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CHUN LI

TitleProfessor
InstitutionMD Anderson
DepartmentCancer Systems Imaging
Address1881 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zhou M, Zhao J, Tian M, Song S, Zhang R, Gupta S, Tan D, Shen H, Ferrari M, Li C. Radio-photothermal therapy mediated by a single compartment nanoplatform depletes tumor initiating cells and reduces lung metastasis in the orthotopic 4T1 breast tumor model. Nanoscale. 2015 Dec 14; 7(46):19438-47. PMID: 26376843.
      View in: PubMed
    2. Zhou M, Ku G, Pageon L, Li C. Theranostic probe for simultaneous in vivo photoacoustic imaging and confined photothermolysis by pulsed laser at 1064 nm in 4T1 breast cancer model. Nanoscale. 2014 Dec 21; 6(24):15228-35. PMID: 25379880; PMCID: PMC4389689.
    3. You J, Zhou J, Zhou M, Liu Y, Robertson JD, Liang D, Van Pelt C, Li C. Pharmacokinetics, clearance, and biosafety of polyethylene glycol-coated hollow gold nanospheres. Part Fibre Toxicol. 2014; 11:26. PMID: 24886070; PMCID: PMC4082425.
    4. You J, Zhang P, Hu F, Du Y, Yuan H, Zhu J, Wang Z, Zhou J, Li C. Near-infrared light-sensitive liposomes for the enhanced photothermal tumor treatment by the combination with chemotherapy. Pharm Res. 2014 Mar; 31(3):554-65. PMID: 24022681.
      View in: PubMed
    5. Li C. A targeted approach to cancer imaging and therapy. Nat Mater. 2014 Feb; 13(2):110-5. PMID: 24452345; PMCID: PMC4234179.
    6. Huang M, Xiong C, Lu W, Zhang R, Zhou M, Huang Q, Weinberg J, Li C. Dual-modality micro-positron emission tomography/computed tomography and near-infrared fluorescence imaging of EphB4 in orthotopic glioblastoma xenograft models. Mol Imaging Biol. 2014 Feb; 16(1):74-84. PMID: 23918654; PMCID: PMC3947091.
    7. Tian M, Lu W, Zhang R, Xiong C, Ensor J, Nazario J, Jackson J, Shaw C, Dixon KA, Miller J, Wright K, Li C, Gupta S. Tumor uptake of hollow gold nanospheres after intravenous and intra-arterial injection: PET/CT study in a rabbit VX2 liver cancer model. Mol Imaging Biol. 2013 Oct; 15(5):614-24. PMID: 23608932; PMCID: PMC4164961.
    8. Lee HJ, Liu Y, Zhao J, Zhou M, Bouchard RR, Mitcham T, Wallace M, Stafford RJ, Li C, Gupta S, Melancon MP. In vitro and in vivo mapping of drug release after laser ablation thermal therapy with doxorubicin-loaded hollow gold nanoshells using fluorescence and photoacoustic imaging. J Control Release. 2013 Nov 28; 172(1):152-8. PMID: 23920038; PMCID: PMC3853126.
    9. Zhu H, Zhao J, Lin X, Hong Y, Li C, Yang Z. Design, synthesis and evaluation of dual-modality glyco-nanoparticles for tumor imaging. Molecules. 2013; 18(6):6425-38. PMID: 23722731.
      View in: PubMed
    10. Zhang R, Huang M, Zhou M, Wen X, Huang Q, Li C. Annexin A5-functionalized nanoparticle for multimodal imaging of cell death. Mol Imaging. 2013 May; 12(3):182-90. PMID: 23490444; PMCID: PMC3893065.
    11. Zhao N, You J, Zeng Z, Li C, Zu Y. An ultra pH-sensitive and aptamer-equipped nanoscale drug-delivery system for selective killing of tumor cells. Small. 2013 Oct 25; 9(20):3477-84. PMID: 23609964.
      View in: PubMed
    12. You J, Wang Z, Du Y, Yuan H, Zhang P, Zhou J, Liu F, Li C, Hu F. Specific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheres. Biomaterials. 2013 Jun; 34(18):4510-9. PMID: 23510855; PMCID: PMC4107678.
    13. Song S, Xiong C, Lu W, Ku G, Huang G, Li C. Apoptosis imaging probe predicts early chemotherapy response in preclinical models: A comparative study with 18F-FDG PET. J Nucl Med. 2013 Jan; 54(1):104-10. PMID: 23283564.
      View in: PubMed
    14. Melancon MP, Stafford RJ, Li C. Challenges to effective cancer nanotheranostics. J Control Release. 2012 Dec 10; 164(2):177-82. PMID: 22906841; PMCID: PMC3504179.
    15. You J, Zhang R, Xiong C, Zhong M, Melancon M, Gupta S, Nick AM, Sood AK, Li C. Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res. 2012 Sep 15; 72(18):4777-86. PMID: 22865457.
      View in: PubMed
    16. Ku G, Zhou M, Song S, Huang Q, Hazle J, Li C. Copper sulfide nanoparticles as a new class of photoacoustic contrast agent for deep tissue imaging at 1064 nm. ACS Nano. 2012 Aug 28; 6(8):7489-96. PMID: 22812694; PMCID: PMC3429766.
    17. Lu W, Xiong C, Zhang R, Shi L, Huang M, Zhang G, Song S, Huang Q, Liu GY, Li C. Receptor-mediated transcytosis: a mechanism for active extravascular transport of nanoparticles in solid tumors. J Control Release. 2012 Aug 10; 161(3):959-66. PMID: 22617522; PMCID: PMC3412909.
    18. Zhang G, Zhang R, Melancon MP, Wong K, You J, Huang Q, Bankson J, Liang D, Li C. The degradation and clearance of Poly(N-hydroxypropyl-L-glutamine)-DTPA-Gd as a blood pool MRI contrast agent. Biomaterials. 2012 Jul; 33(21):5376-83. PMID: 22541356; PMCID: PMC3356511.
    19. Gupta S, Stafford RJ, Javadi S, Ozkan E, Ensor JE, Wright KC, Elliot AM, Jian Y, Serda RE, Dixon KA, Miller JJ, Klump S, Wallace MJ, Li C. Effects of Near-infrared Laser Irradiation of Biodegradable Microspheres Containing Hollow Gold Nanospheres and Paclitaxel Administered Intraarterially in a Rabbit Liver Tumor Model. J Vasc Interv Radiol. 2012 Apr; 23(4):553-61. PMID: 22341633; PMCID: PMC3863906.
    20. Shen H, You J, Zhang G, Ziemys A, Li Q, Bai L, Deng X, Erm DR, Liu X, Li C, Ferrari M. Cooperative, nanoparticle-enabled thermal therapy of breast cancer. Adv Healthc Mater. 2012 Jan 11; 1(1):84-9. PMID: 23184690; PMCID: PMC3842222.
    21. Cao Y, Marks JD, Huang Q, Rudnick SI, Xiong C, Hittelman WN, Wen X, Marks JW, Cheung LH, Boland K, Li C, Adams GP, Rosenblum MG. Single-chain antibody-based immunotoxins targeting Her2/neu: design optimization and impact of affinity on antitumor efficacy and off-target toxicity. Mol Cancer Ther. 2012 Jan; 11(1):143-53. PMID: 22090420.
      View in: PubMed
    22. You J, Zhang R, Zhang G, Zhong M, Liu Y, Van Pelt CS, Liang D, Wei W, Sood AK, Li C. Photothermal-chemotherapy with doxorubicin-loaded hollow gold nanospheres: A platform for near-infrared light-trigged drug release. J Control Release. 2012 Mar 10; 158(2):319-28. PMID: 22063003; PMCID: PMC3463239.
    23. Perin EC, Tian M, Marini FC, Silva GV, Zheng Y, Baimbridge F, Quan X, Fernandes MR, Gahremanpour A, Young D, Paolillo V, Mukhopadhyay U, Borne AT, Uthamanthil R, Brammer D, Jackson J, Decker WK, Najjar AM, Thomas MW, Volgin A, Rabinovich B, Soghomonyan S, Jeong HJ, Rios JM, Steiner D, Robinson S, Mawlawi O, Pan T, Stafford J, Kundra V, Li C, Alauddin MM, Willerson JT, Shpall E, Gelovani JG. Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. PLoS One. 2011; 6(9):e22949. PMID: 21912635; PMCID: PMC3164664.
    24. Lu W, Melancon MP, Xiong C, Huang Q, Elliott A, Song S, Zhang R, Flores LG, Gelovani JG, Wang LV, Ku G, Stafford RJ, Li C. Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma. Cancer Res. 2011 Oct 1; 71(19):6116-21. PMID: 21856744; PMCID: PMC3185126.
    25. Melancon MP, Zhou M, Li C. Cancer theranostics with near-infrared light-activatable multimodal nanoparticles. Acc Chem Res. 2011 Oct 18; 44(10):947-56. PMID: 21848277; PMCID: PMC3196765.
    26. Wen X, Lyu MA, Zhang R, Lu W, Huang Q, Liang D, Rosenblum MG, Li C. Biodistribution, pharmacokinetics, and nuclear imaging studies of 111In-labeled rGel/BLyS fusion toxin in SCID mice bearing B cell lymphoma. Mol Imaging Biol. 2011 Aug; 13(4):721-9. PMID: 20686856.
      View in: PubMed
    27. Melancon MP, Lu W, Zhong M, Zhou M, Liang G, Elliott AM, Hazle JD, Myers JN, Li C, Stafford RJ. Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer. Biomaterials. 2011 Oct; 32(30):7600-8. PMID: 21745689; PMCID: PMC3195359.
    28. Melancon MP, Elliott AM, Shetty A, Huang Q, Stafford RJ, Li C. Near-infrared light modulated photothermal effect increases vascular perfusion and enhances polymeric drug delivery. J Control Release. 2011 Dec 10; 156(2):265-72. PMID: 21763373; PMCID: PMC3203335.
    29. Zhang R, Xiong C, Huang M, Zhou M, Huang Q, Wen X, Liang D, Li C. Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts. Biomaterials. 2011 Sep; 32(25):5872-9. PMID: 21612822; PMCID: PMC3110559.
    30. Zhang R, Lu W, Wen X, Huang M, Zhou M, Liang D, Li C. Annexin A5-conjugated polymeric micelles for dual SPECT and optical detection of apoptosis. J Nucl Med. 2011 Jun; 52(6):958-64. PMID: 21571801; PMCID: PMC3463236.
    31. Song S, Xiong C, Zhou M, Lu W, Huang Q, Ku G, Zhao J, Flores LG, Ni Y, Li C. Small-animal PET of tumor damage induced by photothermal ablation with 64Cu-bis-DOTA-hypericin. J Nucl Med. 2011 May; 52(5):792-9. PMID: 21498539.
      View in: PubMed
    32. Xiong C, Brewer K, Song S, Zhang R, Lu W, Wen X, Li C. Peptide-based imaging agents targeting phosphatidylserine for the detection of apoptosis. J Med Chem. 2011 Mar 24; 54(6):1825-35. PMID: 21348464.
      View in: PubMed
    33. Melancon MP, Elliott A, Ji X, Shetty A, Yang Z, Tian M, Taylor B, Stafford RJ, Li C. Theranostics with multifunctional magnetic gold nanoshells: photothermal therapy and t2* magnetic resonance imaging. Invest Radiol. 2011 Feb; 46(2):132-40. PMID: 21150791; PMCID: PMC3435880.
    34. Melancon MP, Li C. Multifunctional synthetic poly(L-glutamic acid)-based cancer therapeutic and imaging agents. Mol Imaging. 2011 Feb; 10(1):28-42. PMID: 21303613; PMCID: PMC3435883.
    35. Xiong C, Huang M, Zhang R, Song S, Lu W, Flores L, Gelovani J, Li C. In vivo small-animal PET/CT of EphB4 receptors using 64Cu-labeled peptide. J Nucl Med. 2011 Feb; 52(2):241-8. PMID: 21233177.
      View in: PubMed
    36. Tian M, Wen X, Jackson EF, Ng C, Uthamanthil R, Liang D, Gelovani JG, Li C. Pharmacokinetics and magnetic resonance imaging of biodegradable macromolecular blood-pool contrast agent PG-Gd in non-human primates: a pilot study. Contrast Media Mol Imaging. 2011 Jul-Aug; 6(4):289-97. PMID: 21861289.
      View in: PubMed
    37. Zhou M, Zhang R, Huang M, Lu W, Song S, Melancon MP, Tian M, Liang D, Li C. A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy. J Am Chem Soc. 2010 Nov 3; 132(43):15351-8. PMID: 20942456; PMCID: PMC2966020.
    38. Fang C, Veiseh O, Kievit F, Bhattarai N, Wang F, Stephen Z, Li C, Lee D, Ellenbogen RG, Zhang M. Functionalization of iron oxide magnetic nanoparticles with targeting ligands: their physicochemical properties and in vivo behavior. Nanomedicine (Lond). 2010 Nov; 5(9):1357-69. PMID: 21128719.
      View in: PubMed
    39. Li Y, Lu W, Huang Q, Huang M, Li C, Chen W. Copper sulfide nanoparticles for photothermal ablation of tumor cells. Nanomedicine (Lond). 2010 Oct; 5(8):1161-71. PMID: 21039194.
      View in: PubMed
    40. Belousova N, Mikheeva G, Xiong C, Soghomonian S, Young D, Le Roux L, Naff K, Bidaut L, Wei W, Li C, Gelovani J, Krasnykh V. Development of a targeted gene vector platform based on simian adenovirus serotype 24. J Virol. 2010 Oct; 84(19):10087-101. PMID: 20631120; PMCID: PMC2937776.
    41. You J, Shao R, Wei X, Gupta S, Li C. Near-infrared light triggers release of Paclitaxel from biodegradable microspheres: photothermal effect and enhanced antitumor activity. Small. 2010 May 7; 6(9):1022-31. PMID: 20394071; PMCID: PMC3435885.
    42. Lu W, Zhang G, Zhang R, Flores LG, Huang Q, Gelovani JG, Li C. Tumor site-specific silencing of NF-kappaB p65 by targeted hollow gold nanosphere-mediated photothermal transfection. Cancer Res. 2010 Apr 15; 70(8):3177-88. PMID: 20388791.
      View in: PubMed
    43. You J, Zhang G, Li C. Exceptionally high payload of doxorubicin in hollow gold nanospheres for near-infrared light-triggered drug release. ACS Nano. 2010 Feb 23; 4(2):1033-41. PMID: 20121065; PMCID: PMC2835401.
    44. Lu W, Huang Q, Ku G, Wen X, Zhou M, Guzatov D, Brecht P, Su R, Oraevsky A, Wang LV, Li C. Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres. Biomaterials. 2010 Mar; 31(9):2617-26. PMID: 20036000; PMCID: PMC2813997.
    45. Xiong C, Lu W, Zhang R, Tian M, Tong W, Gelovani J, Li C. Cell-permeable [99mTc(CO3)]-labeled fluorogenic caspase 3 substrate for dual-modality detection of apoptosis. Chemistry. 2009 Sep 14; 15(36):8979-84. PMID: 19637160.
      View in: PubMed
    46. Cao W, Bover L, Cho M, Wen X, Hanabuchi S, Bao M, Rosen DB, Wang YH, Shaw JL, Du Q, Li C, Arai N, Yao Z, Lanier LL, Liu YJ. Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction. J Exp Med. 2009 Jul 6; 206(7):1603-14. PMID: 19564354; PMCID: PMC2715090.
    47. Wang W, Shao R, Wu Q, Ke S, McMurray J, Lang FF, Charnsangavej C, Gelovani JG, Li C. Targeting gelatinases with a near-infrared fluorescent cyclic His-Try-Gly-Phe peptide. Mol Imaging Biol. 2009 Nov-Dec; 11(6):424-33. PMID: 19424760; PMCID: PMC3435882.
    48. Yang Z, Kontoyiannis DP, Wen X, Xiong C, Zhang R, Albert ND, Li C. Gamma scintigraphy imaging of murine invasive pulmonary aspergillosis with a (111)In-labeled cyclic peptide. Nucl Med Biol. 2009 Apr; 36(3):259-66. PMID: 19324271.
      View in: PubMed
    49. Yang Z, Leon J, Martin M, Harder JW, Zhang R, Liang D, Lu W, Tian M, Gelovani JG, Qiao A, Li C. Pharmacokinetics and biodistribution of near-infrared fluorescence polymeric nanoparticles. Nanotechnology. 2009 Apr 22; 20(16):165101. PMID: 19420561; PMCID: PMC2745816.
    50. Thapa P, Zhang G, Xia C, Gelbard A, Overwijk WW, Liu C, Hwu P, Chang DZ, Courtney A, Sastry JK, Wang PG, Li C, Zhou D. Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy. Vaccine. 2009 May 26; 27(25-26):3484-8. PMID: 19200815.
      View in: PubMed
    51. Lu W, Xiong C, Zhang G, Huang Q, Zhang R, Zhang JZ, Li C. Targeted photothermal ablation of murine melanomas with melanocyte-stimulating hormone analog-conjugated hollow gold nanospheres. Clin Cancer Res. 2009 Feb 1; 15(3):876-86. PMID: 19188158; PMCID: PMC2727065.
    52. Zhang G, Yang Z, Lu W, Zhang R, Huang Q, Tian M, Li L, Liang D, Li C. Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials. 2009 Apr; 30(10):1928-36. PMID: 19131103; PMCID: PMC2745599.
    53. Xiong C, Yang Z, Zhang R, Tong W, Gelovani J, Li C. 99mTc-labeled Ac-DEVD peptides as a substrate for measuring caspase activity. Adv Exp Med Biol. 2009; 611:455-6. PMID: 19400264.
      View in: PubMed
    54. Melancon MP, Lu W, Yang Z, Zhang R, Cheng Z, Elliot AM, Stafford J, Olson T, Zhang JZ, Li C. In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy. Mol Cancer Ther. 2008 Jun; 7(6):1730-9. PMID: 18566244; PMCID: PMC2727060.
    55. Frank SJ, Stafford RJ, Bankson JA, Li C, Swanson DA, Kudchadker RJ, Martirosyan KS. A novel MRI marker for prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2008 May 1; 71(1):5-8. PMID: 18406882.
      View in: PubMed
    56. Li C, Wallace S. Polymer-drug conjugates: recent development in clinical oncology. Adv Drug Deliv Rev. 2008 May 22; 60(8):886-98. PMID: 18374448; PMCID: PMC2432086.
    57. Zhang G, Zhang R, Wen X, Li L, Li C. Micelles based on biodegradable poly(L-glutamic acid)-b-polylactide with paramagnetic Gd ions chelated to the shell layer as a potential nanoscale MRI-visible delivery system. Biomacromolecules. 2008 Jan; 9(1):36-42. PMID: 18047289.
      View in: PubMed
    58. Shao R, Xiong C, Wen X, Gelovani JG, Li C. Targeting phosphatidylserine on apoptotic cells with phages and peptides selected from a bacteriophage display library. Mol Imaging. 2007 Nov-Dec; 6(6):417-26. PMID: 18053412.
      View in: PubMed
    59. Yang Z, Zheng S, Harrison WJ, Harder J, Wen X, Gelovani JG, Qiao A, Li C. Long-circulating near-infrared fluorescence core-cross-linked polymeric micelles: synthesis, characterization, and dual nuclear/optical imaging. Biomacromolecules. 2007 Nov; 8(11):3422-8. PMID: 17958440; PMCID: PMC2542943.
    60. Zou C, Brewer M, Cao X, Zang R, Lin J, Deng Y, Li C. Antitumor activity of 4-(N-hydroxyphenyl)retinamide conjugated with poly(L-glutamic acid) against ovarian cancer xenografts. Gynecol Oncol. 2007 Dec; 107(3):441-9. PMID: 17854871.
      View in: PubMed
    61. Zhu G, Cao X, Chang JY, Milas L, Wallace S, Li C. Polymeric retinoid prodrug PG-4HPR enhances the radiation response of lung cancer. Oncol Rep. 2007 Sep; 18(3):645-51. PMID: 17671714.
      View in: PubMed
    62. Melancon MP, Wang Y, Wen X, Bankson JA, Stephens LC, Jasser S, Gelovani JG, Myers JN, Li C. Development of a macromolecular dual-modality MR-optical imaging for sentinel lymph node mapping. Invest Radiol. 2007 Aug; 42(8):569-78. PMID: 17620940; PMCID: PMC2746745.
    63. Jackson EF, Esparza-Coss E, Wen X, Ng CS, Daniel SL, Price RE, Rivera B, Charnsangavej C, Gelovani JG, Li C. Magnetic resonance imaging of therapy-induced necrosis using gadolinium-chelated polyglutamic acids. Int J Radiat Oncol Biol Phys. 2007 Jul 1; 68(3):830-8. PMID: 17379450; PMCID: PMC1997292.
    64. Melancon MP, Wang W, Wang Y, Shao R, Ji X, Gelovani JG, Li C. A novel method for imaging in vivo degradation of poly(L-glutamic acid), a biodegradable drug carrier. Pharm Res. 2007 Jun; 24(6):1217-24. PMID: 17377742; PMCID: PMC2746742.
    65. Oh SH, Lee OH, Schroeder CP, Oh YW, Ke S, Cha HJ, Park RW, Onn A, Herbst RS, Li C, Lee HY. Antimetastatic activity of insulin-like growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor-independent urokinase-type plasminogen activator inhibition. Mol Cancer Ther. 2006 Nov; 5(11):2685-95. PMID: 17121915.
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    66. Liu Y, Zhang W, Cheung LH, Niu T, Wu Q, Li C, Van Pelt CS, Rosenblum MG. The antimelanoma immunocytokine scFvMEL/TNF shows reduced toxicity and potent antitumor activity against human tumor xenografts. Neoplasia. 2006 May; 8(5):384-93. PMID: 16790087; PMCID: PMC1592449.
    67. Li C, Wang W, Wu Q, Ke S, Houston J, Sevick-Muraca E, Dong L, Chow D, Charnsangavej C, Gelovani JG. Dual optical and nuclear imaging in human melanoma xenografts using a single targeted imaging probe. Nucl Med Biol. 2006 Apr; 33(3):349-58. PMID: 16631083.
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    68. Wang W, McMurray JS, Wu Q, Campbell ML, Li C. Convenient solid-phase synthesis of diethylenetriaminepenta-acetic acid (DTPA)- conjugated cyclic RGD peptide analogues. Cancer Biother Radiopharm. 2005 Oct; 20(5):547-56. PMID: 16248770.
      View in: PubMed
    69. Houston JP, Ke S, Wang W, Li C, Sevick-Muraca EM. Quality analysis of in vivo near-infrared fluorescence and conventional gamma images acquired using a dual-labeled tumor-targeting probe. J Biomed Opt. 2005 Sep-Oct; 10(5):054010. PMID: 16292970.
      View in: PubMed
    70. Hwang K, Houston JP, Rasmussen JC, Joshi A, Ke S, Li C, Sevick-Muraca EM. Improved excitation light rejection enhances small-animal fluorescent optical imaging. Mol Imaging. 2005 Jul-Sep; 4(3):194-204. PMID: 16194451.
      View in: PubMed
    71. Gurfinkel M, Ke S, Wang W, Li C, Sevick-Muraca EM. Quantifying molecular specificity of alphavbeta3 integrin-targeted optical contrast agents with dynamic optical imaging. J Biomed Opt. 2005 May-Jun; 10(3):034019. PMID: 16229663.
      View in: PubMed
    72. Wang W, Wu Q, Pasuelo M, McMurray JS, Li C. Probing for integrin alpha v beta3 binding of RGD peptides using fluorescence polarization. Bioconjug Chem. 2005 May-Jun; 16(3):729-34. PMID: 15898744.
      View in: PubMed
    73. Kwon S, Ke S, Houston JP, Wang W, Wu Q, Li C, Sevick-Muraca EM. Imaging dose-dependent pharmacokinetics of an RGD-fluorescent dye conjugate targeted to alpha v beta 3 receptor expressed in Kaposi's sarcoma. Mol Imaging. 2005 Apr-Jun; 4(2):75-87. PMID: 16105505.
      View in: PubMed
    74. Wen X, Jackson EF, Price RE, Kim EE, Wu Q, Wallace S, Charnsangavej C, Gelovani JG, Li C. Synthesis and characterization of poly(L-glutamic acid) gadolinium chelate: a new biodegradable MRI contrast agent. Bioconjug Chem. 2004 Nov-Dec; 15(6):1408-15. PMID: 15546209.
      View in: PubMed
    75. Wen X, Cao X, Pasuelo MJ, Wendt R, Li C. Polymeric radiotracers in nuclear imaging. Curr Drug Deliv. 2004 Oct; 1(4):377-84. PMID: 16305399.
      View in: PubMed
    76. Wang W, Ke S, Wu Q, Charnsangavej C, Gurfinkel M, Gelovani JG, Abbruzzese JL, Sevick-Muraca EM, Li C. Near-infrared optical imaging of integrin alphavbeta3 in human tumor xenografts. Mol Imaging. 2004 Oct; 3(4):343-51. PMID: 15802051.
      View in: PubMed
    77. Belhocine TZ, Tait JF, Vanderheyden JL, Li C, Blankenberg FG. Nuclear medicine in the era of genomics and proteomics: lessons from annexin V. J Proteome Res. 2004 May-Jun; 3(3):345-9. PMID: 15253415.
      View in: PubMed
    78. Hossain A, Li C, Saunders GF. Generation of two distinct functional isoforms of dosage-sensitive sex reversal-adrenal hypoplasia congenita-critical region on the X chromosome gene 1 (DAX-1) by alternative splicing. Mol Endocrinol. 2004 Jun; 18(6):1428-37. PMID: 15044589.
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    79. Belhocine T, Steinmetz N, Li C, Green A, Blankenberg FG. The imaging of apoptosis with the radiolabeled annexin V: optimal timing for clinical feasibility. Technol Cancer Res Treat. 2004 Feb; 3(1):23-32. PMID: 14750890.
      View in: PubMed
    80. Tansey W, Ke S, Cao XY, Pasuelo MJ, Wallace S, Li C. Synthesis and characterization of branched poly(L-glutamic acid) as a biodegradable drug carrier. J Control Release. 2004 Jan 8; 94(1):39-51. PMID: 14684270.
      View in: PubMed
    81. Ke S, Wen X, Wu QP, Wallace S, Charnsangavej C, Stachowiak AM, Stephens CL, Abbruzzese JL, Podoloff DA, Li C. Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin V. J Nucl Med. 2004 Jan; 45(1):108-15. PMID: 14734682.
      View in: PubMed
    82. Ke S, Wen X, Gurfinkel M, Charnsangavej C, Wallace S, Sevick-Muraca EM, Li C. Near-infrared optical imaging of epidermal growth factor receptor in breast cancer xenografts. Cancer Res. 2003 Nov 15; 63(22):7870-5. PMID: 14633715.
      View in: PubMed
    83. Wen X, Wu QP, Ke S, Wallace S, Charnsangavej C, Huang P, Liang D, Chow D, Li C. Improved radiolabeling of PEGylated protein: PEGylated annexin V for noninvasive imaging of tumor apoptosis. Cancer Biother Radiopharm. 2003 Oct; 18(5):819-27. PMID: 14629830.
      View in: PubMed
    84. Vega J, Ke S, Fan Z, Wallace S, Charsangavej C, Li C. Targeting doxorubicin to epidermal growth factor receptors by site-specific conjugation of C225 to poly(L-glutamic acid) through a polyethylene glycol spacer. Pharm Res. 2003 May; 20(5):826-32. PMID: 12751641.
      View in: PubMed
    85. Milas L, Mason KA, Hunter N, Li C, Wallace S. Poly(L-glutamic acid)-paclitaxel conjugate is a potent enhancer of tumor radiocurability. Int J Radiat Oncol Biol Phys. 2003 Mar 1; 55(3):707-12. PMID: 12573758.
      View in: PubMed
    86. Le XF, Hittelman WN, Liu J, McWatters A, Li C, Mills GB, Bast RC. Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis. Oncogene. 2003 Jan 30; 22(4):484-97. PMID: 12555062.
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    87. Gurfinkel M, Ke S, Wen X, Li C, Sevick-Muraca EM. Near-infrared fluorescence optical imaging and tomography. Dis Markers. 2003-2004; 19(2-3):107-21. PMID: 15096708; PMCID: PMC3851384.
    88. Li C. Poly(L-glutamic acid)--anticancer drug conjugates. Adv Drug Deliv Rev. 2002 Sep 13; 54(5):695-713. PMID: 12204599.
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    89. Auzenne E, Donato NJ, Li C, Leroux E, Price RE, Farquhar D, Klostergaard J. Superior therapeutic profile of poly-L-glutamic acid-paclitaxel copolymer compared with taxol in xenogeneic compartmental models of human ovarian carcinoma. Clin Cancer Res. 2002 Feb; 8(2):573-81. PMID: 11839679.
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    90. Wen X, Wu QP, Ke S, Ellis L, Charnsangavej C, Delpassand AS, Wallace S, Li C. Conjugation with (111)In-DTPA-poly(ethylene glycol) improves imaging of anti-EGF receptor antibody C225. J Nucl Med. 2001 Oct; 42(10):1530-7. PMID: 11585869.
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    91. Ke S, Milas L, Charnsangavej C, Wallace S, Li C. Potentiation of radioresponse by polymer-drug conjugates. J Control Release. 2001 Jul 6; 74(1-3):237-42. PMID: 11489500.
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    92. Wen X, Wu QP, Lu Y, Fan Z, Charnsangavej C, Wallace S, Chow D, Li C. Poly(ethylene glycol)-conjugated anti-EGF receptor antibody C225 with radiometal chelator attached to the termini of polymer chains. Bioconjug Chem. 2001 Jul-Aug; 12(4):545-53. PMID: 11459459.
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    93. Zou Y, Wu QP, Tansey W, Chow D, Hung MC, Charnsangavej C, Wallace S, Li C. Effectiveness of water soluble poly(L-glutamic acid)-camptothecin conjugate against resistant human lung cancer xenografted in nude mice. Int J Oncol. 2001 Feb; 18(2):331-6. PMID: 11172600.
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    94. Li C, Ke S, Wu QP, Tansey W, Hunter N, Buchmiller LM, Milas L, Charnsangavej C, Wallace S. Potentiation of ovarian OCa-1 tumor radioresponse by poly (L-glutamic acid)-paclitaxel conjugate. Int J Radiat Oncol Biol Phys. 2000 Nov 1; 48(4):1119-26. PMID: 11072171.
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    95. Li C, Ke S, Wu QP, Tansey W, Hunter N, Buchmiller LM, Milas L, Charnsangavej C, Wallace S. Tumor irradiation enhances the tumor-specific distribution of poly(L-glutamic acid)-conjugated paclitaxel and its antitumor efficacy. Clin Cancer Res. 2000 Jul; 6(7):2829-34. PMID: 10914731.
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    96. Wallace S, Kan Z, Li C. Hepatic chemoembolization: clinical and experimental correlation. Acta Gastroenterol Belg. 2000 Apr-Jun; 63(2):169-73. PMID: 10925454.
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    97. Li C, Newman RA, Wu QP, Ke S, Chen W, Hutto T, Kan Z, Brannan MD, Charnsangavej C, Wallace S. Biodistribution of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in mice with ovarian OCa-1 tumor. Cancer Chemother Pharmacol. 2000; 46(5):416-22. PMID: 11127947.
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    98. Singer JW, De Vries P, Bhatt R, Tulinsky J, Klein P, Li C, Milas L, Lewis RA, Wallace S. Conjugation of camptothecins to poly-(L-glutamic acid). Ann N Y Acad Sci. 2000; 922:136-50. PMID: 11193889.
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    99. Oldham EA, Li C, Ke S, Wallace S, Huang P. Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells. Int J Oncol. 2000 Jan; 16(1):125-32. PMID: 10601557.
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    100. Inoue T, Li C, Yang DJ, Higuchi T, Oriuchi N, Yu D, Milas L, Hunter N, Wallace S, Kim EE, Podoloff DA. Evaluation of In-111 DTPA-paclitaxel scintigraphy to predict response on murine tumors to paclitaxel. Ann Nucl Med. 1999 Jun; 13(3):169-74. PMID: 10435377.
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    101. Li C, Price JE, Milas L, Hunter NR, Ke S, Yu DF, Charnsangavej C, Wallace S. Antitumor activity of poly(L-glutamic acid)-paclitaxel on syngeneic and xenografted tumors. Clin Cancer Res. 1999 Apr; 5(4):891-7. PMID: 10213226.
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    102. Multani AS, Li C, Ozen M, Imam AS, Wallace S, Pathak S. Cell-killing by paclitaxel in a metastatic murine melanoma cell line is mediated by extensive telomere erosion with no decrease in telomerase activity. Oncol Rep. 1999 Jan-Feb; 6(1):39-44. PMID: 9864398.
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    103. Li C, Yu DF, Newman RA, Cabral F, Stephens LC, Hunter N, Milas L, Wallace S. Complete regression of well-established tumors using a novel water-soluble poly(L-glutamic acid)-paclitaxel conjugate. Cancer Res. 1998 Jun 1; 58(11):2404-9. PMID: 9622081.
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    104. Multani AS, Li C, Ozen M, Yadav M, Yu DF, Wallace S, Pathak S. Paclitaxel and water-soluble poly (L-glutamic acid)-paclitaxel, induce direct chromosomal abnormalities and cell death in a murine metastatic melanoma cell line. Anticancer Res. 1997 Nov-Dec; 17(6D):4269-74. PMID: 9494519.
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    105. Li C, Yu DF, Inoue T, Yang DJ, Tansey W, Liu CW, Milas L, Hunter NR, Kim EE, Wallace S. Synthesis, biodistribution and imaging properties of indium-111-DTPA-paclitaxel in mice bearing mammary tumors. J Nucl Med. 1997 Jul; 38(7):1042-7. PMID: 9225788.
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    106. Li C, Yu D, Inoue T, Yang DJ, Milas L, Hunter NR, Kim EE, Wallace S. Synthesis and evaluation of water-soluble polyethylene glycol-paclitaxel conjugate as a paclitaxel prodrug. Anticancer Drugs. 1996 Aug; 7(6):642-8. PMID: 8913432.
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    107. Li C, McCuskey P, Yang DJ, Kan Z, Wallace S. Development of biodegradable ioxilan carbonate particles for contrast enhancement of the liver in computed tomography scanning: toxicity assessment. Acad Radiol. 1996 Aug; 3 Suppl 2:S227-8. PMID: 8796568.
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    108. Li C, Yu D, Kan Z, Yang DJ, Tansey W, Kuang LR, Wallace S. Biodistribution of cyclic carbonate of ioxilan: a radiopaque particulate macrophage imaging agent. Acad Radiol. 1996 Jun; 3(6):500-6. PMID: 8796708.
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    109. Kim CG, Yang DJ, Kim EE, Cherif A, Kuang LR, Li C, Tansey W, Liu CW, Li SC, Wallace S, Podoloff DA. Assessment of tumor cell proliferation using [18F]fluorodeoxyadenosine and[18F]fluoroethyluracil. J Pharm Sci. 1996 Mar; 85(3):339-44. PMID: 8699341.
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    110. Yang DJ, Wallace S, Cherif A, Li C, Gretzer MB, Kim EE, Podoloff DA. Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia. Radiology. 1995 Mar; 194(3):795-800. PMID: 7862981.
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    111. Li C, Yang DJ, Nikiforow S, Tansey W, Kuang LR, Wright KC, Wallace S. Formation and characterization of cisplatin-loaded poly(benzyl l-glutamate) microspheres for chemoembolization. Pharm Res. 1994 Dec; 11(12):1792-9. PMID: 7534920.
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    112. Li C, Kan Z, Yang DJ, Kuang LR, Liu CW, Wright KC, Wallace S. Preparation, characterization, and evaluation of ioxilan carbonate particles for computed tomography contrast enhancement of liver. Invest Radiol. 1994 Nov; 29(11):1006-13. PMID: 7890508.
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    113. Li C, McCuskey P, Kan Z, Yang DJ, Wright KC, Wallace S. In vivo and electron microscopic studies of rat liver after intravenous injection of polyamino acid microspheres. J Biomed Mater Res. 1994 Aug; 28(8):881-90. PMID: 7527046.
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    114. Yang DJ, Kuang LR, Li C, Kan Z, Wallace S. Computed tomographic liver enhancement with poly(d,1-lactide)-microencapsulated contrast media. Invest Radiol. 1994 Jun; 29 Suppl 2:S267-70. PMID: 7928253.
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    115. Yang DJ, Li C, Nikiforow S, Gretzer MB, Kuang LR, Lopez MS, Vargas K, Wallace S. Diagnostic and therapeutic potential of poly(benzyl L-glutamate). J Pharm Sci. 1994 Mar; 83(3):328-31. PMID: 7515964.
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    116. Yang DJ, Li C, Kuang LR, Price JE, Buzdar AU, Tansey W, Cherif A, Gretzer M, Kim EE, Wallace S. Imaging, biodistribution and therapy potential of halogenated tamoxifen analogues. Life Sci. 1994; 55(1):53-67. PMID: 8015349.
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    117. Silver FH, Marks M, Kato YP, Li C, Pulapura S, Kohn J. Tissue compatibility of tyrosine-derived polycarbonates and polyiminocarbonates: an initial evaluation. J Long Term Eff Med Implants. 1992; 1(4):329-46. PMID: 10171118.
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    118. Pulapura S, Li C, Kohn J. Structure-property relationships for the design of polyiminocarbonates. Biomaterials. 1990 Nov; 11(9):666-78. PMID: 2090301.
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    119. Erythropoietin Stimulates Tumor Growth via EphB4. Cancer Cell. 28:610-622.
    120. Cell-permeable [99mTc(CO3)]-labeled fluorogenic caspase 3 substrate for dual-modality detection of apoptosis. Chemistry - A European Journal. 15:8979-8984.
    121. Single agent nanoparticle for radiotherapy and radio-photothermal therapy in anaplastic thyroid cancer. Biomaterials. 57:41-49.
    122. Combined photoacoustic and molecular fluorescence imaging in vivo. 190-192.
    123. N,N-Diethylfluoromethyltamoxifen. European Journal of Medicinal Chemistry. 27:919-924.
    124. CuS Nanodots with Ultrahigh Efficient Renal Clearance for Positron Emission Tomography Imaging and Image-Guided Photothermal Therapy. ACS Nano. 9:7085-7096.
    125. Design and radio-synthesis of somatostatin receptors targeted 68Ga-DOTA-Benereotide for non-invasive PET imaging. Journal of Radioanalytical and Nuclear Chemistry. 307:1069-1075.
    126. Synthesis of poly(iminocarbonates). Macromolecules. 22:2029-2036.
    127. Nanoprobe for optical molecular imaging. 343-344.
    128. Biodistribution and hepatic detection potential using microencapsulated contrast media. Proceedings of the Controlled Release Society. 188-189.
    129. Structural and magnetic properties of gold and silica doubly coated γ-Fe2O3 nanoparticles. Journal of Physical Chemistry C. 111:18512-18519.
    130. Antitumor Efficacy of Irreversible Electroporation and Doxorubicin-Loaded Polymeric Micelles. ACS Macro Letters. 4:1081-1084.
    131. Modeling laser thermal therapy output for nanoshell heating using a natural coordinate system.
    132. Image-guided photonic energy deposition for cancer ablation and drug delivery. Current Medical Imaging Reviews. 8:267-277.
    133. LANTCET.
    134. Macromolecular backbone rearrangements. A new approach to the synthesis of N-phenyl-substituted polyurethanes. Macromolecules. 24:2302-2308.
    135. Precision nanomedicine using dual PET and MR temperature imaging-guided photothermal therapy. Journal of Nuclear Medicine. 57:1778-1783.
    136. Theranostic CuS nanoparticles targeting folate receptors for PET image-guided photothermal therapy. Journal of Materials Chemistry B. 3:8939-8948.
    137. In vivo pharmacokinetic analysis for fluorescently labeled RGD peptide targeted to the α vβ 3 integrin in Kaposi's sarcoma . 263-269.
    138. Development of a new particulate contrast media as macrophage imaging agent. Proceedings of the Controlled Release Society. 192-193.
    139. Dual-modal tumor imaging via long-circulating biodegradable core-cross-linked polymeric micelles. ACS Macro Letters. 1:150-153.
    140. Multifunctional, multimodality cancer imaging with water-soluble synthetic polymer nanoparticles. 171-195.
    141. In vivo fluorescence imaging of cyanine derivative modified with epidermal growth factor, EGF-Cy5.5, in a murine model of carcinogenesis. 108-116.
    142. 64CuS-labeled nanoparticles. Contrast Media and Molecular Imaging.
    143. Synthetic Poly(L-Glutamic Acid)-conjugated CpG Exhibits Antitumor Efficacy with Increased Retention in Tumor and Draining Lymph Nodes after Intratumoral Injection in a Mouse Model of Melanoma. Journal of Immunotherapy. 40:11-20.
    144. Radio-photothermal therapy mediated by a single compartment nanoplatform depletes tumor initiating cells and reduces lung metastasis in the orthotopic 4T1 breast tumor model. Nanoscale. 7:19438-19447.
    145. Polyamino acid microspheres. International Journal of Pharmaceutics. 94:143-152.
    146. Dual-modality imaging in vivo with an NIR and gamma emitter using an intensified CCD camera and a conventional gamma camera. 10-15.
    147. Nanotechnology. Clinical Cancer Research. 21:3121-3130.
    148. Preparation and characterization of cisplatin-loaded PBLG microspheres for chemoembolization. Proceedings of the Controlled Release Society. 507-508.
    149. Nanoparticles for photoacoustic imaging of vasculature. 337-356.
    150. Simultaneous molecular and hypoxia imaging of brain tumors in vivo using spectroscopic photoacoustic tomography. Proceedings of the IEEE. 96:481-489.
    151. Bifunctional Gold Nanoshells with a Superparamagnetic Iron Oxide-Silica Core Suitable for Both MR Imaging and Photothermal Therapy. Journal of Physical Chemistry C. 111:6245-6251.
    152. Theranostic Applications of Gold Core-Shell Structured Nanoparticles. 683-708.
    153. Interventional nanotheranostics of pancreatic ductal adenocarcinoma. Theranostics. 6:1393-1402.
    154. Gold-based magneto/optical nanostructures. MRS Bulletin. 34:415-421.
    155. Copper-Based Nanomaterials for Cancer Imaging and Therapy. Bioconjugate Chemistry. 27:1188-1199.
    156. Photoacoustic tomography and molecular fluorescence imaging. 107-110.
    157. The influence of improved interference filter performance for molecular imaging using frequency domain photon migration measurements. 503-512.
    158. Hepatocellular carcinoma. Radiology. 281:427-435.
    159. Synthetic nanoparticles for delivery of radioisotopes and radiosensitizers in cancer therapy. Cancer Nanotechnology. 7.
    160. Photoacoustic molecular imaging of small animals in vivo.
    161. Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43. Oncotarget. 7:53414-53429.
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