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MARY ELIZABETH EDGERTON

TitleAssociate Professor
InstitutionMD Anderson
DepartmentPathology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang S, Oh DY, Leventaki V, Drakos E, Zhang R, Sahin AA, Resetkova E, Edgerton ME, Wu W, Claret FX. MicroRNA-17 acts as a tumor chemosensitizer by targeting JAB1/CSN5 in triple-negative breast cancer. Cancer Lett. 2019 11 28; 465:12-23. PMID: 31473252.
      View in: PubMed
    2. Casasent AK, Schalck A, Gao R, Sei E, Long A, Pangburn W, Casasent T, Meric-Bernstam F, Edgerton ME, Navin NE. Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing. Cell. 2018 01 11; 172(1-2):205-217.e12. PMID: 29307488.
      View in: PubMed
    3. Kuerer HM, Smith BD, Chavez-MacGregor M, Albarracin C, Barcenas CH, Santiago L, Edgerton ME, Rauch GM, Giordano SH, Sahin A, Krishnamurthy S, Woodward W, Tripathy D, Yang WT, Hunt KK. DCIS Margins and Breast Conservation: MD Anderson Cancer Center Multidisciplinary Practice Guidelines and Outcomes. J Cancer. 2017; 8(14):2653-2662. PMID: 28928852.
      View in: PubMed
    4. Casasent AK, Edgerton M, Navin NE. Genome evolution in ductal carcinoma in situ: invasion of the clones. J Pathol. 2017 Jan; 241(2):208-218. PMID: 27861897.
      View in: PubMed
    5. Freedman RS, Cantor SB, Merriman KW, Edgerton ME. 2013 HIPAA Changes Provide Opportunities and Challenges for Researchers: Perspectives from a Cancer Center. Clin Cancer Res. 2016 Feb 01; 22(3):533-9. PMID: 26832744.
      View in: PubMed
    6. Han L, Yuan Y, Zheng S, Yang Y, Li J, Edgerton ME, Diao L, Xu Y, Verhaak RGW, Liang H. The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes. Nat Commun. 2014 Jul 07; 5:3963. PMID: 24999802.
      View in: PubMed
    7. Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 2013 Oct; 45(10):1113-20. PMID: 24071849.
      View in: PubMed
    8. Rog CJ, Chekuri SC, Edgerton ME. Challenges of the information age: the impact of false discovery on pathway identification. BMC Res Notes. 2012 Nov 21; 5:647. PMID: 23171633.
      View in: PubMed
    9. Macklin P, Edgerton ME, Thompson AM, Cristini V. Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression. J Theor Biol. 2012 May 21; 301:122-40. PMID: 22342935.
      View in: PubMed
    10. Perry KD, Reynolds C, Rosen DG, Edgerton ME, T Albarracin C, Gilcrease MZ, Sahin AA, Abraham SC, Wu Y. Metastatic neuroendocrine tumour in the breast: a potential mimic of in-situ and invasive mammary carcinoma. Histopathology. 2011 Oct; 59(4):619-30. PMID: 22014043.
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    11. Thompson PA, Brewster AM, Kim-Anh D, Baladandayuthapani V, Broom BM, Edgerton ME, Hahn KM, Murray JL, Sahin A, Tsavachidis S, Wang Y, Zhang L, Hortobagyi GN, Mills GB, Bondy ML. Selective genomic copy number imbalances and probability of recurrence in early-stage breast cancer. PLoS One. 2011; 6(8):e23543. PMID: 21858162.
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    12. Brewster AM, Thompson P, Sahin AA, Do K, Edgerton M, Murray JL, Tsavachidis S, Zhou R, Liu Y, Zhang L, Mills G, Bondy M. Copy number imbalances between screen- and symptom-detected breast cancers and impact on disease-free survival. Cancer Prev Res (Phila). 2011 Oct; 4(10):1609-16. PMID: 21795423.
      View in: PubMed
    13. Frey LJ, Piccolo SR, Edgerton ME. Multiplicity: an organizing principle for cancers and somatic mutations. BMC Med Genomics. 2011 Jun 29; 4:52. PMID: 21714919.
      View in: PubMed
    14. Edgerton ME, Chuang YL, Macklin P, Yang W, Bearer EL, Cristini V. A novel, patient-specific mathematical pathology approach for assessment of surgical volume: application to ductal carcinoma in situ of the breast. Anal Cell Pathol (Amst). 2011; 34(5):247-63. PMID: 21988888.
      View in: PubMed
    15. Edgerton ME, Grizzle WE, Washington MK. The deployment of a tissue request tracking system for the CHTN: a case study in managing change in informatics for biobanking operations. BMC Med Inform Decis Mak. 2010 Jun 02; 10:32. PMID: 20525187.
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    16. Albarracin C, Edgerton ME, Gilcrease MZ, Huo L, Krishnamurthy S, Middleton LP, Resetkova E, Sahin AA, Sneige N, Fraser WS, Wu Y. Is it too soon to start reporting HER2 genetic heterogeneity? Arch Pathol Lab Med. 2010 Feb; 134(2):162-3; author reply 163. PMID: 20121597.
      View in: PubMed
    17. Broom BM, Sulman EP, Do KA, Edgerton ME. Bagged gene shaving for the robust clustering of high-throughput data. Int J Bioinform Res Appl. 2010; 6(4):326-43. PMID: 20940121.
      View in: PubMed
    18. Sanga S, Broom BM, Cristini V, Edgerton ME. Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family. BMC Med Genomics. 2009 Sep 11; 2:59. PMID: 19747394.
      View in: PubMed
    19. Frieboes HB, Edgerton ME, Fruehauf JP, Rose FR, Worrall LK, Gatenby RA, Ferrari M, Cristini V. Prediction of drug response in breast cancer using integrative experimental/computational modeling. Cancer Res. 2009 May 15; 69(10):4484-92. PMID: 19366802.
      View in: PubMed
    20. Kuerer HM, Albarracin CT, Yang WT, Cardiff RD, Brewster AM, Symmans WF, Hylton NM, Middleton LP, Krishnamurthy S, Perkins GH, Babiera G, Edgerton ME, Czerniecki BJ, Arun BK, Hortobagyi GN. Ductal carcinoma in situ: state of the science and roadmap to advance the field. J Clin Oncol. 2009 Jan 10; 27(2):279-88. PMID: 19064970.
      View in: PubMed
    21. Riben M, Wade G, Edgerton M, Kilbourne J. Aligning tissue banking data models for caBIG interoperability. AMIA Annu Symp Proc. 2008 Nov 06; 1109. PMID: 18999005.
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    22. Edgerton ME, Morrison C, LiVolsi VA, Moskaluk CA, Qualman SJ, Washington MK, Grizzle WE. A standards based ontological approach to information handling for use by organizations providing human tissue for research. Cancer Inform. 2008; 6:127-37. PMID: 19259407.
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    23. Khalifeh IM, Albarracin C, Diaz LK, Symmans FW, Edgerton ME, Hwang RF, Sneige N. Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma. Am J Surg Pathol. 2008 Apr; 32(4):544-52. PMID: 18300793.
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    24. Edgerton ME, Fisher DH, Tang L, Frey LJ, Chen Z. Data mining for gene networks relevant to poor prognosis in lung cancer via backward-chaining rule induction. Cancer Inform. 2007 Feb 10; 3:93-114. PMID: 19455237.
      View in: PubMed
    25. Frey L, Edgerton M, Fisher D, Levy S. Ensemble stump classifiers and gene expression signatures in lung cancer. Stud Health Technol Inform. 2007; 129(Pt 2):1255-9. PMID: 17911916.
      View in: PubMed
    26. Frey L, Edgerton ME, Fisher DH, Tang L, Chen Z. Using prior knowledge and rule induction methods to discover molecular markers of prognosis in lung cancer. AMIA Annu Symp Proc. 2005; 256-60. PMID: 16779041.
      View in: PubMed
    27. Massion PP, Taflan PM, Shyr Y, Rahman SM, Yildiz P, Shakthour B, Edgerton ME, Ninan M, Andersen JJ, Gonzalez AL. Early involvement of the phosphatidylinositol 3-kinase/Akt pathway in lung cancer progression. Am J Respir Crit Care Med. 2004 Nov 15; 170(10):1088-94. PMID: 15317667.
      View in: PubMed
    28. Massion PP, Taflan PM, Jamshedur Rahman SM, Yildiz P, Shyr Y, Edgerton ME, Westfall MD, Roberts JR, Pietenpol JA, Carbone DP, Gonzalez AL. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Res. 2003 Nov 01; 63(21):7113-21. PMID: 14612504.
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    29. Yamagata N, Shyr Y, Yanagisawa K, Edgerton M, Dang TP, Gonzalez A, Nadaf S, Larsen P, Roberts JR, Nesbitt JC, Jensen R, Levy S, Moore JH, Minna JD, Carbone DP. A training-testing approach to the molecular classification of resected non-small cell lung cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4695-704. PMID: 14581339.
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    30. Xie L, Law BK, Aakre ME, Edgerton M, Shyr Y, Bhowmick NA, Moses HL. Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res. 2003; 5(6):R187-98. PMID: 14580254.
      View in: PubMed
    31. Yanagisawa K, Shyr Y, Xu BJ, Massion PP, Larsen PH, White BC, Roberts JR, Edgerton M, Gonzalez A, Nadaf S, Moore JH, Caprioli RM, Carbone DP. Proteomic patterns of tumour subsets in non-small-cell lung cancer. Lancet. 2003 Aug 09; 362(9382):433-9. PMID: 12927430.
      View in: PubMed
    32. Berman JJ, Edgerton ME, Friedman BA. The tissue microarray data exchange specification: a community-based, open source tool for sharing tissue microarray data. BMC Med Inform Decis Mak. 2003 May 23; 3:5. PMID: 12769826.
      View in: PubMed
    33. Edgerton ME, Taylor R, Powell JI, Hunter L, Simon R, Liu ET. A bioinformatics tool to select sequences for microarray studies of mouse models of oncogenesis. Bioinformatics. 2002 May; 18(5):774-5. PMID: 12050079.
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    34. Simpson JF, Page DL, Edgerton ME. p53 in Mammary ductal carcinoma in situ, mutations in high-grade lesions only? J Natl Cancer Inst. 2001 May 02; 93(9):666-7. PMID: 11333279.
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    35. Edgerton ME, Hoda RS, Gupta PK. Cytologic diagnosis of metastatic ovarian adenocarcinoma in the urinary bladder: a case report and review of the literature. Diagn Cytopathol. 1999 Mar; 20(3):156-9. PMID: 10086240.
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    36. Morel DW, Edgerton ME, Warner GE, Johnson WJ, Phillips MC, Rothblat GH. Comparison of the intracellular metabolism and trafficking of 25-hydroxycholesterol and cholesterol in macrophages. J Lipid Res. 1996 Sep; 37(9):2041-51. PMID: 8895069.
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    37. Edgerton ME, Brimblecombe P. Thermodynamics of halobacterial environments. Can J Microbiol. 1981 Sep; 27(9):899-909. PMID: 7306878.
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    38. Edgerton ME, Moore TA, Greenwood C. Investigations into the effect of acid on the spectral and kinetic properties of purple membrane from Halobacterium halobium. Biochem J. 1980 Sep 01; 189(3):413-20. PMID: 7213336.
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    39. Edgerton ME, Greenwood C. Evidence for a model of regeneration of a protonated species, bR, from a phototransient, M, in the photochemical cycle of bacteriorhodopsin from Halobacterium halobium [proceedings]. Biochem Soc Trans. 1979 Oct; 7(5):1075-7. PMID: 41777.
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    40. Edgerton ME, Moore TA, Greenwood C. Salt reversal of the acid-induced changes in purple membrane from Halobacterium halobium. FEBS Lett. 1978 Nov 01; 95(1):35-9. PMID: 31300.
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    41. Moore TA, Edgerton ME, Parr G, Greenwood C, Perham RN. Studies of an acid-induced species of purple membrane from Halobacterium halobium. Biochem J. 1978 May 01; 171(2):469-76. PMID: 26337.
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    42. Genome evolution in ductal carcinoma in situ. Journal of Pathology. 241:208-218.
    43. Discrete cell modeling. 88-122.
    44. Searching for meaningful feature interactions with backward-chaining rule induction. 86-96.
    45. Agent-based cell modeling. 206-234.
    46. The tissue microarray data exchange specification. BMC Medical Informatics and Decision Making. 3:1-9.
    47. Backward chaining rule induction. Intelligent Data Analysis. 10:397-417.
    48. Neural network with K-means clustering via PCA for gene expression profile analysis. 670-673.
    49. Ensemble stump classifiers and gene expression signatures in lung cancer. 1255-1259.
    50. 2013 HIPAA Changes Provide Opportunities and Challenges for Researchers. Clinical Cancer Research. 22:533-539.
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