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JIAN GU

TitleAssociate Professor
InstitutionMD Anderson
DepartmentEpidemiology
Address1155 Pressler St
Houston TX 77030-3721
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Meuwissen KPV, van der Toorn A, Gu JW, Zhang TC, Dijkhuizen RM, Joosten EAJ. Active Recharge Burst and Tonic Spinal Cord Stimulation Engage Different Supraspinal Mechanisms: A Functional Magnetic Resonance Imaging Study in Peripherally Injured Chronic Neuropathic Rats. Pain Pract. 2020 06; 20(5):510-521. PMID: 32124540.
      Citations: 7     Fields:    Translation:Animals
    2. Meuwissen KPV, de Vries LE, Gu JW, Zhang TC, Joosten EAJ. Burst and Tonic Spinal Cord Stimulation Both Activate Spinal GABAergic Mechanisms to Attenuate Pain in a Rat Model of Chronic Neuropathic Pain. Pain Pract. 2020 01; 20(1):75-87. PMID: 31424152; PMCID: PMC7004135.
      Citations: 11     Fields:    Translation:Animals
    3. Gu JW, Joosten EAJ. Clarifying the Scientific Knowledge Pertaining to Burst Waveforms in Spinal Cord Stimulation. Neuromodulation. 2019 08; 22(6):758-759. PMID: 31361373.
      Citations:    Fields:    Translation:Animals
    4. Meuwissen KPV, Gu JW, Zhang TC, Joosten EAJ. Response to: Fundamental Differences in Burst Stimulation Waveform Design: Eliminating Confusion in the Marketplace. Neuromodulation. 2018 Oct; 21(7):721-722. PMID: 30255538.
      Citations: 2     Fields:    Translation:Humans
    5. Li S, Ye F, Farber JP, Linderoth B, Zhang T, Gu JW, Moffitt M, Garrett K, Chen J, Foreman RD. Dependence of c-fos Expression on Amplitude of High-Frequency Spinal Cord Stimulation in a Rodent Model. Neuromodulation. 2019 Feb; 22(2):172-178. PMID: 30221804.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Meuwissen KPV, Gu JW, Zhang TC, Joosten EAJ. Burst Spinal Cord Stimulation in Peripherally Injured Chronic Neuropathic Rats: A Delayed Effect. Pain Pract. 2018 11; 18(8):988-996. PMID: 29679457.
      Citations: 7     Fields:    Translation:Animals
    7. Koyama S, Xia J, Leblanc BW, Gu JW, Saab CY. Sub-paresthesia spinal cord stimulation reverses thermal hyperalgesia and modulates low frequency EEG in a rat model of neuropathic pain. Sci Rep. 2018 05 08; 8(1):7181. PMID: 29740068; PMCID: PMC5940806.
      Citations: 11     Fields:    Translation:HumansAnimals
    8. Thomson SJ, Tavakkolizadeh M, Love-Jones S, Patel NK, Gu JW, Bains A, Doan Q, Moffitt M. Effects of Rate on Analgesia in Kilohertz Frequency Spinal Cord Stimulation: Results of the PROCO Randomized Controlled Trial. Neuromodulation. 2018 Jan; 21(1):67-76. PMID: 29220121; PMCID: PMC5814855.
      Citations: 38     Fields:    Translation:Humans
    9. Meuwissen KPV, Gu JW, Zhang TC, Joosten EAJ. Conventional-SCS vs. Burst-SCS and the Behavioral Effect on Mechanical Hypersensitivity in a Rat Model of Chronic Neuropathic Pain: Effect of Amplitude. Neuromodulation. 2018 Jan; 21(1):19-30. PMID: 29178358.
      Citations: 15     Fields:    Translation:Animals
    10. Liu X, Meng QH, Ye Y, Hildebrandt MA, Gu J, Wu X. Prognostic significance of pretreatment serum levels of albumin, LDH and total bilirubin in patients with non-metastatic breast cancer. Carcinogenesis. 2015 Feb; 36(2):243-8. PMID: 25524924.
      Citations: 55     Fields:    Translation:Humans
    11. Melkonian SC, Wang X, Gu J, Matin SF, Tannir NM, Wood CG, Wu X. Mitochondrial DNA copy number in peripheral blood leukocytes and the risk of clear cell renal cell carcinoma. Carcinogenesis. 2015 Feb; 36(2):249-55. PMID: 25524925; PMCID: PMC4322190.
      Citations: 12     Fields:    Translation:HumansCells
    12. Lin J, Blalock JA, Chen M, Ye Y, Gu J, Cohen L, Cinciripini PM, Wu X. Depressive symptoms and short telomere length are associated with increased mortality in bladder cancer patients. Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):336-43. PMID: 25416716; PMCID: PMC4332382.
      Citations: 13     Fields:    Translation:HumansCells
    13. Wen CP, Zhang F, Liang D, Wen C, Gu J, Skinner H, Chow WH, Ye Y, Pu X, Hildebrandt MA, Huang M, Chen CH, Hsiung CA, Tsai MK, Tsao CK, Lippman SM, Wu X. The ability of bilirubin in identifying smokers with higher risk of lung cancer: a large cohort study in conjunction with global metabolomic profiling. Clin Cancer Res. 2015 Jan 01; 21(1):193-200. PMID: 25336700; PMCID: PMC4286447.
      Citations: 21     Fields:    Translation:Humans
    14. Sun Y, Gu J, Ajani JA, Chang DW, Wu X, Stroehlein JR. Genetic and intermediate phenotypic susceptibility markers of gastric cancer in Hispanic Americans: a case-control study. Cancer. 2014 Oct 01; 120(19):3040-8. PMID: 24962126.
      Citations: 17     Fields:    Translation:HumansCells
    15. Wang Y, McKay JD, Rafnar T, Wang Z, Timofeeva MN, Broderick P, Zong X, Laplana M, Wei Y, Han Y, Lloyd A, Delahaye-Sourdeix M, Chubb D, Gaborieau V, Wheeler W, Chatterjee N, Thorleifsson G, Sulem P, Liu G, Kaaks R, Henrion M, Kinnersley B, LeCalvez-Kelm F, Stevens VL, Gapstur SM, Chen WV, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Gabrielsen ME, Skorpen F, Vatten L, Chen C, Goodman G, Benhamou S, Vooder T, Nelis M, Metspalu A, Lener M, Lubinski J, Johansson M, Vineis P, Agudo A, Bueno-de-Mesquita HB, Trichopoulos D, Khaw KT, Riboli E, Lathrop M, Scelo G, Albanes D, Caporaso NE, Ye Y, Gu J, Wu X, Spitz MR, Dienemann H, Su L, Matakidou A, Eisen T, Stefansson K, Risch A, Chanock SJ, Christiani DC, Hung RJ, Brennan P, Landi MT, Houlston RS, Amos CI, Vall?e M, Fabianova E, Nj?lstad I, V?lk K, Clavel-Chapelon F, Johansson M, Weiderpass E, Tj?nneland A, Rosenberger A. Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet. 2014 Jul; 46(7):736-41. PMID: 24880342; PMCID: PMC4074058.
      Citations: 181     Fields:    Translation:Humans
    16. Saxena R, Bjonnes A, Prescott J, Dib P, Natt P, Lane J, Lerner M, Cooper JA, Ye Y, Li KW, Codd V, Brackett D, Mirabello L, Kraft P, Dinney CP, Stowell D, Peyton M, Ralhan S, Wander GS, Mehra NK, Salpea KD, Gu J, Wu X, Mangino M, Hunter DJ, De Vivo I, Humphries SE, Samani NJ, Spector TD, Savage SA, Sanghera DK, Maubaret CG. Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort. Circ Cardiovasc Genet. 2014 Jun; 7(3):287-95. PMID: 24795349; PMCID: PMC4106467.
      Citations: 23     Fields:    Translation:HumansCells
    17. Tan W, Gu J, Huang M, Wu X, Hildebrandt MA. Epigenetic analysis of microRNA genes in tumors from surgically resected lung cancer patients and association with survival. Mol Carcinog. 2015 Jun; 54 Suppl 1:E45-51. PMID: 24665010; PMCID: PMC4814160.
      Citations: 5     Fields:    Translation:HumansCells
    18. Sanchez-Espiridion B, Chen M, Chang JY, Lu C, Chang DW, Roth JA, Wu X, Gu J. Telomere length in peripheral blood leukocytes and lung cancer risk: a large case-control study in Caucasians. Cancer Res. 2014 May 01; 74(9):2476-86. PMID: 24618342; PMCID: PMC4357479.
      Citations: 44     Fields:    Translation:HumansCells
    19. Coscio A, Chang DW, Roth JA, Ye Y, Gu J, Yang P, Wu X. Genetic variants of the Wnt signaling pathway as predictors of recurrence and survival in early-stage non-small cell lung cancer patients. Carcinogenesis. 2014 Jun; 35(6):1284-91. PMID: 24517998; PMCID: PMC4043238.
      Citations: 8     Fields:    Translation:HumansCells
    20. Figueroa JD, Ye Y, Siddiq A, Garcia-Closas M, Chatterjee N, Prokunina-Olsson L, Cortessis VK, Kooperberg C, Cussenot O, Benhamou S, Prescott J, Porru S, Dinney CP, Baris D, Purdue M, Jacobs EJ, Albanes D, Wang Z, Deng X, Chung CC, Tang W, Bas Bueno-de-Mesquita H, Trichopoulos D, Weiderpass E, Krogh V, Dorronsoro M, Travis R, Brenan P, Chang-Claude J, Riboli E, Conti D, Gago-Dominguez M, Stern MC, Pike MC, Van Den Berg D, Yuan JM, Hohensee C, Rodabough R, Cancel-Tassin G, Roupret M, Comperat E, Chen C, De Vivo I, Giovannucci E, Hunter DJ, Kraft P, Lindstrom S, Carta A, Pavanello S, Arici C, Mastrangelo G, Kamat AM, Lerner SP, Barton Grossman H, Lin J, Gu J, Pu X, Hutchinson A, Burdette L, Wheeler W, Kogevinas M, Serra C, Carrato A, Lloreta J, Schwenn M, Karagas MR, Johnson A, Schned A, Armenti KR, Hosain GM, Andriole G, Grubb R, Black A, Ryan Diver W, Gapstur SM, Weinstein SJ, Virtamo J, Haiman CA, Landi MT, Caporaso N, Fraumeni JF, Vineis P, Wu X, Silverman DT, Chanock S, Rothman N, Malats N, Ljungberg B, Clavel-Chapelon F, Tj?nneland A, Tard?n A, Garc?a-Closas R. Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet. 2014 Mar 01; 23(5):1387-98. PMID: 24163127; PMCID: PMC3919005.
      Citations: 74     Fields:    Translation:Humans
    21. Bau DT, Lippman SM, Xu E, Gong Y, Lee JJ, Wu X, Gu J. Short telomere lengths in peripheral blood leukocytes are associated with an increased risk of oral premalignant lesion and oral squamous cell carcinoma. Cancer. 2013 Dec 15; 119(24):4277-83. PMID: 24105340; PMCID: PMC3855186.
      Citations: 16     Fields:    Translation:HumansCells
    22. Xu E, Gu J, Hawk ET, Wang KK, Lai M, Huang M, Ajani J, Wu X. Genome-wide methylation analysis shows similar patterns in Barrett's esophagus and esophageal adenocarcinoma. Carcinogenesis. 2013 Dec; 34(12):2750-6. PMID: 23996928; PMCID: PMC3845893.
      Citations: 21     Fields:    Translation:HumansCells
    23. Xu E, Gong Y, Gu J, Jie L, Ajani JA, Wu X. Risk assessment of esophageal adenocarcinoma using ?-H2AX assay. Cancer Epidemiol Biomarkers Prev. 2013 Oct; 22(10):1797-804. PMID: 23904462; PMCID: PMC3824382.
      Citations: 7     Fields:    Translation:HumansCells
    24. Gu J, Wu X. Re: short telomere length, cancer survival, and cancer risk in 47 102 individuals. J Natl Cancer Inst. 2013 Aug 07; 105(15):1157. PMID: 23868923.
      Citations: 9     Fields:    Translation:HumansCells
    25. Xu E, Sun W, Gu J, Chow WH, Ajani JA, Wu X. Association of mitochondrial DNA copy number in peripheral blood leukocytes with risk of esophageal adenocarcinoma. Carcinogenesis. 2013 Nov; 34(11):2521-4. PMID: 23803692; PMCID: PMC3810839.
      Citations: 19     Fields:    Translation:HumansCells
    26. Wang Y, Gu J, Roth JA, Hildebrandt MA, Lippman SM, Ye Y, Minna JD, Wu X. Pathway-based serum microRNA profiling and survival in patients with advanced stage non-small cell lung cancer. Cancer Res. 2013 Aug 01; 73(15):4801-9. PMID: 23774211; PMCID: PMC3760306.
      Citations: 47     Fields:    Translation:Humans
    27. Wu X, Ajani JA, Gu J, Chang DW, Tan W, Hildebrandt MA, Huang M, Wang KK, Hawk E. MicroRNA expression signatures during malignant progression from Barrett's esophagus to esophageal adenocarcinoma. Cancer Prev Res (Phila). 2013 Mar; 6(3):196-205. PMID: 23466817; PMCID: PMC3608471.
      Citations: 53     Fields:    Translation:HumansCells
    28. Xie H, Wu X, Wang S, Chang D, Pollock RE, Lev D, Gu J. Long telomeres in peripheral blood leukocytes are associated with an increased risk of soft tissue sarcoma. Cancer. 2013 May 15; 119(10):1885-91. PMID: 23408253; PMCID: PMC3807211.
      Citations: 20     Fields:    Translation:HumansCells
    29. Xie H, Lev D, Gong Y, Wang S, Pollock RE, Wu X, Gu J. Reduced mitochondrial DNA copy number in peripheral blood leukocytes increases the risk of soft tissue sarcoma. Carcinogenesis. 2013 May; 34(5):1039-43. PMID: 23349016.
      Citations: 17     Fields:    Translation:HumansCells
    30. He Y, Gong Y, Lin J, Chang DW, Gu J, Roth JA, Wu X. Ionizing radiation-induced ?-H2AX activity in whole blood culture and the risk of lung cancer. Cancer Epidemiol Biomarkers Prev. 2013 Mar; 22(3):443-51. PMID: 23300022; PMCID: PMC3601549.
      Citations: 3     Fields:    Translation:HumansCells
    31. Gu J, Wang Y, Wu X. MicroRNA in the pathogenesis and prognosis of esophageal cancer. Curr Pharm Des. 2013; 19(7):1292-300. PMID: 23092349.
      Citations: 56     Fields:    Translation:Humans
    32. Andrew AS, Hu T, Gu J, Gui J, Ye Y, Marsit CJ, Kelsey KT, Schned AR, Tanyos SA, Pendleton EM, Mason RA, Morlock EV, Zens MS, Li Z, Moore JH, Wu X, Karagas MR. HSD3B and gene-gene interactions in a pathway-based analysis of genetic susceptibility to bladder cancer. PLoS One. 2012; 7(12):e51301. PMID: 23284679; PMCID: PMC3526593.
      Citations: 8     Fields:    Translation:HumansCells
    33. Pu X, Ye Y, Spitz MR, Wang L, Gu J, Lippman SM, Hildebrandt MA, Hong WK, Minna JD, Roth JA, Yang P, Wu X. Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study. Clin Cancer Res. 2012 Nov 01; 18(21):5983-91. PMID: 22977190; PMCID: PMC3640870.
      Citations: 7     Fields:    Translation:Humans
    34. Gu JW, Herrmann BS, Levine RA, Melcher JR. Brainstem auditory evoked potentials suggest a role for the ventral cochlear nucleus in tinnitus. J Assoc Res Otolaryngol. 2012 Dec; 13(6):819-33. PMID: 22869301; PMCID: PMC3505586.
      Citations: 85     Fields:    Translation:Humans
    35. Chang DW, Gu J, Wu X. Germline prognostic markers for urinary bladder cancer: obstacles and opportunities. Urol Oncol. 2012 Jul-Aug; 30(4):524-32. PMID: 22742565; PMCID: PMC3824379.
      Citations: 9     Fields:    Translation:Humans
    36. Lin M, Eng C, Hawk ET, Huang M, Lin J, Gu J, Ellis LM, Wu X. Identification of polymorphisms in ultraconserved elements associated with clinical outcomes in locally advanced colorectal adenocarcinoma. Cancer. 2012 Dec 15; 118(24):6188-98. PMID: 22673945; PMCID: PMC3465518.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    37. Lin J, Lu C, Stewart DJ, Gu J, Huang M, Chang DW, Lippman SM, Wu X. Systematic evaluation of apoptotic pathway gene polymorphisms and lung cancer risk. Carcinogenesis. 2012 Sep; 33(9):1699-706. PMID: 22665367; PMCID: PMC3514904.
      Citations: 11     Fields:    Translation:HumansCells
    38. Lin M, Gu J, Eng C, Ellis LM, Hildebrandt MA, Lin J, Huang M, Calin GA, Wang D, Dubois RN, Hawk ET, Wu X. Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients. Clin Cancer Res. 2012 Jul 15; 18(14):3982-91. PMID: 22661538; PMCID: PMC4141857.
      Citations: 35     Fields:    Translation:Humans
    39. Dai J, Gu J, Huang M, Eng C, Kopetz ES, Ellis LM, Hawk E, Wu X. GWAS-identified colorectal cancer susceptibility loci associated with clinical outcomes. Carcinogenesis. 2012 Jul; 33(7):1327-31. PMID: 22505654; PMCID: PMC4072910.
      Citations: 30     Fields:    Translation:Humans
    40. Chang J, Dinney CP, Huang M, Wu X, Gu J. Genetic variants in telomere-maintenance genes and bladder cancer risk. PLoS One. 2012; 7(2):e30665. PMID: 22363464; PMCID: PMC3281862.
      Citations: 11     Fields:    Translation:Humans
    41. Lin M, Eng C, Hawk ET, Huang M, Greisinger AJ, Gu J, Ellis LM, Wu X, Lin J. Genetic variants within ultraconserved elements and susceptibility to right- and left-sided colorectal adenocarcinoma. Carcinogenesis. 2012 Apr; 33(4):841-7. PMID: 22318908; PMCID: PMC3324446.
      Citations: 3     Fields:    Translation:HumansCells
    42. Pan JY, Ajani JA, Gu J, Gong Y, Qin A, Quin A, Hung M, Wu X, Izzo JG. Association of Aurora-A (STK15) kinase polymorphisms with clinical outcome of esophageal cancer treated with preoperative chemoradiation. Cancer. 2012 Sep 01; 118(17):4346-53. PMID: 22213102; PMCID: PMC3831524.
      Citations: 14     Fields:    Translation:Humans
    43. Wu X, Scelo G, Purdue MP, Rothman N, Johansson M, Ye Y, Wang Z, Zelenika D, Moore LE, Wood CG, Prokhortchouk E, Gaborieau V, Jacobs KB, Chow WH, Toro JR, Zaridze D, Lin J, Lubinski J, Trubicka J, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Jinga V, Bencko V, Slamova A, Holcatova I, Navratilova M, Janout V, Boffetta P, Colt JS, Davis FG, Schwartz KL, Banks RE, Selby PJ, Harnden P, Berg CD, Hsing AW, Grubb RL, Boeing H, Vineis P, Palli D, Tumino R, Krogh V, Panico S, Duell EJ, Navarro C, Ardanaz E, Dorronsoro M, Khaw KT, Allen NE, Bueno-de-Mesquita HB, Peeters PH, Trichopoulos D, Linseisen J, Overvad K, Romieu I, Riboli E, Stevens VL, Thun MJ, Diver WR, Gapstur SM, Pharoah PD, Easton DF, Albanes D, Virtamo J, Vatten L, Hveem K, Fletcher T, Koppova K, Cussenot O, Cancel-Tassin G, Benhamou S, Hildebrandt MA, Pu X, Foglio M, Lechner D, Hutchinson A, Yeager M, Fraumeni JF, Lathrop M, Skryabin KG, McKay JD, Gu J, Brennan P, Chanock SJ, Clavel-Chapelon F, Quir?s JR, Sanchez MJ, Ljungberg B, Tj?nneland A. A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23. Hum Mol Genet. 2012 Jan 15; 21(2):456-62. PMID: 22010048; PMCID: PMC3276284.
      Citations: 53     Fields:    Translation:HumansCells
    44. Yin J, Lu C, Gu J, Lippman SM, Hildebrandt MA, Lin J, Stewart D, Spitz MR, Wu X. Common genetic variants in cell cycle pathway are associated with survival in stage III-IV non-small-cell lung cancer. Carcinogenesis. 2011 Dec; 32(12):1867-71. PMID: 21965272; PMCID: PMC3220611.
      Citations: 4     Fields:    Translation:Humans
    45. Garcia-Closas M, Ye Y, Rothman N, Figueroa JD, Dinney CP, Chatterjee N, Prokunina-Olsson L, Wang Z, Lin J, Real FX, Jacobs KB, Baris D, Thun M, De Vivo I, Albanes D, Purdue MP, Kogevinas M, Kamat AM, Lerner SP, Grossman HB, Gu J, Pu X, Hutchinson A, Fu YP, Burdett L, Yeager M, Tang W, Serra C, Carrato A, Lloreta J, Johnson A, Schwenn M, Karagas MR, Schned A, Andriole G, Grubb R, Black A, Jacobs EJ, Diver WR, Gapstur SM, Weinstein SJ, Virtamo J, Hunter DJ, Caporaso N, Landi MT, Fraumeni JF, Silverman DT, Chanock SJ, Wu X, Malats N, Tard?n A, Garc?a-Closas R. A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. Hum Mol Genet. 2011 Nov 01; 20(21):4282-9. PMID: 21824976; PMCID: PMC3188994.
      Citations: 51     Fields:    Translation:HumansCells
    46. Xing J, Dinney CP, Shete S, Huang M, Hildebrandt MA, Chen Z, Gu J. Comprehensive pathway-based interrogation of genetic variations in the nucleotide excision DNA repair pathway and risk of bladder cancer. Cancer. 2012 Jan 01; 118(1):205-15. PMID: 21692063; PMCID: PMC3178723.
      Citations: 10     Fields:    Translation:HumansCells
    47. Dai J, Gu J, Lu C, Lin J, Stewart D, Chang D, Roth JA, Wu X. Genetic variations in the regulator of G-protein signaling genes are associated with survival in late-stage non-small cell lung cancer. PLoS One. 2011; 6(6):e21120. PMID: 21698121; PMCID: PMC3117866.
      Citations: 15     Fields:    Translation:HumansCells
    48. Lin M, Stewart DJ, Spitz MR, Hildebrandt MA, Lu C, Lin J, Gu J, Huang M, Lippman SM, Wu X. Genetic variations in the transforming growth factor-beta pathway as predictors of survival in advanced non-small cell lung cancer. Carcinogenesis. 2011 Jul; 32(7):1050-6. PMID: 21515830; PMCID: PMC3128559.
      Citations: 17     Fields:    Translation:Humans
    49. Wu X, Ye Y, Rosell R, Amos CI, Stewart DJ, Hildebrandt MA, Roth JA, Minna JD, Gu J, Lin J, Buch SC, Nukui T, Ramirez Serrano JL, Taron M, Cassidy A, Lu C, Chang JY, Lippman SM, Hong WK, Spitz MR, Romkes M, Yang P. Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy. J Natl Cancer Inst. 2011 May 18; 103(10):817-25. PMID: 21483023; PMCID: PMC3096796.
      Citations: 42     Fields:    Translation:Humans
    50. Gu J, Chen M, Shete S, Amos CI, Kamat A, Ye Y, Lin J, Dinney CP, Wu X. A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer. Cancer Prev Res (Phila). 2011 Apr; 4(4):514-21. PMID: 21460395; PMCID: PMC3076128.
      Citations: 34     Fields:    Translation:HumansCells
    51. Lee JJ, Wu X, Hildebrandt MA, Yang H, Khuri FR, Kim E, Gu J, Ye Y, Lotan R, Spitz MR, Hong WK. Global assessment of genetic variation influencing response to retinoid chemoprevention in head and neck cancer patients. Cancer Prev Res (Phila). 2011 Feb; 4(2):185-93. PMID: 21292633; PMCID: PMC3955084.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    52. Liang D, Meyer L, Chang DW, Lin J, Pu X, Ye Y, Gu J, Wu X, Lu K. Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response. Cancer Res. 2010 Dec 01; 70(23):9765-76. PMID: 21118967; PMCID: PMC5373101.
      Citations: 64     Fields:    Translation:HumansCells
    53. Gu J, Ye Y, Spitz MR, Lin J, Kiemeney LA, Xing J, Hildebrandt MA, Ki Hong W, Amos CI, Wu X. A genetic variant near the PMAIP1/Noxa gene is associated with increased bleomycin sensitivity. Hum Mol Genet. 2011 Feb 15; 20(4):820-6. PMID: 21106707; PMCID: PMC3024041.
      Citations: 5     Fields:    Translation:HumansCells
    54. Masaki K, Ghaffari R, Gu JW, Richardson GP, Freeman DM, Aranyosi AJ. Tectorial membrane material properties in Tecta(Y)(1870C/+) heterozygous mice. Biophys J. 2010 Nov 17; 99(10):3274-81. PMID: 21081075; PMCID: PMC2980748.
      Citations: 8     Fields:    Translation:Animals
    55. Sigurdson AJ, Jones IM, Wei Q, Wu X, Spitz MR, Stram DA, Gross MD, Huang WY, Wang LE, Gu J, Thomas CB, Reding DJ, Hayes RB, Caporaso NE. Prospective analysis of DNA damage and repair markers of lung cancer risk from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Carcinogenesis. 2011 Jan; 32(1):69-73. PMID: 20929901; PMCID: PMC3010173.
      Citations: 13     Fields:    Translation:HumansCells
    56. Gu JW, Halpin CF, Nam EC, Levine RA, Melcher JR. Tinnitus, diminished sound-level tolerance, and elevated auditory activity in humans with clinically normal hearing sensitivity. J Neurophysiol. 2010 Dec; 104(6):3361-70. PMID: 20881196; PMCID: PMC3007631.
      Citations: 117     Fields:    Translation:Humans
    57. Chen M, Hildebrandt MA, Clague J, Kamat AM, Picornell A, Chang J, Zhang X, Izzo J, Yang H, Lin J, Gu J, Chanock S, Kogevinas M, Rothman N, Silverman DT, Garcia-Closas M, Grossman HB, Dinney CP, Wu X, Malats N. Genetic variations in the sonic hedgehog pathway affect clinical outcomes in non-muscle-invasive bladder cancer. Cancer Prev Res (Phila). 2010 Oct; 3(10):1235-45. PMID: 20858759; PMCID: PMC2955764.
      Citations: 28     Fields:    Translation:Humans
    58. Hildebrandt MA, Komaki R, Liao Z, Gu J, Chang JY, Ye Y, Lu C, Stewart DJ, Minna JD, Roth JA, Lippman SM, Cox JD, Hong WK, Spitz MR, Wu X. Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. PLoS One. 2010 Aug 25; 5(8):e12402. PMID: 20811626; PMCID: PMC2928273.
      Citations: 43     Fields:    Translation:HumansPHPublic Health
    59. Hildebrandt MA, Gu J, Lin J, Ye Y, Tan W, Tamboli P, Wood CG, Wu X. Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma. Oncogene. 2010 Oct 21; 29(42):5724-8. PMID: 20676129.
      Citations: 91     Fields:    Translation:HumansCells
    60. Gu J, Ajani JA, Hawk ET, Ye Y, Lee JH, Bhutani MS, Hofstetter WL, Swisher SG, Wang KK, Wu X. Genome-wide catalogue of chromosomal aberrations in barrett's esophagus and esophageal adenocarcinoma: a high-density single nucleotide polymorphism array analysis. Cancer Prev Res (Phila). 2010 Sep; 3(9):1176-86. PMID: 20651033; PMCID: PMC3932797.
      Citations: 45     Fields:    Translation:Humans
    61. Chen M, Gu J, Delclos GL, Killary AM, Fan Z, Hildebrandt MA, Chamberlain RM, Grossman HB, Dinney CP, Wu X. Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients. Carcinogenesis. 2010 Aug; 31(8):1387-91. PMID: 20530239; PMCID: PMC2915631.
      Citations: 29     Fields:    Translation:Humans
    62. Saeki N, Gu J, Yoshida T, Wu X. Prostate stem cell antigen: a Jekyll and Hyde molecule? Clin Cancer Res. 2010 Jul 15; 16(14):3533-8. PMID: 20501618; PMCID: PMC2905486.
      Citations: 76     Fields:    Translation:Humans
    63. Pu X, Hildebrandt MA, Lu C, Lin J, Stewart DJ, Ye Y, Gu J, Spitz MR, Wu X. PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy. Lung Cancer. 2011 Jan; 71(1):82-8. PMID: 20447721; PMCID: PMC2952281.
      Citations: 31     Fields:    Translation:Humans
    64. Chen M, Cassidy A, Gu J, Delclos GL, Zhen F, Yang H, Hildebrandt MA, Lin J, Ye Y, Chamberlain RM, Dinney CP, Wu X. Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk. Carcinogenesis. 2009 Dec; 30(12):2047-52. PMID: 19875696; PMCID: PMC2792319.
      Citations: 38     Fields:    Translation:Humans
    65. Chen M, Ye Y, Yang H, Tamboli P, Matin S, Tannir NM, Wood CG, Gu J, Wu X. Genome-wide profiling of chromosomal alterations in renal cell carcinoma using high-density single nucleotide polymorphism arrays. Int J Cancer. 2009 Nov 15; 125(10):2342-8. PMID: 19521957; PMCID: PMC2768265.
      Citations: 38     Fields:    Translation:HumansCells
    66. Reyes-Gibby CC, Spitz MR, Yennurajalingam S, Swartz M, Gu J, Wu X, Bruera E, Shete S. Role of inflammation gene polymorphisms on pain severity in lung cancer patients. Cancer Epidemiol Biomarkers Prev. 2009 Oct; 18(10):2636-42. PMID: 19773451; PMCID: PMC2759856.
      Citations: 27     Fields:    Translation:Humans
    67. Yang H, Gu J, Wang KK, Zhang W, Xing J, Chen Z, Ajani JA, Wu X. MicroRNA expression signatures in Barrett's esophagus and esophageal adenocarcinoma. Clin Cancer Res. 2009 Sep 15; 15(18):5744-52. PMID: 19737949; PMCID: PMC2745487.
      Citations: 68     Fields:    Translation:Humans
    68. Wu X, Ye Y, Kiemeney LA, Sulem P, Rafnar T, Matullo G, Seminara D, Yoshida T, Saeki N, Andrew AS, Dinney CP, Czerniak B, Zhang ZF, Kiltie AE, Bishop DT, Vineis P, Porru S, Buntinx F, Kellen E, Zeegers MP, Kumar R, Rudnai P, Gurzau E, Koppova K, Mayordomo JI, Sanchez M, Saez B, Lindblom A, de Verdier P, Steineck G, Mills GB, Schned A, Guarrera S, Polidoro S, Chang SC, Lin J, Chang DW, Hale KS, Majewski T, Grossman HB, Thorlacius S, Thorsteinsdottir U, Aben KK, Witjes JA, Stefansson K, Amos CI, Karagas MR, Gu J. Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat Genet. 2009 Sep; 41(9):991-5. PMID: 19648920; PMCID: PMC3313685.
      Citations: 122     Fields:    Translation:HumansCells
    69. Wu X, Spitz MR, Lee JJ, Lippman SM, Ye Y, Yang H, Khuri FR, Kim E, Gu J, Lotan R, Hong WK. Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants. Cancer Prev Res (Phila). 2009 Jul; 2(7):617-24. PMID: 19584075; PMCID: PMC2964280.
      Citations: 39     Fields:    Translation:Humans
    70. Hildebrandt MA, Gu J, Wu X. Pharmacogenomics of platinum-based chemotherapy in NSCLC. Expert Opin Drug Metab Toxicol. 2009 Jul; 5(7):745-55. PMID: 19442035; PMCID: PMC3417337.
      Citations: 31     Fields:    Translation:HumansAnimals
    71. Lin J, Kamat A, Gu J, Chen M, Dinney CP, Forman MR, Wu X. Dietary intake of vegetables and fruits and the modification effects of GSTM1 and NAT2 genotypes on bladder cancer risk. Cancer Epidemiol Biomarkers Prev. 2009 Jul; 18(7):2090-7. PMID: 19549811.
      Citations: 20     Fields:    Translation:HumansAnimals
    72. Masaki K, Gu JW, Ghaffari R, Chan G, Smith RJ, Freeman DM, Aranyosi AJ. Col11a2 deletion reveals the molecular basis for tectorial membrane mechanical anisotropy. Biophys J. 2009 Jun 03; 96(11):4717-24. PMID: 19486694; PMCID: PMC2711449.
      Citations: 14     Fields:    Translation:Animals
    73. Xing J, Ajani JA, Chen M, Izzo J, Lin J, Chen Z, Gu J, Wu X. Constitutive short telomere length of chromosome 17p and 12q but not 11q and 2p is associated with an increased risk for esophageal cancer. Cancer Prev Res (Phila). 2009 May; 2(5):459-65. PMID: 19401529; PMCID: PMC2701666.
      Citations: 37     Fields:    Translation:HumansCells
    74. Horikawa Y, Wood CG, Yang H, Zhao H, Ye Y, Gu J, Lin J, Habuchi T, Wu X. Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. Clin Cancer Res. 2008 Dec 01; 14(23):7956-62. PMID: 19047128; PMCID: PMC2650498.
      Citations: 115     Fields:    Translation:Humans
    75. Wu X, Ros MM, Gu J, Kiemeney L. Epidemiology and genetic susceptibility to bladder cancer. BJU Int. 2008 Nov; 102(9 Pt B):1207-15. PMID: 19035883.
      Citations: 18     Fields:    Translation:HumansPHPublic Health
    76. Ye Y, Wang KK, Gu J, Yang H, Lin J, Ajani JA, Wu X. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. Cancer Prev Res (Phila). 2008 Nov; 1(6):460-9. PMID: 19138993; PMCID: PMC2768267.
      Citations: 114     Fields:    Translation:Humans
    77. Wu X, Lu C, Ye Y, Chang J, Yang H, Lin J, Gu J, Hong WK, Stewart D, Spitz MR. Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy. Pharmacogenet Genomics. 2008 Nov; 18(11):955-65. PMID: 18854777; PMCID: PMC2665725.
      Citations: 21     Fields:    Translation:HumansCells
    78. Gu J, Horikawa Y, Chen M, Dinney CP, Wu X. Benzo(a)pyrene diol epoxide-induced chromosome 9p21 aberrations are associated with increased risk of bladder cancer. Cancer Epidemiol Biomarkers Prev. 2008 Sep; 17(9):2445-50. PMID: 18768515.
      Citations: 6     Fields:    Translation:HumansCells
    79. Horikawa Y, Gu J, Wu X. Genetic susceptibility to bladder cancer with an emphasis on gene-gene and gene-environmental interactions. Curr Opin Urol. 2008 Sep; 18(5):493-8. PMID: 18670273.
      Citations: 9     Fields:    Translation:Humans
    80. Xing J, Chen M, Wood CG, Lin J, Spitz MR, Ma J, Amos CI, Shields PG, Benowitz NL, Gu J, de Andrade M, Swan GE, Wu X. Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst. 2008 Aug 06; 100(15):1104-12. PMID: 18664653; PMCID: PMC2720693.
      Citations: 119     Fields:    Translation:HumansCells
    81. Xing J, Wu X, Vaporciyan AA, Spitz MR, Gu J. Prognostic significance of ataxia-telangiectasia mutated, DNA-dependent protein kinase catalytic subunit, and Ku heterodimeric regulatory complex 86-kD subunit expression in patients with nonsmall cell lung cancer. Cancer. 2008 Jun 15; 112(12):2756-64. PMID: 18457328; PMCID: PMC3384998.
      Citations: 29     Fields:    Translation:HumansCells
    82. Ye Y, Yang H, Grossman HB, Dinney C, Wu X, Gu J. Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer. Cancer. 2008 Jun; 112(11):2467-74. PMID: 18361427.
      Citations: 28     Fields:    Translation:Humans
    83. Gu JW, Hemmert W, Freeman DM, Aranyosi AJ. Frequency-dependent shear impedance of the tectorial membrane. Biophys J. 2008 Sep; 95(5):2529-38. PMID: 18515382; PMCID: PMC2517030.
      Citations: 21     Fields:    Translation:Animals
    84. Xing J, Stewart DJ, Gu J, Lu C, Spitz MR, Wu X. Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer. Br J Cancer. 2008 May 20; 98(10):1716-22. PMID: 18414412; PMCID: PMC2391117.
      Citations: 18     Fields:    Translation:HumansCells
    85. Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RS. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet. 2008 May; 40(5):616-22. PMID: 18385676; PMCID: PMC2713680.
      Citations: 671     Fields:    Translation:HumansCells
    86. Yang H, Gu J, Lin X, Grossman HB, Ye Y, Dinney CP, Wu X. Profiling of genetic variations in inflammation pathway genes in relation to bladder cancer predisposition. Clin Cancer Res. 2008 Apr 01; 14(7):2236-44. PMID: 18381966.
      Citations: 26     Fields:    Translation:Humans
    87. Wu X, Lin J, Grossman HB, Huang M, Gu J, Etzel CJ, Amos CI, Dinney CP, Spitz MR. Projecting individualized probabilities of developing bladder cancer in white individuals. J Clin Oncol. 2007 Nov 01; 25(31):4974-81. PMID: 17971596.
      Citations: 32     Fields:    Translation:Humans
    88. Zhu Y, Yang H, Chen Q, Lin J, Grossman HB, Dinney CP, Wu X, Gu J. Modulation of DNA damage/DNA repair capacity by XPC polymorphisms. DNA Repair (Amst). 2008 Feb 01; 7(2):141-8. PMID: 17923445; PMCID: PMC2254649.
      Citations: 27     Fields:    Translation:HumansCells
    89. Lin J, Swan GE, Shields PG, Benowitz NL, Gu J, Amos CI, de Andrade M, Spitz MR, Wu X. Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2065-71. PMID: 17932354.
      Citations: 24     Fields:    Translation:HumansCells
    90. Saldivar JS, Lu KH, Liang D, Gu J, Huang M, Vlastos AT, Follen M, Wu X. Moving toward individualized therapy based on NER polymorphisms that predict platinum sensitivity in ovarian cancer patients. Gynecol Oncol. 2007 Oct; 107(1 Suppl 1):S223-9. PMID: 17825393.
      Citations: 12     Fields:    Translation:HumansCells
    91. Chen M, Kamat AM, Huang M, Grossman HB, Dinney CP, Lerner SP, Wu X, Gu J. High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk. Carcinogenesis. 2007 Oct; 28(10):2160-5. PMID: 17728339.
      Citations: 29     Fields:    Translation:HumansCells
    92. Engels EA, Wu X, Gu J, Dong Q, Liu J, Spitz MR. Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer. Cancer Res. 2007 Jul 01; 67(13):6520-7. PMID: 17596594.
      Citations: 77     Fields:    Translation:Humans
    93. Milam MR, Gu J, Yang H, Celestino J, Wu W, Horwitz IB, Lacour RA, Westin SN, Gershenson DM, Wu X, Lu KH. STK15 F31I polymorphism is associated with increased uterine cancer risk: a pilot study. Gynecol Oncol. 2007 Oct; 107(1):71-4. PMID: 17599395.
      Citations: 12     Fields:    Translation:Humans
    94. Kader AK, Liu J, Shao L, Dinney CP, Lin J, Wang Y, Gu J, Grossman HB, Wu X. Matrix metalloproteinase polymorphisms are associated with bladder cancer invasiveness. Clin Cancer Res. 2007 May 01; 13(9):2614-20. PMID: 17473191.
      Citations: 24     Fields:    Translation:HumansCells
    95. Wu X, Gu J, Spitz MR. Mutagen sensitivity: a genetic predisposition factor for cancer. Cancer Res. 2007 Apr 15; 67(8):3493-5. PMID: 17440053.
      Citations: 31     Fields:    Translation:Humans
    96. Chen M, Gu J, Xing J, Spitz MR, Wu X. Irradiation-induced telomerase activity and the risk of lung cancer: a pilot case-control study. Cancer. 2007 Mar 15; 109(6):1157-63. PMID: 17265522.
      Citations: 2     Fields:    Translation:HumansCells
    97. Wu X, Lin X, Dinney CP, Gu J, Grossman HB. Genetic polymorphism in bladder cancer. Front Biosci. 2007 Jan 01; 12:192-213. PMID: 17127293.
      Citations: 10     Fields:    Translation:HumansCells
    98. Kader AK, Shao L, Dinney CP, Schabath MB, Wang Y, Liu J, Gu J, Grossman HB, Wu X. Matrix metalloproteinase polymorphisms and bladder cancer risk. Cancer Res. 2006 Dec 15; 66(24):11644-8. PMID: 17178858.
      Citations: 35     Fields:    Translation:Humans
    99. Gu J, Berman D, Lu C, Wistuba II, Roth JA, Frazier M, Spitz MR, Wu X. Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer. Clin Cancer Res. 2006 Dec 15; 12(24):7329-38. PMID: 17189404.
      Citations: 34     Fields:    Translation:HumansCells
    100. Wu X, Gu J, Dong Q, Huang M, Do KA, Hong WK, Spitz MR. Joint effect of mutagen sensitivity and insulin-like growth factors in predicting the risk of developing secondary primary tumors and tumor recurrence in patients with head and neck cancer. Clin Cancer Res. 2006 Dec 01; 12(23):7194-201. PMID: 17145846.
      Citations: 8     Fields:    Translation:HumansCells
    101. Lin X, Gu J, Lu C, Spitz MR, Wu X. Expression of telomere-associated genes as prognostic markers for overall survival in patients with non-small cell lung cancer. Clin Cancer Res. 2006 Oct 01; 12(19):5720-5. PMID: 17020976.
      Citations: 19     Fields:    Translation:HumansCells
    102. Gu J, Gong Y, Huang M, Lu C, Spitz MR, Wu X. Polymorphisms of STK15 (Aurora-A) gene and lung cancer risk in Caucasians. Carcinogenesis. 2007 Feb; 28(2):350-5. PMID: 16926177.
      Citations: 21     Fields:    Translation:HumansCells
    103. Wu X, Gu J, Wu TT, Swisher SG, Liao Z, Correa AM, Liu J, Etzel CJ, Amos CI, Huang M, Chiang SS, Milas L, Hittelman WN, Ajani JA. Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer. J Clin Oncol. 2006 Aug 10; 24(23):3789-98. PMID: 16785472.
      Citations: 62     Fields:    Translation:Humans
    104. Wu X, Spitz MR, Amos CI, Lin J, Shao L, Gu J, de Andrade M, Benowitz NL, Shields PG, Swan GE. Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res. 2006 Jun 15; 66(12):5993-6. PMID: 16778168.
      Citations: 28     Fields:    Translation:HumansCells
    105. Gu J, Wu X, Dong Q, Romeo MJ, Lin X, Gutkind JS, Berman DM. A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican Americans. Cancer. 2006 Jun 15; 106(12):2716-24. PMID: 16691626.
      Citations: 10     Fields:    Translation:HumansCells
    106. Huang M, Spitz MR, Gu J, Lee JJ, Lin J, Lippman SM, Wu X. Cyclin D1 gene polymorphism as a risk factor for oral premalignant lesions. Carcinogenesis. 2006 Oct; 27(10):2034-7. PMID: 16638786.
      Citations: 22     Fields:    Translation:Humans
    107. Wu X, Gu J, Grossman HB, Amos CI, Etzel C, Huang M, Zhang Q, Millikan RE, Lerner S, Dinney CP, Spitz MR. Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes. Am J Hum Genet. 2006 Mar; 78(3):464-79. PMID: 16465622; PMCID: PMC1380289.
      Citations: 124     Fields:    Translation:HumansCells
    108. Schabath MB, Wu X, Wei Q, Li G, Gu J, Spitz MR. Combined effects of the p53 and p73 polymorphisms on lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Jan; 15(1):158-61. PMID: 16434604.
      Citations: 16     Fields:    Translation:Humans
    109. Gu J, Grossman HB, Dinney CP, Wu X. The pharmacogenetic impact of inflammatory genes on bladder cancer recurrence. Pharmacogenomics. 2005 Sep; 6(6):575-84. PMID: 16142998.
      Citations: 8     Fields:    Translation:Humans
    110. Leibovici D, Grossman HB, Dinney CP, Millikan RE, Lerner S, Wang Y, Gu J, Dong Q, Wu X. Polymorphisms in inflammation genes and bladder cancer: from initiation to recurrence, progression, and survival. J Clin Oncol. 2005 Aug 20; 23(24):5746-56. PMID: 16110031.
      Citations: 57     Fields:    Translation:Humans
    111. Gu J, Spitz MR, Zhao H, Lin J, Grossman HB, Dinney CP, Wu X. Roles of tumor suppressor and telomere maintenance genes in cancer and aging--an epidemiological study. Carcinogenesis. 2005 Oct; 26(10):1741-7. PMID: 15905204.
      Citations: 8     Fields:    Translation:HumansCells
    112. Gu J, Zhao H, Dinney CP, Zhu Y, Leibovici D, Bermejo CE, Grossman HB, Wu X. Nucleotide excision repair gene polymorphisms and recurrence after treatment for superficial bladder cancer. Clin Cancer Res. 2005 Feb 15; 11(4):1408-15. PMID: 15746040.
      Citations: 36     Fields:    Translation:HumansCells
    113. Gu J, Liang D, Wang Y, Lu C, Wu X. Effects of N-acetyl transferase 1 and 2 polymorphisms on bladder cancer risk in Caucasians. Mutat Res. 2005 Mar 07; 581(1-2):97-104. PMID: 15725609.
      Citations: 29     Fields:    Translation:HumansCells
    114. Gu J, Zhang L, Swisher SG, Liu J, Roth JA, Fang B. Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis. Oncogene. 2004 Feb 12; 23(6):1300-7. PMID: 14676844.
      Citations: 7     Fields:    Translation:HumansCells
    115. Wu S, Zhu H, Gu J, Zhang L, Teraishi F, Davis JJ, Jacob DA, Fang B. Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol. Cancer Res. 2004 Feb 01; 64(3):1110-3. PMID: 14871845.
      Citations: 14     Fields:    Translation:HumansCells
    116. Lin T, Gu J, Zhang L, Davis JJ, Huang X, Cabbini G, Ji L, Fang B. Enhancing adenovirus-mediated gene transfer in vitro and in vivo by addition of protamine and hydrocortisone. J Gene Med. 2003 Oct; 5(10):868-875. PMID: 14533195.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    117. Lin T, Zhang L, Davis J, Gu J, Nishizaki M, Ji L, Roth JA, Xiong M, Fang B. Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers. Mol Ther. 2003 Sep; 8(3):441-8. PMID: 12946317.
      Citations: 14     Fields:    Translation:Humans
    118. Gu J, Fang B. Telomerase promoter-driven cancer gene therapy. Cancer Biol Ther. 2003 Jul-Aug; 2(4 Suppl 1):S64-70. PMID: 14508082.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    119. Huang X, Lin T, Gu J, Zhang L, Roth JA, Liu J, Fang B. Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene. Int J Oncol. 2003 Jun; 22(6):1241-5. PMID: 12738989.
      Citations: 12     Fields:    Translation:HumansCells
    120. Swisher SG, Roth JA, Komaki R, Gu J, Lee JJ, Hicks M, Ro JY, Hong WK, Merritt JA, Ahrar K, Atkinson NE, Correa AM, Dolormente M, Dreiling L, El-Naggar AK, Fossella F, Francisco R, Glisson B, Grammer S, Herbst R, Huaringa A, Kemp B, Khuri FR, Kurie JM, Liao Z, McDonnell TJ, Morice R, Morello F, Munden R, Papadimitrakopoulou V, Pisters KM, Putnam JB, Sarabia AJ, Shelton T, Stevens C, Shin DM, Smythe WR, Vaporciyan AA, Walsh GL, Yin M. Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy. Clin Cancer Res. 2003 Jan; 9(1):93-101. PMID: 12538456.
      Citations: 47     Fields:    Translation:HumansCellsCTClinical Trials
    121. Lin T, Huang X, Gu J, Zhang L, Roth JA, Xiong M, Curley SA, Yu Y, Hunt KK, Fang B. Long-term tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells. Oncogene. 2002 Nov 14; 21(52):8020-8. PMID: 12439752.
      Citations: 26     Fields:    Translation:HumansCells
    122. Huang X, Lin T, Gu J, Zhang L, Roth JA, Stephens LC, Yu Y, Liu J, Fang B. Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft. Gene Ther. 2002 Oct; 9(20):1379-86. PMID: 12365003.
      Citations: 11     Fields:    Translation:HumansAnimals
    123. Zhang L, Gu J, Lin T, Huang X, Roth JA, Fang B. Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line. Gene Ther. 2002 Sep; 9(18):1262-70. PMID: 12215894.
      Citations: 16     Fields:    Translation:HumansCells
    124. Pirocanac EC, Nassirpour R, Yang M, Wang J, Nardin SR, Gu J, Fang B, Moossa AR, Hoffman RM, Bouvet M. Bax-induction gene therapy of pancreatic cancer. J Surg Res. 2002 Aug; 106(2):346-51. PMID: 12175991.
      Citations: 17     Fields:    Translation:HumansCells
    125. Gu J, Zhang L, Huang X, Lin T, Yin M, Xu K, Ji L, Roth JA, Fang B. A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo. Oncogene. 2002 Jul 18; 21(31):4757-64. PMID: 12101414.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    126. Lin T, Gu J, Zhang L, Huang X, Stephens LC, Curley SA, Fang B. Targeted expression of green fluorescent protein/tumor necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumor activity without toxic effects on primary human hepatocytes. Cancer Res. 2002 Jul 01; 62(13):3620-5. PMID: 12097263.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    127. Tanyi JL, Lapushin R, Eder A, Auersperg N, Tabassam FH, Roth JA, Gu J, Fang B, Mills GB, Wolf J. Identification of tissue- and cancer-selective promoters for the introduction of genes into human ovarian cancer cells. Gynecol Oncol. 2002 Jun; 85(3):451-8. PMID: 12051873.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    128. Gu J, Andreeff M, Roth JA, Fang B. hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity. Gene Ther. 2002 Jan; 9(1):30-7. PMID: 11850720.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    129. Kagawa S, Gu J, Honda T, McDonnell TJ, Swisher SG, Roth JA, Fang B. Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death. Clin Cancer Res. 2001 May; 7(5):1474-80. PMID: 11350920.
      Citations: 44     Fields:    Translation:HumansCells
    130. Kagawa S, He C, Gu J, Koch P, Rha SJ, Roth JA, Curley SA, Stephens LC, Fang B. Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene. Cancer Res. 2001 Apr 15; 61(8):3330-8. PMID: 11309289.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    131. Koch PE, Guo ZS, Kagawa S, Gu J, Roth JA, Fang B. Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system. Mol Ther. 2001 Mar; 3(3):278-83. PMID: 11273768.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    132. Gu J, Kagawa S, Takakura M, Kyo S, Inoue M, Roth JA, Fang B. Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers. Cancer Res. 2000 Oct 01; 60(19):5359-64. PMID: 11034071.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    133. Perumal K, Gu J, Reddy R. Evolutionary conservation of post-transcriptional 3' end adenylation of small RNAs: S. cerevisiae signal recognition particle RNA and U2 small nuclear RNA are post-transcriptionally adenylated. Mol Cell Biochem. 2000 May; 208(1-2):99-109. PMID: 10939633.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    134. Kagawa S, Gu J, Swisher SG, Ji L, Roth JA, Lai D, Stephens LC, Fang B. Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines. Cancer Res. 2000 Mar 01; 60(5):1157-61. PMID: 10728665.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    135. Chen Y, Sinha K, Perumal K, Gu J, Reddy R. Accurate 3' end processing and adenylation of human signal recognition particle RNA and alu RNA in vitro. J Biol Chem. 1998 Dec 25; 273(52):35023-31. PMID: 9857035.
      Citations: 17     Fields:    Translation:HumansCells
    136. Gu J, Shimba S, Nomura N, Reddy R. Isolation and characterization of a new 110 kDa human nuclear RNA-binding protein (p110nrb). Biochim Biophys Acta. 1998 Jul 30; 1399(1):1-9. PMID: 9714707.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    137. Sinha KM, Gu J, Chen Y, Reddy R. Adenylation of small RNAs in human cells. Development of a cell-free system for accurate adenylation on the 3'-end of human signal recognition particle RNA. J Biol Chem. 1998 Mar 20; 273(12):6853-9. PMID: 9506988.
      Citations: 22     Fields:    Translation:HumansCells
    138. Gu J, Chen Y, Reddy R. Small RNA database. Nucleic Acids Res. 1998 Jan 01; 26(1):160-2. PMID: 9399823; PMCID: PMC147212.
      Citations: 7     Fields:    Translation:HumansAnimals
    139. Gu J, Shumyatsky G, Makan N, Reddy R. Formation of 2',3'-cyclic phosphates at the 3' end of human U6 small nuclear RNA in vitro. Identification of 2',3'-cyclic phosphates at the 3' ends of human signal recognition particle and mitochondrial RNA processing RNAs. J Biol Chem. 1997 Aug 29; 272(35):21989-93. PMID: 9268336.
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