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WEIYA XIA

TitleAssistant Professor
InstitutionMD Anderson
DepartmentMolecular & Cellular Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang YN, Lee HH, Chou CK, Yang WH, Wei Y, Chen CT, Yao J, Hsu JL, Zhu C, Ying H, Ye Y, Wang WJ, Lim SO, Xia W, Ko HW, Liu X, Liu CG, Wu X, Wang H, Li D, Prakash LR, Katz MH, Kang Y, Kim M, Fleming JB, Fogelman D, Javle M, Maitra A, Hung MC. Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer. Cancer Cell. 2018 Apr 09; 33(4):752-769.e8. PMID: 29606349.
      View in: PubMed
    2. Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, Perillo EP, Dunn AK, Kuo CW, Khoo KH, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Huang TH, Sahin AA, Hortobagyi GN, Yoo SS, Hung MC. Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1. Cancer Cell. 2018 Feb 12; 33(2):187-201.e10. PMID: 29438695.
      View in: PubMed
    3. Wang S, Liang K, Hu Q, Li P, Song J, Yang Y, Yao J, Mangala LS, Li C, Yang W, Park PK, Hawke DH, Zhou J, Zhou Y, Xia W, Hung MC, Marks JR, Gallick GE, Lopez-Berestein G, Flores ER, Sood AK, Huang S, Yu D, Yang L, Lin C. JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. J Clin Invest. 2017 Dec 01; 127(12):4498-4515. PMID: 29130936.
      View in: PubMed
    4. Li CW, Lim SO, Xia W, Lee HH, Chan LC, Kuo CW, Khoo KH, Chang SS, Cha JH, Kim T, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Ding Q, Wang Y, Yao J, Lee CC, Wu HJ, Sahin AA, Allison JP, Yu D, Hortobagyi GN, Hung MC. Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity. Nat Commun. 2016; 7:12632. PMID: 27572267.
      View in: PubMed
    5. Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, Wang Y, Chou CK, Hsu JM, Lai YJ, LaBaff AM, Ding Q, Ko HW, Tsai FJ, Tsai CH, Hortobagyi GN, Hung MC. AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation. Cancer Res. 2016 Mar 15; 76(6):1451-62. PMID: 26759241; PMCID: PMC4794388 [Available on 03/15/17].
    6. Liao HW, Hsu JM, Xia W, Wang HL, Wang YN, Chang WC, Arold ST, Chou CK, Tsou PH, Yamaguchi H, Fang YF, Lee HJ, Lee HH, Tai SK, Yang MH, Morelli MP, Sen M, Ladbury JE, Chen CH, Grandis JR, Kopetz S, Hung MC. PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response. J Clin Invest. 2015 Dec; 125(12):4529-43. PMID: 26571401.
      View in: PubMed
    7. Jiang Y, Fu Y, Xing XP, Li M, Wang O, Xia WB, Meng XW. Zoledronic acid-induced hepatotoxicity relieved after subsequent infusions in a Chinese woman with glucocorticoid-induced osteoporosis. Eur J Med Res. 2015; 20:68. PMID: 26297149.
      View in: PubMed
    8. Zhou PR, Xu XJ, Zhang ZL, Liao EY, Chen DC, Liu J, Wu W, Jiang Y, Wang O, Xia WB, Xing XP, Xu L, Li M. SOST polymorphisms and response to alendronate treatment in postmenopausal Chinese women with osteoporosis. Pharmacogenomics. 2015; 16(10):1077-88. PMID: 26250343.
      View in: PubMed
    9. Yuan L, Chen L, Liao RX, Lin YY, Jiang Y, Wang O, Li M, Xing XP, Pang QQ, Jiajue R, Xia WB. A Common Mutation and a Novel Mutation in the HPGD Gene in Nine Patients with Primary Hypertrophic Osteoarthropathy. Calcif Tissue Int. 2015 Oct; 97(4):336-42. PMID: 26135126.
      View in: PubMed
    10. Yang CC, LaBaff A, Wei Y, Nie L, Xia W, Huo L, Yamaguchi H, Hsu YH, Hsu JL, Liu D, Lang J, Du Y, Lien HC, Li LY, Deng R, Chan LC, Yao J, Kleer CG, Hortobagyi GN, Hung MC. Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers. Am J Transl Res. 2015; 7(6):1009-20. PMID: 26279746.
      View in: PubMed
    11. Lee DF, Su J, Kim HS, Chang B, Papatsenko D, Zhao R, Yuan Y, Gingold J, Xia W, Darr H, Mirzayans R, Hung MC, Schaniel C, Lemischka IR. Modeling familial cancer with induced pluripotent stem cells. Cell. 2015 Apr 9; 161(2):240-54. PMID: 25860607.
      View in: PubMed
    12. Xu LJ, Jiang Y, Liao RX, Zhang HB, Mao JF, Chi Y, Li M, Wang O, Liu XQ, Liu ZY, Xing XP, Yu W, Xia WB. Low-dose adefovir dipivoxil may induce Fanconi syndrome: clinical characteristics and long-term follow-up for Chinese patients. Antivir Ther. 2015; 20(6):603-11. PMID: 25814481.
      View in: PubMed
    13. Huo L, Li CW, Huang TH, Lam YC, Xia W, Tu C, Chang WC, Hsu JL, Lee DF, Nie L, Yamaguchi H, Wang Y, Lang J, Li LY, Chen CH, Mishra L, Hung MC. Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. Am J Transl Res. 2014; 6(6):649-63. PMID: 25628777.
      View in: PubMed
    14. Thirumurthi U, Shen J, Xia W, LaBaff AM, Wei Y, Li CW, Chang WC, Chen CH, Lin HK, Yu D, Hung MC. MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer. Sci Signal. 2014; 7(336):ra71. PMID: 25074979.
      View in: PubMed
    15. Chou RH, Wang YN, Hsieh YH, Li LY, Xia W, Chang WC, Chang LC, Cheng CC, Lai CC, Hsu JL, Chang WJ, Chiang SY, Lee HJ, Liao HW, Chuang PH, Chen HY, Wang HL, Kuo SC, Chen CH, Yu YL, Hung MC. EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4. Dev Cell. 2014 Jul 28; 30(2):224-37. PMID: 25073158.
      View in: PubMed
    16. Khotskaya YB, Goverdhan A, Shen J, Ponz-Sarvise M, Chang SS, Hsu MC, Wei Y, Xia W, Yu D, Hung MC. S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer. Am J Transl Res. 2014; 6(4):361-76. PMID: 25075253.
      View in: PubMed
    17. Zhou PR, Liu HJ, Liao EY, Zhang ZL, Chen de C, Liu J, Wu W, Xing XP, Xia WB, Xu L, Li M. LRP5 polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis. Pharmacogenomics. 2014 Apr; 15(6):821-31. PMID: 24897288.
      View in: PubMed
    18. Kong J, Wang O, Nie M, Shi J, Jiang Y, Li M, Xia WB, Meng XW, Xing XP. [CDC73 gene mutation and parafibromin expression status of parathyroid carcinoma in Chinese]. Zhonghua Yi Xue Za Zhi. 2013 Nov 12; 93(42):3364-8. PMID: 24418033.
      View in: PubMed
    19. Zhao Z, Xia WB, Xing XP, Li M, Wang O, Jiang Y, Xu LJ, Li N. [Infantile hypophosphatasia due to mutations in the tissue-nonspecific alkaline phosphatase gene]. Zhonghua Nei Ke Za Zhi. 2013 Oct; 52(10):824-8. PMID: 24378058.
      View in: PubMed
    20. Wang X, Saso H, Iwamoto T, Xia W, Gong Y, Pusztai L, Woodward WA, Reuben JM, Warner SL, Bearss DJ, Hortobagyi GN, Hung MC, Ueno NT. TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase. Cancer Res. 2013 Nov 1; 73(21):6516-25. PMID: 24014597.
      View in: PubMed
    21. Saldana SM, Lee HH, Lowery FJ, Khotskaya YB, Xia W, Zhang C, Chang SS, Chou CK, Steeg PS, Yu D, Hung MC. Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis. PLoS One. 2013; 8(9):e73406. PMID: 24039934; PMCID: PMC3764163.
    22. Khotskaya YB, Beck BH, Hurst DR, Han Z, Xia W, Hung MC, Welch DR. Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix. Mol Carcinog. 2014 Dec; 53(12):1011-26. PMID: 24000122.
      View in: PubMed
    23. Huang TH, Huo L, Wang YN, Xia W, Wei Y, Chang SS, Chang WC, Fang YF, Chen CT, Lang JY, Tu C, Wang Y, Hsu MC, Kuo HP, Ko HW, Shen J, Lee HH, Lee PC, Wu Y, Chen CH, Hung MC. Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers. Cancer Cell. 2013 Jun 10; 23(6):796-810. PMID: 23764002; PMCID: PMC3703149.
    24. Shen J, Xia W, Khotskaya YB, Huo L, Nakanishi K, Lim SO, Du Y, Wang Y, Chang WC, Chen CH, Hsu JL, Wu Y, Lam YC, James BP, Liu X, Liu CG, Patel DJ, Hung MC. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature. 2013 May 16; 497(7449):383-7. PMID: 23636329.
      View in: PubMed
    25. Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev. 2013 Feb 1; 27(3):274-87. PMID: 23388826; PMCID: PMC3576513.
    26. Li S, Xue HD, Jiang Y, Xia WB, Jing HL, Chen LB, Sun F, Jin ZY. Comparison of whole body diffusion weighted magnetic resonance imaging and somatostatin receptor scintigraphy for oncogenic osteomalacia. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Oct; 34(5):437-42. PMID: 23134817.
      View in: PubMed
    27. Jiang Y, Xia WB, Xing XP, Silva BC, Li M, Wang O, Zhang HB, Li F, Jing HL, Zhong DR, Jin J, Gao P, Zhou L, Qi F, Yu W, Bilezikian JP, Meng XW. Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature. J Bone Miner Res. 2012 Sep; 27(9):1967-75. PMID: 22532501.
      View in: PubMed
    28. Wang O, Wang CY, Shi J, Nie M, Xia WB, Li M, Jiang Y, Guan H, Meng XW, Xing XP. Expression of Ki-67, galectin-3, fragile histidine triad, and parafibromin in malignant and benign parathyroid tumors. Chin Med J (Engl). 2012 Aug; 125(16):2895-901. PMID: 22932087.
      View in: PubMed
    29. Zhang D, Lu L, Yang HB, Li M, Sun H, Zeng ZP, Li XP, Xia WB, Xing XP. Exome sequencing identifies compound heterozygous PKHD1 mutations as a cause of autosomal recessive polycystic kidney disease. Chin Med J (Engl). 2012 Jul; 125(14):2482-6. PMID: 22882926.
      View in: PubMed
    30. Wang Y, Ding Q, Yen CJ, Xia W, Izzo JG, Lang JY, Li CW, Hsu JL, Miller SA, Wang X, Lee DF, Hsu JM, Huo L, Labaff AM, Liu D, Huang TH, Lai CC, Tsai FJ, Chang WC, Chen CH, Wu TT, Buttar NS, Wang KK, Wu Y, Wang H, Ajani J, Hung MC. The crosstalk of mTOR/S6K1 and Hedgehog pathways. Cancer Cell. 2012 Mar 20; 21(3):374-87. PMID: 22439934.
      View in: PubMed
    31. Li CW, Xia W, Huo L, Lim SO, Wu Y, Hsu JL, Chao CH, Yamaguchi H, Yang NK, Ding Q, Wang Y, Lai YJ, LaBaff AM, Wu TJ, Lin BR, Yang MH, Hortobagyi GN, Hung MC. Epithelial-mesenchymal transition induced by TNF-a requires NF-?B-mediated transcriptional upregulation of Twist1. Cancer Res. 2012 Mar 1; 72(5):1290-300. PMID: 22253230.
      View in: PubMed
    32. Xia WB, He SL, Xu L, Liu AM, Jiang Y, Li M, Wang O, Xing XP, Sun Y, Cummings SR. Rapidly increasing rates of hip fracture in Beijing, China. J Bone Miner Res. 2012 Jan; 27(1):125-9. PMID: 21956596.
      View in: PubMed
    33. Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, Dhar D, Karin M, Chen CH, Hung MC. IKKa activation of NOTCH links tumorigenesis via FOXA2 suppression. Mol Cell. 2012 Jan 27; 45(2):171-84. PMID: 22196886.
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    34. Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, Huo L, Cheng X, Chen YJ, Li CW, Jeng LB, Hsu JL, Li LY, Tan A, Curley SA, Ellis LM, Dubois RN, Hung MC. APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. J Clin Invest. 2011 Nov; 121(11):4526-36. PMID: 21985787; PMCID: PMC3204827.
    35. Li M, Xia WB, Xing XP, Yu W, Hu YY, Jiang Y, Wang O, Liu HJ, Han LW, Meng XW, Xu L. Benefit of infusions with ibandronate treatment in children with osteogenesis imperfecta. Chin Med J (Engl). 2011 Oct; 124(19):3049-53. PMID: 22040553.
      View in: PubMed
    36. Sun XF, Zhang HB, Li XP, Xia WB, Xing XP, Meng XW. [A case of adefovir dipivoxil induced hypophosphataemic osteomalacia and literature review]. Zhonghua Nei Ke Za Zhi. 2011 Sep; 50(9):754-7. PMID: 22176963.
      View in: PubMed
    37. Le XF, Mao W, He G, Claret FX, Xia W, Ahmed AA, Hung MC, Siddik ZH, Bast RC. The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells. J Natl Cancer Inst. 2011 Sep 21; 103(18):1403-22. PMID: 21813412.
      View in: PubMed
    38. Euhus D, Bu D, Xie XJ, Sarode V, Ashfaq R, Hunt K, Xia W, O'Shaughnessy J, Grant M, Arun B, Dooley W, Miller A, Flockhart D, Lewis C. Tamoxifen downregulates ets oncogene family members ETV4 and ETV5 in benign breast tissue: implications for durable risk reduction. Cancer Prev Res (Phila). 2011 Nov; 4(11):1852-62. PMID: 21778330; PMCID: PMC3208724.
    39. Chen CT, Yamaguchi H, Lee HJ, Du Y, Lee HH, Xia W, Yu WH, Hsu JL, Yen CJ, Sun HL, Wang Y, Yeh ET, Hortobagyi GN, Hung MC. Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase. Mol Cancer Ther. 2011 Aug; 10(8):1327-36. PMID: 21610170; PMCID: PMC3155219.
    40. Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, Yu WH, Rehman SK, Hsu JL, Lee HH, Liu M, Chen CT, Yu D, Hung MC. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol. 2011 Mar; 13(3):317-23. PMID: 21336307.
      View in: PubMed
    41. Chang CJ, Yang JY, Xia W, Chen CT, Xie X, Chao CH, Woodward WA, Hsu JM, Hortobagyi GN, Hung MC. EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-ß-catenin signaling. Cancer Cell. 2011 Jan 18; 19(1):86-100. PMID: 21215703.
      View in: PubMed
    42. Tsai WW, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S, Tsai CY, Shi X, Schwarzer D, Plunkett W, Aronow B, Gozani O, Fischle W, Hung MC, Patel DJ, Barton MC. TRIM24 links a non-canonical histone signature to breast cancer. Nature. 2010 Dec 16; 468(7326):927-32. PMID: 21164480; PMCID: PMC3058826.
    43. Cheng X, Xia W, Yang JY, Hsu JL, Chou CK, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of p21(CIP1/WAF1) in mammary epithelium accelerates mammary tumorigenesis and promotes lung metastasis. Biochem Biophys Res Commun. 2010 Dec 3; 403(1):103-7. PMID: 21040707.
      View in: PubMed
    44. Zhu Y, Zhang HB, Lu L, Li NS, Fu Y, Wang O, Xu LL, Jiang Y, Tong AL, Zhu HJ, Li W, Hu MM, Yu M, Mao JF, Yuan T, Li M, Xia WB, Xing XP. [Adrenal lesions in patients of multiple endocrine neoplasia type 1]. Zhonghua Yi Xue Za Zhi. 2010 Oct 19; 90(38):2689-92. PMID: 21162898.
      View in: PubMed
    45. Cheng X, Xia W, Yang JY, Hsu JL, Lang JY, Chou CK, Du Y, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of murine double minute 2 by Akt in mammary epithelium delays mammary involution and accelerates mammary tumorigenesis. Cancer Res. 2010 Oct 1; 70(19):7684-9. PMID: 20841468; PMCID: PMC2948588.
    46. Huo L, Wang YN, Xia W, Hsu SC, Lai CC, Li LY, Chang WC, Wang Y, Hsu MC, Yu YL, Huang TH, Ding Q, Chen CH, Tsai CH, Hung MC. RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16125-30. PMID: 20802156; PMCID: PMC2941329.
    47. Wang CY, Wang O, Nie M, Zhao DC, Xia WB, Li M, Guan H, Meng XW, Xing XP. [Clinical and molecular genetic analyses for a sporadic parathyroid carcinoma]. Zhonghua Yi Xue Za Zhi. 2010 Jun 22; 90(24):1694-7. PMID: 20979880.
      View in: PubMed
    48. Yang JY, Chang CJ, Xia W, Wang Y, Wong KK, Engelman JA, Du Y, Andreeff M, Hortobagyi GN, Hung MC. Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer. Cancer Res. 2010 Jun 1; 70(11):4709-18. PMID: 20484037.
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    49. Xia WB, Jiang Y, Li M, Xing XP, Wang O, Hu YY, Zhang HB, Liu HC, Meng XW, Zhou XY. Levels and dynamic changes of serum fibroblast growth factor 23 in hypophosphatemic rickets/osteomalacia. Chin Med J (Engl). 2010 May 5; 123(9):1158-62. PMID: 20529556.
      View in: PubMed
    50. Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, Xing G, Zhao Y, Lin CH, Tsai SF, Fidler IJ, Hung MC. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal. 2010; 3(108):ra9. PMID: 20145209.
      View in: PubMed
    51. Xia WJ, Ye X, Tian LW, Xu XZ, Chen YK, Luo GP, Bei CH, Deng J, Santoso S, Fu YS. Establishment of platelet donor registry improves the treatment of platelet transfusion refractoriness in Guangzhou region of China. Transfus Med. 2010 Aug 1; 20(4):269-74. PMID: 20136782.
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    52. Bui-Nguyen TM, Pakala SB, Sirigiri RD, Xia W, Hung MC, Sarin SK, Kumar V, Slagle BL, Kumar R. NF-kappaB signaling mediates the induction of MTA1 by hepatitis B virus transactivator protein HBx. Oncogene. 2010 Feb 25; 29(8):1179-89. PMID: 20010875; PMCID: PMC3621706.
    53. Andre F, Xia W, Conforti R, Wei Y, Boulet T, Tomasic G, Spielmann M, Zoubir M, Berrada N, Arriagada R, Hortobagyi GN, Hung MC, Pusztai L, Delaloge S, Michiels S, Cristofanilli M. CXCR4 expression in early breast cancer and risk of distant recurrence. Oncologist. 2009 Dec; 14(12):1182-8. PMID: 19939894.
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    54. Li M, Xing XP, Zhang ZL, Liu JL, Zhang ZL, Liu DG, Xia WB, Meng XW. Infusion of ibandronate once every 3 months effectively decreases bone resorption markers and increases bone mineral density in Chinese postmenopausal osteoporotic women: a 1-year study. J Bone Miner Metab. 2010 May; 28(3):299-305. PMID: 19855926.
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    55. Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Chen CT, Huo L, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, Chang YH, Tsai SF, Li LY, Hung MC. KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Mol Cell. 2009 Oct 9; 36(1):131-40. PMID: 19818716; PMCID: PMC2770835.
    56. Kuo HP, Lee DF, Xia W, Wei Y, Hung MC. TNFalpha induces HIF-1alpha expression through activation of IKKbeta. Biochem Biophys Res Commun. 2009 Nov 27; 389(4):640-4. PMID: 19766100.
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    57. Han GY, Wang O, Xing XP, Meng XW, Lian XL, Guan H, Ye W, Xia WB, Li M, Jiang Y, Hu YY, Liu HC, Cui QC. [The efficacy and safety of intravenous bisphosphonates in the treatment of primary hyperparathyroidism complicated by hypercalcemia crisis]. Zhonghua Nei Ke Za Zhi. 2009 Sep; 48(9):729-33. PMID: 20079207.
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    58. Kuo HP, Lee DF, Xia W, Lai CC, Li LY, Hung MC. Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation. Biochem Biophys Res Commun. 2009 Nov 6; 389(1):156-61. PMID: 19716809; PMCID: PMC2753275.
    59. Xie X, Hsu JL, Choi MG, Xia W, Yamaguchi H, Chen CT, Trinh BQ, Lu Z, Ueno NT, Wolf JK, Bast RC, Hung MC. A novel hTERT promoter-driven E1A therapeutic for ovarian cancer. Mol Cancer Ther. 2009 Aug; 8(8):2375-82. PMID: 19671744; PMCID: PMC2759534.
    60. Xia W, Wei Y, Du Y, Liu J, Chang B, Yu YL, Huo LF, Miller S, Hung MC. Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer. Mol Carcinog. 2009 Jul; 48(7):610-7. PMID: 19058255; PMCID: PMC2718429.
    61. He XD, Xia WB, Xing XP, Li M, Jiang Y, Wang O, Xu LL, Xu JP. [Clinical features of pregnancy and lactation-associated osteoporosis: analysis of 4 cases]. Zhonghua Yi Xue Za Zhi. 2009 Apr 14; 89(14):983-5. PMID: 19671313.
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    62. Xia WB, Zhang ZL, Wang HF, Meng XW, Zhang Y, Zhu GY, Xing XP, Liu JL, Wang LH, Jiang Y, Weng SF, Xu T, Hu YY, Yu W, Tian JP. The efficacy and safety of calcitriol and/or Caltrate D in elderly Chinese women with low bone mass. Acta Pharmacol Sin. 2009 Mar; 30(3):372-8. PMID: 19262561.
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    63. Wang O, Xing XP, Meng XW, Xia WB, Li M, Jiang Y, Hu YY, Liu HC. Treatment of hypocalcemia caused by hypoparathyroidism or pseudohypoparathyroidism with domestic-made calcitriol: a prospective and self-controlled clinical trial. Chin Med J (Engl). 2009 Feb 5; 122(3):279-83. PMID: 19236804.
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    64. Wei Y, Xia W, Zhang Z, Liu J, Wang H, Adsay NV, Albarracin C, Yu D, Abbruzzese JL, Mills GB, Bast RC, Hortobagyi GN, Hung MC. Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers. Mol Carcinog. 2008 Sep; 47(9):701-6. PMID: 18176935; PMCID: PMC2580832.
    65. Ding Q, Huo L, Yang JY, Xia W, Wei Y, Liao Y, Chang CJ, Yang Y, Lai CC, Lee DF, Yen CJ, Chen YJ, Hsu JM, Kuo HP, Lin CY, Tsai FJ, Li LY, Tsai CH, Hung MC. Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Res. 2008 Aug 1; 68(15):6109-17. PMID: 18676833; PMCID: PMC2676572.
    66. Hung LY, Tseng JT, Lee YC, Xia W, Wang YN, Wu ML, Chuang YH, Lai CH, Chang WC. Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression. Nucleic Acids Res. 2008 Aug; 36(13):4337-51. PMID: 18586824.
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    67. Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat Cell Biol. 2008 Feb; 10(2):138-48. PMID: 18204439; PMCID: PMC2376808.
    68. Lo HW, Hsu SC, Xia W, Cao X, Shih JY, Wei Y, Abbruzzese JL, Hortobagyi GN, Hung MC. Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression. Cancer Res. 2007 Oct 1; 67(19):9066-76. PMID: 17909010; PMCID: PMC2570961.
    69. Wang X, Zheng M, Liu G, Xia W, McKeown-Longo PJ, Hung MC, Zhao J. Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Cancer Res. 2007 Aug 1; 67(15):7184-93. PMID: 17671186.
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    70. Xie X, Xia W, Li Z, Kuo HP, Liu Y, Li Z, Ding Q, Zhang S, Spohn B, Yang Y, Wei Y, Lang JY, Evans DB, Chiao PJ, Abbruzzese JL, Hung MC. Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. Cancer Cell. 2007 Jul; 12(1):52-65. PMID: 17613436.
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    71. Jiang Y, Meng XW, Lu ZL, Xia WB, Xing XP, Li M, Wang O, Yu W, Tian JP. [Bone loss is more severe in younger Cushing's syndrome women than in older ones: comparison of bone mineral density between Cushing's syndrome and healthy women]. Zhonghua Yi Xue Za Zhi. 2007 Jun 26; 87(24):1695-7. PMID: 17825152.
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    72. Ding Q, He X, Xia W, Hsu JM, Chen CT, Li LY, Lee DF, Yang JY, Xie X, Liu JC, Hung MC. Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer. Cancer Res. 2007 May 15; 67(10):4564-71. PMID: 17495324.
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    81. Yu Z, Xia W, Wang HY, Wang SC, Pan Y, Kwong KY, Hortobagyi GN, Hung MC. Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1. Mol Carcinog. 2006 Sep; 45(9):667-75. PMID: 16652376.
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    93. Li YM, Pan Y, Wei Y, Cheng X, Zhou BP, Tan M, Zhou X, Xia W, Hortobagyi GN, Yu D, Hung MC. Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. Cancer Cell. 2004 Nov; 6(5):459-69. PMID: 15542430.
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    96. Wang SC, Lien HC, Xia W, Chen IF, Lo HW, Wang Z, Ali-Seyed M, Lee DF, Bartholomeusz G, Ou-Yang F, Giri DK, Hung MC. Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2. Cancer Cell. 2004 Sep; 6(3):251-61. PMID: 15380516.
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