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ZEEV ESTROV
Title
Professor
Institution
MD Anderson
Department
Leukemia
Address
1400 Holcombe Blvd
Houston TX 77030-4008
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
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Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Masarova L,
Bose P
,
Pemmaraju N
,
Kantarjian H
,
Estrov Z
,
Verstovsek S
. MPN-354 Characteristics of Patients With Myelofibrosis Taking Ruxolitinib for 3 or More Years. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S334.
PMID:
36164003
.
Citations:
Masarova L,
Bose P
,
Pemmaraju N
,
Kantarjian H
,
Estrov Z
,
Verstovsek S
. MPN-355 Patients With Prefibrotic Myelofibrosis and Inferior Outcome, a Single-Center Analysis. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S334-S335.
PMID:
36164004
.
Citations:
Cherng HJ, Khwaja R, Kanagal-Shamanna R, Tang G,
Burger J
, Thompson P,
Ferrajoli A
,
Estrov Z
, Sasaki K, Sampath D, Wang X,
Kantarjian H
, Keating M,
Wierda WG
,
Jain N
. TP53-altered chronic lymphocytic leukemia treated with firstline Bruton's tyrosine kinase inhibitor-based therapy: A retrospective analysis. Am J Hematol. 2022 08; 97(8):1005-1012.
PMID:
35567779
; PMCID:
PMC9354943
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Rozovski U, Veletic I, Harris DM, Li P, Liu Z, Jain P, Manshouri T,
Ferrajoli A
,
Burger JA
,
Bose P
, Thompson PA,
Jain N
,
Wierda WG
,
Verstovsek S
, Keating MJ,
Estrov Z
. STAT3 Activates the Pentraxin 3 Gene in Chronic Lymphocytic Leukemia Cells. J Immunol. 2022 06 15; 208(12):2847-2855.
PMID:
35595309
; PMCID:
PMC9308680
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Manshouri T, Veletic I, Li P, Yin CC,
Post SM
,
Verstovsek S
,
Estrov Z
. GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes. Cell Death Dis. 2022 May 20; 13(5):481.
PMID:
35595725
; PMCID:
PMC9122946
.
Citations:
Fields:
Cel
Cell Biology
Int
Internal Medicine
Translation:
Humans
Animals
Short NJ,
Borthakur G
,
Pemmaraju N
,
Dinardo CD
,
Kadia TM
,
Jabbour E
,
Konopleva M
, Macaron W,
Ning J
, Ma J, Pierce S,
Alvarado Y
, Sasaki K,
Takahashi K
,
Estrov Z
, Masarova L, Issa GC, Montalban-Bravo G,
Andreeff M
,
Burger JA
, Miller D, Alexander L,
Naing A
,
Garcia-Manero G
, Ravandi F,
Daver N
. A multi-arm phase Ib/II study designed for rapid, parallel evaluation of novel immunotherapy combinations in relapsed/refractory acute myeloid leukemia. Leuk Lymphoma. 2022 09; 63(9):2161-2170.
PMID:
35442137
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Vaca AM, Ioannou N, Sivina M, Vlachonikola E, Clise-Dwyer K, Kim E, Li D,
Ma Q
,
Ferrajoli A
,
Estrov Z
,
Wierda WG
, Patten PEM, Ramsay AG,
Burger JA
. Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures. Leukemia. 2022 05; 36(5):1324-1335.
PMID:
35149845
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Masarova L,
Bose P
,
Pemmaraju N
,
Daver NG
, Sasaki K, Chifotides HT, Zhou L,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Improved survival of patients with myelofibrosis in the last decade: Single-center experience. Cancer. 2022 04 15; 128(8):1658-1665.
PMID:
35077575
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Veletic I, Prijic S, Manshouri T, Nogueras-Gonzalez GM,
Verstovsek S
,
Estrov Z
. Altered T-cell subset repertoire affects treatment outcome of patients with myelofibrosis. Haematologica. 2021 09 01; 106(9):2384-2396.
PMID:
32732359
; PMCID:
PMC8409049
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
Pemmaraju N
,
Carter BZ
,
Bose P
,
Jain N
,
Kadia TM
,
Garcia-Manero G
,
Bueso-Ramos CE
,
DiNardo CD
, Bledsoe S,
Daver NG
,
Popat U
,
Konopleva MY
, Zhou L, Pierce S,
Estrov ZE
,
Borthakur GM
,
Ohanian M
, Qiao W, Masarova L, Wang X, Mak PY, Cortes J,
Jabbour E
,
Verstovsek S
. Final results of a phase 2 clinical trial of LCL161, an oral SMAC mimetic for patients with myelofibrosis. Blood Adv. 2021 08 24; 5(16):3163-3173.
PMID:
34424319
; PMCID:
PMC8405193
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Jain N
, Keating M, Thompson P,
Ferrajoli A
,
Burger JA
,
Borthakur G
,
Takahashi K
,
Estrov Z
, Sasaki K,
Fowler N
,
Kadia T
,
Konopleva M
,
Alvarado Y
, Yilmaz M,
DiNardo C
,
Bose P
,
Ohanian M
,
Pemmaraju N
,
Jabbour E
, Kanagal-Shamanna R, Patel K, Wang W,
Jorgensen J
, Wang SA,
Garg N
, Wang X, Wei C, Cruz N, Ayala A, Plunkett W,
Kantarjian H
,
Gandhi V
,
Wierda WG
. Ibrutinib Plus Venetoclax for First-line Treatment of Chronic Lymphocytic Leukemia: A Nonrandomized Phase 2 Trial. JAMA Oncol. 2021 Aug 01; 7(8):1213-1219.
PMID:
34110383
; PMCID:
PMC8193546
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Swaminathan M,
Kantarjian HM
, Levis M, Guerra V,
Borthakur G
,
Alvarado Y
,
DiNardo CD
,
Kadia T
,
Garcia-Manero G
,
Ohanian M
,
Daver N
,
Konopleva M
,
Pemmaraju N
,
Ferrajoli A
,
Andreeff M
,
Jain N
,
Estrov Z
,
Jabbour EJ
,
Wierda WG
, Pierce S, Pinsoy MR, Xiao L, Ravandi F,
Cortes JE
. A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome. Haematologica. 2021 08 01; 106(8):2121-2130.
PMID:
33853292
; PMCID:
PMC8327731
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kadia TM
, Ravandi F,
Borthakur G
,
Konopleva M
,
DiNardo CD
,
Daver N
,
Pemmaraju N
, Kanagal-Shamanna R, Wang X, Huang X, Pierce S, Rausch C,
Burger J
,
Ferrajoli A
,
Jain N
,
Popat U
,
Estrov Z
,
Verstovsek S
,
Jabbour E
,
Garcia-Manero G
,
Kantarjian H
. Long-term results of low-intensity chemotherapy with clofarabine or cladribine combined with low-dose cytarabine alternating with decitabine in older patients with newly diagnosed acute myeloid leukemia. Am J Hematol. 2021 08 01; 96(8):914-924.
PMID:
33901324
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Jain N
, Thompson P,
Burger J
,
Ferrajoli A
,
Takahashi K
,
Estrov Z
,
Borthakur G
,
Bose P
,
Kadia T
,
Pemmaraju N
, Sasaki K,
Konopleva M
,
Jabbour E
,
Garg N
, Wang X, Kanagal-Shamanna R, Patel K, Wang W,
Jorgensen J
, Wang S, Lopez W, Ayala A, Plunkett W,
Gandhi V
,
Kantarjian H
, O'Brien S, Keating M,
Wierda WG
. Ibrutinib, fludarabine, cyclophosphamide, and obinutuzumab (iFCG) regimen for chronic lymphocytic leukemia (CLL) with mutated IGHV and without TP53 aberrations. Leukemia. 2021 12; 35(12):3421-3429.
PMID:
34007049
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Bose P
, McCue D, Wurster S, Wiederhold NP,
Konopleva M
,
Kadia TM
,
Borthakur G
, Ravandi F, Masarova L,
Takahashi K
,
Estrov Z
, Yilmaz M,
Daver N
,
Pemmaraju N
,
Naqvi K
, Rausch CR, Marx KR, Qiao W, Huang X, Bivins CA, Pierce SA,
Kantarjian HM
,
Kontoyiannis DP
. Isavuconazole as Primary Antifungal Prophylaxis in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome: An Open-label, Prospective, Phase 2 Study. Clin Infect Dis. 2021 05 18; 72(10):1755-1763.
PMID:
32236406
; PMCID:
PMC8130026
.
Citations:
10
Fields:
Com
Communicable Diseases
Translation:
Humans
CT
Clinical Trials
Cherng HJ, Jammal N, Paul S, Wang X, Sasaki K, Thompson P,
Burger J
,
Ferrajoli A
,
Estrov Z
, O'Brien S, Keating M,
Wierda WG
,
Jain N
. Clinical and molecular characteristics and treatment patterns of adolescent and young adult patients with chronic lymphocytic leukaemia. Br J Haematol. 2021 07; 194(1):61-68.
PMID:
33973230
; PMCID:
PMC9284944
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Montalban-Bravo G, Kanagal-Shamanna R, Sasaki K, Masarova L,
Naqvi K
,
Jabbour E
,
DiNardo CD
,
Takahashi K
,
Konopleva M
,
Pemmaraju N
,
Kadia TM
, Ravandi F,
Daver N
,
Borthakur G
,
Estrov Z
,
Khoury JD
,
Loghavi S
, Soltysiak KA, Pierce S,
Bueso-Ramos C
,
Patel KP
,
Verstovsek S
,
Kantarjian HM
,
Bose P
,
Garcia-Manero G
. Clinicopathologic correlates and natural history of atypical chronic myeloid leukemia. Cancer. 2021 09 01; 127(17):3113-3124.
PMID:
33914911
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Masarova L,
DiNardo CD
,
Bose P
,
Pemmaraju N
,
Daver NG
,
Kadia TM
, Chifotides HT, Zhou L,
Borthakur G
,
Estrov Z
,
Konopleva M
,
Verstovsek S
. Single-center experience with venetoclax combinations in patients with newly diagnosed and relapsed AML evolving from MPNs. Blood Adv. 2021 04 27; 5(8):2156-2164.
PMID:
33885751
; PMCID:
PMC8095138
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Montalban-Bravo G, Hammond D,
DiNardo CD
,
Konopleva M
,
Borthakur G
, Short NJ, Ramos-Perez J, Guerra V, Kanagal-Shamanna R,
Naqvi K
, Sasaki K,
Jabbour E
,
Pemmaraju N
,
Kadia TM
, Ravandi F,
Daver N
,
Estrov Z
, Pierce S,
Kantarjian H
,
Garcia-Manero G
. Activity of venetoclax-based therapy in chronic myelomonocytic leukemia. Leukemia. 2021 05; 35(5):1494-1499.
PMID:
33846541
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Rozovski U, Harris DM, Li P, Liu Z, Jain P, Manshouri T, Veletic I,
Ferrajoli A
,
Bose P
, Thompson P,
Jain N
,
Verstovsek S
,
Wierda W
, Keating MJ,
Estrov Z
. STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells. Oncotarget. 2021 Mar 02; 12(5):401-411.
PMID:
33747356
; PMCID:
PMC7939524
.
Citations:
3
Fields:
Neo
Neoplasms
Abou Dalle I,
Kantarjian HM
, Ravandi F,
Daver N
, Wang X,
Jabbour E
,
Estrov Z
,
DiNardo CD
,
Pemmaraju N
,
Ferrajoli A
,
Jain N
, Wang SA, Jammal N,
Borthakur G
,
Naqvi K
, Pelletier S, Pierce S,
Andreeff M
,
Garcia-Manero G
,
Cortes JE
,
Kadia TM
. Phase 2 study of lenalidomide maintenance for patients with high-risk acute myeloid leukemia in remission. Cancer. 2021 06 01; 127(11):1894-1900.
PMID:
33449377
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L,
Bose P
,
Pemmaraju N
,
Daver N
, Zhou L, Pierce S,
Kantarjian H
,
Estrov Z
,
Verstovsek S
. Clinical Significance of Bone Marrow Blast Percentage in Patients With Myelofibrosis and the Effect of Ruxolitinib Therapy. Clin Lymphoma Myeloma Leuk. 2021 05; 21(5):318-327.e6.
PMID:
33551345
; PMCID:
PMC8849582
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Montalban-Bravo G, Kanagal-Shamanna R, Guerra V, Ramos-Perez J, Hammond D, Shilpa P,
Naqvi K
, Sasaki K,
Jabbour E
,
DiNardo C
,
Takahashi K
,
Konopleva M
,
Pemmaraju N
,
Kadia T
, Ravandi F,
Daver N
,
Borthakur G
,
Estrov Z
,
Khoury JD
,
Loghavi S
, Pierce S,
Bueso-Ramos C
, Patel K,
Kantarjian H
,
Garcia-Manero G
. Clinical outcomes and influence of mutation clonal dominance in oligomonocytic and classical chronic myelomonocytic leukemia. Am J Hematol. 2021 02 01; 96(2):E50-E53.
PMID:
33156969
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Sivina M, Xiao L, Kim E, Vaca A, Chen SS, Keating MJ,
Ferrajoli A
,
Estrov Z
,
Jain N
,
Wierda WG
, Huang X, Chiorazzi N,
Burger JA
. CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia. Leukemia. 2021 06; 35(6):1610-1620.
PMID:
33087831
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Yilmaz M,
Kantarjian HM
, Toruner G, Yin CC, Kanagal-Shamanna R,
Cortes JE
, Issa G, Short NJ,
Khoury JD
,
Garcia-Manero G
, Ravandi F,
Kadia T
,
Konopleva M
,
Wierda WG
,
Jain N
,
Estrov Z
, Sasaki K, Pierce S, O'Brien SM,
Jabbour EJ
. Translocation t(1;19)(q23;p13) in adult acute lymphoblastic leukemia - a distinct subtype with favorable prognosis. Leuk Lymphoma. 2021 01; 62(1):224-228.
PMID:
32955970
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
DiNardo CD
, Maiti A, Rausch CR,
Pemmaraju N
,
Naqvi K
,
Daver NG
,
Kadia TM
,
Borthakur G
,
Ohanian M
,
Alvarado Y
, Issa GC, Montalban-Bravo G, Short NJ, Yilmaz M,
Bose P
,
Jabbour EJ
,
Takahashi K
,
Burger JA
,
Garcia-Manero G
,
Jain N
,
Kornblau SM
, Thompson PA,
Estrov Z
, Masarova L, Sasaki K,
Verstovsek S
,
Ferrajoli A
, Weirda WG, Wang SA,
Konoplev S
, Chen Z, Pierce SA,
Ning J
, Qiao W, Ravandi F,
Andreeff M
, Welch JS,
Kantarjian HM
,
Konopleva MY
. 10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial. Lancet Haematol. 2020 Oct; 7(10):e724-e736.
PMID:
32896301
; PMCID:
PMC7549397
.
Citations:
62
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Abaza Y,
Kantarjian H
, Alwash Y,
Borthakur G
,
Champlin R
,
Kadia T
,
Garcia-Manero G
,
Daver N
, Ravandi F,
Verstovsek S
,
Burger J
,
Estrov Z
,
Ohanian M
, Lim M,
Pemmaraju N
,
Jabbour E
, Cortes J. Phase I/II study of dasatinib in combination with decitabine in patients with accelerated or blast phase chronic myeloid leukemia. Am J Hematol. 2020 11; 95(11):1288-1295.
PMID:
32681739
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Masarova L,
Bose P
,
Pemmaraju N
,
Daver NG
, Zhou L, Pierce S, Sasaki K,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Prognostic value of blasts in peripheral blood in myelofibrosis in the ruxolitinib era. Cancer. 2020 10 01; 126(19):4322-4331.
PMID:
32697338
; PMCID:
PMC7875207
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Issa GC,
Kantarjian HM
, Xiao L,
Ning J
,
Alvarado Y
,
Borthakur G
,
Daver N
,
DiNardo CD
,
Jabbour E
,
Bose P
,
Jain N
,
Kadia TM
,
Naqvi K
,
Pemmaraju N
,
Takahashi K
,
Verstovsek S
, Andreeff M,
Kornblau SM
,
Estrov Z
,
Ferrajoli A
,
Garcia-Manero G
,
Ohanian M
,
Wierda WG
, Ravandi F,
Cortes JE
. Phase II trial of CPX-351 in patients with acute myeloid leukemia at high risk for induction mortality. Leukemia. 2020 11; 34(11):2914-2924.
PMID:
32546726
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Short NJ,
Patel KP
, Albitar M, Franquiz M,
Luthra R
, Kanagal-Shamanna R, Wang F, Assi R, Montalban-Bravo G, Matthews J, Ma W,
Loghavi S
,
Takahashi K
, Issa GC,
Kornblau SM
,
Jabbour E
,
Garcia-Manero G
,
Kantarjian HM
,
Estrov Z
, Ravandi F. Targeted next-generation sequencing of circulating cell-free DNA vs bone marrow in patients with acute myeloid leukemia. Blood Adv. 2020 04 28; 4(8):1670-1677.
PMID:
32324887
; PMCID:
PMC7189293
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Hu Z, Wang W,
Thakral B
, Chen Z,
Estrov Z
,
Bueso-Ramos CE
,
Verstovsek S
, Medeiros LJ, Wang SA. Lymphocytic variant of hypereosinophilic syndrome: A report of seven cases from a single institution. Cytometry B Clin Cytom. 2021 05; 100(3):352-360.
PMID:
32157815
.
Citations:
1
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Bose P
,
Verstovsek S
,
Cortes JE
, Tse S, Gasior Y,
Jain N
,
Jabbour EJ
,
Estrov Z
,
Alvarado Y
,
DiNardo CD
,
Pemmaraju N
,
Kornblau SM
,
Kadia TM
,
Daver NG
,
Naqvi K
, Short NJ, Masarova L, Villareal J, Pierce SA, Nogueras-Gonzalez G, Huang X,
Garcia-Manero G
,
Kantarjian HM
, Ravandi F. A phase 1/2 study of ruxolitinib and decitabine in patients with post-myeloproliferative neoplasm acute myeloid leukemia. Leukemia. 2020 09; 34(9):2489-2492.
PMID:
32099037
.
Citations:
13
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Strati P,
Schlette EJ
, Solis Soto LM, Duenas DE, Sivina M, Kim E, Keating MJ,
Wierda WG
,
Ferrajoli A
,
Kantarjian H
,
Estrov Z
,
Jain N
, Thompson PA,
Wistuba II
,
Burger JA
. Achieving complete remission in CLL patients treated with ibrutinib: clinical significance and predictive factors. Blood. 2020 02 13; 135(7):510-513.
PMID:
31895947
; PMCID:
PMC7019190
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Maiti A,
Cortes JE
,
Patel KP
, Masarova L,
Borthakur G
, Ravandi F,
Verstovsek S
,
Ferrajoli A
,
Estrov Z
,
Garcia-Manero G
,
Kadia TM
, Skinner J, Poku R, DellaSala S,
Luthra R
,
Jabbour EJ
, O'Brien S,
Kantarjian HM
, Nogueras-Gonz?lez GM. Long-term results of frontline dasatinib in chronic myeloid leukemia. Cancer. 2020 04 01; 126(7):1502-1511.
PMID:
31999839
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L,
Cortes JE
,
Patel KP
, O'Brien S, Nogueras-Gonzalez GM,
Konopleva M
,
Verstovsek S
,
Garcia-Manero G
,
Ferrajoli A
,
Kadia TM
,
Ravandi-Kashani F
,
Borthakur G
, DellaSala S,
Estrov Z
,
Jabbour EJ
,
Kantarjian HM
. Long-term results of a phase 2 trial of nilotinib 400?mg twice daily in newly diagnosed patients with chronic-phase chronic myeloid leukemia. Cancer. 2020 04 01; 126(7):1448-1459.
PMID:
31999850
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Fuentes-Mattei E
, Bayraktar R, Manshouri T, Silva AM,
Ivan C
, Gulei D, Fabris L, Soares do Amaral N, Mur P, Perez C, Torres-Claudio E, Dragomir MP, Badillo-Perez A, Knutsen E, Narayanan P, Golfman L, Shimizu M, Zhang X, Zhao W, Ho WT, Estecio MR,
Bartholomeusz G
, Tomuleasa C, Berindan-Neagoe I, Zweidler-McKay PA,
Estrov Z
, Zhao ZJ,
Verstovsek S
,
Calin GA
, Redis RS. miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2. JCI Insight. 2020 01 16; 5(1).
PMID:
31941838
; PMCID:
PMC7030823
.
Citations:
9
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Kim E, Ten Hacken E, Sivina M, Clarke A, Thompson PA,
Jain N
,
Ferrajoli A
,
Estrov Z
, Keating MJ,
Wierda WG
,
Bhalla KN
,
Burger JA
. The BET inhibitor GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment. Leukemia. 2020 06; 34(6):1588-1598.
PMID:
31862959
; PMCID:
PMC7272263
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Thompson PA, Srivastava J, Peterson C, Strati P,
Jorgensen JL
, Hether T, Keating MJ, O'Brien SM,
Ferrajoli A
,
Burger JA
,
Estrov Z
,
Jain N
,
Wierda WG
. Minimal residual disease undetectable by next-generation sequencing predicts improved outcome in CLL after chemoimmunotherapy. Blood. 2019 11 28; 134(22):1951-1959.
PMID:
31537528
; PMCID:
PMC6887113
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Yilmaz M,
Kantarjian H
, Wang X,
Khoury JD
, Ravandi F,
Jorgensen J
, Short NJ,
Loghavi S
, Cortes J,
Garcia-Manero G
,
Kadia T
, Sasaki K,
Konopleva M
,
Takahashi K
,
Wierda W
,
Jain N
,
Verstovsek S
,
Estrov Z
,
Bose P
, Pierce S, Garris R, O'Brien S,
Jabbour E
. The early achievement of measurable residual disease negativity in the treatment of adults with Philadelphia-negative B-cell acute lymphoblastic leukemia is a strong predictor for survival. Am J Hematol. 2020 02; 95(2):144-150.
PMID:
31682008
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Rozovski U, Harris DM, Li P, Liu Z, Jain P,
Ferrajoli A
,
Burger JA
,
Bose P
, Thompson PA,
Jain N
,
Wierda WG
, Uziel O, Keating MJ,
Estrov Z
. STAT3-Induced Wnt5a Provides Chronic Lymphocytic Leukemia Cells with Survival Advantage. J Immunol. 2019 12 01; 203(11):3078-3085.
PMID:
31645416
; PMCID:
PMC6864283
.
Citations:
9
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Manshouri T,
Verstovsek S
, Harris DM, Veletic I, Zhang X,
Post SM
,
Bueso-Ramos CE
,
Estrov Z
. Primary myelofibrosis marrow-derived CD14+/CD34- monocytes induce myelofibrosis-like phenotype in immunodeficient mice and give rise to megakaryocytes. PLoS One. 2019; 14(9):e0222912.
PMID:
31569199
; PMCID:
PMC6768666
.
Citations:
6
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Naqvi K
,
Jabbour E
, Skinner J, Anderson K, Dellasala S, Yilmaz M,
Ferrajoli A
,
Bose P
, Thompson P,
Alvarado Y
,
Jain N
,
Takahashi K
,
Burger J
,
Estrov Z
,
Borthakur G
,
Pemmaraju N
, Paul S, Cortes J,
Kantarjian HM
. Long-term follow-up of lower dose dasatinib (50?mg daily) as frontline therapy in newly diagnosed chronic-phase chronic myeloid leukemia. Cancer. 2020 01 01; 126(1):67-75.
PMID:
31553487
; PMCID:
PMC8529949
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Abou Dalle I,
Kantarjian H
,
Burger J
,
Estrov Z
,
Ohanian M
,
Verstovsek S
, Ravandi F,
Borthakur G
,
Garcia-Manero G
,
Jabbour E
, Cortes J. Efficacy and safety of generic imatinib after switching from original imatinib in patients treated for chronic myeloid leukemia in the United States. Cancer Med. 2019 11; 8(15):6559-6565.
PMID:
31502383
; PMCID:
PMC6825993
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Ravandi F, Assi R,
Daver N
,
Benton CB
,
Kadia T
, Thompson PA,
Borthakur G
,
Alvarado Y
,
Jabbour EJ
,
Konopleva M
,
Takahashi K
,
Kornblau S
,
DiNardo CD
,
Estrov Z
, Flores W, Basu S,
Allison J
,
Sharma P
, Pierce S, Pike A,
Cortes JE
,
Garcia-Manero G
,
Kantarjian HM
. Idarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study. Lancet Haematol. 2019 Sep; 6(9):e480-e488.
PMID:
31400961
; PMCID:
PMC6778960
.
Citations:
31
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Strati P, Wang F, Tambaro FP, Thompson PA,
Burger JA
,
Jain N
,
Ferrajoli A
,
Bose P
,
Estrov Z
, Keating MJ,
Futreal A
,
Takahashi K
,
Wierda WG
. The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype. Br J Haematol. 2019 10; 187(1):e1-e4.
PMID:
31344256
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Hu B,
Patel KP
, Chen HC, Wang X,
Luthra R
,
Routbort MJ
, Kanagal-Shamanna R, Medeiros LJ, Yin CC,
Zuo Z
,
Ok CY
,
Loghavi S
, Tang G, Tambaro FP, Thompson P, Burger J,
Jain N
,
Ferrajoli A
,
Bose P
,
Estrov Z
, Keating M,
Wierda WG
. Association of gene mutations with time-to-first treatment in 384 treatment-naive chronic lymphocytic leukaemia patients. Br J Haematol. 2019 11; 187(3):307-318.
PMID:
31243771
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Jain N
, Keating M, Thompson P,
Ferrajoli A
, Burger J,
Borthakur G
,
Takahashi K
,
Estrov Z
,
Fowler N
,
Kadia T
,
Konopleva M
,
Alvarado Y
, Yilmaz M,
DiNardo C
,
Bose P
,
Ohanian M
,
Pemmaraju N
,
Jabbour E
, Sasaki K, Kanagal-Shamanna R, Patel K,
Jorgensen J
,
Garg N
, Wang X, Sondermann K, Cruz N, Wei C, Ayala A, Plunkett W,
Kantarjian H
,
Gandhi V
,
Wierda W
. Ibrutinib and Venetoclax for First-Line Treatment of CLL. N Engl J Med. 2019 05 30; 380(22):2095-2103.
PMID:
31141631
.
Citations:
139
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Strati P,
Takahashi K
, Peterson CB, Keating MJ, Thompson PA,
Daver NG
,
Jain N
,
Burger JA
,
Estrov Z
, O'Brien SM,
Kantarjian HM
,
Wierda WG
, Futreal PA,
Ferrajoli A
. Efficacy and predictors of response of lenalidomide and rituximab in patients with treatment-naive and relapsed CLL. Blood Adv. 2019 05 14; 3(9):1533-1539.
PMID:
31076409
; PMCID:
PMC6517659
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Hu B,
Patel KP
, Chen HC, Wang X, Wang F,
Luthra R
,
Routbort MJ
, Kanagal-Shamanna R, Medeiros LJ, Yin CC,
Zuo Z
,
Ok CY
,
Loghavi S
, Tang G, Tambaro FP, Thompson P, Burger J,
Jain N
,
Ferrajoli A
,
Bose P
,
Estrov Z
, Keating MJ,
Wierda WG
. Routine sequencing in CLL has prognostic implications and provides new insight into pathogenesis and targeted treatments. Br J Haematol. 2019 06; 185(5):852-864.
PMID:
30924136
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Jain P,
Kantarjian H
, Boddu PC,
Verstovsek S
,
Garcia-Manero G
,
Borthakur G
, Sasaki K,
Kadia TM
, Sam P, Ahaneku H, O'Brien S,
Estrov Z
, Ravandi F,
Jabbour E
,
Cortes JE
, Nogueras-Gonz?lez GM. Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs. Blood Adv. 2019 03 26; 3(6):851-861.
PMID:
30885996
; PMCID:
PMC6436011
.
Citations:
29
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Veletic I, Manshouri T,
Multani AS
, Yin CC, Chen L,
Verstovsek S
,
Estrov Z
. Myelofibrosis osteoclasts are clonal and functionally impaired. Blood. 2019 05 23; 133(21):2320-2324.
PMID:
30745304
; PMCID:
PMC6533604
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Cells
Yilmaz M, Wang F,
Loghavi S
,
Bueso-Ramos C
, Gumbs C, Little L, Song X, Zhang J,
Kadia T
,
Borthakur G
,
Jabbour E
,
Pemmaraju N
, Short N,
Garcia-Manero G
,
Estrov Z
,
Kantarjian H
,
Futreal A
,
Takahashi K
, Ravandi F. Late relapse in acute myeloid leukemia (AML): clonal evolution or therapy-related leukemia? Blood Cancer J. 2019 01 16; 9(2):7.
PMID:
30651532
; PMCID:
PMC6335405
.
Citations:
25
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Short NJ,
Kantarjian HM
,
Loghavi S
, Huang X, Qiao W,
Borthakur G
,
Kadia TM
,
Daver N
,
Ohanian M
,
Dinardo CD
,
Estrov Z
, Kanagal-Shamanna R, Maiti A,
Benton CB
,
Bose P
,
Alvarado Y
,
Jabbour E
,
Kornblau SM
,
Pemmaraju N
,
Jain N
, Gasior Y, Richie MA, Pierce S, Cortes J,
Konopleva M
,
Garcia-Manero G
, Ravandi F. Treatment with a 5-day versus a 10-day schedule of decitabine in older patients with newly diagnosed acute myeloid leukaemia: a randomised phase 2 trial. Lancet Haematol. 2019 Jan; 6(1):e29-e37.
PMID:
30545576
; PMCID:
PMC6563344
.
Citations:
32
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Burger JA
, Sivina M,
Jain N
, Kim E,
Kadia T
,
Estrov Z
, Nogueras-Gonzalez GM, Huang X,
Jorgensen J
, Li J, Cheng M, Clow F,
Ohanian M
,
Andreeff M
, Mathew T, Thompson P,
Kantarjian H
, O'Brien S,
Wierda WG
,
Ferrajoli A
, Keating MJ. Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia. Blood. 2019 03 07; 133(10):1011-1019.
PMID:
30530801
; PMCID:
PMC6405333
.
Citations:
65
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kanagal-Shamanna R, Jain P,
Patel KP
,
Routbort M
,
Bueso-Ramos C
, Alhalouli T,
Khoury JD
,
Luthra R
,
Ferrajoli A
, Keating M,
Jain N
,
Burger J
,
Estrov Z
,
Wierda W
,
Kantarjian HM
,
Medeiros LJ
. Targeted multigene deep sequencing of Bruton tyrosine kinase inhibitor-resistant chronic lymphocytic leukemia with disease progression and Richter transformation. Cancer. 2019 02 15; 125(4):559-574.
PMID:
30508305
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Short NJ,
Jabbour E
,
Naqvi K
, Patel A,
Ning J
, Sasaki K, Nogueras-Gonzalez GM,
Bose P
,
Kornblau SM
,
Takahashi K
,
Andreeff M
, Sanchez-Petitto G,
Estrov Z
,
Dinardo CD
, Montalban-Bravo G,
Konopleva M
,
Alvarado Y
,
Bhalla KN
,
Fiskus W
, Khouri M, Islam R,
Kantarjian H
,
Garcia-Manero G
. A phase II study of omacetaxine mepesuccinate for patients with higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia after failure of hypomethylating agents. Am J Hematol. 2019 01; 94(1):74-79.
PMID:
30328139
; PMCID:
PMC6570401
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Zulbaran-Rojas A, Lin HK,
Shi Q
,
Williams LA
, George B,
Garcia-Manero G
,
Jabbour E
, O'Brien S, Ravandi F,
Wierda W
,
Estrov Z
,
Borthakur G
,
Kadia T
,
Cleeland C
,
Cortes JE
,
Kantarjian H
. A prospective analysis of symptom burden for patients with chronic myeloid leukemia in chronic phase treated with frontline second- and third-generation tyrosine kinase inhibitors. Cancer Med. 2018 11; 7(11):5457-5469.
PMID:
30318751
; PMCID:
PMC6246941
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Assi R,
Garcia-Manero G
, Ravandi F,
Borthakur G
,
Daver NG
,
Jabbour E
,
Burger J
,
Estrov Z
,
Dinardo CD
,
Alvarado Y
, Hendrickson S,
Ferrajoli A
,
Wierda W
, Cortes J,
Kantarjian H
,
Kadia TM
. Addition of eltrombopag to immunosuppressive therapy in patients with newly diagnosed aplastic anemia. Cancer. 2018 11 01; 124(21):4192-4201.
PMID:
30307606
; PMCID:
PMC6800043
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jain P, Kanagal-Shamanna R,
Konoplev S
,
Zuo Z
,
Estrov Z
. Biclonal IGHV-4-34 hairy cell leukemia variant and CLL - successful treatment with ibrutinib and venetoclax. Am J Hematol. 2018 12; 93(12):1568-1569.
PMID:
30152528
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Boddu P,
Borthakur G
, Koneru M, Huang X,
Naqvi K
,
Wierda W
,
Bose P
,
Jabbour E
,
Estrov Z
,
Burger J
,
Alvarado Y
, Deshmukh A, Patel A, Cavazos A, Han L,
Cortes JE
,
Kantarjian H
,
Andreeff M
,
Konopleva M
. Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia. Front Oncol. 2018; 8:369.
PMID:
30319961
; PMCID:
PMC6167965
.
Citations:
10
Rozovski U, Harris DM, Li P, Liu Z, Jain P,
Ferrajoli A
,
Burger J
, Thompson P,
Jain N
,
Wierda W
, Keating MJ,
Estrov Z
. STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells. Oncotarget. 2018 Sep 14; 9(72):33710-33718.
PMID:
30263097
; PMCID:
PMC6154750
.
Citations:
4
Fields:
Neo
Neoplasms
Abaza Y, Hidalgo-Lopez JE,
Verstovsek S
,
Jabbour E
, Ravandi F,
Borthakur G
,
Estrov Z
,
Alvarado Y
, Burger J, Schneider H, Soltysiak KA, Wei Y,
Kantarjian HM
,
Bueso-Ramos CE
,
Garcia-Manero G
. Phase I study of ruxolitinib in previously treated patients with low or intermediate-1 risk myelodysplastic syndrome with evidence of NF-kB activation. Leuk Res. 2018 10; 73:78-85.
PMID:
30245189
; PMCID:
PMC6750211
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Masarova L,
Verstovsek S
, Hidalgo-Lopez JE,
Pemmaraju N
,
Bose P
,
Estrov Z
,
Jabbour EJ
,
Ravandi-Kashani F
,
Takahashi K
,
Cortes JE
, Ning J,
Ohanian M
,
Alvarado Y
, Zhou L, Pierce S, Gergis R,
Patel KP
,
Luthra R
,
Kadia TM
,
DiNardo CD
,
Borthakur G
,
Bhalla K
,
Garcia-Manero G
,
Bueso-Ramos CE
,
Kantarjian HM
,
Daver N
. A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis. Blood. 2018 10 18; 132(16):1664-1674.
PMID:
30185431
; PMCID:
PMC6265645
.
Citations:
28
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Ohanian M
,
Garcia-Manero G
, Levis M,
Jabbour E
,
Daver N
,
Borthakur G
,
Kadia T
, Pierce S,
Burger J
, Richie MA, Patel K,
Andreeff M
,
Estrov Z
, Cortes J,
Kantarjian H
, Ravandi F. Sorafenib Combined with 5-azacytidine in Older Patients with Untreated FLT3-ITD Mutated Acute Myeloid Leukemia. Am J Hematol. 2018 09; 93(9):1136-1141.
PMID:
30028037
.
Citations:
30
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Rozovski U, Keating MJ,
Estrov Z
. Why Is the Immunoglobulin Heavy Chain Gene Mutation Status a Prognostic Indicator in Chronic Lymphocytic Leukemia? Acta Haematol. 2018; 140(1):51-54.
PMID:
30114695
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
Kadia TM
, Cortes J, Ravandi F,
Jabbour E
,
Konopleva M
,
Benton CB
,
Burger J
, Sasaki K,
Borthakur G
,
DiNardo CD
,
Pemmaraju N
,
Daver N
,
Ferrajoli A
, Wang X, Patel K,
Jorgensen JL
, Wang S, O'Brien S, Pierce S, Tuttle C,
Estrov Z
,
Verstovsek S
,
Garcia-Manero G
,
Kantarjian H
. Cladribine and low-dose cytarabine alternating with decitabine as front-line therapy for elderly patients with acute myeloid leukaemia: a phase 2 single-arm trial. Lancet Haematol. 2018 Sep; 5(9):e411-e421.
PMID:
30115541
; PMCID:
PMC6775639
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Veletic I, Manshouri T, Newberry KJ, Garnett J,
Verstovsek S
,
Estrov Z
. Pentraxin-3 plasma levels correlate with tumour burden and overall survival in patients with primary myelofibrosis. Br J Haematol. 2019 04; 185(2):382-386.
PMID:
30074241
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Abou Dalle I,
Cortes JE
, Pinnamaneni P,
Lamothe B
, Diaz Duque A, Randhawa J,
Pemmaraju N
,
Jabbour E
,
Ferrajoli A
,
Wierda WG
,
Estrov Z
,
Konopleva M
, Ravandi F,
Alvarado Y
,
Borthakur G
,
Gandhi V
,
Kantarjian HM
. A Pilot Phase II Study of Erlotinib for the Treatment of Patients with Relapsed/Refractory Acute Myeloid Leukemia. Acta Haematol. 2018; 140(1):30-39.
PMID:
30071517
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Ohanian M
, Rozovski U, Kanagal-Shamanna R, Abruzzo LV,
Loghavi S
,
Kadia T
,
Futreal A
,
Bhalla K
,
Zuo Z
,
Huh YO
,
Post SM
,
Ruvolo P
,
Garcia-Manero G
,
Andreeff M
,
Kornblau S
,
Borthakur G
,
Hu P
,
Medeiros LJ
,
Takahashi K
, Hornbaker MJ, Zhang J, Huang X,
Verstovsek S
,
Estrov Z
, Pierce S, Ravandi F,
Kantarjian HM
,
Bueso-Ramos CE
,
Cortes JE
, Nogueras-Gonz?lez GM. MYC protein expression is an important prognostic factor in acute myeloid leukemia. Leuk Lymphoma. 2019 01; 60(1):37-48.
PMID:
29741984
; PMCID:
PMC6226369
.
Citations:
27
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Naqvi K
,
Jabbour E
, Skinner J, Yilmaz M,
Ferrajoli A
,
Bose P
, Thompson P,
Alvarado Y
,
Jain N
,
Takahashi K
,
Burger J
,
Estrov Z
,
Borthakur G
,
Pemmaraju N
, Paul S, Cortes J,
Kantarjian HM
. Early results of lower dose dasatinib (50?mg daily) as frontline therapy for newly diagnosed chronic-phase chronic myeloid leukemia. Cancer. 2018 07 01; 124(13):2740-2747.
PMID:
29723397
; PMCID:
PMC6388399
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Rozovski U, Harris DM, Li P, Liu Z, Jain P,
Ferrajoli A
,
Burger J
, Thompson P,
Jain N
,
Wierda W
, Keating MJ,
Estrov Z
. STAT3-activated CD36 facilitates fatty acid uptake in chronic lymphocytic leukemia cells. Oncotarget. 2018 Apr 20; 9(30):21268-21280.
PMID:
29765537
; PMCID:
PMC5940394
.
Citations:
20
Fields:
Neo
Neoplasms
Thompson PA, Peterson CB, Strati P,
Jorgensen J
, Keating MJ, O'Brien SM,
Ferrajoli A
,
Burger JA
,
Estrov Z
,
Jain N
,
Kadia TM
,
Borthakur G
,
DiNardo CD
,
Daver N
,
Jabbour E
,
Wierda WG
. Serial minimal residual disease (MRD) monitoring during first-line FCR treatment for CLL may direct individualized therapeutic strategies. Leukemia. 2018 11; 32(11):2388-2398.
PMID:
29769624
; PMCID:
PMC6192870
.
Citations:
12
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Assi R,
Kantarjian HM
,
Kadia TM
,
Pemmaraju N
,
Jabbour E
,
Jain N
,
Daver N
,
Estrov Z
, Uehara T, Owa T,
Cortes JE
,
Borthakur G
. Final results of a phase 2, open-label study of indisulam, idarubicin, and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome. Cancer. 2018 07 01; 124(13):2758-2765.
PMID:
29660836
; PMCID:
PMC6800041
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Khan M,
Muzzafar T
,
Kantarjian H
, Badar I, Short N, Wang X, Chamoun K, Jain P,
DiNardo C
,
Pemmaraju N
,
Bose P
,
Borthakur G
, Cortes J,
Verstovsek S
,
Garcia-Manero G
,
Estrov Z
. Association of bone marrow fibrosis with inferior survival outcomes in chronic myelomonocytic leukemia. Ann Hematol. 2018 Jul; 97(7):1183-1191.
PMID:
29557496
; PMCID:
PMC6506234
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Cells
Rozovski U, Harris DM, Li P, Liu Z, Jain P,
Ferrajoli A
,
Burger J
, Thompson P,
Jain N
,
Wierda W
, Keating MJ,
Estrov Z
. Ibrutinib inhibits free fatty acid metabolism in chronic lymphocytic leukemia. Leuk Lymphoma. 2018 11; 59(11):2686-2691.
PMID:
29465264
; PMCID:
PMC6135679
.
Citations:
10
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Strati P,
Ferrajoli A
,
Wierda WG
,
Jain N
, Thompson PA, O'Brien SM,
Rezvani K
,
Kantarjian HM
,
Burger JA
, Hinojosa CO, Keating MJ,
Estrov Z
. Sustained long-lasting responses after lenalidomide discontinuation in patients with chronic lymphocytic leukemia. Leukemia. 2018 10; 32(10):2278-2281.
PMID:
29479067
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Jabbour E
, Ravandi F,
Kebriaei P
, Huang X, Short NJ, Thomas D, Sasaki K,
Rytting M
,
Jain N
,
Konopleva M
,
Garcia-Manero G
,
Champlin R
,
Marin D
,
Kadia T
, Cortes J,
Estrov Z
,
Takahashi K
, Patel Y, Khouri MR, Jacob J, Garris R, O'Brien S,
Kantarjian H
. Salvage Chemoimmunotherapy With Inotuzumab Ozogamicin Combined With Mini-Hyper-CVD for Patients With Relapsed or Refractory Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: A Phase 2 Clinical Trial. JAMA Oncol. 2018 Feb 01; 4(2):230-234.
PMID:
28859185
; PMCID:
PMC5838597
.
Citations:
43
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Takahashi K
, Hu B, Wang F, Yan Y, Kim E, Vitale C,
Patel KP
, Strati P, Gumbs C, Little L, Tippen S, Song X, Zhang J,
Jain N
, Thompson P,
Garcia-Manero G
,
Kantarjian H
,
Estrov Z
,
Do KA
, Keating M,
Burger JA
,
Wierda WG
, Futreal PA,
Ferrajoli A
. Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide. Blood. 2018 04 19; 131(16):1820-1832.
PMID:
29358183
; PMCID:
PMC5909764
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Sivina M, Kim E, Thenhausen T, Krohn-Grimberghe A,
Jain N
,
Estrov Z
,
Ferrajoli A
,
Wierda W
, Keating M,
Burger JA
, Schliffke S, von Wenserski L, Thiele B, Aky?z N, Falker-Gieske C, Statovci D, Oberle A, Bokemeyer C, Binder M. Dynamic changes of the normal B lymphocyte repertoire in CLL in response to ibrutinib or FCR chemo-immunotherapy. Oncoimmunology. 2018; 7(4):e1417720.
PMID:
29632735
; PMCID:
PMC5889203
.
Citations:
4
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Shaim H,
Estrov Z
, Harris D, Hernandez Sanabria M, Liu Z,
Ruvolo P
, Thompson PA,
Ferrajoli A
, Daher M,
Burger J
, Muftuoglu M, Imahashi N, Li L, Liu E, Alsuliman AS, Basar R, Nassif Kerbauy L, Sobieski C, Gokdemir E, Kondo K,
Wierda W
, Keating M,
Shpall EJ
, Rezvani K. The CXCR4-STAT3-IL-10 Pathway Controls the Immunoregulatory Function of Chronic Lymphocytic Leukemia and Is Modulated by Lenalidomide. Front Immunol. 2017; 8:1773.
PMID:
29379494
; PMCID:
PMC5775272
.
Citations:
13
Fields:
All
Allergy and Immunology
Montalban-Bravo G,
Takahashi K
, Patel K, Wang F, Xingzhi S, Nogueras GM, Huang X, Pierola AA,
Jabbour E
,
Colla S
, Borthakur G,
Daver N
,
Estrov Z
,
Kadia T
,
Pemmaraju N
, Ravandi F,
Bueso-Ramos C
, Chamseddine A,
Konopleva M
, Zhang J,
Kantarjian H
,
Futreal A
,
Garcia-Manero G
, Ga?an-Gomez I. Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms. Oncotarget. 2018 Feb 09; 9(11):9714-9727.
PMID:
29515765
; PMCID:
PMC5839396
.
Citations:
23
Fields:
Neo
Neoplasms
Assi R,
Kantarjian HM
,
Garcia-Manero G
,
Cortes JE
,
Pemmaraju N
, Wang X, Nogueras-Gonzalez G,
Jabbour E
,
Bose P
,
Kadia T
,
Dinardo CD
, Patel K,
Bueso-Ramos C
, Zhou L, Pierce S, Gergis R, Tuttle C,
Borthakur G
,
Estrov Z
,
Luthra R
, Hidalgo-Lopez J,
Verstovsek S
,
Daver N
. A phase II trial of ruxolitinib in combination with azacytidine in myelodysplastic syndrome/myeloproliferative neoplasms. Am J Hematol. 2018 02; 93(2):277-285.
PMID:
29134664
.
Citations:
18
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Jain P, Kanagal-Shamanna R, Rozovski U, Sarwari N, Tam C,
Wierda WG
, Thompson PA,
Jain N
,
Luthra R
, Quesada A, Sanchez-Petitto G,
Ferrajoli A
,
Burger J
,
Kantarjian H
, Cortes J, O'Brien S, Keating MJ,
Estrov Z
, Nogueras Gonz?lez GM. The absolute percent deviation of IGHV mutation rather than a 98% cut-off predicts survival of chronic lymphocytic leukaemia patients treated with fludarabine, cyclophosphamide and rituximab. Br J Haematol. 2018 01; 180(1):33-40.
PMID:
29164608
; PMCID:
PMC5745295
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Cells
Boddu P, Masarova L,
Verstovsek S
, Strati P,
Kantarjian H
, Cortes J,
Estrov Z
, Pierce S,
Pemmaraju N
. Patient characteristics and outcomes in adolescents and young adults with classical Philadelphia chromosome-negative myeloproliferative neoplasms. Ann Hematol. 2018 Jan; 97(1):109-121.
PMID:
29143068
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Kondo K, Shaim H, Thompson PA, Burger JA, Keating M,
Estrov Z
, Harris D, Kim E,
Ferrajoli A
, Daher M, Basar R, Muftuoglu M, Imahashi N, Alsuliman A, Sobieski C, Gokdemir E,
Wierda W
, Jain N, Liu E,
Shpall EJ
,
Rezvani K
. Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway. Leukemia. 2018 04; 32(4):960-970.
PMID:
28972595
; PMCID:
PMC6128536
.
Citations:
55
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Abaza YM,
Kadia TM
,
Jabbour EJ
,
Konopleva MY
,
Borthakur G
,
Ferrajoli A
,
Estrov Z
,
Wierda WG
, Alfonso A, Chong TH, Chuah C, Koh LP, Goh BC, Chang JE, Durkes DE, Foudray MC,
Kantarjian HM
, Dong XQ,
Garcia-Manero G
. Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies. Cancer. 2017 Dec 15; 123(24):4851-4859.
PMID:
28841236
; PMCID:
PMC5901648
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Strati P, Keating MJ,
Burger JA
, O'Brien SM,
Wierda WG
,
Estrov Z
, Zacharian G,
Ferrajoli A
. Consolidation treatment with lenalidomide following front-line or salvage chemoimmunotherapy in chronic lymphocytic leukemia. Haematologica. 2017 12; 102(12):e494-e496.
PMID:
28798068
; PMCID:
PMC5709120
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Rozovski U, Harris DM, Li P, Liu Z, Jain P, Veletic I,
Ferrajoli A
,
Burger J
, Thompson P,
Jain N
,
Wierda W
, Keating MJ,
Estrov Z
. Activation of the B-cell receptor successively activates NF-?B and STAT3 in chronic lymphocytic leukemia cells. Int J Cancer. 2017 11 15; 141(10):2076-2081.
PMID:
28722170
; PMCID:
PMC5749978
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jabbour E
, Short NJ, Montalban-Bravo G, Huang X,
Bueso-Ramos C
, Qiao W, Yang H, Zhao C,
Kadia T
,
Borthakur G
,
Pemmaraju N
, Sasaki K,
Estrov Z
, Cortes J, Ravandi F,
Alvarado Y
, Komrokji R, Sekeres MA, Steensma DP, DeZern A, Roboz G,
Kantarjian H
,
Garcia-Manero G
. Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN. Blood. 2017 09 28; 130(13):1514-1522.
PMID:
28774880
; PMCID:
PMC5620419
.
Citations:
45
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Jain P,
Kantarjian H
,
Jain N
, Short NJ, Yin CC, Kanagal-Shamanna R,
Khoury J
,
Konopleva M
, Sasaki K,
Kadia TM
, Garris R, Pierce S,
Estrov Z
,
Wierda W
, Cortes J, O'Brien S, Ravandi F,
Jabbour E
. Clinical characteristics and outcomes of previously untreated patients with adult onset T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma with hyper-CVAD based regimens. Am J Hematol. 2017 10; 92(10):E595-E597.
PMID:
28646517
; PMCID:
PMC5689471
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
ten Hacken E, Back JW, Shimanovskaya E, Kim E,
Burks J
,
Wierda WG
,
Estrov Z
, Keating MJ,
Ferrajoli A
, Stamatopoulos K,
Burger JA
, Gounari M, Scarf? L, Ponzoni M, Ramirez GA, Ghia P. Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia. Haematologica. 2017 10; 102(10):e394-e396.
PMID:
28751563
; PMCID:
PMC5622869
.
Citations:
5
Fields:
Hem
Hematology
Translation:
Humans
Cells
Jain P,
Kantarjian HM
, Ghorab A, Sasaki K,
Jabbour EJ
, Nogueras Gonzalez G, Kanagal-Shamanna R, Issa GC,
Garcia-Manero G
, Kc D, Dellasala S, Pierce S,
Konopleva M
,
Wierda WG
,
Verstovsek S
,
Daver NG
,
Kadia TM
,
Borthakur G
, O'Brien S,
Estrov Z
, Ravandi F,
Cortes JE
. Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients. Cancer. 2017 Nov 15; 123(22):4391-4402.
PMID:
28743165
; PMCID:
PMC5673547
.
Citations:
47
Fields:
Neo
Neoplasms
Translation:
Humans
Jabbour E
, Guastad Daver N, Short NJ, Huang X, Chen HC, Maiti A, Ravandi F, Cortes J, Abi Aad S,
Garcia-Manero G
,
Estrov Z
,
Kadia T
, O'Brien S,
Dabaja B
,
Bueso-Ramos C
, Strati P, Bivins C, Pierce S,
Kantarjian H
. Factors associated with risk of central nervous system relapse in patients with non-core binding factor acute myeloid leukemia. Am J Hematol. 2017 Sep; 92(9):924-928.
PMID:
28556489
; PMCID:
PMC5901967
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Boddu P,
Kantarjian HM
,
Garcia-Manero G
, Ravandi F,
Verstovsek S
,
Jabbour E
,
Borthakur G
,
Konopleva M
,
Bhalla KN
,
Daver N
,
DiNardo CD
,
Benton CB
,
Takahashi K
,
Estrov Z
, Pierce SR,
Andreeff M
,
Cortes JE
,
Kadia TM
. Treated secondary acute myeloid leukemia: a distinct high-risk subset of AML with adverse prognosis. Blood Adv. 2017 Jul 25; 1(17):1312-1323.
PMID:
29296774
; PMCID:
PMC5727976
.
Citations:
26
Fields:
Hem
Hematology
Short NJ,
Kantarjian H
, Ravandi F, Huang X, Xiao L,
Garcia-Manero G
, Plunkett W,
Gandhi V
, Sasaki K,
Pemmaraju N
,
Daver NG
,
Borthakur G
,
Jain N
,
Konopleva M
,
Estrov Z
,
Kadia TM
,
Wierda WG
,
DiNardo CD
, Brandt M, O'Brien SM,
Cortes JE
,
Jabbour E
. A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia. Leuk Lymphoma. 2018 04; 59(4):813-820.
PMID:
28718728
; PMCID:
PMC5773400
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jabbour E
, Short NJ, Ravandi F, Huang X, Xiao L,
Garcia-Manero G
, Plunkett W,
Gandhi V
, Sasaki K,
Pemmaraju N
,
Daver NG
,
Borthakur G
,
Jain N
,
Konopleva M
,
Estrov Z
,
Kadia TM
,
Wierda WG
,
DiNardo CD
, Brandt M, O'Brien SM,
Cortes JE
,
Kantarjian H
. A randomized phase 2 study of idarubicin and cytarabine with clofarabine or fludarabine in patients with newly diagnosed acute myeloid leukemia. Cancer. 2017 Nov 15; 123(22):4430-4439.
PMID:
28708931
; PMCID:
PMC5739034
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jain P, Aoki E, Keating M,
Wierda WG
, O'Brien S, Gonzalez GN,
Ferrajoli A
, Jain N, Thompson PA, Jabbour E, Kanagal-Shamanna R, Pierce S, Alousi A,
Hosing C
,
Khouri I
,
Estrov Z
, Cortes J,
Kantarjian H
, Ravandi F, Kadia TM. Characteristics, outcomes, prognostic factors and treatment of patients with T-cell prolymphocytic leukemia (T-PLL). Ann Oncol. 2017 Jul 01; 28(7):1554-1559.
PMID:
28379307
; PMCID:
PMC5834082
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Kanagal-Shamanna R, Jain P,
Takahashi K
, Short NJ, Tang G, Issa GC, Ravandi F,
Garcia-Manero G
, Yin CC,
Luthra R
,
Patel KP
,
Khoury JD
, Montalban-Bravo G, Sasaki K,
Kadia TM
,
Borthakur G
,
Konopleva M
,
Jain N
, Garris R, Pierce S,
Wierda W
,
Estrov Z
, Cortes J, O'Brien S,
Kantarjian HM
,
Jabbour E
. TP53 mutation does not confer a poor outcome in adult patients with acute lymphoblastic leukemia who are treated with frontline hyper-CVAD-based regimens. Cancer. 2017 Oct 01; 123(19):3717-3724.
PMID:
28608976
; PMCID:
PMC5689475
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Daher M, Hidalgo Lopez JE, Randhawa JK, Jabbar KJ, Wei Y,
Pemmaraju N
,
Borthakur G
,
Kadia T
,
Konopleva M
,
Kantarjian HM
, Hearn K,
Estrov Z
, Reyes S,
Bueso-Ramos CE
,
Garcia-Manero G
. An exploratory clinical trial of bortezomib in patients with lower risk myelodysplastic syndromes. Am J Hematol. 2017 Jul; 92(7):674-682.
PMID:
28370157
; PMCID:
PMC5580683
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Kanagal-Shamanna R, Medeiros LJ,
Estrov Z
, Yin CC,
Verstovsek S
,
Konoplev S
,
Jorgensen JL
, Mohammad MM,
Miranda RN
, Zhao C, Lee J,
Zuo Z
,
Bueso-Ramos CE
, Hidalgo-L?pez JE. Morphologic and Molecular Characteristics of De Novo AML With JAK2 V617F Mutation. J Natl Compr Canc Netw. 2017 06; 15(6):790-796.
PMID:
28596259
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Alfonso A, Montalban-Bravo G,
Takahashi K
,
Jabbour EJ
,
Kadia T
, Ravandi F, Cortes J,
Estrov Z
,
Borthakur G
,
Pemmaraju N
,
Konopleva M
,
Bueso-Ramos C
, Pierce S,
Kantarjian H
,
Garcia-Manero G
. Natural history of chronic myelomonocytic leukemia treated with hypomethylating agents. Am J Hematol. 2017 Jul; 92(7):599-606.
PMID:
28370097
; PMCID:
PMC5553721
.
Citations:
17
Fields:
Hem
Hematology
Translation:
Humans
Cells
Masarova L, Todisco G, Manshouri T, Newberry KJ,
Cortes JE
,
Kantarjian HM
,
Estrov Z
,
Verstovsek S
. Therapy-related myelofibrosis does not appear to exist. Blood Adv. 2017 Jun 13; 1(14):863-866.
PMID:
29296729
; PMCID:
PMC5737601
.
Citations:
1
Fields:
Hem
Hematology
Short NJ,
Kantarjian HM
, Ko H,
Khoury JD
, Ravandi F, Thomas DA,
Garcia-Manero G
, Khouri M,
Cortes JE
,
Wierda WG
,
Verstovsek S
,
Estrov Z
,
Ferrajoli A
, Thompson PA, Pierce S, O'Brien SM,
Jabbour E
. Outcomes of adults with relapsed or refractory Burkitt and high-grade B-cell leukemia/lymphoma. Am J Hematol. 2017 06; 92(6):E114-E117.
PMID:
28295472
; PMCID:
PMC5828013
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Jain P, Wang SA, Yin CC, Abaza Y,
Verstovsek S
,
Estrov Z
. A case of lymphocytic variant hypereosinophilic syndrome with sub-diagnostic systemic mastocytosis. Blood Res. 2017 Mar; 52(1):71-73.
PMID:
28401108
; PMCID:
PMC5383595
.
Citations:
Montalban-Bravo G, Huang X, Naqvi K, Jabbour E, Borthakur G, DiNardo CD, Pemmaraju N, Cortes J,
Verstovsek S
, Kadia T, Daver N,
Wierda W
, Alvarado Y,
Konopleva M
, Ravandi F,
Estrov Z
, Jain N, Alfonso A, Brandt M, Sneed T, Chen HC, Yang H,
Bueso-Ramos C
, Pierce S, Estey E, Bohannan Z,
Kantarjian HM
,
Garcia-Manero G
. A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials. Leukemia. 2017 07; 31(7):1659.
PMID:
28338082
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Thompson PA, Stingo F, Keating MJ,
Wierda WG
, O'Brien SM,
Estrov Z
, Ledesma C, Rezvani K,
Qazilbash M
, Shah N,
Parmar S
,
Popat U
,
Anderlini P
, Yago N,
Ciurea SO
,
Kebriaei P
,
Champlin R
,
Shpall EJ
,
Hosing CM
. Long-term follow-up of patients receiving allogeneic stem cell transplant for chronic lymphocytic leukaemia: mixed T-cell chimerism is associated with high relapse risk and inferior survival. Br J Haematol. 2017 05; 177(4):567-577.
PMID:
28295181
; PMCID:
PMC7394482
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Masarova L,
Patel KP
, Newberry KJ, Cortes J,
Borthakur G
,
Konopleva M
,
Estrov Z
,
Kantarjian H
,
Verstovsek S
. Pegylated interferon alfa-2a in patients with essential thrombocythaemia or polycythaemia vera: a post-hoc, median 83 month follow-up of an open-label, phase 2 trial. Lancet Haematol. 2017 Apr; 4(4):e165-e175.
PMID:
28291640
; PMCID:
PMC5421384
.
Citations:
42
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jabbour E
, Strati P, Cabrero M, O'Brien S, Ravandi F,
Bueso-Ramos C
, Wei Q, Hu J, Abi Aad S, Short NJ,
Dinardo C
,
Daver N
,
Kadia T
,
Wierda W
, Wei Y,
Colla S
,
Borthakur G
, Cortes J,
Estrov Z
,
Kantarjian H
,
Garcia-Manero G
. Impact of achievement of complete cytogenetic response on outcome in patients with myelodysplastic syndromes treated with hypomethylating agents. Am J Hematol. 2017 Apr; 92(4):351-358.
PMID:
28076892
; PMCID:
PMC5439522
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Cells
Maiti A, Cortes J,
Ferrajoli A
,
Estrov Z
,
Borthakur G
,
Garcia-Manero G
,
Jabbour E
, Ravandi F, O'Brien S,
Kantarjian H
. Phase II trial of homoharringtonine with imatinib in chronic, accelerated, and blast phase chronic myeloid leukemia. Leuk Lymphoma. 2017 09; 58(9):1-6.
PMID:
28278723
; PMCID:
PMC5478443
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Pemmaraju N
, Jain P,
Medeiros LJ
, Jorgenson JL,
Jain N
, Willis J,
Kontoyiannis DP
,
Estrov Z
,
Wierda WG
. PET-positive lymphadenopathy in CLL-Not always Richter transformation. Am J Hematol. 2017 04; 92(4):405-406.
PMID:
27677095
; PMCID:
PMC5352509
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Jain P, Thompson PA, Keating M,
Estrov Z
,
Ferrajoli A
,
Jain N
,
Kantarjian H
,
Burger JA
, O'Brien S,
Wierda WG
. Long-term outcomes for patients with chronic lymphocytic leukemia who discontinue ibrutinib. Cancer. 2017 Jun 15; 123(12):2268-2273.
PMID:
28171709
; PMCID:
PMC5980235
.
Citations:
42
Fields:
Neo
Neoplasms
Translation:
Humans
Rozovski U, Harris DM, Li P, Liu Z, Jain P, Veletic I,
Ferrajoli A
,
Burger J
, O'Brien S,
Bose P
, Thompson P,
Jain N
,
Wierda W
, Keating MJ,
Estrov Z
. Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex. Mol Cancer Res. 2017 05; 15(5):610-618.
PMID:
28130399
; PMCID:
PMC5415425
.
Citations:
12
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Jain P, Keating M, Renner S,
Cleeland C
, Xuelin H, Gonzalez GN, Harris D, Li P, Liu Z, Veletic I, Rozovski U,
Jain N
, Thompson P,
Bose P
,
DiNardo C
,
Ferrajoli A
, O'Brien S,
Burger J
,
Wierda W
,
Verstovsek S
,
Kantarjian H
,
Estrov Z
. Ruxolitinib for symptom control in patients with chronic lymphocytic leukaemia: a single-group, phase 2 trial. Lancet Haematol. 2017 Feb; 4(2):e67-e74.
PMID:
28089238
; PMCID:
PMC5356368
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Yin Q, Sivina M, Robins H, Yusko E, Vignali M, O'Brien S, Keating MJ,
Ferrajoli A
,
Estrov Z
,
Jain N
,
Wierda WG
,
Burger JA
. Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia. J Immunol. 2017 02 15; 198(4):1740-1747.
PMID:
28077600
; PMCID:
PMC5296363
.
Citations:
53
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Abaza Y,
Kantarjian H
,
Garcia-Manero G
, Estey E,
Borthakur G
,
Jabbour E
, Faderl S, O'Brien S,
Wierda W
, Pierce S, Brandt M, McCue D,
Luthra R
, Patel K,
Kornblau S
,
Kadia T
,
Daver N
,
DiNardo C
,
Jain N
,
Verstovsek S
,
Ferrajoli A
,
Andreeff M
,
Konopleva M
,
Estrov Z
, Foudray M, McCue D, Cortes J, Ravandi F. Long-term outcome of acute promyelocytic leukemia treated with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab. Blood. 2017 03 09; 129(10):1275-1283.
PMID:
28003274
; PMCID:
PMC5413297
.
Citations:
73
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Shah AR,
Muzzafar T
, Assi R,
Schellingerhout D
,
Estrov Z
, Tamamyan G,
Kantarjian H
,
Daver N
. Hemophagocytic lymphohistiocytosis in adults: An under recognized entity. BBA Clin. 2017 Jun; 7:36-40.
PMID:
28070498
; PMCID:
PMC5219626
.
Citations:
7
Ohanian M
,
Pemmaraju N
, Rozovski U, Alattar ML,
Estrov Z
,
Kundra V
,
Tung C
, Ravandi F, Manning J, Abruzzo LV. Ocular extramedullary myeloid leukaemia. Br J Haematol. 2018 03; 180(5):738-740.
PMID:
27879987
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Montalban-Bravo G, Huang X, Naqvi K, Jabbour E, Borthakur G, DiNardo CD, Pemmaraju N, Cortes J,
Verstovsek S
, Kadia T, Daver N,
Wierda W
, Alvarado Y,
Konopleva M
, Ravandi F,
Estrov Z
, Jain N, Alfonso A,
Brandt M
, Sneed T, Chen HC, Yang H,
Bueso-Ramos C
, Pierce S, Estey E, Bohannan Z,
Kantarjian HM
,
Garcia-Manero G
. A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials. Leukemia. 2017 02; 31(2):318-324.
PMID:
27795561
.
Citations:
8
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Koller PB,
Kantarjian HM
, Nogueras-Gonzalez GM,
Jabbour E
,
Verstovsek S
,
Borthakur G
,
Estrov Z
,
Wierda WG
,
Garcia-Manero G
,
Ferrajoli A
, Ravandi F, O'Brien SM,
Cortes JE
. Chronic myeloid leukemia among patients with a history of prior malignancies: A tale of dual survivorship. Cancer. 2017 02 15; 123(4):609-616.
PMID:
27763690
; PMCID:
PMC5293656
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P, Keating MJ,
Wierda WG
, Sivina M, Thompson PA,
Ferrajoli A
,
Estrov Z
,
Kantarjian H
, O'Brien S,
Burger JA
. Long-term Follow-up of Treatment with Ibrutinib and Rituximab in Patients with High-Risk Chronic Lymphocytic Leukemia. Clin Cancer Res. 2017 May 01; 23(9):2154-2158.
PMID:
27797975
; PMCID:
PMC5397369
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Rozovski U,
Verstovsek S
, Manshouri T, Dembitz V, Bozinovic K, Newberry K, Zhang Y, Bove JE, Pierce S,
Kantarjian H
,
Estrov Z
. An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis. Haematologica. 2017 01; 102(1):79-84.
PMID:
27686378
; PMCID:
PMC5210235
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Ravandi F,
Jorgensen J
,
Borthakur G
,
Jabbour E
,
Kadia T
, Pierce S, Brandt M, Wang S,
Konoplev S
, Wang X, Huang X,
Daver N
,
DiNardo C
,
Andreeff M
,
Konopleva M
,
Estrov Z
,
Garcia-Manero G
, Cortes J,
Kantarjian H
. Persistence of minimal residual disease assessed by multiparameter flow cytometry is highly prognostic in younger patients with acute myeloid leukemia. Cancer. 2017 02 01; 123(3):426-435.
PMID:
27657543
; PMCID:
PMC5258784
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P, Kanagal-Shamanna R,
Wierda W
, Keating M, Sarwari N, Rozovski U, Thompson P,
Burger J
,
Kantarjian H
,
Patel KP
,
Medeiros LJ
,
Luthra R
,
Estrov Z
. Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia. Am J Hematol. 2016 11; 91(11):E478-E479.
PMID:
27468087
; PMCID:
PMC5073031
.
Citations:
9
Fields:
Hem
Hematology
Translation:
Humans
Ten Hacken E, Sivina M, Kim E, O'Brien S,
Wierda WG
,
Ferrajoli A
,
Estrov Z
, Keating MJ, Oellerich T,
Burger JA
, Scielzo C, Ghia P, Caligaris-Cappio F. Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia. J Immunol. 2016 09 15; 197(6):2522-31.
PMID:
27534555
; PMCID:
PMC5010921
.
Citations:
13
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Verstovsek S
, Manshouri T, Pilling D,
Bueso-Ramos CE
, Newberry KJ, Prijic S, Knez L, Bozinovic K, Harris DM, Spaeth EL,
Post SM
,
Multani AS
, Rampal RK, Ahn J, Levine RL,
Creighton CJ
,
Kantarjian HM
,
Estrov Z
. Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis. J Exp Med. 2016 08 22; 213(9):1723-40.
PMID:
27481130
; PMCID:
PMC4995084
.
Citations:
69
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Kadia TM
, Jain P, Ravandi F,
Garcia-Manero G
, Andreef M,
Takahashi K
,
Borthakur G
,
Jabbour E
,
Konopleva M
,
Daver NG
,
Dinardo C
, Pierce S, Kanagal-Shamanna R, Patel K,
Estrov Z
, Cortes J,
Kantarjian HM
. TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes. Cancer. 2016 Nov 15; 122(22):3484-3491.
PMID:
27463065
; PMCID:
PMC5269552
.
Citations:
71
Fields:
Neo
Neoplasms
Rozovski U, Hazan-Halevy I,
Calin G
, Harris D, Li P, Liu Z, Keating MJ,
Estrov Z
. Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome. J Vis Exp. 2016 06 15; (112).
PMID:
27341356
; PMCID:
PMC4927797
.
Citations:
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Cells
Rozovski U, Harris DM, Li P, Liu Z, Wu JY, Grgurevic S, Faderl S,
Ferrajoli A
,
Wierda WG
, Martinez M,
Verstovsek S
, Keating MJ,
Estrov Z
. At High Levels, Constitutively Activated STAT3 Induces Apoptosis of Chronic Lymphocytic Leukemia Cells. J Immunol. 2016 05 15; 196(10):4400-9.
PMID:
27076684
; PMCID:
PMC4868805
.
Citations:
15
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Liu PP, Liu J, Jiang WQ, Carew JS, Ogasawara MA, Pelicano H, Croce CM,
Estrov Z
, Xu RH, Keating MJ, Huang P. Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with an antiangina drug perhexiline. Oncogene. 2016 10 27; 35(43):5663-5673.
PMID:
27065330
; PMCID:
PMC5064824
.
Citations:
31
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Vitale C, Ahn IE, Sivina M,
Ferrajoli A
,
Wierda WG
,
Estrov Z
,
Konoplev SN
,
Jain N
, O'Brien S, Farooqui M, Keating MJ, Wiestner A,
Burger JA
. Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib. Haematologica. 2016 06; 101(6):e254-8.
PMID:
27013651
; PMCID:
PMC5013951
.
Citations:
16
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Takahashi K
, Patel K,
Bueso-Ramos C
, Zhang J, Gumbs C,
Jabbour E
,
Kadia T
, Andreff M,
Konopleva M
,
DiNardo C
,
Daver N
, Cortes J,
Estrov Z
,
Futreal A
,
Kantarjian H
,
Garcia-Manero G
. Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents. Oncotarget. 2016 Mar 22; 7(12):14172-87.
PMID:
26871476
; PMCID:
PMC4924706
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jain P, Tang G,
Huh YO
, Yin CC,
Zuo Z
,
Pemmaraju N
,
Estrov Z
,
Daver N
. Philadelphia-positive dimorphic blasts in mixed-phenotype acute leukemia with TET2 mutation. Am J Hematol. 2016 06; 91(6):647-8.
PMID:
26799924
; PMCID:
PMC4870100
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Cells
Jain P, Tang G,
Konoplev SN
, Kanagal-Shamanna R, Wang SA,
Pemmaraju N
,
Daver N
,
Estrov Z
. Synchronous del5q myelodysplastic syndrome (del5qMDS) and adult B-cell acute lymphoblastic leukemia (B-ALL) with TET2 and TP53 mutations. Am J Hematol. 2016 Mar; 91(3):354-5.
PMID:
26437693
; PMCID:
PMC4764477
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Jain P,
Kantarjian H
,
Patel KP
, Gonzalez GN,
Luthra R
,
Kanagal Shamanna R
, Sasaki K,
Jabbour E
, Romo CG,
Kadia TM
,
Pemmaraju N
,
Daver N
,
Borthakur G
,
Estrov Z
, Ravandi F, O'Brien S, Cortes J. Impact of BCR-ABL transcript type on outcome in patients with chronic-phase CML treated with tyrosine kinase inhibitors. Blood. 2016 Mar 10; 127(10):1269-75.
PMID:
26729897
; PMCID:
PMC4786836
.
Citations:
50
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Jain P,
Verstovsek S
, Wang W,
Loghavi S
,
Torres HA
,
Estrov Z
,
Patel KP
,
Pemmaraju N
. DNMT3A, TET2, and JAK2 mutations in polycythemia vera following long-term remission of secondary acute myeloid leukemia. Leuk Lymphoma. 2016 08; 57(8):1969-73.
PMID:
26700872
; PMCID:
PMC4919228
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Rozovski U, Hazan-Halevy I, Barzilai M, Keating MJ,
Estrov Z
. Metabolism pathways in chronic lymphocytic leukemia. Leuk Lymphoma. 2016; 57(4):758-65.
PMID:
26643954
; PMCID:
PMC4794359
.
Citations:
24
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Takahashi K
,
Kantarjian H
,
Garcia-Manero G
,
Borthakur G
,
Kadia T
,
DiNardo C
,
Jabbour E
, Pierce S,
Estrov Z
,
Konopleva M
,
Andreeff M
, Ravandi F, Cortes J. Clofarabine Plus Low-Dose Cytarabine Is as Effective as and Less Toxic Than Intensive Chemotherapy in Elderly AML Patients. Clin Lymphoma Myeloma Leuk. 2016 Mar; 16(3):163-8.e1-2.
PMID:
26752456
; PMCID:
PMC4804759
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Thompson PA, O'Brien SM, Xiao L, Wang X,
Burger JA
,
Jain N
,
Ferrajoli A
,
Estrov Z
, Keating MJ,
Wierda WG
. ?2 -microglobulin normalization within 6 months of ibrutinib-based treatment is associated with superior progression-free survival in patients with chronic lymphocytic leukemia. Cancer. 2016 Feb 15; 122(4):565-73.
PMID:
26588193
; PMCID:
PMC4813299
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ravandi F,
Jorgensen JL
, O'Brien SM,
Jabbour E
, Thomas DA,
Borthakur G
, Garris R, Huang X,
Garcia-Manero G
,
Burger JA
,
Ferrajoli A
,
Wierda W
,
Kadia T
,
Jain N
, Wang SA, Konoplev S,
Kebriaei P
,
Champlin RE
, McCue D,
Estrov Z
,
Cortes JE
,
Kantarjian HM
. Minimal residual disease assessed by multi-parameter flow cytometry is highly prognostic in adult patients with acute lymphoblastic leukaemia. Br J Haematol. 2016 Feb; 172(3):392-400.
PMID:
26492205
; PMCID:
PMC4826052
.
Citations:
38
Fields:
Hem
Hematology
Translation:
Humans
Todisco G, Manshouri T,
Verstovsek S
, Masarova L, Pierce SA, Keating MJ,
Estrov Z
. Chronic lymphocytic leukemia and myeloproliferative neoplasms concurrently diagnosed: clinical and biological characteristics. Leuk Lymphoma. 2016 May; 57(5):1054-9.
PMID:
26402369
; PMCID:
PMC4837105
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Jabbour E
,
Kantarjian H
, Ravandi F, Thomas D, Huang X, Faderl S,
Pemmaraju N
,
Daver N
,
Garcia-Manero G
, Sasaki K, Cortes J, Garris R, Yin CC,
Khoury JD
,
Jorgensen J
,
Estrov Z
, Bohannan Z,
Konopleva M
,
Kadia T
,
Jain N
,
DiNardo C
,
Wierda W
, Jeanis V, O'Brien S. Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a single-centre, phase 2 study. Lancet Oncol. 2015 Nov; 16(15):1547-1555.
PMID:
26432046
; PMCID:
PMC4816046
.
Citations:
83
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Masarova L, Cherry M, Newberry KJ,
Estrov Z
,
Cortes JE
,
Kantarjian HM
,
Verstovsek S
. Secondary solid tumors and lymphoma in patients with essential thrombocythemia and polycythemia vera - single center experience. Leuk Lymphoma. 2016; 57(1):237-9.
PMID:
25904378
; PMCID:
PMC4712116
.
Citations:
14
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ravandi F, O'Brien SM,
Cortes JE
, Thomas DM, Garris R, Faderl S,
Burger JA
,
Rytting ME
,
Ferrajoli A
,
Wierda WG
,
Verstovsek S
,
Champlin R
,
Kebriaei P
, McCue DA, Huang X,
Jabbour E
,
Garcia-Manero G
,
Estrov Z
,
Kantarjian HM
. Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Cancer. 2015 Dec 01; 121(23):4158-64.
PMID:
26308885
; PMCID:
PMC4666803
.
Citations:
61
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Jain P, Hu S,
Jabbour E
,
Takahashi K
,
Pemmaraju N
, O'Brien S,
Mulanovich VE
,
Estrov Z
. Disseminated histoplasmosis as pseudo Richter's transformation in a patient with chronic lymphocytic leukemia. Am J Hematol. 2015 Aug; 90(8):752-3.
PMID:
25850565
; PMCID:
PMC4509849
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Short NJ, Keating MJ,
Wierda WG
, Faderl S,
Ferrajoli A
,
Estrov Z
, Smith SC, O'Brien SM. Fludarabine, cyclophosphamide, and multiple-dose rituximab as frontline therapy for chronic lymphocytic leukemia. Cancer. 2015 Nov 01; 121(21):3869-76.
PMID:
26218678
; PMCID:
PMC4824541
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Thompson PA, O'Brien SM,
Wierda WG
,
Ferrajoli A
, Stingo F, Smith SC,
Burger JA
,
Estrov Z
,
Jain N
,
Kantarjian HM
, Keating MJ. Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib-based regimens. Cancer. 2015 Oct 15; 121(20):3612-21.
PMID:
26193999
; PMCID:
PMC4866653
.
Citations:
88
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ohanian M
,
Bueso-Ramos C
,
Ok CY
, Lin P, Patel K, Alattar ML,
Khoury JD
, Rozovski U,
Estrov Z
,
Huh YO
, Cortes J, Abruzzo LV. Acute myeloid leukemia with MYC rearrangement and JAK2 V617F mutation. Cancer Genet. 2015 Nov; 208(11):571-4.
PMID:
26382622
; PMCID:
PMC4835801
.
Citations:
2
Fields:
Gen
Genetics
Neo
Neoplasms
Translation:
Humans
Cells
Masarova L, Newberry KJ, Pierce SA,
Estrov Z
,
Cortes JE
,
Kantarjian HM
,
Verstovsek S
. Association of lymphoid malignancies and Philadelphia-chromosome negative myeloproliferative neoplasms: Clinical characteristics, therapy and outcome. Leuk Res. 2015 Aug; 39(8):822-7.
PMID:
26012362
; PMCID:
PMC4547830
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jain P,
Verstovsek S
,
Loghavi S
,
Jorgensen JL
,
Patel KP
,
Estrov Z
,
Fayad L
,
Pemmaraju N
. Durable remission with rituximab in a patient with an unusual variant of Castleman's disease with myelofibrosis-TAFRO syndrome. Am J Hematol. 2015 Nov; 90(11):1091-2.
PMID:
25808231
; PMCID:
PMC4580493
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Cells
Ferrajoli A
,
Ivan C
, Ciccone M, Shimizu M, Kita Y, Ohtsuka M, D'Abundo L, Qiang J, Lerner S, Nouraee N, Rabe KG, Rassenti LZ,
Van Roosbroeck K
,
Manning JT
, Yuan Y, Zhang X, Shanafelt TD,
Wierda WG
, Sabbioni S,
Tarrand JJ
,
Estrov Z
, Radovich M,
Liang H
, Negrini M, Kipps TJ, Kay NE, Keating M,
Calin GA
. Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival. EBioMedicine. 2015 Jun; 2(6):572-82.
PMID:
26288818
; PMCID:
PMC4535165
.
Citations:
26
Fields:
Gen
Genetics
Med
Medicine (General)
Translation:
Humans
Cells
Rozovski U, Benjamini O, Jain P,
Thompson PA
,
Wierda WG
, O'Brien S,
Burger JA
,
Ferrajoli A
, Faderl S,
Shpall E
,
Hosing C
,
Khouri IF
,
Champlin R
, Keating MJ,
Estrov Z
. Outcomes of Patients With Chronic Lymphocytic Leukemia and Richter's Transformation After Transplantation Failure. J Clin Oncol. 2015 May 10; 33(14):1557-63.
PMID:
25847930
; PMCID:
PMC4417727
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Kurzrock R,
Estrov Z
, Talpaz M,
Kantarjian HM
. Meir Wetzler, MD. Cancer. 2015 Jul 01; 121(13):2106-7.
PMID:
25832851
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Thompson PA, Rozovski U, Keating MJ, Stingo F, Smith SC,
Wierda WG
, Falchi L, O'Brien SM,
Estrov Z
,
Burger JA
,
Ferrajoli A
. The addition of CD20 monoclonal antibodies to lenalidomide improves response rates and survival in relapsed/refractory patients with chronic lymphocytic leukaemia relative to lenalidomide monotherapy - the MD Anderson Cancer Center experience. Br J Haematol. 2015 Oct; 171(2):281-284.
PMID:
25824652
; PMCID:
PMC4589497
.
Citations:
2
Fields:
Hem
Hematology
Jain P, Keating M,
Thompson PA
, Trinh L, Wang X,
Wierda W
,
Ferrajoli A
,
Burger J
,
Kantarjian H
,
Estrov Z
, Abruzzo L, O'Brien S. High fluorescence in situ hybridization percentage of deletion 11q in patients with chronic lymphocytic leukemia is an independent predictor of adverse outcome. Am J Hematol. 2015 Jun; 90(6):471-7.
PMID:
25683856
; PMCID:
PMC4521389
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
Cells
Rozovski U, Grgurevic S,
Bueso-Ramos C
, Harris DM, Li P, Liu Z, Wu JY, Jain P,
Wierda W
,
Burger J
, O'Brien S,
Jain N
,
Ferrajoli A
, Keating MJ,
Estrov Z
. Aberrant LPL Expression, Driven by STAT3, Mediates Free Fatty Acid Metabolism in CLL Cells. Mol Cancer Res. 2015 May; 13(5):944-53.
PMID:
25733697
; PMCID:
PMC4433415
.
Citations:
37
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Strati P,
Kantarjian H
, Ravandi F, Nazha A,
Borthakur G
,
Daver N
,
Kadia T
,
Estrov Z
,
Garcia-Manero G
,
Konopleva M
, Rajkhowa T, Durand M,
Andreeff M
, Levis M, Cortes J. Phase I/II trial of the combination of midostaurin (PKC412) and 5-azacytidine for patients with acute myeloid leukemia and myelodysplastic syndrome. Am J Hematol. 2015 Apr; 90(4):276-81.
PMID:
25530214
; PMCID:
PMC4376596
.
Citations:
61
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Jain P, Keating M,
Wierda W
,
Estrov Z
,
Ferrajoli A
,
Jain N
, George B, James D,
Kantarjian H
,
Burger J
, O'Brien S. Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib. Blood. 2015 Mar 26; 125(13):2062-7.
PMID:
25573991
; PMCID:
PMC4467871
.
Citations:
121
Fields:
Hem
Hematology
Translation:
Humans
Ohanian M
, Rozovski U, Ravandi F,
Garcia-Manero G
,
Jabbour E
,
Kantarjian HM
,
Estrov Z
. Very high levels of lactate dehydrogenase at diagnosis predict central nervous system relapse in acute promyelocytic leukaemia. Br J Haematol. 2015 May; 169(4):595-7.
PMID:
25413673
; PMCID:
PMC4414662
.
Citations:
2
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Benjamini O, Jain P, Trinh L, Qiao W, Strom SS, Lerner S, Wang X, Burger J,
Ferrajoli A
,
Kantarjian H
, O'Brien S,
Wierda W
,
Estrov Z
, Keating M. Second cancers in patients with chronic lymphocytic leukemia who received frontline fludarabine, cyclophosphamide and rituximab therapy: distribution and clinical outcomes. Leuk Lymphoma. 2015 Jun; 56(6):1643-50.
PMID:
25308294
; PMCID:
PMC4437921
.
Citations:
42
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Kadia TM
,
Kantarjian HM
, Thomas DA, O'Brien S,
Estrov Z
, Ravandi F,
Jabbour E
,
Pemmaraju N
,
Daver N
, Wang X, Jain P, Pierce S, Brandt M,
Garcia-Manero G
,
Cortes J
,
Borthakur G
. Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia. Am J Hematol. 2015 Feb; 90(2):120-4.
PMID:
25368968
; PMCID:
PMC4447180
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Rozovski U,
Ohanian M
, Ravandi F,
Garcia-Manero G
, Faderl S, Pierce S, Cortes J,
Estrov Z
. Incidence of and risk factors for involvement of the central nervous system in acute myeloid leukemia. Leuk Lymphoma. 2015 May; 56(5):1392-7.
PMID:
25110819
; PMCID:
PMC4417664
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Li J, Kurasawa Y, Wang Y, Clise-Dwyer K, Klumpp SA, Liang H,
Tailor RC
, Raymond AC,
Estrov Z
, Brandt SJ,
Davis RE
, Zweidler-McKay P,
Amin HM
, Nagarajan L. Requirement for ssbp2 in hematopoietic stem cell maintenance and stress response. J Immunol. 2014 Nov 01; 193(9):4654-62.
PMID:
25238756
; PMCID:
PMC4201964
.
Citations:
8
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Strati P,
Pemmaraju N
,
Estrov Z
, Cardenas-Turanzas M, Pierce S, Newberry KJ,
Daver N
,
Cortes J
,
Kantarjian H
,
Verstovsek S
. Clinical significance of microcytosis in patients with primary myelofibrosis. Leuk Res. 2014 Oct; 38(10):1212-6.
PMID:
25217891
; PMCID:
PMC4182146
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Chen Y,
Estrov Z
, Pierce S, Qiao W,
Borthakur G
, Ravandi F,
Kadia T
, Brandt M, O'Brien S,
Jabbour E
,
Garcia-Manero G
, Cortes J, Beran M. Myeloid neoplasms after breast cancer: "therapy-related" not an independent poor prognostic factor. Leuk Lymphoma. 2015 Apr; 56(4):1012-9.
PMID:
25048874
; PMCID:
PMC4326620
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Jain P,
Lee HJ
, Qiao W,
Wierda W
, Benjamini O,
Burger J
,
Ferrajoli A
,
Estrov Z
,
Kantarjian H
, Keating M, O'Brien S. FCR and bevacizumab treatment in patients with relapsed chronic lymphocytic leukemia. Cancer. 2014 Nov 15; 120(22):3494-501.
PMID:
25043749
; PMCID:
PMC4221361
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Jain P,
Ok CY
,
Konoplev S
,
Patel KP
,
Jorgensen J
,
Estrov Z
, Luthra R,
Kantarjian H
, Ravandi F. Relapsed Refractory BRAF-Negative, IGHV4-34-Positive Variant of Hairy Cell Leukemia: A Distinct Entity? J Clin Oncol. 2016 Mar 01; 34(7):e57-60.
PMID:
24982452
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Ohanian M
, Huang RS, Yakoushina TV,
Estrov Z
, Juneja H, Chen L, Idowu M, Abruzzo LV. Isolated mesenteric CD20-positive myeloid sarcoma. Clin Lymphoma Myeloma Leuk. 2014 Dec; 14(6):e217-20.
PMID:
25131853
; PMCID:
PMC4257057
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Li P, Harris D, Liu Z, Rozovski U,
Ferrajoli A
, Wang Y,
Bueso-Ramos C
, Hazan-Halevy I, Grgurevic S,
Wierda W
, Burger J, O'Brien S, Faderl S, Keating M,
Estrov Z
. STAT3-activated GM-CSFRa translocates to the nucleus and protects CLL cells from apoptosis. Mol Cancer Res. 2014 Sep; 12(9):1267-82.
PMID:
24836891
; PMCID:
PMC4163508
.
Citations:
11
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Daver N
, Kim H,
Dinardo C
,
Jabbour E
,
Kadia T
,
Borthakur G
, Pierce S, Shan J, Cardenas-Turanzas M,
Cortes J
, Ravandi F,
Wierda W
,
Estrov Z
, Faderl S,
Wei Y
,
Kantarjian H
,
Garcia-Manero G
, Quint?s-Cardama A. A prognostic model of therapy-related myelodysplastic syndrome for predicting survival and transformation to acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2014 Oct; 14(5):401-10.
PMID:
24875590
; PMCID:
PMC4167474
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Rozovski U,
Wu JY
, Harris DM, Liu Z, Li P, Hazan-Halevy I,
Ferrajoli A
,
Burger JA
, O'Brien S,
Jain N
,
Verstovsek S
,
Wierda WG
, Keating MJ,
Estrov Z
. Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells. Blood. 2014 Jun 12; 123(24):3797-802.
PMID:
24778152
; PMCID:
PMC4055926
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
Cells
Alvarado Y
,
Kantarjian HM
,
Luthra R
, Ravandi F,
Borthakur G
,
Garcia-Manero G
,
Konopleva M
,
Estrov Z
,
Andreeff M
,
Cortes JE
. Treatment with FLT3 inhibitor in patients with FLT3-mutated acute myeloid leukemia is associated with development of secondary FLT3-tyrosine kinase domain mutations. Cancer. 2014 Jul 15; 120(14):2142-9.
PMID:
24737502
; PMCID:
PMC4124083
.
Citations:
58
Fields:
Neo
Neoplasms
Translation:
Humans
Strati P, Keating MJ, O'Brien SM,
Burger J
,
Ferrajoli A
,
Jain N
,
Estrov Z
,
Jorgensen J
, Challagundla P, Faderl SH,
Wierda WG
, Tambaro FP. Eradication of bone marrow minimal residual disease may prompt early treatment discontinuation in CLL. Blood. 2014 Jun 12; 123(24):3727-32.
PMID:
24705492
; PMCID:
PMC4067501
.
Citations:
45
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Rozovski U, Li P, Harris D,
Ohanian M
,
Kantarjian H
,
Estrov Z
. Interleukin-7 receptor-a gene mutations are not detected in adult T-cell acute lymphoblastic leukemia. Cancer Med. 2014 Jun; 3(3):550-4.
PMID:
24678068
; PMCID:
PMC4101745
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Falchi L, Keating MJ, Marom EM,
Truong MT
,
Schlette EJ
, Sargent RL, Trinh L, Wang X, Smith SC,
Jain N
,
Estrov Z
, O'Brien S,
Wierda WG
, Lerner S,
Ferrajoli A
. Correlation between FDG/PET, histology, characteristics, and survival in 332 patients with chronic lymphoid leukemia. Blood. 2014 May 01; 123(18):2783-90.
PMID:
24615780
; PMCID:
PMC4123418
.
Citations:
38
Fields:
Hem
Hematology
Translation:
Humans
Chae YK, Trinh L, Jain P, Wang X, Rozovski U,
Wierda WG
, Keating MJ,
Estrov Z
. Statin and aspirin use is associated with improved outcome of FCR therapy in relapsed/refractory chronic lymphocytic leukemia. Blood. 2014 Feb 27; 123(9):1424-6.
PMID:
24578497
; PMCID:
PMC3938153
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
Ravandi F, Arana Yi C, Cortes JE, Levis M, Faderl S,
Garcia-Manero G
, Jabbour E,
Konopleva M
, O'Brien S,
Estrov Z
, Borthakur G, Thomas D, Pierce S, Brandt M, Pratz K, Luthra R,
Andreeff M
,
Kantarjian H
. Final report of phase II study of sorafenib, cytarabine and idarubicin for initial therapy in younger patients with acute myeloid leukemia. Leukemia. 2014 Jul; 28(7):1543-5.
PMID:
24487412
; PMCID:
PMC4091714
.
Citations:
38
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Strati P, Manning JT,
Ok CY
,
Garcia-Manero G
,
Estrov Z
. Interaction between myelomonocytic and lymphoid cells in a patient with acute myelomonocytic leukemia and chronic lymphocytic leukemia. Leuk Lymphoma. 2014 Jun; 55(6):1425-7.
PMID:
23987820
; PMCID:
PMC4204466
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Jain P, Baez-Vallecillo L,
Huh YO
, Benjamini O, Abruzzo L, O'Brien S,
Pemmaraju N
, Keating M,
Gagel RF
,
Estrov Z
. Atypical chronic lymphocytic leukemia with polyglandular autoimmune endocrinopathy type II: a complex profile. Leuk Lymphoma. 2014 Apr; 55(4):944-6.
PMID:
23829280
; PMCID:
PMC4102379
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Fiorcari S, Brown WS, McIntyre BW,
Estrov Z
, Maffei R, O'Brien S, Sivina M, Hoellenriegel J,
Wierda WG
, Keating MJ, Ding W, Kay NE, Lannutti BJ, Marasca R,
Burger JA
. The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells. PLoS One. 2013; 8(12):e83830.
PMID:
24376763
; PMCID:
PMC3871531
.
Citations:
43
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Grgurevic S, Rozovski U, Li P,
Estrov Z
,
Cortes J
, Quint?s-Cardama A. Detection of dormant chronic myeloid leukemia clones in the bone marrow of patients in complete molecular remission. Clin Lymphoma Myeloma Leuk. 2013 Dec; 13(6):681-5.
PMID:
24060288
; PMCID:
PMC4162086
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Nazha A,
Kantarjian H
, Ravandi F,
Huang X
, Choi S,
Garcia-Manero G
,
Jabbour E
,
Borthakur G
,
Kadia T
,
Konopleva M
,
Cortes J
,
Ferrajoli A
,
Kornblau S
,
Daver N
,
Pemmaraju N
,
Andreeff M
,
Estrov Z
, Du M, Brandt M, Faderl S. Clofarabine, idarubicin, and cytarabine (CIA) as frontline therapy for patients =60 years with newly diagnosed acute myeloid leukemia. Am J Hematol. 2013 Nov; 88(11):961-6.
PMID:
23877926
; PMCID:
PMC4110914
.
Citations:
21
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Rozovski U, Keating MJ,
Estrov Z
. Targeting inflammatory pathways in chronic lymphocytic leukemia. Crit Rev Oncol Hematol. 2013 Dec; 88(3):655-66.
PMID:
23941728
; PMCID:
PMC3844117
.
Citations:
17
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Irwin ME, Nelson LD, Santiago-O'Farrill JM, Knouse PD, Miller CP, Palla SL, Siwak DR,
Mills GB
,
Estrov Z
,
Li S
,
Kornblau SM
, Hughes DP,
Chandra J
. Small molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemia. PLoS One. 2013; 8(8):e70608.
PMID:
23936456
; PMCID:
PMC3731286
.
Citations:
13
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Jabbour E
,
Takahashi K
, Wang X, Cornelison AM, Abruzzo L,
Kadia T
,
Borthakur G
,
Estrov Z
, O'Brien S, Mallo M,
Wierda W
, Pierce S,
Wei Y
, Sole F, Chen R,
Kantarjian H
,
Garcia-Manero G
. Acquisition of cytogenetic abnormalities in patients with IPSS defined lower-risk myelodysplastic syndrome is associated with poor prognosis and transformation to acute myelogenous leukemia. Am J Hematol. 2013 Oct; 88(10):831-7.
PMID:
23760779
; PMCID:
PMC3923606
.
Citations:
21
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Rozovski U, Hazan-Halevy I, Keating MJ,
Estrov Z
. Personalized medicine in CLL: current status and future perspectives. Cancer Lett. 2014 Sep 28; 352(1):4-14.
PMID:
23879961
; PMCID:
PMC3871981
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Ravandi F,
Jorgensen JL
, Thomas DA, O'Brien S, Garris R, Faderl S,
Huang X
, Wen S,
Burger JA
,
Ferrajoli A
,
Kebriaei P
,
Champlin RE
,
Estrov Z
, Challagundla P, Wang SA,
Luthra R
,
Cortes JE
,
Kantarjian HM
. Detection of MRD may predict the outcome of patients with Philadelphia chromosome-positive ALL treated with tyrosine kinase inhibitors plus chemotherapy. Blood. 2013 Aug 15; 122(7):1214-21.
PMID:
23836561
; PMCID:
PMC3976223
.
Citations:
77
Fields:
Hem
Hematology
Translation:
Humans
Cells
Ferrajoli A
, Shanafelt TD,
Ivan C
, Shimizu M, Rabe KG, Nouraee N, Ikuo M, Ghosh AK, Lerner S, Rassenti LZ, Xiao L, Hu J, Reuben JM, Calin S, You MJ,
Manning JT
,
Wierda WG
,
Estrov Z
, O'Brien S, Kipps TJ, Keating MJ, Kay NE,
Calin GA
. Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia. Blood. 2013 Sep 12; 122(11):1891-9.
PMID:
23821659
; PMCID:
PMC3779381
.
Citations:
85
Fields:
Hem
Hematology
Translation:
Humans
Cells
Benjamini O, Jain P,
Konoplev SN
,
Yin CC
, Abruzzo L, Wotherspoon AC, Dearden C,
Shpall EJ
,
Estrov Z
, Keating MJ. CD4(-)/CD8(-) variant of T-cell large granular lymphocytic leukemia or hepatosplenic T-cell lymphoma: a clinicopathologic dilemma. Clin Lymphoma Myeloma Leuk. 2013 Oct; 13(5):610-3.
PMID:
23800602
; PMCID:
PMC4167023
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Abdel-Wahab O, Manshouri T, Kilpivaara O,
Cortes J
, Roupie AL, Zhang SJ, Harris D,
Estrov Z
,
Kantarjian H
, Levine RL,
Verstovsek S
, Quint?s-Cardama A. Molecular analysis of patients with polycythemia vera or essential thrombocythemia receiving pegylated interferon a-2a. Blood. 2013 Aug 08; 122(6):893-901.
PMID:
23782935
; PMCID:
PMC3739035
.
Citations:
87
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Takahashi K
, Jabbour E, Wang X, Luthra R,
Bueso-Ramos C
,
Patel K
, Pierce S,
Yang H
,
Wei Y
, Daver N, Faderl S, Ravandi F,
Estrov Z
,
Cortes J
,
Kantarjian H
,
Garcia-Manero G
. Dynamic acquisition of FLT3 or RAS alterations drive a subset of patients with lower risk MDS to secondary AML. Leukemia. 2013 Oct; 27(10):2081-3.
PMID:
23774633
.
Citations:
25
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Li P, Grgurevic S, Liu Z, Harris D, Rozovski U,
Calin GA
, Keating MJ,
Estrov Z
. Signal transducer and activator of transcription-3 induces microRNA-155 expression in chronic lymphocytic leukemia. PLoS One. 2013; 8(6):e64678.
PMID:
23750211
; PMCID:
PMC3672147
.
Citations:
21
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Garcia-Manero G
,
Jabbour E
,
Borthakur G
, Faderl S,
Estrov Z
,
Yang H
, Maddipoti S, Godley LA, Gabrail N, Berdeja JG, Nadeem A, Kassalow L,
Kantarjian H
. Randomized open-label phase II study of decitabine in patients with low- or intermediate-risk myelodysplastic syndromes. J Clin Oncol. 2013 Jul 10; 31(20):2548-53.
PMID:
23733767
; PMCID:
PMC4878053
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Rozovski U,
Calin GA
, Setoyama T, D'Abundo L, Harris DM, Li P, Liu Z, Grgurevic S,
Ferrajoli A
, Faderl S,
Burger JA
, O'Brien S,
Wierda WG
, Keating MJ,
Estrov Z
. Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells. Mol Cancer. 2013 Jun 01; 12:50.
PMID:
23725032
; PMCID:
PMC3671957
.
Citations:
37
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Daver N, Vega-Ruiz A,
Kantarjian HM
,
Estrov Z
,
Ferrajoli A
,
Kornblau S
,
Verstovsek S
,
Garcia-Manero G
, Cortes JE. A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome. Eur J Cancer Care (Engl). 2013 Sep; 22(5):605-11.
PMID:
23701251
; PMCID:
PMC3745781
.
Citations:
8
Fields:
Neo
Neoplasms
Nur
Nursing
Translation:
Humans
CT
Clinical Trials
Takahashi K
,
Kantarjian H
,
Pemmaraju N
,
Andreeff M
,
Borthakur G
, Faderl S,
Garcia-Manero G
, Pierce S,
Luthra R
, Cardenas-Turanzas M,
Estrov Z
, Ravandi F,
Cortes J
. Salvage therapy using FLT3 inhibitors may improve long-term outcome of relapsed or refractory AML in patients with FLT3-ITD. Br J Haematol. 2013 Jun; 161(5):659-666.
PMID:
23530930
; PMCID:
PMC4068703
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Cells
Al-Kali A,
Luthra R
,
Bueso-Ramos C
, Pierce S,
Kadia T
,
Borthakur G
,
Estrov Z
,
Jabbour E
, Faderl S, Ravandi F,
Cortes J
, Tefferi A,
Kantarjian H
,
Garcia-Manero G
, Quint?s-Cardama A. Prognostic impact of RAS mutations in patients with myelodysplastic syndrome. Am J Hematol. 2013 May; 88(5):365-9.
PMID:
23512829
; PMCID:
PMC4089101
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Jain P, Benjamini O,
Konoplev S
, Mohamed MS, Romo CG,
Estrov Z
. Spontaneous remission of chemo-immunotherapy related, non-transplant Epstein-Barr virus-associated lymphoproliferative disorder in a patient with chronic lymphocytic leukemia. Leuk Lymphoma. 2013 Nov; 54(11):2540-2.
PMID:
23387894
; PMCID:
PMC4103649
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Jain P, Benjamini O, Pei L,
Caraway NP
,
Landon G
, Kim S, Shivaprasad S,
Woodman K
, O'Brien S,
Ferrajoli A
,
Kadia T
,
Estrov Z
. Central nervous system Richter's transformation and parvovirus B19 infection. Leuk Lymphoma. 2013 Sep; 54(9):2070-2.
PMID:
23320889
; PMCID:
PMC4114215
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Nazha A,
Estrov Z
,
Cortes J
,
Bueso-Ramos CE
,
Kantarjian H
,
Verstovsek S
. Prognostic implications and clinical characteristics associated with bone marrow fibrosis in patients with myelofibrosis. Leuk Lymphoma. 2013 Nov; 54(11):2537-9.
PMID:
23343175
; PMCID:
PMC4135587
.
Citations:
6
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Ohanian M
, Faderl S, Ravandi F,
Pemmaraju N
,
Garcia-Manero G
,
Cortes J
,
Estrov Z
. Is acute myeloid leukemia a liquid tumor? Int J Cancer. 2013 Aug 01; 133(3):534-43.
PMID:
23280377
; PMCID:
PMC3904286
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Benjamini O, Jain P,
Schlette E
, Sciffman JS,
Estrov Z
, Keating M. Chronic lymphocytic leukemia with central nervous system involvement: a high-risk disease? Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):338-41.
PMID:
23332395
; PMCID:
PMC4167026
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Rozovski U, Keating M,
Estrov Z
. The significance of spliceosome mutations in chronic lymphocytic leukemia. Leuk Lymphoma. 2013 Jul; 54(7):1364-6.
PMID:
23270583
; PMCID:
PMC4176818
.
Citations:
8
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Malik A, Shoukier M,
Garcia-Manero G
,
Wierda W
,
Cortes J
, Bickel S, Keating MJ,
Estrov Z
. Azacitidine in fludarabine-refractory chronic lymphocytic leukemia: a phase II study. Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):292-5.
PMID:
23265768
; PMCID:
PMC3860181
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Bhamidipati PK,
Jabbour E
,
Konoplev S
,
Estrov Z
,
Cortes J
,
Daver N
. Epstein-Barr virus-induced CD30-positive diffuse large B-cell lymphoma in a patient with mixed-phenotypic leukemia treated with clofarabine. Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):342-6.
PMID:
23246163
; PMCID:
PMC4019340
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Lamothe B
, Lai Y, Hur L, Orozco NM, Wang J, Campos AD, Xie M,
Schneider MD
,
Lockworth CR
, Jakacky J, Tran D, Ho M, Dawud S, Dong C, Lin HK,
Hu P
,
Estrov Z
,
Bueso-Ramos CE
, Darnay BG. Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice. PLoS One. 2012; 7(12):e51228.
PMID:
23251462
; PMCID:
PMC3519594
.
Citations:
22
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Chen Y,
Kantarjian H
, Pierce S, Faderl S, O'Brien S, Qiao W, Abruzzo L, de Lima M,
Kebriaei P
, Jabbour E, Daver N, Kadia T,
Estrov Z
,
Garcia-Manero G
,
Cortes J
, Ravandi F. Prognostic significance of 11q23 aberrations in adult acute myeloid leukemia and the role of allogeneic stem cell transplantation. Leukemia. 2013 Apr; 27(4):836-42.
PMID:
23135353
; PMCID:
PMC4181539
.
Citations:
22
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Benjamini O, Jain P,
Estrov Z
,
Kantarjian HM
,
Verstovsek S
. Therapeutic effects of ruxolitinib in patients with myelofibrosis without clinically significant splenomegaly. Blood. 2012 Sep 27; 120(13):2768-9.
PMID:
23019204
; PMCID:
PMC4081400
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Ohanian M
,
Borthakur G
, Quintas-Cardama A, Mathisen M,
Estrov Z
,
Pemmaraju N
, Cort?s JE. Ocular granulocytic sarcoma: a case report and literature review of ocular extramedullary acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2013 Feb; 13(1):93-6.
PMID:
23017332
; PMCID:
PMC4151170
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A,
Estrov Z
, Ebert BL, Chiosis G, Nimer SD, Bernstein BE,
Verstovsek S
, Levine RL, G?nen M. Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy. Nature. 2012 Sep 06; 489(7414):155-9.
PMID:
22820254
; PMCID:
PMC3991463
.
Citations:
149
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Verstovsek S
,
Kantarjian HM
,
Estrov Z
,
Cortes JE
, Thomas DA,
Kadia T
, Pierce S,
Jabbour E
,
Borthakur G
, Rumi E, Pungolino E, Morra E, Caramazza D, Cazzola M, Passamonti F. Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls. Blood. 2012 Aug 09; 120(6):1202-9.
PMID:
22718840
; PMCID:
PMC4081158
.
Citations:
82
Fields:
Hem
Hematology
Translation:
Humans
Boumber Y,
Kantarjian H
,
Jorgensen J
, Wen S, Faderl S, Castoro R, Autry J,
Garcia-Manero G
, Borthakur G, Jabbour E,
Estrov Z
,
Cortes J
, Issa JP, Ravandi F. A randomized study of decitabine versus conventional care for maintenance therapy in patients with acute myeloid leukemia in complete remission. Leukemia. 2012 Nov; 26(11):2428-31.
PMID:
22665218
; PMCID:
PMC3981542
.
Citations:
20
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Chacar C,
Jabbour E
, Ravandi F,
Borthakur G
,
Kadia T
,
Estrov Z
, Rios MB,
Cortes J
,
Kantarjian H
. Phase I-II study of bendamustine in patients with acute leukemia and high risk myelodysplastic syndrome. Clin Lymphoma Myeloma Leuk. 2012 Jun; 12(3):197-200.
PMID:
22578814
; PMCID:
PMC4050633
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Chen Y,
Kantarjian H
,
Estrov Z
, Faderl S, Ravandi F, Rey K,
Cortes J
,
Borthakur G
. A phase II study of lenalidomide alone in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes with chromosome 5 abnormalities. Clin Lymphoma Myeloma Leuk. 2012 Oct; 12(5):341-4.
PMID:
22579233
; PMCID:
PMC4103411
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Kantarjian H
,
Estrov Z
,
Borthakur G
,
Cortes J
,
Verstovsek S
, Quint?s-Cardama A. Therapy with the histone deacetylase inhibitor pracinostat for patients with myelofibrosis. Leuk Res. 2012 Sep; 36(9):1124-7.
PMID:
22475363
; PMCID:
PMC4152772
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Eghtedar A,
Verstovsek S
,
Estrov Z
,
Burger J
,
Cortes J
, Bivins C, Faderl S,
Ferrajoli A
,
Borthakur G
, George S, Scherle PA, Newton RC,
Kantarjian HM
, Ravandi F. Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia. Blood. 2012 May 17; 119(20):4614-8.
PMID:
22422826
; PMCID:
PMC4081383
.
Citations:
85
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Ohanian M
, Leventaki V,
Verstovsek S
,
Estrov Z
,
Lin P
,
Yin C
,
Kantarjian H
,
Huh Y
, Ravandi F. Acute lymphoblastic leukemia arising in post-polycythemic myelofibrosis: a rare entity. Leuk Lymphoma. 2012 Sep; 53(9):1839-41.
PMID:
22303899
; PMCID:
PMC4120044
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Kadia TM
,
Borthakur G
,
Garcia-Manero G
, Faderl S,
Jabbour E
,
Estrov Z
, York S,
Huang X
, Pierce S, Brandt M, Koller C,
Kantarjian HM
, Ravandi F. Final results of the phase II study of rabbit anti-thymocyte globulin, ciclosporin, methylprednisone, and granulocyte colony-stimulating factor in patients with aplastic anaemia and myelodysplastic syndrome. Br J Haematol. 2012 May; 157(3):312-20.
PMID:
22360602
; PMCID:
PMC3924750
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Dimicoli S,
Jabbour E
,
Borthakur G
,
Kadia T
,
Estrov Z
,
Yang H
, Kelly M, Pierce S,
Kantarjian H
,
Garcia-Manero G
. Phase II study of the histone deacetylase inhibitor panobinostat (LBH589) in patients with low or intermediate-1 risk myelodysplastic syndrome. Am J Hematol. 2012 Jan; 87(1):127-9.
PMID:
22072492
; PMCID:
PMC4085038
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Naqvi K
,
Jabbour E
,
Bueso-Ramos C
, Pierce S,
Borthakur G
,
Estrov Z
, Ravandi F, Faderl S,
Kantarjian H
,
Garcia-Manero G
. Implications of discrepancy in morphologic diagnosis of myelodysplastic syndrome between referral and tertiary care centers. Blood. 2011 Oct 27; 118(17):4690-3.
PMID:
21868570
; PMCID:
PMC4081364
.
Citations:
30
Fields:
Hem
Hematology
Translation:
Humans
Faderl S,
Garcia-Manero G
,
Jabbour E
, Ravandi F,
Borthakur G
,
Estrov Z
,
Gandhi V
, Byrd AL, Kwari M,
Cortes J
,
Kantarjian HM
. A randomized study of 2 dose levels of intravenous clofarabine in the treatment of patients with higher-risk myelodysplastic syndrome. Cancer. 2012 Feb 01; 118(3):722-8.
PMID:
21751197
; PMCID:
PMC4180241
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Parikh SA, Keating MJ, O'Brien S, Wang X,
Ferrajoli A
, Faderl S, Burger J, Koller C,
Estrov Z
, Badoux X, Lerner S,
Wierda WG
. Frontline chemoimmunotherapy with fludarabine, cyclophosphamide, alemtuzumab, and rituximab for high-risk chronic lymphocytic leukemia. Blood. 2011 Aug 25; 118(8):2062-8.
PMID:
21750315
; PMCID:
PMC4081295
.
Citations:
27
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Badoux X,
Bueso-Ramos C
, Harris D, Li P, Liu Z,
Burger J
, O'Brien S,
Ferrajoli A
, Keating MJ,
Estrov Z
. Cross-talk between chronic lymphocytic leukemia cells and bone marrow endothelial cells: role of signal transducer and activator of transcription 3. Hum Pathol. 2011 Dec; 42(12):1989-2000.
PMID:
21733558
; PMCID:
PMC4085742
.
Citations:
11
Fields:
Pat
Pathology
Translation:
Humans
Cells
Harris DM, Hazan-Haley I, Coombes K,
Bueso-Ramos C
, Liu J, Liu Z, Li P, Ravoori M, Abruzzo L, Han L, Singh S, Sun M,
Kundra V
, Kurzrock R,
Estrov Z
. Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells. PLoS One. 2011; 6(6):e21250.
PMID:
21731684
; PMCID:
PMC3120836
.
Citations:
15
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Chen Y,
Cortes J
,
Estrov Z
, Faderl S, Qiao W, Abruzzo L,
Garcia-Manero G
, Pierce S,
Huang X
,
Kebriaei P
,
Kadia T
, De Lima M,
Kantarjian H
, Ravandi F. Persistence of cytogenetic abnormalities at complete remission after induction in patients with acute myeloid leukemia: prognostic significance and the potential role of allogeneic stem-cell transplantation. J Clin Oncol. 2011 Jun 20; 29(18):2507-13.
PMID:
21555694
; PMCID:
PMC4874214
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Manshouri T,
Estrov Z
,
Burger J
, Zhang Y, Livun A, Knez L, Harris D,
Creighton CJ
,
Kantarjian HM
,
Verstovsek S
, Quint?s-Cardama A. Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor. Cancer Res. 2011 Jun 01; 71(11):3831-40.
PMID:
21512135
; PMCID:
PMC4067142
.
Citations:
49
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Mesa RA,
Kantarjian H
, Tefferi A, Dueck A, Levy R, Vaddi K, Erickson-Viitanen S, Thomas DA,
Cortes J
,
Borthakur G
, Pardanani AD,
Estrov Z
,
Verstovsek S
. Evaluating the serial use of the Myelofibrosis Symptom Assessment Form for measuring symptomatic improvement: performance in 87 myelofibrosis patients on a JAK1 and JAK2 inhibitor (INCB018424) clinical trial. Cancer. 2011 Nov 01; 117(21):4869-4877.
PMID:
21480207
; PMCID:
PMC4160798
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Liu Z, Hazan-Halevy I, Harris DM, Li P,
Ferrajoli A
, Faderl S, Keating MJ,
Estrov Z
. STAT-3 activates NF-kappaB in chronic lymphocytic leukemia cells. Mol Cancer Res. 2011 Apr; 9(4):507-15.
PMID:
21364020
; PMCID:
PMC4212696
.
Citations:
31
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Lee BN, Gao H, Cohen EN, Badoux X,
Wierda WG
,
Estrov Z
, Faderl SH, Keating MJ,
Ferrajoli A
, Reuben JM. Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia. Cancer. 2011 Sep 01; 117(17):3999-4008.
PMID:
21858802
; PMCID:
PMC4349201
.
Citations:
40
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Jabbour E
,
Kantarjian H
, Ravandi F,
Garcia-Manero G
,
Estrov Z
,
Verstovsek S
, O'Brien S, Faderl S, Thomas DA, Wright JJ,
Cortes J
. A phase 1-2 study of a farnesyltransferase inhibitor, tipifarnib, combined with idarubicin and cytarabine for patients with newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndrome. Cancer. 2011 Mar 15; 117(6):1236-44.
PMID:
20960519
; PMCID:
PMC4061136
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Ma W,
Kantarjian H
, Zhang X, Wang X,
Estrov Z
, O'Brien S, Albitar M. Ubiquitin-proteasome system profiling in acute leukemias and its clinical relevance. Leuk Res. 2011 Apr; 35(4):526-33.
PMID:
20951430
; PMCID:
PMC4051750
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Verstovsek S
,
Kantarjian H
, Mesa RA, Pardanani AD, Cortes-Franco J, Thomas DA,
Estrov Z
, Fridman JS, Bradley EC, Erickson-Viitanen S, Vaddi K, Levy R, Tefferi A. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med. 2010 Sep 16; 363(12):1117-27.
PMID:
20843246
; PMCID:
PMC5187954
.
Citations:
489
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Tong WG,
Wierda WG
, Lin E, Kuang SQ, Bekele BN,
Estrov Z
,
Wei Y
,
Yang H
, Keating MJ,
Garcia-Manero G
. Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics. 2010 Aug 16; 5(6):499-508.
PMID:
20484983
; PMCID:
PMC3322493
.
Citations:
53
Fields:
Gen
Genetics
Translation:
Humans
Cells
Kornblau SM
, McCue D, Singh N, Chen W,
Estrov Z
, Coombes KR. Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia. Blood. 2010 Nov 18; 116(20):4251-61.
PMID:
20679526
; PMCID:
PMC4081283
.
Citations:
65
Fields:
Hem
Hematology
Translation:
Humans
Li P, Harris D, Liu Z, Liu J, Keating M,
Estrov Z
. Stat3 activates the receptor tyrosine kinase like orphan receptor-1 gene in chronic lymphocytic leukemia cells. PLoS One. 2010 Jul 29; 5(7):e11859.
PMID:
20686606
; PMCID:
PMC2912280
.
Citations:
38
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Tong WG,
Estrov Z
, Wang Y, O'Brien S, Faderl S, Harris DM, Van Pham Q, Hazan-Halevy I, Liu Z, Koch P,
Kantarjian H
, Keating MJ,
Ferrajoli A
. The synthetic heat shock protein 90 (Hsp90) inhibitor EC141 induces degradation of Bcr-Abl p190 protein and apoptosis of Ph-positive acute lymphoblastic leukemia cells. Invest New Drugs. 2011 Dec; 29(6):1206-12.
PMID:
20533075
; PMCID:
PMC4230707
.
Citations:
7
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
Cells
Faderl S,
Bueso-Ramos C
, Liu Z, Pal A,
Bornmann W
, Ciurea DV, Harris D, Hazan-Halevy I,
Kantarjian HM
,
Estrov Z
. Kit inhibitor APcK110 extends survival in an AML xenograft mouse model. Invest New Drugs. 2011 Oct; 29(5):1094-7.
PMID:
20517635
; PMCID:
PMC4251765
.
Citations:
3
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
Animals
Cells
Verma D,
Kantarjian H
, Shan J, O'Brien S,
Estrov Z
,
Garcia-Manero G
, Koller C,
Borthakur G
,
Cortes J
. Survival outcomes for clonal evolution in chronic myeloid leukemia patients on second generation tyrosine kinase inhibitor therapy. Cancer. 2010 Jun 01; 116(11):2673-81.
PMID:
20499401
; PMCID:
PMC4216809
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Liu X
, Wang Y, Benaissa S, Matsuda A,
Kantarjian H
,
Estrov Z
, Plunkett W. Homologous recombination as a resistance mechanism to replication-induced double-strand breaks caused by the antileukemia agent CNDAC. Blood. 2010 Sep 09; 116(10):1737-46.
PMID:
20479284
; PMCID:
PMC2947394
.
Citations:
16
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Faderl S,
Garcia-Manero G
,
Estrov Z
, Ravandi F,
Borthakur G
,
Cortes JE
, O'Brien S,
Gandhi V
, Plunkett W, Byrd A, Kwari M,
Kantarjian HM
. Oral clofarabine in the treatment of patients with higher-risk myelodysplastic syndrome. J Clin Oncol. 2010 Jun 01; 28(16):2755-60.
PMID:
20421540
; PMCID:
PMC4872315
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Manshouri T,
Estrov Z
, Harris D, Zhang Y,
Gaikwad A
,
Kantarjian HM
,
Verstovsek S
, Quint?s-Cardama A. Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor. Invest New Drugs. 2011 Oct; 29(5):818-26.
PMID:
20372971
; PMCID:
PMC4170651
.
Citations:
11
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
Animals
Cells
Bruey JM,
Kantarjian H
, Ma W,
Estrov Z
, Yeh C, Donahue A, Sanders H, O'Brien S, Keating M, Albitar M. Circulating Ki-67 index in plasma as a biomarker and prognostic indicator in chronic lymphocytic leukemia. Leuk Res. 2010 Oct; 34(10):1320-4.
PMID:
20362333
; PMCID:
PMC4108997
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Wang Y, Klumpp S,
Amin HM
, Liang H, Li J,
Estrov Z
, Zweidler-McKay P, Brandt SJ, Agulnick A, Nagarajan L. SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability. Oncogene. 2010 May 27; 29(21):3044-53.
PMID:
20348955
; PMCID:
PMC2878399
.
Citations:
20
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ravandi F,
Cortes JE
, Jones D, Faderl S,
Garcia-Manero G
,
Konopleva MY
, O'Brien S,
Estrov Z
,
Borthakur G
, Thomas D, Pierce SR, Brandt M, Byrd A, Bekele BN, Pratz K,
Luthra R
, Levis M,
Andreeff M
,
Kantarjian HM
. Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia. J Clin Oncol. 2010 Apr 10; 28(11):1856-62.
PMID:
20212254
; PMCID:
PMC2930809
.
Citations:
154
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Hazan-Halevy I, Harris D, Liu Z, Liu J, Li P, Chen X, Shanker S,
Ferrajoli A
, Keating MJ,
Estrov Z
. STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells. Blood. 2010 Apr 08; 115(14):2852-63.
PMID:
20154216
; PMCID:
PMC2918366
.
Citations:
113
Fields:
Hem
Hematology
Translation:
Humans
Cells
Estrov Z
. The leukemia stem cell. Cancer Treat Res. 2010; 145:1-17.
PMID:
20306242
.
Citations:
2
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Santos FP,
Kantarjian HM
,
Jain N
, Manshouri T, Thomas DA,
Garcia-Manero G
, Kennedy D,
Estrov Z
,
Cortes J
,
Verstovsek S
. Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. Blood. 2010 Feb 11; 115(6):1131-6.
PMID:
20008298
; PMCID:
PMC4081385
.
Citations:
78
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kantarjian H
, Manshouri T,
Luthra R
,
Estrov Z
, Pierce S, Richie MA,
Borthakur G
,
Konopleva M
,
Cortes J
,
Verstovsek S
, Quint?s-Cardama A. Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera. J Clin Oncol. 2009 Nov 10; 27(32):5418-24.
PMID:
19826111
; PMCID:
PMC4881362
.
Citations:
126
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Yeh CH, Tseng R, Hannah A,
Estrov Z
, Estey E,
Kantarjian H
, Albitar M. Clinical correlation of circulating heat shock protein 70 in acute leukemia. Leuk Res. 2010 May; 34(5):605-9.
PMID:
19800118
; PMCID:
PMC4127889
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Kurtova AV,
Balakrishnan K
,
Chen R
, Ding W, Schnabl S, Quiroga MP, Sivina M,
Wierda WG
,
Estrov Z
, Keating MJ, Shehata M,
Gandhi V
, Kay NE, Plunkett W,
Burger JA
, J?ger U. Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance. Blood. 2009 Nov 12; 114(20):4441-50.
PMID:
19762485
; PMCID:
PMC4081374
.
Citations:
151
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Garg RJ,
Kantarjian H
, O'Brien S, Faderl S,
Estrov Z
,
Cortes J
, Quint?s-Cardama A. The use of nilotinib or dasatinib after failure to 2 prior tyrosine kinase inhibitors: long-term follow-up. Blood. 2009 Nov 12; 114(20):4361-8.
PMID:
19729517
; PMCID:
PMC3952810
.
Citations:
49
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Sever M,
Kantarjian H
, Pierce S,
Jain N
,
Estrov Z
,
Cortes J
,
Verstovsek S
. Cytogenetic abnormalities in essential thrombocythemia at presentation and transformation. Int J Hematol. 2009 Nov; 90(4):522-525.
PMID:
19728024
; PMCID:
PMC4209590
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Bruey JM,
Kantarjian H
,
Estrov Z
, Zhang Z, Ma W, Albitar F, Abdool A, Thomas D, Yeh C, O'Brien S, Albitar M. Circulating Ki-67 protein in plasma as a biomarker and prognostic indicator of acute lymphoblastic leukemia. Leuk Res. 2010 Feb; 34(2):173-6.
PMID:
19679351
; PMCID:
PMC4132892
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Carter BZ, Mak DH, Woessner R, Gross S, Schober WD,
Estrov Z
,
Kantarjian H
,
Andreeff M
. Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells. Leukemia. 2009 Oct; 23(10):1755-62.
PMID:
19458629
; PMCID:
PMC3593228
.
Citations:
13
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ma W,
Kantarjian H
, Bekele B, Donahue AC, Zhang X, Zhang ZJ, O'Brien S, Estey E,
Estrov Z
,
Cortes J
, Keating M, Giles F, Albitar M. Proteasome enzymatic activities in plasma as risk stratification of patients with acute myeloid leukemia and advanced-stage myelodysplastic syndrome. Clin Cancer Res. 2009 Jun 01; 15(11):3820-6.
PMID:
19458051
; PMCID:
PMC4091712
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Raza A, Galili N, Callander N, Ochoa L, Piro L, Emanuel P, Williams S, Burris H, Faderl S,
Estrov Z
, Curtin P, Larson RA, Keck JG, Jones M, Meng L, Brown GL. Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome. J Hematol Oncol. 2009 May 13; 2:20.
PMID:
19439093
; PMCID:
PMC2694211
.
Citations:
19
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Faderl S, Pal A,
Bornmann W
, Albitar M, Maxwell D, Van Q, Peng Z, Harris D, Liu Z, Hazan-Halevy I,
Kantarjian HM
,
Estrov Z
. Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer Res. 2009 May 01; 69(9):3910-7.
PMID:
19383925
; PMCID:
PMC4220548
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Vega-Ruiz A, Faderl S,
Estrov Z
, Pierce S,
Cortes J
,
Kantarjian H
, Ravandi F. Incidence of extramedullary disease in patients with acute promyelocytic leukemia: a single-institution experience. Int J Hematol. 2009 May; 89(4):489-496.
PMID:
19340529
; PMCID:
PMC4199302
.
Citations:
24
Fields:
Hem
Hematology
Translation:
Humans
Estrov Z
. Stem cells and somatic cells: reprogramming and plasticity. Clin Lymphoma Myeloma. 2009; 9 Suppl 3:S319-28.
PMID:
19778860
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ravandi F, Estey E, Jones D, Faderl S, O'Brien S, Fiorentino J, Pierce S, Blamble D,
Estrov Z
,
Wierda W
,
Ferrajoli A
,
Verstovsek S
,
Garcia-Manero G
,
Cortes J
,
Kantarjian H
. Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin. J Clin Oncol. 2009 Feb 01; 27(4):504-10.
PMID:
19075265
; PMCID:
PMC4881307
.
Citations:
119
Fields:
Neo
Neoplasms
Translation:
Humans
Faderl S,
Ferrajoli A
,
Wierda W
,
Huang X
,
Verstovsek S
, Ravandi F,
Estrov Z
,
Borthakur G
, Kwari M,
Kantarjian HM
. Clofarabine combinations as acute myeloid leukemia salvage therapy. Cancer. 2008 Oct 15; 113(8):2090-6.
PMID:
18756533
; PMCID:
PMC4163782
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Yeh CH, Tseng R, Zhang Z,
Cortes J
, O'Brien S, Giles F, Hannah A,
Estrov Z
, Keating M,
Kantarjian H
, Albitar M. Circulating heat shock protein 70 and progression in patients with chronic myeloid leukemia. Leuk Res. 2009 Feb; 33(2):212-7.
PMID:
18715642
; PMCID:
PMC4163801
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Borthakur G
,
Alvarado Y
,
Ravandi-Kashani F
,
Cortes J
,
Estrov Z
, Faderl S, Ivy P,
Bueso-Ramos C
, Nebiyou Bekele B, Giles F. Phase 1 study of XL119, a rebeccamycin analog, in patients with refractory hematologic malignancies. Cancer. 2008 Jul 15; 113(2):360-6.
PMID:
18473351
; PMCID:
PMC4126069
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Faderl S, Ravandi F,
Huang X
,
Garcia-Manero G
,
Ferrajoli A
,
Estrov Z
,
Borthakur G
,
Verstovsek S
, Thomas DA, Kwari M,
Kantarjian HM
. A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome. Blood. 2008 Sep 01; 112(5):1638-45.
PMID:
18565853
; PMCID:
PMC4081352
.
Citations:
67
Fields:
Hem
Hematology
Translation:
Humans
Manshouri T, Nussenzveig RH,
Gaikwad A
,
Estrov Z
, Prchal J,
Cortes JE
,
Kantarjian HM
,
Verstovsek S
, Quint?s-Cardama A. The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation. Cancer Sci. 2008 Jun; 99(6):1265-73.
PMID:
18482053
; PMCID:
PMC4829954
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Garcia-Manero G
, Assouline S,
Cortes J
,
Estrov Z
,
Kantarjian H
,
Yang H
, Newsome WM, Miller WH, Rousseau C, Kalita A, Bonfils C, Dubay M, Patterson TA, Li Z, Besterman JM, Reid G, Laille E, Martell RE, Minden M. Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia. Blood. 2008 Aug 15; 112(4):981-9.
PMID:
18495956
; PMCID:
PMC4081529
.
Citations:
102
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Konopleva M
, Watt J, Contractor R, Tsao T, Harris D,
Estrov Z
,
Bornmann W
,
Kantarjian H
, Viallet J, Samudio I,
Andreeff M
. Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax). Cancer Res. 2008 May 01; 68(9):3413-20.
PMID:
18451169
; PMCID:
PMC4096127
.
Citations:
117
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ma W,
Kantarjian H
, O'Brien S, Jilani I, Zhang X,
Estrov Z
,
Ferrajoli A
, Keating M, Giles F, Albitar M. Enzymatic activity of circulating proteasomes correlates with clinical behavior in patients with chronic lymphocytic leukemia. Cancer. 2008 Mar 15; 112(6):1306-12.
PMID:
18224667
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ferrajoli A
, Lee BN,
Schlette EJ
, O'Brien SM, Gao H, Wen S,
Wierda WG
,
Estrov Z
, Faderl S, Cohen EN, Li C, Reuben JM, Keating MJ. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood. 2008 Jun 01; 111(11):5291-7.
PMID:
18334676
; PMCID:
PMC4082321
.
Citations:
147
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Sun M,
Estrov Z
, Ji Y, Coombes KR, Harris DH, Kurzrock R. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol Cancer Ther. 2008 Mar; 7(3):464-73.
PMID:
18347134
.
Citations:
152
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
Verstovsek S
, Manshouri T, Harris D,
Cortes J
, Giles FJ,
Kantarjian H
,
Priebe W
,
Estrov Z
, Quint?s-Cardama A. WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation. Clin Cancer Res. 2008 Feb 01; 14(3):788-96.
PMID:
18245540
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Zhang W
,
Konopleva M
, Shi YX, McQueen T, Harris D, Ling X,
Estrov Z
, Small D,
Cortes J
,
Andreeff M
, Quint?s-Cardama A. Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia. J Natl Cancer Inst. 2008 Feb 06; 100(3):184-98.
PMID:
18230792
.
Citations:
159
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
CT
Clinical Trials
Tsimberidou AM
,
Wierda WG
, Plunkett W, Kurzrock R, O'Brien S, Wen S,
Ferrajoli A
,
Ravandi-Kashani F
,
Garcia-Manero G
,
Estrov Z
, Kipps TJ, Brown JR, Fiorentino A, Lerner S,
Kantarjian HM
, Keating MJ. Phase I-II study of oxaliplatin, fludarabine, cytarabine, and rituximab combination therapy in patients with Richter's syndrome or fludarabine-refractory chronic lymphocytic leukemia. J Clin Oncol. 2008 Jan 10; 26(2):196-203.
PMID:
18182662
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Jilani I, Wei C, Bekele BN, Zhang ZJ, Keating M,
Wierda W
,
Ferrajoli A
,
Estrov Z
,
Kantarjian H
, O'Brien SM, Giles FJ, Albitar M. Soluble syndecan-1 (sCD138) as a prognostic factor independent of mutation status in patients with chronic lymphocytic leukemia. Int J Lab Hematol. 2009 Feb; 31(1):97-105.
PMID:
18190591
; PMCID:
PMC4163781
.
Citations:
10
Fields:
Hem
Hematology
Translation:
Humans
Ferrajoli A
, Faderl S, Van Q, Koch P, Harris D, Liu Z, Hazan-Halevy I, Wang Y,
Kantarjian HM
,
Priebe W
,
Estrov Z
. WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells. Cancer Res. 2007 Dec 01; 67(23):11291-9.
PMID:
18056455
.
Citations:
63
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Aribi A,
Bueso-Ramos C
, Estey E,
Estrov Z
, O'Brien S, Giles F, Faderl S, Thomas D,
Kebriaei P
,
Garcia-Manero G
, Pierce S,
Cortes J
,
Kantarjian H
, Ravandi F. Biphenotypic acute leukaemia: a case series. Br J Haematol. 2007 Jul; 138(2):213-6.
PMID:
17593028
.
Citations:
15
Fields:
Hem
Hematology
Translation:
Humans
Soriano AO,
Yang H
, Faderl S,
Estrov Z
, Giles F, Ravandi F,
Cortes J
,
Wierda WG
, Ouzounian S, Quezada A, Pierce S, Estey EH, Issa JP,
Kantarjian HM
,
Garcia-Manero G
. Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome. Blood. 2007 Oct 01; 110(7):2302-8.
PMID:
17596541
.
Citations:
146
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Kornblau SM
, Banker DE, Stirewalt D, Shen D, Lemker E,
Verstovsek S
,
Estrov Z
, Faderl S,
Cortes J
, Beran M, Jackson CE, Chen W, Estey E, Appelbaum FR. Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study. Blood. 2007 Apr 01; 109(7):2999-3006.
PMID:
17158228
; PMCID:
PMC1852228
.
Citations:
44
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Kantarjian H
,
Garcia-Manero G
, O'Brien S, Faderl S,
Estrov Z
, Giles F, Murgo A, Ladie N,
Verstovsek S
,
Cortes J
, Quint?s-Cardama A. Phase I/II study of subcutaneous homoharringtonine in patients with chronic myeloid leukemia who have failed prior therapy. Cancer. 2007 Jan 15; 109(2):248-55.
PMID:
17154172
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Bartholomeusz GA
, Talpaz M, Kapuria V, Kong LY, Wang S,
Estrov Z
,
Priebe W
,
Wu J
, Donato NJ. Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells. Blood. 2007 Apr 15; 109(8):3470-8.
PMID:
17202319
; PMCID:
PMC1852235
.
Citations:
40
Fields:
Hem
Hematology
Translation:
Animals
Cells
Kornblau SM
, Qiu YH, Bekele BN, Cade JS, Zhou X, Harris D, Jackson CE,
Estrov Z
,
Andreeff M
. Studying the right cell in acute myelogenous leukemia: dynamic changes of apoptosis and signal transduction pathway protein expression in chemotherapy resistant ex-vivo selected "survivor cells". Cell Cycle. 2006 Dec; 5(23):2769-77.
PMID:
17172852
.
Citations:
7
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Ferrajoli A
, Faderl S, Ravandi F,
Estrov Z
. The JAK-STAT pathway: a therapeutic target in hematological malignancies. Curr Cancer Drug Targets. 2006 Dec; 6(8):671-9.
PMID:
17168672
.
Citations:
28
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Konopleva M
, Contractor R, Tsao T, Samudio I,
Ruvolo PP
, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M,
Estrov Z
, McCubrey J, May WS, Reed JC,
Andreeff M
. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell. 2006 Nov; 10(5):375-88.
PMID:
17097560
.
Citations:
476
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Reuben JM, Gao H, Lee BN, Harris DM, Cogdell D, Giralt SA,
Khouri IF
,
Saliba RM
,
Champlin RE
, Zhang W,
Estrov Z
, K?rbling M. Recombinant human granulocyte-colony-stimulating factor-mobilized and apheresis-collected endothelial progenitor cells: a novel blood cell component for therapeutic vasculogenesis. Transfusion. 2006 Oct; 46(10):1795-802.
PMID:
17002637
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Lev EI,
Estrov Z
, Aboulfatova K, Harris D, Granada JF, Alviar C,
Kleiman NS
, Dong JF. Potential role of activated platelets in homing of human endothelial progenitor cells to subendothelial matrix. Thromb Haemost. 2006 Oct; 96(4):498-504.
PMID:
17003929
.
Citations:
22
Fields:
Hem
Hematology
Vas
Vascular Diseases
Translation:
Humans
Cells
Montero AJ,
Estrov Z
, Freireich EJ,
Khouri IF
, Koller CA, Kurzrock R. Phase II study of low-dose interleukin-11 in patients with myelodysplastic syndrome. Leuk Lymphoma. 2006 Oct; 47(10):2049-54.
PMID:
17071475
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Kantarjian H
,
Oki Y
,
Garcia-Manero G
,
Huang X
, O'Brien S,
Cortes J
, Faderl S,
Bueso-Ramos C
, Ravandi F,
Estrov Z
,
Ferrajoli A
,
Wierda W
, Shan J, Davis J, Giles F, Saba HI, Issa JP. Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood. 2007 Jan 01; 109(1):52-7.
PMID:
16882708
.
Citations:
243
Fields:
Hem
Hematology
Translation:
Humans
Cells
Kurzrock R, Talpaz M, Li L,
Estrov Z
. Distinct biological impact of dephosphorylation vs. downregulation of p210Bcr-Abl: implications for imatinib mesylate response and resistance. Leuk Lymphoma. 2006 Aug; 47(8):1651-64.
PMID:
16966279
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Garcia-Manero G
,
Kantarjian HM
, Sanchez-Gonzalez B,
Yang H
, Rosner G,
Verstovsek S
,
Rytting M
,
Wierda WG
, Ravandi F, Koller C, Xiao L, Faderl S,
Estrov Z
,
Cortes J
, O'brien S, Estey E,
Bueso-Ramos C
, Fiorentino J,
Jabbour E
, Issa JP. Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia. Blood. 2006 Nov 15; 108(10):3271-9.
PMID:
16882711
; PMCID:
PMC1895437
.
Citations:
180
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Faderl S,
Ferrajoli A
, Harris D, Van Q,
Kantarjian HM
,
Estrov Z
. Atiprimod blocks phosphorylation of JAK-STAT and inhibits proliferation of acute myeloid leukemia (AML) cells. Leuk Res. 2007 Jan; 31(1):91-5.
PMID:
16828865
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Zeng Z
, Samudio IJ,
Zhang W
,
Estrov Z
, Harris D, Frolova O, Hail N, Chen W,
Kornblau SM
, Huang P,
Lu Y
,
Mills GB
,
Andreeff M
,
Konopleva M
,
Pelicano H
. Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia. Cancer Res. 2006 Apr 01; 66(7):3737-46.
PMID:
16585200
.
Citations:
42
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Carter BZ
, Mak DH, Schober WD, McQueen T, Harris D,
Estrov Z
, Evans RL,
Andreeff M
. Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells. Blood. 2006 Jul 15; 108(2):630-7.
PMID:
16556893
; PMCID:
PMC1895484
.
Citations:
59
Fields:
Hem
Hematology
Translation:
Humans
Cells
Koller C, Bekele BN, Zhou X, Park C,
Estrov Z
, O'Brien S, Keating M, Jilani I, Giles FJ,
Kantarjian HM
, Albitar M. Plasma thrombopoietin compared with immunoglobulin heavy-chain mutation status as a predictor of survival in chronic lymphocytic leukemia. Blood. 2006 Aug 01; 108(3):1001-6.
PMID:
16551975
.
Citations:
4
Fields:
Hem
Hematology
Translation:
Humans
Ravandi F,
Estrov Z
. Eradication of leukemia stem cells as a new goal of therapy in leukemia. Clin Cancer Res. 2006 Jan 15; 12(2):340-4.
PMID:
16428470
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Faderl S,
Verstovsek S
,
Cortes J
, Ravandi F, Beran M,
Garcia-Manero G
,
Ferrajoli A
,
Estrov Z
, O'Brien S, Koller C, Giles FJ,
Wierda W
, Kwari M,
Kantarjian HM
. Clofarabine and cytarabine combination as induction therapy for acute myeloid leukemia (AML) in patients 50 years of age or older. Blood. 2006 Jul 01; 108(1):45-51.
PMID:
16403905
.
Citations:
40
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Zhou Y, Garcia-Prieto C, Carney DA, Xu RH,
Pelicano H
, Kang Y, Yu W, Lou C, Kondo S,
Liu J
, Harris DM,
Estrov Z
, Keating MJ, Jin Z, Huang P. OSW-1: a natural compound with potent anticancer activity and a novel mechanism of action. J Natl Cancer Inst. 2005 Dec 07; 97(23):1781-5.
PMID:
16333034
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Giles FJ, Bellamy WT,
Estrov Z
, O'Brien SM,
Verstovsek S
, Ravandi F, Beran M, Bycott P, Pithavala Y, Steinfeldt H, Reich SD, List AF, Yee KW. The anti-angiogenesis agent, AG-013736, has minimal activity in elderly patients with poor prognosis acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Leuk Res. 2006 Jul; 30(7):801-11.
PMID:
16332390
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Sampath D,
Cortes J
,
Estrov Z
, Du M, Shi Z,
Andreeff M
,
Gandhi V
, Plunkett W. Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial. Blood. 2006 Mar 15; 107(6):2517-24.
PMID:
16293603
; PMCID:
PMC1895741
.
Citations:
54
Fields:
Hem
Hematology
Translation:
Humans
Cells
CT
Clinical Trials
Chandra J
, Tracy J, Loegering D, Flatten K,
Verstovsek S
, Beran M, Gorre M,
Estrov Z
, Donato N, Talpaz M, Sawyers C,
Bhalla K
, Karp J, Sausville E, Kaufmann SH. Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance. Blood. 2006 Mar 15; 107(6):2501-6.
PMID:
16291594
; PMCID:
PMC1895739
.
Citations:
31
Fields:
Hem
Hematology
Translation:
Humans
Cells
Medeiros LJ
,
Estrov Z
, Rassidakis GZ. Z-138 cell line was derived from a patient with blastoid variant mantle cell lymphoma. Leuk Res. 2006 Apr; 30(4):497-501.
PMID:
16203034
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Verstovsek S
, Golemovic M,
Kantarjian H
, Manshouri T,
Estrov Z
, Manley P, Sun T, Arlinghaus RB, Alland L, Dugan M,
Cortes J
, Giles F, Beran M. AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells. Cancer. 2005 Sep 15; 104(6):1230-6.
PMID:
16078266
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Lev EI,
Kleiman NS
,
Birnbaum Y
, Harris D,
Korbling M
,
Estrov Z
. Circulating endothelial progenitor cells and coronary collaterals in patients with non-ST segment elevation myocardial infarction. J Vasc Res. 2005 Sep-Oct; 42(5):408-14.
PMID:
16088214
.
Citations:
17
Fields:
Vas
Vascular Diseases
Translation:
Humans
Cells
Amit-Vazina M, Shishodia S, Harris D, Van Q,
Wang M
,
Weber D
, Alexanian R, Talpaz M, Aggarwal BB,
Estrov Z
. Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells. Br J Cancer. 2005 Jul 11; 93(1):70-80.
PMID:
15970928
; PMCID:
PMC2361492
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Faderl S,
Ferrajoli A
, Harris D, Van Q,
Priebe W
,
Estrov Z
. WP-1034, a novel JAK-STAT inhibitor, with proapoptotic and antileukemic activity in acute myeloid leukemia (AML). Anticancer Res. 2005 May-Jun; 25(3B):1841-50.
PMID:
16158916
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Freireich EJ, Kurzrock R,
Estrov Z
. Metastasis--an alternative hypothesis. Cancer. 2005 Apr 15; 103(8):1537-9.
PMID:
15739196
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Contractor R, Samudio IJ,
Estrov Z
, Harris D, McCubrey JA, Safe SH,
Andreeff M
,
Konopleva M
. A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia. Cancer Res. 2005 Apr 01; 65(7):2890-8.
PMID:
15805291
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Guikema JE, Fenton JA, de Boer C, Kleiverda K, Brink AA, Raap AK,
Estrov Z
, Schuuring E, Kluin PM. Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination. Genes Chromosomes Cancer. 2005 Feb; 42(2):164-9.
PMID:
15543623
.
Citations:
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Robinson S,
Estrov Z
,
Champlin R
,
Shpall E
, K?rbling M. Umbilical cord blood-derived cells for tissue repair. Cytotherapy. 2005; 7(3):258-61.
PMID:
16081352
.
Citations:
10
Fields:
Cel
Cell Biology
The
Therapeutics
Translation:
Humans
Animals
Cells
Zhang S, Wang D,
Estrov Z
, Raj S, Willerson JT, Yeh ET. Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo. Circulation. 2004 Dec 21; 110(25):3803-7.
PMID:
15596566
.
Citations:
54
Fields:
Car
Cardiology
Vas
Vascular Diseases
Translation:
Humans
Animals
Cells
Konopleva M
, Tsao T,
Estrov Z
, Lee RM, Wang RY, Jackson CE, McQueen T, Monaco G, Munsell M,
Belmont J
,
Kantarjian H
, Sporn MB,
Andreeff M
. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia. Cancer Res. 2004 Nov 01; 64(21):7927-35.
PMID:
15520199
.
Citations:
55
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Faderl S,
Gandhi V
, O'Brien S, Bonate P,
Cortes J
, Estey E, Beran M,
Wierda W
,
Garcia-Manero G
,
Ferrajoli A
,
Estrov Z
, Giles FJ, Du M, Kwari M, Keating M, Plunkett W,
Kantarjian H
. Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias. Blood. 2005 Feb 01; 105(3):940-7.
PMID:
15486072
.
Citations:
57
Fields:
Hem
Hematology
Translation:
Humans
CT
Clinical Trials
Verstovsek S
,
Estrov Z
. Arsenic derivatives as therapeutic agents for hematologic malignancies. Leuk Res. 2004 Sep; 28(9):901-3.
PMID:
15234564
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Bueso-Ramos CE
,
Ferrajoli A
,
Medeiros LJ
, Keating MJ,
Estrov Z
. Aberrant morphology, proliferation, and apoptosis of B-cell chronic lymphocytic leukemia cells. Hematology. 2004 Aug; 9(4):279-86.
PMID:
15621735
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Humans
Cells
Hennessy B,
Estrov Z
, K?rbling M. Circulating stem cells and tissue repair. Panminerva Med. 2004 Mar; 46(1):1-11.
PMID:
15238877
.
Citations:
4
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Bueso-Ramos CE
, Rocha FC, Shishodia S,
Medeiros LJ
,
Kantarjian HM
, Vadhan-Raj S,
Estrov Z
, Smith TL, Nguyen MH, Aggarwal BB. Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia. Hum Pathol. 2004 Feb; 35(2):246-53.
PMID:
14991544
.
Citations:
20
Fields:
Pat
Pathology
Translation:
Humans
Zhao S,
Konopleva M
, Cabreira-Hansen M, Xie Z,
Hu W
, Milella M,
Estrov Z
,
Mills GB
,
Andreeff M
. Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias. Leukemia. 2004 Feb; 18(2):267-75.
PMID:
14628071
.
Citations:
39
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Faderl S,
Estrov Z
. Hematopoietic recovery following induction therapy of acute leukemias: prognostic implications and a new look at the definition of remission. Leuk Lymphoma. 2004 Jan; 45(1):67-71.
PMID:
15061199
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Bharti AC, Shishodia S, Reuben JM,
Weber D
, Alexanian R, Raj-Vadhan S,
Estrov Z
, Talpaz M, Aggarwal BB. Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis. Blood. 2004 Apr 15; 103(8):3175-84.
PMID:
15070700
.
Citations:
115
Fields:
Hem
Hematology
Translation:
Humans
Cells
Thompson MP, Aggarwal BB, Shishodia S,
Estrov Z
, Kurzrock R. Autocrine lymphotoxin production in Epstein-Barr virus-immortalized B cells: induction via NF-kappaB activation mediated by EBV-derived latent membrane protein 1. Leukemia. 2003 Nov; 17(11):2196-201.
PMID:
14523478
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Yeh ET, Zhang S, Wu HD, Willerson JT,
Estrov Z
, K?rbling M. Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation. 2003 Oct 28; 108(17):2070-3.
PMID:
14568894
.
Citations:
116
Fields:
Car
Cardiology
Vas
Vascular Diseases
Translation:
Humans
Animals
Cells
Laurent E, Mitchell DL,
Estrov Z
, Lowery M, Tucker SL, Talpaz M, Kurzrock R. Impact of p210(Bcr-Abl) on ultraviolet C wavelength-induced DNA damage and repair. Clin Cancer Res. 2003 Sep 01; 9(10 Pt 1):3722-30.
PMID:
14506164
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Estrov Z
, K?rbling M. Adult stem cells for tissue repair - a new therapeutic concept? N Engl J Med. 2003 Aug 07; 349(6):570-82.
PMID:
12904523
.
Citations:
196
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Estrov Z
,
Champlin R
, K?rbling M. Adult stem cells and tissue repair. Bone Marrow Transplant. 2003 Aug; 32 Suppl 1:S23-4.
PMID:
12931235
.
Citations:
19
Fields:
Tra
Transplantation
Translation:
Humans
Animals
Cells
Grunberger T, Demin P, Rounova O, Sharfe N, Cimpean L, Dadi H, Freywald A,
Estrov Z
, Roifman CM. Inhibition of acute lymphoblastic and myeloid leukemias by a novel kinase inhibitor. Blood. 2003 Dec 01; 102(12):4153-8.
PMID:
12881315
.
Citations:
3
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Faderl S,
Estrov Z
. Commentary: effect of flavonoids on normal and leukemic cells. Leuk Res. 2003 Jun; 27(6):471-3.
PMID:
12648504
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Amin HM
, Jilani I, Estey EH, Keating MJ, Dey AL, Manshouri T,
Kantarjian HM
,
Estrov Z
,
Cortes JE
, Thomas DA, Giles FJ, Albitar M. Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome. Blood. 2003 Sep 01; 102(5):1866-8.
PMID:
12730116
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Estrov Z
, Shishodia S, Faderl S, Harris D, Van Q,
Kantarjian HM
, Talpaz M, Aggarwal BB. Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. Blood. 2003 Aug 01; 102(3):987-95.
PMID:
12689943
.
Citations:
82
Fields:
Hem
Hematology
Translation:
Humans
Cells
Faderl S, Harris D, Van Q,
Kantarjian HM
, Talpaz M,
Estrov Z
. Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces antiapoptotic and proapoptotic signals in acute myeloid leukemia. Blood. 2003 Jul 15; 102(2):630-7.
PMID:
12663443
.
Citations:
17
Fields:
Hem
Hematology
Translation:
Humans
Cells
Faderl S, Lotan R,
Kantarjian HM
, Harris D, Van Q,
Estrov Z
. N-(4-Hydroxylphenyl)retinamide (fenretinide, 4-HPR), a retinoid compound with antileukemic and proapoptotic activity in acute lymphoblastic leukemia (ALL). Leuk Res. 2003 Mar; 27(3):259-66.
PMID:
12537979
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ravandi F, Talpaz M,
Estrov Z
. Modulation of cellular signaling pathways: prospects for targeted therapy in hematological malignancies. Clin Cancer Res. 2003 Feb; 9(2):535-50.
PMID:
12576416
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Alvarado Y
,
Cortes J
,
Verstovsek S
, Thomas D, Faderl S,
Estrov Z
,
Kantarjian H
, Giles FJ. Pilot study of pegylated interferon-alpha 2b in patients with essential thrombocythemia. Cancer Chemother Pharmacol. 2003 Jan; 51(1):81-6.
PMID:
12497210
.
Citations:
10
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Ferrajoli A
, Keating MJ, Manshouri T, Giles FJ, Dey A,
Estrov Z
, Koller CA, Kurzrock R, Thomas DA, Faderl S, Lerner S, O'Brien S, Albitar M. The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia. Blood. 2002 Aug 15; 100(4):1215-9.
PMID:
12149200
.
Citations:
57
Fields:
Hem
Hematology
Translation:
Humans
Cells
Brouard M, Barrandon Y. Male cells in female recipients of hematopoietic-cell transplants. N Engl J Med. 2002 Jul 18; 347(3):218-20; author reply 218-20.
PMID:
12124415
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Cheng K, Kurzrock R, Qiu X,
Estrov Z
, Ku S, Dulski KM, Wang JY, Talpaz M. Reduced focal adhesion kinase and paxillin phosphorylation in BCR-ABL-transfected cells. Cancer. 2002 Jul 15; 95(2):440-50.
PMID:
12124845
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Ravandi F,
Cortes J
,
Estrov Z
, Thomas D, Giles FJ,
Huh YO
, Pierce S, O'Brien S, Faderl S,
Kantarjian HM
. CD56 expression predicts occurrence of CNS disease in acute lymphoblastic leukemia. Leuk Res. 2002 Jul; 26(7):643-9.
PMID:
12008081
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Lin CW, Manshouri T, Jilani I, Neuberg D, Patel K,
Kantarjian H
,
Andreeff M
,
Estrov Z
, Beran M, Keating M, Estey E, Albitar M. Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome. Leuk Res. 2002 Jun; 26(6):551-9.
PMID:
12007503
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Milella M,
Estrov Z
,
Kornblau SM
,
Carter BZ
,
Konopleva M
, Tari A, Schober WD, Harris D, Leysath CE, Lopez-Berestein G, Huang Z,
Andreeff M
. Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia. Blood. 2002 May 01; 99(9):3461-4.
PMID:
11964319
.
Citations:
31
Fields:
Hem
Hematology
Translation:
Humans
Cells
Katz RL
, Khanna A, Ruifrok AC,
Rondon G
, Albitar M,
Champlin RE
,
Estrov Z
, K?rbling M. Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells. N Engl J Med. 2002 Mar 07; 346(10):738-46.
PMID:
11882729
.
Citations:
168
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Hester J. RE: Therapeutic plasma exchange: a paired comparison of Fresenius AS104 vs. COBE Spectra. J Clin Apher. 2002; 17(1):49.
PMID:
11948708
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Cells
Konopleva M
, Tsao T,
Ruvolo P
, Stiouf I,
Estrov Z
, Leysath CE, Zhao S, Harris D, Chang S, Jackson CE, Munsell M, Suh N, Gribble G, Honda T, May WS, Sporn MB,
Andreeff M
. Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia. Blood. 2002 Jan 01; 99(1):326-35.
PMID:
11756188
.
Citations:
74
Fields:
Hem
Hematology
Translation:
Humans
Cells
Faderl S,
Estrov Z
. Shift of immunoglobulin phenotypes in B-cell precursor cell lines. Leuk Res. 2002 Jan; 26(1):11-2.
PMID:
11734298
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Faderl S,
Estrov Z
,
Kantarjian HM
, Harris D, Van Q, Fokt I, Przewloka T, Godlewski C, Woynarowski JM,
Priebe W
. WP744, a novel anthracycline with enhanced proapoptotic and antileukemic activity. Anticancer Res. 2001 Nov-Dec; 21(6A):3777-84.
PMID:
11911247
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Milella M,
Kornblau SM
,
Estrov Z
, Carter BZ, Lapillonne H, Harris D,
Konopleva M
, Zhao S, Estey E,
Andreeff M
. Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia. J Clin Invest. 2001 Sep; 108(6):851-9.
PMID:
11560954
; PMCID:
PMC200930
.
Citations:
105
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Ravandi F,
Kantarjian HM
, Talpaz M, O'Brien S, Faderl S, Giles FJ, Thomas D,
Cortes J
,
Andreeff M
,
Estrov Z
, Rios MB, Albitar M. Expression of apoptosis proteins in chronic myelogenous leukemia: associations and significance. Cancer. 2001 Jun 01; 91(11):1964-72.
PMID:
11391574
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Ferrajoli A
, Manshouri T,
Estrov Z
, Keating MJ, O'Brien S,
Lerner S
, Beran M,
Kantarjian HM
, Freireich EJ, Albitar M. High levels of vascular endothelial growth factor receptor-2 correlate with shortened survival in chronic lymphocytic leukemia. Clin Cancer Res. 2001 Apr; 7(4):795-9.
PMID:
11309324
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Faderl S,
Estrov Z
. The clinical significance of caspase regulation in acute leukemia. Leuk Lymphoma. 2001 Feb; 40(5-6):471-81.
PMID:
11426520
.
Citations:
2
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Wang Y, Liu J,
Wu Y
, Luo W,
Lin SH
, Lin H, Hawk N, Sun T, Guo JQ,
Estrov Z
, Talpaz M,
Champlin R
, Arlinghaus RB. Expression of a truncated first exon BCR sequence in chronic myelogenous leukemia cells blocks cell growth and induces cell death. Cancer Res. 2001 Jan 01; 61(1):138-44.
PMID:
11196151
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Sarriera JE, Albitar M,
Estrov Z
, Gidel C, Aboul-Nasr R, Manshouri T,
Kornblau S
, Chang KS,
Kantarjian H
, Estey E. Comparison of outcome in acute myelogenous leukemia patients with translocation (8;21) found by standard cytogenetic analysis and patients with AML1/ETO fusion transcript found only by PCR testing. Leukemia. 2001 Jan; 15(1):57-61.
PMID:
11243400
.
Citations:
7
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Stock W,
Estrov Z
. Studies of minimal residual disease in acute lymphocytic leukemia. Hematol Oncol Clin North Am. 2000 Dec; 14(6):1289-305, viii-ix.
PMID:
11147224
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Faderl S,
Kantarjian HM
, Talpaz M,
Estrov Z
. Clinical significance of minimal residual disease in leukemia. Int J Oncol. 2000 Dec; 17(6):1277-87.
PMID:
11078816
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Faderl S,
Kantarjian HM
, Estey E, Manshouri T, Chan CY, Rahman Elsaied A,
Kornblau SM
,
Cortes J
, Thomas DA, Pierce S, Keating MJ,
Estrov Z
, Albitar M. The prognostic significance of p16(INK4a)/p14(ARF) locus deletion and MDM-2 protein expression in adult acute myelogenous leukemia. Cancer. 2000 Nov 01; 89(9):1976-82.
PMID:
11064355
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
Aguayo A,
Kantarjian H
, Manshouri T, Gidel C, Estey E, Thomas D, Koller C,
Estrov Z
, O'Brien S, Keating M, Freireich E, Albitar M. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood. 2000 Sep 15; 96(6):2240-5.
PMID:
10979972
.
Citations:
144
Fields:
Hem
Hematology
Translation:
Humans
Konkol B, Schulz A, Posern G, Lin H, Adermann K, Eulitz M,
Estrov Z
, Talpaz M, Arlinghaus RB, Feller SM, Kardinal C. Cell-penetrating SH3 domain blocker peptides inhibit proliferation of primary blast cells from CML patients. FASEB J. 2000 Aug; 14(11):1529-38.
PMID:
10928987
.
Citations:
12
Fields:
Bio
Biology
Phy
Physiology
Translation:
Humans
Animals
Cells
Konopleva M
, Tari AM,
Estrov Z
, Harris D, Xie Z, Zhao S,
Andreeff M
, L?pez-Berestein G. Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins. Blood. 2000 Jun 15; 95(12):3929-38.
PMID:
10845930
.
Citations:
13
Fields:
Hem
Hematology
Translation:
Humans
Cells
Mavligit GM,
Estrov Z
. CA 125: a clinically useful tumor marker in the management of colorectal carcinoma metastatic to the liver in patients with normal carcinoembryonic antigen. Am J Clin Oncol. 2000 Apr; 23(2):213-5.
PMID:
10776987
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Kornblau SM
, Vu HT, Ruvolo P,
Estrov Z
, O'Brien S,
Cortes J
,
Kantarjian H
,
Andreeff M
, May WS. BAX and PKCalpha modulate the prognostic impact of BCL2 expression in acute myelogenous leukemia. Clin Cancer Res. 2000 Apr; 6(4):1401-9.
PMID:
10778970
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ueno NT
,
Bartholomeusz C
, Herrmann JL,
Estrov Z
, Shao R,
Andreeff M
, Price J, Paul RW, Anklesaria P,
Yu D
, Hung MC. E1A-mediated paclitaxel sensitization in HER-2/neu-overexpressing ovarian cancer SKOV3.ip1 through apoptosis involving the caspase-3 pathway. Clin Cancer Res. 2000 Jan; 6(1):250-9.
PMID:
10656456
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Faderl S,
Kantarjian HM
, Thomas DA,
Cortes J
, Giles F, Pierce S, Albitar M,
Estrov Z
. Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia. Leuk Lymphoma. 2000 Jan; 36(3-4):263-73.
PMID:
10674898
.
Citations:
30
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Aguayo A, Estey E,
Kantarjian H
, Mansouri T, Gidel C, Keating M, Giles F,
Estrov Z
, Barlogie B, Albitar M. Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia. Blood. 1999 Dec 01; 94(11):3717-21.
PMID:
10572084
.
Citations:
45
Fields:
Hem
Hematology
Translation:
Humans
Ravandi F,
Estrov Z
, Kurzrock R, Breitmeyer JB, Maschek BJ, Talpaz M. A phase I study of recombinant interferon-beta in patients with advanced malignant disease. Clin Cancer Res. 1999 Dec; 5(12):3990-8.
PMID:
10632330
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Faderl S,
Thall PF
,
Kantarjian HM
, Talpaz M, Harris D, Van Q, Beran M,
Kornblau SM
, Pierce S,
Estrov Z
. Caspase 2 and caspase 3 as predictors of complete remission and survival in adults with acute lymphoblastic leukemia. Clin Cancer Res. 1999 Dec; 5(12):4041-7.
PMID:
10632337
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Moravcov? J, N?dvorn?kov? S, Luk?sov? M, Klamov? H. Polymerase chain reaction analyses should be used as a basis for clinical decision making in patients with chronic myelogenous leukemia. Blood. 1999 Nov 15; 94(10):3609-11.
PMID:
10610116
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Faderl S, Kurzrock R,
Estrov Z
. Minimal residual disease in hematologic disorders. Arch Pathol Lab Med. 1999 Nov; 123(11):1030-4.
PMID:
10539902
.
Citations:
1
Fields:
Pat
Pathology
Translation:
Humans
Andreeff M
, Jiang S, Zhang X,
Konopleva M
,
Estrov Z
, Snell VE, Xie Z,
Okcu MF
, Sanchez-Williams G, Dong J, Estey EH,
Champlin RC
,
Kornblau SM
, Reed JC, Zhao S. Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid. Leukemia. 1999 Nov; 13(11):1881-92.
PMID:
10557066
.
Citations:
36
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Estrov Z
, Manna SK, Harris D, Van Q, Estey EH,
Kantarjian HM
, Talpaz M, Aggarwal BB. Phenylarsine oxide blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, and induces apoptosis of acute myelogenous leukemia cells. Blood. 1999 Oct 15; 94(8):2844-53.
PMID:
10515888
.
Citations:
21
Fields:
Hem
Hematology
Translation:
Humans
Cells
Faderl S,
Estrov Z
,
Kantarjian HM
, Thomas D,
Cortes J
, Manshouri T, Chan CC, Hays KJ, Pierce S, Albitar M. The incidence of chromosome 9p21 abnormalities and deletions of tumor suppressor genes p15(INK4b)/p16(INK4a)/p14(ARF) in patients with acute lymphoblastic leukemia. Cytokines Cell Mol Ther. 1999 Sep; 5(3):159-63.
PMID:
10641574
.
Citations:
4
Fields:
All
Allergy and Immunology
Mol
Molecular Biology
The
Therapeutics
Translation:
Humans
Cells
Lion T. Monitoring of residual disease in chronic myelogenous leukemia by quantitative polymerase chain reaction and clinical decision making. Blood. 1999 Aug 15; 94(4):1486-8.
PMID:
10484639
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Faderl S, Talpaz M,
Estrov Z
,
Kantarjian HM
. Chronic myelogenous leukemia: biology and therapy. Ann Intern Med. 1999 Aug 03; 131(3):207-19.
PMID:
10428738
.
Citations:
70
Fields:
Int
Internal Medicine
Translation:
Humans
Cells
Faderl S, Talpaz M,
Estrov Z
, O'Brien S, Kurzrock R,
Kantarjian HM
. The biology of chronic myeloid leukemia. N Engl J Med. 1999 Jul 15; 341(3):164-72.
PMID:
10403855
.
Citations:
281
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Faderl S,
Kantarjian HM
, Manshouri T, Chan CY, Pierce S, Hays KJ,
Cortes J
, Thomas D,
Estrov Z
, Albitar M. The prognostic significance of p16INK4a/p14ARF and p15INK4b deletions in adult acute lymphoblastic leukemia. Clin Cancer Res. 1999 Jul; 5(7):1855-61.
PMID:
10430092
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kornblau SM
,
Thall PF
,
Estrov Z
, Walterscheid M, Patel S, Theriault A, Keating MJ,
Kantarjian H
, Estey E,
Andreeff M
. The prognostic impact of BCL2 protein expression in acute myelogenous leukemia varies with cytogenetics. Clin Cancer Res. 1999 Jul; 5(7):1758-66.
PMID:
10430080
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Beaupre DM, Talpaz M, Marini FC, Cristiano RJ, Roth JA,
Estrov Z
, Albitar M, Freedman MH, Kurzrock R. Autocrine interleukin-1beta production in leukemia: evidence for the involvement of mutated RAS. Cancer Res. 1999 Jun 15; 59(12):2971-80.
PMID:
10383163
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Mavligit GM,
Estrov Z
, Ayala A. Carcinoma of the stomach metastatic to the liver that progressed after hepatic arterial infusion of cisplatin plus 5-floxuridine, and then dramatically regressed after chemoembolization based on positive chromogranin staining. Am J Clin Oncol. 1999 Jun; 22(3):320-2.
PMID:
10362346
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Faderl S, Talpaz M,
Kantarjian HM
,
Estrov Z
. Should polymerase chain reaction analysis to detect minimal residual disease in patients with chronic myelogenous leukemia be used in clinical decision making? Blood. 1999 May 01; 93(9):2755-9.
PMID:
10216068
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Estrov Z
, Freedman MH. Detection of residual disease in acute lymphoblastic leukemia of childhood. Leuk Lymphoma. 1999 Mar; 33(1-2):47-52.
PMID:
10194120
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Konopleva M
, Mikhail A,
Estrov Z
, Zhao S, Harris D, Sanchez-Williams G,
Kornblau SM
, Dong J, Kliche KO, Jiang S, Snodgrass HR, Estey EH,
Andreeff M
. Expression and function of leptin receptor isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and anti-apoptotic activities. Blood. 1999 Mar 01; 93(5):1668-76.
PMID:
10029596
.
Citations:
39
Fields:
Hem
Hematology
Translation:
Humans
Cells
Faderl S,
Estrov Z
. Detection of residual disease in childhood acute lymphoblastic leukemia. N Engl J Med. 1999 Jan 14; 340(2):152-3; author reply 153-4.
PMID:
9917220
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Konopleva M
, Zhao S, Xie Z, Segall H, Younes A, Claxton DF,
Estrov Z
,
Kornblau SM
,
Andreeff M
. Apoptosis. Molecules and mechanisms. Adv Exp Med Biol. 1999; 457:217-36.
PMID:
10500797
.
Citations:
35
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Animals
Albitar M, Manshouri T,
Kantarjian H
, Keating M,
Estrov Z
, Faber J, Freireich EJ, Pierce S, Estey E. Correlation between lower c-mpl protein expression and favorable cytogenetic groups in acute myeloid leukemia. Leuk Res. 1999 Jan; 23(1):63-9.
PMID:
9933137
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Lee BN,
Duvic M
, Tang CK,
Bueso-Ramos C
,
Estrov Z
, Reuben JM. Dysregulated synthesis of intracellular type 1 and type 2 cytokines by T cells of patients with cutaneous T-cell lymphoma. Clin Diagn Lab Immunol. 1999 Jan; 6(1):79-84.
PMID:
9874668
; PMCID:
PMC95664
.
Citations:
18
Fields:
All
Allergy and Immunology
Cli
Clinical Laboratory Techniques
Translation:
Humans
Cells
Estrov Z
,
Thall PF
, Talpaz M, Estey EH,
Kantarjian HM
,
Andreeff M
, Harris D, Van Q, Walterscheid M,
Kornblau SM
. Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia. Blood. 1998 Nov 01; 92(9):3090-7.
PMID:
9787143
.
Citations:
43
Fields:
Hem
Hematology
Translation:
Humans
Cells
Konopleva M
,
Estrov Z
, Zhao S,
Andreeff M
, Mehta K. Ligation of cell surface CD38 protein with agonistic monoclonal antibody induces a cell growth signal in myeloid leukemia cells. J Immunol. 1998 Nov 01; 161(9):4702-8.
PMID:
9794400
.
Citations:
8
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Wright-Browne V, Schnee AM, Jenkins MA,
Thall PF
, Aggarwal BB, Talpaz M,
Estrov Z
. Serum cytokine levels in infectious mononucleosis at diagnosis and convalescence. Leuk Lymphoma. 1998 Aug; 30(5-6):583-9.
PMID:
9711920
.
Citations:
5
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Beran M, Cao X,
Estrov Z
, Jeha S, Jin G, O'Brien S, Talpaz M, Arlinghaus RB, Lydon NB,
Kantarjian H
. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148). Clin Cancer Res. 1998 Jul; 4(7):1661-72.
PMID:
9676840
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ferrajoli A
, Talpaz M, Kurzrock R, Harris D, Van Q, Estey EH,
Estrov Z
. Thrombopoietin stimulates myelodysplastic syndrome granulocyte-macrophage and erythroid progenitor proliferation. Leuk Lymphoma. 1998 Jul; 30(3-4):279-92.
PMID:
9713960
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Faderl S,
Estrov Z
. The clinical significance of detection of residual disease in childhood ALL. Crit Rev Oncol Hematol. 1998 Jun; 28(1):31-55.
PMID:
9715769
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Faderl S,
Estrov Z
. Residual disease in acute lymphoblastic leukemia of childhood: methods of detection and clinical relevance. Cytokines Cell Mol Ther. 1998 Jun; 4(2):73-85.
PMID:
9681246
.
Citations:
Fields:
All
Allergy and Immunology
Mol
Molecular Biology
The
Therapeutics
Translation:
Humans
Faderl S,
Kantarjian HM
, Talpaz M,
Estrov Z
. Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia. Blood. 1998 Jun 01; 91(11):3995-4019.
PMID:
9596644
.
Citations:
52
Fields:
Hem
Hematology
Translation:
Humans
Kurzrock R,
Estrov Z
,
Kantarjian H
, Talpaz M. Conversion of interferon-induced, long-term cytogenetic remissions in chronic myelogenous leukemia to polymerase chain reaction negativity. J Clin Oncol. 1998 Apr; 16(4):1526-31.
PMID:
9552062
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Estrov Z
, Talpaz M, Ku S, Harris D, Van Q, Beran M,
Hirsch-Ginsberg C
, Huh Y, Yee G, Kurzrock R. Z-138: a new mature B-cell acute lymphoblastic leukemia cell line from a patient with transformed chronic lymphocytic leukemia. Leuk Res. 1998 Apr; 22(4):341-53.
PMID:
9669839
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Liu J, Hadjokas N, Mosley B,
Estrov Z
, Spence MJ, Vestal RE. Oncostatin M-specific receptor expression and function in regulating cell proliferation of normal and malignant mammary epithelial cells. Cytokine. 1998 Apr; 10(4):295-302.
PMID:
9617575
.
Citations:
22
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Dhingra K,
Sahin A
, Emami K, Hortobagyi GN,
Estrov Z
. Expression of leukemia inhibitory factor and its receptor in breast cancer: a potential autocrine and paracrine growth regulatory mechanism. Breast Cancer Res Treat. 1998 Mar; 48(2):165-74.
PMID:
9596488
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Kurzrock R,
Estrov Z
, Ku S, Leonard M, Talpaz M. Interleukin-1 increases expression of the LYT-10 (NFkappaB2) proto-oncogene/transcription factor in renal cell carcinoma lines. J Lab Clin Med. 1998 Mar; 131(3):261-8.
PMID:
9523851
.
Citations:
1
Fields:
Cli
Clinical Laboratory Techniques
Med
Medicine (General)
Translation:
Humans
Cells
Kurzrock R, Talpaz M, Beran M, Harris D,
Estrov Z
. DNA in situ hybridization of individual colonies to determine lineage derivation in leukemia. Leukemia. 1998 Feb; 12(2):242-6.
PMID:
9519789
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Peleg S, Qiu H, Reddy S, Harris D, Van Q, Estey EH, Talpaz M,
Estrov Z
. 1,25-Dihydroxyvitamin D3 and its analogues inhibit acute myelogenous leukemia progenitor proliferation by suppressing interleukin-1beta production. J Clin Invest. 1997 Oct 01; 100(7):1716-24.
PMID:
9312169
; PMCID:
PMC508354
.
Citations:
4
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Wetzler M, Kurzrock R,
Estrov Z
, Barone S, Estey E, Talpaz M. Suppressed formation of bone marrow adherent layers derived from acute myeloid leukemia patients after in vitro exposure to interleukin-4. Leuk Res. 1997 Jun; 21(6):519-27.
PMID:
9279363
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Wright-Browne V,
McClain KL
, Talpaz M, Ordonez N,
Estrov Z
. Physiology and pathophysiology of dendritic cells. Hum Pathol. 1997 May; 28(5):563-79.
PMID:
9158705
.
Citations:
12
Fields:
Pat
Pathology
Translation:
Humans
Cells
Estrov Z
, Talpaz M. Role of interleukin-1 beta converting enzyme (ICE) in acute myelogenous leukemia cell proliferation and programmed cell death. Leuk Lymphoma. 1997 Feb; 24(5-6):379-91.
PMID:
9086432
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Roberts WM,
Estrov Z
, Ouspenskaia MV, Johnston DA,
McClain KL
, Zipf TF. Measurement of residual leukemia during remission in childhood acute lymphoblastic leukemia. N Engl J Med. 1997 Jan 30; 336(5):317-23.
PMID:
9011783
.
Citations:
14
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
McClain K
,
Estrov Z
, Raju U, Kelley PK, Aggarwal BB. Epstein-Barr Virus EBNA-2 gene expression enhances lymphotoxin production by B lymphocytes. Methods. 1997 Jan; 11(1):83-7.
PMID:
8990093
.
Citations:
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Lisovsky M,
Estrov Z
, Zhang X, Consoli U, Sanchez-Williams G, Snell V, Munker R, Goodacre A, Savchenko V,
Andreeff M
. Flt3 ligand stimulates proliferation and inhibits apoptosis of acute myeloid leukemia cells: regulation of Bcl-2 and Bax. Blood. 1996 Nov 15; 88(10):3987-97.
PMID:
8916965
.
Citations:
15
Fields:
Hem
Hematology
Translation:
Humans
Cells
Lapidot T, Grunberger T, Vormoor J,
Estrov Z
, Kollet O, Bunin N, Zaizov R, Williams DE, Freedman MH. Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice. Blood. 1996 Oct 01; 88(7):2655-64.
PMID:
8839860
.
Citations:
11
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Estrov Z
, Talpaz M, Ku S, Harris D, LaPushin R, Koller CA, Hirsh-Ginsberg C,
Huh Y
, Yee G, Kurzrock R. Molecular and biologic characterization of a newly established Philadelphia-positive acute lymphoblastic leukemia cell line (Z-33) with an autocrine response to GM-CSF. Leukemia. 1996 Sep; 10(9):1534-43.
PMID:
8751477
.
Citations:
4
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Kellokumpu-Lehtinen P, Talpaz M, Harris D, Van Q, Kurzrock R,
Estrov Z
. Leukemia-inhibitory factor stimulates breast, kidney and prostate cancer cell proliferation by paracrine and autocrine pathways. Int J Cancer. 1996 May 16; 66(4):515-9.
PMID:
8635867
.
Citations:
37
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Sarris AH, Talpaz M, Deisseroth AB,
Estrov Z
. Human recombinant interferon-inducible protein-10 inhibits the proliferation of normal and acute myelogenous leukemia progenitors. Leukemia. 1996 May; 10(5):757-65.
PMID:
8656668
.
Citations:
3
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Estrov Z
, Talpaz M. Role of interleukin-1 beta converting enzyme (ICE) in leukemia. Cytokines Mol Ther. 1996 Mar; 2(1):1-11.
PMID:
9384684
.
Citations:
Fields:
All
Allergy and Immunology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Estrov Z
, Talpaz M, Zipf TF,
Kantarjian HM
, Ku S, Ouspenskaia MV,
Hirsch-Ginsberg C
, Huh Y, Yee G, Kurzrock R. Role of granulocyte-macrophage colony-stimulating factor in Philadelphia (Ph1)-positive acute lymphoblastic leukemia: studies on two newly established Ph1-positive acute lymphoblastic leukemia cell lines (Z-119 and Z-181). J Cell Physiol. 1996 Mar; 166(3):618-30.
PMID:
8600166
.
Citations:
9
Fields:
Cel
Cell Biology
Phy
Physiology
Translation:
Humans
Cells
Roberts WM,
Estrov Z
, Kitchingman GR, Zipf TF. The clinical significance of residual disease in childhood acute lymphoblastic leukemia as detected by polymerase chain reaction amplification by antigen-receptor gene sequences. Leuk Lymphoma. 1996 Jan; 20(3-4):181-97.
PMID:
8624456
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Roberts WM,
Estrov Z
, Kitchingman GR, Zipf TF. Detection of minimal residual disease in all: biology, methods, and applications. Cancer Treat Res. 1996; 84:149-66.
PMID:
8724630
.
Citations:
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Estrov Z
, Black RA, Sleath PR, Harris D, Van Q, LaPushin R, Estey EH, Talpaz M. Effect of interleukin-1 beta converting enzyme inhibitor on acute myelogenous leukemia progenitor proliferation. Blood. 1995 Dec 15; 86(12):4594-602.
PMID:
8541550
.
Citations:
8
Fields:
Hem
Hematology
Translation:
Humans
Cells
Estrov Z
, Samal B, Lapushin R, Kellokumpu-Lehtinen P,
Sahin AA
, Kurzrock R, Talpaz M, Aggarwal BB. Leukemia inhibitory factor binds to human breast cancer cells and stimulates their proliferation. J Interferon Cytokine Res. 1995 Oct; 15(10):905-13.
PMID:
8564713
.
Citations:
17
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Kurzrock R, Wetzler M,
Estrov Z
, Talpaz M. Interleukin-1 and its inhibitors: a biologic and therapeutic model for the role of growth regulatory factors in leukemias. Cytokines Mol Ther. 1995 Sep; 1(3):177-84.
PMID:
9384674
.
Citations:
2
Fields:
All
Allergy and Immunology
Mol
Molecular Biology
Translation:
Humans
Animals
Estrov Z
, Talpaz M, Estey EH, Strassmann G. Role of suramin as an IL-1 inhibitor in suppression of acute myelogenous leukemia progenitor proliferation. Exp Hematol. 1995 Sep; 23(10):1080-7.
PMID:
7544738
.
Citations:
1
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Roberts WM,
Estrov Z
, Zipf TF. Detection of minimal residual disease in acute lymphoblastic leukemia. Blood. 1995 Aug 01; 86(3):1237-9.
PMID:
7620179
.
Citations:
Fields:
Hem
Hematology
Translation:
Humans
Estrov Z
, Kurzrock R, Talpaz M. Cytokines and their antagonists in myeloid disorders. Semin Hematol. 1995 Jul; 32(3):220-31.