-
Hou H, Carns J, Schwarz RA, Gillenwater AM, Anandasabapathy S, Richards-Kortum RR. Use of topical methylene blue to image nuclear morphometry with a low-cost scanning darkfield microendoscope. J Biomed Opt. 2024 May; 29(5):050501.
PMID: 38774711; PMCID: PMC11107336.
Citations: Fields:
Translation:
HumansAnimalsCells
-
Gillenwater AM, Vigneswaran N, Sikora AG. Assessing the Role of Inflammation in Oral Tongue Carcinogenesis. J Clin Oncol. 2024 May 20; 42(15):1729-1730.
PMID: 38635939.
Citations: Fields:
Translation:
Humans
-
Jin L, Tang Y, Coole JB, Tan MT, Zhao X, Badaoui H, Robinson JT, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR, Veeraraghavan A. DeepDOF-SE: affordable deep-learning microscopy platform for slide-free histology. Nat Commun. 2024 Apr 05; 15(1):2935.
PMID: 38580633; PMCID: PMC10997797.
-
Mansour J, Nesbitt B, Khanjae S, Horowitz G, Amit M, Muhanna N, Hofstede TM, Gillenwater A. The Feasibility and Outcome of Integra? Bilayer Matrix in the Reconstruction of Oral Cavity Defects. Otolaryngol Head Neck Surg. 2024 Feb; 170(2):373-379.
PMID: 37717219.
Citations: Fields:
Translation:
Humans
-
Hou H, Tang Y, Coole JB, Kortum A, Schwarz RA, Carns J, Gillenwater AM, Ramalingam P, Milbourne A, Salcedo MP, Schmeler KM, Richards-Kortum RR. Scanning darkfield high-resolution microendoscope for label-free microvascular imaging. Biomed Opt Express. 2023 Oct 01; 14(10):5097-5112.
PMID: 37854554; PMCID: PMC10581811.
Citations:
-
Coole JB, Brenes D, Mitbander R, Vohra I, Hou H, Kortum A, Tang Y, Maker Y, Schwarz RA, Carns J, Badaoui H, Williams M, Vigneswaran N, Gillenwater A, Richards-Kortum R. Multimodal optical imaging with real-time projection of cancer risk and biopsy guidance maps for early oral cancer diagnosis and treatment. J Biomed Opt. 2023 01; 28(1):016002.
PMID: 36654656; PMCID: PMC9838568.
Citations: Fields:
Translation:
Humans
-
William WN, Zhang J, Zhao X, Parra ER, Uraoka N, Lin HY, Peng SA, El-Naggar AK, Rodriguez-Canales J, Song J, Gillenwater AM, Wistuba II, Myers JN, Gold KA, Ferrarotto R, Hwu P, Davoli T, Lee JJ, Heymach JV, Papadimitrakopoulou VA, Lippman SM. Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort. Cancer. 2023 03 01; 129(5):714-727.
PMID: 36597662; PMCID: PMC10508302.
Citations: Fields:
Translation:
HumansCells
-
Brenes DR, Nipper AJ, Tan MT, Gleber-Netto FO, Schwarz RA, Pickering CR, Williams MD, Vigneswaran N, Gillenwater AM, Sikora AG, Richards-Kortum RR. Mildly dysplastic oral lesions with optically-detectable abnormalities share genetic similarities with severely dysplastic lesions. Oral Oncol. 2022 12; 135:106232.
PMID: 36335817; PMCID: PMC9881670.
Citations: Fields:
Translation:
HumansCells
-
Bouvard V, Nethan ST, Singh D, Warnakulasuriya S, Mehrotra R, Chaturvedi AK, Chen TH, Ayo-Yusuf OA, Gupta PC, Kerr AR, Tilakaratne WM, Anantharaman D, Conway DI, Gillenwater A, Johnson NW, Kowalski LP, Leon ME, Mandrik O, Nagao T, Prasad VM, Ramadas K, Roitberg F, Saintigny P, Sankaranarayanan R, Santos-Silva AR, Sinha DN, Vatanasapt P, Zain RB, Lauby-Secretan B. IARC Perspective on Oral Cancer Prevention. N Engl J Med. 2022 11 24; 387(21):1999-2005.
PMID: 36378601.
Citations:
6 Fields:
Translation:
Humans
-
Wise-Draper TM, Gulati S, Palackdharry S, Hinrichs BH, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Patil Y, Riaz MK, Tang A, Mark J, Zender C, Gillenwater AM, Bell D, Kurtzweil N, Mathews M, Allen CL, Mierzwa ML, Casper K, Jandarov R, Medvedovic M, Lee JJ, Harun N, Takiar V, Gillison M. Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2022 04 01; 28(7):1345-1352.
PMID: 35338369; PMCID: PMC8976828.
Citations: Fields:
Translation:
HumansCTClinical Trials
-
Contrera KJ, Chinn SB, Weber RS, Roberts D, Myers JN, Lai SY, Lewis CM, Hessel AC, Gillenwater AM, Mulcahy CF, Yu P, Hanasono MM, Fuller CD, Chambers MS, Zafereo ME. Outcomes after definitive surgery for mandibular osteoradionecrosis. Head Neck. 2022 06; 44(6):1313-1323.
PMID: 35238096; PMCID: PMC9081223.
Citations: Fields:
Translation:
Humans
-
Cognetti DM, Johnson JM, Curry JM, Kochuparambil ST, McDonald D, Mott F, Fidler MJ, Stenson K, Vasan NR, Razaq MA, Campana J, Ha P, Mann G, Ishida K, Garcia-Guzman M, Biel M, Gillenwater AM. Phase 1/2a, open-label, multicenter study of RM-1929 photoimmunotherapy in patients with locoregional, recurrent head and neck squamous cell carcinoma. Head Neck. 2021 12; 43(12):3875-3887.
PMID: 34626024; PMCID: PMC9293150.
Citations:
9 Fields:
Translation:
HumansCTClinical Trials
-
Dahlstrom KR, Anderson KS, Guo M, Kwon MC, Messick CA, Pettaway CA, Asomaning N, Hopper M, Price A, Xu L, Day AT, Gillenwater AM, Sturgis EM. Screening for HPV-related oropharyngeal, anal, and penile cancers in middle-aged men: Initial report from the HOUSTON clinical trial. Oral Oncol. 2021 09; 120:105397.
PMID: 34182223.
Citations: Fields:
Translation:
HumansCells
-
Abdelmeguid AS, Silver NL, Boonsripitayanon M, Glisson BS, Ferrarotto R, Gunn GB, Phan J, Gillenwater AM, Hanna EY. Role of induction chemotherapy for oral cavity squamous cell carcinoma. Cancer. 2021 09 01; 127(17):3107-3112.
PMID: 33909292.
Citations: Fields:
Translation:
Humans
-
Sweeney KJ, Tetzlaff MT, Vega F, Gillenwater A, Zuo Z, Gross N, Nagarajan P, Wargo J, Nelson K, Prieto VG, Torres-Cabala CA, Curry JL. Tertiary lymphoid structures with overlapping histopathologic features of cutaneous marginal zone lymphoma during neoadjuvant cemiplimab therapy are associated with antitumor response. J Cutan Pathol. 2021 May; 48(5):674-679.
PMID: 33399228.
Citations: Fields:
Translation:
HumansCells
-
Jin L, Tang Y, Wu Y, Coole JB, Tan MT, Zhao X, Badaoui H, Robinson JT, Williams MD, Gillenwater AM, Richards-Kortum RR, Veeraraghavan A. Deep learning extended depth-of-field microscope for fast and slide-free histology. Proc Natl Acad Sci U S A. 2020 12 29; 117(52):33051-33060.
PMID: 33318169; PMCID: PMC7776814.
Citations:
7 Fields:
Translation:
HumansAnimals
-
Yang EC, Brenes DR, Vohra IS, Schwarz RA, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR. Algorithm to quantify nuclear features and confidence intervals for classification of oral neoplasia from high-resolution optical images. J Med Imaging (Bellingham). 2020 Sep; 7(5):054502.
PMID: 32999894; PMCID: PMC7503985.
Citations:
-
Tan MT, Wu JG, Callejas-Valera JL, Schwarz RA, Gillenwater AM, Richards-Kortum RR, Vigneswaran N. A PIK3CA transgenic mouse model with chemical carcinogen exposure mimics human oral tongue tumorigenesis. Int J Exp Pathol. 2020 02; 101(1-2):45-54.
PMID: 32436348; PMCID: PMC7306900.
Citations:
3 Fields:
Translation:
AnimalsCells
-
Yang EC, Vohra IS, Badaoui H, Schwarz RA, Cherry KD, Jacob J, Rodriguez J, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR. Prospective evaluation of oral premalignant lesions using a multimodal imaging system: a pilot study. Head Neck. 2020 02; 42(2):171-179.
PMID: 31621979; PMCID: PMC7003735.
Citations:
4 Fields:
Translation:
Humans
-
Cherry KD, Schwarz RA, Yang EC, Vohra IS, Badaoui H, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum R. Autofluorescence Imaging to Monitor the Progression of Oral Potentially Malignant Disorders. Cancer Prev Res (Phila). 2019 11; 12(11):791-800.
PMID: 31451520; PMCID: PMC7319038.
Citations:
3 Fields:
Translation:
Humans
-
Yang EC, Vohra IS, Badaoui H, Schwarz RA, Cherry KD, Quang T, Jacob J, Lang A, Bass N, Rodriguez J, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR. Development of an integrated multimodal optical imaging system with real-time image analysis for the evaluation of oral premalignant lesions. J Biomed Opt. 2019 02; 24(2):1-10.
PMID: 30793567; PMCID: PMC6383051.
Citations:
8 Fields:
Translation:
Humans
-
Truong AT, Truong DT, Gillenwater AM, Soliz JM, Rahlfs TF. Securing the Airway in Pretracheal Dermal Metastases From Oropharyngeal Carcinoma: A Case Report. A A Pract. 2018 Oct 15; 11(8):221-223.
PMID: 29688927.
Citations: Fields:
Translation:
Humans
-
Yang EC, Schwarz RA, Lang AK, Bass N, Badaoui H, Vohra IS, Cherry KD, Williams MD, Gillenwater AM, Vigneswaran N, Richards-Kortum RR. In Vivo Multimodal Optical Imaging: Improved Detection of Oral Dysplasia in Low-Risk Oral Mucosal Lesions. Cancer Prev Res (Phila). 2018 08; 11(8):465-476.
PMID: 29903741; PMCID: PMC6082417.
Citations:
9 Fields:
Translation:
HumansCTClinical Trials
-
Yang EC, Tan MT, Schwarz RA, Richards-Kortum RR, Gillenwater AM, Vigneswaran N. Noninvasive diagnostic adjuncts for the evaluation of potentially premalignant oral epithelial lesions: current limitations and future directions. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 06; 125(6):670-681.
PMID: 29631985; PMCID: PMC6083875.
Citations:
21 Fields:
Translation:
Humans
-
Mays AC, Gillenwater AM, Garvey PB. Rare presentation of heterotopic ossification along a fibula free flap pedicle in a high-volume microvascular reconstruction practice. Head Neck. 2018 03; 40(3):E21-E24.
PMID: 29272061.
Citations:
3 Fields:
Translation:
Humans
-
Quang T, Tran EQ, Schwarz RA, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum R. Prospective Evaluation of Multimodal Optical Imaging with Automated Image Analysis to Detect Oral Neoplasia In Vivo. Cancer Prev Res (Phila). 2017 Oct; 10(10):563-570.
PMID: 28765195; PMCID: PMC5626620.
Citations:
12 Fields:
Translation:
Humans
-
Quinlan-Davidson SR, Mohamed ASR, Myers JN, Gunn GB, Johnson FM, Skinner H, Beadle BM, Gillenwater AM, Phan J, Frank SJ, William WN, Wong AJ, Lai SY, Fuller CD, Morrison WH, Rosenthal DI, Garden AS. Outcomes of oral cavity cancer patients treated with surgery followed by postoperative intensity modulated radiation therapy. Oral Oncol. 2017 09; 72:90-97.
PMID: 28797467; PMCID: PMC5796661.
Citations:
7 Fields:
Translation:
Humans
-
Shadfan A, Darwiche H, Blanco J, Gillenwater A, Richards-Kortum R, Tkaczyk TS. Development of a multimodal foveated endomicroscope for the detection of oral cancer. Biomed Opt Express. 2017 Mar 01; 8(3):1525-1535.
PMID: 28663847; PMCID: PMC5480562.
-
Quinlan-Davidson SR, Morrison WH, Myers JN, Gunn GB, William WN, Beadle BM, Skinner HD, Gillenwater AM, Frank SJ, Phan J, Johnson FM, Fuller CD, Zafereo ME, Rosenthal DI, Garden AS. Recurrent oral cavity cancer: Patterns of failure after salvage multimodality therapy. Head Neck. 2017 04; 39(4):633-638.
PMID: 28006086.
Citations:
6 Fields:
Translation:
Humans
-
William WN, Papadimitrakopoulou V, Lee JJ, Mao L, Cohen EE, Lin HY, Gillenwater AM, Martin JW, Lingen MW, Boyle JO, Shin DM, Vigneswaran N, Shinn N, Heymach JV, Wistuba II, Tang X, Kim ES, Saintigny P, Blair EA, Meiller T, Gutkind JS, Myers J, El-Naggar A, Lippman SM. Erlotinib and the Risk of Oral Cancer: The Erlotinib Prevention of Oral Cancer (EPOC) Randomized Clinical Trial. JAMA Oncol. 2016 Feb; 2(2):209-16.
PMID: 26540028; PMCID: PMC4771491.
Citations:
51 Fields:
Translation:
Humans
-
Shinn EH, Valentine A, Jethanandani A, Basen-Engquist K, Fellman B, Urbauer D, Atkinson E, Yusuf SW, Lenihan D, Woods ML, Kies MS, Sood AK, Carmack C, Morrison WH, Gillenwater A, Sturgis EM, Garden AS. Depression and Oropharynx Cancer Outcome. Psychosom Med. 2016 Jan; 78(1):38-48.
PMID: 26632757; PMCID: PMC4696911.
Citations:
12 Fields:
Translation:
HumansCells
-
Bishop AJ, Garden AS, Gunn GB, Rosenthal DI, Beadle BM, Fuller CD, Levy LB, Gillenwater AM, Kies MS, Esmaeli B, Frank SJ, Phan J, Morrison WH. Merkel cell carcinoma of the head and neck: Favorable outcomes with radiotherapy. Head Neck. 2016 04; 38 Suppl 1:E452-8.
PMID: 25645649.
Citations:
6 Fields:
Translation:
Humans
-
Ishijima A, Schwarz RA, Shin D, Mondrik S, Vigneswaran N, Gillenwater AM, Anandasabapathy S, Richards-Kortum R. Automated frame selection process for high-resolution microendoscopy. J Biomed Opt. 2015 Apr; 20(4):46014.
PMID: 25919426; PMCID: PMC4412137.
Citations:
10 Fields:
Translation:
Humans
-
Gillenwater AM, Vigneswaran N, Fatani H, Saintigny P, El-Naggar AK. Proliferative verrucous leukoplakia: recognition and differentiation from conventional leukoplakia and mimics. Head Neck. 2014 Nov; 36(11):1662-8.
PMID: 24115154.
Citations:
8 Fields:
Translation:
Humans
-
Kawedia JD, Zhang YP, Myers AL, Richards-Kortum RR, Kramer MA, Gillenwater AM, Culotta KS. Physical and chemical stability of proflavine contrast agent solutions for early detection of oral cancer. J Oncol Pharm Pract. 2016 Feb; 22(1):21-5.
PMID: 25113309.
-
Hellebust A, Rosbach K, Wu JK, Nguyen J, Gillenwater A, Vigneswaran N, Richards-Kortum R. Vital-dye-enhanced multimodal imaging of neoplastic progression in a mouse model of oral carcinogenesis. J Biomed Opt. 2013 Dec; 18(12):126017.
PMID: 24362926; PMCID: PMC3869894.
Citations:
10 Fields:
Translation:
Animals
-
Vigneswaran N, Fatani H, Saintigny P, El-Naggar AK, Gillenwater AM. Proliferative verrucous leukoplakia (PVL): a review of an elusive pathologic entity! Adv Anat Pathol. 2013 Nov; 20(6):416-23.
PMID: 24113312.
Citations:
6 Fields:
Translation:
Humans
-
Bedard N, Schwarz RA, Hu A, Bhattar V, Howe J, Williams MD, Gillenwater AM, Richards-Kortum R, Tkaczyk TS. Multimodal snapshot spectral imaging for oral cancer diagnostics: a pilot study. Biomed Opt Express. 2013 Jun 01; 4(6):938-49.
PMID: 23760882; PMCID: PMC3675872.
-
Gillenwater AM, Frank SJ, Fatani H, El-Naggar AK. Primary intestinal-like adenocarcinoma of major salivary glands: 2 instances of previously undocumented phenotype. Head Neck. 2013 Aug; 35(8):E234-6.
PMID: 23108630.
Citations:
5 Fields:
Translation:
Humans
-
Rosbach KJ, Williams MD, Gillenwater AM, Richards-Kortum RR. Optical molecular imaging of multiple biomarkers of epithelial neoplasia: epidermal growth factor receptor expression and metabolic activity in oral mucosa. Transl Oncol. 2012 Jun; 5(3):160-71.
PMID: 22741035; PMCID: PMC3384270.
-
Pierce MC, Schwarz RA, Bhattar VS, Mondrik S, Williams MD, Lee JJ, Richards-Kortum R, Gillenwater AM. Accuracy of in vivo multimodal optical imaging for detection of oral neoplasia. Cancer Prev Res (Phila). 2012 Jun; 5(6):801-9.
PMID: 22551901; PMCID: PMC3560936.
Citations:
49 Fields:
Translation:
Humans
-
Vila PM, Park CW, Pierce MC, Goldstein GH, Levy L, Gurudutt VV, Polydorides AD, Godbold JH, Teng MS, Genden EM, Miles BA, Anandasabapathy S, Gillenwater AM, Richards-Kortum R, Sikora AG. Discrimination of benign and neoplastic mucosa with a high-resolution microendoscope (HRME) in head and neck cancer. Ann Surg Oncol. 2012 Oct; 19(11):3534-9.
PMID: 22492225; PMCID: PMC3421068.
Citations:
20 Fields:
Translation:
HumansCTClinical Trials
-
Levy LL, Vila PM, Park RW, Schwarz R, Polydorides AD, Teng MS, Gurudutt VV, Genden EM, Miles B, Anandasabapathy S, Gillenwater AM, Richards-Kortum R, Sikora AG. High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract: An Atlas for Image-Guided Surgery. ISRN Minim Invasive Surg. 2012; 2012.
PMID: 23641314; PMCID: PMC3639499.
-
Jerjes WK, Upile T, Wong BJ, Betz CS, Sterenborg HJ, Witjes MJ, Berg K, van Veen R, Biel MA, El-Naggar AK, Mosse CA, Olivo M, Richards-Kortum R, Robinson DJ, Rosen J, Yodh AG, Kendall C, Ilgner JF, Amelink A, Bagnato V, Barr H, Bolotine L, Bigio I, Chen Z, Choo-Smith LP, D'Cruz AK, Gillenwater A, Leunig A, MacRobert AJ, McKenzie G, Sandison A, Soo KC, Stepp H, Stone N, Svanberg K, Tan IB, Wilson BC, Wolfsen H, Hopper C. The future of medical diagnostics: review paper. Head Neck Oncol. 2011 Aug 23; 3:38.
PMID: 21861912; PMCID: PMC3180646.
Citations:
5 Fields:
Translation:
Humans
-
Muldoon TJ, Roblyer D, Williams MD, Stepanek VM, Richards-Kortum R, Gillenwater AM. Noninvasive imaging of oral neoplasia with a high-resolution fiber-optic microendoscope. Head Neck. 2012 Mar; 34(3):305-12.
PMID: 21413101; PMCID: PMC3078517.
Citations:
47 Fields:
Translation:
Humans
-
Upile T, Jerjes WK, Sterenborg HJ, Wong BJ, El-Naggar AK, Ilgner JF, Sandison A, Witjes MJ, Biel MA, van Veen R, Hamdoon Z, Gillenwater A, Mosse CA, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Barr H, Chen Z, Berg K, D'Cruz AK, Sudhoff H, Stone N, Kendall C, Fisher S, MacRobert AJ, Leunig A, Olivo M, Richards-Kortum R, Soo KC, Bagnato V, Choo-Smith LP, Svanberg K, Tan IB, Wilson BC, Wolfsen H, Bigio I, Yodh AG, Hopper C. At the frontiers of surgery: review. Head Neck Oncol. 2011 Feb 09; 3(1):7.
PMID: 21306627; PMCID: PMC3048561.
Citations:
3 Fields:
Translation:
Humans
-
Schwarz RA, Gao W, Stepanek VM, Le TT, Bhattar VS, Williams MD, Wu JK, Vigneswaran N, Adler-Storthz K, Gillenwater AM, Richards-Kortum R. Prospective evaluation of a portable depth-sensitive optical spectroscopy device to identify oral neoplasia. Biomed Opt Express. 2010 Dec 08; 2(1):89-99.
PMID: 21326639; PMCID: PMC3028502.
-
Roblyer D, Kurachi C, Stepanek V, Schwarz RA, Williams MD, El-Naggar AK, Lee JJ, Gillenwater AM, Richards-Kortum R. Comparison of multispectral wide-field optical imaging modalities to maximize image contrast for objective discrimination of oral neoplasia. J Biomed Opt. 2010 Nov-Dec; 15(6):066017.
PMID: 21198191; PMCID: PMC3013151.
Citations:
9 Fields:
Translation:
Humans
-
Vadhan-Raj S, Trent J, Patel S, Zhou X, Johnson MM, Araujo D, Ludwig JA, O'Roark S, Gillenwater AM, Bueso-Ramos C, El-Naggar AK, Benjamin RS. Single-dose palifermin prevents severe oral mucositis during multicycle chemotherapy in patients with cancer: a randomized trial. Ann Intern Med. 2010 Sep 21; 153(6):358-67.
PMID: 20855800.
Citations:
26 Fields:
Translation:
HumansCTClinical Trials
-
Shin D, Vigneswaran N, Gillenwater A, Richards-Kortum R. Advances in fluorescence imaging techniques to detect oral cancer and its precursors. Future Oncol. 2010 Jul; 6(7):1143-54.
PMID: 20624126; PMCID: PMC2929485.
Citations:
29 Fields:
Translation:
Humans
-
Shin D, Pierce MC, Gillenwater AM, Williams MD, Richards-Kortum RR. A fiber-optic fluorescence microscope using a consumer-grade digital camera for in vivo cellular imaging. PLoS One. 2010 Jun 23; 5(6):e11218.
PMID: 20585636; PMCID: PMC2890400.
Citations:
20 Fields:
Translation:
Humans
-
Rahman MS, Ingole N, Roblyer D, Stepanek V, Richards-Kortum R, Gillenwater A, Shastri S, Chaturvedi P. Evaluation of a low-cost, portable imaging system for early detection of oral cancer. Head Neck Oncol. 2010 Apr 22; 2:10.
PMID: 20409347; PMCID: PMC2867772.
Citations:
18 Fields:
Translation:
Humans
-
Bedard N, Pierce M, El-Nagger A, Anandasabapathy S, Gillenwater A, Richards-Kortum R. Emerging roles for multimodal optical imaging in early cancer detection: a global challenge. Technol Cancer Res Treat. 2010 Apr; 9(2):211-7.
PMID: 20218743; PMCID: PMC2906814.
Citations:
11 Fields:
Translation:
Humans
-
Fingeret MC, Vidrine DJ, Reece GP, Reece GP, Gillenwater AM, Gritz ER. Multidimensional analysis of body image concerns among newly diagnosed patients with oral cavity cancer. Head Neck. 2010 Mar; 32(3):301-9.
PMID: 19626634; PMCID: PMC2821979.
Citations:
34 Fields:
Translation:
Humans
-
Wang LE, Hu Z, Sturgis EM, Spitz MR, Strom SS, Amos CI, Guo Z, Qiao Y, Gillenwater AM, Myers JN, Clayman GL, Weber RS, El-Naggar AK, Mao L, Lippman SM, Hong WK, Wei Q. Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck cancer but not tumor characteristics. Clin Cancer Res. 2010 Jan 15; 16(2):764-74.
PMID: 20068090; PMCID: PMC2848391.
Citations:
26 Fields:
Translation:
HumansAnimalsCells
-
Ghosn B, van de Ven AL, Tam J, Gillenwater A, Sokolov KV, Richards-Kortum R, Roy K. Efficient mucosal delivery of optical contrast agents using imidazole-modified chitosan. J Biomed Opt. 2010 Jan-Feb; 15(1):015003.
PMID: 20210443; PMCID: PMC2839797.
Citations:
6 Fields:
Translation:
HumansAnimals
-
Levy L, Smith C, Gurudutt V, Teng M, Rivera M, Anadasabapathy S, Genden E, Gillenwater A, Richards-Kortum R, Sikora A. Ex vivo high resolution imaging with a miniaturized microendoscope to discriminate between benign and malignant mucosa in the upper aerodigestive tract. Laryngoscope. 2010; 120 Suppl 4:S162.
PMID: 21225760.
Citations: Fields:
Translation:
Humans
-
Tsao AS, Liu D, Martin J, Tang XM, Lee JJ, El-Naggar AK, Wistuba I, Culotta KS, Mao L, Gillenwater A, Sagesaka YM, Hong WK, Papadimitrakopoulou V. Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions. Cancer Prev Res (Phila). 2009 Nov; 2(11):931-41.
PMID: 19892663; PMCID: PMC4243312.
Citations:
82 Fields:
Translation:
HumansCTClinical Trials
-
Vigneswaran N, Koh S, Gillenwater A. Incidental detection of an occult oral malignancy with autofluorescence imaging: a case report. Head Neck Oncol. 2009 Oct 28; 1:37.
PMID: 19863814; PMCID: PMC2778639.
Citations:
6 Fields:
Translation:
Humans
-
Funk E, Ivan D, Gillenwater AM. Ecthyma gangrenosum: an unusual cutaneous manifestation of the head and neck. Arch Otolaryngol Head Neck Surg. 2009 Aug; 135(8):818-20.
PMID: 19687405.
Citations:
6 Fields:
Translation:
HumansCells
-
Upile T, Jerjes W, Sterenborg HJ, El-Naggar AK, Sandison A, Witjes MJ, Biel MA, Bigio I, Wong BJ, Gillenwater A, MacRobert AJ, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Mosse CA, Barr H, Chen Z, Berg K, D'Cruz AK, Stone N, Kendall C, Fisher S, Leunig A, Olivo M, Richards-Kortum R, Soo KC, Bagnato V, Choo-Smith LP, Svanberg K, Tan IB, Wilson BC, Wolfsen H, Yodh AG, Hopper C. Head & neck optical diagnostics: vision of the future of surgery. Head Neck Oncol. 2009 Jul 13; 1:25.
PMID: 19594907; PMCID: PMC2720388.
Citations:
16 Fields:
Translation:
Humans
-
Nitin N, Carlson AL, Muldoon T, El-Naggar AK, Gillenwater A, Richards-Kortum R. Molecular imaging of glucose uptake in oral neoplasia following topical application of fluorescently labeled deoxy-glucose. Int J Cancer. 2009 Jun 01; 124(11):2634-42.
PMID: 19173294; PMCID: PMC2700039.
Citations:
37 Fields:
Translation:
HumansCells
-
Nitin N, Rosbach KJ, El-Naggar A, Williams M, Gillenwater A, Richards-Kortum RR. Optical molecular imaging of epidermal growth factor receptor expression to improve detection of oral neoplasia. Neoplasia. 2009 Jun; 11(6):542-51.
PMID: 19484143; PMCID: PMC2685443.
Citations:
18 Fields:
Translation:
HumansAnimalsCells
-
Roblyer D, Kurachi C, Stepanek V, Williams MD, El-Naggar AK, Lee JJ, Gillenwater AM, Richards-Kortum R. Objective detection and delineation of oral neoplasia using autofluorescence imaging. Cancer Prev Res (Phila). 2009 May; 2(5):423-31.
PMID: 19401530; PMCID: PMC2719708.
Citations:
59 Fields:
Translation:
HumansPHPublic Health
-
Schwarz RA, Gao W, Redden Weber C, Kurachi C, Lee JJ, El-Naggar AK, Richards-Kortum R, Gillenwater AM. Noninvasive evaluation of oral lesions using depth-sensitive optical spectroscopy. Cancer. 2009 Apr 15; 115(8):1669-79.
PMID: 19170229; PMCID: PMC2728679.
Citations:
43 Fields:
Translation:
Humans
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Holsinger FC, Kies MS, Diaz EM, Gillenwater AM, Lewin JS, Ginsberg LE, Glisson BS, Garden AS, Ark N, Lin HY, Lee JJ, El-Naggar AK, Ki Hong W, Shin DM, Khuri FR. Durable long-term remission with chemotherapy alone for stage II to IV laryngeal cancer. J Clin Oncol. 2009 Apr 20; 27(12):1976-82.
PMID: 19289628; PMCID: PMC2738635.
Citations:
13 Fields:
Translation:
Humans
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Pavlova I, Weber CR, Schwarz RA, Williams MD, Gillenwater AM, Richards-Kortum R. Fluorescence spectroscopy of oral tissue: Monte Carlo modeling with site-specific tissue properties. J Biomed Opt. 2009 Jan-Feb; 14(1):014009.
PMID: 19256697; PMCID: PMC2722954.
Citations:
17 Fields:
Translation:
Humans
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Papadimitrakopoulou V, Izzo JG, Liu DD, Myers J, Ceron TL, Lewin J, William WN, Atwell A, Lee JJ, Gillenwater A, El-Naggar A, Wu X, Lippman SM, Hittelman WN, Hong WK. Cyclin D1 and cancer development in laryngeal premalignancy patients. Cancer Prev Res (Phila). 2009 Jan; 2(1):14-21.
PMID: 19139013; PMCID: PMC4243520.
Citations:
12 Fields:
Translation:
Humans
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Pavlova I, Weber CR, Schwarz RA, Williams M, El-Naggar A, Gillenwater A, Richards-Kortum R. Monte Carlo model to describe depth selective fluorescence spectra of epithelial tissue: applications for diagnosis of oral precancer. J Biomed Opt. 2008 Nov-Dec; 13(6):064012.
PMID: 19123659; PMCID: PMC2615394.
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Rahman M, Chaturvedi P, Gillenwater AM, Richards-Kortum R. Low-cost, multimodal, portable screening system for early detection of oral cancer. J Biomed Opt. 2008 May-Jun; 13(3):030502.
PMID: 18601519.
Citations:
18 Fields:
Translation:
HumansPHPublic Health
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Yildirim G, Gillenwater AM, Ordonez NG, Garden AS, El-Naggar AK. Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. Head Neck. 2008 May; 30(5):675-9.
PMID: 17972308.
Citations:
1 Fields:
Translation:
HumansCells
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Pavlova I, Williams M, El-Naggar A, Richards-Kortum R, Gillenwater A. Understanding the biological basis of autofluorescence imaging for oral cancer detection: high-resolution fluorescence microscopy in viable tissue. Clin Cancer Res. 2008 Apr 15; 14(8):2396-404.
PMID: 18413830; PMCID: PMC2773159.
Citations:
82 Fields:
Translation:
Humans
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Maitland KC, Gillenwater AM, Williams MD, El-Naggar AK, Descour MR, Richards-Kortum RR. In vivo imaging of oral neoplasia using a miniaturized fiber optic confocal reflectance microscope. Oral Oncol. 2008 Nov; 44(11):1059-66.
PMID: 18396445; PMCID: PMC2673342.
Citations:
40 Fields:
Translation:
Humans
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Nieman LT, Kan CW, Gillenwater A, Markey MK, Sokolov K. Probing local tissue changes in the oral cavity for early detection of cancer using oblique polarized reflectance spectroscopy: a pilot clinical trial. J Biomed Opt. 2008 Mar-Apr; 13(2):024011.
PMID: 18465974.
Citations:
15 Fields:
Translation:
HumansCTClinical Trials
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Citations:
70 Fields:
Translation:
Humans
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Schwarz RA, Gao W, Daye D, Williams MD, Richards-Kortum R, Gillenwater AM. Autofluorescence and diffuse reflectance spectroscopy of oral epithelial tissue using a depth-sensitive fiber-optic probe. Appl Opt. 2008 Feb 20; 47(6):825-34.
PMID: 18288232; PMCID: PMC2773166.
Citations:
39 Fields:
Translation:
Humans
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Muldoon TJ, Pierce MC, Nida DL, Williams MD, Gillenwater A, Richards-Kortum R. Subcellular-resolution molecular imaging within living tissue by fiber microendoscopy. Opt Express. 2007 Dec 10; 15(25):16413-23.
PMID: 19550931; PMCID: PMC3065245.
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Gillenwater AM, Zhong M, Lotan R. Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells. Mol Cancer Ther. 2007 Nov; 6(11):2967-75.
PMID: 18025281.
Citations:
35 Fields:
Translation:
HumansCells
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Carlson AL, Gillenwater AM, Williams MD, El-Naggar AK, Richards-Kortum RR. Confocal microscopy and molecular-specific optical contrast agents for the detection of oral neoplasia. Technol Cancer Res Treat. 2007 Oct; 6(5):361-74.
PMID: 17877424; PMCID: PMC2772068.
Citations:
3 Fields:
Translation:
HumansCells
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Carlson AL, Coghlan LG, Gillenwater AM, Richards-Kortum RR. Dual-mode reflectance and fluorescence near-video-rate confocal microscope for architectural, morphological and molecular imaging of tissue. J Microsc. 2007 Oct; 228(Pt 1):11-24.
PMID: 17910693.
Citations:
12 Fields:
Translation:
HumansAnimals
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Arifler D, Pavlova I, Gillenwater A, Richards-Kortum R. Light scattering from collagen fiber networks: micro-optical properties of normal and neoplastic stroma. Biophys J. 2007 May 01; 92(9):3260-74.
PMID: 17307834; PMCID: PMC1852360.
Citations:
37 Fields:
Translation:
HumansCells
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Truong AT, Truong DT, Gillenwater AM, Rozner MA. Gastric aspiration in patients with a laryngectomy stoma: is it possible? J Clin Anesth. 2006 Nov; 18(7):557-8.
PMID: 17126793.
Citations: Fields:
Translation:
Humans
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Safdar A, Gillenwater AM, Jones DM, Jorgensen JL, Romaguera JE. Rosai-Dorfman disease misdiagnosed as active tuberculosis. Leuk Lymphoma. 2006 Jul; 47(7):1441-2.
PMID: 16923590.
Citations:
1 Fields:
Translation:
Humans
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Hsu ER, Gillenwater AM, Hasan MQ, Williams MD, El-Naggar AK, Richards-Kortum RR. Real-time detection of epidermal growth factor receptor expression in fresh oral cavity biopsies using a molecular-specific contrast agent. Int J Cancer. 2006 Jun 15; 118(12):3062-71.
PMID: 16395711.
Citations:
4 Fields:
Translation:
Humans
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Gillenwater AM, Chambers MS. Diagnosis of premalignant lesions and early cancers of the oral cavity. Tex Dent J. 2006 Jun; 123(6):512-20.
PMID: 16875018.
Citations: Fields:
Translation:
Humans
-
Citations:
22 Fields:
Translation:
HumansPHPublic Health
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Lewin JS, Barringer DA, May AH, Gillenwater AM, Arnold KA, Roberts DB, Yu P. Functional outcomes after laryngopharyngectomy with anterolateral thigh flap reconstruction. Head Neck. 2006 Feb; 28(2):142-9.
PMID: 16302192.
Citations:
9 Fields:
Translation:
Humans
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Takada Y, Gillenwater A, Ichikawa H, Aggarwal BB. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation. J Biol Chem. 2006 Mar 03; 281(9):5612-22.
PMID: 16377638.
Citations:
34 Fields:
Translation:
HumansAnimalsCells
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Hsu ER, Gillenwater AM, Richards-Kortum RR. Detection of the molecular changes associated with oral cancer using a molecular-specific fluorescent contrast agent and single-wavelength spectroscopy. Appl Spectrosc. 2005 Sep; 59(9):1166-73.
PMID: 16197641.
Citations:
2 Fields:
Translation:
HumansCells
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Lewin JS, Barringer DA, May AH, Gillenwater AM, Arnold KA, Roberts DB, Yu P. Functional outcomes after circumferential pharyngoesophageal reconstruction. Laryngoscope. 2005 Jul; 115(7):1266-71.
PMID: 15995519.
Citations:
17 Fields:
Translation:
Humans
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Gillenwater A, Lewin J, Roberts D, El-Naggar A. Moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the larynx: a clinically aggressive tumor. Laryngoscope. 2005 Jul; 115(7):1191-5.
PMID: 15995505.
Citations:
9 Fields:
Translation:
Humans
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Schwarz RA, Arifler D, Chang SK, Pavlova I, Hussain IA, Mack V, Knight B, Richards-Kortum R, Gillenwater AM. Ball lens coupled fiber-optic probe for depth-resolved spectroscopy of epithelial tissue. Opt Lett. 2005 May 15; 30(10):1159-61.
PMID: 15945140; PMCID: PMC2773162.
Citations:
18 Fields:
Translation:
HumansAnimals
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Tomsett KL, Chambers MS, Martin JW, Gillenwater AM, Lemon JC. A technique for the fabrication of an immediate mandibular surgical stent securing a skin graft. J Prosthet Dent. 2005 Apr; 93(4):395-7.
PMID: 15798691.
Citations:
1 Fields:
Translation:
Humans
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Carlson K, Chidley M, Sung KB, Descour M, Gillenwater A, Follen M, Richards-Kortum R. In vivo fiber-optic confocal reflectance microscope with an injection-molded plastic miniature objective lens. Appl Opt. 2005 Apr 01; 44(10):1792-7.
PMID: 15813514.
Citations:
35 Fields:
Translation:
Humans
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Svistun E, Alizadeh-Naderi R, El-Naggar A, Jacob R, Gillenwater A, Richards-Kortum R. Vision enhancement system for detection of oral cavity neoplasia based on autofluorescence. Head Neck. 2004 Mar; 26(3):205-15.
PMID: 14999795.
Citations:
28 Fields:
Translation:
Humans
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Hsu ER, Anslyn EV, Dharmawardhane S, Alizadeh-Naderi R, Aaron JS, Sokolov KV, El-Naggar AK, Gillenwater AM, Richards-Kortum RR. A far-red fluorescent contrast agent to image epidermal growth factor receptor expression. Photochem Photobiol. 2004 Mar; 79(3):272-9.
PMID: 15115300.
Citations:
11 Fields:
Translation:
HumansCells
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Sokolov K, Nieman LT, Myakov A, Gillenwater A. Polarized reflectance spectroscopy for pre-cancer detection. Technol Cancer Res Treat. 2004 Feb; 3(1):1-14.
PMID: 14750888.
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Papadimitrakopoulou VA, Ginsberg LE, Garden AS, Kies MS, Glisson BS, Diaz EM, Clayman G, Morrison WH, Liu DD, Blumenschein G, Lippman SM, Schommer D, Gillenwater A, Goepfert H, Hong WK. Intraarterial cisplatin with intravenous paclitaxel and ifosfamide as an organ-preservation approach in patients with paranasal sinus carcinoma. Cancer. 2003 Nov 15; 98(10):2214-23.
PMID: 14601092.
Citations:
9 Fields:
Translation:
HumansCTClinical Trials
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Clark AL, Gillenwater AM, Collier TG, Alizadeh-Naderi R, El-Naggar AK, Richards-Kortum RR. Confocal microscopy for real-time detection of oral cavity neoplasia. Clin Cancer Res. 2003 Oct 15; 9(13):4714-21.
PMID: 14581341.
Citations:
30 Fields:
Translation:
HumansCells
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Esmaeli B, Ahmadi MA, Gillenwater AM, Faustina MM, Amato M. The role of supraorbital nerve biopsy in cutaneous malignancies of the periocular region. Ophthalmic Plast Reconstr Surg. 2003 Jul; 19(4):282-6.
PMID: 12878876.
Citations:
6 Fields:
Translation:
Humans
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Utzinger U, Bueeler M, Oh S, Heintzelman DL, Svistun ES, Abd-El-Barr M, Gillenwater A, Richards-Kortum R. Optimal visual perception and detection of oral cavity neoplasia. IEEE Trans Biomed Eng. 2003 Mar; 50(3):396-9.
PMID: 12669997.
Citations:
4 Fields:
Translation:
Humans
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Lewin JS, Gillenwater AM, Garrett JD, Bishop-Leone JK, Nguyen DD, Callender DL, Ayers GD, Myers JN. Characterization of laryngopharyngeal reflux in patients with premalignant or early carcinomas of the larynx. Cancer. 2003 Feb 15; 97(4):1010-4.
PMID: 12569600.
Citations:
17 Fields:
Translation:
Humans
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Choi HR, Tucker SA, Huang Z, Gillenwater AM, Luna MA, Batsakis JG, El-Naggar AK. Differential expressions of cyclin-dependent kinase inhibitors (p27 and p21) and their relation to p53 and Ki-67 in oral squamous tumorigenesis. Int J Oncol. 2003 Feb; 22(2):409-14.
PMID: 12527941.
Citations:
10 Fields:
Translation:
HumansCells
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Eicher SA, Clayman GL, Myers JN, Gillenwater AM. A prospective study of intraoperative lymphatic mapping for head and neck cutaneous melanoma. Arch Otolaryngol Head Neck Surg. 2002 Mar; 128(3):241-6.
PMID: 11886337.
Citations:
11 Fields:
Translation:
Humans
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Clark A, Collier T, Lacy A, Follen M, Malpica A, Gillenwater A, Richards-Kortum R. Detection of dysplasia with near real time confocal microscopy. Biomed Sci Instrum. 2002; 38:393-8.
PMID: 12085638.
Citations:
2 Fields:
Translation:
Humans
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Gillenwater AM, Goepfert H. Surgical management of laryngotracheal and esophageal involvement by locally advanced thyroid cancer. Semin Surg Oncol. 1999 Jan-Feb; 16(1):19-29.
PMID: 9890736.
Citations:
7 Fields:
Translation:
Humans
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Ginsberg LE, De Monte F, Gillenwater AM. Greater superficial petrosal nerve: anatomy and MR findings in perineural tumor spread. AJNR Am J Neuroradiol. 1996 Feb; 17(2):389-93.
PMID: 8938317; PMCID: PMC8338384.
Citations:
22 Fields:
Translation:
Humans
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In Vivo fiber confocal microscopy for detection of oral cavity neoplasia.
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Cancer screening through the use of enhanced visual systems. 22-23.
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High-resolution imaging within tissue by fiber microendoscopy.
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Near real time confocal imaging of dysplasia in the oral cavity. 982-983.
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Merkel cell carcinoma of the head and neck. Head and Neck. 38:E452-E458.
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Intraoperative diagnostics and elimination of residual microtumours with plasmonic nanobubbles. Nature Nanotechnology.
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Real-time spectroscopic evaluation of oral lesions and comparisons with histopathology.
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Fluorescence and reflectance spectroscopy for detection of oral dysplasia and cancer. 431-449.
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Plasmonic nanobubble theranostics for intra-operative and preventive treatment of head and neck squamous cell carcinoma.
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Confocal microscopy and optical contrast agents for in vivo detection of cancer. Microscopy and Microanalysis. 14:728-729.
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Oral cancer screening approach based on labeling exfoliated oral cells with molecularly-targeted optical contrast agents.
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Longitudinal evaluation of patients with oral potentially malignant disorders using optical imaging and spectroscopy.
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Automated frame selection process for analyzing high resolution microendoscope images.
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Automated frame selection process for high-resolution microendoscopy. Journal of Biomedical Optics. 20.
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Low-cost, portable imaging systems for cancer detection.
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Noninvasive optical imaging and spectroscopy for quantitative monitoring of the progression of oral premalignant lesions.
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Computational analysis of light scattering from collagen fiber networks.
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Recurrent oral cavity cancer. Head and Neck.
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Programmable bio-nanochip-based cytologic testing of oral potentially malignant disorders in Fanconi anemia. Oral Diseases. 21:593-601.
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Optical sectioning wide-field microscopy for imaging oral cancer. 2306-2307.
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Depth sensitive optical spectroscopy for noninvasive detection of oral cavity neoplasia.
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Wide-field and high-resolution optical imaging for early detection of oral neoplasia.
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Depth-sensitive spectroscopic measurements of patients with oral mucosal lesions.
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Miniature injection-molded optics for fiber-optic, in vivo confocal microscopy. 126-136.
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Combined fluorescence and reflectance spectroscopy. 306-307.
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Molecular imaging of carcinogenesis with immuno-targeted nanoparticles. 5292-5295.
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Fluorescence excitation emission matrices of human tissue. Applied Spectroscopy. 53:302-311.
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Depression and oropharynx cancer outcome. Psychosomatic Medicine. 78:38-48.
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Computational analysis of light scattering from collagen fiber networks.
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In vivo fluorescence hyperspectral imaging of oral neoplasia.
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Multispectral and hyperspectral in vivo imaging of the oral cavity for neoplastic tissue detection.
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Optical molecular imaging of multiple Biomarkers of epithelial neoplasia. Translational Oncology. 5:160-171.
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Erlotinib and the risk of oral cancer the erlotinib Prevention of Oral Cancer (EPOC) randomized clinical trial. JAMA oncology. 2:209-216.