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PENG HUANG

TitleProfessor
InstitutionMD Anderson
DepartmentTranslational Molecular Pathology
Address2130 W Holcombe Blvd
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W. Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy. Cell Metab. 2018 May 01; 27(5):977-987.e4. PMID: 29628419.
      View in: PubMed
    2. Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, DePinho RA, Huang P, Xu RH, Chiao PJ. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017 Feb 24; 8:14437. PMID: 28232723.
      View in: PubMed
    3. Fiskus W, Coothankandaswamy V, Chen J, Ma H, Ha K, Saenz DT, Krieger SS, Mill CP, Sun B, Huang P, Mumm JS, Melnick AM, Bhalla KN. SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents. Cancer Res. 2016 Sep 15; 76(18):5467-78. PMID: 27503926.
      View in: PubMed
    4. Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio AL, Gomes Dias SM, Calin GA. Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2. Mol Cell. 2016 Feb 18; 61(4):520-34. PMID: 26853146.
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    5. Huang D, Huang P, Lin D, Zeng G. Long-distance continuous-variable quantum key distribution by controlling excess noise. Sci Rep. 2016; 6:19201. PMID: 26758727.
      View in: PubMed
    6. Huang P, Xiao A, Tong X, Lin S, Zhang B. Targeted Mutagenesis in Zebrafish by TALENs. Methods Mol Biol. 2016; 1338:191-206. PMID: 26443223.
      View in: PubMed
    7. Zhu D, Liu P, Lu W, Wang H, Luo B, Hu Y, Huang P, Wen S. Relayed Regioselective Alkynylation/Olefination of Unsymmetrical Cyclic Diaryliodonium Species Catalyzed by Cu and Pd: Affording Fluorescent Cytotoxic Benzoxazoles. Chemistry. 2015 Dec 21; 21(52):18915-20. PMID: 26516085.
      View in: PubMed
    8. Wu Y, Wu F, Zhu D, Luo B, Wang H, Hu Y, Wen S, Huang P. Pd catalyzed insertion of alkynes into cyclic diaryliodoniums: a direct access to multi-substituted phenanthrenes. Org Biomol Chem. 2015 Nov 7; 13(41):10386-91. PMID: 26324765.
      View in: PubMed
    9. Yuan S, Lu Y, Yang J, Chen G, Kim S, Feng L, Ogasawara M, Hammoudi N, Lu W, Zhang H, Liu J, Colman H, Lee JS, Li XN, Xu RH, Huang P, Wang F. Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism. Stem Cell Res Ther. 2015; 6:198. PMID: 26472041.
      View in: PubMed
    10. Wang C, Huang D, Huang P, Lin D, Peng J, Zeng G. 25?MHz clock continuous-variable quantum key distribution system over 50?km fiber channel. Sci Rep. 2015; 5:14607. PMID: 26419413.
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    11. He Q, Kiesewetter DO, Qu Y, Fu X, Fan J, Huang P, Liu Y, Zhu G, Liu Y, Qian Z, Chen X. NIR-Responsive On-Demand Release of CO from Metal Carbonyl-Caged Graphene Oxide Nanomedicine. Adv Mater. 2015 Nov; 27(42):6741-6. PMID: 26401893.
      View in: PubMed
    12. Wang P, Zhu CF, Ma MZ, Chen G, Song M, Zeng ZL, Lu WH, Yang J, Wen S, Chiao PJ, Hu Y, Huang P. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget. 2015 Aug 28; 6(25):21148-58. PMID: 26020803.
      View in: PubMed
    13. Huang P, Gao Y, Lin J, Hu H, Liao HS, Yan X, Tang Y, Jin A, Song J, Niu G, Zhang G, Horkay F, Chen X. Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics. ACS Nano. 2015 Oct 27; 9(10):9517-27. PMID: 26301492.
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    14. Men K, Dai JR, Li MH, Chen XY, Zhang K, Tian Y, Huang P, Xu YJ. A Method to Improve Electron Density Measurement of Cone-Beam CT Using Dual Energy Technique. Biomed Res Int. 2015; 2015:858907. PMID: 26346510.
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    15. Ma MZ, Chen G, Wang P, Lu WH, Zhu CF, Song M, Yang J, Wen S, Xu RH, Hu Y, Huang P. Xc- inhibitor sulfasalazine sensitizes colorectal cancer to cisplatin by a GSH-dependent mechanism. Cancer Lett. 2015 Nov 1; 368(1):88-96. PMID: 26254540.
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    16. Kandasamy K, Chuah JK, Su R, Huang P, Eng KG, Xiong S, Li Y, Chia CS, Loo LH, Zink D. Prediction of drug-induced nephrotoxicity and injury mechanisms with human induced pluripotent stem cell-derived cells and machine learning methods. Sci Rep. 2015; 5:12337. PMID: 26212763.
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    17. Huang P, Tan J, Ma W, Zheng H, Lu Y, Wang N, Peng Z, Yu R. Long-Term Effectiveness of Antiretroviral Therapy in China: An Observational Cohort Study from 2003-2014. Int J Environ Res Public Health. 2015 Aug; 12(8):8762-72. PMID: 26213959.
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    18. Pan J, Sheng Y, Zhang J, Wei J, Huang P, Zhang X, Feng B. The photosensitivity of carbon quantum dots/CuAlO2 films composites. Nanotechnology. 2015 Jul 31; 26(30):305201. PMID: 26150398.
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    19. Song J, Huang P, Duan H, Chen X. Plasmonic Vesicles of Amphiphilic Nanocrystals: Optically Active Multifunctional Platform for Cancer Diagnosis and Therapy. Acc Chem Res. 2015 Sep 15; 48(9):2506-15. PMID: 26134093.
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    20. Chang X, Xi YB, Cui LB, Wang HN, Sun JB, Zhu YQ, Huang P, Collin G, Liu K, Xi M, Qi S, Tan QR, Miao DM, Yin H. Distinct inter-hemispheric dysconnectivity in schizophrenia patients with and without auditory verbal hallucinations. Sci Rep. 2015; 5:11218. PMID: 26053998.
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    21. Shi H, Yang S, Liu Y, Huang P, Lin N, Sun X, Yu R, Zhang Y, Qin Y, Wang L. Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease. PLoS One. 2015; 10(6):e0128646. PMID: 26035828.
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    22. Huang P, Tan J, Ma W, Zheng H, Lu Y, Wang N, Peng Z, Yu R. Outcomes of antiretroviral treatment in HIV-infected adults: a dynamic and observational cohort study in Shenzhen, China, 2003-2014. BMJ Open. 2015; 5(5):e007508. PMID: 26002691.
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    23. Raman SP, Schroeder JL, Huang P, Chen Y, Coquia SF, Kawamoto S, Fishman EK. Preliminary data using computed tomography texture analysis for the classification of hypervascular liver lesions: generation of a predictive model on the basis of quantitative spatial frequency measurements--a work in progress. J Comput Assist Tomogr. 2015 May-Jun; 39(3):383-95. PMID: 25700222.
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    24. Huang P, Zhang Y, Lu X, Xu Y, Wang J, Zhang Y, Yu R, Su J. Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection. PLoS One. 2015; 10(4):e0123513. PMID: 25874709.
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    25. Wang P, Sun YC, Lu WH, Huang P, Hu Y. Selective killing of K-ras-transformed pancreatic cancer cells by targeting NAD(P)H oxidase. Chin J Cancer. 2015 Apr; 34(4):166-76. PMID: 25963558.
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    26. Kinoshita R, Watanabe M, Huang P, Li SA, Sakaguchi M, Kumon H, Futami J. The cysteine-rich core domain of REIC/Dkk-3 is critical for its effect on monocyte differentiation and tumor regression. Oncol Rep. 2015 Jun; 33(6):2908-14. PMID: 25823913.
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    27. Wang P, Song M, Zeng ZL, Zhu CF, Lu WH, Yang J, Ma MZ, Huang AM, Hu Y, Huang P. Identification of NDUFAF1 in mediating K-Ras induced mitochondrial dysfunction by a proteomic screening approach. Oncotarget. 2015 Feb 28; 6(6):3947-62. PMID: 25714130.
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    28. Stonestrom AJ, Hsu SC, Jahn KS, Huang P, Keller CA, Giardine BM, Kadauke S, Campbell AE, Evans P, Hardison RC, Blobel GA. Functions of BET proteins in erythroid gene expression. Blood. 2015 Apr 30; 125(18):2825-34. PMID: 25696920.
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    29. Li W, Rong P, Yang K, Huang P, Sun K, Chen X. Semimetal nanomaterials of antimony as highly efficient agent for photoacoustic imaging and photothermal therapy. Biomaterials. 2015 Mar; 45:18-26. PMID: 25662491.
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    30. Wang S, Teng Z, Huang P, Liu D, Liu Y, Tian Y, Sun J, Li Y, Ju H, Chen X, Lu G. Reversibly extracellular pH controlled cellular uptake and photothermal therapy by PEGylated mixed-charge gold nanostars. Small. 2015 Apr 17; 11(15):1801-10. PMID: 25565411.
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    31. Huang P, Chang S, Jiang X, Su J, Dong C, Liu X, Yuan Z, Zhang Z, Liao H. RNA interference targeting CD147 inhibits the proliferation, invasiveness, and metastatic activity of thyroid carcinoma cells by down-regulating glycolysis. Int J Clin Exp Pathol. 2015; 8(1):309-18. PMID: 25755717.
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    32. Huang P, Chen C, Liu-Chen LY. Detection of mu opioid receptor (MOPR) and its glycosylation in rat and mouse brains by western blot with anti-?C, an affinity-purified polyclonal anti-MOPR antibody. Methods Mol Biol. 2015; 1230:141-54. PMID: 25293322.
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    33. Vendetti FP, Topper M, Huang P, Dobromilskaya I, Easwaran H, Wrangle J, Baylin SB, Poirier JT, Rudin CM. Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer. Oncotarget. 2015 Jan 1; 6(1):56-70. PMID: 25474141.
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    34. Xu Y, Fu LR, Jia M, Dai G, Wang Q, Huang P, Zheng H, Peng Z, Wang L, Yu R, Wang N. HIV prevalence and associated factors among foreign brides from Burma in Yunnan Province, China. PLoS One. 2014; 9(12):e115599. PMID: 25536087.
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    35. Wang Y, Lang L, Huang P, Wang Z, Jacobson O, Kiesewetter DO, Ali IU, Teng G, Niu G, Chen X. In vivo albumin labeling and lymphatic imaging. Proc Natl Acad Sci U S A. 2015 Jan 6; 112(1):208-13. PMID: 25535368.
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    36. Ju HQ, Gocho T, Aguilar M, Wu M, Zhuang ZN, Fu J, Yanaga K, Huang P, Chiao PJ. Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation. Mol Cancer Ther. 2015 Mar; 14(3):788-98. PMID: 25527634.
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    37. Yan X, Niu G, Lin J, Jin AJ, Hu H, Tang Y, Zhang Y, Wu A, Lu J, Zhang S, Huang P, Shen B, Chen X. Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide. Biomaterials. 2015 Feb; 42:94-102. PMID: 25542797.
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    38. Nie L, Huang P, Li W, Yan X, Jin A, Wang Z, Tang Y, Wang S, Zhang X, Niu G, Chen X. Early-stage imaging of nanocarrier-enhanced chemotherapy response in living subjects by scalable photoacoustic microscopy. ACS Nano. 2014 Dec 23; 8(12):12141-50. PMID: 25406986.
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    39. Liu Z, Zhu D, Luo B, Zhang N, Liu Q, Hu Y, Pi R, Huang P, Wen S. Mild Cu(I)-catalyzed cascade reaction of cyclic diaryliodoniums, sodium azide, and alkynes: efficient synthesis of triazolophenanthridines. Org Lett. 2014 Nov 7; 16(21):5600-3. PMID: 25338129.
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    40. Hu H, Huang P, Weiss OJ, Yan X, Yue X, Zhang MG, Tang Y, Nie L, Ma Y, Niu G, Wu K, Chen X. PET and NIR optical imaging using self-illuminating (64)Cu-doped chelator-free gold nanoclusters. Biomaterials. 2014 Dec; 35(37):9868-76. PMID: 25224367.
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    41. Li YJ, Huang P, Jiang CL, Jia de X, Du XX, Zhou JH, Han Y, Sui H, Wei XL, Liu L, Yuan HH, Zhang TT, Zhang WJ, Xie R, Lang XH, Wang LY, Liu T, Bai YX, Tian Y. Sonodynamically induced anti-tumor effect of 5-aminolevulinic acid on pancreatic cancer cells. Ultrasound Med Biol. 2014 Nov; 40(11):2671-9. PMID: 25220273.
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    42. Pelicano H, Zhang W, Liu J, Hammoudi N, Dai J, Xu RH, Pusztai L, Huang P. Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential. Breast Cancer Res. 2014; 16(5):434. PMID: 25209360.
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    43. Huang P, Rong P, Jin A, Yan X, Zhang MG, Lin J, Hu H, Wang Z, Yue X, Li W, Niu G, Zeng W, Wang W, Zhou K, Chen X. Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy. Adv Mater. 2014 Oct 8; 26(37):6401-8. PMID: 25123089.
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    44. Xing Q, Huang P, Yang J, Sun JQ, Gong Z, Dong X, Guo DC, Chen SM, Yang YH, Wang Y, Yang MH, Yi M, Ding YM, Liu ML, Zhang WP, Tang C. Visualizing an ultra-weak protein-protein interaction in phosphorylation signaling. Angew Chem Int Ed Engl. 2014 Oct 20; 53(43):11501-5. PMID: 25131700.
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    45. Chang Z, Ju H, Ling J, Zhuang Z, Li Z, Wang H, Fleming JB, Freeman JW, Yu D, Huang P, Chiao PJ. Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis. PLoS One. 2014; 9(7):e101452. PMID: 25029561.
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    46. Yin Y, Huang P, Han Z, Wei G, Zhou C, Wen J, Su B, Wang X, Wang Y. Collagen nanofibers facilitated presynaptic maturation in differentiated neurons from spinal-cord-derived neural stem cells through MAPK/ERK1/2-Synapsin I signaling pathway. Biomacromolecules. 2014 Jul 14; 15(7):2449-60. PMID: 24955924.
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    47. Huang P, Rong P, Lin J, Li W, Yan X, Zhang MG, Nie L, Niu G, Lu J, Wang W, Chen X. Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics. J Am Chem Soc. 2014 Jun 11; 136(23):8307-13. PMID: 24842342.
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    48. Gagnon JA, Valen E, Thyme SB, Huang P, Akhmetova L, Ahkmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PLoS One. 2014; 9(5):e98186. PMID: 24873830.
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    49. Chen DL, Wang ZQ, Zeng ZL, Wu WJ, Zhang DS, Luo HY, Wang F, Qiu MZ, Wang DS, Ren C, Wang FH, Chiao LJ, Pelicano H, Huang P, Li YH, Xu RH. Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression. Hepatology. 2014 Aug; 60(2):598-609. PMID: 24616020.
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    50. Li YJ, Zhou JH, Du XX, Jia de X, Wu CL, Huang P, Han Y, Sui H, Wei XL, Liu L, Yuan HH, Zhang TT, Zhang WJ, Xie R, Lang XH, Liu T, Jiang CL, Wang LY, Bai YX. Dihydroartemisinin accentuates the anti-tumor effects of photodynamic therapy via inactivation of NF-?B in Eca109 and Ec9706 esophageal cancer cells. Cell Physiol Biochem. 2014; 33(5):1527-36. PMID: 24854841.
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    51. Wang Z, Yue X, Wang Y, Qian C, Huang P, Lizak M, Niu G, Wang F, Rong P, Kiesewetter DO, Ma Y, Chen X. A symmetrical fluorous dendron-cyanine dye-conjugated bimodal nanoprobe for quantitative 19F MRI and NIR fluorescence bioimaging. Adv Healthc Mater. 2014 Aug; 3(8):1326-33. PMID: 24789108.
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    52. Luo Y, Gou X, Huang P, Mou C. The PCA3 test for guiding repeat biopsy of prostate cancer and its cut-off score: a systematic review and meta-analysis. Asian J Androl. 2014 May-Jun; 16(3):487-92. PMID: 24713827.
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    53. Han X, Dong X, Jiang WX, Huang P, Zhang WP, Tang C. [A method based on endogenous fluorescence determination for screening NAMPT inhibitors]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2014 May; 43(3):319-26. PMID: 24998656.
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    54. Zhu D, Wu Y, Wu B, Luo B, Ganesan A, Wu FH, Pi R, Huang P, Wen S. Three-component Pd/Cu-catalyzed cascade reactions of cyclic iodoniums, alkynes, and boronic acids: an approach to methylidenefluorenes. Org Lett. 2014 May 2; 16(9):2350-3. PMID: 24742135.
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    55. Duan M, Huang P, Yuan X, Chen H, Huang J, Zhang H. CMYB1 encoding a MYB transcriptional activator is involved in abiotic stress and circadian rhythm in rice. ScientificWorldJournal. 2014; 2014:178038. PMID: 24977183.
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    56. Fiskus W, Saba N, Shen M, Ghias M, Liu J, Gupta SD, Chauhan L, Rao R, Gunewardena S, Schorno K, Austin CP, Maddocks K, Byrd J, Melnick A, Huang P, Wiestner A, Bhalla KN. Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia. Cancer Res. 2014 May 1; 74(9):2520-32. PMID: 24599128; PMCID: PMC4172421.
    57. Kang P, Wan M, Huang P, Li C, Wang Z, Zhong X, Hu Z, Tai S, Cui Y. The Wnt antagonist sFRP1 as a favorable prognosticator in human biliary tract carcinoma. PLoS One. 2014; 9(3):e90308. PMID: 24594839.
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    58. Li Y, Fu L, Li JB, Qin Y, Zeng TT, Zhou J, Zeng ZL, Chen J, Cao TT, Ban X, Qian C, Cai Z, Xie D, Huang P, Guan XY. Increased expression of EIF5A2, via hypoxia or gene amplification, contributes to metastasis and angiogenesis of esophageal squamous cell carcinoma. Gastroenterology. 2014 Jun; 146(7):1701-13.e9. PMID: 24561231.
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    59. Huang P, Xiao A, Tong X, Zu Y, Wang Z, Zhang B. TALEN construction via "Unit Assembly" method and targeted genome modifications in zebrafish. Methods. 2014 Aug 15; 69(1):67-75. PMID: 24556555.
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    60. Cao D, Kishida S, Huang P, Mu P, Tsubota S, Mizuno M, Kadomatsu K. A new tumorsphere culture condition restores potentials of self-renewal and metastasis of primary neuroblastoma in a mouse neuroblastoma model. PLoS One. 2014; 9(1):e86813. PMID: 24466252.
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    61. Luo Y, Gou X, Huang P, Mou C. Prostate cancer antigen 3 test for prostate biopsy decision: a systematic review and meta analysis. Chin Med J (Engl). 2014; 127(9):1768-74. PMID: 24791889.
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    62. Zhao B, Zhang M, Han X, Zhang XY, Xing Q, Dong X, Shi QJ, Huang P, Lu YB, Wei EQ, Xia Q, Zhang WP, Tang C. Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism. PLoS One. 2013; 8(12):e85403. PMID: 24392007.
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    63. Watanabe M, Sakaguchi M, Kinoshita R, Kaku H, Ariyoshi Y, Ueki H, Tanimoto R, Ebara S, Ochiai K, Futami J, Li SA, Huang P, Nasu Y, Huh NH, Kumon H. A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector. Oncol Rep. 2014 Mar; 31(3):1089-95. PMID: 24398705.
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    64. Yamada H, Abe T, Li SA, Tago S, Huang P, Watanabe M, Ikeda S, Ogo N, Asai A, Takei K. N'-[4-(dipropylamino)benzylidene]-2-hydroxybenzohydrazide is a dynamin GTPase inhibitor that suppresses cancer cell migration and invasion by inhibiting actin polymerization. Biochem Biophys Res Commun. 2014 Jan 10; 443(2):511-7. PMID: 24316215.
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    65. Li M, Luo B, Liu Q, Hu Y, Ganesan A, Huang P, Wen S. Synthesis of N-acyl-N,O-acetals mediated by titanium ethoxide. Org Lett. 2014 Jan 3; 16(1):10-3. PMID: 24308842.
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    66. Zeng ZL, Luo HY, Yang J, Wu WJ, Chen DL, Huang P, Xu RH. Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer. Clin Cancer Res. 2014 Feb 15; 20(4):1042-52. PMID: 24277452.
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    67. Nie L, Wang S, Wang X, Rong P, Ma Y, Liu G, Huang P, Lu G, Chen X. In vivo volumetric photoacoustic molecular angiography and therapeutic monitoring with targeted plasmonic nanostars. Small. 2014 Apr 24; 10(8):1585-93, 1441. PMID: 24150920.
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    68. Liu PP, Liao J, Tang ZJ, Wu WJ, Yang J, Zeng ZL, Hu Y, Wang P, Ju HQ, Xu RH, Huang P. Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway. Cell Death Differ. 2014 Jan; 21(1):124-35. PMID: 24096870; PMCID: PMC3857620.
    69. Li J, Li B, Huang P, Shi HY, Huang RB, Zheng LS, Tao J. Four coordination polymers based on identical eight-connected heptanuclear clusters: spin canting, spin glass, antiferromagnetism, and gas adsorption. Inorg Chem. 2013 Oct 7; 52(19):11573-9. PMID: 24067134.
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    70. Liu L, Bai YX, Zhou JH, Sun XW, Sui H, Zhang WJ, Yuan HH, Xie R, Wei XL, Zhang TT, Huang P, Li YJ, Wang JX, Zhao S, Zhang QY. A polymorphism at the 3'-UTR region of the aromatase gene is associated with the efficacy of the aromatase inhibitor, anastrozole, in metastatic breast carcinoma. Int J Mol Sci. 2013; 14(9):18973-88. PMID: 24065098.
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    71. Li X, Lu W, Hu Y, Wen S, Qian C, Wu W, Huang P. Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate. Int J Oncol. 2013 Nov; 43(5):1710-8. PMID: 23982861.
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    72. Schweizer MT, Huang P, Kattan MW, Kibel AS, de Wit R, Sternberg CN, Epstein JI, Eisenberger MA. Adjuvant leuprolide with or without docetaxel in patients with high-risk prostate cancer after radical prostatectomy (TAX-3501): important lessons for future trials. Cancer. 2013 Oct 15; 119(20):3610-8. PMID: 23943299.
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    73. Zhu D, Chen M, Li M, Luo B, Zhao Y, Huang P, Xue F, Rapposelli S, Pi R, Wen S. Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity. Eur J Med Chem. 2013 Oct; 68:81-8. PMID: 23973819.
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    74. Li Z, Qiu Y, Personett D, Huang P, Edenfield B, Katz J, Babusis D, Tang Y, Shirely MA, Moghaddam MF, Copland JA, Tun HW. Pomalidomide shows significant therapeutic activity against CNS lymphoma with a major impact on the tumor microenvironment in murine models. PLoS One. 2013; 8(8):e71754. PMID: 23940785.
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    75. Huang P, Chiu YT, Chen C, Wang Y, Liu-Chen LY. A G protein-coupled receptor (GPCR) in red: live cell imaging of the kappa opioid receptor-tdTomato fusion protein (KOPR-tdT) in neuronal cells. J Pharmacol Toxicol Methods. 2013 Nov-Dec; 68(3):340-5. PMID: 23856011.
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    76. Xiao A, Wang Z, Hu Y, Wu Y, Luo Z, Yang Z, Zu Y, Li W, Huang P, Tong X, Zhu Z, Lin S, Zhang B. Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res. 2013 Aug; 41(14):e141. PMID: 23748566.
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    77. Lin J, Wang S, Huang P, Wang Z, Chen S, Niu G, Li W, He J, Cui D, Lu G, Chen X, Nie Z. Photosensitizer-loaded gold vesicles with strong plasmonic coupling effect for imaging-guided photothermal/photodynamic therapy. ACS Nano. 2013 Jun 25; 7(6):5320-9. PMID: 23721576.
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    78. Wang Z, Zhang X, Huang P, Zhao W, Liu D, Nie L, Yue X, Wang S, Ma Y, Kiesewetter D, Niu G, Chen X. Dual-factor triggered fluorogenic nanoprobe for ultrahigh contrast and subdiffraction fluorescence imaging. Biomaterials. 2013 Aug; 34(26):6194-201. PMID: 23721793.
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    79. Wang X, Huang P, Liu H, Li C, Shen G, Cui D. Metal ion-directed solution-phase tailoring: from large-area graphene oxide into nanoscale pieces. Nanoscale Res Lett. 2013; 8(1):226. PMID: 23672471.
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    80. Rudin CM, Brahmer JR, Juergens RA, Hann CL, Ettinger DS, Sebree R, Smith R, Aftab BT, Huang P, Liu JO. Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non-small-cell lung cancer. J Thorac Oncol. 2013 May; 8(5):619-23. PMID: 23546045.
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    81. Xiong F, Tentner AR, Huang P, Gelas A, Mosaliganti KR, Souhait L, Rannou N, Swinburne IA, Obholzer ND, Cowgill PD, Schier AF, Megason SG. Specified neural progenitors sort to form sharp domains after noisy Shh signaling. Cell. 2013 Apr 25; 153(3):550-61. PMID: 23622240.
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    179. Chen J, Watanabe M, Huang P, Sakaguchi M, Ochiai K, Nasu Y, Ouchida M, Huh NH, Shimizu K, Kashiwakura Y, Kaku H, Kumon H. REIC/Dkk-3 stable transfection reduces the malignant phenotype of mouse prostate cancer RM9 cells. Int J Mol Med. 2009 Dec; 24(6):789-94. PMID: 19885619.
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    183. Mague SD, Isiegas C, Huang P, Liu-Chen LY, Lerman C, Blendy JA. Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10847-52. PMID: 19528658.
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    187. Chen G, Izzo J, Demizu Y, Wang F, Guha S, Wu X, Hung MC, Ajani JA, Huang P. Different redox states in malignant and nonmalignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol. Antioxid Redox Signal. 2009 May; 11(5):1083-95. PMID: 19187006; PMCID: PMC2842128.
    188. Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP. Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Dev Cell. 2009 Apr; 16(4):600-6. PMID: 19386268.
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    189. Chen Z, Zhang H, Lu W, Huang P. Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. Biochim Biophys Acta. 2009 May; 1787(5):553-60. PMID: 19285479; PMCID: PMC2731236.
    190. Pelicano H, Lu W, Zhou Y, Zhang W, Chen Z, Hu Y, Huang P. Mitochondrial dysfunction and reactive oxygen species imbalance promote breast cancer cell motility through a CXCL14-mediated mechanism. Cancer Res. 2009 Mar 15; 69(6):2375-83. PMID: 19276362; PMCID: PMC2760349.
    191. Sun Y, Chen ZL, Yang XX, Huang P, Zhou XP, Du XX. Magnetic chitosan nanoparticles as a drug delivery system for targeting photodynamic therapy. Nanotechnology. 2009 Apr 1; 20(13):135102. PMID: 19420486.
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    192. Watanabe M, Kashiwakura Y, Huang P, Ochiai K, Futami J, Li SA, Takaoka M, Nasu Y, Sakaguchi M, Huh NH, Kumon H. Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression. Int J Oncol. 2009 Mar; 34(3):657-63. PMID: 19212670.
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    193. Lockrow J, Prakasam A, Huang P, Bimonte-Nelson H, Sambamurti K, Granholm AC. Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model. Exp Neurol. 2009 Apr; 216(2):278-89. PMID: 19135442.
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    194. Izzo JG, Wu X, Wu TT, Huang P, Lee JS, Liao Z, Lee JH, Bhutani MS, Hofstetter W, Maru D, Hung MC, Ajani JA. Therapy-induced expression of NF-kappaB portends poor prognosis in patients with localized esophageal cancer undergoing preoperative chemoradiation. Dis Esophagus. 2009; 22(2):127-32. PMID: 19021681.
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    196. Nawrocki ST, Carew JS, Maclean KH, Courage JF, Huang P, Houghton JA, Cleveland JL, Giles FJ, McConkey DJ. Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA. Blood. 2008 Oct 1; 112(7):2917-26. PMID: 18641367.
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    197. Huang P, Wang CY, Gou SM, Wu HS, Liu T, Xiong JX. Isolation and biological analysis of tumor stem cells from pancreatic adenocarcinoma. World J Gastroenterol. 2008 Jun 28; 14(24):3903-7. PMID: 18609717.
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    198. Trachootham D, Zhang H, Zhang W, Feng L, Du M, Zhou Y, Chen Z, Pelicano H, Plunkett W, Wierda WG, Keating MJ, Huang P. Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism. Blood. 2008 Sep 1; 112(5):1912-22. PMID: 18574029.
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    199. Hu W, Hofstetter W, Guo W, Li H, Pataer A, Peng HH, Guo ZS, Bartlett DL, Lin A, Swisher SG, Fang B. JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase. Cancer Gene Ther. 2008 Sep; 15(9):616-24. PMID: 18535619; PMCID: PMC2553758.
    200. Tsutsui M, Hasegawa H, Adachi K, Miyata M, Huang P, Ishiguro N, Hamaguchi M, Iwamoto T. Establishment of cells to monitor Microprocessor through fusion genes of microRNA and GFP. Biochem Biophys Res Commun. 2008 Aug 8; 372(4):856-61. PMID: 18533106.
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    201. Wei W, Wen L, Huang P, Zhang Z, Chen Y, Xiao A, Huang H, Zhu Z, Zhang B, Lin S. Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis. Cell Res. 2008 Jun; 18(6):677-85. PMID: 18504458.
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    202. Demizu Y, Sasaki R, Trachootham D, Pelicano H, Colacino JA, Liu J, Huang P. Alterations of cellular redox state during NNK-induced malignant transformation and resistance to radiation. Antioxid Redox Signal. 2008 May; 10(5):951-61. PMID: 18257743; PMCID: PMC2717788.
    203. Yen CJ, Izzo JG, Lee DF, Guha S, Wei Y, Wu TT, Chen CT, Kuo HP, Hsu JM, Sun HL, Chou CK, Buttar NS, Wang KK, Huang P, Ajani J, Hung MC. Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. Cancer Res. 2008 Apr 15; 68(8):2632-40. PMID: 18413730; PMCID: PMC2377413.
    204. Zhang H, Trachootham D, Lu W, Carew J, Giles FJ, Keating MJ, Arlinghaus RB, Huang P. Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism. Leukemia. 2008 Jun; 22(6):1191-9. PMID: 18385754.
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    205. Sasaki R, Suzuki Y, Yonezawa Y, Ota Y, Okamoto Y, Demizu Y, Huang P, Yoshida H, Sugimura K, Mizushina Y. DNA polymerase gamma inhibition by vitamin K3 induces mitochondria-mediated cytotoxicity in human cancer cells. Cancer Sci. 2008 May; 99(5):1040-8. PMID: 18312466.
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    206. Yuen HK, Huang P, Burik JK, Smith TG. Impact of participating in volunteer activities for residents living in long-term-care facilities. Am J Occup Ther. 2008 Jan-Feb; 62(1):71-6. PMID: 18254433.
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    207. Wen L, Wei W, Gu W, Huang P, Ren X, Zhang Z, Zhu Z, Lin S, Zhang B. Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Dev Biol. 2008 Feb 1; 314(1):84-92. PMID: 18164283.
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    209. Chen Z, Lu W, Garcia-Prieto C, Huang P. The Warburg effect and its cancer therapeutic implications. J Bioenerg Biomembr. 2007 Jun; 39(3):267-74. PMID: 17551814.
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    210. Alexandre J, Hu Y, Lu W, Pelicano H, Huang P. Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species. Cancer Res. 2007 Apr 15; 67(8):3512-7. PMID: 17440056.
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    211. Carew JS, Nawrocki ST, Kahue CN, Zhang H, Yang C, Chung L, Houghton JA, Huang P, Giles FJ, Cleveland JL. Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance. Blood. 2007 Jul 1; 110(1):313-22. PMID: 17363733; PMCID: PMC1896119.
    212. Niu J, Chang Z, Peng B, Xia Q, Lu W, Huang P, Tsao MS, Chiao PJ. Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. J Biol Chem. 2007 Mar 2; 282(9):6001-11. PMID: 17200110.
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    213. Pelicano H, Xu RH, Du M, Feng L, Sasaki R, Carew JS, Hu Y, Ramdas L, Hu L, Keating MJ, Zhang W, Plunkett W, Huang P. Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism. J Cell Biol. 2006 Dec 18; 175(6):913-23. PMID: 17158952.
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    216. Pelicano H, Martin DS, Xu RH, Huang P. Glycolysis inhibition for anticancer treatment. Oncogene. 2006 Aug 7; 25(34):4633-46. PMID: 16892078.
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    217. Achanta G, Modzelewska A, Feng L, Khan SR, Huang P. A boronic-chalcone derivative exhibits potent anticancer activity through inhibition of the proteasome. Mol Pharmacol. 2006 Jul; 70(1):426-33. PMID: 16636137.
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    218. Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M, Konopleva M. Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia. Cancer Res. 2006 Apr 1; 66(7):3737-46. PMID: 16585200.
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    221. Hu N, Li Z, Huang P, Tao C. Distribution and mobility of metals in agricultural soils near a copper smelter in South China. Environ Geochem Health. 2006 Feb-Apr; 28(1-2):19-26. PMID: 16528598.
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    225. Lu Z, Luo RZ, Peng H, Huang M, Nishmoto A, Hunt KK, Helin K, Liao WS, Yu Y. E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer. Oncogene. 2006 Jan 12; 25(2):230-9. PMID: 16158053.
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    226. Samudio I, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann W, Ying Y, Evans R, Contractor R, Andreeff M. A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis. Mol Pharmacol. 2006 Apr; 69(4):1182-93. PMID: 16410408.
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    229. Chen KJ, Chen LW, Liao JM, Chen CH, Ho YC, Ho YC, Cheng CL, Lin JJ, Huang PC, Lin TB. Effects of a calcineurin inhibitor, tacrolimus, on glutamate-dependent potentiation in pelvic-urethral reflex in anesthetized rats. Neuroscience. 2006; 138(1):69-76. PMID: 16359812.
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    231. Xu RH, Pelicano H, Zhang H, Giles FJ, Keating MJ, Huang P. Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells. Leukemia. 2005 Dec; 19(12):2153-8. PMID: 16193082.
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    232. Zhou C, Huang P, Liu J. The carboxyl-terminal of BRCA1 is required for subnuclear assembly of RAD51 after treatment with cisplatin but not ionizing radiation in human breast and ovarian cancer cells. Biochem Biophys Res Commun. 2005 Oct 28; 336(3):952-60. PMID: 16165098.
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    233. Wang Y, Hao LB, Zhou YG, Li JD, Wang JF, Tang PF, Huang P. [Clinical experience of treating infection after total hip arthroplasty]. Zhonghua Wai Ke Za Zhi. 2005 Oct 15; 43(20):1313-6. PMID: 16271242.
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    234. Hu Y, Rosen DG, Zhou Y, Feng L, Yang G, Liu J, Huang P. Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress. J Biol Chem. 2005 Nov 25; 280(47):39485-92. PMID: 16179351.
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    235. Achanta G, Sasaki R, Feng L, Carew JS, Lu W, Pelicano H, Keating MJ, Huang P. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. EMBO J. 2005 Oct 5; 24(19):3482-92. PMID: 16163384; PMCID: PMC1276176.
    236. Carew JS, Nawrocki ST, Krupnik YV, Dunner K, McConkey DJ, Keating MJ, Huang P. Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL. Blood. 2006 Jan 1; 107(1):222-31. PMID: 16144803.
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    237. Liu X, Guo Y, Li Y, Jiang Y, Chubb S, Azuma A, Huang P, Matsuda A, Hittelman W, Plunkett W. Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation. Cancer Res. 2005 Aug 1; 65(15):6874-81. PMID: 16061671.
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    238. Huang P, Stern MJ. FGF signaling in flies and worms: more and more relevant to vertebrate biology. Cytokine Growth Factor Rev. 2005 Apr; 16(2):151-8. PMID: 15863031.
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    239. Xu RH, Pelicano H, Zhou Y, Carew JS, Feng L, Bhalla KN, Keating MJ, Huang P. Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res. 2005 Jan 15; 65(2):613-21. PMID: 15695406.
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    240. Carew JS, Nawrocki ST, Xu RH, Dunner K, McConkey DJ, Wierda WG, Keating MJ, Huang P. Increased mitochondrial biogenesis in primary leukemia cells: the role of endogenous nitric oxide and impact on sensitivity to fludarabine. Leukemia. 2004 Dec; 18(12):1934-40. PMID: 15483672.
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    241. Choi W, Gerner EW, Ramdas L, Dupart J, Carew J, Proctor L, Huang P, Zhang W, Hamilton SR. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells. J Biol Chem. 2005 Feb 4; 280(5):3295-304. PMID: 15546879; PMCID: PMC3584635.
    242. Zhou NN, Zhu XF, Zhou JM, Li MZ, Zhang XS, Huang P, Jiang WQ. 2-Methoxyestradiol induces cell cycle arrest and apoptosis of nasopharyngeal carcinoma cells. Acta Pharmacol Sin. 2004 Nov; 25(11):1515-20. PMID: 15525476.
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    243. Achanta G, Huang P. Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents. Cancer Res. 2004 Sep 1; 64(17):6233-9. PMID: 15342409.
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    245. Huang P, Steplock D, Weinman EJ, Hall RA, Ding Z, Li J, Wang Y, Liu-Chen LY. kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins. J Biol Chem. 2004 Jun 11; 279(24):25002-9. PMID: 15070904.
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    246. Pelicano H, Carney D, Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist Updat. 2004 Apr; 7(2):97-110. PMID: 15158766.
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    247. Mone AP, Huang P, Pelicano H, Cheney CM, Green JM, Tso JY, Johnson AJ, Jefferson S, Lin TS, Byrd JC. Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells. Blood. 2004 Mar 1; 103(5):1846-54. PMID: 14630799.
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    248. Hileman EO, Liu J, Albitar M, Keating MJ, Huang P. Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity. Cancer Chemother Pharmacol. 2004 Mar; 53(3):209-19. PMID: 14610616.
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    249. Wen X, Wu QP, Ke S, Wallace S, Charnsangavej C, Huang P, Liang D, Chow D, Li C. Improved radiolabeling of PEGylated protein: PEGylated annexin V for noninvasive imaging of tumor apoptosis. Cancer Biother Radiopharm. 2003 Oct; 18(5):819-27. PMID: 14629830.
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    250. Carew JS, Zhou Y, Albitar M, Carew JD, Keating MJ, Huang P. Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications. Leukemia. 2003 Aug; 17(8):1437-47. PMID: 12886229.
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    251. Pelicano H, Feng L, Zhou Y, Carew JS, Hileman EO, Plunkett W, Keating MJ, Huang P. Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. J Biol Chem. 2003 Sep 26; 278(39):37832-9. PMID: 12853461.
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    252. Huang X, Huang P, Robinson MK, Stern MJ, Jin Y. UNC-71, a disintegrin and metalloprotease (ADAM) protein, regulates motor axon guidance and sex myoblast migration in C. elegans. Development. 2003 Jul; 130(14):3147-61. PMID: 12783787.
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    253. Zhou Y, Hileman EO, Plunkett W, Keating MJ, Huang P. Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents. Blood. 2003 May 15; 101(10):4098-104. PMID: 12531810.
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    254. Carew JS, Huang P. Mitochondrial defects in cancer. Mol Cancer. 2002 Dec 9; 1:9. PMID: 12513701; PMCID: PMC149412.
    255. Huang P, Visiers I, Weinstein H, Liu-Chen LY. The local environment at the cytoplasmic end of TM6 of the mu opioid receptor differs from those of rhodopsin and monoamine receptors: introduction of an ionic lock between the cytoplasmic ends of helices 3 and 6 by a L6.30(275)E mutation inactivates the mu opioid receptor and reduces the constitutive activity of its T6.34(279)K mutant. Biochemistry. 2002 Oct 8; 41(40):11972-80. PMID: 12356297.
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    256. Fu L, Pelicano H, Liu J, Huang P, Lee C. The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell. 2002 Oct 4; 111(1):41-50. PMID: 12372299.
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    257. Zhou Y, Achanta G, Pelicano H, Gandhi V, Plunkett W, Huang P. Action of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on DNA metabolism: incorporation, excision, and cellular response. Mol Pharmacol. 2002 Jan; 61(1):222-9. PMID: 11752224.
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    258. Achanta G, Pelicano H, Feng L, Plunkett W, Huang P. Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage. Cancer Res. 2001 Dec 15; 61(24):8723-9. PMID: 11751391.
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    259. Ballal K, Zhang W, Mukhopadyay T, Huang P. Suppression of mismatched mutation by p53: a mechanism for guarding genomic integrity. J Mol Med (Berl). 2002 Jan; 80(1):25-32. PMID: 11862321.
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    260. Azuma A, Huang P, Matsuda A, Plunkett W. Cellular pharmacokinetics and pharmacodynamics of the deoxycytidine analog 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC). Biochem Pharmacol. 2001 Jun 15; 61(12):1497-507. PMID: 11377379.
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    261. Azuma A, Huang P, Matsuda A, Plunkett W. 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest. Mol Pharmacol. 2001 Apr; 59(4):725-31. PMID: 11259616.
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    262. Jabbur JR, Huang P, Zhang W. Enhancement of the antiproliferative function of p53 by phosphorylation at serine 20: an inference from site-directed mutagenesis studies. Int J Mol Med. 2001 Feb; 7(2):163-8. PMID: 11172619.
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    263. Shi Z, Azuma A, Sampath D, Li YX, Huang P, Plunkett W. S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine. Cancer Res. 2001 Feb 1; 61(3):1065-72. PMID: 11221834.
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    264. Jabbur JR, Huang P, Zhang W. DNA damage-induced phosphorylation of p53 at serine 20 correlates with p21 and Mdm-2 induction in vivo. Oncogene. 2000 Dec 14; 19(54):6203-8. PMID: 11175334.
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    265. Shao JY, Wang HY, Huang XM, Feng QS, Huang P, Feng BJ, Huang LX, Yu XJ, Li JT, Hu LF, Ernberg I, Zeng YX. Genome-wide allelotype analysis of sporadic primary nasopharyngeal carcinoma from southern China. Int J Oncol. 2000 Dec; 17(6):1267-75. PMID: 11078815.
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    266. Huang P, Feng L, Oldham EA, Keating MJ, Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature. 2000 Sep 21; 407(6802):390-5. PMID: 11014196.
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    267. Xu F, Xia W, Luo RZ, Peng H, Zhao S, Dai J, Long Y, Zou L, Le W, Liu J, Parlow AF, Hung MC, Bast RC, Yu Y. The human ARHI tumor suppressor gene inhibits lactation and growth in transgenic mice. Cancer Res. 2000 Sep 1; 60(17):4913-20. PMID: 10987306.
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    268. Huang P, Sandoval A, Van Den Neste E, Keating MJ, Plunkett W. Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine. Leukemia. 2000 Aug; 14(8):1405-13. PMID: 10942236.
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    269. Feng L, Achanta G, Pelicano H, Zhang W, Plunkett W, Huang P. Role of p53 in cellular response to anticancer nucleoside analog-induced DNA damage. Int J Mol Med. 2000 Jun; 5(6):597-604. PMID: 10812007.
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    270. Lu SC, Wu WH, Lee CA, Chou HF, Lee HR, Huang PC. LDL of Taiwanese vegetarians are less oxidizable than those of omnivores. J Nutr. 2000 Jun; 130(6):1591-6. PMID: 10827215.
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    271. Oldham EA, Li C, Ke S, Wallace S, Huang P. Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells. Int J Oncol. 2000 Jan; 16(1):125-32. PMID: 10601557.
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    272. Huang PC, Yau KI, Wu MZ, Huang SF. Neonatal intestinal perforation caused by congenital defect of the small intestinal musculature: report of one case. Acta Paediatr Taiwan. 1999 Jul-Aug; 40(4):271-3. PMID: 10910628.
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    273. Tzang BS, Lai YC, Hsu M, Chang HW, Chang CC, Huang PC, Liu YC. Function and sequence analyses of tumor suppressor gene p53 of CHO.K1 cells. DNA Cell Biol. 1999 Apr; 18(4):315-21. PMID: 10235114.
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    274. Huang P. Excision of mismatched nucleotides from DNA: a potential mechanism for enhancing DNA replication fidelity by the wild-type p53 protein. Oncogene. 1998 Jul 23; 17(3):261-70. PMID: 9690508.
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    275. Huang P, Ballal K, Plunkett W. Biochemical characterization of the protein activity responsible for high molecular weight DNA fragmentation during drug-induced apoptosis. Cancer Res. 1997 Aug 15; 57(16):3407-14. PMID: 9270006.
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    276. Gandhi V, Huang P, Chapman AJ, Chen F, Plunkett W. Incorporation of fludarabine and 1-beta-D-arabinofuranosylcytosine 5'-triphosphates by DNA polymerase alpha: affinity, interaction, and consequences. Clin Cancer Res. 1997 Aug; 3(8):1347-55. PMID: 9815818.
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    277. Consoli U, Li H, Huang P, Kobayashi T, Andreeff M, Levin V, Zhang W. Enhancement of apoptosis in irradiated glioblastoma cells by pentoxifylline. Oncol Rep. 1997 Jul-Aug; 4(4):673-8. PMID: 21590120.
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    278. Iwasaki H, Huang P, Keating MJ, Plunkett W. Differential incorporation of ara-C, gemcitabine, and fludarabine into replicating and repairing DNA in proliferating human leukemia cells. Blood. 1997 Jul 1; 90(1):270-8. PMID: 9207462.
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    279. Plunkett W, Huang P, Searcy CE, Gandhi V. Gemcitabine: preclinical pharmacology and mechanisms of action. Semin Oncol. 1996 Oct; 23(5 Suppl 10):3-15. PMID: 8893876.
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    280. Kamiya K, Huang P, Plunkett W. Inhibition of the 3' --> 5' exonuclease of human DNA polymerase epsilon by fludarabine-terminated DNA. J Biol Chem. 1996 Aug 9; 271(32):19428-35. PMID: 8702631.
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    281. Seymour JF, Huang P, Plunkett W, Gandhi V. Influence of fludarabine on pharmacokinetics and pharmacodynamics of cytarabine: implications for a continuous infusion schedule. Clin Cancer Res. 1996 Apr; 2(4):653-8. PMID: 9816215.
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    282. Plunkett W, Huang P, Gandhi V. Preclinical characteristics of gemcitabine. Anticancer Drugs. 1995 Dec; 6 Suppl 6:7-13. PMID: 8718419.
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    283. Huang P, Robertson LE, Wright S, Plunkett W. High molecular weight DNA fragmentation: a critical event in nucleoside analogue-induced apoptosis in leukemia cells. Clin Cancer Res. 1995 Sep; 1(9):1005-13. PMID: 9816073.
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    284. Huang P, Plunkett W. Induction of apoptosis by gemcitabine. Semin Oncol. 1995 Aug; 22(4 Suppl 11):19-25. PMID: 7481840.
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    285. Plunkett W, Huang P, Xu YZ, Heinemann V, Grunewald R, Gandhi V. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin Oncol. 1995 Aug; 22(4 Suppl 11):3-10. PMID: 7481842.
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    286. Gandhi V, Mineishi S, Huang P, Yang Y, Chubb S, Chapman AJ, Nowak BJ, Hertel LW, Plunkett W. Difluorodeoxyguanosine: cytotoxicity, metabolism, and actions on DNA synthesis in human leukemia cells. Semin Oncol. 1995 Aug; 22(4 Suppl 11):61-7. PMID: 7481847.
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    287. Gandhi V, Mineishi S, Huang P, Chapman AJ, Yang Y, Chen F, Nowak B, Chubb S, Hertel LW, Plunkett W. Cytotoxicity, metabolism, and mechanisms of action of 2',2'-difluorodeoxyguanosine in Chinese hamster ovary cells. Cancer Res. 1995 Apr 1; 55(7):1517-24. PMID: 7533664.
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    288. Xu YZ, Huang P, Plunkett W. Functional compartmentation of dCTP pools. Preferential utilization of salvaged deoxycytidine for DNA repair in human lymphoblasts. J Biol Chem. 1995 Jan 13; 270(2):631-7. PMID: 7822289.
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    289. Huang P, Plunkett W. Fludarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event. Cancer Chemother Pharmacol. 1995; 36(3):181-8. PMID: 7781136.
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    290. Gandhi V, Huang P, Plunkett W. Fludarabine inhibits DNA replication: a rationale for its use in the treatment of acute leukemias. Leuk Lymphoma. 1994; 14 Suppl 2:3-9. PMID: 7881348.
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    291. Plunkett W, Gandhi V, Huang P, Robertson LE, Yang LY, Gregoire V, Estey E, Keating MJ. Fludarabine: pharmacokinetics, mechanisms of action, and rationales for combination therapies. Semin Oncol. 1993 Oct; 20(5 Suppl 7):2-12. PMID: 8235690.
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    292. Huang PC, Gaitan AE, Hao Y, Petters RM, Wong F. Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8484-8. PMID: 8378322.
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    293. Cherian MG, Huang PC, Klaassen CD, Liu YP, Longfellow DG, Waalkes MP. National Cancer Institute workshop on the possible roles of metallothionein in carcinogenesis. Cancer Res. 1993 Feb 15; 53(4):922-5. PMID: 8428370.
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    294. Huang P, Plunkett W. A quantitative assay for fragmented DNA in apoptotic cells. Anal Biochem. 1992 Nov 15; 207(1):163-7. PMID: 1489090.
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    295. Huang P, Farquhar D, Plunkett W. Selective action of 2',3'-didehydro-2',3'-dideoxythymidine triphosphate on human immunodeficiency virus reverse transcriptase and human DNA polymerases. J Biol Chem. 1992 Feb 5; 267(4):2817-22. PMID: 1370834.
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    296. Yang SW, Huang P, Plunkett W, Becker FF, Chan JY. Dual mode of inhibition of purified DNA ligase I from human cells by 9-beta-D-arabinofuranosyl-2-fluoroadenine triphosphate. J Biol Chem. 1992 Feb 5; 267(4):2345-9. PMID: 1310314.
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    297. Huang P, Chubb S, Hertel LW, Grindey GB, Plunkett W. Action of 2',2'-difluorodeoxycytidine on DNA synthesis. Cancer Res. 1991 Nov 15; 51(22):6110-7. PMID: 1718594.
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    298. Hung SH, Yu CW, Chou TM, Huang PC, Lin LY. Molecular cloning of Chinese hamster metallothionein II gene and its 5' flanking region. Biochim Biophys Acta. 1991 Oct 8; 1090(2):255-8. PMID: 1932120.
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    299. Huang P, Plunkett W. Action of 9-beta-D-arabinofuranosyl-2-fluoroadenine on RNA metabolism. Mol Pharmacol. 1991 Apr; 39(4):449-55. PMID: 1708088.
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    300. Gandhi V, Huang P, Xu YZ, Heinemann V, Plunkett W. Metabolism and action of 2',2'-difluorodeoxycytidine: self-potentiation of cytotoxicity. Adv Exp Med Biol. 1991; 309A:125-30. PMID: 1789190.
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    301. Lin LY, Liu LF, Tam MF, Huang PC, Vestling M, Fenselau C. Primary sequence of duck metallothionein. Biochim Biophys Acta. 1990 Oct 18; 1041(1):31-5. PMID: 2223844.
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    302. Plunkett W, Huang P, Gandhi V. Metabolism and action of fludarabine phosphate. Semin Oncol. 1990 Oct; 17(5 Suppl 8):3-17. PMID: 1699280.
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    303. Huang P, Chubb S, Plunkett W. Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity. J Biol Chem. 1990 Sep 25; 265(27):16617-25. PMID: 1697861.
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    304. Huang P, Farquhar D, Plunkett W. Selective action of 3'-azido-3'-deoxythymidine 5'-triphosphate on viral reverse transcriptases and human DNA polymerases. J Biol Chem. 1990 Jul 15; 265(20):11914-8. PMID: 1694849.
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    305. Lin LY, Lin WC, Huang PC. Pigeon metallothionein consists of two species. Biochim Biophys Acta. 1990 Feb 9; 1037(2):248-55. PMID: 2407296.
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    306. Huang P, Siciliano MJ, Plunkett W. Gene deletion, a mechanism of induced mutation by arabinosyl nucleosides. Mutat Res. 1989 Feb; 210(2):291-301. PMID: 2911256.
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    307. Huang P, Plunkett W. Phosphorolytic cleavage of 2-fluoroadenine from 9-beta-D-arabinofuranosyl-2-fluoroadenine by Escherichia coli. A pathway for 2-fluoro-ATP production. Biochem Pharmacol. 1987 Sep 15; 36(18):2945-50. PMID: 3307790.
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    308. Huang PC, Morris S, Dinman J, Pine R, Smith B. Role of metallothionein in detoxification and tolerance to transition metals. Experientia Suppl. 1987; 52:439-46. PMID: 2959533.
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    309. Savino W, Huang PC, Corrigan A, Berrih S, Dardenne M. Thymic hormone-containing cells. V. Immunohistological detection of metallothionein within the cells bearing thymulin (a zinc-containing hormone) in human and mouse thymuses. J Histochem Cytochem. 1984 Sep; 32(9):942-6. PMID: 6379040.
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    310. Sheridan RB, Huang PC. Endonucleolytic activity for gamma-irradiated DNA in normal and ataxia telangiectasia fibroblast cell extracts. Mutat Res. 1979 Dec; 63(2):387-92. PMID: 522879.
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    311. Goetz G, Esmailzadeh AK, Huang PC. Histone H5 in nucleated erythrocytes of fish as determined by radioimmunoassay. Biochim Biophys Acta. 1978 Jan 26; 517(1):236-45. PMID: 623759.
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    312. Chi RK, Scocca JJ, Huang PC. An evaluation of Tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation. Mutat Res. 1978 Jan; 49(1):1-8. PMID: 340938.
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    313. Vincent RA, Huang PC. The proportion of cells labeled with tritiated thymidine as a function of population doubling level in cultures of fetal, adult, mutant, and tumor origin. Exp Cell Res. 1976 Oct 1; 102(1):31-42. PMID: 976344.
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    314. Lee KS, Huang PC, Cohen BH. Further resolution of adult chick hemoglobins by isoelectric focusing in polyacrylamide gel. Biochim Biophys Acta. 1976 Mar 18; 427(1):178-96. PMID: 1259997.
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    315. Huang PC, Pharo RL. A simple method for the purification of the mitochondrial NADH dehydrogenase. Biochim Biophys Acta. 1971 Aug 6; 245(1):240-4. PMID: 4332099.
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    316. Cooper AD, Huang PC. Partial denaturation of Haemophilus influenzae DNA by alkali. Biochim Biophys Acta. 1971 May 13; 238(2):180-5. PMID: 5315136.
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    317. Cooper AD, Huang PC. Differential denaturation of Haemophilus influenzae DNA. Biochim Biophys Acta. 1971 Mar 11; 232(2):234-45. PMID: 5313787.
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    318. Huang PC, Tung TC, Lue HC, Lee CY, Wei H. Feeding of infants with full-fat soya bean-rice foods. J Trop Pediatr Afr Child Health. 1967 Mar; 13(1):27-36. PMID: 5298827.
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    319. Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism. Stem Cell Research and Therapy.
    320. SIRT2 deacetylates and inhibits the peroxidase activity of peroxiredoxin-1 to sensitize breast cancer cells to oxidant stress-inducing agents. Cancer Research. 76:5467-5478.
    321. Intracellular metabolism and action of an antitumor nucleoside, 2'-C- cyano-2'-deoxy-1-β-D-arabinofuranosylcytosine (CNDAC). Nucleosides and Nucleotides. 16:1037-1039.
    322. Erratum. Cell. 111:1055.
    323. Apoptosis in chronic lymphocytic leukemia. Cancer Bulletin. 46:130-135.
    324. Metabolic alterations and drug sensitivity of tyrosine kinase inhibitor resistant leukemia cells with a FLT3/ITD mutation. Cancer Letters. 377:149-157.
    325. Oxidative stress, cell proliferation, and apoptosis. 309-332.
    326. ACS Symposium Series. 639:265-278.
    327. Oxidative stress and drug resistance in cancer. 137-175.
    328. Models of reactive oxygen species in cancer. Drug Discovery Today: Disease Models. 4:67-73.
    329. Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with an antiangina drug perhexiline. Oncogene.
    330. Identification of NDUFAF1 in mediating K-Ras induced mitochondrial dysfunction by a proteomic screening approach. Oncotarget. 6:3947-3962.
    331. Superoxide dismutase. Expert Opinion on Therapeutic Targets. 5:697-710.
    332. Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression. International Journal of Oncology. 50:252-262.
    333. Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism. Oncotarget. 7:71378-71389.
    334. Correction to Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 [Molecular Cell 61, 520-534, (2016)]. Molecular Cell. 61:640.
    335. Cu/Pd-Catalyzed Cascade Reactions of Cyclic Diaryliodoniums and Alkynes - Access to Fluorenes with Conjugate Enynes/Dienes. European Journal of Organic Chemistry. 2016:1110-1118.
    336. Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress. Free Radical Biology and Medicine. 99:436-450.
    337. Cancer stem cells, metabolism, and therapeutic significance. Tumor Biology. 1-8.
    338. Gemcitabine. Nucleosides and Nucleotides. 16:1261-1270.
    339. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget. 6:21148-21158.
    340. Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression. Journal of Experimental and Clinical Cancer Research. 35.
    341. Chinese Journal of Cancer. 34.
    342. Synthesis of carbazoles via one-pot copper-catalyzed amine insertion into cyclic diphenyleneiodoniums as a strategy to generate a drug-like chemical library. Advanced Synthesis and Catalysis. 355:2172-2178.
    343. Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53. Mitochondrion. 31:33-39.
    344. N-Benzyldithiocarbamate Salts as Sulfur Sources to Access Tricyclic Thioheterocycles Mediated by Copper Species. Advanced Synthesis and Catalysis.
    345. Synthesis and biological evaluation of santacruzamate A and analogs as potential anticancer agents. RSC Advances. 5:1109-1112.
    346. MGMT in colorectal cancer. Tumor Biology. 1-14.
    347. Targeting mitochondria of cancer cells. 183-210.
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