BALRAJ SINGH

TitleAssociate Professor
InstitutionMD Anderson
DepartmentBreast Surgical Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Singh B, Sarli VN, Lucci A. Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine. Oncotarget. 2021 Mar 30; 12(7):626-637. PMID: 33868584.
      Citations:    Fields:    
    2. Singh B, Sarli VN, Kinne HE, Shamsnia A, Lucci A. Evaluation of 6-mercaptopurine in a cell culture model of adaptable triple-negative breast cancer with metastatic potential. Oncotarget. 2019 Jun 04; 10(38):3681-3693. PMID: 31217902.
      Citations: 1     Fields:    
    3. Singh B, Sarli VN, Washburn LJ, Raythatha MR, Lucci A. A usable model of "decathlon winner" cancer cells in triple-negative breast cancer: survival of resistant cancer cells in quiescence. Oncotarget. 2018 Feb 16; 9(13):11071-11082. PMID: 29541397.
      Citations: 3     Fields:    
    4. Singh B, Kinne HE, Milligan RD, Washburn LJ, Olsen M, Lucci A. Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge. PLoS One. 2016; 11(7):e0159072. PMID: 27390851.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    5. Singh B, Shamsnia A, Raythatha MR, Milligan RD, Cady AM, Madan S, Lucci A. Highly adaptable triple-negative breast cancer cells as a functional model for testing anticancer agents. PLoS One. 2014; 9(10):e109487. PMID: 25279830.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    6. Singh B, Tai K, Madan S, Raythatha MR, Cady AM, Braunlin M, Irving LR, Bajaj A, Lucci A. Selection of metastatic breast cancer cells based on adaptability of their metabolic state. PLoS One. 2012; 7(5):e36510. PMID: 22570721.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    7. Hall C, Krishnamurthy S, Lodhi A, Bhattacharyya A, Anderson A, Kuerer H, Bedrosian I, Singh B, Lucci A. Disseminated tumor cells predict survival after neoadjuvant therapy in primary breast cancer. Cancer. 2012 Jan 15; 118(2):342-8. PMID: 21717428.
      Citations: 13     Fields:    Translation:Humans
    8. Krishnamurthy S, Cristofanilli M, Singh B, Reuben J, Gao H, Cohen EN, Andreopoulou E, Hall CS, Lodhi A, Jackson S, Lucci A. Detection of minimal residual disease in blood and bone marrow in early stage breast cancer. Cancer. 2010 Jul 15; 116(14):3330-7. PMID: 20564098.
      Citations: 40     Fields:    Translation:HumansCells
    9. Singh B, Irving LR, Tai K, Lucci A. Overexpression of COX-2 in celecoxib-resistant breast cancer cell lines. J Surg Res. 2010 Oct; 163(2):235-43. PMID: 20691996.
      Citations: 7     Fields:    Translation:HumansCells
    10. Singh B, Cook KR, Vincent L, Hall CS, Martin C, Lucci A. Role of COX-2 in tumorospheres derived from a breast cancer cell line. J Surg Res. 2011 Jun 01; 168(1):e39-49. PMID: 20462604.
      Citations: 19     Fields:    Translation:HumansCells
    11. Singh B, Cook KR, Martin C, Huang EH, Mosalpuria K, Krishnamurthy S, Cristofanilli M, Lucci A. Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer. Clin Exp Metastasis. 2010 Apr; 27(4):233-40. PMID: 20229045.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    12. Zhang D, LaFortune TA, Krishnamurthy S, Esteva FJ, Cristofanilli M, Liu P, Lucci A, Singh B, Hung MC, Hortobagyi GN, Ueno NT. Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer. Clin Cancer Res. 2009 Nov 01; 15(21):6639-48. PMID: 19825949.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    13. Huang EH, Singh B, Cristofanilli M, Gelovani J, Wei C, Vincent L, Cook KR, Lucci A. A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer. J Surg Res. 2009 Aug; 155(2):231-6. PMID: 19482312.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    14. Lucci A, Krishnamurthy S, Singh B, Bedrosian I, Meric-Bernstam F, Reuben J, Broglio K, Mosalpuria K, Lodhi A, Vincent L, Cristofanilli M. Cyclooxygenase-2 expression in primary breast cancers predicts dissemination of cancer cells to the bone marrow. Breast Cancer Res Treat. 2009 Sep; 117(1):61-8. PMID: 18663571.
      Citations: 17     Fields:    Translation:Humans
    15. Singh B, Cook KR, Vincent L, Hall CS, Berry JA, Multani AS, Lucci A. Cyclooxygenase-2 induces genomic instability, BCL2 expression, doxorubicin resistance, and altered cancer-initiating cell phenotype in MCF7 breast cancer cells. J Surg Res. 2008 Jun 15; 147(2):240-6. PMID: 18498876.
      Citations: 25     Fields:    Translation:HumansCells
    16. Lang JE, Mosalpuria K, Cristofanilli M, Krishnamurthy S, Reuben J, Singh B, Bedrosian I, Meric-Bernstam F, Lucci A. HER2 status predicts the presence of circulating tumor cells in patients with operable breast cancer. Breast Cancer Res Treat. 2009 Feb; 113(3):501-7. PMID: 18327638.
      Citations: 30     Fields:    Translation:HumansCellsCTClinical Trials
    17. Lang JE, Hall CS, Singh B, Lucci A. Significance of micrometastasis in bone marrow and blood of operable breast cancer patients: research tool or clinical application? Expert Rev Anticancer Ther. 2007 Oct; 7(10):1463-72. PMID: 17944570.
      Citations: 7     Fields:    Translation:HumansCells
    18. Singh B, Vincent L, Berry JA, Multani AS, Lucci A. Cyclooxygenase-2 expression induces genomic instability in MCF10A breast epithelial cells. J Surg Res. 2007 Jun 15; 140(2):220-6. PMID: 17418864.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    19. Singh B, Berry JA, Shoher A, Ayers GD, Wei C, Lucci A. COX-2 involvement in breast cancer metastasis to bone. Oncogene. 2007 May 31; 26(26):3789-96. PMID: 17213821.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    20. Singh B, Berry JA, Vincent LE, Lucci A. Involvement of IL-8 in COX-2-mediated bone metastases from breast cancer. J Surg Res. 2006 Jul; 134(1):44-51. PMID: 16678856.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    21. Singh B, Berry JA, Shoher A, Lucci A. COX-2 induces IL-11 production in human breast cancer cells. J Surg Res. 2006 Apr; 131(2):267-75. PMID: 16457848.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    22. Singh B, Berry JA, Shoher A, Ramakrishnan V, Lucci A. COX-2 overexpression increases motility and invasion of breast cancer cells. Int J Oncol. 2005 May; 26(5):1393-9. PMID: 15809733.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    23. Singh B, Lucci A. Role of cyclooxygenase-2 in breast cancer. J Surg Res. 2002 Nov; 108(1):173-9. PMID: 12472107.
      Citations: 18     Fields:    Translation:HumansAnimals
    24. Pham CD, Vuyyuru VB, Yang Y, Bai W, Singh B. Evidence for an important role of serine 16 and its phosphorylation in the stabilization of c-Mos. Oncogene. 1999 Jul 29; 18(30):4287-94. PMID: 10439036.
      Citations: 5     Fields:    Translation:AnimalsCells
    25. Liu H, Vuyyuru VB, Pham CD, Yang Y, Singh B. Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association. Oncogene. 1999 Jun 10; 18(23):3461-70. PMID: 10376524.
      Citations: 4     Fields:    Translation:AnimalsCells
    26. Ling YH, Yang Y, Tornos C, Singh B, Perez-Soler R. Paclitaxel-induced apoptosis is associated with expression and activation of c-Mos gene product in human ovarian carcinoma SKOV3 cells. Cancer Res. 1998 Aug 15; 58(16):3633-40. PMID: 9721872.
      Citations: 10     Fields:    Translation:HumansCells
    27. Yang Y, Pham CD, Vuyyuru VB, Liu H, Arlinghaus RB, Singh B. Evidence of a functional interaction between serine 3 and serine 25 Mos phosphorylation sites. A dominant inhibitory role of serine 25 phosphorylation on Mos protein kinase. J Biol Chem. 1998 Jun 26; 273(26):15946-53. PMID: 9632642.
      Citations: 2     Fields:    Translation:AnimalsCells
    28. Yang Y, Pham CD, Arlinghaus RB, Khillan JS, Singh B. Elevated level of cyclin D1 in mos-transformed cells. Int J Oncol. 1998 May; 12(5):1199-202. PMID: 9538150.
      Citations:    Fields:    Translation:AnimalsCells
    29. Tsui L, Ramagli L, Gao C, Pham C, Pandita T, Arlinghaus R, Singh B. The biological effects of antisense mos expression in fibroblasts. Int J Oncol. 1997 Dec; 11(6):1171-8. PMID: 21528318.
      Citations:    Fields:    
    30. Singh B, Arlinghaus RB. Mos and the cell cycle. Prog Cell Cycle Res. 1997; 3:251-9. PMID: 9552420.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    31. Gao C, Arlinghaus RB, Singh B. Further characterization of the c-mos transcript and its cell cycle specific expression in NIH3T3 cells. Oncogene. 1996 Apr 04; 12(7):1571-6. PMID: 8622874.
      Citations: 1     Fields:    Translation:AnimalsCells
    32. Yang Y, Herrmann CH, Arlinghaus RB, Singh B. Inhibition of v-Mos kinase activity by protein kinase A. Mol Cell Biol. 1996 Mar; 16(3):800-9. PMID: 8622681.
      Citations: 3     Fields:    Translation:AnimalsCells
    33. Lengye E, Singh B, Gum R, Nerlov C, Sabichi A, Birrer M, Boyd D. Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene. Oncogene. 1995 Dec 21; 11(12):2639-48. PMID: 8545121.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    34. Pham CD, Arlinghaus RB, Zheng CF, Guan KL, Singh B. Characterization of MEK1 phosphorylation by the v-Mos protein. Oncogene. 1995 Apr 20; 10(8):1683-8. PMID: 7731726.
      Citations: 9     Fields:    Translation:AnimalsCells
    35. Bai W, Arlinghaus RB, Singh B. Association of v-Mos with soluble vimentin in vitro and in transformed cells. Oncogene. 1993 Aug; 8(8):2207-12. PMID: 8336943.
      Citations: 1     Fields:    Translation:AnimalsCells
    36. Bai W, Singh B, Yang Y, Arlinghaus RB. Evidence for interaction between v-Mos and a p34cdc2 isoform, p35cdk. Oncogene. 1992 Sep; 7(9):1757-63. PMID: 1323818.
      Citations: 1     Fields:    Translation:AnimalsCells
    37. Bai W, Singh B, Yang Y, Ramagli LS, Nash M, Herzog NK, Arlinghaus RB. The physical interactions between p37env-mos and tubulin structures. Oncogene. 1992 Mar; 7(3):493-500. PMID: 1532247.
      Citations: 4     Fields:    Translation:AnimalsCells
    38. Singh B, Stocking C, Walker R, Yang YD, Ostertag W, Arlinghaus RB. v-mos proteins encoded by myeloproliferative sarcoma virus and its ts159 mutant. J Virol. 1992 Feb; 66(2):1267-72. PMID: 1309903.
      Citations: 1     Fields:    Translation:AnimalsCells
    39. Singh B, Arlinghaus RB. The mos proto-oncogene product: its role in oocyte maturation, metaphase arrest, and neoplastic transformation. Mol Carcinog. 1992; 6(3):182-9. PMID: 1332729.
      Citations: 3     Fields:    Translation:AnimalsCells
    40. Bai WL, Singh B, Karshin WL, Shonk RA, Arlinghaus RB. Phosphorylation of v-mos Ser 47 by the mitotic form of p34cdc2. Oncogene. 1991 Oct; 6(10):1715-23. PMID: 1833715.
      Citations: 4     Fields:    Translation:AnimalsCells
    41. Zhao X, Singh B, Arlinghaus RB. Inhibition of c-mos protein kinase blocks mouse zygotes at the pronuclei stage. Oncogene. 1991 Aug; 6(8):1423-6. PMID: 1832216.
      Citations: 1     Fields:    Translation:AnimalsCells
    42. Zhao X, Singh B, Batten BE. The role of c-mos proto-oncoprotein in mammalian meiotic maturation. Oncogene. 1991 Jan; 6(1):43-9. PMID: 1825139.
      Citations: 1     Fields:    Translation:AnimalsCells
    43. Zhao X, Batten B, Singh B, Arlinghaus RB. Requirement of the c-mos protein kinase for murine meiotic maturation. Oncogene. 1990 Nov; 5(11):1727-30. PMID: 2176285.
      Citations: 3     Fields:    Translation:AnimalsCells
    44. Singh B, al-Bagdadi F, Liu JX, Arlinghaus RB. Use of antipeptide antibodies to probe the catalytic activity of p37v-mos. Virology. 1990 Oct; 178(2):535-42. PMID: 2171192.
      Citations: 3     Fields:    Translation:AnimalsCells
    45. al-Bagdadi F, Singh B, Arlinghaus RB. Evidence for involvement of the protein kinase C pathway in the activation of p37v-mos protein kinase. Oncogene. 1990 Aug; 5(8):1251-7. PMID: 2168030.
      Citations: 3     Fields:    Translation:Cells
    46. Roy LM, Singh B, Gautier J, Arlinghaus RB, Nordeen SK, Maller JL. The cyclin B2 component of MPF is a substrate for the c-mos(xe) proto-oncogene product. Cell. 1990 Jun 01; 61(5):825-31. PMID: 2140529.
      Citations: 26     Fields:    Translation:AnimalsCells
    47. Hamelin R, Honore N, Sergiescu D, Singh B, Gerfaux J, Arlinghaus RB. Reversion of thermosensitive splicing defect of Moloney murine sarcoma virus ts110 by oversplicing of viral RNA. J Virol. 1990 Mar; 64(3):1378-82. PMID: 2154617.
      Citations:    Fields:    Translation:AnimalsCells
    48. Liu JX, Singh B, Wlodek D, Arlinghaus RB. Cell cycle-mediated structural and functional alteration of P85gag-mos protein kinase activity. Oncogene. 1990 Feb; 5(2):171-8. PMID: 2138725.
      Citations: 4     Fields:    Translation:AnimalsCells
    49. Singh B, Arlinghaus RB. Vimentin phosphorylation by p37mos protein kinase in vitro and generation of a 50-kDa cleavage product in v-mos-transformed cells. Virology. 1989 Nov; 173(1):144-56. PMID: 2554568.
      Citations: 10     Fields:    Translation:AnimalsCells
    50. Herzog NK, Singh B, Elder J, Lipkin I, Trauger RJ, Millette CF, Goldman DS, Wolfes H, Cooper GM, Arlinghaus RB. Identification of the protein product of the c-mos proto-oncogene in mouse testes. Oncogene. 1988 Aug; 3(2):225-9. PMID: 2970613.
      Citations: 10     Fields:    Translation:AnimalsCells
    51. Singh B, Wittenberg C, Hannink M, Reed SI, Donoghue DJ, Arlinghaus RB. The histidine-221 to tyrosine substitution in v-mos abolishes its biological function and its protein kinase activity. Virology. 1988 May; 164(1):114-20. PMID: 2966489.
      Citations: 8     Fields:    Translation:AnimalsCells
    52. Singh B, Goldman R, Hutton L, Herzog NK, Arlinghaus RB. The P55 protein affected by v-mos expression is vimentin. J Virol. 1987 Nov; 61(11):3625-9. PMID: 2822968.
      Citations: 3     Fields:    Translation:AnimalsCells
    53. Singh B, Hannink M, Donoghue DJ, Arlinghaus RB. p37mos-associated serine/threonine protein kinase activity correlates with the cellular transformation function of v-mos. J Virol. 1986 Dec; 60(3):1148-52. PMID: 3023666.
      Citations: 13     Fields:    Translation:Cells
    54. Escobedo J, Singh B, Dina D, Arlinghaus RB. Temperature-dependent cytocidal effects of Moloney murine sarcoma virus. Virus Res. 1986 Oct; 6(1):75-84. PMID: 3026112.
      Citations: 3     Fields:    Translation:AnimalsCells
    55. Singh B, Wittenberg C, Reed SI, Arlinghaus RB. Moloney murine sarcoma virus encoded p37mos expressed in yeast has protein kinase activity. Virology. 1986 Jul 30; 152(2):502-6. PMID: 3014729.
      Citations: 8     Fields:    Translation:AnimalsCells
    56. Singh B, Sparrow JT, Hedge AM, Arlinghaus RB. Expression of the v-mos gene alters a Mr 55,000 protein during acute infection by Moloney murine sarcoma virus. Proc Natl Acad Sci U S A. 1986 Jun; 83(11):3629-33. PMID: 3012522.
      Citations: 2     Fields:    Translation:AnimalsCells
    57. Gallick GE, Sparrow JT, Singh B, Maxwell SA, Stanker LH, Arlinghaus RB. Recognition of mos-related proteins with an antiserum to a peptide of the v-mos gene product. J Gen Virol. 1985 May; 66 ( Pt 5):945-55. PMID: 2987403.
      Citations: 11     Fields:    Translation:AnimalsCells
    58. Biswas M, Singh B, Rai YP, Datta A. Turnover of inducible N-acetylglucosamine catabolic enzymes in Candida albicans. Indian J Exp Biol. 1982 Nov; 20(11):829-34. PMID: 6762985.
      Citations: 1     Fields:    Translation:Animals
    59. Singh B, Thornton GB, Roy J, Talib S, De BP, Banerjee AK. Frequent intragenic transcription termination within the N gene of vesicular stomatitis virus. Virology. 1982 Oct 30; 122(2):239-50. PMID: 6293173.
      Citations: 1     Fields:    Translation:AnimalsCells
    60. Singh B, Guptaroy B, Hasan G, Datta A. Inhibitory effect of glucose and adenosine 3',5'-monophosphate on the synthesis of inducible N-acetylglucosamine catabolic enzymes in yeast. Biochim Biophys Acta. 1980 Oct 15; 632(3):345-53. PMID: 6251914.
      Citations: 4     Fields:    Translation:Animals
    61. Singh B, Biswas M, Datta A. Inducible N-acetyglucosamine-binding protein in yeasts. J Bacteriol. 1980 Oct; 144(1):1-6. PMID: 6998941.
      Citations:    Fields:    Translation:AnimalsCells
    62. Rai YP, Singh B, Elango N, Datta A. Purification and some properties of inducible N-acetylglucosamine kinase from Candida albicans. Biochim Biophys Acta. 1980 Aug 07; 614(2):350-6. PMID: 6250622.
      Citations:    Fields:    Translation:Animals
    63. Singh B, Datta A. Regulation of N-acetylglucosamine uptake in yeast. Biochim Biophys Acta. 1979 Oct 19; 557(1):248-58. PMID: 398716.
      Citations: 13     Fields:    Translation:Animals
    64. Biswas M, Singh B, Datta A. Induction of N-acetylmannosamine catabolic pathway in yeast. Biochim Biophys Acta. 1979 Jul 18; 585(4):535-42. PMID: 223651.
      Citations: 6     Fields:    Translation:Animals
    65. Singh B, Datta A. Regulation of glucosamine-6-phosphate deaminase synthesis in yeast. Biochim Biophys Acta. 1979 Feb 19; 583(1):28-35. PMID: 369615.
      Citations: 1     Fields:    Translation:Animals
    66. Singh B, Datta A. Induction of N-acetylglucosamine-catabolic pathway in spheroplasts of Candida albicans. Biochem J. 1979 Feb 15; 178(2):427-31. PMID: 220965.
      Citations: 7     Fields:    Translation:AnimalsCells
    67. Singh BR, Datta A. Glucose repression of the inducible catabolic pathway for N-acetylglucosamine in yeast. Biochem Biophys Res Commun. 1978 Sep 14; 84(1):58-64. PMID: 215141.
      Citations: 5     Fields:    Translation:Animals
    68. Important role of FTO in the survival of rare panresistant triple-negative inflammatory breast cancer cells facing a severe metabolic challenge. PLoS One. 11.
    69. p37(mos) encoded by the HT-1 strain of Moloney murine sarcoma virus has an associated protein kinase activity. Oncogene. 3:79-85.
    70. Essential role of c-mos in eggs. International Journal of Gynecological Cancer. 7:314-317.
    71. Somatic cell expression of the mos proto-oncogene is cell cycle regulated. International Journal of Oncology. 2:493-502.
    72. Erratum. Journal of Surgical Research. 162:169.
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