InstitutionMD Anderson
DepartmentTranslational Molecular Pathology
Address2130 W Holcombe Blvd
Houston TX 77030
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fu J, Ling J, Li CF, Tsai CL, Yin W, Hou J, Chen P, Cao Y, Kang Y, Sun Y, Xia X, Jiang Z, Furukawa K, Lu Y, Wu M, Huang Q, Yao J, Hawke DH, Pan BF, Zhao J, Huang J, Wang H, Bahassi EIM, Stambrook PJ, Huang P, Fleming JB, Maitra A, Tainer JA, Hung MC, Lin C, Chiao PJ. Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer. Nat Commun. 2024 Apr 11; 15(1):3149. PMID: 38605037; PMCID: PMC11009390.
    2. Salehjahromi M, Karpinets TV, Sujit SJ, Qayati M, Chen P, Aminu M, Saad MB, Bandyopadhyay R, Hong L, Sheshadri A, Lin J, Antonoff MB, Sepesi B, Ostrin EJ, Toumazis I, Huang P, Cheng C, Cascone T, Vokes NI, Behrens C, Siewerdsen JH, Hazle JD, Chang JY, Zhang J, Lu Y, Godoy MCB, Chung C, Jaffray D, Wistuba I, Lee JJ, Vaporciyan AA, Gibbons DL, Gladish G, Heymach JV, Wu CC, Zhang J, Wu J. Synthetic PET from CT improves diagnosis and prognosis for lung cancer: Proof of concept. Cell Rep Med. 2024 Mar 19; 5(3):101463. PMID: 38471502; PMCID: PMC10983039.
      Citations:    Fields:    Translation:Humans
    3. Lv X, Lu X, Cao J, Luo Q, Ding Y, Peng F, Pataer A, Lu D, Han D, Malmberg E, Chan DW, Wang X, Savage SR, Mao S, Yu J, Peng F, Yan L, Meng H, Maneix L, Han Y, Chen Y, Yao W, Chang EC, Catic A, Lin X, Miles G, Huang P, Sun Z, Burt B, Wang H, Wang J, Yao QC, Zhang B, Roth JA, O'Malley BW, Ellis MJ, Rimawi MF, Ying H, Chen X. Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors. Science. 2023 09 08; 381(6662):eabn4180. PMID: 37676964; PMCID: PMC10720158.
      Citations: 2     Fields:    Translation:HumansCells
    4. Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H, Zhuang L, Chen G, Xiao ZD, Hung MC, Chen J, Huang P, Li W, Gan B. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018 10; 20(10):1181-1192. PMID: 30202049; PMCID: PMC6170713.
      Citations: 208     Fields:    Translation:HumansAnimalsCells
    5. Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W. Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy. Cell Metab. 2018 May 01; 27(5):977-987.e4. PMID: 29628419; PMCID: PMC5932208.
      Citations: 183     Fields:    Translation:HumansAnimalsCells
    6. Liu J, Chen G, Pelicano H, Liao J, Huang J, Feng L, Keating MJ, Huang P. Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism. Oncotarget. 2016 Nov 01; 7(44):71378-71389. PMID: 27655686; PMCID: PMC5342085.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    7. Ogasawara MA, Liu J, Pelicano H, Hammoudi N, Croce CM, Keating MJ, Huang P. Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53. Mitochondrion. 2016 Nov; 31:33-39. PMID: 27650502; PMCID: PMC5108679.
      Citations: 6     Fields:    Translation:HumansAnimals
    8. Fiskus W, Coothankandaswamy V, Chen J, Ma H, Ha K, Saenz DT, Krieger SS, Mill CP, Sun B, Huang P, Mumm JS, Melnick AM, Bhalla KN. SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents. Cancer Res. 2016 09 15; 76(18):5467-78. PMID: 27503926; PMCID: PMC5345574.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    9. Redis RS, Vela LE, Lu W, Ivan C, Rodriguez-Aguayo C, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Calin GA, Ferreira de Oliveira J, Adamoski D, Gaf? R, Ambrosio ALB, Gomes Dias SM. Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2. Mol Cell. 2016 Feb 18; 61(4):520-534. PMID: 26853146; PMCID: PMC4982398.
      Citations: 76     Fields:    Translation:HumansCells
    10. Ju HQ, Gocho T, Aguilar M, Wu M, Zhuang ZN, Fu J, Yanaga K, Huang P, Chiao PJ. Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation. Mol Cancer Ther. 2015 Mar; 14(3):788-98. PMID: 25527634.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    11. Chang Z, Ju H, Ling J, Zhuang Z, Li Z, Wang H, Fleming JB, Freeman JW, Yu D, Huang P, Chiao PJ. Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis. PLoS One. 2014; 9(7):e101452. PMID: 25029561; PMCID: PMC4100754.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    12. Zhu D, Wu Y, Wu B, Luo B, Ganesan A, Wu FH, Pi R, Huang P, Wen S. Three-component Pd/Cu-catalyzed cascade reactions of cyclic iodoniums, alkynes, and boronic acids: an approach to methylidenefluorenes. Org Lett. 2014 May 02; 16(9):2350-3. PMID: 24742135.
      Citations: 5     Fields:    Translation:Cells
    13. Schauer IG, Zhang J, Xing Z, Guo X, Mercado-Uribe I, Sood AK, Huang P, Liu J. Interleukin-1? promotes ovarian tumorigenesis through a p53/NF-?B-mediated inflammatory response in stromal fibroblasts. Neoplasia. 2013 Apr; 15(4):409-20. PMID: 23555186; PMCID: PMC3612913.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    14. Lu W, Hu Y, Chen G, Chen Z, Zhang H, Wang F, Feng L, Pelicano H, Wang H, Keating MJ, Liu J, McKeehan W, Wang H, Luo Y, Huang P. Novel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapy. PLoS Biol. 2012; 10(5):e1001326. PMID: 22589701; PMCID: PMC3348157.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    15. Zhang W, Trachootham D, Liu J, Chen G, Pelicano H, Garcia-Prieto C, Lu W, Burger JA, Croce CM, Plunkett W, Keating MJ, Huang P. Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia. Nat Cell Biol. 2012 Feb 19; 14(3):276-86. PMID: 22344033; PMCID: PMC3290742.
      Citations: 161     Fields:    Translation:HumansAnimalsCells
    16. Chen G, Chen Z, Hu Y, Huang P. Inhibition of mitochondrial respiration and rapid depletion of mitochondrial glutathione by ?-phenethyl isothiocyanate: mechanisms for anti-leukemia activity. Antioxid Redox Signal. 2011 Dec 15; 15(12):2911-21. PMID: 21827296; PMCID: PMC3201634.
      Citations: 37     Fields:    Translation:HumansCells
    17. Hammoudi N, Ahmed KB, Garcia-Prieto C, Huang P. Metabolic alterations in cancer cells and therapeutic implications. Chin J Cancer. 2011 Aug; 30(8):508-25. PMID: 21801600; PMCID: PMC4013402.
      Citations: 39     Fields:    Translation:HumansCells
    18. Zhang W, Huang P. Cancer-stromal interactions: role in cell survival, metabolism and drug sensitivity. Cancer Biol Ther. 2011 Jan 15; 11(2):150-6. PMID: 21191189; PMCID: PMC3230306.
      Citations: 23     Fields:    Translation:HumansCells
    19. Chen G, Wang F, Trachootham D, Huang P. Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds. Mitochondrion. 2010 Nov; 10(6):614-25. PMID: 20713185; PMCID: PMC3085019.
      Citations: 31     Fields:    Translation:HumansCells
    20. Wang F, Ogasawara MA, Huang P. Small mitochondria-targeting molecules as anti-cancer agents. Mol Aspects Med. 2010 Feb; 31(1):75-92. PMID: 19995573; PMCID: PMC2836415.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    21. Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov. 2009 Jul; 8(7):579-91. PMID: 19478820.
      Citations: 1480     Fields:    Translation:HumansAnimalsCells
    22. Chen G, Izzo J, Demizu Y, Wang F, Guha S, Wu X, Hung MC, Ajani JA, Huang P. Different redox states in malignant and nonmalignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol. Antioxid Redox Signal. 2009 May; 11(5):1083-95. PMID: 19187006; PMCID: PMC2842128.
      Citations: 14     Fields:    Translation:HumansCells
    23. Chen Z, Zhang H, Lu W, Huang P. Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. Biochim Biophys Acta. 2009 May; 1787(5):553-60. PMID: 19285479; PMCID: PMC2731236.
      Citations: 90     Fields:    Translation:HumansCells
    24. Izzo JG, Wu X, Wu TT, Huang P, Lee JS, Liao Z, Lee JH, Bhutani MS, Hofstetter W, Maru D, Hung MC, Ajani JA. Therapy-induced expression of NF-kappaB portends poor prognosis in patients with localized esophageal cancer undergoing preoperative chemoradiation. Dis Esophagus. 2009; 22(2):127-32. PMID: 19021681.
      Citations: 6     Fields:    Translation:Humans
    25. Trachootham D, Lu W, Ogasawara MA, Nilsa RD, Huang P. Redox regulation of cell survival. Antioxid Redox Signal. 2008 Aug; 10(8):1343-74. PMID: 18522489; PMCID: PMC2932530.
      Citations: 546     Fields:    Translation:HumansAnimalsCells
    26. Hu W, Hofstetter W, Guo W, Li H, Pataer A, Peng HH, Guo ZS, Bartlett DL, Lin A, Swisher SG, Fang B. JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase. Cancer Gene Ther. 2008 Sep; 15(9):616-24. PMID: 18535619; PMCID: PMC2553758.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    27. Demizu Y, Sasaki R, Trachootham D, Pelicano H, Colacino JA, Liu J, Huang P. Alterations of cellular redox state during NNK-induced malignant transformation and resistance to radiation. Antioxid Redox Signal. 2008 May; 10(5):951-61. PMID: 18257743; PMCID: PMC2717788.
      Citations: 7     Fields:    Translation:HumansCells
    28. Chen Z, Lu W, Garcia-Prieto C, Huang P. The Warburg effect and its cancer therapeutic implications. J Bioenerg Biomembr. 2007 Jun; 39(3):267-74. PMID: 17551814.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    29. Lu W, Ogasawara MA, Huang P. Models of reactive oxygen species in cancer. Drug Discov Today Dis Models. 2007; 4(2):67-73. PMID: 18591999; PMCID: PMC2390932.
      Citations: 21     
    30. Xu RH, Du M, Feng L, Sasaki R, Carew JS, Hu Y, Ramdas L, Hu L, Keating MJ, Zhang W, Plunkett W, Huang P, Pelicano H. Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism. J Cell Biol. 2006 Dec 18; 175(6):913-23. PMID: 17158952; PMCID: PMC2064701.
      Citations: 173     Fields:    Translation:HumansCells
    31. Achanta G, Modzelewska A, Feng L, Khan SR, Huang P. A boronic-chalcone derivative exhibits potent anticancer activity through inhibition of the proteasome. Mol Pharmacol. 2006 Jul; 70(1):426-33. PMID: 16636137.
      Citations: 24     Fields:    Translation:HumansCells
    32. Lu Z, Luo RZ, Peng H, Huang M, Nishmoto A, Hunt KK, Helin K, Liao WS, Yu Y. E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer. Oncogene. 2006 Jan 12; 25(2):230-9. PMID: 16158053.
      Citations: 26     Fields:    Translation:HumansCells
    33. Nawrocki ST, Carew JS, Dunner K, Boise LH, Chiao PJ, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Res. 2005 Dec 15; 65(24):11510-9. PMID: 16357160.
      Citations: 115     Fields:    Translation:HumansCells
    34. Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Dunner K, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res. 2005 Dec 15; 65(24):11658-66. PMID: 16357177.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    35. Achanta G, Sasaki R, Feng L, Carew JS, Lu W, Pelicano H, Keating MJ, Huang P. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. EMBO J. 2005 Oct 05; 24(19):3482-92. PMID: 16163384; PMCID: PMC1276176.
      Citations: 133     Fields:    Translation:HumansCells
    36. Fu L, Pelicano H, Liu J, Huang P, Lee C. The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell. 2002 Oct 04; 111(1):41-50. PMID: 12372299.
      Citations: 516     Fields:    Translation:AnimalsCells
    37. Achanta G, Pelicano H, Feng L, Plunkett W, Huang P. Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage. Cancer Res. 2001 Dec 15; 61(24):8723-9. PMID: 11751391.
      Citations: 33     Fields:    Translation:HumansCells
    38. Hileman EA, Achanta G, Huang P. Superoxide dismutase: an emerging target for cancer therapeutics. Expert Opin Ther Targets. 2001 Dec; 5(6):697-710. PMID: 12540279.
      Citations: 24     Fields:    
    39. Azuma A, Huang P, Matsuda A, Plunkett W. Cellular pharmacokinetics and pharmacodynamics of the deoxycytidine analog 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC). Biochem Pharmacol. 2001 Jun 15; 61(12):1497-507. PMID: 11377379.
      Citations: 7     Fields:    Translation:HumansCells
    40. Azuma A, Huang P, Matsuda A, Plunkett W. 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest. Mol Pharmacol. 2001 Apr; 59(4):725-31. PMID: 11259616.
      Citations: 33     Fields:    Translation:HumansCells
    41. Shi Z, Azuma A, Sampath D, Li YX, Huang P, Plunkett W. S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine. Cancer Res. 2001 Feb 01; 61(3):1065-72. PMID: 11221834.
      Citations: 35     Fields:    Translation:HumansCells
    42. Jabbur JR, Huang P, Zhang W. Enhancement of the antiproliferative function of p53 by phosphorylation at serine 20: an inference from site-directed mutagenesis studies. Int J Mol Med. 2001 Feb; 7(2):163-8. PMID: 11172619.
      Citations: 3     Fields:    Translation:HumansCells
    43. Shao JY, Wang HY, Huang XM, Feng QS, Huang P, Feng BJ, Huang LX, Yu XJ, Li JT, Hu LF, Ernberg I, Zeng YX. Genome-wide allelotype analysis of sporadic primary nasopharyngeal carcinoma from southern China. Int J Oncol. 2000 Dec; 17(6):1267-75. PMID: 11078815.
      Citations: 22     Fields:    Translation:HumansCells
    44. Huang P, Feng L, Oldham EA, Keating MJ, Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature. 2000 Sep 21; 407(6802):390-5. PMID: 11014196.
      Citations: 191     Fields:    Translation:HumansCells
    45. Xu F, Xia W, Luo RZ, Peng H, Zhao S, Dai J, Long Y, Zou L, Le W, Liu J, Parlow AF, Hung MC, Bast RC, Yu Y. The human ARHI tumor suppressor gene inhibits lactation and growth in transgenic mice. Cancer Res. 2000 Sep 01; 60(17):4913-20. PMID: 10987306.
      Citations: 15     Fields:    Translation:AnimalsCells
    46. Feng L, Achanta G, Pelicano H, Zhang W, Plunkett W, Huang P. Role of p53 in cellular response to anticancer nucleoside analog-induced DNA damage. Int J Mol Med. 2000 Jun; 5(6):597-604. PMID: 10812007.
      Citations: 9     Fields:    
    47. Oldham EA, Li C, Ke S, Wallace S, Huang P. Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells. Int J Oncol. 2000 Jan; 16(1):125-32. PMID: 10601557.
      Citations: 12     Fields:    Translation:HumansCells
    48. Huang P, Ballal K, Plunkett W. Biochemical characterization of the protein activity responsible for high molecular weight DNA fragmentation during drug-induced apoptosis. Cancer Res. 1997 Aug 15; 57(16):3407-14. PMID: 9270006.
      Citations: 8     Fields:    Translation:HumansCells
    49. Gandhi V, Huang P, Chapman AJ, Chen F, Plunkett W. Incorporation of fludarabine and 1-beta-D-arabinofuranosylcytosine 5'-triphosphates by DNA polymerase alpha: affinity, interaction, and consequences. Clin Cancer Res. 1997 Aug; 3(8):1347-55. PMID: 9815818.
      Citations: 9     Fields:    Translation:HumansCells
    50. Plunkett W, Huang P, Searcy CE, Gandhi V. Gemcitabine: preclinical pharmacology and mechanisms of action. Semin Oncol. 1996 Oct; 23(5 Suppl 10):3-15. PMID: 8893876.
      Citations: 96     Fields:    Translation:HumansAnimals
    51. Kamiya K, Huang P, Plunkett W. Inhibition of the 3' --> 5' exonuclease of human DNA polymerase epsilon by fludarabine-terminated DNA. J Biol Chem. 1996 Aug 09; 271(32):19428-35. PMID: 8702631.
      Citations: 6     Fields:    Translation:HumansCells
    52. Seymour JF, Huang P, Plunkett W, Gandhi V. Influence of fludarabine on pharmacokinetics and pharmacodynamics of cytarabine: implications for a continuous infusion schedule. Clin Cancer Res. 1996 Apr; 2(4):653-8. PMID: 9816215.
      Citations: 12     Fields:    Translation:HumansCells
    53. Plunkett W, Huang P, Gandhi V. Preclinical characteristics of gemcitabine. Anticancer Drugs. 1995 Dec; 6 Suppl 6:7-13. PMID: 8718419.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    54. Huang P, Robertson LE, Wright S, Plunkett W. High molecular weight DNA fragmentation: a critical event in nucleoside analogue-induced apoptosis in leukemia cells. Clin Cancer Res. 1995 Sep; 1(9):1005-13. PMID: 9816073.
      Citations: 14     Fields:    Translation:HumansCells
    55. Huang P, Plunkett W. Induction of apoptosis by gemcitabine. Semin Oncol. 1995 Aug; 22(4 Suppl 11):19-25. PMID: 7481840.
      Citations: 39     Fields:    Translation:HumansCells
    56. Plunkett W, Huang P, Xu YZ, Heinemann V, Grunewald R, Gandhi V. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin Oncol. 1995 Aug; 22(4 Suppl 11):3-10. PMID: 7481842.
      Citations: 218     Fields:    Translation:HumansAnimalsCells
    57. Gandhi V, Mineishi S, Huang P, Yang Y, Chubb S, Chapman AJ, Nowak BJ, Hertel LW, Plunkett W. Difluorodeoxyguanosine: cytotoxicity, metabolism, and actions on DNA synthesis in human leukemia cells. Semin Oncol. 1995 Aug; 22(4 Suppl 11):61-7. PMID: 7481847.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    58. Gandhi V, Mineishi S, Huang P, Chapman AJ, Yang Y, Chen F, Nowak B, Chubb S, Hertel LW, Plunkett W. Cytotoxicity, metabolism, and mechanisms of action of 2',2'-difluorodeoxyguanosine in Chinese hamster ovary cells. Cancer Res. 1995 Apr 01; 55(7):1517-24. PMID: 7533664.
      Citations: 9     Fields:    Translation:AnimalsCells
    59. Xu YZ, Huang P, Plunkett W. Functional compartmentation of dCTP pools. Preferential utilization of salvaged deoxycytidine for DNA repair in human lymphoblasts. J Biol Chem. 1995 Jan 13; 270(2):631-7. PMID: 7822289.
      Citations: 9     Fields:    Translation:HumansCells
    60. Huang P, Plunkett W. Fludarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event. Cancer Chemother Pharmacol. 1995; 36(3):181-8. PMID: 7781136.
      Citations: 38     Fields:    Translation:HumansCells
    61. Gandhi V, Huang P, Plunkett W. Fludarabine inhibits DNA replication: a rationale for its use in the treatment of acute leukemias. Leuk Lymphoma. 1994; 14 Suppl 2:3-9. PMID: 7881348.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    62. Plunkett W, Gandhi V, Huang P, Robertson LE, Yang LY, Gregoire V, Estey E, Keating MJ. Fludarabine: pharmacokinetics, mechanisms of action, and rationales for combination therapies. Semin Oncol. 1993 Oct; 20(5 Suppl 7):2-12. PMID: 8235690.
      Citations: 30     Fields:    Translation:Humans
    63. Huang P, Plunkett W. A quantitative assay for fragmented DNA in apoptotic cells. Anal Biochem. 1992 Nov 15; 207(1):163-7. PMID: 1489090.
      Citations: 6     Fields:    Translation:HumansCells
    64. Yang SW, Huang P, Plunkett W, Becker FF, Chan JY. Dual mode of inhibition of purified DNA ligase I from human cells by 9-beta-D-arabinofuranosyl-2-fluoroadenine triphosphate. J Biol Chem. 1992 Feb 05; 267(4):2345-9. PMID: 1310314.
      Citations: 19     Fields:    Translation:HumansCells
    65. Huang P, Farquhar D, Plunkett W. Selective action of 2',3'-didehydro-2',3'-dideoxythymidine triphosphate on human immunodeficiency virus reverse transcriptase and human DNA polymerases. J Biol Chem. 1992 Feb 05; 267(4):2817-22. PMID: 1370834.
      Citations: 12     Fields:    Translation:HumansCells
    66. Huang P, Chubb S, Hertel LW, Grindey GB, Plunkett W. Action of 2',2'-difluorodeoxycytidine on DNA synthesis. Cancer Res. 1991 Nov 15; 51(22):6110-7. PMID: 1718594.
      Citations: 225     Fields:    Translation:HumansCells
    67. Huang P, Plunkett W. Action of 9-beta-D-arabinofuranosyl-2-fluoroadenine on RNA metabolism. Mol Pharmacol. 1991 Apr; 39(4):449-55. PMID: 1708088.
      Citations: 13     Fields:    Translation:Cells
    68. Gandhi V, Huang P, Xu YZ, Heinemann V, Plunkett W. Metabolism and action of 2',2'-difluorodeoxycytidine: self-potentiation of cytotoxicity. Adv Exp Med Biol. 1991; 309A:125-30. PMID: 1789190.
      Citations: 5     Fields:    Translation:HumansCells
    69. Plunkett W, Huang P, Gandhi V. Metabolism and action of fludarabine phosphate. Semin Oncol. 1990 Oct; 17(5 Suppl 8):3-17. PMID: 1699280.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    70. Huang P, Chubb S, Plunkett W. Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity. J Biol Chem. 1990 Sep 25; 265(27):16617-25. PMID: 1697861.
      Citations: 56     Fields:    Translation:HumansCells
    71. Huang P, Farquhar D, Plunkett W. Selective action of 3'-azido-3'-deoxythymidine 5'-triphosphate on viral reverse transcriptases and human DNA polymerases. J Biol Chem. 1990 Jul 15; 265(20):11914-8. PMID: 1694849.
      Citations: 34     Fields:    Translation:HumansCells
    72. Huang P, Siciliano MJ, Plunkett W. Gene deletion, a mechanism of induced mutation by arabinosyl nucleosides. Mutat Res. 1989 Feb; 210(2):291-301. PMID: 2911256.
      Citations: 7     Fields:    Translation:AnimalsCells
    73. Huang P, Plunkett W. Phosphorolytic cleavage of 2-fluoroadenine from 9-beta-D-arabinofuranosyl-2-fluoroadenine by Escherichia coli. A pathway for 2-fluoro-ATP production. Biochem Pharmacol. 1987 Sep 15; 36(18):2945-50. PMID: 3307790.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    74. Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism. Stem Cell Research and Therapy.
    75. SIRT2 deacetylates and inhibits the peroxidase activity of peroxiredoxin-1 to sensitize breast cancer cells to oxidant stress-inducing agents. Cancer Research. 76:5467-5478.
    76. Intracellular metabolism and action of an antitumor nucleoside, 2'-C- cyano-2'-deoxy-1-β-D-arabinofuranosylcytosine (CNDAC). Nucleosides and Nucleotides. 16:1037-1039.
    77. Erratum. Cell. 111:1055.
    78. Apoptosis in chronic lymphocytic leukemia. Cancer Bulletin. 46:130-135.
    79. Metabolic alterations and drug sensitivity of tyrosine kinase inhibitor resistant leukemia cells with a FLT3/ITD mutation. Cancer Letters. 377:149-157.
    80. Oxidative stress, cell proliferation, and apoptosis. 309-332.
    81. ACS Symposium Series. 639:265-278.
    82. Oxidative stress and drug resistance in cancer. 137-175.
    83. Models of reactive oxygen species in cancer. Drug Discovery Today: Disease Models. 4:67-73.
    84. Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with an antiangina drug perhexiline. Oncogene.
    85. Identification of NDUFAF1 in mediating K-Ras induced mitochondrial dysfunction by a proteomic screening approach. Oncotarget. 6:3947-3962.
    86. Superoxide dismutase. Expert Opinion on Therapeutic Targets. 5:697-710.
    87. Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression. International Journal of Oncology. 50:252-262.
    88. Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism. Oncotarget. 7:71378-71389.
    89. Correction to Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 [Molecular Cell 61, 520-534, (2016)]. Molecular Cell. 61:640.
    90. Cu/Pd-Catalyzed Cascade Reactions of Cyclic Diaryliodoniums and Alkynes - Access to Fluorenes with Conjugate Enynes/Dienes. European Journal of Organic Chemistry. 2016:1110-1118.
    91. Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress. Free Radical Biology and Medicine. 99:436-450.
    92. Cancer stem cells, metabolism, and therapeutic significance. Tumor Biology. 1-8.
    93. Gemcitabine. Nucleosides and Nucleotides. 16:1261-1270.
    94. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget. 6:21148-21158.
    95. Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression. Journal of Experimental and Clinical Cancer Research. 35.
    96. Chinese Journal of Cancer. 34.
    97. Synthesis of carbazoles via one-pot copper-catalyzed amine insertion into cyclic diphenyleneiodoniums as a strategy to generate a drug-like chemical library. Advanced Synthesis and Catalysis. 355:2172-2178.
    98. Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53. Mitochondrion. 31:33-39.
    99. N-Benzyldithiocarbamate Salts as Sulfur Sources to Access Tricyclic Thioheterocycles Mediated by Copper Species. Advanced Synthesis and Catalysis.
    100. Synthesis and biological evaluation of santacruzamate A and analogs as potential anticancer agents. RSC Advances. 5:1109-1112.
    101. MGMT in colorectal cancer. Tumor Biology. 1-14.
    102. Targeting mitochondria of cancer cells. 183-210.
    HUANG's Networks
    Click the
    buttons for more information and interactive visualizations!
    Concepts (450)
    Co-Authors (79)
    Similar People (60)
    Same Department Expand Description