TitleAssociate Professor
InstitutionMD Anderson
DepartmentPalliative Care & Rehabilitation Medicine
Address1515 Holcombe Blvd.
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xu T, Chakraborty S, Wei D, Tran M, Rhea R, Wei B, Nguyen P, Gagea M, Cohen L, Liao Z, Yang P, Xu T, Chakraborty S, Wei D, Tran M, Rhea R, Wei B, Nguyen P, Gagea M, Cohen L, Liao Z, Yang P. Evaluation of the Protective Effect of Compound Kushen Injection Against Radiation- induced Pneumonitis in Mice. Res Sq. 2024 Jan 30. PMID: 38352564; PMCID: PMC10862984.
    2. Wei D, Chen D, Mou H, Chakraborty S, Wei B, Tan L, Lorenzi PL, Qian X, Yang P. Targeting Glutamine Metabolism with a Novel Na+/K+-ATPase Inhibitor RX108 in Hepatocellular Carcinoma. Mol Cancer Ther. 2023 06 01; 22(6):693-705. PMID: 36780187.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Wei D, Wang L, Liu Y, Hafley MA, Tan L, Lorenzi PL, Yang P, Zuo X, Bresalier RS. Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression. Dig Dis Sci. 2023 07; 68(7):3043-3058. PMID: 37071246.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Narayanan S, de Mores AR, Cohen L, Anwar MM, Lazar F, Hicklen R, Lopez G, Yang P, Bruera E. Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Curr Oncol Rep. 2023 06; 25(6):569-587. PMID: 36995535.
      Citations:    Fields:    Translation:HumansAnimals
    5. Gunther JR, Chadha AS, Guha S, Raju GS, Maru DM, Munsell MF, Jiang Y, Yang P, Felix E, Clemons M, Mathew GG, Singh PK, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Eng C, Delclos ME, Crane CH, Das P, Krishnan S. A phase II randomized double blinded trial evaluating the efficacy of curcumin with pre-operative chemoradiation for rectal cancer. J Gastrointest Oncol. 2022 Dec; 13(6):2938-2950. PMID: 36636059; PMCID: PMC9830363.
      Citations: 2     
    6. Yang P, Zuo X, Advani S, Wei B, Malek J, Day RS, Shureiqi I. Celecoxib Colorectal Bioavailability and Chemopreventive Response in Patients with Familial Adenomatous Polyposis. Cancer Prev Res (Phila). 2022 04 01; 15(4):217-223. PMID: 34610992; PMCID: PMC8980107.
      Citations:    Fields:    Translation:Humans
    7. Bui D, Yin T, Duan S, Wei B, Yang P, Wong SJ, You M, Singh R, Hu M. Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer. J Nat Prod. 2021 09 24; 84(9):2486-2495. PMID: 34463097; PMCID: PMC10607708.
      Citations:    Fields:    Translation:AnimalsCells
    8. Cata JP, Lacagnina MJ, Li J, Gorur A, Agudelo-Jimenez R, Wei B, Hagberg CA, Dougherty PM, Shureiqi I, Yang P, Grace PM, Pati?o M. A rat model to investigate quality of recovery after abdominal surgery. Pain Rep. 2021 Jul-Aug; 6(2):e943. PMID: 34235345; PMCID: PMC8253582.
      Citations: 1     
    9. Davis JS, Kanikarla-Marie P, Gagea M, Yu PL, Fang D, Sebastian M, Yang P, Hawk E, Dashwood R, Lichtenberger LM, Menter D, Kopetz S. Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development. BMC Cancer. 2020 Sep 10; 20(1):871. PMID: 32912193; PMCID: PMC7488444.
      Citations: 2     Fields:    Translation:HumansAnimals
    10. Liu F, Zuo X, Liu Y, Deguchi Y, Moussalli MJ, Chen W, Yang P, Wei B, Tan L, Lorenzi PL, Gao S, Jaoude JC, Mehdizadeh A, Valentin LA, Wei D, Shureiqi I. Suppression of Membranous LRP5 Recycling, Wnt/?-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P. Cell Rep. 2020 08 18; 32(7):108049. PMID: 32814052; PMCID: PMC8765570.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    11. Ravoori MK, Singh S, Yang P, Wei W, Chen H, Ma J, Bankson JA, Kundra V. In vivo magnetic resonance imaging of orthotopic prostate cancer. Biotechniques. 2020 07; 69(1):395-403. PMID: 32363906.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    12. Yang P, Rhea PR, Conway T, Nookala S, Hegde V, Gagea M, Ajami NJ, Harribance SL, Ochoa J, Sastry JK, Cohen L. Human Biofield Therapy Modulates Tumor Microenvironment and Cancer Stemness in Mouse Lung Carcinoma. Integr Cancer Ther. 2020 Jan-Dec; 19:1534735420940398. PMID: 32975128; PMCID: PMC7522816.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    13. Garcia MK, Meng Z, Rosenthal DI, Shen Y, Chambers M, Yang P, Wei Q, Hu C, Wu C, Bei W, Prinsloo S, Chiang J, Lopez G, Cohen L. Effect of True and Sham Acupuncture on Radiation-Induced Xerostomia Among Patients With Head and Neck Cancer: A Randomized Clinical Trial. JAMA Netw Open. 2019 12 02; 2(12):e1916910. PMID: 31808921; PMCID: PMC6902763.
      Citations: 9     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    14. Yang P, Jiang Y, Pan Y, Ding X, Rhea P, Ding J, Hawke DH, Felsher D, Narla G, Lu Z, Lee RT. Mistletoe extract Fraxini inhibits the proliferation of liver cancer by down-regulating c-Myc expression. Sci Rep. 2019 04 23; 9(1):6428. PMID: 31015523; PMCID: PMC6478697.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    15. Yang P, Jiang Y, Rhea PR, Coway T, Chen D, Gagea M, Harribance SL, Cohen L. Human Biofield Therapy and the Growth of Mouse Lung Carcinoma. Integr Cancer Ther. 2019 Jan-Dec; 18:1534735419840797. PMID: 30947564; PMCID: PMC6475842.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    16. Torres-Adorno AM, Vitrac H, Qi Y, Tan L, Levental KR, Fan YY, Yang P, Chapkin RS, Eckhardt BL, Ueno NT. Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux. Oncogene. 2019 03; 38(12):2135-2150. PMID: 30459358; PMCID: PMC6430703.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    17. Umamaheswaran S, Dasari SK, Yang P, Lutgendorf SK, Sood AK. Stress, inflammation, and eicosanoids: an emerging perspective. Cancer Metastasis Rev. 2018 09; 37(2-3):203-211. PMID: 29948328; PMCID: PMC6237279.
      Citations: 26     Fields:    Translation:HumansAnimals
    18. Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W. Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy. Cell Metab. 2018 May 01; 27(5):977-987.e4. PMID: 29628419; PMCID: PMC5932208.
      Citations: 183     Fields:    Translation:HumansAnimalsCells
    19. Wang Y, Guo YR, Liu K, Yin Z, Liu R, Xia Y, Tan L, Yang P, Lee JH, Li XJ, Hawke D, Zheng Y, Qian X, Lyu J, He J, Xing D, Tao YJ, Lu Z. KAT2A coupled with the a-KGDH complex acts as a histone H3 succinyltransferase. Nature. 2017 12 14; 552(7684):273-277. PMID: 29211711; PMCID: PMC5841452.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    20. Wang X, Reyes ME, Zhang D, Funakoshi Y, Trape AP, Gong Y, Kogawa T, Eckhardt BL, Masuda H, Pirman DA, Yang P, Reuben JM, Woodward WA, Bartholomeusz C, Hortobagyi GN, Tripathy D, Ueno NT. EGFR signaling promotes inflammation and cancer stem-like activity in inflammatory breast cancer. Oncotarget. 2017 Sep 15; 8(40):67904-67917. PMID: 28978083; PMCID: PMC5620223.
      Citations: 17     Fields:    
    21. Arun B, Austin T, Babiera GV, Basen-Engquist K, Carmack CL, Chaoul A, Cohen L, Connelly L, Haddad R, Harrison C, Li Y, Mallaiah S, Nagarathna R, Parker PA, Perkins GH, Reuben JM, Shih YT, Spelman A, Sood A, Yang P, Yeung SJ. A Comprehensive Lifestyle Randomized Clinical Trial: Design and Initial Patient Experience. Integr Cancer Ther. 2017 03; 16(1):3-20. PMID: 27903842; PMCID: PMC5558265.
      Citations: 9     Fields:    Translation:Humans
    22. Kim SH, Hashimoto Y, Cho SN, Roszik J, Dal F, Kim SF, Menter DG, Yang P, Ekmekcioglu S, Grimm EA, Milton DR. Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression. Pigment Cell Melanoma Res. 2016 May; 29(3):297-308. PMID: 26801201; PMCID: PMC4840087.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    23. Jiang Y, Pan Y, Rhea PR, Tan L, Gagea M, Cohen L, Fischer SM, Yang P. A Sucrose-Enriched Diet Promotes Tumorigenesis in Mammary Gland in Part through the 12-Lipoxygenase Pathway. Cancer Res. 2016 Jan 01; 76(1):24-9. PMID: 26729790; PMCID: PMC4703949.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    24. Pan Y, Jiang Y, Tan L, Ravoori MK, Gagea M, Kundra V, Fischer SM, Yang P. Deletion of cyclooxygenase-2 inhibits K-ras-induced lung carcinogenesis. Oncotarget. 2015 Nov 17; 6(36):38816-26. PMID: 26452035; PMCID: PMC4770739.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    25. McCarroll RE, Rubinstein AE, Kingsley CV, Yang J, Yang P, Court LE. 3D-Printed Small-Animal Immobilizer for Use in Preclinical Radiotherapy. J Am Assoc Lab Anim Sci. 2015 Sep; 54(5):545-8. PMID: 26424253; PMCID: PMC4587623.
      Citations: 9     Fields:    Translation:Animals
    26. Efuet ET, Ding XP, Cartwright C, Pan Y, Cohen L, Yang P. Huachansu mediates cell death in non-Hodgkin's lymphoma by induction of caspase-3 and inhibition of MAP kinase. Int J Oncol. 2015 Aug; 47(2):592-600. PMID: 26062471; PMCID: PMC6904102.
      Citations: 5     Fields:    Translation:HumansCells
    27. Lee RT, Yang P, Greenlee H, Bauer-Wu S, Balneaves LG, Zick S. Personalized integrative oncology: targeted approaches for optimal outcomes: the 11th International Conference of the Society for Integrative Oncology. Integr Cancer Ther. 2015 Jan; 14(1):98-105. PMID: 25505022.
      Citations: 1     Fields:    Translation:HumansAnimals
    28. Pan Y, Rhea P, Tan L, Cartwright C, Lee HJ, Ravoori MK, Addington C, Gagea M, Kundra V, Kim SJ, Newman RA, Yang P. PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. Invest New Drugs. 2015 Apr; 33(2):271-9. PMID: 25476893; PMCID: PMC4387257.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    29. Kim SH, Margalit O, Katoh H, Wang D, Wu H, Xia D, Holla VR, Yang P, DuBois RN. CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models. Invest New Drugs. 2014 Dec; 32(6):1105-1112. PMID: 25085205; PMCID: PMC4356209.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    30. Hong DS, Henary H, Falchook GS, Naing A, Fu S, Moulder S, Wheler JJ, Tsimberidou A, Durand JB, Khan R, Yang P, Johansen M, Newman RA, Kurzrock R. First-in-human study of pbi-05204, an oleander-derived inhibitor of akt, fgf-2, nf-?? and p70s6k, in patients with advanced solid tumors. Invest New Drugs. 2014 Dec; 32(6):1204-12. PMID: 24919855.
      Citations: 27     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    31. Yang P, Jiang Y, Fischer SM. Prostaglandin E3 metabolism and cancer. Cancer Lett. 2014 Jun 28; 348(1-2):1-11. PMID: 24657656; PMCID: PMC4366418.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    32. Van Kanegan MJ, He DN, Dunn DE, Yang P, Newman RA, West AE, Lo DC. BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin. J Neurosci. 2014 Jan 15; 34(3):963-8. PMID: 24431454; PMCID: PMC3891971.
      Citations: 21     Fields:    Translation:Animals
    33. Brewer TM, Masuda H, Liu DD, Shen Y, Liu P, Iwamoto T, Kai K, Barnett CM, Woodward WA, Reuben JM, Yang P, Hortobagyi GN, Ueno NT. Statin use in primary inflammatory breast cancer: a cohort study. Br J Cancer. 2013 Jul 23; 109(2):318-24. PMID: 23820253; PMCID: PMC3721387.
      Citations: 40     Fields:    Translation:Humans
    34. Pirman DA, Efuet E, Ding XP, Pan Y, Tan L, Fischer SM, DuBois RN, Yang P. Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry. PLoS One. 2013; 8(4):e61379. PMID: 23658609; PMCID: PMC3637300.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    35. Charo C, Holla V, Arumugam T, Hwang R, Yang P, Dubois RN, Menter DG, Logsdon CD, Ramachandran V. Prostaglandin E2 regulates pancreatic stellate cell activity via the EP4 receptor. Pancreas. 2013 Apr; 42(3):467-74. PMID: 23090667; PMCID: PMC3600062.
      Citations: 21     Fields:    Translation:HumansCells
    36. Yang P, Cartwright C, Chan D, Ding J, Felix E, Pan Y, Pang J, Rhea P, Block K, Fischer SM, Newman RA. Anticancer activity of fish oils against human lung cancer is associated with changes in formation of PGE2 and PGE3 and alteration of Akt phosphorylation. Mol Carcinog. 2014 Jul; 53(7):566-77. PMID: 23371504; PMCID: PMC4395033.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    37. Garcia MK, McQuade J, Haddad R, Patel S, Lee R, Yang P, Palmer JL, Cohen L. Systematic review of acupuncture in cancer care: a synthesis of the evidence. J Clin Oncol. 2013 Mar 01; 31(7):952-60. PMID: 23341529; PMCID: PMC3577953.
      Citations: 78     Fields:    Translation:Humans
    38. Singh S, Shenoy S, Nehete PN, Yang P, Nehete B, Fontenot D, Yang G, Newman RA, Sastry KJ. Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity. Fitoterapia. 2013 Jan; 84:32-9. PMID: 23127567.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    39. Yang P, Cartwright C, Efuet E, Hamilton SR, Wistuba II, Menter D, Addington C, Shureiqi I, Newman RA. Cellular location and expression of Na+, K+ -ATPase a subunits affect the anti-proliferative activity of oleandrin. Mol Carcinog. 2014 Apr; 53(4):253-63. PMID: 23073998; PMCID: PMC4442617.
      Citations: 14     Fields:    Translation:HumansCells
    40. Yang P, Cartwright CA, Li J, Wen S, Prokhorova IN, Shureiqi I, Troncoso P, Navone NM, Newman RA, Kim J. Arachidonic acid metabolism in human prostate cancer. Int J Oncol. 2012 Oct; 41(4):1495-503. PMID: 22895552; PMCID: PMC3982713.
      Citations: 24     Fields:    Translation:HumansCells
    41. Meng Z, Garrett CR, Shen Y, Liu L, Yang P, Huo Y, Zhao Q, Spelman AR, Ng CS, Chang DZ, Cohen L. Prospective randomised evaluation of traditional Chinese medicine combined with chemotherapy: a randomised phase II study of wild toad extract plus gemcitabine in patients with advanced pancreatic adenocarcinomas. Br J Cancer. 2012 Jul 24; 107(3):411-6. PMID: 22782343; PMCID: PMC3405220.
      Citations: 38     Fields:    Translation:HumansAnimalsCTClinical Trials
    42. Subbaramaiah K, Howe LR, Zhou XK, Yang P, Hudis CA, Kopelovich L, Dannenberg AJ. Pioglitazone, a PPAR? agonist, suppresses CYP19 transcription: evidence for involvement of 15-hydroxyprostaglandin dehydrogenase and BRCA1. Cancer Prev Res (Phila). 2012 Oct; 5(10):1183-94. PMID: 22787115; PMCID: PMC3694442.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    43. Fan YY, Monk JM, Hou TY, Callway E, Vincent L, Weeks B, Yang P, Chapkin RS. Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model. J Lipid Res. 2012 Jul; 53(7):1287-95. PMID: 22534642; PMCID: PMC3371240.
      Citations: 40     Fields:    Translation:Animals
    44. Menter DG, Ramsauer VP, Harirforoosh S, Chakraborty K, Yang P, Hsi L, Newman RA, Krishnan K. Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites. PLoS One. 2011; 6(12):e28813. PMID: 22216116; PMCID: PMC3245236.
      Citations: 29     Fields:    Translation:HumansCells
    45. Dunn DE, He DN, Yang P, Johansen M, Newman RA, Lo DC. In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models. J Neurochem. 2011 Nov; 119(4):805-14. PMID: 21950737.
      Citations: 23     Fields:    Translation:Animals
    46. Ban K, Sprunt JM, Martin S, Yang P, Kozar RA. Glutamine activates peroxisome proliferator-activated receptor-? in intestinal epithelial cells via 15-S-HETE and 13-OXO-ODE: a novel mechanism. Am J Physiol Gastrointest Liver Physiol. 2011 Sep; 301(3):G547-54. PMID: 21737777; PMCID: PMC3174542.
      Citations: 7     Fields:    Translation:AnimalsCells
    47. Couroucli XI, Liang YH, Jiang W, Wang L, Barrios R, Yang P, Moorthy B. Prenatal administration of the cytochrome P4501A inducer, ?-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants. Toxicol Appl Pharmacol. 2011 Oct 15; 256(2):83-94. PMID: 21745492; PMCID: PMC3196339.
      Citations: 30     Fields:    Translation:HumansAnimals
    48. Wang L, Raju U, Milas L, Molkentine D, Zhang Z, Yang P, Cohen L, Meng Z, Liao Z. Huachansu, containing cardiac glycosides, enhances radiosensitivity of human lung cancer cells. Anticancer Res. 2011 Jun; 31(6):2141-8. PMID: 21737634.
      Citations: 14     Fields:    Translation:HumansCells
    49. Gao Y, Li HX, Xu LT, Wang P, Xu LY, Cohen L, Yang PY, Gu K, Meng ZQ. Bufalin enhances the anti-proliferative effect of sorafenib on human hepatocellular carcinoma cells through downregulation of ERK. Mol Biol Rep. 2012 Feb; 39(2):1683-9. PMID: 21617941.
      Citations: 8     Fields:    Translation:HumansCells
    50. Subbaramaiah K, Howe LR, Bhardwaj P, Du B, Gravaghi C, Yantiss RK, Zhou XK, Blaho VA, Hla T, Yang P, Kopelovich L, Hudis CA, Dannenberg AJ. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prev Res (Phila). 2011 Mar; 4(3):329-46. PMID: 21372033; PMCID: PMC3071249.
      Citations: 193     Fields:    Translation:HumansAnimalsCells
    51. Campbell SE, Rudder B, Phillips RB, Whaley SG, Stimmel JB, Leesnitzer LM, Lightner J, Dessus-Babus S, Duffourc M, Stone WL, Menter DG, Newman RA, Yang P, Aggarwal BB, Krishnan K. ?-Tocotrienol induces growth arrest through a novel pathway with TGF?2 in prostate cancer. Free Radic Biol Med. 2011 May 15; 50(10):1344-54. PMID: 21335085.
      Citations: 12     Fields:    Translation:HumansCells
    52. Li H, Wang P, Gao Y, Zhu X, Liu L, Cohen L, Meng Z, Yang P. Na+/K+-ATPase a3 mediates sensitivity of hepatocellular carcinoma cells to bufalin. Oncol Rep. 2011 Mar; 25(3):825-30. PMID: 21181095.
      Citations: 17     Fields:    Translation:HumansCells
    53. Koh GY, McCutcheon K, Zhang F, Liu D, Cartwright CA, Martin R, Yang P, Liu Z. Improvement of obesity phenotype by Chinese sweet leaf tea (Rubus suavissimus) components in high-fat diet-induced obese rats. J Agric Food Chem. 2011 Jan 12; 59(1):98-104. PMID: 21138267.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    54. Shureiqi I, Chen D, Day RS, Zuo X, Hochman FL, Ross WA, Cole RA, Moy O, Morris JS, Xiao L, Newman RA, Yang P, Lippman SM. Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. Cancer Prev Res (Phila). 2010 Jul; 3(7):829-38. PMID: 20570882; PMCID: PMC2900425.
      Citations: 32     Fields:    Translation:Humans
    55. Suraneni MV, Schneider-Broussard R, Moore JR, Davis TC, Maldonado CJ, Li H, Newman RA, Kusewitt D, Hu J, Yang P, Tang DG. Transgenic expression of 15-lipoxygenase 2 (15-LOX2) in mouse prostate leads to hyperplasia and cell senescence. Oncogene. 2010 Jul 29; 29(30):4261-75. PMID: 20514017; PMCID: PMC3042242.
      Citations: 25     Fields:    Translation:Animals
    56. Frenkel M, Mishra BM, Sen S, Yang P, Pawlus A, Vence L, Leblanc A, Cohen L, Banerji P, Banerji P. Cytotoxic effects of ultra-diluted remedies on breast cancer cells. Int J Oncol. 2010 Feb; 36(2):395-403. PMID: 20043074.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    57. Meng Z, Yang P, Shen Y, Bei W, Zhang Y, Ge Y, Newman RA, Cohen L, Liu L, Thornton B, Chang DZ, Liao Z, Kurzrock R. Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer. Cancer. 2009 Nov 15; 115(22):5309-18. PMID: 19701908; PMCID: PMC2856335.
      Citations: 84     Fields:    Translation:HumansCTClinical Trials
    58. Lee CW, Rickman B, Rogers AB, Muthupalani S, Takaishi S, Yang P, Wang TC, Fox JG. Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice. Cancer Res. 2009 Oct 15; 69(20):8166-74. PMID: 19826057; PMCID: PMC2766772.
      Citations: 29     Fields:    Translation:AnimalsCells
    59. Khan GN, Gorin MA, Rosenthal D, Pan Q, Bao LW, Wu ZF, Newman RA, Pawlus AD, Yang P, Lansky EP, Merajver SD. Pomegranate fruit extract impairs invasion and motility in human breast cancer. Integr Cancer Ther. 2009 Sep; 8(3):242-53. PMID: 19815594.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    60. Yang P, Menter DG, Cartwright C, Chan D, Dixon S, Suraokar M, Mendoza G, Llansa N, Newman RA. Oleandrin-mediated inhibition of human tumor cell proliferation: importance of Na,K-ATPase alpha subunits as drug targets. Mol Cancer Ther. 2009 Aug; 8(8):2319-28. PMID: 19671733.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    61. Miyaki A, Yang P, Tai HH, Subbaramaiah K, Dannenberg AJ. Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes. Am J Physiol Gastrointest Liver Physiol. 2009 Sep; 297(3):G559-66. PMID: 19608733; PMCID: PMC2739822.
      Citations: 10     Fields:    Translation:HumansCells
    62. Yan M, Myung SJ, Fink SP, Lawrence E, Lutterbaugh J, Yang P, Zhou X, Liu D, Rerko RM, Willis J, Dawson D, Tai HH, Barnholtz-Sloan JS, Newman RA, Bertagnolli MM, Markowitz SD. 15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9409-13. PMID: 19470469; PMCID: PMC2695050.
      Citations: 54     Fields:    Translation:HumansAnimals
    63. Campbell SE, Musich PR, Whaley SG, Stimmel JB, Leesnitzer LM, Dessus-Babus S, Duffourc M, Stone W, Newman RA, Yang P, Krishnan K. Gamma tocopherol upregulates the expression of 15-S-HETE and induces growth arrest through a PPAR gamma-dependent mechanism in PC-3 human prostate cancer cells. Nutr Cancer. 2009; 61(5):649-62. PMID: 19838939.
      Citations: 15     Fields:    Translation:HumansCells
    64. Hughes D, Otani T, Yang P, Newman RA, Yantiss RK, Altorki NK, Port JL, Yan M, Markowitz SD, Mazumdar M, Tai HH, Subbaramaiah K, Dannenberg AJ. NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer. Cancer Prev Res (Phila). 2008 Sep; 1(4):241-9. PMID: 19138967; PMCID: PMC2720569.
      Citations: 22     Fields:    Translation:HumansAnimals
    65. Yang P, Sun Z, Chan D, Cartwright CA, Vijjeswarapu M, Ding J, Chen X, Newman RA. Zyflamend reduces LTB4 formation and prevents oral carcinogenesis in a 7,12-dimethylbenz[alpha]anthracene (DMBA)-induced hamster cheek pouch model. Carcinogenesis. 2008 Nov; 29(11):2182-9. PMID: 18687669; PMCID: PMC3697064.
      Citations: 12     Fields:    Translation:AnimalsCells
    66. Brown PH, Subbaramaiah K, Salmon AP, Baker R, Newman RA, Yang P, Zhou XK, Bissonnette RP, Dannenberg AJ, Howe LR. Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid. Cancer Prev Res (Phila). 2008 Aug; 1(3):208-14. PMID: 19138958; PMCID: PMC2612594.
      Citations: 11     Fields:    Translation:AnimalsCells
    67. Jia Q, Lupton JR, Smith R, Weeks BR, Callaway E, Davidson LA, Kim W, Fan YY, Yang P, Newman RA, Kang JX, McMurray DN, Chapkin RS. Reduced colitis-associated colon cancer in Fat-1 (n-3 fatty acid desaturase) transgenic mice. Cancer Res. 2008 May 15; 68(10):3985-91. PMID: 18483285; PMCID: PMC2648804.
      Citations: 76     Fields:    Translation:AnimalsCells
    68. Holla VR, Backlund MG, Yang P, Newman RA, DuBois RN. Regulation of prostaglandin transporters in colorectal neoplasia. Cancer Prev Res (Phila). 2008 Jul; 1(2):93-9. PMID: 19138942.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    69. Newman RA, Yang P, Pawlus AD, Block KI. Cardiac glycosides as novel cancer therapeutic agents. Mol Interv. 2008 Feb; 8(1):36-49. PMID: 18332483.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
    70. Newman RA, Kondo Y, Yokoyama T, Dixon S, Cartwright C, Chan D, Johansen M, Yang P. Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside. Integr Cancer Ther. 2007 Dec; 6(4):354-64. PMID: 18048883.
      Citations: 48     Fields:    Translation:HumansCells
    71. Vanamala J, Glagolenko A, Yang P, Carroll RJ, Murphy ME, Newman RA, Ford JR, Braby LA, Chapkin RS, Turner ND, Lupton JR. Dietary fish oil and pectin enhance colonocyte apoptosis in part through suppression of PPARdelta/PGE2 and elevation of PGE3. Carcinogenesis. 2008 Apr; 29(4):790-6. PMID: 18024478; PMCID: PMC2659531.
      Citations: 49     Fields:    Translation:Animals
    72. Sun Z, Sood S, Li N, Yang P, Newman RA, Yang CS, Chen X. Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases. Oral Oncol. 2008 Jul; 44(7):652-7. PMID: 17936675; PMCID: PMC2546572.
      Citations: 4     Fields:    Translation:HumansAnimals
    73. Wang X, Colby JK, Yang P, Fischer SM, Newman RA, Klein RD. The resistance to the tumor suppressive effects of COX inhibitors and COX-2 gene disruption in TRAMP mice is associated with the loss of COX expression in prostate tissue. Carcinogenesis. 2008 Jan; 29(1):120-8. PMID: 17942462.
      Citations: 2     Fields:    Translation:Animals
    74. Freedman RS, Wang E, Voiculescu S, Patenia R, Bassett RL, Deavers M, Marincola FM, Yang P, Newman RA. Comparative analysis of peritoneum and tumor eicosanoids and pathways in advanced ovarian cancer. Clin Cancer Res. 2007 Oct 01; 13(19):5736-44. PMID: 17908963.
      Citations: 17     Fields:    Translation:Humans
    75. Yang P, Cartwright C, Chan D, Vijjeswarapu M, Ding J, Newman RA. Zyflamend-mediated inhibition of human prostate cancer PC3 cell proliferation: effects on 12-LOX and Rb protein phosphorylation. Cancer Biol Ther. 2007 Feb; 6(2):228-36. PMID: 17218785.
      Citations: 9     Fields:    Translation:HumansCells
    76. Schroeder CP, Yang P, Newman RA, Lotan R. Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines. J Exp Ther Oncol. 2007; 6(3):183-92. PMID: 17552358.
      Citations: 10     Fields:    Translation:HumansCells
    77. Yang P, Chan D, Felix E, Madden T, Klein RD, Shureiqi I, Chen X, Dannenberg AJ, Newman RA. Determination of endogenous tissue inflammation profiles by LC/MS/MS: COX- and LOX-derived bioactive lipids. Prostaglandins Leukot Essent Fatty Acids. 2006 Dec; 75(6):385-95. PMID: 17011176.
      Citations: 36     Fields:    Translation:HumansAnimals
    78. Subbarayan V, Krieg P, Hsi LC, Kim J, Yang P, Sabichi AL, Llansa N, Mendoza G, Logothetis CJ, Newman RA, Lippman SM, Menter DG. 15-Lipoxygenase-2 gene regulation by its product 15-(S)-hydroxyeicosatetraenoic acid through a negative feedback mechanism that involves peroxisome proliferator-activated receptor gamma. Oncogene. 2006 Sep 28; 25(44):6015-25. PMID: 16682954.
      Citations: 9     Fields:    Translation:HumansCells
    79. Sun Z, Sood S, Li N, Ramji D, Yang P, Newman RA, Yang CS, Chen X. Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors. Carcinogenesis. 2006 Sep; 27(9):1902-8. PMID: 16632477.
      Citations: 21     Fields:    Translation:Animals
    80. Newman RA, Yang P, Hittelman WN, Lu T, Ho DH, Ni D, Chan D, Vijjeswarapu M, Cartwright C, Dixon S, Felix E, Addington C. Oleandrin-mediated oxidative stress in human melanoma cells. J Exp Ther Oncol. 2006; 5(3):167-81. PMID: 16528968.
      Citations: 28     Fields:    Translation:HumansCells
    81. Shureiqi I, Wu Y, Chen D, Yang XL, Guan B, Morris JS, Yang P, Newman RA, Broaddus R, Hamilton SR, Lynch P, Levin B, Fischer SM, Lippman SM. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. Cancer Res. 2005 Dec 15; 65(24):11486-92. PMID: 16357157; PMCID: PMC1564070.
      Citations: 39     Fields:    Translation:HumansCells
    82. Howe LR, Chang SH, Tolle KC, Dillon R, Young LJ, Cardiff RD, Newman RA, Yang P, Thaler HT, Muller WJ, Hudis C, Brown AM, Hla T, Subbaramaiah K, Dannenberg AJ. HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice. Cancer Res. 2005 Nov 01; 65(21):10113-9. PMID: 16267038.
      Citations: 55     Fields:    Translation:Animals
    83. Deguchi A, Xing SW, Shureiqi I, Yang P, Newman RA, Lippman SM, Feinmark SJ, Oehlen B, Weinstein IB. Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells. Cancer Res. 2005 Sep 15; 65(18):8442-7. PMID: 16166323.
      Citations: 17     Fields:    Translation:HumansCells
    84. Kim J, Yang P, Suraokar M, Sabichi AL, Llansa ND, Mendoza G, Subbarayan V, Logothetis CJ, Newman RA, Lippman SM, Menter DG. Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived products. Cancer Res. 2005 Jul 15; 65(14):6189-98. PMID: 16024620.
      Citations: 27     Fields:    Translation:HumansCells
    85. Bhatia B, Tang S, Yang P, Doll A, Newman RA, Tang DG, Aum?eller G. Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells. Oncogene. 2005 May 19; 24(22):3583-95. PMID: 15750631.
      Citations: 17     Fields:    Translation:HumansCells
    86. Patel MI, Subbaramaiah K, Du B, Chang M, Yang P, Newman RA, Cordon-Cardo C, Thaler HT, Dannenberg AJ. Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism. Clin Cancer Res. 2005 Mar 01; 11(5):1999-2007. PMID: 15756026.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    87. Subbarayan V, Xu XC, Kim J, Yang P, Hoque A, Sabichi AL, Llansa N, Mendoza G, Logothetis CJ, Newman RA, Lippman SM, Menter DG. Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia. Neoplasia. 2005 Mar; 7(3):280-93. PMID: 15799828; PMCID: PMC1501140.
      Citations: 20     Fields:    Translation:HumansCells
    88. Kim E, Rundhaug JE, Benavides F, Yang P, Newman RA, Fischer SM. An antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis. Oncogene. 2005 Feb 10; 24(7):1174-87. PMID: 15558016.
      Citations: 10     Fields:    Translation:AnimalsCells
    89. Wright KC, Yang P, Van Pelt CS, Hicks ME, Collin P, Newman RA. Evaluation of targeted arterial delivery of the branched chain fatty acid 12-methyltetradecanoic acid as a novel therapy for solid tumors. J Exp Ther Oncol. 2005; 5(1):55-68. PMID: 16416602.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    90. Johnson FM, Yang P, Newman RA, Donato NJ. Cyclooxygenase-2 induction and prostaglandin E2 accumulation in squamous cell carcinoma as a consequence of epidermal growth factor receptor activation by imatinib mesylate. J Exp Ther Oncol. 2004 Dec; 4(4):317-25. PMID: 15844661.
      Citations: 3     Fields:    Translation:HumansCells
    91. Schroeder CP, Yang P, Newman RA, Lotan R. Eicosanoid metabolism in squamous cell carcinoma cell lines derived from primary and metastatic head and neck cancer and its modulation by celecoxib. Cancer Biol Ther. 2004 Sep; 3(9):847-52. PMID: 15254428.
      Citations: 9     Fields:    Translation:HumansCells
    92. Yang P, Chan D, Felix E, Cartwright C, Menter DG, Madden T, Klein RD, Fischer SM, Newman RA. Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells. J Lipid Res. 2004 Jun; 45(6):1030-9. PMID: 14993240.
      Citations: 43     Fields:    Translation:HumansCells
    93. Yang P, Collin P, Madden T, Chan D, Sweeney-Gotsch B, McConkey D, Newman RA. Inhibition of proliferation of PC3 cells by the branched-chain fatty acid, 12-methyltetradecanoic acid, is associated with inhibition of 5-lipoxygenase. Prostate. 2003 Jun 01; 55(4):281-91. PMID: 12712407.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    94. Bhatia B, Maldonado CJ, Tang S, Chandra D, Klein RD, Chopra D, Shappell SB, Yang P, Newman RA, Tang DG. Subcellular localization and tumor-suppressive functions of 15-lipoxygenase 2 (15-LOX2) and its splice variants. J Biol Chem. 2003 Jul 04; 278(27):25091-100. PMID: 12704195.
      Citations: 29     Fields:    Translation:HumansCells
    95. Chen X, Li N, Wang S, Hong J, Fang M, Yousselfson J, Yang P, Newman RA, Lubet RA, Yang CS. Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. Carcinogenesis. 2002 Dec; 23(12):2095-102. PMID: 12507933.
      Citations: 20     Fields:    Translation:Animals
    96. Raju U, Nakata E, Yang P, Newman RA, Ang KK, Milas L. In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: mechanistic considerations. Int J Radiat Oncol Biol Phys. 2002 Nov 01; 54(3):886-94. PMID: 12377342.
      Citations: 18     Fields:    Translation:AnimalsCells
    97. Thuillier P, Brash AR, Kehrer JP, Stimmel JB, Leesnitzer LM, Yang P, Newman RA, Fischer SM. Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors. Biochem J. 2002 Sep 15; 366(Pt 3):901-10. PMID: 12069687; PMCID: PMC1222830.
      Citations: 14     Fields:    Translation:AnimalsCells
    98. Yang P, Felix E, Madden T, Fischer SM, Newman RA. Quantitative high-performance liquid chromatography/electrospray ionization tandem mass spectrometric analysis of 2- and 3-series prostaglandins in cultured tumor cells. Anal Biochem. 2002 Sep 01; 308(1):168-77. PMID: 12234478.
      Citations: 27     Fields:    Translation:HumansCells
    99. Tang S, Bhatia B, Maldonado CJ, Yang P, Newman RA, Liu J, Chandra D, Traag J, Klein RD, Fischer SM, Chopra D, Shen J, Zhau HE, Chung LW, Tang DG. Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem. 2002 May 03; 277(18):16189-201. PMID: 11839751.
      Citations: 41     Fields:    Translation:HumansCells
    100. Kempen EC, Yang P, Felix E, Madden T, Newman RA. Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. Anal Biochem. 2001 Oct 15; 297(2):183-90. PMID: 11673886.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    101. Shureiqi I, Chen D, Lotan R, Yang P, Newman RA, Fischer SM, Lippman SM. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer Res. 2000 Dec 15; 60(24):6846-50. PMID: 11156377.
      Citations: 41     Fields:    Translation:HumansCells
    102. Shureiqi I, Chen D, Lee JJ, Yang P, Newman RA, Brenner DE, Lotan R, Fischer SM, Lippman SM. 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst. 2000 Jul 19; 92(14):1136-42. PMID: 10904086.
      Citations: 50     Fields:    Translation:HumansCells
    103. St Pyrek J, Aggarval SK, Barboza P, Goodman JP, Yang PY. Metabolites of nuatigenin ((22S,25S)22,25-epoxy-3 beta, 26-dihydroxy-furost-5-ene) accumulate in the bile of rabbits fed oats. Adv Exp Med Biol. 1996; 404:443-58. PMID: 8957313.
      Citations:    Fields:    Translation:Animals
    104. A sucrose-enriched diet promotes tumorigenesis in mammary gland in part through the 12-lipoxygenase pathway. Cancer Research. 76:24-29.
    105. PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. Investigational New Drugs.
    106. A practical synthesis and X-ray crystallographic analysis of dithymoquinone, a photodimer of thymoquinone. Letters in Organic Chemistry. 9:762-766.
    107. CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models. Investigational New Drugs.
    108. Journal of Herbal Pharmacotherapy. 1:1-16.
    109. A new model to study the role of arachidonic acid in colon cancer pathophysiology. Cancer Prevention Research. 9:750-757.
    110. Deletion of cyclooxygenase-2 inhibits K-ras-induced lung carcinogenesis. Oncotarget. 6:38816-38826.
    111. Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke. Scientific Reports. 6.
    112. Huachansu mediates cell death in non-Hodgkin's lymphoma by induction of caspase-3 and inhibition of MAP kinase. International Journal of Oncology. 47:592-600.
    113. Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. Oncogene.
    114. Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression. Pigment Cell and Melanoma Research.
    115. Omega-3-acid ethyl esters block the protumorigenic effects of obesity in mouse models of postmenopausal basal-like and claudin-low breast cancer. Cancer Prevention Research. 8:796-806.
    116. Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial. Genomics Data. 6:154-158.
    117. Na+/K++-ATPase a1 subunit, a novel therapeutic target for hepatocellular carcinoma. Oncotarget. 6:28183-28193.
    118. 3D-printed small-animal immobilizer for use in preclinical radiotherapy. Journal of the American Association for Laboratory Animal Science. 54:545-548.
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