Loading...
Header Logo
Keywords
Last Name
Institution

LISA S CHEN

TitleAssistant Professor
InstitutionMD Anderson
DepartmentExperimental Therapeutics
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Olsen JB, Cao XJ, Han B, Chen LH, Horvath A, Richardson TI, Campbell RM, Garcia BA, Nguyen H. Quantitative Profiling of the Activity of Protein Lysine Methyltransferase SMYD2 Using SILAC-Based Proteomics. Mol Cell Proteomics. 2016 Mar; 15(3):892-905. PMID: 26750096.
      View in: PubMed
    2. Nguyen H, Allali-Hassani A, Antonysamy S, Chang S, Chen LH, Curtis C, Emtage S, Fan L, Gheyi T, Li F, Liu S, Martin JR, Mendel D, Olsen JB, Pelletier L, Shatseva T, Wu S, Zhang FF, Arrowsmith CH, Brown PJ, Campbell RM, Garcia BA, Barsyte-Lovejoy D, Mader M, Vedadi M. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J Biol Chem. 2015 May 29; 290(22):13641-53. PMID: 25825497.
      View in: PubMed
    3. Chen LS, Keating MJ, Gandhi V. Blood collection methods affect cellular protein integrity: implications for clinical trial biomarkers and ZAP-70 in CLL. Blood. 2014 Aug 14; 124(7):1192-5. PMID: 25124785.
      View in: PubMed
    4. Yang Q, Chen LS, Gandhi V. Mechanism-based combinations with Pim kinase inhibitors in cancer treatments. Curr Pharm Des. 2014; 20(42):6670-81. PMID: 25341939.
      View in: PubMed
    5. Patel V, Chen LS, Wierda WG, Balakrishnan K, Gandhi V. Impact of bone marrow stromal cells on Bcl-2 family members in chronic lymphocytic leukemia. Leuk Lymphoma. 2014 Apr; 55(4):899-910. PMID: 23837491.
      View in: PubMed
    6. Yang Q, Chen LS, Neelapu SS, Gandhi V. Combination of Pim kinase inhibitor SGI-1776 and bendamustine in B-cell lymphoma. Clin Lymphoma Myeloma Leuk. 2013 Sep; 13 Suppl 2:S355-62. PMID: 24290221.
      View in: PubMed
    7. Cervantes-Gomez F, Chen LS, Orlowski RZ, Gandhi V. Biological effects of the Pim kinase inhibitor, SGI-1776, in multiple myeloma. Clin Lymphoma Myeloma Leuk. 2013 Sep; 13 Suppl 2:S317-29. PMID: 23988451.
      View in: PubMed
    8. Ming W, Ma W, Chen LH, Volk C, Michael MD, Xu Y, Zhang F, Wang X. Development and validation of a 96-well cellular assay for the discovery of ALDH1A1 inhibitors. Assay Drug Dev Technol. 2013 Jul; 11(6):388-95. PMID: 23957476.
      View in: PubMed
    9. Yang Q, Chen LS, Neelapu SS, Miranda RN, Medeiros LJ, Gandhi V. Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma. Blood. 2012 Oct 25; 120(17):3491-500. PMID: 22955922.
      View in: PubMed
    10. Pillai RN, Chen LS, Ayres ML, Nowak BJ, Thomas MW, Shpall EJ, Keating MJ, Gandhi V. Multifaceted actions of 8-amino-adenosine kill BCR-ABL positive cells. Leuk Lymphoma. 2012 Oct; 53(10):2024-32. PMID: 22448923.
      View in: PubMed
    11. Stellrecht CM, Chen LS. Transcription inhibition as a therapeutic target for cancer. Cancers (Basel). 2011 Nov 23; 3(4):4170-90. PMID: 24213132.
      View in: PubMed
    12. Chen LS, Redkar S, Taverna P, Cortes JE, Gandhi V. Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia. Blood. 2011 Jul 21; 118(3):693-702. PMID: 21628411.
      View in: PubMed
    13. Chen LS, Balakrishnan K, Gandhi V. Inflammation and survival pathways: chronic lymphocytic leukemia as a model system. Biochem Pharmacol. 2010 Dec 15; 80(12):1936-45. PMID: 20696142.
      View in: PubMed
    14. Zhang S, Chen L, Jung EJ, Calin GA. Targeting microRNAs with small molecules: from dream to reality. Clin Pharmacol Ther. 2010 Jun; 87(6):754-8. PMID: 20428111.
      View in: PubMed
    15. Chen LS, Du-Cuny L, Vethantham V, Hawke DH, Manley JL, Zhang S, Gandhi V. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochem Pharmacol. 2010 Mar 01; 79(5):669-77. PMID: 19814999.
      View in: PubMed
    16. Chen LS, Redkar S, Bearss D, Wierda WG, Gandhi V. Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells. Blood. 2009 Nov 05; 114(19):4150-7. PMID: 19734450.
      View in: PubMed
    17. Chen LS, Nowak BJ, Ayres ML, Krett NL, Rosen ST, Zhang S, Gandhi V. Inhibition of ATP synthase by chlorinated adenosine analogue. Biochem Pharmacol. 2009 Sep 15; 78(6):583-91. PMID: 19477165.
      View in: PubMed
    18. Gandhi V, Balakrishnan K, Chen LS. Mcl-1: the 1 in CLL. Blood. 2008 Nov 01; 112(9):3538-40. PMID: 18948586.
      View in: PubMed
    19. Chen LS, Plunkett W, Gandhi V. Polyadenylation inhibition by the triphosphates of deoxyadenosine analogues. Leuk Res. 2008 Oct; 32(10):1573-81. PMID: 18433867.
      View in: PubMed
    20. Chen LS, Stellrecht CM, Gandhi V. RNA-directed agent, cordycepin, induces cell death in multiple myeloma cells. Br J Haematol. 2008 Mar; 140(6):682-391. PMID: 18205859.
      View in: PubMed
    21. Chen LS, Sheppard TL. Chain termination and inhibition of Saccharomyces cerevisiae poly(A) polymerase by C-8-modified ATP analogs. J Biol Chem. 2004 Sep 24; 279(39):40405-11. PMID: 15265873.
      View in: PubMed
    22. Chen LS, Bahr MH, Sheppard TL. Effects of 8-chlorodeoxyadenosine on DNA synthesis by the Klenow fragment of DNA polymerase I. Bioorg Med Chem Lett. 2003 May 05; 13(9):1509-12. PMID: 12699743.
      View in: PubMed
    23. Chen LS, Sheppard TL. Synthesis and hybridization properties of RNA containing 8-chloroadenosine. Nucleosides Nucleotides Nucleic Acids. 2002; 21(8-9):599-617. PMID: 12484453.
      View in: PubMed
    24. Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia. Leukemia and Lymphoma. 1-11.
    25. Synthesis, characterization, redox properties, and representative X-ray structures of four- and five-coordinate copper(II) complexes with polydentate aminopyridine ligands. Inorganica Chimica Acta. 324:1-15.
    26. Pim kinases in aml. 177-199.
    CHEN's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description