WEIGUO ZHANG

TitleAssistant Professor
InstitutionMD Anderson
DepartmentLeukemia
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhang W, Ruvolo VR, Gao C, Zhou L, Bornmann W, Tsao T, Schober WD, Smith P, Guichard S, Konopleva M, Andreeff M. Evaluation of apoptosis induction by concomitant inhibition of MEK, mTOR, and Bcl-2 in human acute myelogenous leukemia cells. . 2014 Jul; 13(7):1848-59. PMID: 24739393.
      Citations:    
    2. Zhang W, Gao C, Konopleva M, Chen Y, Jacamo RO, Borthakur G, Cortes JE, Ravandi F, Ramachandran A, Andreeff M. Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies. Clin Cancer Res. 2014 May 01; 20(9):2363-74. PMID: 24619500.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    3. Ling X, Spaeth E, Chen Y, Shi Y, Zhang W, Schober W, Hail N, Konopleva M, Andreeff M. The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo. PLoS One. 2013; 8(3):e58426. PMID: 23484027.
      Citations: 27     Fields:    Translation:AnimalsCells
    4. Cheng NH, Zhang W, Chen WQ, Jin J, Cui X, Butte NF, Chan L, Hirschi KD. A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis. FEBS J. 2011 Jul; 278(14):2525-2539. PMID: 21575136.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    5. Wen J, Fu J, Zhang W, Guo M. Genetic and epigenetic changes in lung carcinoma and their clinical implications. Mod Pathol. 2011 Jul; 24(7):932-43. PMID: 21423157.
      Citations: 15     Fields:    Translation:Humans
    6. Borthakur G, Kantarjian H, Ravandi F, Zhang W, Konopleva M, Wright JJ, Faderl S, Verstovsek S, Mathews S, Andreeff M, Cortes JE. Phase I study of sorafenib in patients with refractory or relapsed acute leukemias. Haematologica. 2011 Jan; 96(1):62-8. PMID: 20952518.
      Citations: 67     Fields:    Translation:HumansCTClinical Trials
    7. Ling X, Marini F, Konopleva M, Schober W, Shi Y, Burks J, Clise-Dwyer K, Wang RY, Zhang W, Yuan X, Lu H, Caldwell L, Andreeff M. Mesenchymal Stem Cells Overexpressing IFN-ß Inhibit Breast Cancer Growth and Metastases through Stat3 Signaling in a Syngeneic Tumor Model. Cancer Microenviron. 2010 Mar 19; 3(1):83-95. PMID: 21209776.
      Citations:    
    8. Zhang W, Konopleva M, Burks JK, Dywer KC, Schober WD, Yang JY, McQueen TJ, Hung MC, Andreeff M. Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim. Cancer Res. 2010 Mar 15; 70(6):2424-34. PMID: 20215498.
      Citations: 30     Fields:    Translation:HumansCells
    9. Mori S, Cortes J, Kantarjian H, Zhang W, Andreef M, Ravandi F. Potential role of sorafenib in the treatment of acute myeloid leukemia. Leuk Lymphoma. 2008 Dec; 49(12):2246-55. PMID: 19052971.
      Citations: 25     Fields:    Translation:HumansCells
    10. Zhang W, Konopleva M, Shi YX, McQueen T, Harris D, Ling X, Estrov Z, Quintás-Cardama A, Small D, Cortes J, Andreeff M. Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia. J Natl Cancer Inst. 2008 Feb 06; 100(3):184-98. PMID: 18230792.
      Citations: 140     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    11. Zhang W, Konopleva M, Ruvolo VR, McQueen T, Evans RL, Bornmann WG, McCubrey J, Cortes J, Andreeff M. Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway. Leukemia. 2008 Apr; 22(4):808-18. PMID: 18200035.
      Citations: 68     Fields:    Translation:HumansCells
    12. Cui L, Wang Y, Shi Y, Zhang Z, Xia Y, Sun H, Wang S, Chen J, Zhang W, Lu Q, Song L, Wei Q, Zhang R, Wang X. Overexpression of annexin a1 induced by terephthalic acid calculi in rat bladder cancer. Proteomics. 2007 Nov; 7(22):4192-202. PMID: 17994624.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    13. Kannankeril PJ, Mitchell BM, Goonasekera SA, Chelu MG, Zhang W, Sood S, Kearney DL, Danila CI, De Biasi M, Wehrens XH, Pautler RG, Roden DM, Taffet GE, Dirksen RT, Anderson ME, Hamilton SL. Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12179-84. PMID: 16873551.
      Citations: 62     Fields:    Translation:Animals
    14. Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M, Konopleva M. Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia. Cancer Res. 2006 Apr 01; 66(7):3737-46. PMID: 16585200.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    15. Konopleva M, Zhang W, Shi YX, McQueen T, Tsao T, Abdelrahim M, Munsell MF, Johansen M, Yu D, Madden T, Safe SH, Hung MC, Andreeff M. Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells. . 2006 Feb; 5(2):317-28. PMID: 16505105.
      Citations:    
    16. Zhang W, McQueen T, Schober W, Rassidakis G, Andreeff M, Konopleva M. Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation. Leukemia. 2005 Nov; 19(11):1977-84. PMID: 16151469.
      Citations: 10     Fields:    Translation:HumansCells
    17. Zhang W, Shi HY, Zhang M. Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteins. BMC Cancer. 2005 May 20; 5:50. PMID: 15907209.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    18. Latha K, Zhang W, Cella N, Shi HY, Zhang M. Maspin mediates increased tumor cell apoptosis upon induction of the mitochondrial permeability transition. Mol Cell Biol. 2005 Mar; 25(5):1737-48. PMID: 15713631.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    19. Saku T, Cheng J, Jen KY, Tokunaga M, Li J, Zhang W, Liu A, Wu L, Lu Y, Zhou Z, Li Y, Li R, Ouyang J, Yang L, Yu S, Lou T, Wang S, Lin D, Rao H, Lin H, Sderk P, Chen Z, Chen Z, Cai C, Kim H, Hong S. Epstein-Barr virus infected lymphoepithelial carcinomas of the salivary gland in the Russia-Asia area: a clinicopathologic study of 160 cases. Arkh Patol. 2003 Mar-Apr; 65(2):35-9. PMID: 15357246.
      Citations: 7     Fields:    Translation:HumansCells
    20. Abraham S, Zhang W, Greenberg N, Zhang M. Maspin functions as tumor suppressor by increasing cell adhesion to extracellular matrix in prostate tumor cells. J Urol. 2003 Mar; 169(3):1157-61. PMID: 12576872.
      Citations: 24     Fields:    Translation:AnimalsCells
    21. Shi HY, Zhang W, Liang R, Kittrell F, Templeton NS, Medina D, Zhang M. Modeling human breast cancer metastasis in mice: maspin as a paradigm. Histol Histopathol. 2003 01; 18(1):201-6. PMID: 12507299.
      Citations: 16     Fields:    Translation:AnimalsCells
    22. Ohtaké S, Cheng J, Ida H, Suzuki M, Ohshiro K, Zhang W, Saku T. Precancerous foci in pleomorphic adenoma of the salivary gland: recognition of focal carcinoma and atypical tumor cells by P53 immunohistochemistry. J Oral Pathol Med. 2002 Nov; 31(10):590-7. PMID: 12406304.
      Citations: 7     Fields:    Translation:Humans
    23. Zhang W, Zhang M. Tissue microarray analysis of maspin expression and its reverse correlation with mutant p53 in various tumors. Int J Oncol. 2002 Jun; 20(6):1145-50. PMID: 12011991.
      Citations: 9     Fields:    Translation:Humans
    24. Shi HY, Zhang W, Liang R, Abraham S, Kittrell FS, Medina D, Zhang M. Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model. Cancer Res. 2001 Sep 15; 61(18):6945-51. PMID: 11559574.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    25. Zhu P, Zhang W. [The role of matrix vesicles during development of the mineralizing tissues of tooth germ and craniofacial bone]. Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Jan; 35(1):69-71. PMID: 11831972.
      Citations: 1     Fields:    Translation:Animals
    26. Li D, Zhang W, Sahin AA, Hittelman WN. DNA adducts in normal tissue adjacent to breast cancer: a review. Cancer Detect Prev. 1999; 23(6):454-62. PMID: 10571655.
      Citations: 16     Fields:    Translation:HumansCells
    27. Chen J, Aufdemorte TB, Jiang H, Liu AR, Zhang W, Thomas HF. Neoplastic odontogenic epithelial cells express bone sialoprotein. Histochem J. 1998 Jan; 30(1):1-6. PMID: 9539200.
      Citations: 2     Fields:    Translation:Humans
    28. Hamada K, Sakaue M, Alemany R, Zhang WW, Horio Y, Roth JA, Mitchell MF. Adenovirus-mediated transfer of HPV 16 E6/E7 antisense RNA to human cervical cancer cells. Gynecol Oncol. 1996 Nov; 63(2):219-27. PMID: 8910631.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    29. Bao JJ, Zhang WW, Kuo MT. Adenoviral delivery of recombinant DNA into transgenic mice bearing hepatocellular carcinomas. Hum Gene Ther. 1996 Feb 10; 7(3):355-65. PMID: 8835222.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    30. Kleinerman DI, Zhang WW, Lin SH, Nguyen TV, von Eschenbach AC, Hsieh JT. Application of a tumor suppressor (C-CAM1)-expressing recombinant adenovirus in androgen-independent human prostate cancer therapy: a preclinical study. Cancer Res. 1995 Jul 01; 55(13):2831-6. PMID: 7796410.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    31. Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang WW, Kruzel E, et al. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol. 1995 Jun; 15(6):3032-40. PMID: 7539102.
      Citations: 120     Fields:    Translation:HumansCells
    32. Zhang WW, Koch PE, Roth JA. Detection of wild-type contamination in a recombinant adenoviral preparation by PCR. Biotechniques. 1995 Mar; 18(3):444-7. PMID: 7779393.
      Citations: 13     Fields:    Translation:Cells
    33. Dai Y, Schwarz EM, Gu D, Zhang WW, Sarvetnick N, Verma IM. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1401-5. PMID: 7877990.
      Citations: 125     Fields:    Translation:AnimalsCells
    34. Clayman GL, el-Naggar AK, Roth JA, Zhang WW, Goepfert H, Taylor DL, Liu TJ. In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma. Cancer Res. 1995 Jan 01; 55(1):1-6. PMID: 7805018.
      Citations: 19     Fields:    Translation:AnimalsCells
    35. The dual MEK/FLT3 inhibitor E6201 exerts cytotoxic activity against acute myeloid leukemia cells harboring resistance-conferring FLT3 Mutations. Cancer Research. 76:1528-1537.
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