, Yan M, Tu CY, Hsia TC, Chiang SF, Chao KSC, Wistuba II, Hsu JL, Hortobagyi GN, Hung MC. Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy. Cancer Cell. 2019 08 12; 36(2):168-178.e4. PMID: 31327656.
      Citations: 69     Fields:    Translation:HumansCells
    9. Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC. IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion. J Clin Invest. 2019 07 15; 129(8):3324-3338. PMID: 31305264.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    10. Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR, Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han L, Lin C, Yang L. Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nat Immunol. 2019 07; 20(7):835-851. PMID: 31160797.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    11. Park MK, Yao Y, Xia W, Setijono SR, Kim JH, Vila IK, Chiu HH, Wu Y, Billalabeitia EG, Lee MG, Kalb RG, Hung MC, Pandolfi PP, Song SJ, Song MS. PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression. Nat Commun. 2019 02 07; 10(1):636. PMID: 30733438.
      Citations: 12     Fields:    Translation:AnimalsCells
    12. Li H, Li CW, Li X, Ding Q, Guo L, Liu S, Liu C, Lai CC, Hsu JM, Dong Q, Xia W, Hsu JL, Yamaguchi H, Du Y, Lai YJ, Sun X, Koller PB, Ye Q, Hung MC. MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1. Gastroenterology. 2019 05; 156(6):1849-1861.e13. PMID: 30711629.
      Citations: 47     Fields:    Translation:AnimalsCells
    13. Lee PC, Fang YF, Yamaguchi H, Wang WJ, Chen TC, Hong X, Ke B, Xia W, Wei Y, Zha Z, Wang Y, Kuo HP, Wang CW, Tu CY, Chen CH, Huang WC, Chiang SF, Nie L, Hou J, Chen CT, Huo L, Yang WH, Deng R, Nakai K, Hsu YH, Chang SS, Chiu TJ, Tang J, Zhang R, Wang L, Fang B, Chen T, Wong KK, Hsu JL, Hung MC. Targeting PKCd as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer. Cancer Cell. 2018 12 10; 34(6):954-969.e4. PMID: 30537515.
      Citations: 19     Fields:    Translation:HumansCells
    14. Yang Y, Hsu JM, Sun L, Chan LC, Li CW, Hsu JL, Wei Y, Xia W, Hou J, Qiu Y, Hung MC. Palmitoylation stabilizes PD-L1 to promote breast tumor growth. Cell Res. 2019 01; 29(1):83-86. PMID: 30514902.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    15. Jewell BE, Liu M, Lu L, Zhou R, Tu J, Zhu D, Huo Z, Xu A, Wang D, Mata H, Jin W, Xia W, Rao PH, Zhao R, Hung MC, Wang LL, Lee DF. Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation. Stem Cell Res. 2018 12; 33:36-40. PMID: 30312871.
      Citations:    Fields:    Translation:HumansCells
    16. Cha JH, Yang WH, Xia W, Wei Y, Chan LC, Lim SO, Li CW, Kim T, Chang SS, Lee HH, Hsu JL, Wang HL, Kuo CW, Chang WC, Hadad S, Purdie CA, McCoy AM, Cai S, Tu Y, Litton JK, Mittendorf EA, Moulder SL, Symmans WF, Thompson AM, Piwnica-Worms H, Chen CH, Khoo KH, Hung MC. Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Mol Cell. 2018 08 16; 71(4):606-620.e7. PMID: 30118680.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
    17. Yang Y, Li CW, Chan LC, Wei Y, Hsu JM, Xia W, Cha JH, Hou J, Hsu JL, Sun L, Hung MC. Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth. Cell Res. 2018 08; 28(8):862-864. PMID: 29959401.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    18. Yang WH, Cha JH, Xia W, Lee HH, Chan LC, Wang YN, Hsu JL, Ren G, Hung MC. Juxtacrine Signaling Inhibits Antitumor Immunity by Upregulating PD-L1 Expression. Cancer Res. 2018 07 15; 78(14):3761-3768. PMID: 29789418.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    19. Hsu JM, Xia W, Hsu YH, Chan LC, Yu WH, Cha JH, Chen CT, Liao HW, Kuo CW, Khoo KH, Hsu JL, Li CW, Lim SO, Chang SS, Chen YC, Ren GX, Hung MC. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018 05 15; 9(1):1908. PMID: 29765039.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    20. Wang YN, Lee HH, Chou CK, Yang WH, Wei Y, Chen CT, Yao J, Hsu JL, Zhu C, Ying H, Ye Y, Wang WJ, Lim SO, Xia W, Ko HW, Liu X, Liu CG, Wu X, Wang H, Li D, Prakash LR, Katz MH, Kang Y, Kim M, Fleming JB, Fogelman D, Javle M, Maitra A, Hung MC. Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer. Cancer Cell. 2018 04 09; 33(4):752-769.e8. PMID: 29606349.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    21. Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, Perillo EP, Dunn AK, Kuo CW, Khoo KH, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Huang TH, Sahin AA, Hortobagyi GN, Yoo SS, Hung MC. Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1. Cancer Cell. 2018 02 12; 33(2):187-201.e10. PMID: 29438695.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    22. Zhou R, Xu A, Wang D, Zhu D, Mata H, Huo Z, Tu J, Liu M, Mohamed AMT, Jewell BE, Gingold J, Xia W, Rao PH, Hung MC, Zhao R, Lee DF. A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing. Stem Cell Res. 2018 03; 27:131-135. PMID: 29414603.
      Citations: 4     Fields:    Translation:HumansCells
    23. Wang S, Liang K, Hu Q, Li P, Song J, Yang Y, Yao J, Mangala LS, Li C, Yang W, Park PK, Hawke DH, Zhou J, Zhou Y, Xia W, Hung MC, Marks JR, Gallick GE, Lopez-Berestein G, Flores ER, Sood AK, Huang S, Yu D, Yang L, Lin C. JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. J Clin Invest. 2017 12 01; 127(12):4498-4515. PMID: 29130936.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    24. Nakai K, Xia W, Liao HW, Saito M, Hung MC, Yamaguchi H. The role of PRMT1 in EGFR methylation and signaling in MDA-MB-468 triple-negative breast cancer cells. Breast Cancer. 2018 Jan; 25(1):74-80. PMID: 28643125.
      Citations: 11     Fields:    Translation:HumansCells
    25. Jiao S, Xia W, Yamaguchi H, Wei Y, Chen MK, Hsu JM, Hsu JL, Yu WH, Du Y, Lee HH, Li CW, Chou CK, Lim SO, Chang SS, Litton J, Arun B, Hortobagyi GN, Hung MC. PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression. Clin Cancer Res. 2017 Jul 15; 23(14):3711-3720. PMID: 28167507.
      Citations: 227     Fields:    Translation:HumansAnimalsCells
    26. Vila IK, Yao Y, Kim G, Xia W, Kim H, Kim SJ, Park MK, Hwang JP, González-Billalabeitia E, Hung MC, Song SJ, Song MS. A UBE2O-AMPKa2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy. Cancer Cell. 2017 02 13; 31(2):208-224. PMID: 28162974.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    27. Lim SO, Li CW, Xia W, Cha JH, Chan LC, Wu Y, Chang SS, Lin WC, Hsu JM, Hsu YH, Kim T, Chang WC, Hsu JL, Yamaguchi H, Ding Q, Wang Y, Yang Y, Chen CH, Sahin AA, Yu D, Hortobagyi GN, Hung MC. Deubiquitination and Stabilization of PD-L1 by CSN5. Cancer Cell. 2016 Dec 12; 30(6):925-939. PMID: 27866850.
      Citations: 185     Fields:    Translation:HumansAnimalsCells
    28. Wang Y, Hsu JM, Kang Y, Wei Y, Lee PC, Chang SJ, Hsu YH, Hsu JL, Wang HL, Chang WC, Li CW, Liao HW, Chang SS, Xia W, Ko HW, Chou CK, Fleming JB, Wang H, Hwang RF, Chen Y, Qin J, Hung MC. Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation. Cancer Res. 2016 12 01; 76(23):7049-7058. PMID: 27758883.
      Citations: 21     Fields:    Translation:HumansCells
    29. Ko HW, Lee HH, Huo L, Xia W, Yang CC, Hsu JL, Li LY, Lai CC, Chan LC, Cheng CC, Labaff AM, Liao HW, Lim SO, Li CW, Wei Y, Nie L, Yamaguchi H, Hung MC. GSK3ß inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers. Oncotarget. 2016 Aug 30; 7(35):57131-57144. PMID: 27494834.
      Citations: 12     Fields:    Translation:HumansCells
    30. Li CW, Lim SO, Xia W, Lee HH, Chan LC, Kuo CW, Khoo KH, Chang SS, Cha JH, Kim T, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Ding Q, Wang Y, Yao J, Lee CC, Wu HJ, Sahin AA, Allison JP, Yu D, Hortobagyi GN, Hung MC. Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity. Nat Commun. 2016 08 30; 7:12632. PMID: 27572267.
      Citations: 217     Fields:    Translation:HumansAnimalsCells
    31. Lim SO, Li CW, Xia W, Lee HH, Chang SS, Shen J, Hsu JL, Raftery D, Djukovic D, Gu H, Chang WC, Wang HL, Chen ML, Huo L, Chen CH, Wu Y, Sahin A, Hanash SM, Hortobagyi GN, Hung MC. EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape. Cancer Res. 2016 Mar 01; 76(5):1284-96. PMID: 26759242.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    32. Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, Wang Y, Chou CK, Hsu JM, Lai YJ, LaBaff AM, Ding Q, Ko HW, Tsai FJ, Tsai CH, Hortobagyi GN, Hung MC. AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation. Cancer Res. 2016 Mar 15; 76(6):1451-62. PMID: 26759241.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    33. Liao HW, Hsu JM, Xia W, Wang HL, Wang YN, Chang WC, Arold ST, Chou CK, Tsou PH, Yamaguchi H, Fang YF, Lee HJ, Lee HH, Tai SK, Yang MH, Morelli MP, Sen M, Ladbury JE, Chen CH, Grandis JR, Kopetz S, Hung MC. PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response. J Clin Invest. 2015 Dec; 125(12):4529-43. PMID: 26571401.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    34. Jiang Y, Fu Y, Xing XP, Li M, Wang O, Xia WB, Meng XW. Zoledronic acid-induced hepatotoxicity relieved after subsequent infusions in a Chinese woman with glucocorticoid-induced osteoporosis. Eur J Med Res. 2015 Aug 22; 20:68. PMID: 26297149.
      Citations: 1     Fields:    Translation:Humans
    35. Zhou PR, Xu XJ, Zhang ZL, Liao EY, Chen DC, Liu J, Wu W, Jiang Y, Wang O, Xia WB, Xing XP, Xu L, Li M. SOST polymorphisms and response to alendronate treatment in postmenopausal Chinese women with osteoporosis. Pharmacogenomics. 2015; 16(10):1077-88. PMID: 26250343.
      Citations: 4     Fields:    Translation:Humans
    36. Yuan L, Chen L, Liao RX, Lin YY, Jiang Y, Wang O, Li M, Xing XP, Pang QQ, Jiajue R, Xia WB. A Common Mutation and a Novel Mutation in the HPGD Gene in Nine Patients with Primary Hypertrophic Osteoarthropathy. Calcif Tissue Int. 2015 Oct; 97(4):336-42. PMID: 26135126.
      Citations: 10     Fields:    Translation:HumansCells
    37. Yang CC, LaBaff A, Wei Y, Nie L, Xia W, Huo L, Yamaguchi H, Hsu YH, Hsu JL, Liu D, Lang J, Du Y, Lien HC, Li LY, Deng R, Chan LC, Yao J, Kleer CG, Hortobagyi GN, Hung MC. Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers. Am J Transl Res. 2015; 7(6):1009-20. PMID: 26279746.
      Citations: 22     
    38. Lee DF, Su J, Kim HS, Chang B, Papatsenko D, Zhao R, Yuan Y, Gingold J, Xia W, Darr H, Mirzayans R, Hung MC, Schaniel C, Lemischka IR. Modeling familial cancer with induced pluripotent stem cells. Cell. 2015 Apr 09; 161(2):240-54. PMID: 25860607.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    39. Xu LJ, Jiang Y, Liao RX, Zhang HB, Mao JF, Chi Y, Li M, Wang O, Liu XQ, Liu ZY, Xing XP, Yu W, Xia WB. Low-dose adefovir dipivoxil may induce Fanconi syndrome: clinical characteristics and long-term follow-up for Chinese patients. Antivir Ther. 2015; 20(6):603-11. PMID: 25814481.
      Citations: 6     Fields:    Translation:HumansCells
    40. Huo L, Li CW, Huang TH, Lam YC, Xia W, Tu C, Chang WC, Hsu JL, Lee DF, Nie L, Yamaguchi H, Wang Y, Lang J, Li LY, Chen CH, Mishra L, Hung MC. Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. Am J Transl Res. 2014; 6(6):649-63. PMID: 25628777.
      Citations: 12     
    41. Thirumurthi U, Shen J, Xia W, LaBaff AM, Wei Y, Li CW, Chang WC, Chen CH, Lin HK, Yu D, Hung MC. MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer. Sci Signal. 2014 Jul 29; 7(336):ra71. PMID: 25074979.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    42. Chou RH, Wang YN, Hsieh YH, Li LY, Xia W, Chang WC, Chang LC, Cheng CC, Lai CC, Hsu JL, Chang WJ, Chiang SY, Lee HJ, Liao HW, Chuang PH, Chen HY, Wang HL, Kuo SC, Chen CH, Yu YL, Hung MC. EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4. Dev Cell. 2014 Jul 28; 30(2):224-37. PMID: 25073158.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    43. Khotskaya YB, Goverdhan A, Shen J, Ponz-Sarvise M, Chang SS, Hsu MC, Wei Y, Xia W, Yu D, Hung MC. S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer. Am J Transl Res. 2014; 6(4):361-76. PMID: 25075253.
      Citations: 25     
    44. Zhou PR, Liu HJ, Liao EY, Zhang ZL, Chen DC, Liu J, Wu W, Xing XP, Xia WB, Xu L, Li M. LRP5 polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis. Pharmacogenomics. 2014 Apr; 15(6):821-31. PMID: 24897288.
      Citations: 3     Fields:    Translation:Humans
    45. Kong J, Wang O, Nie M, Shi J, Jiang Y, Li M, Xia WB, Meng XW, Xing XP. [CDC73 gene mutation and parafibromin expression status of parathyroid carcinoma in Chinese]. Zhonghua Yi Xue Za Zhi. 2013 Nov 12; 93(42):3364-8. PMID: 24418033.
      Citations:    Fields:    Translation:Humans
    46. Zhao Z, Xia WB, Xing XP, Li M, Wang O, Jiang Y, Xu LJ, Li N. [Infantile hypophosphatasia due to mutations in the tissue-nonspecific alkaline phosphatase gene]. Zhonghua Nei Ke Za Zhi. 2013 Oct; 52(10):824-8. PMID: 24378058.
      Citations: 3     Fields:    Translation:Humans
    47. Wang X, Saso H, Iwamoto T, Xia W, Gong Y, Pusztai L, Woodward WA, Reuben JM, Warner SL, Bearss DJ, Hortobagyi GN, Hung MC, Ueno NT. TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase. Cancer Res. 2013 Nov 01; 73(21):6516-25. PMID: 24014597.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    48. Saldana SM, Lee HH, Lowery FJ, Khotskaya YB, Xia W, Zhang C, Chang SS, Chou CK, Steeg PS, Yu D, Hung MC. Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis. PLoS One. 2013; 8(9):e73406. PMID: 24039934.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    49. Khotskaya YB, Beck BH, Hurst DR, Han Z, Xia W, Hung MC, Welch DR. Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix. Mol Carcinog. 2014 Dec; 53(12):1011-26. PMID: 24000122.
      Citations: 9     Fields:    Translation:HumansCells
    50. Huang TH, Huo L, Wang YN, Xia W, Wei Y, Chang SS, Chang WC, Fang YF, Chen CT, Lang JY, Tu C, Wang Y, Hsu MC, Kuo HP, Ko HW, Shen J, Lee HH, Lee PC, Wu Y, Chen CH, Hung MC. Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers. Cancer Cell. 2013 Jun 10; 23(6):796-810. PMID: 23764002.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    51. Shen J, Xia W, Khotskaya YB, Huo L, Nakanishi K, Lim SO, Du Y, Wang Y, Chang WC, Chen CH, Hsu JL, Wu Y, Lam YC, James BP, Liu X, Liu CG, Patel DJ, Hung MC. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature. 2013 May 16; 497(7449):383-7. PMID: 23636329.
      Citations: 167     Fields:    Translation:HumansCells
    52. Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev. 2013 Feb 01; 27(3):274-87. PMID: 23388826.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    53. Li S, Xue HD, Jiang Y, Xia WB, Jing HL, Chen LB, Sun F, Jin ZY. Comparison of whole body diffusion weighted magnetic resonance imaging and somatostatin receptor scintigraphy for oncogenic osteomalacia. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Oct; 34(5):437-42. PMID: 23134817.
      Citations:    Fields:    Translation:Humans
    54. Jiang Y, Xia WB, Xing XP, Silva BC, Li M, Wang O, Zhang HB, Li F, Jing HL, Zhong DR, Jin J, Gao P, Zhou L, Qi F, Yu W, Bilezikian JP, Meng XW. Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature. J Bone Miner Res. 2012 Sep; 27(9):1967-75. PMID: 22532501.
      Citations: 65     Fields:    Translation:Humans
    55. Wang O, Wang CY, Shi J, Nie M, Xia WB, Li M, Jiang Y, Guan H, Meng XW, Xing XP. Expression of Ki-67, galectin-3, fragile histidine triad, and parafibromin in malignant and benign parathyroid tumors. Chin Med J (Engl). 2012 Aug; 125(16):2895-901. PMID: 22932087.
      Citations: 11     Fields:    Translation:Humans
    56. Zhang D, Lu L, Yang HB, Li M, Sun H, Zeng ZP, Li XP, Xia WB, Xing XP. Exome sequencing identifies compound heterozygous PKHD1 mutations as a cause of autosomal recessive polycystic kidney disease. Chin Med J (Engl). 2012 Jul; 125(14):2482-6. PMID: 22882926.
      Citations: 6     Fields:    Translation:Humans
    57. Wang Y, Ding Q, Yen CJ, Xia W, Izzo JG, Lang JY, Li CW, Hsu JL, Miller SA, Wang X, Lee DF, Hsu JM, Huo L, Labaff AM, Liu D, Huang TH, Lai CC, Tsai FJ, Chang WC, Chen CH, Wu TT, Buttar NS, Wang KK, Wu Y, Wang H, Ajani J, Hung MC. The crosstalk of mTOR/S6K1 and Hedgehog pathways. Cancer Cell. 2012 Mar 20; 21(3):374-87. PMID: 22439934.
      Citations: 174     Fields:    Translation:HumansAnimalsCells
    58. Li CW, Xia W, Huo L, Lim SO, Wu Y, Hsu JL, Chao CH, Yamaguchi H, Yang NK, Ding Q, Wang Y, Lai YJ, LaBaff AM, Wu TJ, Lin BR, Yang MH, Hortobagyi GN, Hung MC. Epithelial-mesenchymal transition induced by TNF-a requires NF-?B-mediated transcriptional upregulation of Twist1. Cancer Res. 2012 Mar 01; 72(5):1290-300. PMID: 22253230.
      Citations: 200     Fields:    Translation:HumansAnimalsCells
    59. Xia WB, He SL, Xu L, Liu AM, Jiang Y, Li M, Wang O, Xing XP, Sun Y, Cummings SR. Rapidly increasing rates of hip fracture in Beijing, China. J Bone Miner Res. 2012 Jan; 27(1):125-9. PMID: 21956596.
      Citations: 63     Fields:    Translation:Humans
    60. Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, Dhar D, Karin M, Chen CH, Hung MC. IKKa activation of NOTCH links tumorigenesis via FOXA2 suppression. Mol Cell. 2012 Jan 27; 45(2):171-84. PMID: 22196886.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    61. Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, Huo L, Cheng X, Chen YJ, Li CW, Jeng LB, Hsu JL, Li LY, Tan A, Curley SA, Ellis LM, Dubois RN, Hung MC. APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. J Clin Invest. 2011 Nov; 121(11):4526-36. PMID: 21985787.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    62. Li M, Xia WB, Xing XP, Yu W, Hu YY, Jiang Y, Wang O, Liu HJ, Han LW, Meng XW, Xu L. Benefit of infusions with ibandronate treatment in children with osteogenesis imperfecta. Chin Med J (Engl). 2011 Oct; 124(19):3049-53. PMID: 22040553.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    63. Sun XF, Zhang HB, Li XP, Xia WB, Xing XP, Meng XW. [A case of adefovir dipivoxil induced hypophosphataemic osteomalacia and literature review]. Zhonghua Nei Ke Za Zhi. 2011 Sep; 50(9):754-7. PMID: 22176963.
      Citations: 3     Fields:    Translation:Humans
    64. Le XF, Mao W, He G, Claret FX, Xia W, Ahmed AA, Hung MC, Siddik ZH, Bast RC. The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells. J Natl Cancer Inst. 2011 Sep 21; 103(18):1403-22. PMID: 21813412.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    65. Euhus D, Bu D, Xie XJ, Sarode V, Ashfaq R, Hunt K, Xia W, O'Shaughnessy J, Grant M, Arun B, Dooley W, Miller A, Flockhart D, Lewis C. Tamoxifen downregulates ets oncogene family members ETV4 and ETV5 in benign breast tissue: implications for durable risk reduction. Cancer Prev Res (Phila). 2011 Nov; 4(11):1852-62. PMID: 21778330.
      Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
    66. Chen CT, Yamaguchi H, Lee HJ, Du Y, Lee HH, Xia W, Yu WH, Hsu JL, Yen CJ, Sun HL, Wang Y, Yeh ET, Hortobagyi GN, Hung MC. Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase. Mol Cancer Ther. 2011 Aug; 10(8):1327-36. PMID: 21610170.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    67. Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, Yu WH, Rehman SK, Hsu JL, Lee HH, Liu M, Chen CT, Yu D, Hung MC. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol. 2011 Mar; 13(3):317-23. PMID: 21336307.
      Citations: 338     Fields:    Translation:HumansCells
    68. Chang CJ, Yang JY, Xia W, Chen CT, Xie X, Chao CH, Woodward WA, Hsu JM, Hortobagyi GN, Hung MC. EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-ß-catenin signaling. Cancer Cell. 2011 Jan 18; 19(1):86-100. PMID: 21215703.
      Citations: 193     Fields:    Translation:HumansAnimalsCells
    69. Tsai WW, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S, Tsai CY, Shi X, Schwarzer D, Plunkett W, Aronow B, Gozani O, Fischle W, Hung MC, Patel DJ, Barton MC. TRIM24 links a non-canonical histone signature to breast cancer. Nature. 2010 Dec 16; 468(7326):927-32. PMID: 21164480.
      Citations: 189     Fields:    Translation:HumansCells
    70. Cheng X, Xia W, Yang JY, Hsu JL, Chou CK, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of p21(CIP1/WAF1) in mammary epithelium accelerates mammary tumorigenesis and promotes lung metastasis. Biochem Biophys Res Commun. 2010 Dec 03; 403(1):103-7. PMID: 21040707.
      Citations: 13     Fields:    Translation:HumansAnimals
    71. Zhu Y, Zhang HB, Lu L, Li NS, Fu Y, Wang O, Xu LL, Jiang Y, Tong AL, Zhu HJ, Li W, Hu MM, Yu M, Mao JF, Yuan T, Li M, Xia WB, Xing XP. [Adrenal lesions in patients of multiple endocrine neoplasia type 1]. Zhonghua Yi Xue Za Zhi. 2010 Oct 19; 90(38):2689-92. PMID: 21162898.
      Citations:    Fields:    Translation:Humans
    72. Cheng X, Xia W, Yang JY, Hsu JL, Lang JY, Chou CK, Du Y, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of murine double minute 2 by Akt in mammary epithelium delays mammary involution and accelerates mammary tumorigenesis. Cancer Res. 2010 Oct 01; 70(19):7684-9. PMID: 20841468.
      Citations: 9     Fields:    Translation:AnimalsCells
    73. Huo L, Wang YN, Xia W, Hsu SC, Lai CC, Li LY, Chang WC, Wang Y, Hsu MC, Yu YL, Huang TH, Ding Q, Chen CH, Tsai CH, Hung MC. RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16125-30. PMID: 20802156.
      Citations: 53     Fields:    Translation:HumansCells
    74. Wang CY, Wang O, Nie M, Zhao DC, Xia WB, Li M, Guan H, Meng XW, Xing XP. [Clinical and molecular genetic analyses for a sporadic parathyroid carcinoma]. Zhonghua Yi Xue Za Zhi. 2010 Jun 22; 90(24):1694-7. PMID: 20979880.
      Citations:    Fields:    Translation:Humans
    75. Yang JY, Chang CJ, Xia W, Wang Y, Wong KK, Engelman JA, Du Y, Andreeff M, Hortobagyi GN, Hung MC. Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer. Cancer Res. 2010 Jun 01; 70(11):4709-18. PMID: 20484037.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    76. Xia WB, Jiang Y, Li M, Xing XP, Wang O, Hu YY, Zhang HB, Liu HC, Meng XW, Zhou XY. Levels and dynamic changes of serum fibroblast growth factor 23 in hypophosphatemic rickets/osteomalacia. Chin Med J (Engl). 2010 May 05; 123(9):1158-62. PMID: 20529556.
      Citations: 5     Fields:    Translation:Humans
    77. Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, Xing G, Zhao Y, Lin CH, Tsai SF, Fidler IJ, Hung MC. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal. 2010 Feb 09; 3(108):ra9. PMID: 20145209.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    78. Xia WJ, Ye X, Tian LW, Xu XZ, Chen YK, Luo GP, Bei CH, Deng J, Santoso S, Fu YS. Establishment of platelet donor registry improves the treatment of platelet transfusion refractoriness in Guangzhou region of China. Transfus Med. 2010 Aug 01; 20(4):269-74. PMID: 20136782.
      Citations: 1     Fields:    Translation:Humans
    79. Bui-Nguyen TM, Pakala SB, Sirigiri RD, Xia W, Hung MC, Sarin SK, Kumar V, Slagle BL, Kumar R. NF-kappaB signaling mediates the induction of MTA1 by hepatitis B virus transactivator protein HBx. Oncogene. 2010 Feb 25; 29(8):1179-89. PMID: 20010875.
      Citations: 24     Fields:    Translation:HumansCells
    80. Andre F, Xia W, Conforti R, Wei Y, Boulet T, Tomasic G, Spielmann M, Zoubir M, Berrada N, Arriagada R, Hortobagyi GN, Hung MC, Pusztai L, Delaloge S, Michiels S, Cristofanilli M. CXCR4 expression in early breast cancer and risk of distant recurrence. Oncologist. 2009 Dec; 14(12):1182-8. PMID: 19939894.
      Citations: 30     Fields:    Translation:Humans
    81. Li M, Xing XP, Zhang ZL, Liu JL, Zhang ZL, Liu DG, Xia WB, Meng XW. Infusion of ibandronate once every 3 months effectively decreases bone resorption markers and increases bone mineral density in Chinese postmenopausal osteoporotic women: a 1-year study. J Bone Miner Metab. 2010 May; 28(3):299-305. PMID: 19855926.
      Citations: 4     Fields:    Translation:Humans
    82. Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Chen CT, Huo L, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, Chang YH, Tsai SF, Li LY, Hung MC. KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Mol Cell. 2009 Oct 09; 36(1):131-40. PMID: 19818716.
      Citations: 140     Fields:    Translation:HumansAnimalsCells
    83. Kuo HP, Lee DF, Xia W, Wei Y, Hung MC. TNFalpha induces HIF-1alpha expression through activation of IKKbeta. Biochem Biophys Res Commun. 2009 Nov 27; 389(4):640-4. PMID: 19766100.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    84. Han GY, Wang O, Xing XP, Meng XW, Lian XL, Guan H, Ye W, Xia WB, Li M, Jiang Y, Hu YY, Liu HC, Cui QC. [The efficacy and safety of intravenous bisphosphonates in the treatment of primary hyperparathyroidism complicated by hypercalcemia crisis]. Zhonghua Nei Ke Za Zhi. 2009 Sep; 48(9):729-33. PMID: 20079207.
      Citations: 2     Fields:    Translation:Humans
    85. Kuo HP, Lee DF, Xia W, Lai CC, Li LY, Hung MC. Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation. Biochem Biophys Res Commun. 2009 Nov 06; 389(1):156-61. PMID: 19716809.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    86. Xie X, Hsu JL, Choi MG, Xia W, Yamaguchi H, Chen CT, Trinh BQ, Lu Z, Ueno NT, Wolf JK, Bast RC, Hung MC. A novel hTERT promoter-driven E1A therapeutic for ovarian cancer. Mol Cancer Ther. 2009 Aug; 8(8):2375-82. PMID: 19671744.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    87. Xia W, Wei Y, Du Y, Liu J, Chang B, Yu YL, Huo LF, Miller S, Hung MC. Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer. Mol Carcinog. 2009 Jul; 48(7):610-7. PMID: 19058255.
      Citations: 81     Fields:    Translation:HumansCells
    88. He XD, Xia WB, Xing XP, Li M, Jiang Y, Wang O, Xu LL, Xu JP. [Clinical features of pregnancy and lactation-associated osteoporosis: analysis of 4 cases]. Zhonghua Yi Xue Za Zhi. 2009 Apr 14; 89(14):983-5. PMID: 19671313.
      Citations: 2     Fields:    Translation:Humans
    89. Xia WB, Zhang ZL, Wang HF, Meng XW, Zhang Y, Zhu GY, Xing XP, Liu JL, Wang LH, Jiang Y, Weng SF, Xu T, Hu YY, Yu W, Tian JP. The efficacy and safety of calcitriol and/or Caltrate D in elderly Chinese women with low bone mass. Acta Pharmacol Sin. 2009 Mar; 30(3):372-8. PMID: 19262561.
      Citations: 6     Fields:    Translation:Humans
    90. Wang O, Xing XP, Meng XW, Xia WB, Li M, Jiang Y, Hu YY, Liu HC. Treatment of hypocalcemia caused by hypoparathyroidism or pseudohypoparathyroidism with domestic-made calcitriol: a prospective and self-controlled clinical trial. Chin Med J (Engl). 2009 Feb 05; 122(3):279-83. PMID: 19236804.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    91. Wei Y, Xia W, Zhang Z, Liu J, Wang H, Adsay NV, Albarracin C, Yu D, Abbruzzese JL, Mills GB, Bast RC, Hortobagyi GN, Hung MC. Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers. Mol Carcinog. 2008 Sep; 47(9):701-6. PMID: 18176935.
      Citations: 109     Fields:    Translation:Humans
    92. Ding Q, Huo L, Yang JY, Xia W, Wei Y, Liao Y, Chang CJ, Yang Y, Lai CC, Lee DF, Yen CJ, Chen YJ, Hsu JM, Kuo HP, Lin CY, Tsai FJ, Li LY, Tsai CH, Hung MC. Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Res. 2008 Aug 01; 68(15):6109-17. PMID: 18676833.
      Citations: 77     Fields:    Translation:HumansCells
    93. Hung LY, Tseng JT, Lee YC, Xia W, Wang YN, Wu ML, Chuang YH, Lai CH, Chang WC. Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression. Nucleic Acids Res. 2008 Aug; 36(13):4337-51. PMID: 18586824.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    94. Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat Cell Biol. 2008 Feb; 10(2):138-48. PMID: 18204439.
      Citations: 300     Fields:    Translation:HumansAnimalsCells
    95. Lo HW, Hsu SC, Xia W, Cao X, Shih JY, Wei Y, Abbruzzese JL, Hortobagyi GN, Hung MC. Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression. Cancer Res. 2007 Oct 01; 67(19):9066-76. PMID: 17909010.
      Citations: 264     Fields:    Translation:HumansAnimalsCells
    96. Wang X, Zheng M, Liu G, Xia W, McKeown-Longo PJ, Hung MC, Zhao J. Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Cancer Res. 2007 Aug 01; 67(15):7184-93. PMID: 17671186.
      Citations: 82     Fields:    Translation:HumansCells
    97. Xie X, Xia W, Li Z, Kuo HP, Liu Y, Li Z, Ding Q, Zhang S, Spohn B, Yang Y, Wei Y, Lang JY, Evans DB, Chiao PJ, Abbruzzese JL, Hung MC. Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. Cancer Cell. 2007 Jul; 12(1):52-65. PMID: 17613436.
      Citations: 38     Fields:    Translation:Animals
    98. Jiang Y, Meng XW, Lu ZL, Xia WB, Xing XP, Li M, Wang O, Yu W, Tian JP. [Bone loss is more severe in younger Cushing's syndrome women than in older ones: comparison of bone mineral density between Cushing's syndrome and healthy women]. Zhonghua Yi Xue Za Zhi. 2007 Jun 26; 87(24):1695-7. PMID: 17825152.
      Citations:    Fields:    Translation:Humans
    99. Ding Q, He X, Xia W, Hsu JM, Chen CT, Li LY, Lee DF, Yang JY, Xie X, Liu JC, Hung MC. Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer. Cancer Res. 2007 May 15; 67(10):4564-71. PMID: 17495324.
      Citations: 98     Fields:    Translation:HumansCells
    100. Ding Q, He X, Hsu JM, Xia W, Chen CT, Li LY, Lee DF, Liu JC, Zhong Q, Wang X, Hung MC. Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. Mol Cell Biol. 2007 Jun; 27(11):4006-17. PMID: 17387146.
      Citations: 191     Fields:    Translation:HumansAnimalsCells
    101. Yu LY, Pei Y, Xia WB, Xing XP, Meng XW, Zhou XY. Effect of fibroblast growth factor 9 on Runx2 gene promoter activity in MC3T3-E1 and C2C12 cells. Chin Med J (Engl). 2007 Mar 20; 120(6):491-5. PMID: 17439743.
      Citations: 2     Fields:    Translation:AnimalsCells
    102. Wang O, Meng XW, Xing XP, Xia WB, Li M, Xu L, Zhou XY, Jiao J, Hu YY, Liu HC. [Association of calcium-sensing receptor gene polymorphism with serum calcium level in healthy young Han women in Beijing]. Zhonghua Nei Ke Za Zhi. 2007 Jan; 46(1):43-7. PMID: 17331389.
      Citations: 1     Fields:    Translation:Humans
    103. Ning ZW, Wang O, Pei Y, Meng XW, Xing XP, Xia WB, Li M, Zhou XY, Zeng ZP. [RET gene cys 634 trp mutation in a multiple endocrine neoplasia type 2A kindred]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006 Dec; 28(6):799-802. PMID: 17260470.
      Citations:    Fields:    Translation:Humans
    104. Wang SC, Nakajima Y, Yu YL, Xia W, Chen CT, Yang CC, McIntush EW, Li LY, Hawke DH, Kobayashi R, Hung MC. Tyrosine phosphorylation controls PCNA function through protein stability. Nat Cell Biol. 2006 Dec; 8(12):1359-68. PMID: 17115032.
      Citations: 143     Fields:    Translation:HumansCells
    105. Ping B, He X, Xia W, Lee DF, Wei Y, Yu D, Mills G, Shi D, Hung MC. Cytoplasmic expression of p21CIP1/WAF1 is correlated with IKKbeta overexpression in human breast cancers. Int J Oncol. 2006 Nov; 29(5):1103-10. PMID: 17016640.
      Citations: 9     Fields:    Translation:HumansCells
    106. Yang JY, Zong CS, Xia W, Wei Y, Ali-Seyed M, Li Z, Broglio K, Berry DA, Hung MC. MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation. Mol Cell Biol. 2006 Oct; 26(19):7269-82. PMID: 16980628.
      Citations: 96     Fields:    Translation:HumansCells
    107. Yang JY, Xia W, Hu MC. Ionizing radiation activates expression of FOXO3a, Fas ligand, and Bim, and induces cell apoptosis. Int J Oncol. 2006 Sep; 29(3):643-8. PMID: 16865280.
      Citations: 55     Fields:    Translation:HumansCells
    108. Yu Z, Xia W, Wang HY, Wang SC, Pan Y, Kwong KY, Hortobagyi GN, Hung MC. Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1. Mol Carcinog. 2006 Sep; 45(9):667-75. PMID: 16652376.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    109. Xia WY, Lien HC, Wang SC, Pan Y, Sahin A, Kuo YH, Chang KJ, Zhou X, Wang H, Yu Z, Hortobagyi G, Shi DR, Hung MC. Expression of PEA3 and lack of correlation between PEA3 and HER-2/neu expression in breast cancer. Breast Cancer Res Treat. 2006 Aug; 98(3):295-301. PMID: 16752078.
      Citations: 8     Fields:    Translation:Humans
    110. Bartholomeusz G, Wu Y, Ali Seyed M, Xia W, Kwong KY, Hortobagyi G, Hung MC. Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis. Mol Carcinog. 2006 Feb; 45(2):73-83. PMID: 16302269.
      Citations: 20     Fields:    Translation:HumansCells
    111. Li M, Jiao J, Meng XW, Zhou XY, Xing XP, Xia WB, Wang O, Jiang Y, Liu HC, Hu YY. [Skeletal biomechanical properties improvement in ovariectomized osteoporotic rats of teriparatide was retarded by alendronate]. Zhonghua Nei Ke Za Zhi. 2006 Feb; 45(2):104-7. PMID: 16624115.
      Citations:    Fields:    Translation:Animals
    112. Vorburger SA, Hetrakul N, Xia W, Wilson-Heiner M, Mirza N, Pollock RE, Feig B, Swisher SG, Hunt KK. Gene therapy with E2F-1 up-regulates the protein kinase PKR and inhibits growth of leiomyosarcoma in vivo. Mol Cancer Ther. 2005 Nov; 4(11):1710-6. PMID: 16275992.
      Citations: 9     Translation:AnimalsCells
    113. Cha TL, Zhou BP, Xia W, Wu Y, Yang CC, Chen CT, Ping B, Otte AP, Hung MC. Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science. 2005 Oct 14; 310(5746):306-10. PMID: 16224021.
      Citations: 254     Fields:    Translation:HumansAnimalsCells
    114. Ding Q, Xia W, Liu JC, Yang JY, Lee DF, Xia J, Bartholomeusz G, Li Y, Pan Y, Li Z, Bargou RC, Qin J, Lai CC, Tsai FJ, Tsai CH, Hung MC. Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell. 2005 Jul 22; 19(2):159-70. PMID: 16039586.
      Citations: 241     Fields:    Translation:HumansCells
    115. Jia N, Huang CJ, Li WH, Li YX, Xia WB, Xing XP, Meng XW, Ma L, Lu ZH. [Mandibular myofibroblastic tumor complicated with hypophosphatemic anti-vitamin D osteomalacia--a case report]. Zhonghua Yi Xue Za Zhi. 2005 Jun 22; 85(23):1655. PMID: 16185542.
      Citations:    Fields:    Translation:Humans
    116. Lo HW, Hsu SC, Ali-Seyed M, Gunduz M, Xia W, Wei Y, Bartholomeusz G, Shih JY, Hung MC. Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway. Cancer Cell. 2005 Jun; 7(6):575-89. PMID: 15950906.
      Citations: 225     Fields:    Translation:HumansAnimalsCells
    117. Shao R, Lee DF, Wen Y, Ding Y, Xia W, Ping B, Yagita H, Spohn B, Hung MC. E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation. Mol Cancer Res. 2005 Apr; 3(4):219-26. PMID: 15831675.
      Citations: 4     Fields:    Translation:HumansCells
    118. Li M, Jiao J, Meng XW, Xing XP, Xia WB, Zhou XY, Liu HC, Jiang Y, Wang O, Hu YY, Zhan ZW. [Effects of teriparatide and alendronate on bone mineral density of osteoporotic rats]. Zhonghua Yi Xue Za Zhi. 2005 Feb 02; 85(5):335-8. PMID: 15854512.
      Citations: 1     Fields:    Translation:Animals
    119. Lo HW, Xia W, Wei Y, Ali-Seyed M, Huang SF, Hung MC. Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer. Cancer Res. 2005 Jan 01; 65(1):338-48. PMID: 15665312.
      Citations: 119     Fields:    Translation:HumansCells
    120. Li YM, Pan Y, Wei Y, Cheng X, Zhou BP, Tan M, Zhou X, Xia W, Hortobagyi GN, Yu D, Hung MC. Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. Cancer Cell. 2004 Nov; 6(5):459-69. PMID: 15542430.
      Citations: 202     Fields:    Translation:HumansAnimalsCells
    121. Zhou BP, Deng J, Xia W, Xu J, Li YM, Gunduz M, Hung MC. Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol. 2004 Oct; 6(10):931-40. PMID: 15448698.
      Citations: 678     Fields:    Translation:HumansCells
    122. Liao Y, Zou YY, Xia WY, Hung MC. Enhanced paclitaxel cytotoxicity and prolonged animal survival rate by a nonviral-mediated systemic delivery of E1A gene in orthotopic xenograft human breast cancer. Cancer Gene Ther. 2004 Sep; 11(9):594-602. PMID: 15272313.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    123. Wang SC, Lien HC, Xia W, Chen IF, Lo HW, Wang Z, Ali-Seyed M, Lee DF, Bartholomeusz G, Ou-Yang F, Giri DK, Hung MC. Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2. Cancer Cell. 2004 Sep; 6(3):251-61. PMID: 15380516.
      Citations: 129     Fields:    Translation:HumansCells
    124. Xia W, Chen JS, Zhou X, Sun PR, Lee DF, Liao Y, Zhou BP, Hung MC. Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients. Clin Cancer Res. 2004 Jun 01; 10(11):3815-24. PMID: 15173090.
      Citations: 61     Fields:    Translation:HumansCells
    125. Li M, Xia WB, Jin ZM, Shi H, Meng X, Xing X. [Report of a case with Alstrom syndrome]. Zhonghua Er Ke Za Zhi. 2004 Jun; 42(6):471. PMID: 15265447.
      Citations: 1     Fields:    Translation:Humans
    126. Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, Zou Y, Bao S, Hanada N, Saso H, Kobayashi R, Hung MC. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell. 2004 Apr 16; 117(2):225-37. PMID: 15084260.
      Citations: 365     Fields:    Translation:HumansAnimalsCells
    127. Jiao J, Meng XW, Xing XP, Zhou XY, Li M, Xia WB, Xu L, Tian JP, Yu W. [Bone mineral density and leptin receptor polymorphism Gln223Arg in Han women in Beijing]. Zhonghua Nei Ke Za Zhi. 2004 Apr; 43(4):276-9. PMID: 15130412.
      Citations: 1     Fields:    Translation:Humans
    128. Yan DH, Wen Y, Su LK, Xia W, Wang SC, Zhang S, Gan L, Lee DF, Spohn B, Frey JA, Hortobagyi GN, Hung MC. A delayed chemically induced tumorigenesis in Brca2 mutant mice. Oncogene. 2004 Mar 11; 23(10):1896-901. PMID: 14981540.
      Citations: 4     Fields:    Translation:AnimalsCells
    129. Lee CM, Lo HW, Shao RP, Wang SC, Xia W, Gershenson DM, Hung MC. Selective activation of ceruloplasmin promoter in ovarian tumors: potential use for gene therapy. Cancer Res. 2004 Mar 01; 64(5):1788-93. PMID: 14996741.
      Citations: 9     Fields:    Translation:HumansCells
    130. Deng J, Xia W, Miller SA, Wen Y, Wang HY, Hung MC. Crossregulation of NF-kappaB by the APC/GSK-3beta/beta-catenin pathway. Mol Carcinog. 2004 Mar; 39(3):139-46. PMID: 14991743.
      Citations: 34     Fields:    Translation:HumansCells
    131. Li M, Meng XW, Zhou XY, Xing XP, Xia WB, Liu HC. [Effects of different human parathyroid hormone 1-34 administration on SaoS-2 cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Feb; 26(1):30-3. PMID: 15052770.
      Citations:    Fields:    Translation:HumansCells
    132. Royce ME, Xia W, Sahin AA, Katayama H, Johnston DA, Hortobagyi G, Sen S, Hung MC. STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis. Cancer. 2004 Jan 01; 100(1):12-9. PMID: 14692019.
      Citations: 20     Fields:    Translation:HumansCells
    133. Hoque A, Carter J, Xia W, Hung MC, Sahin AA, Sen S, Lippman SM. Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast. Cancer Epidemiol Biomarkers Prev. 2003 Dec; 12(12):1518-22. PMID: 14693746.
      Citations: 28     Fields:    Translation:Humans
    134. Zhang ZL, Meng XW, Xing XP, Wang O, Xia WB, Li M, Jiang Y, Fu Y, Zhou XY. [Prospective study of pamidronate disodium in treatment of Paget's disease of bone]. Zhonghua Yi Xue Za Zhi. 2003 Oct 10; 83(19):1653-6. PMID: 14642096.
      Citations: 1     Fields:    Translation:Humans
    135. Pei Y, Meng XW, Zhou XY, Xing XP, Xia WB. Expression of core binding factor alpha1 up-regulated by IGF-I, GM-CSF, and EGF through MAPK pathway in MC3T3-E1 and C2C12 cells. Acta Pharmacol Sin. 2003 Oct; 24(10):975-84. PMID: 14531938.
      Citations: 4     Fields:    Translation:AnimalsCells
    136. Wen Y, Giri D, Yan DH, Spohn B, Zinner RG, Xia W, Thompson TC, Matusik RJ, Hung MC. Prostate-specific antitumor activity by probasin promoter-directed p202 expression. Mol Carcinog. 2003 Jul; 37(3):130-7. PMID: 12884364.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    137. Pei Y, Zhou XY, Meng XW, Xia WB, Xing XP, Liu HC, Hu YY. [Interaction effects between 1,25-dihydroxyvitamin D3 and transforming growth factor-beta1 on the proliferation and differentiation of human embryonic osteoblasts]. Zhonghua Yi Xue Za Zhi. 2003 Jun 25; 83(12):1084-8. PMID: 12899784.
      Citations: 1     Fields:    Translation:HumansCells
    138. Ning ZW, Wang O, Xu JY, Zhang JX, Li F, Xing XP, Meng XW, Xia WB, Li M, Guan H, Zhu Y. [Assessment of preoperative localization techniques for patients with primary hyperparathyroidism]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003 Jun; 25(3):280-4. PMID: 12905740.
      Citations: 1     Fields:    Translation:Humans
    139. Hu YY, Xia WB, Liu HC, Meng XW, Zhou XY, Xing XP. [Changes of urinary deoxypyridinoline crosslink/creatinine in rats after ovariectomy and anti-osteoporotic intervention]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003 Jun; 25(3):271-4. PMID: 12905738.
      Citations:    Fields:    Translation:Animals
    140. Xing XP, Xia WB, Meng XW, Zhou XY, Hu YY, Liu HC. [Evaluation of bone architecture and biomechanic properties by peripheral quantitative computed tomography in rats]. Zhonghua Yi Xue Za Zhi. 2003 May 10; 83(9):791-5. PMID: 12899761.
      Citations: 1     Fields:    Translation:Animals
    141. Lee CM, Shvartsman H, Deavers MT, Wang SC, Xia W, Schmandt R, Bodurka DC, Atkinson EN, Malpica A, Gershenson DM, Hung MC, Lu KH. beta-catenin nuclear localization is associated with grade in ovarian serous carcinoma. Gynecol Oncol. 2003 Mar; 88(3):363-8. PMID: 12648588.
      Citations: 22     Fields:    Translation:HumansCells
    142. Zhang ZL, Zhao JX, Meng XW, Zhou XY, Xing XP, Xia WB. [Association of polymorphisms of vitamin D receptor gene start codon and 3'-end region with bone mineral density in postmenopausal women]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Feb; 20(1):5-8. PMID: 12579489.
      Citations: 8     Fields:    Translation:Humans
    143. Ueno NT, Bartholomeusz C, Xia W, Anklesaria P, Bruckheimer EM, Mebel E, Paul R, Li S, Yo GH, Huang L, Hung MC. Systemic gene therapy in human xenograft tumor models by liposomal delivery of the E1A gene. Cancer Res. 2002 Nov 15; 62(22):6712-6. PMID: 12438271.
      Citations: 15     Fields:    Translation:Humans
    144. Ding Y, Wen Y, Spohn B, Wang L, Xia W, Kwong KY, Shao R, Li Z, Hortobagyi GN, Hung MC, Yan DH. Proapoptotic and antitumor activities of adenovirus-mediated p202 gene transfer. Clin Cancer Res. 2002 Oct; 8(10):3290-7. PMID: 12374701.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    145. Deng J, Miller SA, Wang HY, Xia W, Wen Y, Zhou BP, Li Y, Lin SY, Hung MC. beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell. 2002 Oct; 2(4):323-34. PMID: 12398896.
      Citations: 137     Fields:    Translation:HumansCells
    146. Vorburger SA, Pataer A, Yoshida K, Barber GN, Xia W, Chiao P, Ellis LM, Hung MC, Swisher SG, Hunt KK. Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis. Oncogene. 2002 Sep 12; 21(41):6278-88. PMID: 12214268.
      Citations: 11     Fields:    Translation:HumansCells
    147. Xing XP, Meng XW, Cheng ZQ, Zhan ZW, Chui ZH, Xia WB, Zhou XY. [Precision of rat BMD measurements by dual-energy X-ray absorptiometry in vitro]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2002 Jun; 24(3):302-5. PMID: 12905640.
      Citations:    Fields:    Translation:Animals
    148. Deng J, Kloosterbooer F, Xia W, Hung MC. The NH(2)-terminal and conserved region 2 domains of adenovirus E1A mediate two distinct mechanisms of tumor suppression. Cancer Res. 2002 Jan 15; 62(2):346-50. PMID: 11809676.
      Citations: 5     Fields:    Translation:AnimalsCells
    149. Li Z, Xia W, Fang B, Yan DH. Targeting HER-2/neu-overexpressing breast cancer cells by an antisense iron responsive element-directed gene expression. Cancer Lett. 2001 Dec 28; 174(2):151-8. PMID: 11689290.
      Citations: 1     Fields:    Translation:HumansCells
    150. Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat Cell Biol. 2001 Nov; 3(11):973-82. PMID: 11715018.
      Citations: 306     Fields:    Translation:HumansAnimalsCells
    151. Wang SC, Makino K, Xia W, Kim JS, Im SA, Peng H, Mok SC, Singletary SE, Hung MC. DOC-2/hDab-2 inhibits ILK activity and induces anoikis in breast cancer cells through an Akt-independent pathway. Oncogene. 2001 Oct 18; 20(47):6960-4. PMID: 11687976.
      Citations: 18     Fields:    Translation:HumansCells
    152. Lin SY, Makino K, Xia W, Matin A, Wen Y, Kwong KY, Bourguignon L, Hung MC. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol. 2001 Sep; 3(9):802-8. PMID: 11533659.
      Citations: 384     Fields:    Translation:HumansAnimalsCells
    153. Hortobagyi GN, Ueno NT, Xia W, Zhang S, Wolf JK, Putnam JB, Weiden PL, Willey JS, Carey M, Branham DL, Payne JY, Tucker SD, Bartholomeusz C, Kilbourn RG, De Jager RL, Sneige N, Katz RL, Anklesaria P, Ibrahim NK, Murray JL, Theriault RL, Valero V, Gershenson DM, Bevers MW, Huang L, Lopez-Berestein G, Hung MC. Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial. J Clin Oncol. 2001 Jul 15; 19(14):3422-33. PMID: 11454891.
      Citations: 28     Fields:    Translation:HumansCellsCTClinical Trials
    154. Cai ZJ, Yin DH, Li L, Xia WJ. [Investigation on quality difference between Cordyceps of Sichuan and those of Xizang]. Zhongguo Zhong Yao Za Zhi. 2001 Jul; 26(7):450-2. PMID: 12776356.
      Citations: 2     Fields:    Translation:Animals
    155. Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC. Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat Cell Biol. 2001 Mar; 3(3):245-52. PMID: 11231573.
      Citations: 342     Fields:    Translation:AnimalsCells
    156. Newman L, Xia W, Yang HY, Sahin A, Bondy M, Lukmanji F, Hung MC, Lee MH. Correlation of p27 protein expression with HER-2/neu expression in breast cancer. Mol Carcinog. 2001 Mar; 30(3):169-75. PMID: 11301477.
      Citations: 16     Fields:    Translation:Humans
    157. Xu F, Xia W, Luo RZ, Peng H, Zhao S, Dai J, Long Y, Zou L, Le W, Liu J, Parlow AF, Hung MC, Bast RC, Yu Y. The human ARHI tumor suppressor gene inhibits lactation and growth in transgenic mice. Cancer Res. 2000 Sep 01; 60(17):4913-20. PMID: 10987306.
      Citations: 15     Fields:    Translation:AnimalsCells
    158. Shao R, Xia W, Hung MC. Inhibition of angiogenesis and induction of apoptosis are involved in E1A-mediated bystander effect and tumor suppression. Cancer Res. 2000 Jun 15; 60(12):3123-6. PMID: 10866297.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    159. Xia W, Lau YK, Hu MC, Li L, Johnston DA, Sheng Sj, El-Naggar A, Hung MC. High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma. Oncogene. 2000 May 11; 19(20):2398-403. PMID: 10828881.
      Citations: 29     Fields:    Translation:HumansCells
    160. Lin SY, Xia W, Wang JC, Kwong KY, Spohn B, Wen Y, Pestell RG, Hung MC. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4262-6. PMID: 10759547.
      Citations: 302     Fields:    Translation:HumansCells
    161. Zhou BP, Hu MC, Miller SA, Yu Z, Xia W, Lin SY, Hung MC. HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway. J Biol Chem. 2000 Mar 17; 275(11):8027-31. PMID: 10713122.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    162. Xing X, Wang SC, Xia W, Zou Y, Shao R, Kwong KY, Yu Z, Zhang S, Miller S, Huang L, Hung MC. The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis. Nat Med. 2000 Feb; 6(2):189-95. PMID: 10655108.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    163. Xia W, Lau YK, Zhang HZ, Xiao FY, Johnston DA, Liu AR, Li L, Katz RL, Hung MC. Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members. Clin Cancer Res. 1999 Dec; 5(12):4164-74. PMID: 10632356.
      Citations: 74     Fields:    Translation:HumansCells
    164. Ueno NT, Xia W, Tucker SD, Zhang S, Lopez-Berestein G, Huang L, Hung MC. Issues in the development of gene therapy: preclinical experiments in E1A gene delivery. Oncol Rep. 1999 Mar-Apr; 6(2):257-62. PMID: 10022986.
      Citations:    Fields:    Translation:HumansCells
    165. Zhang L, Lau YK, Xia W, Hortobagyi GN, Hung MC. Tyrosine kinase inhibitor emodin suppresses growth of HER-2/neu-overexpressing breast cancer cells in athymic mice and sensitizes these cells to the inhibitory effect of paclitaxel. Clin Cancer Res. 1999 Feb; 5(2):343-53. PMID: 10037184.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    166. Deng J, Xia W, Hung MC. Adenovirus 5 E1A-mediated tumor suppression associated with E1A-mediated apoptosis in vivo. Oncogene. 1998 Oct 29; 17(17):2167-75. PMID: 9811448.
      Citations: 9     Fields:    Translation:AnimalsCells
    167. Liu B, Sun D, Xia W, Hung MC, Yu D. Cross-reactivity of C219 anti-p170(mdr-1) antibody with p185(c-erbB2) in breast cancer cells: cautions on evaluating p170(mdr-1) J Natl Cancer Inst. 1997 Oct 15; 89(20):1524-9. PMID: 9337349.
      Citations: 8     Fields:    Translation:HumansCells
    168. Xing X, Liu V, Xia W, Stephens LC, Huang L, Lopez-Berestein G, Hung MC. Safety studies of the intraperitoneal injection of E1A--liposome complex in mice. Gene Ther. 1997 Mar; 4(3):238-43. PMID: 9135737.
      Citations: 4     Fields:    Translation:AnimalsCells
    169. Chang JY, Xia W, Shao R, Sorgi F, Hortobagyi GN, Huang L, Hung MC. The tumor suppression activity of E1A in HER-2/neu-overexpressing breast cancer. Oncogene. 1997 Feb 06; 14(5):561-8. PMID: 9053854.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    170. Xia W, Lau YK, Zhang HZ, Liu AR, Li L, Kiyokawa N, Clayman GL, Katz RL, Hung MC. Strong correlation between c-erbB-2 overexpression and overall survival of patients with oral squamous cell carcinoma. Clin Cancer Res. 1997 Jan; 3(1):3-9. PMID: 9815530.
      Citations: 27     Fields:    Translation:HumansCells
    171. Chang JY, Xia W, Shao R, Hung MC. Inhibition of intratracheal lung cancer development by systemic delivery of E1A. Oncogene. 1996 Oct 03; 13(7):1405-12. PMID: 8875978.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    172. Yu D, Matin A, Xia W, Sorgi F, Huang L, Hung MC. Liposome-mediated in vivo E1A gene transfer suppressed dissemination of ovarian cancer cells that overexpress HER-2/neu. Oncogene. 1995 Oct 05; 11(7):1383-8. PMID: 7478560.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    173. Zhang Y, Yu D, Xia W, Hung MC. HER-2/neu-targeting cancer therapy via adenovirus-mediated E1A delivery in an animal model. Oncogene. 1995 May 18; 10(10):1947-54. PMID: 7761095.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    174. Dubinett SM, Callahan RJ, Xia WJ, Ahmad M, Strauss HW, Kradin RL. Cytokine administration alters the distribution of activated lymphocytes to the lung. Pathobiology. 1991; 59(6):372-7. PMID: 1930689.
      Citations:    Fields:    Translation:AnimalsCells
    175. Xia WY. [Immunologic reaction of cervical lymph nodes in relation to the prognosis of oral squamous cell carcinoma]. Zhonghua Kou Qiang Ke Za Zhi. 1980 Dec; 15(4):211-5. PMID: 6942992.
      Citations:    Fields:    Translation:Humans
    176. AKT1 inhibits epithelial-to-mesenchymal transition in breast cancer through phosphorylation-dependent twist1 degradation. Cancer Research. 76:1451-1462.
    177. GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers. Oncotarget. 7:57131-57144.
    178. Blocking metastasis. Cancer Biology and Therapy. 3:928.
    179. PFKFB3 potentially contributes to paclitaxel resistance in breast cancer cells through TLR4 activation by stimulating lactate production. Cellular and Molecular Biology. 62:119-125.
    180. S6k1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer. American Journal of Translational Research. 6:361-376.
    181. Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity. Nature Communications. 7.
    182. Deubiquitination and Stabilization of PD-L1 by CSN5. Cancer Cell. 30:925-939.
    183. Phosphorylation of ezh2 at t416 by cdk2 contributes to the malignancy of triple negative breast cancers. American Journal of Translational Research. 7:1009-1020.
    184. STK15/BTAK/aurora-A expression in ductal carcinoma in situ of the breast. Breast Cancer Research and Treatment. 69:250.
    185. Erratum. Cancer Research. 65:2045.
    186. Aurora A kinase activates YAP signaling in triple-negative breast cancer. Oncogene.
    187. Erratum. Nature Cell Biology. 13:1467.
    188. APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis (Journal of Clinical Investigation (2012) 122, 1 (419) DOI. Journal of Clinical Investigation. 122:419.
    189. Erratum. Nature Cell Biology. 13:1466.
    190. IκB Kinase Promotes Tumorigenesis through Inhibition of Forkhead FOXO3a (PII. Cell. 129:1427-1428.
    191. High level of STK-15 expression in primary breast tumors correlates with nuclear grade. Breast Cancer Research and Treatment. 69:266.
    192. EGFR signaling enhances aerobic glycolysis in triple-negative breast cancer cells to promote tumor growth and immune escape. Cancer Research. 76:1284-1296.
    193. Activation of keap1/nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. American Journal of Translational Research. 6:649-663.
    194. HER2-positive breast cancers make more CXCR4 which helps them invade and metastasize. Cancer Biology and Therapy. 3:1195-1196.
    195. PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response. Journal of Clinical Investigation. 125:4529-4543.
    196. Oncogenic functions of Gli1 in pancreatic adenocarcinoma are supported by its PRMT1-mediated methylation. Cancer Research. 76:7049-7058.
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