MICHAEL KROLL

TitleProfessor
InstitutionMD Anderson
DepartmentPulmonary Medicine
Address1400 Pressler St
Houston TX 77030-4008
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    F32HL007608     (KROLL, MICHAEL H)Nov 1, 1987
    NIH
    CONTROL OF PLATELET SIGNAL TRANSDUCTION
    Role: Principal Investigator

    K08HL002311     (KROLL, MICHAEL H)Apr 1, 1989 - Mar 31, 1994
    NIH
    MECHANISMS ON VON WILLEBRAND FACTOR-INDUCED PLATELET ACT
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kroll MH, Rojas-Hernandez C, Yee C. Hematologic complications of immune checkpoint inhibitors. Blood. 2022 Jun 23; 139(25):3594-3604. PMID: 34610113.
      Citations:    Fields:    
    2. Hill A, Elakkad A, Kuban J, Sabir S, Odisio B, Huang SY, Mahvash A, Miller E, Kroll MH, Overman M, Tam AL, Gupta S, Sheth RA. Durability of partial splenic artery embolization on platelet counts for cancer patients with hypersplenism-related thrombocytopenia. Abdom Radiol (NY). 2020 09; 45(9):2886-2894. PMID: 32314004.
      Citations: 2     Fields:    Translation:Humans
    3. Agha AM, Gill C, Balanescu DV, Donisan T, Palaskas N, Lopez-Mattei J, Hassan S, Kim PY, Charitakis K, Cilingiroglu M, Oo TH, Kroll M, Durand JB, Hirsch-Ginsberg C, Marmagkiolis K, Iliescu C. Identifying Hemostatic Thresholds in Cancer Patients Undergoing Coronary Angiography Based on Platelet Count and Thromboelastography. Front Cardiovasc Med. 2020; 7:9. PMID: 32118047.
      Citations: 2     
    4. Kroll MH. The AHR: adaptive evolution or one-off? Blood. 2019 12 26; 134(26):2337-2338. PMID: 31877215.
      Citations: 1     Fields:    Translation:Animals
    5. Chamoun K, Loghavi S, Pemmaraju N, Konopleva M, Kroll M, Nguyen-Cao M, Hornbaker M, DiNardo CD, Kadia T, Jorgensen J, Andreeff M, Hu S, Benton CB. Early detection of transformation to BPDCN in a patient with MDS. Exp Hematol Oncol. 2018; 7:26. PMID: 30323983.
      Citations: 4     
    6. Chen LS, Bose P, Cruz ND, Jiang Y, Wu Q, Thompson PA, Feng S, Kroll MH, Qiao W, Huang X, Jain N, Wierda WG, Keating MJ, Gandhi V. A pilot study of lower doses of ibrutinib in patients with chronic lymphocytic leukemia. Blood. 2018 11 22; 132(21):2249-2259. PMID: 30254130.
      Citations: 26     Fields:    Translation:HumansCellsCTClinical Trials
    7. Huang SY, Odisio BC, Sabir SH, Ensor JE, Niekamp AS, Huynh TT, Kroll M, Gupta S. Development of a predictive model for 6 month survival in patients with venous thromboembolism and solid malignancy requiring IVC filter placement. J Thromb Thrombolysis. 2017 Jul; 44(1):30-37. PMID: 28315167.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    8. Feng S, Kroll MH, Nick AM, Sood AK, Afshar-Kharghan V. Platelets are not hyperreactive in patients with ovarian cancer. Platelets. 2016 Nov; 27(7):716-718. PMID: 27185008.
      Citations: 5     Fields:    Translation:HumansCells
    9. Maiti A, Short NJ, Kroll MH. Indiscriminate Testing for Heparin-Induced Thrombocytopenia: A Teachable Moment. JAMA Intern Med. 2016 05 01; 176(5):592-3. PMID: 27043083.
      Citations:    Fields:    Translation:Humans
    10. Shoultz-Henley S, Garden AS, Mohamed AS, Sheu T, Kroll MH, Rosenthal DI, Gunn GB, Hayes AJ, French C, Eichelberger H, Kalpathy-Cramer J, Smith BD, Phan J, Ayoub Z, Lai SY, Pham B, Kies M, Gold KA, Sturgis E, Fuller CD. Prognostic value of pretherapy platelet elevation in oropharyngeal cancer patients treated with chemoradiation. Int J Cancer. 2016 Mar 01; 138(5):1290-7. PMID: 26414107.
      Citations: 7     Fields:    Translation:Humans
    11. Alattar ML, Ciccone M, Gaballa MR, Vitale C, Badoux XC, Manoukian G, Keating MJ, Kroll MH, Ferrajoli A. Bleeding diathesis associated with acquired von Willebrand Syndrome in three patients with chronic lymphocytic leukemia. Leuk Lymphoma. 2015; 56(12):3452-4. PMID: 25926060.
      Citations: 2     Fields:    Translation:Humans
    12. Prescott LS, Kidin LM, Downs RL, Cleveland DJ, Wilson GL, Munsell MF, DeJesus AY, Cain KE, Ramirez PT, Kroll MH, Levenback CF, Schmeler KM. Improved compliance with venous thromboembolism pharmacologic prophylaxis for patients with gynecologic malignancies hospitalized for nonsurgical indications did not reduce venous thromboembolism incidence. Int J Gynecol Cancer. 2015 Jan; 25(1):152-9. PMID: 25365592.
      Citations:    Fields:    Translation:Humans
    13. Kroll MH, Michaelis LC, Verstovsek S. Mechanisms of thrombogenesis in polycythemia vera. Blood Rev. 2015 Jul; 29(4):215-21. PMID: 25577686.
      Citations: 24     Fields:    Translation:Humans
    14. Vu K, Luong NV, Hubbard J, Zalpour A, Faderl S, Thomas DA, Yang D, Kantarjian H, Kroll MH. A retrospective study of venous thromboembolism in acute leukemia patients treated at the University of Texas MD Anderson Cancer Center. Cancer Med. 2015 Jan; 4(1):27-35. PMID: 25487644.
      Citations: 13     Fields:    Translation:Humans
    15. Feng S, Liang X, Kroll MH, Chung DW, Afshar-Kharghan V. von Willebrand factor is a cofactor in complement regulation. Blood. 2015 Feb 05; 125(6):1034-7. PMID: 25395424.
      Citations: 24     Fields:    Translation:HumansCells
    16. Feng S, Liang X, Cruz MA, Vu H, Zhou Z, Pemmaraju N, Dong JF, Kroll MH, Afshar-Kharghan V. The interaction between factor H and Von Willebrand factor. PLoS One. 2013; 8(8):e73715. PMID: 23991205.
      Citations: 18     Fields:    Translation:HumansCells
    17. Feng S, Eyler SJ, Zhang Y, Maga T, Nester CM, Kroll MH, Smith RJ, Afshar-Kharghan V. Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome. Blood. 2013 Aug 22; 122(8):1487-93. PMID: 23847193.
      Citations: 32     Fields:    Translation:Humans
    18. Schmeler KM, Wilson GL, Cain K, Munsell MF, Ramirez PT, Soliman PT, Nick AM, Frumovitz M, Coleman RL, Kroll MH, Levenback CF. Venous thromboembolism (VTE) rates following the implementation of extended duration prophylaxis for patients undergoing surgery for gynecologic malignancies. Gynecol Oncol. 2013 Feb; 128(2):204-8. PMID: 23200912.
      Citations: 16     Fields:    Translation:Humans
    19. Feng S, Kroll MH, Nolasco L, Moake J, Afshar-Kharghan V. Complement activation in thrombotic microangiopathies. Br J Haematol. 2013 Feb; 160(3):404-6. PMID: 23116127.
      Citations: 6     Fields:    Translation:Humans
    20. Cho MS, Bottsford-Miller J, Vasquez HG, Stone R, Zand B, Kroll MH, Sood AK, Afshar-Kharghan V. Platelets increase the proliferation of ovarian cancer cells. Blood. 2012 Dec 06; 120(24):4869-72. PMID: 22966171.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    21. Kroll MH, Afshar-Kharghan V. Platelets in pulmonary vascular physiology and pathology. Pulm Circ. 2012 Jul; 2(3):291-308. PMID: 23130099.
      Citations: 11     
    22. Ma Q, Li D, Nurieva R, Patenia R, Bassett R, Cao W, Alekseev AM, He H, Molldrem JJ, Kroll MH, Champlin RE, Sale GE, Afshar-Kharghan V. Reduced graft-versus-host disease in C3-deficient mice is associated with decreased donor Th1/Th17 differentiation. Biol Blood Marrow Transplant. 2012 Aug; 18(8):1174-81. PMID: 22664751.
      Citations: 12     Fields:    Translation:AnimalsCells
    23. Zalpour A, Kroll MH, Afshar-Kharghan V, Yusuf SW, Escalante C. Role of factor xa inhibitors in cancer-associated thrombosis: any new data? Adv Hematol. 2011; 2011:196135. PMID: 22013445.
      Citations: 3     
    24. Iliescu C, Durand JB, Kroll M. Cardiovascular interventions in thrombocytopenic cancer patients. Tex Heart Inst J. 2011; 38(3):259-60. PMID: 21720465.
      Citations: 15     Fields:    Translation:Humans
    25. Kroll MH. If Virchow were to meet Newton. Blood. 2010 Mar 18; 115(11):2123-4. PMID: 20299520.
      Citations: 2     Fields:    
    26. Dong JF, Cruz MA, Aboulfatova K, Martin C, Choi H, Bergeron AL, Martini SR, Kroll MH, Kent TA. Magnesium maintains endothelial integrity, up-regulates proteolysis of ultra-large von Willebrand factor, and reduces platelet aggregation under flow conditions. Thromb Haemost. 2008 Mar; 99(3):586-93. PMID: 18327408.
      Citations: 14     Fields:    Translation:HumansCells
    27. Reséndiz JC, Kroll MH, Lassila R. Protease-activated receptor-induced Akt activation--regulation and possible function. J Thromb Haemost. 2007 Dec; 5(12):2484-93. PMID: 17883592.
      Citations: 19     Fields:    Translation:HumansCells
    28. Feng S, Lu X, Reséndiz JC, Kroll MH. Pathological shear stress directly regulates platelet alphaIIbbeta3 signaling. Am J Physiol Cell Physiol. 2006 Dec; 291(6):C1346-54. PMID: 16822941.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    29. Kroll MH, Feng S. Targeting shear stress-induced platelet activation: is lesion-specific antiplatelet therapy a realistic clinical goal? Expert Rev Cardiovasc Ther. 2005 Sep; 3(5):941-51. PMID: 16181038.
      Citations: 4     Fields:    Translation:HumansAnimals
    30. Hassan AA, Kroll MH. Acquired disorders of platelet function. Hematology Am Soc Hematol Educ Program. 2005; 403-8. PMID: 16304411.
      Citations: 4     Fields:    Translation:HumansCells
    31. Feng S, Lu X, Kroll MH. Filamin A binding stabilizes nascent glycoprotein Ibalpha trafficking and thereby enhances its surface expression. J Biol Chem. 2005 Feb 25; 280(8):6709-15. PMID: 15623510.
      Citations: 16     Fields:    Translation:AnimalsCells
    32. Sun L, Feng S, Reséndiz JC, Lu X, Durante W, Kroll MH. Role of the Pyk2-MAP kinase-cPLA2 signaling pathway in shear-dependent platelet aggregation. Ann Biomed Eng. 2004 Sep; 32(9):1193-201. PMID: 15493507.
      Citations: 4     Fields:    Translation:HumansCells
    33. Franceschi F, Christodoulides N, Kroll MH, Genta RM. Helicobacter pylori and idiopathic thrombocytopenic purpura. Ann Intern Med. 2004 May 04; 140(9):766-7. PMID: 15126268.
      Citations: 17     Fields:    Translation:HumansCells
    34. Feng S, Reséndiz JC, Lu X, Kroll MH. Filamin A binding to the cytoplasmic tail of glycoprotein Ibalpha regulates von Willebrand factor-induced platelet activation. Blood. 2003 Sep 15; 102(6):2122-9. PMID: 12791664.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    35. Reséndiz JC, Feng S, Ji G, Francis KA, Berndt MC, Kroll MH. Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation. Mol Pharmacol. 2003 Mar; 63(3):639-45. PMID: 12606772.
      Citations: 3     Fields:    Translation:HumansCells
    36. Massarweh S, Udden MM, Shahab I, Kroll M, Sears DA, Lynch GR, Teh BS, Lu HH. HIV-related Hodgkin's disease with central nervous system involvement and association with Epstein-Barr virus. Am J Hematol. 2003 Mar; 72(3):216-9. PMID: 12605396.
      Citations: 3     Fields:    Translation:HumansCells
    37. Vilchez RA, Jorgensen JL, Kroll MH. Systemic non-Hodgkin lymphoma in HIV-infected patients in the era of highly active antiretroviral therapy. Blood. 2002 Jun 01; 99(11):4250-1. PMID: 12043698.
      Citations: 2     Fields:    Translation:Humans
    38. Anstadt MP, Carwile JM, Guill CK, Conklin LD, Soltero ER, Lucci A, Kroll MH. Relapse of thrombotic thrombocytopenic purpura associated with decreased VWF cleaving activity. Am J Med Sci. 2002 May; 323(5):281-4. PMID: 12018674.
      Citations: 3     Fields:    Translation:Humans
    39. Vilchez RA, Kozinetz CA, Jorgensen JL, Kroll MH, Butel JS. AIDS-related systemic non-Hodgkin's lymphoma at a large community program. AIDS Res Hum Retroviruses. 2002 Mar 01; 18(4):237-42. PMID: 11860669.
      Citations: 4     Fields:    Translation:HumansCells
    40. Feng S, Reséndiz JC, Christodoulides N, Lu X, Arboleda D, Berndt MC, Kroll MH. Pathological shear stress stimulates the tyrosine phosphorylation of alpha-actinin associated with the glycoprotein Ib-IX complex. Biochemistry. 2002 Jan 29; 41(4):1100-8. PMID: 11802708.
      Citations: 1     Fields:    Translation:HumansCells
    41. Teh BS, Lu HH, Lynch GR, Banez E, Kroll MH. AIDS-related Kaposi's sarcoma involving bone and bone marrow. South Med J. 1999 Jan; 92(1):61-4. PMID: 9932830.
      Citations: 3     Fields:    Translation:Humans
    42. Kroll MH, Shandera WX. AIDS-associated Kaposi's sarcoma. Hosp Pract (1995). 1998 Apr 15; 33(4):85-8, 95-6, 99-102. PMID: 9562835.
      Citations:    Fields:    Translation:Humans
    43. Andrews RK, Kroll MH, Ward CM, Rose JW, Scarborough RM, Smith AI, López JA, Berndt MC. Binding of a novel 50-kilodalton alboaggregin from Trimeresurus albolabris and related viper venom proteins to the platelet membrane glycoprotein Ib-IX-V complex. Effect on platelet aggregation and glycoprotein Ib-mediated platelet activation. Biochemistry. 1996 Sep 24; 35(38):12629-39. PMID: 8823201.
      Citations: 8     Fields:    Translation:AnimalsCells
    44. Wagner CT, Kroll MH, Chow TW, Hellums JD, Schafer AI. Epinephrine and shear stress synergistically induce platelet aggregation via a mechanism that partially bypasses VWF-GP IB interactions. Biorheology. 1996 May-Jun; 33(3):209-29. PMID: 8935180.
      Citations: 5     Fields:    Translation:Humans
    45. McCrary JK, Nolasco LH, Hellums JD, Kroll MH, Turner NA, Moake JL. Direct demonstration of radiolabeled von Willebrand factor binding to platelet glycoprotein Ib and IIb-IIIa in the presence of shear stress. Ann Biomed Eng. 1995 Nov-Dec; 23(6):787-93. PMID: 8572428.
      Citations: 7     Fields:    Translation:HumansCells
    46. Christodoulides N, Durante W, Kroll MH, Schafer AI. Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation. 1995 May 01; 91(9):2306-9. PMID: 7729015.
      Citations: 45     Fields:    Translation:AnimalsCells
    47. Razdan K, Hellums JD, Kroll MH. Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s). Biochem J. 1994 Sep 15; 302 ( Pt 3):681-6. PMID: 7524475.
      Citations: 6     Fields:    Translation:HumansCells
    48. Michelson AD, Benoit SE, Kroll MH, Li JM, Rohrer MJ, Kestin AS, Barnard MR. The activation-induced decrease in the platelet surface expression of the glycoprotein Ib-IX complex is reversible. Blood. 1994 Jun 15; 83(12):3562-73. PMID: 8204882.
      Citations: 4     Fields:    Translation:HumansCells
    49. Rumbaut RE, Kroll MH, Gyorkey F, Schafer AI. Acquired platelet storage pool deficiency due to severe valvular disease corrected by prosthetic valve replacement. Am J Hematol. 1994 Mar; 45(3):272-3. PMID: 8296805.
      Citations:    Fields:    Translation:Humans
    50. Kroll MH, Hellums JD, Guo Z, Durante W, Razdan K, Hrbolich JK, Schafer AI. Protein kinase C is activated in platelets subjected to pathological shear stress. J Biol Chem. 1993 Feb 15; 268(5):3520-4. PMID: 8429027.
      Citations: 14     Fields:    Translation:HumansCells
    51. Durante W, Schini VB, Catovsky S, Kroll MH, Vanhoutte PM, Schafer AI. Plasmin potentiates induction of nitric oxide synthesis by interleukin-1 beta in vascular smooth muscle cells. Am J Physiol. 1993 Feb; 264(2 Pt 2):H617-24. PMID: 8447474.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    52. Schafer AI, Kroll MH. Nonatheromatous arterial thrombosis. Annu Rev Med. 1993; 44:155-70. PMID: 8476237.
      Citations: 2     Fields:    Translation:Humans
    53. Kroll MH, Mendelsohn ME, Miller JL, Ballen KK, Hrbolich JK, Schafer AI. Monoclonal antibody AG-1 initiates platelet activation by a pathway dependent on glycoprotein IIb-IIIa and extracellular calcium. Biochim Biophys Acta. 1992 Nov 17; 1137(3):248-56. PMID: 1332779.
      Citations: 3     Fields:    Translation:HumansCells
    54. Chow TW, Hellums JD, Moake JL, Kroll MH. Shear stress-induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation. Blood. 1992 Jul 01; 80(1):113-20. PMID: 1611079.
      Citations: 46     Fields:    Translation:HumansCells
    55. Durante W, Schini VB, Scott-Burden T, Junquero DC, Kroll MH, Vanhoutte PM, Schafer AI. Platelet inhibition by an L-arginine-derived substance released by IL-1 beta-treated vascular smooth muscle cells. Am J Physiol. 1991 Dec; 261(6 Pt 2):H2024-30. PMID: 1661096.
      Citations: 3     Fields:    Translation:AnimalsCells
    56. Luzzatto G, Kroll MH, Zavoico GB, Schafer AI. Regulation of the phosphoinositide cycle by Na+/H+ exchange and intracellular pH in human platelets. Biochim Biophys Acta. 1991 Jun 19; 1084(1):78-86. PMID: 1647205.
      Citations: 3     Fields:    Translation:HumansCells
    57. Hechtman DH, Kroll MH, Gimbrone MA, Schafer AI. Platelet interaction with vascular smooth muscle in synthesis of prostacyclin. Am J Physiol. 1991 May; 260(5 Pt 2):H1544-51. PMID: 1903602.
      Citations:    Fields:    Translation:AnimalsCells
    58. Kroll MH, Schafer AI. Biochemical mechanisms of platelet activation. Blood. 1989 Sep; 74(4):1181-95. PMID: 2669994.
      Citations: 57     Fields:    Translation:HumansCells
    59. Kroll MH, Zavoico GB, Schafer AI. Second messenger function of phosphatidic acid in platelet activation. J Cell Physiol. 1989 Jun; 139(3):558-64. PMID: 2738101.
      Citations: 19     Fields:    Translation:HumansCells
    60. Takayama H, Kroll MH, Gimbrone MA, Schafer AI. Turnover of eicosanoid precursor fatty acids among phospholipid classes and subclasses of cultured human umbilical vein endothelial cells. Biochem J. 1989 Mar 01; 258(2):427-34. PMID: 2495792.
      Citations: 5     Fields:    Translation:HumansCells
    61. Kroll MH, Zavoico GB, Schafer AI. Control of platelet protein kinase C activation by cyclic AMP. Biochim Biophys Acta. 1988 Jun 08; 970(1):61-7. PMID: 2835990.
      Citations: 3     Fields:    Translation:HumansCells
    62. Endothelium-derived relaxing factor inhibits shear stress-induced platelet aggregation. Platelets. 4:135-140.
    63. Alpha actinin binds to glycoprotein (GP) IBA and functions as an adapter for phosphoinositide (PI) 3-kinase in shear stress-activated platelets. Blood. 96.
    64. Venous thromboembolism (VTE) rates following the implementation of extended duration prophylaxis for patients undergoing surgery for gynecologic malignancies. Obstetrical and Gynecological Survey. 68:439-440.
    65. Mechanisms of thrombogenesis in polycythemia vera. Blood Reviews. 29:215-221.
    66. Bleeding diathesis associated with acquired von Willebrand Syndrome in three patients with chronic lymphocytic leukemia. Leukemia and Lymphoma. 56:3452-3454.
    67. Acquired disorders of platelet function. 225-241.
    68. Prognostic value of pretherapy platelet elevation in oropharyngeal cancer patients treated with chemoradiation. International Journal of Cancer. 138:1290-1297.
    69. Streptokinase inhibits acute platelet thrombus formation in stenosed dog coronary arteries. Platelets. 2:145-152.
    70. Nitric oxide induces heme oxygenase-1 expression in vascular smooth muscle cells. FASEB Journal. 10.
    71. Platelets are not hyperreactive in patients with ovarian cancer. Platelets. 1-3.
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