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ANIRBAN MAITRA
Title
Professor
Institution
MD Anderson
Department
Pathology
Address
6565 MD Anderson Blvd
Houston TX 77030
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Ying H
, Kimmelman AC, Bardeesy N,
Kalluri R
,
Maitra A
,
DePinho RA
, Ying H. Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev. 2025 Jan 07; 39(1-2):36-63.
PMID:
39510840
.
Citations:
Fields:
Mol
Molecular Biology
Nishiwaki N, Sugiura K, Suzuki K, Li AL, Contreras CT, Efe G, Shin AE, Sadeghian D, Zhao J, Maitra A, Pitarresi JR, Sims PA, Chandwani R, Rustgi AK, Nishiwaki N, Sugiura K, Suzuki K, Li AL, Tapia Contreras C, Efe G, Shin AE, Sadeghian D, Zhao J,
Maitra A
, Pitarresi JR, Sims PA, Chandwani R, Rustgi AK. PRRX1 Has Functional Roles in Pancreatic Acinar to Ductal Metaplasia and Carcinogenesis. Cell Mol Gastroenterol Hepatol. 2024 Dec 16; 101442.
PMID:
39694413
.
Citations:
Fields:
Gas
Gastroenterology
Makino Y, Rajapakshe KI, Chellakkan Selvanesan B, Okumura T, Date K, Dutta P, Abou-Elkacem L, Sagara A, Min J, Sans M, Yee N, Siemann MJ, Enriquez J, Smith P,
Bhattacharya P
, Kim M, Dede M, Hart T,
Maitra A
, Thege FI. Metabolic reprogramming by mutant GNAS creates an actionable dependency in intraductal papillary mucinous neoplasms of the pancreas. Gut. 2024 Dec 10; 74(1):75-88.
PMID:
39277181
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Cloyd JM, Sarna A, Arango MJ, Bates SE,
Bhutani MS
, Bloomston M, Chung V, Dotan E, Ferrone CR, Gambino PF, Goenka AH, Goodman KA, Hall WA, He J, Hogg ME, Jayaraman S, Kambadakone A,
Katz MHG
, Khorana AA, Ko AH,
Koay EJ
, Kooby DA, Krishna SG, Larsson LK, Lee RT,
Maitra A
, Massarweh NN, Mikhail S, Muzaffar M, O'Reilly EM, Palta M, Petzel MQB, Philip PA, Reyngold M, Santa Mina D, Sohal DPS, Sundaresan TK, Tsai S, Turner KL, Vreeland TJ, Walston S, Washington MK, Williams TM, Wo JY, Snyder RA. Best Practices for Delivering Neoadjuvant Therapy in Pancreatic Ductal Adenocarcinoma. JAMA Surg. 2024 Dec 04.
PMID:
39630427
; PMCID:
PMC11618571
.
Citations:
Fields:
Gen
General Surgery
Alewine C, Harris CC,
Maitra A
, Pine SR, Tuveson D. Editorial: special issue on the latest advances and challenges in pancreas cancer research in memory of S. Perwez Hussain. Carcinogenesis. 2024 Nov 22; 45(11):799-800.
PMID:
39578244
.
Citations:
Fields:
Neo
Neoplasms
Carpenter ES, Vendramini-Costa DB, Hasselluhn MC, Maitra A, Olive KP, Cukierman E, Pasca di Magliano M, Sherman MH, Carpenter ES, Vendramini-Costa DB, Hasselluhn MC,
Maitra A
, Olive KP, Cukierman E, Pasca di Magliano M, Sherman MH. Pancreatic Cancer-Associated Fibroblasts: Where Do We Go from Here? Cancer Res. 2024 Nov 04; 84(21):3505-3508.
PMID:
39283867
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Dilly J, Hoffman MT, Abbassi L, Li Z, Paradiso F, Parent BD, Hennessey CJ, Jordan AC, Morgado M, Dasgupta S, Uribe GA, Yang A, Kapner KS, Hambitzer FP, Qiang L, Feng H, Geisberg J, Wang J, Evans KE, Lyu H, Schalck A, Feng N, Lopez AM, Bristow CA, Kim MP, Rajapakshe KI, Bahrambeigi V, Roth JA, Garg K, Guerrero PA, Stanger BZ, Cristea S, Lowe SW, Baslan T, Van Allen EM, Mancias JD, Chan E, Anderson A, Katlinskaya YV, Shalek AK, Hong DS,
Pant S
, Hallin J, Anderes K, Olson P, Heffernan TP, Chugh S, Christensen JG, Maitra A, Wolpin BM, Raghavan S, Nowak JA, Winter PS, Dougan SK, Aguirre AJ, Dilly J, Hoffman MT, Abbassi L, Li Z, Paradiso F, Parent BD, Hennessey CJ, Jordan AC, Morgado M, Dasgupta S, Uribe GA, Yang A, Kapner KS, Hambitzer FP, Qiang L, Feng H, Geisberg J, Wang J, Evans KE, Lyu H, Schalck A, Feng N, Lopez AM, Bristow CA, Kim MP, Rajapakshe KI, Bahrambeigi V, Roth JA, Garg K, Guerrero PA, Stanger BZ, Cristea S, Lowe SW, Baslan T, Van Allen EM, Mancias JD, Chan E, Anderson A, Katlinskaya YV, Shalek AK,
Hong DS
, Pant S, Hallin J, Anderes K, Olson P, Heffernan TP, Chugh S, Christensen JG,
Maitra A
, Wolpin BM, Raghavan S, Nowak JA, Winter PS, Dougan SK, Aguirre AJ. Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer. Cancer Discov. 2024 Nov 01; 14(11):2135-2161.
PMID:
38975874
; PMCID:
PMC11528210
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Saito Y, Xiao Y,
Yao J
, Li Y, Liu W, Yuzhalin AE, Shyu YM, Li H, Yuan X, Li P, Zhang Q, Li Z, Wei Y, Yin X, Zhao J, Kariminia SM, Wu YC, Wang J, Yang J,
Xia W
, Sun Y, Jho EH,
Chiao PJ
,
Hwang RF
,
Ying H
, Wang H, Zhao Z,
Maitra A
,
Hung MC
,
DePinho RA
,
Yu D
. Targeting a chemo-induced adaptive signaling circuit confers therapeutic vulnerabilities in pancreatic cancer. Cell Discov. 2024 Oct 29; 10(1):109.
PMID:
39468013
; PMCID:
PMC11519973
.
Citations:
Li CF, Bai LY, Wei Y, Lee HH, Yang R, Yao J, Wang H, Wang YN, Chang WC, Shen YC, Wang SC, Chou CW, Fu J, Ling J, Chu YY, Chiu CF, Wang M, Yu D,
Chiao PJ
, Liang H,
Maitra A
, Ying H,
Hung MC
. All-trans retinoic acid-mediated ADAR1 degradation synergizes with PD-1 blockade to suppress pancreatic cancer. bioRxiv. 2024 Oct 23.
PMID:
39484589
; PMCID:
PMC11527022
.
Citations:
Balachandran Pillai A, Yousef M, Yousef A, Alfaro-Munoz KD, Smaglo BG, Willis J,
Wolff RA
,
Pant S
, Hurd MW,
Maitra A
, Wang H,
Katz MHG
, Prakash LR,
Tzeng CD
, Snyder R, Castelnovo LF, Chen A, Kravets A, Kudriavtseva K, Tarasov A, Kryukov K,
Ying H
, Shen JP,
Zhao D
. Molecular and Clinical Features of Pancreatic Acinar Cell Carcinoma: A Single-Institution Case Series. Cancers (Basel). 2024 Oct 09; 16(19).
PMID:
39410042
; PMCID:
PMC11475689
.
Citations:
Zhao M,
Maitra A
, Nowak JA. Big insights from small samples: uncovering the potential of EUS-guided FNAs in pancreatic cancer through predictive genomics and transcriptomics. EBioMedicine. 2024 Nov; 109:105380.
PMID:
39369615
; PMCID:
PMC11490758
.
Citations:
Fields:
Gen
Genetics
Med
Medicine (General)
Faupel-Badger J, Kohaar I, Bahl M, Chan AT, Campbell JD, Ding L, De Marzo AM,
Maitra A
, Merrick DT,
Hawk ET
,
Wistuba II
, Ghobrial IM, Lippman SM,
Lu KH
, Lawler M, Kay NE, Tlsty TD, Rebbeck TR, Srivastava S, Precancer Think Tank Team. Defining precancer: a grand challenge for the cancer community. Nat Rev Cancer. 2024 Nov; 24(11):792-809.
PMID:
39354069
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Taherian M,
Katz MHG
, Prakash LR, Wei D, Tong YT, Lai Z, Chatterjee D, Wang H, Kim M,
Tzeng CD
, Ikoma N,
Wolff RA
,
Zhao D
,
Koay EJ
,
Maitra A
, Wang H. The Association between Sampling and Survival in Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreaticoduodenectomy. Cancers (Basel). 2024 Sep 27; 16(19).
PMID:
39409932
; PMCID:
PMC11476037
.
Citations:
Aguirre AJ, Stanger BZ,
Maitra A
. Hope on the Horizon: A Revolution in KRAS Inhibition Is Creating a New Treatment Paradigm for Patients with Pancreatic Cancer. Cancer Res. 2024 Sep 16; 84(18):2950-2953.
PMID:
39279379
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Haab B, Qian L, Staal B, Jain M, Fahrmann J, Worthington C, Prosser D, Velokokhatnaya L, Lopez C, Tang R, Hurd MW, Natarajan G, Kumar S, Smith L,
Hanash S
, Batra SK,
Maitra A
, Lokshin A, Huang Y, Brand RE. A rigorous multi-laboratory study of known PDAC biomarkers identifies increased sensitivity and specificity over CA19-9 alone. Cancer Lett. 2024 Nov 01; 604:217245.
PMID:
39276915
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Yang D, Sun X, Moniruzzaman R, Wang H, Citu C, Zhao Z,
Wistuba II
, Wang H,
Maitra A
, Chen Y. Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation. Cell Rep Med. 2024 Sep 17; 5(9):101711.
PMID:
39232498
; PMCID:
PMC11525027
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Shui L,
Maitra A
,
Yuan Y
, Lau K, Kaur H, Li L, Li Z, Translational and Basic Science Research in Early Lesions (TBEL) Program. PoweREST: Statistical Power Estimation for Spatial Transcriptomics Experiments to Detect Differentially Expressed Genes Between Two Conditions. bioRxiv. 2024 Sep 01.
PMID:
39257799
; PMCID:
PMC11384012
.
Citations:
Patterson L, Toledo FG,
Maitra A
, Chari ST, Patterson L, Toledo FGS, Chari ST, Chari ST. Pancreatic Cancer-Induced Metabolic Dysregulation Syndrome: Clinical Profile, Proposed Mechanisms, and Unanswered Questions. Gastroenterology. 2024 Dec; 167(7):1251-1255.
PMID:
39222716
.
Citations:
Fields:
Gas
Gastroenterology
Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi MP, Lazcano R, Yamashita K, Xu Z, Pei G, Cho KS, Chu Y, Sinjab A, Peng F, Yan X, Han G, Wang R, Dai E, Dai Y,
Czerniak BA
,
Futreal A
,
Maitra A
,
Lazar A
, Kadara H,
Jazaeri AA
, Cheng X,
Ajani J
,
Gao J
, Hu J, Wang L. METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics. Nat Commun. 2024 Aug 25; 15(1):7312.
PMID:
39181865
; PMCID:
PMC11344794
.
Citations:
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Li AL, Sugiura K, Nishiwaki N, Suzuki K, Sadeghian D, Zhao J,
Maitra A
, Falvo D, Chandwani R, Pitarresi JR, Sims PA, Rustgi AK. FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia. Dev Cell. 2024 Nov 18; 59(22):3025-3042.e7.
PMID:
39178842
; PMCID:
PMC11576252
.
Citations:
Fields:
Cel
Cell Biology
Emb
Embryology
Translation:
Animals
Cells
Takeda M, Theardy MS, Sorokin A, Coker O, Kanikarla P, Chen S, Yang Z, Nguyen P, Wei Y, Yao J, Wang X, Yan L, Jin Y, Cai Y, Paku M, Chen Z, Li KZ, Citron F, Tomihara H, Gao S, Deem AK, Zhao J, Wang H,
Hanash S
,
DePinho RA
,
Maitra A
,
Draetta GF
, Ying H, Kopetz S, Yao W. Therapeutic targeting of Syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers. bioRxiv. 2024 Aug 08.
PMID:
39211217
; PMCID:
PMC11361106
.
Citations:
Treekitkarnmongkol W, Dai J, Liu S, Sankaran D, Nguyen T,
Balasenthil S
, Hurd MW, Chen M, Katayama H, Roy-Chowdhuri S,
Calin GA
, Brand RE, Lampe PD, Hu TY,
Maitra A
,
Koay EJ
,
Killary AM
,
Sen S
. Blood-Based microRNA Biomarker Signature of Early-Stage Pancreatic Ductal Adenocarcinoma With Lead-Time Trajectory in Prediagnostic Samples. Gastro Hep Adv. 2024; 3(8):1098-1115.
PMID:
39529638
; PMCID:
PMC11550741
.
Citations:
Li L,
McAllister F
,
Maitra A
. The liver casts a wide NET for metastatic pancreatic cancer. Nat Med. 2024 Aug; 30(8):2125-2126.
PMID:
38992125
.
Citations:
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Yousef M, Hurd MW, Yousef A, Ludmir EB, Pillai AB, Peterson J,
Koay EJ
, Albarouki S,
Tzeng CW
, Snyder R,
Katz MHG
, Wang H,
Overman MJ
,
Maitra A
,
Pant S
, Smaglo BG,
Wolff RA
,
Yao J
, Shen JP,
Zhao D
. Clinical and molecular characteristics of patients with brain metastasis secondary to pancreatic ductal adenocarcinoma. Oncologist. 2024 Jul 16.
PMID:
39014543
.
Citations:
Fields:
Neo
Neoplasms
Anandhan S, Herbrich S,
Goswami S
, Guan B, Chen Y, Macaluso MD, Jindal S, Natarajan SM, Andrewes SW, Xiong L, Nagarajan A, Basu S, Tang DN, Liu J, Min J,
Maitra A
,
Sharma P
. TSG-6+ cancer-associated fibroblasts modulate myeloid cell responses and impair anti-tumor response to immune checkpoint therapy in pancreatic cancer. Nat Commun. 2024 Jul 10; 15(1):5291.
PMID:
38987547
; PMCID:
PMC11237123
.
Citations:
1
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Li C, Hong W, Reuben A, Wang L, Maitra A, Zhang J, Cheng C, Li C, Hong W, Reuben A, Wang L,
Maitra A
, Zhang J, Cheng C. TimiGP-Response: the pan-cancer immune landscape associated with response to immunotherapy. bioRxiv. 2024 Jun 27.
PMID:
38979334
; PMCID:
PMC11230183
.
Citations:
Haab B, Qian L, Staal B, Jain M, Fahrmann J, Worthington C, Prosser D, Velokokhatnaya L, Lopez C, Tang R, Hurd MW, Natarajan G, Kumar S, Smith L,
Hanash S
, Batra SK,
Maitra A
, Lokshin A, Huang Y, Brand RE. A Rigorous Multi-Laboratory Study of Known PDAC Biomarkers Identifies Increased Sensitivity and Specificity Over CA19-9 Alone. bioRxiv. 2024 May 26.
PMID:
38826212
; PMCID:
PMC11142185
.
Citations:
Bahrambeigi V, Lee JJ, Branchi V, Rajapakshe KI, Xu Z, Kui N, Henry JT, Wang K, Stephens BM, Dhebat S, Hurd MW, Sun R, Yang P, Ruppin E, Wang W, Kopetz S, Maitra A, Guerrero PA, Bahrambeigi V, Lee JJ, Branchi V, Rajapakshe KI, Xu Z, Kui N, Henry JT, Kun W, Stephens BM, Dhebat S, Hurd MW, Sun R, Yang P, Ruppin E, Wang W, Kopetz S,
Maitra A
, Guerrero PA. Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype. Cancer Res. 2024 May 15; 84(10):1719-1732.
PMID:
38451249
; PMCID:
PMC11096054
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Maitra A
, Topol EJ. Early detection of pancreatic cancer and AI risk partitioning. Lancet. 2024 Apr 13; 403(10435):1438.
PMID:
38615682
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Fu J,
Ling J
, Li CF, Tsai CL, Yin W, Hou J, Chen P, Cao Y,
Kang Y
, Sun Y, Xia X, Jiang Z, Furukawa K, Lu Y, Wu M,
Huang Q
,
Yao J
, Hawke DH, Pan BF, Zhao J, Huang J, Wang H, Bahassi EIM, Stambrook PJ,
Huang P
,
Fleming JB
,
Maitra A
,
Tainer JA
,
Hung MC
, Lin C,
Chiao PJ
. Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer. Nat Commun. 2024 Apr 11; 15(1):3149.
PMID:
38605037
; PMCID:
PMC11009390
.
Citations:
1
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Baydogan S, Mohindroo C, Hasanov M, Montiel MF, Quesada P, Cazacu IM, Luzuriaga Chavez AA, Mork ME, Dong W, Feng L, You YN,
Arun B
, Vilar E, Brown P,
Katz MHG
, Chari ST,
Maitra A
,
Tamm EP
, Kim MP,
Bhutani MS
,
McAllister F
. New-onset diabetes is a predictive risk factor for pancreatic lesions in high-risk individuals: An observational cohort study. Endosc Ultrasound. 2024 Mar-Apr; 13(2):83-88.
PMID:
38947744
; PMCID:
PMC11213578
.
Citations:
Stangis MM, Chen Z, Min J, Glass SE, Jackson JO, Radyk MD, Hoi XP, Brennen WN, Yu M, Dinh HQ, Coffey RJ, Shrubsole MJ, Chan KS, Grady WM, Yegnasubramanian S, Lyssiotis CA,
Maitra A
, Halberg RB, Dey N, Lau KS. The Hallmarks of Precancer. Cancer Discov. 2024 Apr 04; 14(4):683-689.
PMID:
38571435
; PMCID:
PMC11170686
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Ho IL, Li CY, Wang F, Zhao L, Liu J, Yen EY, Dyke CA, Shah R, Liu Z, ?etin AO, Chu Y, Citron F, Attanasio S, Corti D, Darbaniyan F, Del Poggetto E, Loponte S, Liu J, Soeung M, Chen Z, Jiang S, Jiang H, Inoue A, Gao S, Deem A, Feng N,
Ying H
, Kim M, Giuliani V,
Genovese G
, Zhang J,
Futreal A
,
Maitra A
, Heffernan T, Wang L,
Do KA
, Gargiulo G,
Draetta G
, Carugo A, Lin R,
Viale A
. Clonal dominance defines metastatic dissemination in pancreatic cancer. Sci Adv. 2024 Mar 15; 10(11):eadd9342.
PMID:
38478609
.
Citations:
3
Fields:
Sci
Science
Translation:
Humans
Cells
Yang D, Sun X, Moniruzzaman R, Wang H, Citu C, Zhao Z,
Wistuba II
, Wang H,
Maitra A
, Chen Y. Genetic Deletion of Galectin-3 Inhibits Pancreatic Cancer Progression and Enhances the Efficacy of Immunotherapy. Gastroenterology. 2024 Jul; 167(2):298-314.
PMID:
38467382
.
Citations:
2
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Ben-Ami R, Wang QL, Zhang J, Supplee JG, Fahrmann JF, Lehmann-Werman R, Brais LK, Nowak J, Yuan C, Loftus M, Babic A, Irajizad E, Davidi T, Zick A, Hubert A, Neiman D, Piyanzin S, Gal-Rosenberg O, Horn A, Shemer R, Glaser B, Boos N, Jajoo K, Lee L, Clancy TE, Rubinson DA, Ng K, Chabot JA, Kastrinos F, Kluger M, Aguirre AJ, J?nne PA, Bardeesy N, Stanger B, O'Hara MH, Till J,
Maitra A
, Carpenter EL, Bullock AJ, Genkinger J,
Hanash SM
, Paweletz CP, Dor Y, Wolpin BM. Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer. Gut. 2024 03 07; 73(4):639-648.
PMID:
38123998
; PMCID:
PMC10958271
.
Citations:
6
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Trinh VQ, Ankenbauer KE, Liu J, Batardiere M, Maurer HC, Copeland C, Wong J, Ben-Levy O, Torbit SM, Jarvis B, Revetta F, Ivanov S, Jyotsana N, Makino Y, Ruelas AM, Means AL,
Maitra A
, Tan MCB, DelGiorno KE. Oncogenic GNAS drives a gastric pylorus program in intraductal papillary mucinous neoplasms of the pancreas. bioRxiv. 2024 Feb 28.
PMID:
38464029
; PMCID:
PMC10925208
.
Citations:
Wei D
, Wang L,
Zuo X
,
Maitra A
,
Bresalier RS
. A Small Molecule with Big Impact: MRTX1133 Targets the KRASG12D Mutation in Pancreatic Cancer. Clin Cancer Res. 2024 02 16; 30(4):655-662.
PMID:
37831007
; PMCID:
PMC10922474
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Rodriguez NJ, Furniss CS, Yurgelun MB, Ukaegbu C, Constantinou PE, Fortes I, Caruso A, Schwartz AN, Stopfer JE, Kenner B, Nelson SH, Okumura S, Zhou AY, Coffin TB, Uno H, Horiguchi M, Ocean AJ,
McAllister F
, Lowy AM, Klein AP, Madlensky L, Petersen GM, Garber JE, Lippman SM, Goggins MG,
Maitra A
, Syngal S, Underhill-Blazey M. A Randomized Trial of Two Remote Health Care Delivery Models on the Uptake of Genetic Testing and Impact on Patient-Reported Psychological Outcomes in Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, and Testing (GENERATE) Study. Gastroenterology. 2024 05; 166(5):872-885.e2.
PMID:
38320723
; PMCID:
PMC11034726
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Yousef A, Yousef M, Chowdhury S, Abdilleh K, Knafl M, Edelkamp P, Alfaro-Munoz K, Chacko R, Peterson J, Smaglo BG,
Wolff RA
,
Pant S
, Lee MS, Willis J,
Overman M
, Doss S, Matrisian L, Hurd MW, Snyder R,
Katz MHG
, Wang H,
Maitra A
, Shen JP,
Zhao D
. Impact of KRAS mutations and co-mutations on clinical outcomes in pancreatic ductal adenocarcinoma. NPJ Precis Oncol. 2024 Feb 03; 8(1):27.
PMID:
38310130
; PMCID:
PMC10838312
.
Citations:
8
Le?n-Letelier RA, Dou R, Vykoukal J, Yip-Schneider MT,
Maitra A
, Irajizad E, Wu R, Dennison JB,
Do KA
, Zhang J, Schmidt CM,
Hanash S
, Fahrmann JF. Contributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer. Clin Chem. 2024 01 04; 70(1):102-115.
PMID:
38175578
.
Citations:
4
Fields:
Che
Chemistry
Translation:
Humans
Abdilleh K, Khalid O, Ladnier D, Wan W, Seepo S, Rupp G, Corelj V, Worman ZF, Sain D, DiGiovanna J, Press B, Chandrashekhar S, Collisson E, Cui KY,
Maitra A
, Rejto PA, White KP, Matrisian L, Doss S. Pancreatic Cancer Action Network's SPARK: A Cloud-Based Patient Health Data and Analytics Platform for Pancreatic Cancer. JCO Clin Cancer Inform. 2024 01; 8:e2300119.
PMID:
38166233
; PMCID:
PMC10803046
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Maitra A
. Reaching your destination can require a diversion. Nat Cancer. 2024 Jan; 5(1):1.
PMID:
38172340
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Le?n-Letelier RA, Chen Y, Ballaro R, Irajizad E,
Do KA
,
Maitra A
, Zhang J, Schmidt CM, Fahrmann JF. A Blood-based Metabolite Signature for Personalized Risk Assessment of Pancreatic Cancer. J Cancer Immunol (Wilmington). 2024; 6(4):148-153.
PMID:
39713022
; PMCID:
PMC11661815
.
Citations:
Semaan A, Bernard V, Wong J, Makino Y, Swartzlander DB, Rajapakshe KI, Lee JJ, Officer A, Schmidt CM, Wu HH, Scaife CL, Affolter KE, Nachmanson D, Firpo MA, Yip-Schneider M, Lowy AM, Harismendy O,
Sen S
,
Maitra A
, Jakubek YA, Guerrero PA. Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project. Cancer Res Commun. 2023 10 10; 3(10):2062-2073.
PMID:
37721516
; PMCID:
PMC10563795
.
Citations:
Translation:
Humans
Chen Y,
Maitra A
. Anxiolytics cause anxiety in pancreatic cancer. Trends Cancer. 2023 11; 9(11):874-875.
PMID:
37778962
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Purushothaman A, Oliva-Ram?rez J, Treekitkarnmongkol W, Sankaran D, Hurd MW,
Putluri N
,
Maitra A
,
Haymaker C
,
Sen S
. Differential Effects of Pancreatic Cancer-Derived Extracellular Vesicles Driving a Suppressive Environment. Int J Mol Sci. 2023 Sep 27; 24(19).
PMID:
37834100
; PMCID:
PMC10572854
.
Citations:
Fields:
Bio
Biochemistry
Che
Chemistry
Mol
Molecular Biology
Translation:
Humans
Cells
Balasenthil S
, Liu S, Dai J, Bamlet WR, Petersen G, Chari ST,
Maitra A
, Chen N,
Sen S
, McNeill Killary A. Blood-based Migration Signature Biomarker Panel Discriminates Early Stage New Onset Diabetes related Pancreatic Ductal Adenocarcinoma from Type 2 Diabetes. Clin Chim Acta. 2023 Nov 01; 551:117567.
PMID:
37774897
.
Citations:
Fields:
Che
Chemistry
Translation:
Humans
Irajizad E, Kenney A, Tang T, Vykoukal J, Wu R, Murage E, Dennison JB, Sans M, Long JP, Loftus M, Chabot JA, Kluger MD, Kastrinos F, Brais L, Babic A, Jajoo K, Lee LS, Clancy TE, Ng K, Bullock A, Genkinger JM,
Maitra A
,
Do KA
, Yu B, Wolpin BM,
Hanash S
, Fahrmann JF. A blood-based metabolomic signature predictive of risk for pancreatic cancer. Cell Rep Med. 2023 09 19; 4(9):101194.
PMID:
37729870
; PMCID:
PMC10518621
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
Haldar SD, Vilar E,
Maitra A
, Zaidi N. Worth a Pound of Cure? Emerging Strategies and Challenges in Cancer Immunoprevention. Cancer Prev Res (Phila). 2023 09 01; 16(9):483-495.
PMID:
37001882
; PMCID:
PMC10548442
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
PH
Public Health
Mahadevan KK, McAndrews KM,
LeBleu VS
, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, Sugimoto H, Arian KA,
Ying H
, Barekatain Y, Sthanam LK, Kelly PJ,
Maitra A
, Heffernan TP,
Kalluri R
. KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T?cells. Cancer Cell. 2023 09 11; 41(9):1606-1620.e8.
PMID:
37625401
; PMCID:
PMC10785700
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Mahadevan KK,
LeBleu VS
, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M,
Ying H
,
Jain AK
,
DePinho RA
,
Maitra A
, McAndrews KM,
Kalluri R
. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T?cells. Dev Cell. 2023 09 11; 58(17):1562-1577.e8.
PMID:
37625403
; PMCID:
PMC10810082
.
Citations:
2
Fields:
Cel
Cell Biology
Emb
Embryology
Translation:
Humans
Animals
Cells
Sans M, Chen Y, Thege FI, Dou R, Min J, Yip-Schneider M, Zhang J, Wu R, Irajizad E, Makino Y, Rajapakshe KI, Hurd MW, Le?n-Letelier RA, Vykoukal J, Dennison JB, Do KA,
Wolff RA
, Guerrero PA, Kim MP, Schmidt CM,
Maitra A
,
Hanash S
, Fahrmann JF. Integrated spatial transcriptomics and lipidomics of precursor lesions of pancreatic cancer identifies enrichment of long chain sulfatide biosynthesis as an early metabolic alteration. bioRxiv. 2023 Aug 15.
PMID:
37645752
; PMCID:
PMC10462088
.
Citations:
Yousef A, Yousef M, Chowdhury S, Abdilleh K, Knafl M, Edelkamp P, Alfaro-Munoz K, Chacko R, Peterson J, Smaglo BG,
Wolff RA
,
Pant S
, Lee MS, Willis J,
Overman M
, Doss S, Matrisian L, Hurd MW, Snyder R,
Katz MHG
, Wang H,
Maitra A
, Shen JP,
Zhao D
. Impact of KRAS Mutations and Co-mutations on Clinical Outcomes in Pancreatic Ductal Adenocarcinoma. Res Sq. 2023 Aug 10.
PMID:
37609177
; PMCID:
PMC10441514
.
Citations:
Sans M, Makino Y, Min J, Rajapakshe KI, Yip-Schneider M, Schmidt CM, Hurd MW,
Burks JK
, Gomez JA, Thege FI, Fahrmann JF,
Wolff RA
, Kim MP, Guerrero PA,
Maitra A
. Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential. Cancer Discov. 2023 08 04; 13(8):1844-1861.
PMID:
37285225
; PMCID:
PMC10880589
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Colbert Maresso K,
Maitra A
,
Hawk ET
, Vilar E. From Premalignant Biology to Precision Interception: Connecting the Dots with a Curated Collection of Invited Articles. Cancer Prev Res (Phila). 2023 07 05; 16(7):365-367.
PMID:
37403656
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Liang TZ,
Katz MHG
, Prakash LR, Chatterjee D, Wang H, Kim M,
Tzeng CD
, Ikoma N,
Wolff RA
,
Zhao D
,
Koay EJ
,
Maitra A
, Kundu S, Wang H. Comparative Analyses of the Clinicopathologic Features of Short-Term and Long-Term Survivors of Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreatoduodenectomy. Cancers (Basel). 2023 Jun 18; 15(12).
PMID:
37370842
; PMCID:
PMC10296490
.
Citations:
Tan TH, Wang H, Moniruzzaman R, Li L, Ji B, Liu Y,
Zuo X
, Abbasgholizadeh R, Zhao J, Liu G, Wang R, Tang H, Sun R, Su X,
Maitra A
, Wang H. Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia. J Clin Invest. 2023 06 15; 133(12).
PMID:
37140994
; PMCID:
PMC10266776
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Animals
Chu Y, Dai E, Li Y, Han G, Pei G, Ingram DR, Thakkar K, Qin JJ, Dang M, Le X, Hu C, Deng Q, Sinjab A, Gupta P, Wang R, Hao D, Peng F, Yan X, Liu Y, Song S, Zhang S,
Heymach JV
, Reuben A, Elamin YY, Pizzi MP, Lu Y, Lazcano R, Hu J, Li M,
Curran M
,
Futreal A
,
Maitra A
,
Jazaeri AA
,
Ajani JA
, Swanton C, Cheng XD, Abbas HA, Gillison M,
Bhat K
,
Lazar AJ
, Green M, Litchfield K, Kadara H,
Yee C
, Wang L. Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance. Nat Med. 2023 Jun; 29(6):1550-1562.
PMID:
37248301
; PMCID:
PMC11421770
.
Citations:
26
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Tong YT, Lai Z,
Katz MHG
, Prakash LR, Wang H, Chatterjee D, Kim M,
Tzeng CD
, Lee JE, Ikoma N,
Rashid A
,
Wolff RA
,
Zhao D
,
Koay EJ
,
Maitra A
, Wang H. Prognosticators for Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel Therapy and Pancreatectomy. Cancers (Basel). 2023 May 04; 15(9).
PMID:
37174073
; PMCID:
PMC10177033
.
Citations:
1
Halbrook CJ, Lyssiotis CA, Pasca di Magliano M,
Maitra A
. Pancreatic cancer: Advances and challenges. Cell. 2023 04 13; 186(8):1729-1754.
PMID:
37059070
; PMCID:
PMC10182830
.
Citations:
17
Fields:
Cel
Cell Biology
Translation:
Humans
Cephas AT, Hwang WL,
Maitra A
, Parnas O, DelGiorno KE. It is better to light a candle than to curse the darkness: single-cell transcriptomics sheds new light on pancreas biology and disease. Gut. 2023 06; 72(6):1211-1219.
PMID:
36997301
; PMCID:
PMC10988578
.
Citations:
1
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Tovar DR, Rosenthal MH,
Maitra A
,
Koay EJ
. Potential of artificial intelligence in the risk stratification for and early detection of pancreatic cancer. Artif Intell Surg. 2023; 3(1):14-26.
PMID:
37124705
; PMCID:
PMC10141523
.
Citations:
Kolbinger FR, Bernard V, Lee JJ, Stephens BM, Branchi V,
Raghav KPS
,
Maitra A
, Guerrero PA, Semaan A. Significance of Distinct Liquid Biopsy Compartments in Evaluating Somatic Mutations for Targeted Therapy Selection in Cancer of Unknown Primary. J Gastrointest Cancer. 2023 Dec; 54(4):1276-1285.
PMID:
36862364
.
Citations:
Fields:
Gas
Gastroenterology
Neo
Neoplasms
Mahadevan KK, McAndrews KM,
LeBleu VS
, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA,
Kim MP
, Feng N, Lopez AM, Guerrero PA, Sugimoto H, Arian KA, Ying H, Barekatain Y, Kelly PJ,
Maitra A
, Heffernan TP,
Kalluri R
. Oncogenic Kras G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 + T cells dependent manner. bioRxiv. 2023 Feb 18.
PMID:
36824971
; PMCID:
PMC9948969
.
Citations:
Sohn AJ, Taherian M,
Katz MHG
, Prakash LR, Chatterjee D, Wang H, Kim M,
Tzeng CD
, Lee JE, Ikoma N,
Rashid A
,
Wolff RA
, Zhao D,
Koay EJ
, Sun R,
Maitra A
, Wang H. Integrated Pathologic Score Effectively Stratifies Patients With Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreaticoduodenectomy. Am J Surg Pathol. 2023 04 01; 47(4):421-430.
PMID:
36746143
; PMCID:
PMC10023386
.
Citations:
3
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Chen W, Butler RK, Lustigova E, Chari ST,
Maitra A
, Rinaudo JA, Wu BU. Risk Prediction of Pancreatic Cancer in Patients With Recent-onset Hyperglycemia: A Machine-learning Approach. J Clin Gastroenterol. 2023 01 01; 57(1):103-110.
PMID:
35470312
; PMCID:
PMC9585151
.
Citations:
Fields:
Gas
Gastroenterology
Gulhati P, Schalck A, Jiang S, Shang X, Wu CJ, Hou P, Ruiz SH, Soto LS, Parra E, Ying H, Han J, Dey P, Li J, Deng P, Sei E, Maeda DY, Zebala JA, Spring DJ, Kim M, Wang H,
Maitra A
, Moore D, Clise-Dwyer K, Wang YA,
Navin NE
,
DePinho RA
. Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer. Nat Cancer. 2023 01; 4(1):62-80.
PMID:
36585453
; PMCID:
PMC9925045
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kang Y, Deng J, Ling J, Li X, Chiang YJ,
Koay EJ
, Wang H,
Burks JK
,
Chiao PJ
, Hurd MW,
Bhutani MS
, Lee JH,
Weston BR
,
Maitra A
, Ikoma N,
Tzeng CD
, Lee JE,
DePinho RA
,
Wolff RA
,
Pant S
,
McAllister F
,
Katz MH
,
Fleming JB
, Kim MP. 3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma. J Clin Invest. 2022 12 15; 132(24).
PMID:
36282600
; PMCID:
PMC9753992
.
Citations:
2
Fields:
Med
Medicine (General)
Translation:
Humans
Amit M,
Maitra A
. The Boring Schwann Cells: Tumor Me-TAST-asis along Nerves. Cancer Discov. 2022 10 05; 12(10):2240-2243.
PMID:
36196575
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Schalck A, Sakellariou-Thompson D, Sei E, Hughes TG, Reuben A, Bai S, Hu M, Kumar T, Hurd MW,
Katz MHG
,
Tzeng CD
,
Pant S
,
Javle M
,
Fogelman DR
,
Maitra A
,
Haymaker CL
,
Kim MP
,
Navin NE
,
Bernatchez C
, Forget MA. Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer. Cancer Discov. 2022 10 05; 12(10):2330-2349.
PMID:
35849783
; PMCID:
PMC9547957
.
Citations:
Fields:
Neo
Neoplasms
Li CY, Rajapakshe KI,
Maitra A
. Integrative transcriptomic analysis identifies a novel gene signature to predict prognosis of pancreatic cancer in different subtypes. Pancreatology. 2022 Nov; 22(7):965-972.
PMID:
36008214
.
Citations:
Thege FI, Rupani DN, Barathi BB, Manning SL,
Maitra A
,
Rhim AD
, W?rmann SM. A Programmable In Vivo CRISPR Activation Model Elucidates the Oncogenic and Immunosuppressive Functions of MYC in Lung Adenocarcinoma. Cancer Res. 2022 08 03; 82(15):2761-2776.
PMID:
35666804
; PMCID:
PMC9357118
.
Citations:
Fields:
Neo
Neoplasms
Mohindroo C, De Jesus-Acosta A, Yurgelun MB,
Maitra A
, Mork M,
McAllister F
. The Evolving Paradigm of Germline Testing in Pancreatic Ductal Adenocarcinoma and Implications for Clinical Practice. Surg Pathol Clin. 2022 Sep; 15(3):491-502.
PMID:
36049831
.
Citations:
Zhang Y, Chen X, Wang H, Gordon-Mitchell S, Sahu S, Bhagat TD, Choudhary G, Aluri S, Pradhan K, Sahu P, Carbajal M, Zhang H, Agarwal B, Shastri A, Martell R, Starczynowski D, Steidl U,
Maitra A
, Verma A. Correction: Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer. J Hematol Oncol. 2022 Jul 26; 15(1):100.
PMID:
35883108
; PMCID:
PMC9327144
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Monberg ME, Geiger H, Lee JJ, Sharma R, Semaan A, Bernard V, Wong J, Wang F, Liang S, Swartzlander DB, Stephens BM,
Katz MHG
, Chen K, Robine N, Guerrero PA,
Maitra A
. Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution. Nat Commun. 2022 06 25; 13(1):3652.
PMID:
35752636
; PMCID:
PMC9233687
.
Citations:
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Cao S, Wang JR, Ji S, Yang P,
Dai Y
, Guo S,
Montierth MD
, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA,
Efstathiou E
, Lim B,
Viale A
, Zhang J, Nykter M,
Czerniak BA
, Brown PH, Swanton C, Msaouel P,
Maitra A
, Kopetz S, Campbell P, Speed TP, Boutros PC, Zhu H, Urbanucci A, Demeulemeester J, Van Loo P, Wang W. Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. Nat Biotechnol. 2022 11; 40(11):1624-1633.
PMID:
35697807
; PMCID:
PMC9646498
.
Citations:
Fields:
Bio
Biotechnology
Wu BU, Lustigova E, Chen Q, Dong EY,
Maitra A
, Chari ST,
Feng Z
, Rinaudo JA, Matrisian LM, Parker RA, Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Imaging of the Pancreas in New-Onset Diabetes: A Prospective Pilot Study. Clin Transl Gastroenterol. 2022 06 01; 13(6):e00478.
PMID:
35333778
; PMCID:
PMC9236602
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Wang CX, Elganainy D, Zaid MM, Butner JD, Agrawal A, Nizzero S,
Minsky BD
, Holliday EB,
Taniguchi CM
, Smith GL, Koong AC, Herman JM,
Das P
,
Maitra A
, Wang H,
Wolff RA
,
Katz MHG
, Crane CH, Cristini V,
Koay EJ
. Mass Transport Model of Radiation Response: Calibration and Application to Chemoradiation for Pancreatic Cancer. Int J Radiat Oncol Biol Phys. 2022 09 01; 114(1):163-172.
PMID:
35643254
; PMCID:
PMC10042520
.
Citations:
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Zhang Y, Chen X, Wang H, Gordon-Mitchell S, Sahu S, Bhagat TD, Choudhary G, Aluri S, Pradhan K, Sahu P, Carbajal M, Zhang H, Agarwal B, Shastri A, Martell R, Starczynowski D, Steidl U,
Maitra A
, Verma A. Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer. J Hematol Oncol. 2022 05 23; 15(1):70.
PMID:
35606824
; PMCID:
PMC9128118
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Hernandez S, Parra ER, Uraoka N, Tang X, Shen Y, Qiao W, Jiang M, Zhang S, Mino B, Lu W, Pandurengan R,
Haymaker C
, Affolter K, Scaife CL, Yip-Schneider M, Schmidt CM, Firpo MA, Mulvihill SJ,
Koay EJ
, Wang H,
Wistuba II
,
Maitra A
, Solis LM,
Sen S
. Diminished Immune Surveillance during Histologic Progression of Intraductal Papillary Mucinous Neoplasms Offers a Therapeutic Opportunity for Cancer Interception. Clin Cancer Res. 2022 05 02; 28(9):1938-1947.
PMID:
35491652
; PMCID:
PMC9069801
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Hosein AN, Dougan SK, Aguirre AJ,
Maitra A
. Translational advances in pancreatic ductal adenocarcinoma therapy. Nat Cancer. 2022 03; 3(3):272-286.
PMID:
35352061
.
Citations:
3
Translation:
Humans
Kasliwal S, Baydogan S, Harrison D, Mork M,
Maitra A
,
Mcallister F
. Implementation of a Video-based Remote Germline Testing for Individuals With Pancreatic Ductal Adenocarcinoma. Gastroenterology. 2022 07; 163(1):316-318.e1.
PMID:
35339459
; PMCID:
PMC9245458
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Garcia Garcia CJ, Huang Y, Fuentes NR, Turner MC, Monberg ME, Lin D, Nguyen ND, Fujimoto TN, Zhao J, Lee JJ, Bernard V, Yu M, Delahoussaye AM, Jimenez Sacarello I, Caggiano EG, Phan JL, Deorukhkar A, Molkentine JM, Saur D,
Maitra A
,
Taniguchi CM
. Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment. Gastroenterology. 2022 06; 162(7):2018-2031.
PMID:
35216965
; PMCID:
PMC9278556
.
Citations:
2
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Alam A, Levanduski E, Denz P, Villavicencio HS, Bhatta M, Alhorebi L, Zhang Y, Gomez EC, Morreale B, Senchanthisai S, Li J, Turowski SG, Sexton S, Sait SJ, Singh PK, Wang J,
Maitra A
, Kalinski P,
DePinho RA
, Wang H, Liao W, Abrams SI, Segal BH, Dey P. Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer. Cancer Cell. 2022 02 14; 40(2):153-167.e11.
PMID:
35120601
; PMCID:
PMC8847236
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Shah P, Frank ML, Jiang P, Sakellariou-Thompson D, Federico L, Khairullah R, Neutzler CA,
Wistuba I
, Chow CB, Long Y,
Fujimoto J
,
Lin SY
,
Maitra A
, Negrao MV, Mitchell KG,
Weissferdt A
,
Vaporciyan AA
, Cascone T,
Roth JA
, Zhang J,
Sepesi B
,
Gibbons DL
,
Heymach JV
,
Haymaker CL
, McGrail DJ, Reuben A,
Bernatchez C
, Forget MA. Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes. J Immunother Cancer. 2022 02; 10(2).
PMID:
35110355
; PMCID:
PMC8811607
.
Citations:
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Menter DG
,
Afshar-Kharghan V
, Shen JP, Martch SL,
Maitra A
, Kopetz S, Honn KV,
Sood AK
. Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective. Cancer Metastasis Rev. 2022 03; 41(1):147-172.
PMID:
35022962
; PMCID:
PMC8754476
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Bagley AF, Ludmir EB,
Maitra A
,
Minsky BD
, Li Smith G,
Das P
, Koong AC, Holliday EB,
Taniguchi CM
,
Katz MHG
,
Tamm EP
,
Wolff RA
,
Overman MJ
, Patel S,
Kim MP
,
Tzeng CD
, Ikoma N,
Bhutani MS
,
Koay EJ
. NBTXR3, a first-in-class radioenhancer for pancreatic ductal adenocarcinoma: Report of first patient experience. Clin Transl Radiat Oncol. 2022 Mar; 33:66-69.
PMID:
35097226
; PMCID:
PMC8783106
.
Citations:
2
Douglas JE, Liu S, Ma J,
Wolff RA
,
Pant S
,
Maitra A
,
Tamm EP
, Bhosale P,
Katz MHG
,
Varadhachary GR
,
Koay EJ
. PIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer. BMC Cancer. 2022 Jan 03; 22(1):14.
PMID:
34980020
; PMCID:
PMC8722115
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Hosein AN, Dangol G, Okumura T, Roszik J, Rajapakshe K, Siemann M, Zaid M, Ghosh B, Monberg M, Guerrero PA, Singhi A,
Haymaker CL
, Clevers H, Abou-Elkacem L, Woermann SM,
Maitra A
. Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma. Gastroenterology. 2022 04; 162(4):1303-1318.e18.
PMID:
34973294
; PMCID:
PMC8934289
.
Citations:
7
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Chen Y, Capello M, Rios Perez MV, Vykoukal JV, Roife D,
Kang Y
, Prakash LR, Katayama H, Irajizad E, Fleury A, Ferri-Borgogno S, Baluya DL, Dennison JB,
Do KA
, Fiehn O,
Maitra A
, Wang H,
Chiao PJ
,
Katz MHG
,
Fleming JB
,
Hanash SM
, Fahrmann JF. CES2 sustains HNF4a expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop. Mol Metab. 2022 02; 56:101426.
PMID:
34971802
; PMCID:
PMC8841288
.
Citations:
Fields:
Met
Metabolism
Translation:
Humans
Animals
Cells
Chari ST,
Maitra A
, Matrisian LM, Shrader EE, Wu BU, Kambadakone A, Zhao YQ, Kenner B, Rinaudo JAS, Srivastava S, Huang Y,
Feng Z
, Early Detection Initiative Consortium. Early Detection Initiative: A randomized controlled trial of algorithm-based screening in patients with new onset hyperglycemia and diabetes for early detection of pancreatic ductal adenocarcinoma. Contemp Clin Trials. 2022 02; 113:106659.
PMID:
34954100
; PMCID:
PMC8844106
.
Citations:
Fields:
Med
Medicine (General)
The
Therapeutics
Translation:
Humans
Gan Q, Roy-Chowdhuri S, Duose DY, Stewart JM, Coronel E,
Bhutani MS
, Lee JH,
Weston B
, Ge PS,
Ross WA
,
Maitra A
. Adequacy evaluation and use of pancreatic adenocarcinoma specimens for next-generation sequencing acquired by endoscopic ultrasound-guided FNA and FNB. Cancer Cytopathol. 2022 04; 130(4):275-283.
PMID:
34905283
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Acevedo Diaz AC, Kumari N, Govindaraju S, de la Cruz Bonilla M, San Lucas FA, Nguyen ND,
Piwnica-Worms H
,
Maitra A
,
Taniguchi CM
, Garc?a Garc?a CJ, Jim?nez Sacarello I. HIF2 Regulates Intestinal Wnt5a Expression. Front Oncol. 2021; 11:769385.
PMID:
34900719
; PMCID:
PMC8656274
.
Citations:
1
Zhang A, Thege FI, Cowan RW, Rupani DN, Wang R, Manning SL, Gates C, Wu W, Levin-Klein R, Rajapakshe KI, Yu M,
Multani AS
,
Kang Y
,
Taniguchi CM
,
Schlacher K
, Bellin MD,
Katz MHG
,
Kim MP
,
Fleming JB
, Gallinger S, Maddipati R, Harris RS, Notta F, Ross SR,
Maitra A
,
Rhim AD
, W?rmann SM. APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis. Nat Cancer. 2021 12; 2(12):1338-1356.
PMID:
35121902
.
Citations:
Translation:
Humans
Animals
Marcus R, Ferri-Borgogno S, Hosein A,
Foo WC
, Ghosh B, Zhao J, Rajapakshe K, Brugarolas J,
Maitra A
,
Gupta S
. Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma. Cancers (Basel). 2021 Nov 15; 13(22).
PMID:
34830866
; PMCID:
PMC8616431
.
Citations:
Furniss CS, Yurgelun MB, Ukaegbu C, Constantinou PE, Lafferty CC, Talcove-Berko ER, Schwartz AN, Stopfer JE, Underhill-Blazey M, Kenner B, Nelson SH, Okumura S, Law S, Zhou AY, Coffin TB, Rodriguez NJ, Uno H, Ocean AJ,
McAllister F
, Lowy AM, Lippman SM, Klein AP, Madlensky L, Petersen GM, Garber JE, Goggins MG,
Maitra A
, Syngal S. Novel Models of Genetic Education and Testing for Pancreatic Cancer Interception: Preliminary Results from the GENERATE Study. Cancer Prev Res (Phila). 2021 11; 14(11):1021-1032.
PMID:
34625409
; PMCID:
PMC8563400
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Del Poggetto E, Ho IL, Balestrieri C, Yen EY, Zhang S, Citron F, Shah R, Corti D, Diaferia GR, Li CY, Loponte S, Carbone F, Hayakawa Y, Valenti G, Jiang S, Sapio L, Jiang H, Dey P, Gao S, Deem AK, Yao W,
Ying H
,
Rhim AD
,
Genovese G
, Heffernan TP,
Maitra A
, Wang TC, Wang L,
Draetta GF
, Carugo A, Natoli G,
Viale A
, Rose-John S. Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis. Science. 2021 Sep 17; 373(6561):eabj0486.
PMID:
34529467
; PMCID:
PMC9733946
.
Citations:
9
Fields:
Sci
Science
Translation:
Animals
Cells
Trikudanathan G, Lou E,
Maitra A
, Majumder S. Early detection of pancreatic cancer: current state and future opportunities. Curr Opin Gastroenterol. 2021 09 01; 37(5):532-538.
PMID:
34387255
; PMCID:
PMC8494382
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Singh K, Pruski M, Bland R, Younes M, Guha S, Thosani N,
Maitra A
, Cash BD,
McAllister F
,
Logsdon CD
, Chang JT, Bailey-Lundberg JM. Correction to: Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer. Lab Invest. 2021 Sep; 101(9):1304.
PMID:
34079044
; PMCID:
PMC8367812
.
Citations:
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Lee JJ, Bernard V, Semaan A, Monberg ME, Huang J, Stephens BM, Lin D, Rajapakshe KI,
Weston BR
,
Bhutani MS
,
Haymaker CL
,
Bernatchez C
,
Taniguchi CM
,
Maitra A
, Guerrero PA. Elucidation of Tumor-Stromal Heterogeneity and the Ligand-Receptor Interactome by Single-Cell Transcriptomics in Real-world Pancreatic Cancer Biopsies. Clin Cancer Res. 2021 11 01; 27(21):5912-5921.
PMID:
34426439
; PMCID:
PMC8563410
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tong YT, Wang H, Wei D, Prakash LR, Kim M,
Tzeng CD
, Lee JE,
Rashid A
,
Koay EJ
,
Wolff RA
,
Maitra A
,
Katz MH
, Wang H. GRP78 expression and prognostic significance in patients with pancreatic ductal adenocarcinoma treated with neoadjuvant therapy versus surgery first. Pancreatology. 2021 Oct; 21(7):1378-1385.
PMID:
34429247
; PMCID:
PMC8541920
.
Citations:
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Giuliani V, Miller MA, Liu CY, Hartono SR, Class CA, Bristow CA, Suzuki E, Sanz LA, Gao G, Gay JP, Feng N, Rose JL, Tomihara H, Daniele JR, Peoples MD, Bardenhagen JP, Geck Do MK, Chang QE, Vangamudi B, Vellano C,
Ying H
, Deem AK,
Do KA
,
Genovese G
, Marszalek JR, Kovacs JJ, Kim M,
Fleming JB
, Guccione E,
Viale A
,
Maitra A
, Emilia Di Francesco M, Yap TA, Jones P,
Draetta G
, Carugo A, Chedin F, Heffernan TP. PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma. Nat Commun. 2021 07 30; 12(1):4626.
PMID:
34330913
; PMCID:
PMC8324870
.
Citations:
7
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Horsley AR, Belcher J, Bayfield K, Bianco B, Cunningham S, Fullwood C, Jones A, Shawcross A, Smith JA,
Maitra A
, Gilchrist FJ. Longitudinal assessment of lung clearance index to monitor disease progression in children and adults with cystic fibrosis. Thorax. 2022 04; 77(4):357-363.
PMID:
34301741
; PMCID:
PMC8938654
.
Citations:
Fields:
Pul
Pulmonary Medicine
Translation:
Humans
Han J,
DePinho RA
,
Maitra A
. Single-cell RNA sequencing in pancreatic cancer. Nat Rev Gastroenterol Hepatol. 2021 07; 18(7):451-452.
PMID:
34040169
; PMCID:
PMC8819738
.
Citations:
3
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Hambarde S, Tsai CL, Pandita RK, Bacolla A,
Maitra A
, Charaka V, Hunt CR, Kumar R, Limbo O, Le Meur R, Chazin WJ, Tsutakawa SE, Russell P,
Schlacher K
, Pandita TK,
Tainer JA
. EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Mol Cell. 2021 07 15; 81(14):2989-3006.e9.
PMID:
34197737
; PMCID:
PMC8720176
.
Citations:
8
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Chu Y, Pudakalakatti S, Hsieh KL, Salmon D, Dutta P,
Millward NZ
, Lurie E,
Millward S
,
McAllister F
,
Maitra A
,
Sen S
,
Killary A
, Zhang J, Jiang X,
Bhattacharya PK
, Shams S, Enriquez JS. Hyperpolarized Magnetic Resonance and Artificial Intelligence: Frontiers of Imaging in Pancreatic Cancer. JMIR Med Inform. 2021 Jun 17; 9(6):e26601.
PMID:
34137725
; PMCID:
PMC8277399
.
Citations:
1
Butler SS, Date K, Okumura T, Lueck C, Ghosh B,
Maitra A
, Suh J. Membrane-bound MMP-14 protease-activatable adeno-associated viral vectors for gene delivery to pancreatic tumors. Gene Ther. 2022 04; 29(3-4):138-146.
PMID:
33958732
; PMCID:
PMC8571120
.
Citations:
1
Fields:
Gen
Genetics
The
Therapeutics
Translation:
Animals
Cells
Dittmar RL, Liu S, Tai MC, Rajapakshe K, Huang Y, Longton G, DeCapite C, Hurd MW, Paris PL, Kirkwood KS,
Coarfa C
,
Maitra A
, Brand RE,
Killary AM
,
Sen S
. Plasma miRNA Biomarkers in Limited Volume Samples for Detection of Early-stage Pancreatic Cancer. Cancer Prev Res (Phila). 2021 07; 14(7):729-740.
PMID:
33893071
; PMCID:
PMC8818322
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Kim MP
, Li X, Deng J, Zhang Y,
Dai B
, Allton KL, Hughes TG, Siangco C, Augustine JJ,
Kang Y
, McDaniel JM,
Xiong S
,
Koay EJ
,
McAllister F
, Bristow CA, Heffernan TP,
Maitra A
, Liu B,
Barton MC
, Wasylishen AR,
Fleming JB
,
Lozano G
. Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis. Cancer Discov. 2021 08; 11(8):2094-2111.
PMID:
33839689
; PMCID:
PMC8338884
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Zhao J, Soto LMS, Wang H,
Katz MH
, Prakash LR, Kim M,
Tzeng CD
, Lee JE,
Wolff RA
, Huang Y,
Wistuba II
,
Maitra A
, Wang H. Overexpression of CD73 in pancreatic ductal adenocarcinoma is associated with immunosuppressive tumor microenvironment and poor survival. Pancreatology. 2021 Aug; 21(5):942-949.
PMID:
33832821
; PMCID:
PMC8802341
.
Citations:
1
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Semaan A, Bernard V, Kim DU, Lee JJ, Huang J, Kamyabi N, Stephens BM, Qiao W,
Varadhachary GR
,
Katz MH
, Shen Y, San Lucas FA, Gascoyne P, Alvarez HA,
Maitra A
, Guerrero PA. Characterisation of circulating tumour cell phenotypes identifies a partial-EMT sub-population for clinical stratification of pancreatic cancer. Br J Cancer. 2021 06; 124(12):1970-1977.
PMID:
33785875
; PMCID:
PMC8185080
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kenner B, Chari ST, Kelsen D, Klimstra DS, Pandol SJ, Rosenthal M, Rustgi AK, Taylor JA, Yala A, Abul-Husn N, Andersen DK, Bernstein D, Canto MI, Eldar YC, Fishman EK, Fleshman J, Go VLW, Holt JM, Field B, Goldberg A, Hoos W, Iacobuzio-Donahue C, Li D, Lidgard G,
Maitra A
, Matrisian LM, Poblete S, Rothschild L, Sander C, Schwartz LH, Shalit U, Srivastava S, Wolpin B, Brunak S. Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review. Pancreas. 2021 03 01; 50(3):251-279.
PMID:
33835956
; PMCID:
PMC8041569
.
Citations:
7
Fields:
Gas
Gastroenterology
Translation:
Humans
Pitarresi JR, Norgard RJ, Chiarella AM, Suzuki K, Bakir B, Sahu V, Li J, Zhao J, Wengyn MD, Hsieh A, Kim IK, Zhang A, Lee V, Takano S, Miyahara Y, Ohtsuka M,
Maitra A
, Notta F, Stanger BZ, Rustgi AK, Marchand B, Sellin K, Kremer R. PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability. Cancer Discov. 2021 07; 11(7):1774-1791.
PMID:
33589425
; PMCID:
PMC8292165
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Bray JK, Dawlaty MM, Verma A,
Maitra A
. Roles and Regulations of TET Enzymes in Solid Tumors. Trends Cancer. 2021 07; 7(7):635-646.
PMID:
33468438
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Fahrmann JF, Schmidt CM, Mao X, Irajizad E, Loftus M, Zhang J, Patel N, Vykoukal J, Dennison JB, Long JP,
Do KA
, Zhang J, Chabot JA, Kluger MD, Kastrinos F, Brais L, Babic A, Jajoo K, Lee LS, Clancy TE, Ng K, Bullock A, Genkinger J, Yip-Schneider MT,
Maitra A
, Wolpin BM,
Hanash S
. Lead-Time Trajectory of CA19-9 as an Anchor Marker for Pancreatic Cancer Early Detection. Gastroenterology. 2021 03; 160(4):1373-1383.e6.
PMID:
33333055
; PMCID:
PMC8783758
.
Citations:
14
Fields:
Gas
Gastroenterology
Translation:
Humans
PH
Public Health
Zhang Y, Chandra V, Riquelme Sanchez E, Dutta P, Quesada PR, Rakoski A, Zoltan M, Arora N, Baydogan S, Horne W,
Burks J
, Xu H, Hussain P, Wang H,
Gupta S
,
Maitra A
, Bailey JM,
Moghaddam SJ
, Banerjee S, Sahin I,
Bhattacharya P
,
McAllister F
. Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer. J Exp Med. 2020 12 07; 217(12).
PMID:
32860704
; PMCID:
PMC7953739
.
Citations:
49
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Zaid M, Widmann L, Dai A, Sun K, Zhang J, Zhao J, Hurd MW,
Varadhachary GR
,
Wolff RA
,
Maitra A
,
Katz MHG
, Herman JM, Wang H, Knopp MV, Williams TM, Bhosale P,
Tamm EP
,
Koay EJ
. Predictive Modeling for Voxel-Based Quantification of Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma (PDAC): A Multi-Institutional Study. Cancers (Basel). 2020 Dec 05; 12(12).
PMID:
33291471
; PMCID:
PMC7762105
.
Citations:
3
Zaid M, Elganainy D, Dogra P, Dai A, Widmann L,
Fernandes P
, Wang Z, Pelaez MJ, Ramirez JR, Singhi AD, Dasyam AK, Brand RE, Park WG, Rahmanuddin S, Rosenthal MH, Wolpin BM,
Khalaf N
, Goel A, Von Hoff DD,
Tamm EP
,
Maitra A
, Cristini V,
Koay EJ
. Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection. Front Oncol. 2020; 10:596931.
PMID:
33344245
; PMCID:
PMC7738633
.
Citations:
2
Wei D, Zaid MM,
Katz MH
, Prakash LR, Kim M,
Tzeng CD
, Lee JE, Agrawal A,
Rashid A
, Wang H,
Varadhachary G
,
Wolff RA
,
Tamm EP
, Bhosale PR,
Maitra A
,
Koay EJ
, Wang H. Clinicopathological correlation of radiologic measurement of post-therapy tumor size and tumor volume for pancreatic ductal adenocarcinoma. Pancreatology. 2021 Jan; 21(1):200-207.
PMID:
33221151
; PMCID:
PMC7855532
.
Citations:
1
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Semaan A, Bernard V, Lee JJ, Wong JW, Huang J, Swartzlander DB, Stephens BM, Monberg ME,
Weston BR
,
Bhutani MS
, Chang K,
Scheet PA
,
Maitra A
, Jakubek YA, Guerrero PA. Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real-World Endoscopic Aspiration Samples. Clin Cancer Res. 2021 02 15; 27(4):1082-1093.
PMID:
33188144
; PMCID:
PMC7887035
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Tomihara H, Carbone F, Perelli L, Huang JK, Soeung M, Rose JL, Robinson FS,
Lissanu Deribe Y
, Feng N, Takeda M, Inoue A, Poggetto ED, Deem AK,
Maitra A
, Msaouel P,
Tannir NM
,
Draetta GF
,
Viale A
, Heffernan TP, Bristow CA, Carugo A,
Genovese G
. Loss of ARID1A Promotes Epithelial-Mesenchymal Transition and Sensitizes Pancreatic Tumors to Proteotoxic Stress. Cancer Res. 2021 01 15; 81(2):332-343.
PMID:
33158812
; PMCID:
PMC8728103
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Capello M, Fahrmann JF, Rios Perez MV, Vykoukal JV, Irajizad E, Tripathi SC, Roife D, Bantis LE,
Kang Y
, Kundnani DL, Xu H, Prakash LR, Long JP, Katayama H, Fleury A, Ferri-Borgogno S, Baluya DL, Dennison JB, Aguilar-Bonavides C, Casabar JP, Celiktas M,
Do KA
, Fiehn O,
Maitra A
, Wang H,
Feng Z
,
Chiao PJ
,
Katz MH
,
Fleming JB
,
Hanash SM
. CES2 Expression in Pancreatic Adenocarcinoma Is Predictive of Response to Irinotecan and Is Associated With Type 2 Diabetes. JCO Precis Oncol. 2020 Nov; 4:426-436.
PMID:
35050739
; PMCID:
PMC10860959
.
Citations:
1
Fields:
Neo
Neoplasms
Bradley SD,
Talukder AH
, Lai I, Davis R, Alvarez H, Tiriac H, Zhang M, Chiu Y, Melendez B, Jackson KR, Katailiha A, Sonnemann HM, Li F, Kang Y, Qiao N, Pan BF, Lorenzi PL, Hurd M,
Mittendorf EA
, Peterson CB,
Javle M
, Bristow C, Kim M, Tuveson DA, Hawke D, Kopetz S,
Wolff RA
,
Hwu P
,
Maitra A
, Roszik J,
Yee C
, Liz?e G. Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers. Nat Commun. 2020 10 21; 11(1):5332.
PMID:
33087697
; PMCID:
PMC7577998
.
Citations:
5
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Cazacu IM, Semaan A, Stephens B, Swartzlander DB, Guerrero PA, Singh BS, Lungulescu CV, Danciulescu MM, Cherciu Harbiyeli IF, Streata I, Popescu C, Saftoiu A, Roy-Chowdhuri S,
Maitra A
,
Bhutani MS
. Diagnostic value of digital droplet polymerase chain reaction and digital multiplexed detection of single-nucleotide variants in pancreatic cytology specimens collected by EUS-guided FNA. Gastrointest Endosc. 2021 05; 93(5):1142-1151.e2.
PMID:
33058885
.
Citations:
1
Fields:
Dia
Diagnostic Imaging
Gas
Gastroenterology
The
Therapeutics
Translation:
Humans
Winnard PT, Bharti SK, Sharma RK, Krishnamachary B, Mironchik Y, Penet MF, Goggins MG,
Maitra A
, Kamel I, Horton KM, Jacobs MA, Bhujwalla ZM. Brain metabolites in cholinergic and glutamatergic pathways are altered by pancreatic cancer cachexia. J Cachexia Sarcopenia Muscle. 2020 12; 11(6):1487-1500.
PMID:
33006443
; PMCID:
PMC7749557
.
Citations:
3
Fields:
Neo
Neoplasms
Pat
Pathology
Translation:
Humans
Animals
Singh K, Pruski M, Bland R, Younes M, Guha S, Thosani N,
Maitra A
, Cash BD,
McAllister F
,
Logsdon CD
, Chang JT, Bailey-Lundberg JM. Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer. Lab Invest. 2021 02; 101(2):177-192.
PMID:
33009500
; PMCID:
PMC8172380
.
Citations:
8
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Animals
Ferri-Borgogno S, Barui S, McGee AM, Griffiths T,
Singh PK
, Piett CG, Ghosh B, Bhattacharyya S, Singhi A, Pradhan K, Verma A, Nagel Z,
Maitra A
,
Gupta S
. Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis. Cancers (Basel). 2020 Sep 21; 12(9).
PMID:
32967217
; PMCID:
PMC7564752
.
Citations:
2
Murphy AG, Zahurak M, Shah M, Weekes CD, Hansen A, Siu LL, Spreafico A, LoConte N, Anders NM, Miles T, Rudek MA, Doyle LA, Nelkin B,
Maitra A
, Azad NS, ETCTN-9231 Study Team. A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer. Clin Transl Sci. 2020 11; 13(6):1178-1188.
PMID:
32738099
; PMCID:
PMC7719383
.
Citations:
4
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Sharib J, Esserman L,
Koay EJ
,
Maitra A
, Shen Y, Kirkwood KS, Ozanne EM. Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective. Surgery. 2020 10; 168(4):601-609.
PMID:
32739138
; PMCID:
PMC8754171
.
Citations:
3
Fields:
Gen
General Surgery
Translation:
Humans
Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL,
Maitra A
, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR. Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma. CA Cancer J Clin. 2020 09; 70(5):375-403.
PMID:
32683683
; PMCID:
PMC7722002
.
Citations:
63
Fields:
Neo
Neoplasms
Translation:
Humans
Zhu Z, Achreja A, Meurs N, Animasahun O, Owen S, Mittal A, Parikh P, Lo TW, Franco-Barraza J, Shi J, Gunchick V, Sherman MH, Cukierman E, Pickering AM,
Maitra A
, Sahai V, Morgan MA, Nagrath S, Lawrence TS, Nagrath D. Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours. Nat Metab. 2020 08; 2(8):775-792.
PMID:
32694827
; PMCID:
PMC7438275
.
Citations:
31
Fields:
Met
Metabolism
Translation:
Humans
Cells
Liu Y, Kaur S, Huang Y, Fahrmann JF, Rinaudo JA,
Hanash SM
, Batra SK, Singhi AD, Brand RE,
Maitra A
, Haab BB. Biomarkers and Strategy to Detect Preinvasive and Early Pancreatic Cancer: State of the Field and the Impact of the EDRN. Cancer Epidemiol Biomarkers Prev. 2020 12; 29(12):2513-2523.
PMID:
32532830
; PMCID:
PMC7710622
.
Citations:
2
Fields:
Bio
Biochemistry
Epi
Epidemiology
Neo
Neoplasms
Translation:
Humans
Lee JJ, Kopetz S, Vilar E, Shen JP, Chen K,
Maitra A
. Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract. Genes (Basel). 2020 06 11; 11(6).
PMID:
32545271
; PMCID:
PMC7349178
.
Citations:
32
Fields:
Gen
Genetics
Translation:
Humans
Cells
PH
Public Health
Dutta P, Pando SC, Mascaro M, Riquelme E, Zoltan M, Zacharias NM,
Gammon ST
,
Piwnica-Worms D
, Pagel MD,
Sen S
,
Maitra A
, Shams S,
McAllister F
,
Bhattacharya PK
. Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy. Int J Mol Sci. 2020 May 25; 21(10).
PMID:
32466260
; PMCID:
PMC7279395
.
Citations:
3
Fields:
Bio
Biochemistry
Che
Chemistry
Mol
Molecular Biology
Translation:
Animals
Wang Z, Hausmann S, Lyu R, Li TM, Lofgren SM, Flores NM, Fuentes ME, Caporicci M, Yang Z, Meiners MJ, Cheek MA, Howard SA, Zhang L, Elias JE,
Kim MP
,
Maitra A
, Wang H, Bassik MC, Keogh MC, Sage J, Gozani O, Mazur PK. SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy. Cancer Cell. 2020 06 08; 37(6):834-849.e13.
PMID:
32442403
; PMCID:
PMC8187079
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Hosein AN, Brekken RA,
Maitra A
. Pancreatic cancer stroma: an update on therapeutic targeting strategies. Nat Rev Gastroenterol Hepatol. 2020 08; 17(8):487-505.
PMID:
32393771
; PMCID:
PMC8284850
.
Citations:
132
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Fahrmann JF, Mao X, Irajizad E, Katayama H, Capello M, Tanaka I, Kato T,
Wistuba II
,
Maitra A
,
Ostrin EJ
,
Hanash SM
, Vykoukal J. Plasma-Derived Extracellular Vesicles Convey Protein Signatures that Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas. Cancers (Basel). 2020 May 02; 12(5).
PMID:
32370304
; PMCID:
PMC7281335
.
Citations:
10
Maitra A
. Pancreatic cancer hidden in plain sight. Nature. 2020 05; 581(7806):34-35.
PMID:
32322029
.
Citations:
2
Fields:
Sci
Science
Translation:
Humans
Chari ST, Sharma A,
Maitra A
. Early Detection of Sporadic Pancreatic Ductal Adenocarcinoma: Problems, Promise, and Prospects. Ann Intern Med. 2020 04 21; 172(8):558-559.
PMID:
32176886
.
Citations:
2
Fields:
Int
Internal Medicine
Translation:
Humans
Ma Y
, Li J, Wang H, Chiu Y, Kingsley CV, Fry D, Delaney SN, Wei SC, Zhang J,
Maitra A
,
Yee C
. Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer. Gastroenterology. 2020 07; 159(1):306-319.e12.
PMID:
32179091
; PMCID:
PMC7387152
.
Citations:
21
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Kamyabi N, Abbasgholizadeh R,
Maitra A
, Ardekani A, Biswal SL, Grande-Allen KJ. Isolation and mutational assessment of pancreatic cancer extracellular vesicles using a microfluidic platform. Biomed Microdevices. 2020 03 11; 22(2):23.
PMID:
32162067
; PMCID:
PMC11108641
.
Citations:
10
Fields:
Bio
Biomedical Engineering
Translation:
Humans
Cells
Yao W,
Maitra A
, Ying H. Recent insights into the biology of pancreatic cancer. EBioMedicine. 2020 Mar; 53:102655.
PMID:
32139179
; PMCID:
PMC7118569
.
Citations:
41
Fields:
Gen
Genetics
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Horsley AR, Alrumuh A, Bianco B, Bayfield K, Tomlinson J, Jones A,
Maitra A
, Cunningham S, Smith J, Fullwood C, Pandyan A, Gilchrist FJ. Lung clearance index in healthy volunteers, measured using a novel portable system with a closed circuit wash-in. PLoS One. 2020; 15(2):e0229300.
PMID:
32097445
; PMCID:
PMC7041809
.
Citations:
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Dey P, Li J, Zhang J, Chaurasiya S, Strom A, Wang H, Liao WT, Cavallaro F, Denz P, Bernard V, Yen EY,
Genovese G
, Gulhati P, Liu J, Chakravarti D, Deng P, Zhang T, Carbone F, Chang Q,
Ying H
, Shang X, Spring DJ, Ghosh B,
Putluri N
,
Maitra A
, Wang YA,
DePinho RA
. Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment. Cancer Discov. 2020 04; 10(4):608-625.
PMID:
32046984
; PMCID:
PMC7125035
.
Citations:
48
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Bhutani MS
, Cazacu IM, Roy-Chowdhuri S,
Maitra A
, Pishvaian MJ. Upfront molecular profiling of pancreatic cancer patients - An idea whose time has come. Pancreatology. 2020 Apr; 20(3):391-393.
PMID:
32192904
.
Citations:
5
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Overman M
,
Javle M
, Davis RE, Vats P, Kumar-Sinha C, Xiao L, Mettu NB, Parra ER, Benson AB, Lopez CD, Munugalavadla V, Patel P, Tao L,
Neelapu S
,
Maitra A
. Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer. J Immunother Cancer. 2020 02; 8(1).
PMID:
32114502
; PMCID:
PMC7057435
.
Citations:
28
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
CT
Clinical Trials
Song X, Akasaka H, Wang H, Abbasgholizadeh R, Shin JH, Zang F, Chen J,
Logsdon CD
,
Maitra A
, Bean AJ, Wang H. Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer. J Biol Chem. 2020 02 21; 295(8):2348-2358.
PMID:
31959629
; PMCID:
PMC7039544
.
Citations:
4
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Cazacu IM, Luzuriaga Chavez AA,
Mendoza TR
, Qiao W, Singh BS, Bokhari RH, Saftoiu A, Lee JH,
Weston B
,
Stroehlein JR
,
Kim MP
, G Katz MH,
Maitra A
,
McAllister F
,
Bhutani MS
. Quality of life impact of EUS in patients at risk for developing pancreatic cancer. Endosc Ultrasound. 2020 Jan-Feb; 9(1):53-58.
PMID:
31552914
; PMCID:
PMC7038729
.
Citations:
1
De Jesus-Acosta A, Sugar EA, O'Dwyer PJ, Ramanathan RK, Von Hoff DD, Rasheed Z, Zheng L, Begum A, Anders R,
Maitra A
,
McAllister F
, Rajeshkumar NV, Yabuuchi S, de Wilde RF, Batukbhai B, Sahin I, Laheru DA. Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma. Br J Cancer. 2020 02; 122(4):498-505.
PMID:
31857726
; PMCID:
PMC7029016
.
Citations:
40
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Tu B, Yao J, Ferri-Borgogno S, Zhao J, Chen S, Wang Q, Yan L, Zhou X, Zhu C, Bang S, Chang Q, Bristow CA,
Kang Y
, Zheng H, Wang H,
Fleming JB
, Kim M, Heffernan TP,
Draetta GF
, Pan D,
Maitra A
, Yao W,
Gupta S
, Ying H. YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma. JCI Insight. 2019 11 01; 4(21).
PMID:
31557131
; PMCID:
PMC6948828
.
Citations:
24
Fields:
Med
Medicine (General)
Translation:
Humans
Bhagat TD, Von Ahrens D, Dawlaty M, Zou Y, Baddour J, Achreja A, Zhao H, Yang L, Patel B, Kwak C, Choudhary GS, Gordon-Mitchell S, Aluri S, Bhattacharyya S, Sahu S, Bhagat P, Yu Y, Bartenstein M, Giricz O, Suzuki M, Sohal D,
Gupta S
, Guerrero PA, Batra S, Goggins M, Steidl U, Greally J, Agarwal B, Pradhan K, Banerjee D, Nagrath D,
Maitra A
, Verma A. Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts. Elife. 2019 11 01; 8.
PMID:
31663852
; PMCID:
PMC6874475
.
Citations:
40
Fields:
Bio
Biology
Translation:
Humans
Animals
Cells
Wang M,
Estrella JS
,
Katz MH
, Kim M,
Rashid A
, Lee JE,
Maitra A
,
Wistuba II
,
Wolff RA
,
Varadhachary GR
, Wang H. Expression of Epithelial-Mesenchymal Transition Markers in Treated Pancreatic Ductal Adenocarcinoma. Pancreas. 2019 Nov/Dec; 48(10):1367-1372.
PMID:
31688603
; PMCID:
PMC6944196
.
Citations:
5
Fields:
Gas
Gastroenterology
Translation:
Humans
Pant S
,
Maitra A
, Yap TA. PARP inhibition - opportunities in pancreatic cancer. Nat Rev Clin Oncol. 2019 10; 16(10):595-596.
PMID:
31332344
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kamyabi N, Bernard V,
Maitra A
. Liquid biopsies in pancreatic cancer. Expert Rev Anticancer Ther. 2019 10; 19(10):869-878.
PMID:
31533487
; PMCID:
PMC6824837
.
Citations:
11
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Soragni A,
Maitra A
. Of scientists and tweets. Nat Rev Cancer. 2019 09; 19(9):479-480.
PMID:
31253855
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Koay EJ
,
Katz MHG
, Wang H, Wang X, Prakash L,
Javle M
,
Shroff R
,
Fogelman D
, Avila S, Zaid M, Elganainy D, Lee Y, Crane CH,
Krishnan S
,
Das P
,
Fleming JB
, Lee JE,
Tamm EP
, Bhosale P, Lee JH,
Weston B
,
Maitra A
,
Wolff RA
,
Varadhachary GR
. Computed Tomography-Based Biomarker Outcomes in a Prospective Trial of Preoperative FOLFIRINOX and Chemoradiation for Borderline Resectable Pancreatic Cancer. JCO Precis Oncol. 2019; 3.
PMID:
32914036
; PMCID:
PMC7446521
.
Citations:
6
Fields:
Neo
Neoplasms
Riquelme E, Zhang Y, Zhang L, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A,
Scheet P
, Xu H,
Hanash SM
, Feng L,
Burks JK
,
Do KA
, Peterson CB, Nejman D,
Tzeng CD
,
Kim MP
, Sears CL, Ajami N,
Petrosino J
, Wood LD,
Maitra A
, Straussman R,
Katz M
, White JR, Jenq R,
Wargo J
,
McAllister F
. Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes. Cell. 2019 08 08; 178(4):795-806.e12.
PMID:
31398337
; PMCID:
PMC7288240
.
Citations:
280
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Vence L, Bucktrout SL, Fernandez Curbelo I, Blando J, Smith BM, Mahne AE, Lin JC, Park T, Pascua E, Sai T, Chaparro-Riggers J,
Subudhi SK
, Scutti JB, Higa MG, Zhao H, Yadav SS,
Maitra A
,
Wistuba II
,
Allison JP
,
Sharma P
. Characterization and Comparison of GITR Expression in Solid Tumors. Clin Cancer Res. 2019 11 01; 25(21):6501-6510.
PMID:
31358539
; PMCID:
PMC6825542
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Yu M, Nguyen ND, Huang Y, Lin D, Fujimoto TN, Molkentine JM, Deorukhkar A,
Kang Y
, San Lucas FA, Fernandes CJ,
Koay EJ
,
Gupta S
,
Ying H
, Koong AC, Herman JM,
Fleming JB
,
Maitra A
,
Taniguchi CM
. Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer. JCI Insight. 2019 07 23; 5.
PMID:
31335325
; PMCID:
PMC6777817
.
Citations:
47
Fields:
Med
Medicine (General)
Translation:
Animals
Cells
Hosein AN, Huang H, Wang Z, Parmar K, Du W, Huang J,
Maitra A
, Olson E, Verma U, Brekken RA. Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution. JCI Insight. 2019 07 23; 5.
PMID:
31335328
; PMCID:
PMC6777805
.
Citations:
62
Fields:
Med
Medicine (General)
Translation:
Animals
Cells
Khorana AA, McKernin SE, Berlin J, Hong TS,
Maitra A
, Moravek C, Mumber M, Schulick R, Zeh HJ,
Katz MHG
. Potentially Curable Pancreatic Adenocarcinoma: ASCO Clinical Practice Guideline Update. J Clin Oncol. 2019 08 10; 37(23):2082-2088.
PMID:
31180816
.
Citations:
42
Fields:
Neo
Neoplasms
Translation:
Humans
Dutta P, Perez MR, Lee J, Kang Y, Pratt M, Salzillo TC, Weygand J, Zacharias NM,
Gammon ST
,
Koay EJ
, Kim M,
McAllister F
,
Sen S
,
Maitra A
,
Piwnica-Worms D
,
Fleming JB
,
Bhattacharya PK
. Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer. J Proteome Res. 2019 07 05; 18(7):2826-2834.
PMID:
31120258
.
Citations:
12
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Vicente D, Lee AJ, Hall CS,
Lucci A
, Lee JE,
Kim MP
,
Katz MHG
, Hurd MW,
Maitra A
, Rhim Md AD,
Tzeng CD
. Circulating Tumor Cells and Transforming Growth Factor Beta in Resected Pancreatic Adenocarcinoma. J Surg Res. 2019 11; 243:90-99.
PMID:
31170555
.
Citations:
5
Fields:
Gen
General Surgery
Translation:
Humans
Cells
CT
Clinical Trials
Fujimoto TN, Colbert LE, Huang Y, Molkentine JM, Deorukhkar A,
Baseler L
, Yu M, Lin D,
Gupta S
, Cabeceiras PK, Kingsley CV,
Tailor RC
,
Sawakuchi GO
,
Koay EJ
,
Piwnica-Worms H
,
Maitra A
,
Taniguchi CM
. Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer Res. 2019 05 01; 79(9):2327-2338.
PMID:
31043430
; PMCID:
PMC6666414
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Animals
PH
Public Health
Yao W,
Maitra A
. Hear Pancreatic Cancer Stem Cells ROR. Cell. 2019 04 18; 177(3):516-518.
PMID:
31002791
.
Citations:
2
Fields:
Cel
Cell Biology
Translation:
Humans
Shaw KRM,
Maitra A
. The Status and Impact of Clinical Tumor Genome Sequencing. Annu Rev Genomics Hum Genet. 2019 08 31; 20:413-432.
PMID:
30995147
.
Citations:
8
Fields:
Gen
Genetics
Gen
Genetics
Translation:
Humans
Fahrmann JF, Bantis LE, Capello M, Scelo G, Dennison JB, Patel N, Murage E, Vykoukal J, Kundnani DL, Foretova L, Fabianova E, Holcatova I, Janout V,
Feng Z
, Yip-Schneider M, Zhang J, Brand R,
Taguchi A
,
Maitra A
, Brennan P, Max Schmidt C,
Hanash S
. A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2019 04 01; 111(4):372-379.
PMID:
30137376
; PMCID:
PMC6449169
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Saluja A,
Maitra A
. Pancreatitis and Pancreatic Cancer. Gastroenterology. 2019 05; 156(7):1937-1940.
PMID:
30940522
.
Citations:
14
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Yao W, Rose JL, Wang W, Seth S, Jiang H,
Taguchi A
, Liu J, Yan L, Kapoor A,
Hou P
, Chen Z, Wang Q,
Nezi L
, Xu Z,
Yao J
, Hu B, Pettazzoni PF, Ho IL, Feng N, Ramamoorthy V, Jiang S, Deng P, Ma GJ, Den P,
Tan Z
, Zhang SX, Wang H, Wang YA, Deem AK,
Fleming JB
, Carugo A, Heffernan TP,
Maitra A
,
Viale A
,
Ying H
,
Hanash S
,
DePinho RA
,
Draetta GF
. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature. 2019 04; 568(7752):410-414.
PMID:
30918400
; PMCID:
PMC6661074
.
Citations:
53
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Singhi AD, George B, Greenbowe JR, Chung J, Suh J,
Maitra A
, Klempner SJ, Hendifar A, Milind JM, Golan T, Brand RE, Zureikat AH, Roy S, Schrock AB, Miller VA, Ross JS, Ali SM, Bahary N. Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers. Gastroenterology. 2019 06; 156(8):2242-2253.e4.
PMID:
30836094
.
Citations:
87
Fields:
Gas
Gastroenterology
Translation:
Humans
Maitra A
. Molecular envoys pave the way for pancreatic cancer to invade the liver. Nature. 2019 03; 567(7747):181-182.
PMID:
30850740
.
Citations:
8
Fields:
Sci
Science
Translation:
Humans
Cells
Wang EM, Akasaka H, Zhao J,
Varadhachary GR
, Lee JE,
Maitra A
,
Fleming JB
,
Hung MC
, Wang H,
Katz MHG
. Expression and Clinical Significance of Protein Kinase RNA-Like Endoplasmic Reticulum Kinase and Phosphorylated Eukaryotic Initiation Factor 2a in Pancreatic Ductal Adenocarcinoma. Pancreas. 2019 Mar; 48(3):323-328.
PMID:
30747823
; PMCID:
PMC6521859
.
Citations:
3
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Begum A, McMillan RH, Chang YT, Penchev VR, Rajeshkumar NV,
Maitra A
, Goggins MG, Eshelman JR, Wolfgang CL, Rasheed ZA, Matsui W. Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function. Pancreas. 2019 Mar; 48(3):329-334.
PMID:
30747824
; PMCID:
PMC6411432
.
Citations:
20
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P,
Su X
, Li L,
Lopez-Terrada D
, Rakheja D,
Lazar AJ
, Netto GJ, Rao P,
Maitra A
, Tripathi DN,
Walker CL
,
Karam JA
, Heffernan TP,
Viale A
, Roberts CWM, Msaouel P,
Tannir NM
,
Draetta GF
,
Genovese G
, Malouf GG, Sgambato A. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019 02 11; 35(2):204-220.e9.
PMID:
30753823
; PMCID:
PMC7876656
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ideno N, Yamaguchi H, Okumura T, Huang J, Brun MJ, Ho ML, Suh J,
Gupta S
,
Maitra A
, Ghosh B. A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination. Lab Invest. 2019 Jul; 99(8):1233-1244.
PMID:
30728464
.
Citations:
10
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Animals
Cells
Seth S, Li CY, Ho IL, Corti D, Loponte S, Sapio L, Del Poggetto E, Yen EY, Robinson FS, Peoples M, Karpinets T, Deem AK, Kumar T, Song X, Jiang S,
Kang Y
,
Fleming J
, Kim M, Zhang J,
Maitra A
, Heffernan TP, Giuliani V,
Genovese G
,
Futreal A
,
Draetta GF
, Carugo A,
Viale A
. Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors. Cell Rep. 2019 02 05; 26(6):1518-1532.e9.
PMID:
30726735
.
Citations:
28
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Singhi AD,
Koay EJ
, Chari ST,
Maitra A
. Early Detection of Pancreatic Cancer: Opportunities and Challenges. Gastroenterology. 2019 05; 156(7):2024-2040.
PMID:
30721664
; PMCID:
PMC6486851
.
Citations:
136
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Penchev VR, Chang YT, Begum A, Ewachiw T, Gocke C, Li J, McMillan RH, Wang Q, Anders R, Marchionni L,
Maitra A
, Uren A, Rasheed Z, Matsui W. Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma. Mol Cancer Res. 2019 04; 17(4):929-936.
PMID:
30655325
; PMCID:
PMC6445733
.
Citations:
4
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Capello M, Vykoukal JV, Katayama H, Bantis LE, Wang H, Kundnani DL, Aguilar-Bonavides C, Aguilar M, Tripathi SC, Dhillon DS, Momin AA, Peters H,
Katz MH
, Alvarez H, Bernard V, Ferri-Borgogno S, Brand R, Adler DG, Firpo MA, Mulvihill SJ,
Molldrem JJ
,
Feng Z
,
Taguchi A
,
Maitra A
,
Hanash SM
. Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity. Nat Commun. 2019 01 16; 10(1):254.
PMID:
30651550
; PMCID:
PMC6335434
.
Citations:
58
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Blando J, Sharma A, Higa MG, Zhao H, Vence L, Yadav SS, Kim J, Sepulveda AM, Sharp M,
Maitra A
,
Wargo J
,
Tetzlaff M
,
Broaddus R
,
Katz MHG
,
Varadhachary GR
,
Overman M
, Wang H,
Yee C
,
Bernatchez C
, Iacobuzio-Donahue C, Basu S,
Allison JP
,
Sharma P
. Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1692-1697.
PMID:
30635425
; PMCID:
PMC6358697
.
Citations:
115
Fields:
Sci
Science
Translation:
Humans
Cells
Staal B, Liu Y, Barnett D, Hsueh P, He Z, Gao C, Partyka K, Hurd MW, Singhi AD, Drake RR, Huang Y,
Maitra A
, Brand RE, Haab BB. The sTRA Plasma Biomarker: Blinded Validation of Improved Accuracy Over CA19-9 in Pancreatic Cancer Diagnosis. Clin Cancer Res. 2019 05 01; 25(9):2745-2754.
PMID:
30617132
; PMCID:
PMC7246054
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M,
Kim MP
,
Maitra A
, Wang H,
Wistuba II
, Porco JA, Bassik MC, Elias JE, Song J, Topisirovic I, Van Rechem C, Mazur PK, Gozani O. METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Cell. 2019 01 24; 176(3):491-504.e21.
PMID:
30612740
; PMCID:
PMC6499081
.
Citations:
38
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Lippman SM, Abate-Shen C, Colbert Maresso KL, Colditz GA, Dannenberg AJ, Davidson NE, Disis ML, DuBois RN, Szabo E, Giuliano AR, Hait WN, Lee JJ, Kensler TW, Kramer BS, Limburg P,
Maitra A
, Martinez ME, Rebbeck TR, Schmitz KH, Vilar E,
Hawk ET
. AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health. Cancer Prev Res (Phila). 2018 12; 11(12):735-778.
PMID:
30530635
; PMCID:
PMC10344465
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
PH
Public Health
Bernard V, Semaan A, Huang J, San Lucas FA, Mulu FC, Stephens BM, Guerrero PA, Huang Y, Zhao J, Kamyabi N,
Sen S
,
Scheet PA
,
Taniguchi CM
,
Kim MP
,
Tzeng CW
,
Katz MH
, Singhi AD,
Maitra A
, Alvarez HA. Single-Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression. Clin Cancer Res. 2019 Apr 01; 25(7):2194-2205.
PMID:
30385653
; PMCID:
PMC6445737
.
Citations:
111
Fields:
Neo
Neoplasms
Translation:
Humans
Goggins MG, Lippman SM, Constantinou PE, Jacks T, Petersen GM, Syngal S,
Maitra A
. Intercepting Pancreatic Cancer: Our Dream Team's Resolve to Stop Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1175-1176.
PMID:
30325853
; PMCID:
PMC6193263
.
Citations:
1
Fields:
Gas
Gastroenterology
Translation:
Humans
Maitra A
, Sharma A, Brand RE, Van Den Eeden SK, Fisher WE, Hart PA, Hughes SJ, Mather KJ, Pandol SJ, Park WG,
Feng Z
, Serrano J, Rinaudo JAS, Srivastava S, Chari ST, Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). A Prospective Study to Establish a New-Onset Diabetes Cohort: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1244-1248.
PMID:
30325864
; PMCID:
PMC6432934
.
Citations:
25
Fields:
Gas
Gastroenterology
Translation:
Humans
Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, Ramachandran V, Arumugam T, Niehrs C, Wang H,
Chiao P
,
Ling J
,
Curran MA
,
Maitra A
,
Hung MC
, Lee JE,
Logsdon CD
,
Hwang RF
. Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma. Sci Transl Med. 2018 10 24; 10(464).
PMID:
30355799
; PMCID:
PMC6752716
.
Citations:
8
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Gulhati P, Prakash L,
Katz MHG
, Wang X,
Javle M
,
Shroff R
,
Fogelman D
, Lee JE,
Tzeng CD
, Lee JH,
Weston B
,
Tamm E
, Bhosale P,
Koay EJ
,
Maitra A
, Wang H,
Wolff RA
,
Varadhachary GR
. First-Line Gemcitabine and Nab-Paclitaxel Chemotherapy for Localized Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol. 2019 Feb; 26(2):619-627.
PMID:
30324485
.
Citations:
5
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Bannon SA, Montiel MF, Goldstein JB, Dong W, Mork ME, Borras E, Hasanov M,
Varadhachary GR
,
Maitra A
,
Katz MH
, Feng L,
Futreal A
,
Fogelman DR
, Vilar E,
McAllister F
. High Prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic Cancer. Cancer Prev Res (Phila). 2018 11; 11(11):679-686.
PMID:
30274973
; PMCID:
PMC6343472
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Feldmann G, Brossart P,
Maitra A
. 'Diseases Desperate Grown by Desperate Appliance Are Relieved, or Not at all' - Towards Finding a Cure for Pancreatic Cancer, Where Do We Stand Today? Oncol Res Treat. 2018; 41(10):588-589.
PMID:
30286471
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Bernard V, Kim DU, San Lucas FA, Castillo J, Allenson K, Mulu FC, Stephens BM, Huang J, Semaan A, Guerrero PA, Kamyabi N, Zhao J, Hurd MW,
Koay EJ
,
Taniguchi CM
, Herman JM,
Javle M
,
Wolff R
,
Katz M
,
Varadhachary G
,
Maitra A
, Alvarez HA. Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer. Gastroenterology. 2019 01; 156(1):108-118.e4.
PMID:
30240661
; PMCID:
PMC6434712
.
Citations:
114
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Sharib JM, Fonseca AL, Swords DS, Jaradeh K, Bracci PM, Firpo MA, Hatcher S, Scaife CL, Wang H, Kim GE, Mulvihill SJ,
Maitra A
,
Koay EJ
, Kirkwood KS. Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: Do the 2017 International Consensus Guidelines improve clinical decision making? Surgery. 2018 12; 164(6):1178-1184.
PMID:
30170819
.
Citations:
9
Fields:
Gen
General Surgery
Translation:
Humans
Ideno N, Yamaguchi H, Ghosh B,
Gupta S
, Okumura T, Steffen DJ, Fisher CG, Wood LD, Singhi AD, Nakamura M, Gutkind JS,
Maitra A
. GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling. Gastroenterology. 2018 11; 155(5):1593-1607.e12.
PMID:
30142336
; PMCID:
PMC6219919
.
Citations:
30
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Koay EJ
, Lee Y, Cristini V, Lowengrub JS,
Kang Y
, Lucas FAS,
Hobbs BP
, Ye R, Elganainy D, Almahariq M, Amer AM, Chatterjee D, Yan H, Park PC, Rios Perez MV, Li D,
Garg N
, Reiss KA, Yu S, Chauhan A, Zaid M, Nikzad N,
Wolff RA
,
Javle M
,
Varadhachary GR
,
Shroff RT
,
Das P
, Lee JE, Ferrari M,
Maitra A
,
Taniguchi CM
,
Kim MP
, Crane CH,
Katz MH
, Wang H, Bhosale P,
Tamm EP
,
Fleming JB
. A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2018 12 01; 24(23):5883-5894.
PMID:
30082477
; PMCID:
PMC6279613
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Barua S, Solis L, Parra ER, Uraoka N, Jiang M, Wang H, Rodriguez-Canales J,
Wistuba I
,
Maitra A
,
Sen S
, Rao A. A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms. Cancer Inform. 2018; 17:1176935118782880.
PMID:
30013304
; PMCID:
PMC6043922
.
Citations:
16
Maitra A
. Severe Asthma: Challenges and Pitfalls in Management. Indian J Pediatr. 2018 Sep; 85(9):763-772.
PMID:
29736695
.
Citations:
1
Fields:
Ped
Pediatrics
Translation:
Humans
PH
Public Health
Mendt M, Kamerkar S, Sugimoto H, McAndrews KM, Wu CC, Gagea M, Yang S, Blanko EVR, Peng Q, Ma X, Marszalek JR,
Maitra A
,
Yee C
, Rezvani K,
Shpall E
,
LeBleu VS
,
Kalluri R
. Generation and testing of clinical-grade exosomes for pancreatic cancer. JCI Insight. 2018 04 19; 3(8).
PMID:
29669940
; PMCID:
PMC5931131
.
Citations:
203
Fields:
Med
Medicine (General)
Translation:
Animals
Cells
Riquelme E,
Maitra A
,
McAllister F
. Immunotherapy for Pancreatic Cancer: More Than Just a Gut Feeling. Cancer Discov. 2018 04; 8(4):386-388.
PMID:
29610286
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Animals
Zhang Y, Zoltan M, Riquelme E, Xu H, Sahin I, Castro-Pando S, Montiel MF, Chang K, Jiang Z,
Ling J
,
Gupta S
, Horne W, Pruski M, Wang H,
Sun SC
,
Lozano G
,
Chiao P
,
Maitra A
, Leach SD, Kolls JK, Vilar E, Wang TC, Bailey JM,
McAllister F
. Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells. Gastroenterology. 2018 07; 155(1):210-223.e3.
PMID:
29604293
; PMCID:
PMC6035075
.
Citations:
50
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Wang YN, Lee HH,
Chou CK
, Yang WH, Wei Y, Chen CT,
Yao J
, Hsu JL, Zhu C,
Ying H
,
Ye Y
, Wang WJ,
Lim SO
,
Xia W
, Ko HW, Liu X, Liu CG, Wu X, Wang H, Li D, Prakash LR,
Katz MH
, Kang Y, Kim M,
Fleming JB
,
Fogelman D
,
Javle M
,
Maitra A
,
Hung MC
. Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer. Cancer Cell. 2018 04 09; 33(4):752-769.e8.
PMID:
29606349
; PMCID:
PMC5893359
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Shah MY, Ferracin M, Pileczki V, Chen B, Redis R, Fabris L, Zhang X,
Ivan C
, Shimizu M, Rodriguez-Aguayo C, Dragomir M,
Van Roosbroeck K
, Almeida MI, Ciccone M, Nedelcu D,
Cortez MA
, Manshouri T, Calin S, Muftuoglu M, Banerjee PP, Badiwi MH,
Parker-Thornburg J
,
Multani A
,
Welsh JW
,
Estecio MR
,
Ling H
, Tomuleasa C, Dima D, Yang H, Alvarez H, You MJ, Radovich M,
Shpall E
, Fabbri M,
Rezvani K
, Girnita L, Berindan-Neagoe I,
Maitra A
,
Verstovsek S
, Fodde R,
Bueso-Ramos C
, Gagea M, Manero GG,
Calin GA
. Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations. Genome Res. 2018 04; 28(4):432-447.
PMID:
29567676
; PMCID:
PMC5880235
.
Citations:
32
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Fonseca AL, Kirkwood K,
Kim MP
,
Maitra A
,
Koay EJ
. Intraductal Papillary Mucinous Neoplasms of the Pancreas: Current Understanding and Future Directions for Stratification of Malignancy Risk. Pancreas. 2018 03; 47(3):272-279.
PMID:
29424809
; PMCID:
PMC5808987
.
Citations:
4
Fields:
Gas
Gastroenterology
Translation:
Humans
Wolff RA
, Wang-Gillam A, Alvarez H, Engle D, Hou S, Groff AF, San Lucas A, Bernard V, Allenson K, Castillo J, Kim D, Mulu F, Huang J, Stephens B,
Wistuba II
,
Katz M
,
Varadhachary G
, Park Y, Hicks J, Chinnaiyan A, Scampavia L, Spicer T, Gerhardinger C,
Maitra A
, Tuveson D, Rinn J,
Lizee G
,
Yee C
, Levine AJ, Tiriac H. Dynamic changes during the treatment of pancreatic cancer. Oncotarget. 2018 Mar 13; 9(19):14764-14790.
PMID:
29599906
; PMCID:
PMC5871077
.
Citations:
9
Fields:
Neo
Neoplasms
Amer AM, Zaid M, Chaudhury B, Elganainy D, Lee Y, Wilke CT, Cloyd J, Wang H,
Maitra A
,
Wolff RA
,
Varadhachary G
,
Overman MJ
, Lee JE,
Fleming JB
,
Tzeng CW
,
Katz MH
, Holliday EB,
Krishnan S
,
Minsky BD
, Herman JM,
Taniguchi CM
,
Das P
, Crane CH,
Le O
, Bhosale P,
Tamm EP
,
Koay EJ
. Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy. Cancer. 2018 04 15; 124(8):1701-1709.
PMID:
29370450
; PMCID:
PMC5891375
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Semaan A,
Maitra A
. Pancreatic cancer in 2017: Rebooting pancreatic cancer knowledge and treatment options. Nat Rev Gastroenterol Hepatol. 2018 02; 15(2):76-78.
PMID:
29317774
.
Citations:
6
Fields:
Gas
Gastroenterology
Translation:
Humans
Zhao J, Wang H, Hsiao CH,
Chow DS
,
Koay EJ
, Kang Y, Wen X, Huang Q, Ma Y,
Bankson JA
,
Ullrich SE
,
Overwijk W
,
Maitra A
,
Piwnica-Worms D
,
Fleming JB
, Li C. Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy. Biomaterials. 2018 03; 159:215-228.
PMID:
29331808
; PMCID:
PMC6203960
.
Citations:
26
Fields:
Bio
Biomedical Engineering
Translation:
Animals
Cells
Castillo J, Bernard V, San Lucas FA, Allenson K, Capello M, Kim DU, Gascoyne P, Mulu FC, Stephens BM, Huang J, Wang H, Momin AA,
Jacamo RO
, Katz M,
Wolff R
,
Javle M
,
Varadhachary G
,
Wistuba II
,
Hanash S
,
Maitra A
, Alvarez H. Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients. Ann Oncol. 2018 01 01; 29(1):223-229.
PMID:
29045505
; PMCID:
PMC6248757
.
Citations:
70
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ramanathan RK, Weiss GJ, Posner RG, Rajeshkumar NV, Jameson G, Aziz M, Hoering A, Bolejack V,
Maitra A
, Fulk M, Stites EC, Hlavacek WS, Gatalica Z, Xiu J, Hidalgo M, Von Hoff DD, Barrett MT. A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients. J Gastrointest Oncol. 2017 Dec; 8(6):925-935.
PMID:
29299351
; PMCID:
PMC5750179
.
Citations:
Ludwig KF, Du W, Sorrelle NB, Wnuk-Lipinska K, Topalovski M, Toombs JE, Cruz VH, Yabuuchi S, Rajeshkumar NV,
Maitra A
, Lorens JB, Brekken RA. Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer. Cancer Res. 2018 01 01; 78(1):246-255.
PMID:
29180468
; PMCID:
PMC5754222
.
Citations:
56
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Cloyd JM, Wang H, Egger ME,
Tzeng CD
, Prakash LR,
Maitra A
,
Varadhachary GR
,
Shroff R
,
Javle M
,
Fogelman D
,
Wolff RA
,
Overman MJ
,
Koay EJ
,
Das P
, Herman JM,
Kim MP
,
Vauthey JN
,
Aloia TA
,
Fleming JB
, Lee JE,
Katz MHG
. Association of Clinical Factors With a Major Pathologic Response Following Preoperative Therapy for Pancreatic Ductal Adenocarcinoma. JAMA Surg. 2017 Nov 01; 152(11):1048-1056.
PMID:
28700784
; PMCID:
PMC5710421
.
Citations:
26
Fields:
Gen
General Surgery
Translation:
Humans
Bhattacharyya S, Pradhan K, Campbell N, Mazdo J, Vasantkumar A, Maqbool S, Bhagat TD,
Gupta S
, Suzuki M, Yu Y, Greally JM, Steidl U, Bradner J, Dawlaty M, Godley L,
Maitra A
, Verma A. Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways. Genome Res. 2017 11; 27(11):1830-1842.
PMID:
28986391
; PMCID:
PMC5668941
.
Citations:
28
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Goldstein JB,
Halperin DM
, Wang H, Hejazi N,
Rashid A
,
Katz MH
, Lee JE,
Fleming JB
, Rodriguez-Canales J, Blando J,
Wistuba II
,
Maitra A
,
Wolff RA
,
Varadhachary GR
, Wang H, Nejati R. Prognostic Significance of Tumor-Infiltrating Lymphocytes in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Chemotherapy. Pancreas. 2017 10; 46(9):1180-1187.
PMID:
28902789
; PMCID:
PMC5790553
.
Citations:
21
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Sakellariou-Thompson D, Creasy C, Bernard V, Zhao L, Kim YU, Hurd MW, Uraoka N, Parra ER,
Kang Y
, Bristow CA, Rodriguez-Canales J,
Fleming JB
,
Varadhachary G
,
Javle M
,
Overman MJ
, Alvarez HA, Heffernan TP, Zhang J,
Hwu P
,
Maitra A
,
Haymaker C
,
Bernatchez C
, Forget MA. 4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer. Clin Cancer Res. 2017 Dec 01; 23(23):7263-7275.
PMID:
28947567
; PMCID:
PMC6097625
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Marcus R,
Maitra A
, Roszik J. Recent advances in genomic profiling of adenosquamous carcinoma of the pancreas. J Pathol. 2017 11; 243(3):271-272.
PMID:
28816351
.
Citations:
7
Fields:
Pat
Pathology
Translation:
Humans
Animals
Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, Thaiss CA, Reuben A, Livny J, Avraham R, Frederick DT, Ligorio M, Chatman K, Johnston SE, Mosher CM, Brandis A, Fuks G, Gurbatri C, Gopalakrishnan V, Kim M, Hurd MW,
Katz M
,
Fleming J
,
Maitra A
, Smith DA, Skalak M, Bu J, Michaud M, Trauger SA, Barshack I, Golan T, Sandbank J, Flaherty KT, Mandinova A, Garrett WS, Thayer SP, Ferrone CR, Huttenhower C, Bhatia SN, Gevers D,
Wargo JA
, Golub TR, Straussman R. Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science. 2017 09 15; 357(6356):1156-1160.
PMID:
28912244
; PMCID:
PMC5727343
.
Citations:
349
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, Falconi M, Doglioni C, Weiss MJ, Ahuja N, He J, Makary MA,
Maitra A
,
Hanash SM
, Dal Molin M, Wang Y, Li L, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Goggins MG, Hruban RH, Wolfgang CL, Klein AP, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Lennon AM. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10202-10207.
PMID:
28874546
; PMCID:
PMC5617273
.
Citations:
178
Fields:
Sci
Science
Translation:
Humans
Katz MH
,
Foo WC
, Sundar M, Wang H,
Varadhachary GR
,
Wolff RA
, Lee JE,
Maitra A
,
Fleming JB
,
Rashid A
, Wang H, Chatterjee D. Prognostic Significance of New AJCC Tumor Stage in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Therapy. Am J Surg Pathol. 2017 Aug; 41(8):1097-1104.
PMID:
28614206
; PMCID:
PMC5527751
.
Citations:
19
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Begum A, Ewachiw T, Jung C, Huang A, Norberg KJ, Marchionni L, McMillan R, Penchev V, Rajeshkumar NV,
Maitra A
, Wood L, Wang C, Wolfgang C, DeJesus-Acosta A, Laheru D, Shapiro IM, Padval M, Pachter JA, Weaver DT, Rasheed ZA, Matsui W. The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma. PLoS One. 2017; 12(7):e0180181.
PMID:
28692661
; PMCID:
PMC5503247
.
Citations:
41
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Rajeshkumar NV, Yabuuchi S, Pai SG, De Oliveira E, Kamphorst JJ, Rabinowitz JD, Hidalgo M,
Maitra A
, Dang CV, Tejero H, Al-Shahrour F. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017 Sep 15; 23(18):5639-5647.
PMID:
28611197
; PMCID:
PMC6540110
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
McAllister F
, Montiel MF, Uberoi GS, Uberoi AS,
Maitra A
,
Bhutani MS
. Current Status and Future Directions for Screening Patients at High Risk for Pancreatic Cancer. Gastroenterol Hepatol (N Y). 2017 May; 13(5):268-275.
PMID:
28656024
; PMCID:
PMC5479340
.
Citations:
9
Maitra A
. Slicing and Dicing Pancreatic Cancer Into Actionable Nuggets. J Natl Compr Canc Netw. 2017 05; 15(5):649-650.
PMID:
28476743
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Khorana AA, Mangu PB, Berlin J, Engebretson A, Hong TS,
Maitra A
, Mohile SG, Mumber M, Schulick R, Shapiro M, Urba S, Zeh HJ,
Katz MHG
. Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2017 Jul 10; 35(20):2324-2328.
PMID:
28398845
.
Citations:
50
Fields:
Neo
Neoplasms
Translation:
Humans
Allenson K, Castillo J, San Lucas FA, Scelo G, Kim DU, Bernard V, Davis G, Kumar T, Katz M,
Overman MJ
, Foretova L, Fabianova E, Holcatova I, Janout V,
Meric-Bernstam F
, Gascoyne P,
Wistuba I
,
Varadhachary G
, Brennan P,
Hanash S
, Li D,
Maitra A
, Alvarez H. High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients. Ann Oncol. 2017 04 01; 28(4):741-747.
PMID:
28104621
; PMCID:
PMC5834026
.
Citations:
149
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Capello M, Bantis LE, Scelo G, Zhao Y, Li P, Dhillon DS, Patel NJ, Kundnani DL, Wang H, Abbruzzese JL,
Maitra A
, Tempero MA, Brand R, Firpo MA, Mulvihill SJ,
Katz MH
, Brennan P,
Feng Z
,
Taguchi A
,
Hanash SM
. Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2017 04 01; 109(4).
PMID:
28376157
; PMCID:
PMC5441297
.
Citations:
59
Fields:
Neo
Neoplasms
Translation:
Humans
von Ahrens D, Bhagat TD, Nagrath D,
Maitra A
, Verma A. The role of stromal cancer-associated fibroblasts in pancreatic cancer. J Hematol Oncol. 2017 03 28; 10(1):76.
PMID:
28351381
; PMCID:
PMC5371211
.
Citations:
140
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Cells
Collisson EA,
Maitra A
. Pancreatic Cancer Genomics 2.0: Profiling Metastases. Cancer Cell. 2017 03 13; 31(3):309-310.
PMID:
28292434
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Liu Q, Stewart J, Wang H,
Rashid A
, Zhao J,
Katz MH
, Lee JE,
Fleming JB
,
Maitra A
,
Wolff RA
,
Varadhachary GR
,
Krishnan S
, Wang H. Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma. PLoS One. 2017; 12(2):e0171985.
PMID:
28187218
; PMCID:
PMC5302782
.
Citations:
11
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Genovese G
, Carugo A, Tepper J, Robinson FS, Li L, Svelto M,
Nezi L
, Corti D, Minelli R, Pettazzoni P, Gutschner T, Wu CC, Seth S, Akdemir KC, Leo E, Amin S, Molin MD,
Ying H
,
Kwong LN
,
Colla S
,
Takahashi K
, Ghosh P, Giuliani V,
Muller F
, Dey P, Jiang S, Garvey J, Liu CG, Zhang J, Heffernan TP, Toniatti C,
Fleming JB
, Goggins MG, Wood LD, Agaimy A,
Maitra A
, Roberts CW, Wang H,
Viale A
,
DePinho RA
,
Draetta GF
, Chin L, Sgambato A. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017 02 16; 542(7641):362-366.
PMID:
28178232
; PMCID:
PMC7609022
.
Citations:
53
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Maitra A
, Xie VK. Kr?ppel-Like Factor 4 Promotes Pancreatic Acinar-to-Ductal Metaplasia and Tumor Initiation. Pancreas. 2017 02; 46(2):139-142.
PMID:
28085752
.
Citations:
1
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Maitra A
, Berlin JD, Thota R. Preclinical Rationale for the Phase III Trials in Metastatic Pancreatic Cancer: Is Wishful Thinking Clouding Successful Drug Development for Pancreatic Cancer? Pancreas. 2017 02; 46(2):143-150.
PMID:
28085753
; PMCID:
PMC5242389
.
Citations:
8
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cloyd JM, Wang H,
Overman M
, Zhao J, Denbo J, Prakash L,
Kim MP
,
Shroff R
,
Javle M
,
Varadhachary GR
,
Fogelman D
,
Wolff RA
,
Koay EJ
,
Das P
,
Maitra A
,
Aloia TA
,
Vauthey JN
,
Fleming JB
, Lee JE,
Katz MHG
. Influence of Preoperative Therapy on Short- and Long-Term Outcomes of Patients with Adenocarcinoma of the Ampulla of Vater. Ann Surg Oncol. 2017 Jul; 24(7):2031-2039.
PMID:
28124275
.
Citations:
8
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Cullis J, Siolas D, Avanzi A, Barui S,
Maitra A
, Bar-Sagi D. Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer. Cancer Immunol Res. 2017 03; 5(3):182-190.
PMID:
28108630
; PMCID:
PMC5570452
.
Citations:
54
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Dey P, Baddour J,
Muller F
, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y,
Fleming J
, Satani N, Zhao D, Achreja A, Yang L, Lee J,
Chang E
,
Genovese G
,
Viale A
,
Ying H
,
Draetta G
,
Maitra A
, Wang YA, Nagrath D,
DePinho RA
. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017 02 02; 542(7639):119-123.
PMID:
28099419
; PMCID:
PMC5398413
.
Citations:
96
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Hanania AN
, Bantis LE,
Feng Z
, Wang H,
Tamm EP
,
Katz MH
,
Maitra A
,
Koay EJ
. Quantitative imaging to evaluate malignant potential of IPMNs. Oncotarget. 2016 Dec 27; 7(52):85776-85784.
PMID:
27588410
; PMCID:
PMC5349873
.
Citations:
43
Fields:
Neo
Neoplasms
Translation:
Humans
Katz MH
, Liu L, Sundar M, Wang H,
Varadhachary GR
,
Wolff RA
, Lee JE,
Maitra A
,
Fleming JB
,
Rashid A
, Wang H, Lee SM. Validation of a Proposed Tumor Regression Grading Scheme for Pancreatic Ductal Adenocarcinoma After Neoadjuvant Therapy as a Prognostic Indicator for Survival. Am J Surg Pathol. 2016 12; 40(12):1653-1660.
PMID:
27631521
; PMCID:
PMC5178828
.
Citations:
25
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Humphris JL, Patch AM, Nones K, Bailey PJ, Johns AL, McKay S, Chang DK, Miller DK, Pajic M, Kassahn KS, Quinn MC, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Stone A, Wilson PJ, Anderson M, Fink JL, Holmes O, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Mead RS, Xu Q, Wu J, Pinese M, Cowley MJ, Jones MD, Nagrial AM, Chin VT, Chantrill LA, Mawson A, Chou A, Scarlett CJ, Pinho AV, Rooman I, Giry-Laterriere M, Samra JS, Kench JG, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Jamieson NB, McKay CJ, Carter CR, Dickson EJ, Graham JS, Duthie F, Oien K, Hair J, Morton JP, Sansom OJ, Hruban RH,
Maitra A
, Iacobuzio-Donahue CA, Schulick RD, Wolfgang CL, Morgan RA, Lawlor RT, Rusev B, Corbo V, Salvia R, Cataldo I, Tortora G, Tempero MA, Australian Pancreatic Cancer Genome Initiative, Hofmann O, Eshleman JR, Scarpa A, Musgrove EA, Gill AJ, Pearson JV, Grimmond SM, Waddell N, Biankin AV, Gr?tzmann R, Pilarsky C. Hypermutation In Pancreatic Cancer. Gastroenterology. 2017 01; 152(1):68-74.e2.
PMID:
27856273
.
Citations:
83
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Cloyd JM,
Katz MH
, Prakash L,
Varadhachary GR
,
Wolff RA
,
Shroff RT
,
Javle M
,
Fogelman D
,
Overman M
, Crane CH,
Koay EJ
,
Das P
,
Krishnan S
,
Minsky BD
, Lee JH,
Bhutani MS
,
Weston B
, Ross W, Bhosale P,
Tamm EP
, Wang H,
Maitra A
,
Kim MP
,
Aloia TA
, Vauthey JN,
Fleming JB
, Abbruzzese JL, Pisters PW, Evans DB, Lee JE. Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience. J Gastrointest Surg. 2017 01; 21(1):164-174.
PMID:
27778257
.
Citations:
38
Fields:
Gas
Gastroenterology
Gen
General Surgery
Translation:
Humans
Bailey P, Chang DK, Lucas FA, Alvarez HA,
Haymaker C
,
Chattopadhyay C
, Kim SH,
Ekmekcioglu S
,
Grimm EA
, Biankin AV,
Hwu P
,
Maitra A
, Roszik J, Forget MA. Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma. Sci Rep. 2016 10 20; 6:35848.
PMID:
27762323
; PMCID:
PMC5071896
.
Citations:
64
Fields:
Sci
Science
Translation:
Humans
Cells
Chari ST,
Maitra A
, Srivastava S, Cleeter DF, Go VL, Rothschild LJ, Goldberg AE, Kenner BJ. Early Detection of Pancreatic Cancer-a Defined Future Using Lessons From Other Cancers: A White Paper. Pancreas. 2016 09; 45(8):1073-9.
PMID:
27518362
; PMCID:
PMC4993121
.
Citations:
19
Fields:
Gas
Gastroenterology
Translation:
Humans
Rajeshkumar NV, Yabuuchi S, Pai SG, Tong Z, Hou S, Bateman S, Pierce DW, Heise C, Von Hoff DD,
Maitra A
, Hidalgo M. Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer. Br J Cancer. 2016 08 09; 115(4):442-53.
PMID:
27441498
; PMCID:
PMC4985357
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Heeg S, Das KK, Reichert M, Bakir B, Takano S, Caspers J, Aiello NM, Wu K, Neesse A,
Maitra A
, Iacobuzio-Donahue CA, Hicks P, Rustgi AK. ETS-Transcription Factor ETV1 Regulates Stromal Expansion and?Metastasis in Pancreatic Cancer. Gastroenterology. 2016 09; 151(3):540-553.e14.
PMID:
27318148
; PMCID:
PMC5002361
.
Citations:
24
Fields:
Gas
Gastroenterology
Translation:
Animals
Cells
Carugo A,
Genovese G
, Seth S,
Nezi L
, Rose JL, Bossi D, Cicalese A, Shah PK,
Viale A
, Pettazzoni PF, Akdemir KC, Bristow CA, Robinson FS, Tepper J, Sanchez N,
Gupta S
,
Estecio MR
, Giuliani V, Dellino GI, Riva L, Yao W, Di Francesco ME, Green T, D'Alesio C, Corti D,
Kang Y
, Jones P, Wang H,
Fleming JB
,
Maitra A
, Pelicci PG, Chin L,
DePinho RA
, Lanfrancone L, Heffernan TP,
Draetta GF
. In?Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer. Cell Rep. 2016 06 28; 16(1):133-147.
PMID:
27320920
.
Citations:
55
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Omura N, Mizuma M, MacGregor A, Hong SM, Ayars M, Almario JA, Borges M, Kanda M, Li A, Vincent A,
Maitra A
, Goggins M. Overexpression of ankyrin1 promotes pancreatic cancer cell growth. Oncotarget. 2016 Jun 07; 7(23):34977-87.
PMID:
27144336
; PMCID:
PMC5085203
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Cloyd JM, Crane CH,
Koay EJ
,
Das P
,
Krishnan S
, Prakash L, Snyder RA,
Varadhachary GR
,
Wolff RA
,
Javle M
,
Shroff RT
,
Fogelman D
,
Overman M
, Wang H,
Maitra A
, Lee JE,
Fleming JB
,
Katz MH
. Impact of hypofractionated and standard fractionated chemoradiation before pancreatoduodenectomy for pancreatic ductal adenocarcinoma. Cancer. 2016 09 01; 122(17):2671-9.
PMID:
27243381
; PMCID:
PMC4992463
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Khorana AA, Mangu PB, Berlin J, Engebretson A, Hong TS,
Maitra A
, Mohile SG, Mumber M, Schulick R, Shapiro M, Urba S, Zeh HJ,
Katz MH
. Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol. 2016 07 20; 34(21):2541-56.
PMID:
27247221
.
Citations:
103
Fields:
Neo
Neoplasms
Translation:
Humans
Bernard V,
Fleming J
,
Maitra A
. Molecular and Genetic Basis of Pancreatic Carcinogenesis: Which Concepts May be Clinically Relevant? Surg Oncol Clin N Am. 2016 Apr; 25(2):227-38.
PMID:
27013361
.
Citations:
2
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Cells
Hendley AM, Wang YJ, Polireddy K, Alsina J, Ahmed I, Lafaro KJ, Zhang H, Roy N, Savidge SG, Cao Y, Hebrok M,
Maitra A
, Reynolds AB, Goggins M, Younes M, Iacobuzio-Donahue CA, Leach SD, Bailey JM. p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia. Cancer Res. 2016 06 01; 76(11):3351-63.
PMID:
27032419
; PMCID:
PMC4891257
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Wang OH, Azizian N, Guo M, Capello M, Deng D, Zang F, Fry J,
Katz MH
,
Fleming JB
, Lee JE,
Wolff RA
,
Hanash S
, Wang H,
Maitra A
. Prognostic and Functional Significance of MAP4K5 in Pancreatic Cancer. PLoS One. 2016; 11(3):e0152300.
PMID:
27023625
; PMCID:
PMC4811546
.
Citations:
13
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Drosos Y, Neale G, Ye J, Paul L, Kuliyev E,
Maitra A
, Means AL, Washington MK, Rehg J, Finkelstein DB, Sosa-Pineda B. Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation. Neoplasia. 2016 Mar; 18(3):172-84.
PMID:
26992918
; PMCID:
PMC4796801
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Zhao H, Yang L, Baddour J, Achreja A, Bernard V, Moss T,
Marini JC
, Tudawe T, Seviour EG, San Lucas FA, Alvarez H,
Gupta S
, Maiti SN, Cooper L, Peehl D,
Ram PT
,
Maitra A
, Nagrath D. Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism. Elife. 2016 Feb 27; 5:e10250.
PMID:
26920219
; PMCID:
PMC4841778
.
Citations:
356
Fields:
Bio
Biology
Translation:
Cells
Gupta S
,
Maitra A
. EMT: Matter of Life or Death? Cell. 2016 Feb 25; 164(5):840-2.
PMID:
26919422
.
Citations:
21
Fields:
Cel
Cell Biology
Translation:
Animals
Bailey P, Chang DK, Nones K, Johns AL, Patch AM,
Gingras MC
, Miller DK, Christ AN, Bruxner TJ, Quinn MC, Nourse C, Murtaugh LC, Harliwong I, Idrisoglu S, Manning S, Nourbakhsh E, Wani S, Fink L, Holmes O, Chin V, Anderson MJ, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Xu Q, Wilson PJ, Cloonan N, Kassahn KS, Taylor D, Quek K, Robertson A, Pantano L, Mincarelli L, Sanchez LN, Evers L, Wu J, Pinese M, Cowley MJ, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chantrill LA, Mawson A, Humphris J, Chou A, Pajic M, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Lovell JA, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Moran-Jones K, Jamieson NB, Graham JS, Duthie F, Oien K, Hair J,
Maitra A
, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Rusev B, Capelli P, Salvia R, Tortora G, Mukhopadhyay D, Petersen GM, Australian Pancreatic Cancer Genome Initiative, Munzy DM, Fisher WE, Karim SA, Eshleman JR, Hruban RH, Pilarsky C, Morton JP, Sansom OJ, Scarpa A, Musgrove EA, Bailey UM, Hofmann O, Sutherland RL, Wheeler DA, Gill AJ,
Gibbs RA
, Pearson JV, Waddell N, Biankin AV, Grimmond SM, Gr?tzmann R. Genomic analyses identify molecular subtypes of pancreatic cancer. Nature. 2016 Mar 03; 531(7592):47-52.
PMID:
26909576
.
Citations:
1167
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Ying H
, Dey P, Yao W, Kimmelman AC,
Draetta GF
,
Maitra A
,
DePinho RA
. Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev. 2016 Feb 15; 30(4):355-85.
PMID:
26883357
; PMCID:
PMC4762423
.
Citations:
208
Fields:
Mol
Molecular Biology
Translation:
Humans
Cells
Javle M
, Golan T,
Maitra A
. Changing the course of pancreatic cancer--Focus on recent translational advances. Cancer Treat Rev. 2016 Mar; 44:17-25.
PMID:
26924195
.
Citations:
13
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Cells
Takano S, Reichert M, Bakir B, Das KK, Nishida T, Miyazaki M, Heeg S, Collins MA, Hicks PD,
Maitra A
, Rustgi AK, Marchand B. Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization. Genes Dev. 2016 Jan 15; 30(2):233-47.
PMID:
26773005
; PMCID:
PMC4719312
.
Citations:
49
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Winnard PT, Bharti SK, Penet MF, Marik R, Mironchik Y, Wildes F,
Maitra A
, Bhujwalla ZM. Detection of Pancreatic Cancer-Induced Cachexia Using a Fluorescent Myoblast Reporter System and Analysis of Metabolite Abundance. Cancer Res. 2016 Mar 15; 76(6):1441-50.
PMID:
26719527
; PMCID:
PMC4794402
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Hayes TK, Neel NF, Hu C, Gautam P, Chenard M, Long B, Aziz M, Kassner M, Bryant KL, Pierobon M, Marayati R, Kher S, George SD, Xu M, Wang-Gillam A, Samatar AA,
Maitra A
, Wennerberg K, Petricoin EF, Yin HH, Nelkin B, Cox AD, Yeh JJ, Der CJ. Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression. Cancer Cell. 2016 Jan 11; 29(1):75-89.
PMID:
26725216
; PMCID:
PMC4816652
.
Citations:
107
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Wu PH, Phillip JM, Khatau SB, Chen WC, Stirman J, Rosseel S, Tschudi K, Van Patten J, Wong M,
Gupta S
, Baras AS, Leek JT,
Maitra A
, Wirtz D. Evolution of cellular morpho-phenotypes in cancer metastasis. Sci Rep. 2015 Dec 17; 5:18437.
PMID:
26675084
; PMCID:
PMC4682070
.
Citations:
28
Fields:
Sci
Science
Translation:
Humans
Cells
Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A,
Sharma P
, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM,
Maitra A
,
Allison JP
,
LeBleu VS
,
Kalluri R
, ?zdemir BC. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833.
PMID:
28843279
.
Citations:
74
Fields:
Neo
Neoplasms
Maitra A
. 2015 American Pancreatic Association Presidential Address: Building Relationships, Impacting Lives. Pancreas. 2015 Nov; 44(8):1167-8.
PMID:
26465942
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Cowan RW,
Maitra A
,
Rhim AD
. A New Scalpel for the Treatment of Pancreatic Cancer: Targeting Stromal-Derived STAT3 Signaling. Gastroenterology. 2015 Dec; 149(7):1685-8.
PMID:
26526714
; PMCID:
PMC5161089
.
Citations:
1
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Hu B, Sun D, Sun C, Sun YF, Sun HX, Zhu QF, Yang XR, Gao YB, Tang WG, Fan J,
Maitra A
, Anders RA, Xu Y. A polymeric nanoparticle formulation of curcumin in combination with sorafenib synergistically inhibits tumor growth and metastasis in an orthotopic model of human hepatocellular carcinoma. Biochem Biophys Res Commun. 2015 Dec 25; 468(4):525-32.
PMID:
26482853
.
Citations:
15
Fields:
Bio
Biochemistry
Bio
Biophysics
Translation:
Animals
Cells
Biankin AV,
Maitra A
. Subtyping Pancreatic Cancer. Cancer Cell. 2015 Oct 12; 28(4):411-413.
PMID:
26461089
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Katz MH
, Lee SM, Fischer LK, Prakash L, Parker N, Wang H,
Varadhachary GR
,
Wolff RA
,
Lee JE
, Pisters PW,
Maitra A
,
Fleming JB
,
Estrella J
,
Rashid A
,
Wang H
, Liu L. Superior Mesenteric Artery Margin of Posttherapy Pancreaticoduodenectomy and Prognosis in Patients With Pancreatic Ductal Adenocarcinoma. Am J Surg Pathol. 2015 Oct; 39(10):1395-403.
PMID:
26200098
.
Citations:
19
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Wang H,
Maitra A
, Wang H. The emerging roles of F-box proteins in pancreatic tumorigenesis. Semin Cancer Biol. 2016 Feb; 36:88-94.
PMID:
26384530
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Foley K, Rucki AA, Xiao Q, Zhou D, Leubner A, Mo G, Kleponis J, Wu AA, Sharma R, Jiang Q, Anders RA, Iacobuzio-Donahue CA, Hajjar KA,
Maitra A
, Jaffee EM, Zheng L. Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer. Sci Signal. 2015 Aug 04; 8(388):ra77.
PMID:
26243191
; PMCID:
PMC4811025
.
Citations:
46
Fields:
Cel
Cell Biology
Phy
Physiology
Sci
Science
Translation:
Humans
Animals
Cells
Cai J,
Maitra A
, Anders RA, Pan D, Taketo MM. ?-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis. Genes Dev. 2015 Jul 15; 29(14):1493-506.
PMID:
26193883
; PMCID:
PMC4526734
.
Citations:
92
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Sausen M, Phallen J, Adleff V, Leary RJ, Barrett MT, Anagnostou V, Parpart-Li S, Murphy D, Kay Li Q, Hruban CA, Scharpf R, White JR, O'Dwyer PJ, Allen PJ, Eshleman JR, Thompson CB, Klimstra DS, Linehan DC,
Maitra A
, Hruban RH, Diaz LA, Von Hoff DD, Johansen JS, Drebin JA, Velculescu VE, Jones S. Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients. Nat Commun. 2015 Jul 07; 6:7686.
PMID:
26154128
; PMCID:
PMC4634573
.
Citations:
182
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Hendley AM,
Maitra A
, Bailey JM. New insights into plasticity of pancreatic cancer: cancer to acinar cell reprogramming by the basic helix-loop-helix transcription factor E47. Pancreas. 2015 Jul; 44(5):683-5.
PMID:
26061556
.
Citations:
1
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Kelly K, Hollingsworth MA, Thayer SP, Ahlquist DA, Andersen DK, Batra SK, Brentnall TA, Canto M, Cleeter DF, Firpo MA, Gambhir SS, Go VL, Hines OJ, Kenner BJ, Klimstra DS, Lerch MM, Levy MJ,
Maitra A
, Mulvihill SJ, Petersen GM,
Rhim AD
, Simeone DM, Srivastava S, Tanaka M, Vinik AI, Wong D, Chari ST. Early detection of sporadic pancreatic cancer: summative review. Pancreas. 2015 Jul; 44(5):693-712.
PMID:
25931254
; PMCID:
PMC4467589
.
Citations:
97
Fields:
Gas
Gastroenterology
Translation:
Humans
Rajeshkumar NV, Dutta P, Yabuuchi S, de Wilde RF, Martinez GV, Le A, Kamphorst JJ, Rabinowitz JD, Jain SK, Hidalgo M, Dang CV, Gillies RJ,
Maitra A
. Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function. Cancer Res. 2015 Aug 15; 75(16):3355-64.
PMID:
26113084
; PMCID:
PMC4537812
.
Citations:
68
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Fischer LK,
Katz MH
, Lee SM, Liu L, Wang H,
Varadhachary GR
,
Wolff RA
, Lee JE,
Maitra A
,
Roland CL
,
Fleming JB
,
Estrella J
,
Rashid A
, Wang H. The number and ratio of positive lymph nodes affect pancreatic cancer patient survival after neoadjuvant therapy and pancreaticoduodenectomy. Histopathology. 2016 Jan; 68(2):210-20.
PMID:
25945396
; PMCID:
PMC4636488
.
Citations:
17
Fields:
Pat
Pathology
Translation:
Humans
Taniguchi C
,
Maitra A
. It's a SMAD/SMAD World. Cell. 2015 Jun 04; 161(6):1245-6.
PMID:
26046433
.
Citations:
5
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Bhutani M
, Koduru P, Lanke G, Bruno M,
Maitra A
, Giovannini M. The emerging role of endoscopic ultrasound-guided core biopsy for the evaluation of solid pancreatic masses. Minerva Gastroenterol Dietol. 2015 Jun; 61(2):51-9.
PMID:
25675155
.
Citations:
5
Fields:
Gas
Gastroenterology
Nut
Nutritional Sciences
Translation:
Humans
Capello M, Lee M, Wang H, Babel I,
Katz MH
,
Fleming JB
,
Maitra A
,
Wang H
, Tian W,
Taguchi A
,
Hanash SM
. Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma. J Natl Cancer Inst. 2015 Aug; 107(8).
PMID:
26025324
; PMCID:
PMC4554193
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Wang H,
Maitra A
,
Wang H
. Obesity, Intrapancreatic Fatty Infiltration, and Pancreatic Cancer. Clin Cancer Res. 2015 Aug 01; 21(15):3369-71.
PMID:
25995340
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Schueneman A, Goggins M, Ensor J, Saka B, Neishaboori N, Lee S,
Maitra A
,
Varadhachary G
, Rezaee N, Wolfgang C, Adsay V,
Wang H
,
Overman MJ
. Validation of histomolecular classification utilizing histological subtype, MUC1, and CDX2 for prognostication of resected ampullary adenocarcinoma. Br J Cancer. 2015 Jun 30; 113(1):64-8.
PMID:
25989273
; PMCID:
PMC4647538
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Hu C, Dadon T, Chenna V, Yabuuchi S, Bannerji R, Booher R, Strack P, Azad N, Nelkin BD,
Maitra A
. Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models. Mol Cancer Ther. 2015 Jul; 14(7):1532-9.
PMID:
25931518
; PMCID:
PMC4497872
.
Citations:
33
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Waddell N, Pajic M, Patch AM, Chang DK, Kassahn KS, Bailey P, Johns AL, Miller D, Nones K, Quek K, Quinn MC, Robertson AJ, Fadlullah MZ, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Wani S, Wilson PJ, Markham E, Cloonan N, Anderson MJ, Fink JL, Holmes O, Kazakoff SH, Leonard C, Newell F, Poudel B, Song S, Taylor D, Waddell N, Wood S, Xu Q, Wu J, Pinese M, Cowley MJ, Lee HC, Jones MD, Nagrial AM, Humphris J, Chantrill LA, Chin V, Steinmann AM, Mawson A, Humphrey ES, Colvin EK, Chou A, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Pettitt JA, Merrett ND, Toon C, Epari K, Nguyen NQ, Barbour A, Zeps N, Jamieson NB, Graham JS, Bjerkvig R, Aust D, Hruban RH,
Maitra A
, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Falconi M, Zamboni G, Tortora G, Tempero MA, Australian Pancreatic Cancer Genome Initiative, Gill AJ, Eshleman JR, Pilarsky C, Scarpa A, Musgrove EA, Pearson JV, Biankin AV, Grimmond SM, Niclou SP, Gr?tzmann R. Whole genomes redefine the mutational landscape of pancreatic cancer. Nature. 2015 Feb 26; 518(7540):495-501.
PMID:
25719666
; PMCID:
PMC4523082
.
Citations:
1014
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Hexige S, Ardito-Abraham CM, Wu Y, Wei Y, Fang Y, Han X, Li J, Zhou P, Yi Q,
Maitra A
, Liu JO, Tuveson DA, Lou W, Yu L. Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma. J Pathol. 2015 Jun; 236(2):142-154.
PMID:
25561062
; PMCID:
PMC5089710
.
Citations:
12
Fields:
Pat
Pathology
Translation:
Humans
Dal Molin M, Zhang M, de Wilde RF, Ottenhof NA, Rezaee N, Wolfgang CL, Blackford A, Vogelstein B, Kinzler KW, Papadopoulos N, Hruban RH,
Maitra A
, Wood LD. Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis. Clin Cancer Res. 2015 Apr 15; 21(8):1944-50.
PMID:
25623214
; PMCID:
PMC4401626
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC,
Maitra A
, Reynolds AB, Leach SD. p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 01; 399(1):41-53.
PMID:
25523391
; PMCID:
PMC4868343
.
Citations:
12
Fields:
Bio
Biology
Emb
Embryology
Translation:
Animals
Cells
Fishel ML, Wu X, Devlin CM, Logsdon DP, Jiang Y, Luo M, He Y, Yu Z, Tong Y, Lipking KP,
Maitra A
, Rajeshkumar NV, Scandura G, Kelley MR, Ivan M. Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2. J Biol Chem. 2015 Jan 30; 290(5):3057-68.
PMID:
25492865
; PMCID:
PMC4317024
.
Citations:
34
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Koay EJ
, Baio FE, Ondari A, Truty MJ, Cristini V, Thomas RM,
Chen R
, Chatterjee D,
Kang Y
, Zhang J,
Court L
,
Bhosale PR
,
Tamm EP
,
Qayyum A
, Crane CH,
Javle M
,
Katz MH
,
Gottumukkala VN
, Rozner MA, Shen H,
Lee JE
,
Wang H
, Chen Y, Plunkett W, Abbruzzese JL,
Wolff RA
,
Maitra A
, Ferrari M,
Varadhachary GR
,
Fleming JB
. Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer. Phys Biol. 2014 Nov 26; 11(6):065002.
PMID:
25427073
; PMCID:
PMC4266401
.
Citations:
20
Fields:
Bio
Biology
Bio
Biophysics
Translation:
Humans
Penet MF, Shah T, Bharti S, Krishnamachary B, Artemov D, Mironchik Y,
Maitra A
, Bhujwalla ZM, Wildes F. Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism. Clin Cancer Res. 2015 Jan 15; 21(2):386-95.
PMID:
25370468
; PMCID:
PMC4297549
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Chen R
, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM,
Maitra A
, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Lab Invest. 2015 Jan; 95(1):43-55.
PMID:
25347153
; PMCID:
PMC4281293
.
Citations:
29
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Cells
Devaraj S
,
Maitra A
. Pancreatic safety of newer incretin-based therapies: are the "-tides" finally turning? Diabetes. 2014 Jul; 63(7):2219-21.
PMID:
24962922
.
Citations:
5
Fields:
End
Endocrinology
Translation:
Humans
Animals
Amato E, Molin MD, Mafficini A, Yu J, Malleo G, Rusev B, Fassan M, Antonello D, Sadakari Y, Castelli P, Zamboni G,
Maitra A
, Salvia R, Hruban RH, Bassi C, Capelli P, Lawlor RT, Goggins M, Scarpa A. Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas. J Pathol. 2014 Jul; 233(3):217-27.
PMID:
24604757
; PMCID:
PMC4057302
.
Citations:
118
Fields:
Pat
Pathology
Translation:
Humans
Zhong Y, Yachida S, Rajeshkumar NV, Mudgal K, Hruban RH, Poling JS, Iacobuzio-Donahue CA, Kim MS, Abel ML, Marimuthu A, Tyner JW,
Maitra A
, Pandey A. Heterogeneity of pancreatic cancer metastases in a single patient revealed by quantitative proteomics. Mol Cell Proteomics. 2014 Nov; 13(11):2803-11.
PMID:
24895378
; PMCID:
PMC4223473
.
Citations:
30
Fields:
Bio
Biochemistry
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Yang A, Rajeshkumar NV, Wang X, Yabuuchi S, Alexander BM, Chu GC, Von Hoff DD,
Maitra A
, Kimmelman AC. Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations. Cancer Discov. 2014 Aug; 4(8):905-13.
PMID:
24875860
; PMCID:
PMC4125497
.
Citations:
226
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Kim MS, Pinto SM, Getnet D, Nirujogi RS, Manda SS, Chaerkady R, Madugundu AK, Kelkar DS, Isserlin R, Jain S, Thomas JK, Muthusamy B, Leal-Rojas P, Kumar P, Sahasrabuddhe NA, Balakrishnan L, Advani J, George B, Renuse S, Selvan LD, Patil AH, Nanjappa V, Radhakrishnan A, Prasad S, Subbannayya T, Raju R, Kumar M, Sreenivasamurthy SK, Marimuthu A, Sathe GJ, Chavan S, Datta KK, Subbannayya Y, Sahu A, Yelamanchi SD, Jayaram S, Rajagopalan P, Sharma J, Murthy KR, Syed N, Goel R, Khan AA, Ahmad S, Dey G, Mudgal K, Chatterjee A, Huang TC, Zhong J, Wu X, Shaw PG, Freed D, Zahari MS, Mukherjee KK, Shankar S, Mahadevan A, Lam H, Mitchell CJ, Shankar SK, Satishchandra P, Schroeder JT, Sirdeshmukh R,
Maitra A
, Leach SD, Drake CG, Halushka MK, Prasad TS, Hruban RH, Kerr CL, Bader GD, Iacobuzio-Donahue CA, Gowda H, Pandey A. A draft map of the human proteome. Nature. 2014 May 29; 509(7502):575-81.
PMID:
24870542
; PMCID:
PMC4403737
.
Citations:
856
Fields:
Sci
Science
Translation:
Humans
Cells
Chivukula RR, Shi G, Acharya A, Mills EW, Zeitels LR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC,
Maitra A
, Mendell JT. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 2014 May 22; 157(5):1104-16.
PMID:
24855947
; PMCID:
PMC4175516
.
Citations:
99
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Novitskiy SV, De Jesus-Acosta A,
Sharma P
, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM,
Allison JP
, ?zdemir BC, Sugimoto H, Kahlert C,
Maitra A
,
LeBleu VS
,
Kalluri R
. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34.
PMID:
24856586
; PMCID:
PMC4180632
.
Citations:
944
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Thomas JK, Kim MS, Balakrishnan L, Nanjappa V, Raju R, Marimuthu A, Radhakrishnan A, Khan AA, Sakamuri S, Tankala SG, Singal M, Nair B, Sirdeshmukh R, Chatterjee A, Prasad TS,
Maitra A
, Gowda H, Hruban RH, Pandey A, Muthusamy B. Pancreatic Cancer Database: an integrative resource for pancreatic cancer. Cancer Biol Ther. 2014 Aug; 15(8):963-7.
PMID:
24839966
; PMCID:
PMC4119079
.
Citations:
28
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Vincent A, Hong SM, Hu C, Omura N, Young A, Kim H, Yu J, Knight S, Ayars M, Griffith M, Van Seuningen I,
Maitra A
, Goggins M. Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth. Oncotarget. 2014 May 15; 5(9):2575-87.
PMID:
24810906
; PMCID:
PMC4058028
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
McAllister F
, Bailey JM, Alsina J, Nirschl CJ, Sharma R, Fan H, Rattigan Y, Roeser JC, Lankapalli RH, Zhang H, Jaffee EM, Drake CG, Housseau F,
Maitra A
, Kolls JK, Sears CL, Pardoll DM, Leach SD. Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia. Cancer Cell. 2014 May 12; 25(5):621-37.
PMID:
24823639
; PMCID:
PMC4072043
.
Citations:
171
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Das S, Bedja D, Campbell N, Dunkerly B, Chenna V,
Maitra A
, Steenbergen C. miR-181c regulates the mitochondrial genome, bioenergetics, and propensity for heart failure in vivo. PLoS One. 2014; 9(5):e96820.
PMID:
24810628
; PMCID:
PMC4014556
.
Citations:
73
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
De Jesus-Acosta A, Laheru D,
Maitra A
, Arcaroli J, Rudek MA,
Dasari A
, Blatchford PJ, Quackenbush K, Messersmith W. A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma. Invest New Drugs. 2014 Aug; 32(4):739-45.
PMID:
24668033
; PMCID:
PMC4292847
.
Citations:
48
Fields:
Ant
Antineoplastic Agents
Pha
Pharmacology
Translation:
Humans
CT
Clinical Trials
Pekala KR, Ma X, Kropp PA, Petersen CP, Hudgens CW, Chung CH, Shi C, Merchant NB,
Maitra A
, Means AL, Gannon MA. Loss of HNF6 expression correlates with human pancreatic cancer progression. Lab Invest. 2014 May; 94(5):517-27.
PMID:
24638272
; PMCID:
PMC4068339
.
Citations:
11
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Animals
Cells
Keenan BP, Saenger Y, Kafrouni MI, Leubner A, Lauer P,
Maitra A
, Rucki AA, Gunderson AJ, Coussens LM, Brockstedt DG, Dubensky TW, Hassan R, Armstrong TD, Jaffee EM. A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice. Gastroenterology. 2014 Jun; 146(7):1784-94.e6.
PMID:
24607504
; PMCID:
PMC4035450
.
Citations:
62
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Rodic N, Sharma R, Sharma R, Zampella J, Dai L, Taylor MS, Hruban RH, Iacobuzio-Donahue CA,
Maitra A
, Torbenson MS, Goggins M, Shih IeM, Duffield AS, Montgomery EA, Gabrielson E, Netto GJ, Lotan TL, De Marzo AM, Westra W, Binder ZA, Orr BA, Gallia GL, Eberhart CG, Boeke JD, Harris CR, Burns KH. Long interspersed element-1 protein expression is a hallmark of many human cancers. Am J Pathol. 2014 May; 184(5):1280-6.
PMID:
24607009
; PMCID:
PMC4005969
.
Citations:
112
Fields:
Pat
Pathology
Translation:
Humans
Cells
Jiao Y, Yonescu R, Offerhaus GJ, Klimstra DS,
Maitra A
, Eshleman JR, Herman JG, Poh W, Pelosof L, Wolfgang CL, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N, Wood LD. Whole-exome sequencing of pancreatic neoplasms with acinar differentiation. J Pathol. 2014 Mar; 232(4):428-35.
PMID:
24293293
; PMCID:
PMC4048021
.
Citations:
71
Fields:
Pat
Pathology
Translation:
Humans
Cells
Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Wolfgang CL, Kinzler KW, Vogelstein B,
Maitra A
, Hruban RH, Matthaei H, Kalff JC. GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs". Am J Surg Pathol. 2014 Mar; 38(3):360-3.
PMID:
24525507
; PMCID:
PMC3927228
.
Citations:
20
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Streppel MM, Montgomery EA,
Maitra A
. New advances in the pathogenesis and progression of barrett's esophagus. Curr Mol Med. 2014 Jan; 14(1):58-68.
PMID:
23865431
.
Citations:
3
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Cowan RW,
Maitra A
. Genetic progression of pancreatic cancer. Cancer J. 2014 Jan-Feb; 20(1):80-4.
PMID:
24445769
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Shrivastava MS, Hussain Z, Giricz O, Shenoy N, Polineni R,
Maitra A
, Verma A. Targeting chemokine pathways in esophageal adenocarcinoma. Cell Cycle. 2014; 13(21):3320-7.
PMID:
25485576
; PMCID:
PMC4614313
.
Citations:
15
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Nimmagadda S, Pullambhatla M, Lisok A, Hu C,
Maitra A
, Pomper MG. Imaging Axl expression in pancreatic and prostate cancer xenografts. Biochem Biophys Res Commun. 2014 Jan 10; 443(2):635-40.
PMID:
24333418
; PMCID:
PMC3918901
.
Citations:
8
Fields:
Bio
Biochemistry
Bio
Biophysics
Translation:
Animals
Cells
Canto MI,
Anandasabapathy S
, Brugge W, Falk GW, Dunbar KB, Zhang Z, Woods K, Almario JA, Schell U, Goldblum J,
Maitra A
, Montgomery E, Kiesslich R, Confocal Endomicroscopy for Barrett's Esophagus or Confocal Endomicroscopy for Barrett's Esophagus (. In vivo endomicroscopy improves detection of Barrett's esophagus-related neoplasia: a multicenter international randomized controlled trial (with video). Gastrointest Endosc. 2014 Feb; 79(2):211-21.
PMID:
24219822
; PMCID:
PMC4668117
.
Citations:
68
Fields:
Dia
Diagnostic Imaging
Gas
Gastroenterology
The
Therapeutics
Translation:
Humans
Jiao Y, Pawlik TM, Anders RA, Selaru FM, Streppel MM, Lucas DJ, Niknafs N, Guthrie VB,
Maitra A
, Argani P, Offerhaus GJA, Roa JC, Roberts LR, Gores GJ, Popescu I, Alexandrescu ST, Dima S, Fassan M, Simbolo M, Mafficini A, Capelli P, Lawlor RT, Ruzzenente A, Guglielmi A, Tortora G, de Braud F, Scarpa A, Jarnagin W, Klimstra D, Karchin R, Velculescu VE, Hruban RH, Vogelstein B, Kinzler KW, Papadopoulos N, Wood LD. Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas. Nat Genet. 2013 Dec; 45(12):1470-1473.
PMID:
24185509
; PMCID:
PMC4013720
.
Citations:
280
Fields:
Gen
Genetics
Translation:
Humans
Liddle RA, Freeman M, Simeone DM, Saluja AK, Castillo CF,
Maitra A
, Pandol SJ, Go VL. Minutes of the business meeting of the American Pancreatic Association, Friday, November 2, 2012, Miami, Florida. Pancreas. 2013 Nov; 42(8):1333-4.
PMID:
24152959
; PMCID:
PMC4912134
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Bailey JM, Alsina J, Rasheed ZA, McAllister FM, Fu YY, Plentz R, Zhang H, Pasricha PJ, Bardeesy N, Matsui W,
Maitra A
, Leach SD. DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer. Gastroenterology. 2014 Jan; 146(1):245-56.
PMID:
24096005
; PMCID:
PMC3910427
.
Citations:
156
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
He P, Tan H, Budhu A, Gaedcke J, Ghadimi BM, Ried T, Yfantis HG, Lee DH,
Maitra A
, Hanna N, Alexander HR, Hussain SP, Zhang G. Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer. Clin Cancer Res. 2013 Sep 15; 19(18):4983-93.
PMID:
23918603
; PMCID:
PMC3778077
.
Citations:
129
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L,
Maitra A
, Greally JM, Verma A. Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. Nucleic Acids Res. 2013 Sep; 41(16):e157.
PMID:
23861445
; PMCID:
PMC3763560
.
Citations:
31
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Molin MD, Matthaei H, Wu J, Blackford A, Debeljak M, Rezaee N, Wolfgang CL, Butturini G, Salvia R, Bassi C, Goggins MG, Kinzler KW, Vogelstein B, Eshleman JR, Hruban RH,
Maitra A
. Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas. Ann Surg Oncol. 2013 Nov; 20(12):3802-8.
PMID:
23846778
; PMCID:
PMC3842009
.
Citations:
57
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Streppel MM, Pai S, Campbell NR, Hu C, Yabuuchi S, Canto MI, Wang JS, Montgomery EA,
Maitra A
. MicroRNA 223 is upregulated in the multistep progression of Barrett's esophagus and modulates sensitivity to chemotherapy by targeting PARP1. Clin Cancer Res. 2013 Aug 01; 19(15):4067-78.
PMID:
23757351
; PMCID:
PMC3745277
.
Citations:
36
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Wild AT, Gandhi N, Chettiar ST, Aziz K, Gajula RP, Williams RD, Kumar R, Taparra K, Zeng J, Cades JA, Velarde E, Menon S, Geschwind JF, Cosgrove D, Pawlik TM,
Maitra A
, Wong J, Hales RK, Torbenson MS, Herman JM, Tran PT. Concurrent versus sequential sorafenib therapy in combination with radiation for hepatocellular carcinoma. PLoS One. 2013; 8(6):e65726.
PMID:
23762417
; PMCID:
PMC3675179
.
Citations:
18
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Zou P, Helson L,
Maitra A
, Stern ST, McNeil SE. Polymeric curcumin nanoparticle pharmacokinetics and metabolism in bile duct cannulated rats. Mol Pharm. 2013 May 06; 10(5):1977-87.
PMID:
23534919
; PMCID:
PMC3683459
.
Citations:
12
Fields:
Mol
Molecular Biology
Pha
Pharmacology
Translation:
Animals
Yegnasubramanian S,
Maitra A
. Aiming for the outliers: cancer precision medicine through targeting kinases with extreme expression. Cancer Discov. 2013 Mar; 3(3):252-4.
PMID:
23475875
; PMCID:
PMC4486056
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Funamizu N, Hu C, Lacy C, Schetter A, Zhang G, He P, Gaedcke J, Ghadimi MB, Ried T, Yfantis HG, Lee DH, Subleski J, Chan T, Weiss JM, Back TC, Yanaga K, Hanna N, Alexander HR,
Maitra A
, Hussain SP. Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. Int J Cancer. 2013 Feb 15; 132(4):785-94.
PMID:
22821831
; PMCID:
PMC3488363
.
Citations:
55
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Yabuuchi S, Pai SG, Campbell NR, de Wilde RF, De Oliveira E, Korangath P, Streppel MM, Rasheed ZA, Hidalgo M,
Maitra A
, Rajeshkumar NV. Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer. Cancer Lett. 2013 Jul 10; 335(1):41-51.
PMID:
23402814
; PMCID:
PMC3665739
.
Citations:
73
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Zheng G, Martignoni G, Antonescu C, Montgomery E, Eberhart C, Netto G, Taube J, Westra W, Epstein JI, Lotan T,
Maitra A
, Gabrielson E, Torbenson M, Iacobuzio-Donahue C, Demarzo A, Shih IeM, Illei P, Wu TC, Argani P. A broad survey of cathepsin K immunoreactivity in human neoplasms. Am J Clin Pathol. 2013 Feb; 139(2):151-9.
PMID:
23355199
; PMCID:
PMC3957187
.
Citations:
10
Fields:
Pat
Pathology
Translation:
Humans
Khalaileh A, Dreazen A, Khatib A, Apel R, Swisa A, Kidess-Bassir N,
Maitra A
, Meyuhas O, Dor Y, Zamir G. Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer. Cancer Res. 2013 Mar 15; 73(6):1811-20.
PMID:
23361300
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Kamiyama H, Rauenzahn S, Shim JS, Karikari CA, Feldmann G, Hua L, Kamiyama M, Schuler FW, Lin MT, Beaty RM, Karanam B, Liang H, Mullendore ME, Mo G, Hidalgo M, Jaffee E, Hruban RH, Jinnah HA, Roden RB, Jimeno A, Liu JO,
Maitra A
, Eshleman JR. Personalized chemotherapy profiling using cancer cell lines from selectable mice. Clin Cancer Res. 2013 Mar 01; 19(5):1139-46.
PMID:
23340293
; PMCID:
PMC3612923
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Streppel MM, Lata S, DelaBastide M, Montgomery EA, Wang JS, Canto MI, Macgregor-Das AM, Pai S, Morsink FH, Offerhaus GJ, Antoniou E,
Maitra A
, McCombie WR. Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett's esophagus. Oncogene. 2014 Jan 16; 33(3):347-57.
PMID:
23318448
; PMCID:
PMC3805724
.
Citations:
46
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Matthaei H, Dal Molin M,
Maitra A
. Identification and analysis of precursors to invasive pancreatic cancer. Methods Mol Biol. 2013; 980:1-12.
PMID:
23359146
.
Citations:
5
Fields:
Mol
Molecular Biology
Translation:
Humans
Maitra A
, Leach SD. Disputed paternity: the uncertain ancestry of pancreatic ductal neoplasia. Cancer Cell. 2012 Dec 11; 22(6):701-3.
PMID:
23238009
; PMCID:
PMC3526877
.
Citations:
12
Fields:
Neo
Neoplasms
Venkannagari S,
Fiskus W
, Peth K, Atadja P, Hidalgo M,
Maitra A
,
Bhalla KN
. Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer. Oncotarget. 2012 Nov; 3(11):1416-27.
PMID:
23232026
; PMCID:
PMC3717802
.
Citations:
27
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
McDonald OG,
Maitra A
, Hruban RH. Human correlates of provocative questions in pancreatic pathology. Adv Anat Pathol. 2012 Nov; 19(6):351-62.
PMID:
23060061
; PMCID:
PMC3487591
.
Citations:
15
Fields:
Ana
Anatomy
Pat
Pathology
Translation:
Humans
Animals
Cells
Biankin AV, Waddell N, Kassahn KS,
Gingras MC
, Muthuswamy LB, Johns AL, Miller DK, Wilson PJ, Patch AM, Wu J, Chang DK, Cowley MJ, Gardiner BB, Song S, Harliwong I, Idrisoglu S, Nourse C, Nourbakhsh E, Manning S, Wani S, Gongora M, Pajic M, Scarlett CJ, Gill AJ, Pinho AV, Rooman I, Anderson M, Holmes O, Leonard C, Taylor D, Wood S, Xu Q, Nones K, Fink JL, Christ A, Bruxner T, Cloonan N, Kolle G, Newell F, Pinese M, Mead RS, Humphris JL, Kaplan W, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chou A, Chin VT, Chantrill LA, Mawson A, Samra JS, Kench JG, Lovell JA, Daly RJ, Merrett ND, Toon C, Epari K, Nguyen NQ, Barbour A, Zeps N, Australian Pancreatic Cancer Genome Initiative, Kakkar N, Zhao F, Wu YQ, Wang M,
Muzny DM
, Fisher WE, Brunicardi FC, Hodges SE, Reid JG, Drummond J, Chang K, Han Y, Lewis LR, Dinh H, Buhay CJ, Beck T, Timms L, Sam M, Begley K, Brown A, Pai D, Panchal A, Buchner N, De Borja R, Denroche RE, Yung CK, Serra S, Onetto N, Mukhopadhyay D, Tsao MS, Shaw PA, Petersen GM, Gallinger S, Hruban RH,
Maitra A
, Iacobuzio-Donahue CA, Schulick RD, Wolfgang CL, Morgan RA, Lawlor RT, Capelli P, Corbo V, Scardoni M, Tortora G, Tempero MA, Mann KM, Jenkins NA, Perez-Mancera PA, Adams DJ, Largaespada DA, Wessels LF, Rust AG, Stein LD, Tuveson DA, Copeland NG, Musgrove EA, Scarpa A, Eshleman JR, Hudson TJ, Sutherland RL, Wheeler DA, Pearson JV, McPherson JD,
Gibbs RA
, Grimmond SM. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature. 2012 Nov 15; 491(7424):399-405.
PMID:
23103869
; PMCID:
PMC3530898
.
Citations:
939
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Cardoso AA, Jiang Y, Luo M, Reed AM, Shahda S, He Y,
Maitra A
, Kelley MR, Fishel ML. APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival. PLoS One. 2012; 7(10):e47462.
PMID:
23094050
; PMCID:
PMC3477158
.
Citations:
46
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
O'Neal RL, Nam KT, LaFleur BJ, Barlow B, Nozaki K, Lee HJ, Kim WH, Yang HK, Shi C,
Maitra A
, Montgomery E, Washington MK, El Rifai W, Drapkin RI, Goldenring JR. Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas. Hum Pathol. 2013 May; 44(5):734-42.
PMID:
23084584
; PMCID:
PMC3556378
.
Citations:
20
Fields:
Pat
Pathology
Translation:
Humans
Cells
Kim MS, Kuppireddy SV, Sakamuri S, Singal M, Getnet D, Harsha HC, Goel R, Balakrishnan L, Jacob HK, Kashyap MK, Tankala SG,
Maitra A
, Iacobuzio-Donahue CA, Jaffee E, Goggins MG, Velculescu VE, Hruban RH, Pandey A. Rapid characterization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs). J Proteome Res. 2012 Nov 02; 11(11):5556-63.
PMID:
22985314
; PMCID:
PMC3565537
.
Citations:
6
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Penchev VR, Rasheed ZA,
Maitra A
, Matsui W. Heterogeneity and targeting of pancreatic cancer stem cells. Clin Cancer Res. 2012 Aug 15; 18(16):4277-84.
PMID:
22896694
; PMCID:
PMC3422767
.
Citations:
38
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Le A, Rajeshkumar NV,
Maitra A
, Dang CV. Conceptual framework for cutting the pancreatic cancer fuel supply. Clin Cancer Res. 2012 Aug 15; 18(16):4285-90.
PMID:
22896695
; PMCID:
PMC3545437
.
Citations:
32
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Chen R
, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, Lane Z, Post J, Bronner MP,
Maitra A
, Brentnall TA, Willmann JK. Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma. Cancer Biol Ther. 2012 Aug; 13(10):899-907.
PMID:
22785208
; PMCID:
PMC3414412
.
Citations:
32
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Chun YS, Bisht S, Chenna V, Pramanik D, Yoshida T, Hong SM, de Wilde RF, Zhang Z, Huso DL, Zhao M, Rudek MA, Stearns V,
Maitra A
, Sukumar S. Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations. Carcinogenesis. 2012 Nov; 33(11):2242-9.
PMID:
22831956
; PMCID:
PMC3584967
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Animals
Dallas MR, Chen SH, Streppel MM, Sharma S,
Maitra A
, Konstantopoulos K. Sialofucosylated podocalyxin is a functional E- and L-selectin ligand expressed by metastatic pancreatic cancer cells. Am J Physiol Cell Physiol. 2012 Sep 15; 303(6):C616-24.
PMID:
22814396
; PMCID:
PMC3468350
.
Citations:
33
Fields:
Cel
Cell Biology
Phy
Physiology
Translation:
Humans
Animals
Cells
Yamanaka S, Campbell NR, An F, Kuo SC, Potter JJ, Mezey E,
Maitra A
, Selaru FM. Coordinated effects of microRNA-494 induce G2/M arrest in human cholangiocarcinoma. Cell Cycle. 2012 Jul 15; 11(14):2729-38.
PMID:
22785131
; PMCID:
PMC3409013
.
Citations:
41
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Mizuma M, Rasheed ZA, Yabuuchi S, Omura N, Campbell NR, de Wilde RF, De Oliveira E, Zhang Q, Puig O, Matsui W, Hidalgo M,
Maitra A
, Rajeshkumar NV. The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models. Mol Cancer Ther. 2012 Sep; 11(9):1999-2009.
PMID:
22752426
; PMCID:
PMC3438318
.
Citations:
39
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Cui Y, Brosnan JA, Blackford AL, Sur S, Hruban RH, Kinzler KW, Vogelstein B,
Maitra A
, Diaz LA, Iacobuzio-Donahue CA, Eshleman JR. Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity. Clin Cancer Res. 2012 Dec 01; 18(23):6519-30.
PMID:
22753594
; PMCID:
PMC3513499
.
Citations:
29
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Matthaei H, Wylie D, Lloyd MB, Dal Molin M, Kemppainen J, Mayo SC, Wolfgang CL, Schulick RD, Langfield L, Andruss BF, Adai AT, Hruban RH, Szafranska-Schwarzbach AE,
Maitra A
. miRNA biomarkers in cyst fluid augment the diagnosis and management of pancreatic cysts. Clin Cancer Res. 2012 Sep 01; 18(17):4713-24.
PMID:
22723372
; PMCID:
PMC3547600
.
Citations:
78
Fields:
Neo
Neoplasms
Translation:
Humans
Matthaei H, Wu J, Dal Molin M, Debeljak M, Lingohr P, Katabi N, Klimstra DS, Adsay NV, Eshleman JR, Schulick RD, Kinzler KW, Vogelstein B, Hruban RH,
Maitra A
. GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct. HPB (Oxford). 2012 Oct; 14(10):677-83.
PMID:
22954004
; PMCID:
PMC3461374
.
Citations:
14
Fields:
Gas
Gastroenterology
Translation:
Humans
Pramanik D, Campbell NR, Das S,
Gupta S
, Chenna V, Bisht S, Sysa-Shah P, Bedja D, Karikari C, Steenbergen C, Gabrielson KL, Maitra A,
Maitra A
. A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy. Oncotarget. 2012 Jun; 3(6):640-50.
PMID:
22791660
; PMCID:
PMC3442295
.
Citations:
31
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Iwatate M, Matsubayashi H, Sasaki K, Kishida N, Yoshikawa S, Ono H,
Maitra A
. Functional pancreatic acinar cell carcinoma extending into the main pancreatic duct and splenic vein. J Gastrointest Cancer. 2012 Jun; 43(2):373-8.
PMID:
20703831
.
Citations:
6
Fields:
Gas
Gastroenterology
Neo
Neoplasms
Translation:
Humans
Hillion J, Smail SS, Di Cello F, Belton A, Shah SN, Huso T, Schuldenfrei A, Nelson DM, Cope L, Campbell N, Karikari C, Aderinto A,
Maitra A
, Huso DL, Resar LM. The HMGA1-COX-2 axis: a key molecular pathway and potential target in pancreatic adenocarcinoma. Pancreatology. 2012 Jul-Aug; 12(4):372-9.
PMID:
22898640
; PMCID:
PMC3466102
.
Citations:
22
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Agarwal A, Polineni R, Hussein Z, Vigoda I, Bhagat TD, Bhattacharyya S,
Maitra A
, Verma A. Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma. Int J Clin Exp Pathol. 2012; 5(5):382-96.
PMID:
22808291
; PMCID:
PMC3396065
.
Citations:
20
Fields:
Pat
Pathology
Translation:
Humans
Cells
de Wilde RF, Heaphy CM,
Maitra A
, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar IQ, Valk GD, Vriens MR, Borel Rinkes IH, Offerhaus GJ, Hruban RH, Matsukuma KE. Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. Mod Pathol. 2012 Jul; 25(7):1033-9.
PMID:
22575867
; PMCID:
PMC3547622
.
Citations:
63
Fields:
Pat
Pathology
Translation:
Humans
Cells
Rust AG, van der Weyden L, Kristiansen G, Li A, Sarver AL, Silverstein KA, Aust D, Herd C, Stemple DL, Kettleborough R, Brosnan JA, Li A, Morgan R, Knight S, Yu J, Stegeman S, Collier LS, ten Hoeve JJ, de Ridder J, Klein AP, Goggins M, Hruban RH, Chang DK, Biankin AV, Grimmond SM, Australian Pancreatic Cancer Genome Initiative, Wessels LF, Wood SA, Iacobuzio-Donahue CA, Pilarsky C, Largaespada DA, Adams DJ, Tuveson DA, P?rez-Mancera PA, Gr?tzmann R, R?mmele P, Kn?sel T. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 2012 Apr 29; 486(7402):266-70.
PMID:
22699621
; PMCID:
PMC3376394
.
Citations:
175
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Streppel MM, Vincent A, Mukherjee R, Campbell NR, Chen SH, Konstantopoulos K, Goggins MG, Van Seuningen I,
Maitra A
, Montgomery EA. Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon. Hum Pathol. 2012 Oct; 43(10):1755-63.
PMID:
22542127
; PMCID:
PMC3547617
.
Citations:
54
Fields:
Pat
Pathology
Translation:
Humans
Cells
Zhang G, Schetter A, He P, Funamizu N, Gaedcke J, Ghadimi BM, Ried T, Hassan R, Yfantis HG, Lee DH, Lacy C,
Maitra A
, Hanna N, Alexander HR, Hussain SP. DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. PLoS One. 2012; 7(2):e31507.
PMID:
22363658
; PMCID:
PMC3282755
.
Citations:
110
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
de Wilde RF, Edil BH, Hruban RH,
Maitra A
. Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy. Nat Rev Gastroenterol Hepatol. 2012 Feb 07; 9(4):199-208.
PMID:
22310917
; PMCID:
PMC3544293
.
Citations:
34
Fields:
Gas
Gastroenterology
Translation:
Humans
Leidner RS, Ravi L, Leahy P, Chen Y, Bednarchik B, Streppel M, Canto M, Wang JS,
Maitra A
, Willis J, Markowitz SD, Barnholtz-Sloan J, Adams MD, Chak A, Guda K. The microRNAs, MiR-31 and MiR-375, as candidate markers in Barrett's esophageal carcinogenesis. Genes Chromosomes Cancer. 2012 May; 51(5):473-9.
PMID:
22302717
; PMCID:
PMC3547654
.
Citations:
33
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Matthaei H, Norris AL, Tsiatis AC, Olino K, Hong SM, dal Molin M, Goggins MG, Canto M, Horton KM, Jackson KD, Capelli P, Zamboni G, Bortesi L, Furukawa T, Egawa S, Ishida M, Ottomo S, Unno M, Motoi F, Wolfgang CL, Edil BH, Cameron JL, Eshleman JR, Schulick RD,
Maitra A
, Hruban RH. Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas. Ann Surg. 2012 Feb; 255(2):326-33.
PMID:
22167000
; PMCID:
PMC3534752
.
Citations:
41
Fields:
Gen
General Surgery
Translation:
Humans
Cells
Yachida S, Vakiani E, White CM, Zhong Y, Saunders T, Morgan R, de Wilde RF,
Maitra A
, Hicks J, Demarzo AM, Shi C, Sharma R, Laheru D, Edil BH, Wolfgang CL, Schulick RD, Hruban RH, Tang LH, Klimstra DS, Iacobuzio-Donahue CA. Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors. Am J Surg Pathol. 2012 Feb; 36(2):173-84.
PMID:
22251937
; PMCID:
PMC3261427
.
Citations:
163
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Lee KH, Galloway JF, Park J, Dvoracek CM, Dallas M, Konstantopoulos K,
Maitra A
, Searson PC. Quantitative molecular profiling of biomarkers for pancreatic cancer with functionalized quantum dots. Nanomedicine. 2012 Oct; 8(7):1043-51.
PMID:
22306154
; PMCID:
PMC3354032
.
Citations:
12
Fields:
Bio
Biotechnology
Nan
Nanotechnology
Translation:
Humans
Cells
Rhim AD
, Mirek ET, Aiello NM,
Maitra A
, Bailey JM,
McAllister F
, Reichert M, Beatty GL, Rustgi AK, Vonderheide RH, Leach SD, Stanger BZ. EMT and dissemination precede pancreatic tumor formation. Cell. 2012 Jan 20; 148(1-2):349-61.
PMID:
22265420
; PMCID:
PMC3266542
.
Citations:
938
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Shain AH, Giacomini CP, Matsukuma K, Karikari CA, Bashyam MD, Hidalgo M,
Maitra A
, Pollack JR. Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):E252-9.
PMID:
22233809
; PMCID:
PMC3277150
.
Citations:
110
Fields:
Sci
Science
Translation:
Humans
Cells
Kanda M, Matthaei H, Wu J, Hong SM, Yu J, Borges M, Hruban RH,
Maitra A
, Kinzler K, Vogelstein B, Goggins M. Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia. Gastroenterology. 2012 Apr; 142(4):730-733.e9.
PMID:
22226782
; PMCID:
PMC3321090
.
Citations:
302
Fields:
Gas
Gastroenterology
Translation:
Humans
Streppel MM, Siersema PD, de Leng WW, Morsink FH, Vleggaar FP,
Maitra A
, Montgomery EA, Offerhaus GJ. Squamous cell carcinoma in Barrett's esophagus: field effect versus metastasis. Dis Esophagus. 2012 Sep-Oct; 25(7):630-7.
PMID:
22221671
; PMCID:
PMC3568520
.
Citations:
4
Fields:
Gas
Gastroenterology
Translation:
Humans
Wu J, Jiao Y, Dal Molin M,
Maitra A
, de Wilde RF, Wood LD, Eshleman JR, Goggins MG, Wolfgang CL, Canto MI, Schulick RD, Edil BH, Choti MA, Adsay V, Klimstra DS, Offerhaus GJ, Klein AP, Kopelovich L, Carter H, Karchin R, Allen PJ, Schmidt CM, Naito Y, Diaz LA, Kinzler KW, Papadopoulos N, Hruban RH, Vogelstein B. Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21188-93.
PMID:
22158988
; PMCID:
PMC3248495
.
Citations:
242
Fields:
Sci
Science
Translation:
Humans
Cells
Li M,
Parsons DW
, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M,
Maitra A
, Malek SN, Powell S, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N, Jones S. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum Mutat. 2012 Jan; 33(1):100-3.
PMID:
22009941
; PMCID:
PMC3240719
.
Citations:
138
Fields:
Gen
Genetics
Translation:
Humans
Cells
Chenna V, Hu C, Pramanik D, Aftab BT, Karikari C, Campbell NR, Hong SM, Zhao M, Rudek MA, Khan SR, Rudin CM,
Maitra A
. A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists. Mol Cancer Ther. 2012 Jan; 11(1):165-73.
PMID:
22027695
; PMCID:
PMC3256300
.
Citations:
36
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Gupta S
, Pramanik D, Mukherjee R, Campbell NR, Elumalai S, de Wilde RF, Hong SM, Goggins MG, De Jesus-Acosta A, Laheru D,
Maitra A
. Molecular determinants of retinoic acid sensitivity in pancreatic cancer. Clin Cancer Res. 2012 Jan 01; 18(1):280-9.
PMID:
22010213
; PMCID:
PMC3251696
.
Citations:
32
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Von Hoff DD, Ramanathan RK, Borad MJ, Laheru DA, Smith LS, Wood TE, Korn RL, Desai N, Trieu V, Iglesias JL, Zhang H, Soon-Shiong P, Shi T, Rajeshkumar NV,
Maitra A
, Hidalgo M. Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial. J Clin Oncol. 2011 Dec 01; 29(34):4548-54.
PMID:
21969517
; PMCID:
PMC3565012
.
Citations:
424
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
CT
Clinical Trials
Feldmann G, Mishra A, Bisht S, Karikari C, Garrido-Laguna I, Rasheed Z, Ottenhof NA, Dadon T, Alvarez H, Fendrich V, Rajeshkumar NV, Matsui W, Brossart P, Hidalgo M, Bannerji R,
Maitra A
, Nelkin BD. Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models. Cancer Biol Ther. 2011 Oct 01; 12(7):598-609.
PMID:
21768779
; PMCID:
PMC3218385
.
Citations:
58
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Fendrich V, Oh E, Bang S, Karikari C, Ottenhof N, Bisht S, Lauth M, Brossart P, Katsanis N,
Maitra A
, Feldmann G. Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas. Neoplasia. 2011 Oct; 13(10):923-30.
PMID:
22028618
; PMCID:
PMC3201569
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Zhang YA,
Maitra A
, Hsieh JT, Rudin CM, Peacock CD, Karikari C, Brekken RA, Stastny V, Gao B, Girard L,
Wistuba I
, Frenkel E, Minna JD, Gazdar AF. Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts. Cancer Biol Ther. 2011 Oct 01; 12(7):617-28.
PMID:
21750403
; PMCID:
PMC3218386
.
Citations:
20
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
PH
Public Health
Park JY, Hong SM, Klimstra DS, Goggins MG,
Maitra A
, Hruban RH. Pdx1 expression in pancreatic precursor lesions and neoplasms. Appl Immunohistochem Mol Morphol. 2011 Oct; 19(5):444-9.
PMID:
21297446
; PMCID:
PMC3123421
.
Citations:
25
Fields:
His
Histocytochemistry
Mol
Molecular Biology
Translation:
Humans
Cells
Dal Molin M, Hong SM, Hebbar S, Sharma R, Scrimieri F, de Wilde RF, Mayo SC, Goggins M, Wolfgang CL, Schulick RD, Lin MT, Eshleman JR, Hruban RH,
Maitra A
, Matthaei H. Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas. Hum Pathol. 2012 Apr; 43(4):585-91.
PMID:
21940037
; PMCID:
PMC3246530
.
Citations:
31
Fields:
Pat
Pathology
Translation:
Humans
Cells
Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih IeM, Iacobuzio-Donahue CA,
Maitra A
, Li QK, Eberhart CG, Taube JM, Rakheja D, Kurman RJ, Wu TC, Roden RB, Argani P, De Marzo AM, Terracciano L, Torbenson M, Meeker AK. Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. Am J Pathol. 2011 Oct; 179(4):1608-15.
PMID:
21888887
; PMCID:
PMC3181356
.
Citations:
225
Fields:
Pat
Pathology
Translation:
Humans
Cells
Xu Y, Chenna V, Hu C, Sun HX, Khan M, Bai H, Yang XR, Zhu QF, Sun YF,
Maitra A
, Fan J, Anders RA. Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma. Clin Cancer Res. 2012 Mar 01; 18(5):1291-302.
PMID:
21868763
; PMCID:
PMC3233659
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Kwei KA, Shain AH, Bair R, Montgomery K, Karikari CA, van de Rijn M, Hidalgo M,
Maitra A
, Bashyam MD, Pollack JR. SMURF1 amplification promotes invasiveness in pancreatic cancer. PLoS One. 2011; 6(8):e23924.
PMID:
21887346
; PMCID:
PMC3161761
.
Citations:
26
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Caldwell ME, DeNicola GM, Martins CP, Jacobetz MA,
Maitra A
, Hruban RH, Tuveson DA. Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer. Oncogene. 2012 Mar 22; 31(12):1599-608.
PMID:
21860420
; PMCID:
PMC3397306
.
Citations:
37
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Animals
Wu J, Matthaei H,
Maitra A
, Dal Molin M, Wood LD, Eshleman JR, Goggins M, Canto MI, Schulick RD, Edil BH, Wolfgang CL, Klein AP, Diaz LA, Allen PJ, Schmidt CM, Kinzler KW, Papadopoulos N, Hruban RH, Vogelstein B. Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. Sci Transl Med. 2011 Jul 20; 3(92):92ra66.
PMID:
21775669
; PMCID:
PMC3160649
.
Citations:
318
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Ryu JK, Matthaei H, Dal Molin M, Hong SM, Canto MI, Schulick RD, Wolfgang C, Goggins MG, Hruban RH, Cope L,
Maitra A
. Elevated microRNA miR-21 levels in pancreatic cyst fluid are predictive of mucinous precursor lesions of ductal adenocarcinoma. Pancreatology. 2011; 11(3):343-50.
PMID:
21757972
; PMCID:
PMC3142103
.
Citations:
49
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Garrido-Laguna I, Uson M, Rajeshkumar NV, Tan AC, de Oliveira E, Karikari C, Villaroel MC, Salomon A, Taylor G, Sharma R, Hruban RH,
Maitra A
, Laheru D, Jimeno A, Hidalgo M, Rubio-Viqueira B. Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer. Clin Cancer Res. 2011 Sep 01; 17(17):5793-800.
PMID:
21742805
; PMCID:
PMC3210576
.
Citations:
111
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, Bigner DD, Oba-Shinjo SM, Marie SK, Riggins GJ, Kinzler KW, Vogelstein B, Hruban RH,
Maitra A
, Papadopoulos N, Meeker AK. Altered telomeres in tumors with ATRX and DAXX mutations. Science. 2011 Jul 22; 333(6041):425.
PMID:
21719641
; PMCID:
PMC3174141
.
Citations:
472
Fields:
Sci
Science
Translation:
Humans
Cells
Matthaei H, Hong SM, Mayo SC, Dal Molin M, Olino K, Venkat R, Goggins M, Herman JM, Edil BH, Wolfgang CL, Cameron JL, Schulick RD,
Maitra A
, Hruban RH. Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer. Indian J Surg Oncol. 2011 Mar; 2(1):9-15.
PMID:
22696140
; PMCID:
PMC3373004
.
Citations:
1
Fishel ML, Jiang Y, Rajeshkumar NV, Scandura G, Sinn AL, He Y, Shen C, Jones DR, Pollok KE, Ivan M,
Maitra A
, Kelley MR. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth. Mol Cancer Ther. 2011 Sep; 10(9):1698-708.
PMID:
21700832
; PMCID:
PMC3170439
.
Citations:
52
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Bisht S, Khan MA, Bekhit M, Bai H, Cornish T, Mizuma M, Rudek MA, Zhao M, Maitra A, Ray B, Lahiri D,
Maitra A
, Anders RA. A polymeric nanoparticle formulation of curcumin (NanoCurc?) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation. Lab Invest. 2011 Sep; 91(9):1383-95.
PMID:
21691262
; PMCID:
PMC3345948
.
Citations:
39
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Animals
Cells
Feldmann G, Karikari C, dal Molin M, Duringer S, Volkmann P, Bartsch DK, Bisht S, Koorstra JB, Brossart P,
Maitra A
, Fendrich V. Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancer. Cancer Biol Ther. 2011 Jun 01; 11(11):959-68.
PMID:
21455033
; PMCID:
PMC3127047
.
Citations:
14
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Animals
Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT,
Maitra A
. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther. 2011 Aug; 10(8):1470-80.
PMID:
21622730
; PMCID:
PMC3154495
.
Citations:
152
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Matthaei H, Hong SM, Mayo SC, dal Molin M, Olino K, Venkat R, Goggins M, Herman JM, Edil BH, Wolfgang CL, Cameron JL, Schulick RD,
Maitra A
, Hruban RH. Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer. Ann Surg Oncol. 2011 Nov; 18(12):3493-9.
PMID:
21537863
; PMCID:
PMC3166423
.
Citations:
22
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Zheng L, Foley K, Huang L, Leubner A, Mo G, Olino K, Edil BH, Mizuma M, Sharma R, Le DT, Anders RA, Illei PB, Van Eyk JE,
Maitra A
, Laheru D, Jaffee EM. Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. PLoS One. 2011 Apr 29; 6(4):e19390.
PMID:
21572519
; PMCID:
PMC3084841
.
Citations:
97
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Alvarez H, Opalinska J, Zhou L, Sohal D, Fazzari MJ, Yu Y, Montagna C, Montgomery EA, Canto M, Dunbar KB, Wang J, Roa JC, Mo Y, Bhagat T, Ramesh KH, Cannizzaro L, Mollenhauer J, Thompson RF, Suzuki M, Meltzer SJ, Meltzer S, Melnick A, Greally JM,
Maitra A
, Verma A. Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis. PLoS Genet. 2011 Mar; 7(3):e1001356.
PMID:
21483804
; PMCID:
PMC3069107
.
Citations:
64
Fields:
Gen
Genetics
Translation:
Humans
Cells
Ottenhof NA, de Wilde RF,
Maitra A
, Hruban RH, Offerhaus GJ. Molecular characteristics of pancreatic ductal adenocarcinoma. Patholog Res Int. 2011 Mar 27; 2011:620601.
PMID:
21512581
; PMCID:
PMC3068308
.
Citations:
23
Rajeshkumar NV, De Oliveira E, Ottenhof N, Watters J, Brooks D, Demuth T, Shumway SD, Mizuarai S, Hirai H,
Maitra A
, Hidalgo M. MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts. Clin Cancer Res. 2011 May 01; 17(9):2799-806.
PMID:
21389100
; PMCID:
PMC3307341
.
Citations:
127
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Matthaei H, Schulick RD, Hruban RH,
Maitra A
. Cystic precursors to invasive pancreatic cancer. Nat Rev Gastroenterol Hepatol. 2011 Mar; 8(3):141-50.
PMID:
21383670
; PMCID:
PMC3236705
.
Citations:
87
Fields:
Gas
Gastroenterology
Translation:
Humans
Chiu SS, Lui E, Majeed M, Vishwanatha JK, Ranjan AP,
Maitra A
, Pramanik D, Smith JA, Helson L. Differential distribution of intravenous curcumin formulations in the rat brain. Anticancer Res. 2011 Mar; 31(3):907-11.
PMID:
21498712
; PMCID:
PMC3568517
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Animals
Lim KJ, Bisht S, Bar EE,
Maitra A
, Eberhart CG. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol Ther. 2011 Mar 01; 11(5):464-73.
PMID:
21193839
; PMCID:
PMC3087900
.
Citations:
62
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Fendrich V, Schneider R,
Maitra A
, Jacobsen ID, Opfermann T, Bartsch DK. Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer. Neoplasia. 2011 Feb; 13(2):180-6.
PMID:
21403843
; PMCID:
PMC3033596
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Jiao Y, Shi C, Edil BH, de Wilde RF, Klimstra DS,
Maitra A
, Schulick RD, Tang LH, Wolfgang CL, Choti MA, Velculescu VE, Diaz LA, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N. DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science. 2011 Mar 04; 331(6021):1199-203.
PMID:
21252315
; PMCID:
PMC3144496
.
Citations:
702
Fields:
Sci
Science
Translation:
Humans
Cells
Wang Q, Chaerkady R, Wu J, Hwang HJ, Papadopoulos N, Kopelovich L,
Maitra A
, Matthaei H, Eshleman JR, Hruban RH, Kinzler KW, Pandey A, Vogelstein B. Mutant proteins as cancer-specific biomarkers. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2444-9.
PMID:
21248225
; PMCID:
PMC3038743
.
Citations:
71
Fields:
Sci
Science
Translation:
Humans
Cells
Ray B, Bisht S, Maitra A,
Maitra A
, Lahiri DK. Neuroprotective and neurorescue effects of a novel polymeric nanoparticle formulation of curcumin (NanoCurc?) in the neuronal cell culture and animal model: implications for Alzheimer's disease. J Alzheimers Dis. 2011; 23(1):61-77.
PMID:
20930270
; PMCID:
PMC3303195
.
Citations:
54
Fields:
Ger
Geriatrics
Neu
Neurology
Translation:
Humans
Animals
Cells
Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD,
Maitra A
, Mendell JT. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev. 2010 Dec 15; 24(24):2754-9.
PMID:
21159816
; PMCID:
PMC3003192
.
Citations:
163
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Villarroel MC, Rajeshkumar NV, Garrido-Laguna I, De Jesus-Acosta A,
Maitra A
, Hruban RH, Eshleman JR, Klein A, Laheru D, Donehower R, Hidalgo M, Jones S. Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer. Mol Cancer Ther. 2011 Jan; 10(1):3-8.
PMID:
21135251
; PMCID:
PMC3307340
.
Citations:
123
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
CT
Clinical Trials
Bisht S, Brossart P,
Maitra A
, Feldmann G. Agents targeting the Hedgehog pathway for pancreatic cancer treatment. Curr Opin Investig Drugs. 2010 Dec; 11(12):1387-98.
PMID:
21154121
.
Citations:
11
Fields:
Dru
Drug Therapy
Translation:
Humans
Cells
Hector A, Montgomery EA, Karikari C, Canto M, Dunbar KB, Wang JS, Feldmann G, Hong SM, Haffner MC, Meeker AK, Holland SJ, Yu J, Heckrodt TJ, Zhang J, Ding P, Goff D, Singh R, Roa JC, Marimuthu A, Riggins GJ, Eshleman JR, Nelkin BD, Pandey A,
Maitra A
. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer Biol Ther. 2010 Nov 15; 10(10):1009-18.
PMID:
20818175
; PMCID:
PMC3025816
.
Citations:
55
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Cai J, Zhang N, Zheng Y, de Wilde RF,
Maitra A
, Pan D. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev. 2010 Nov 01; 24(21):2383-8.
PMID:
21041407
; PMCID:
PMC2964748
.
Citations:
241
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Liby KT, Royce DB, Risingsong R, Williams CR,
Maitra A
, Hruban RH, Sporn MB. Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer. Cancer Prev Res (Phila). 2010 Nov; 3(11):1427-34.
PMID:
20959520
; PMCID:
PMC2988079
.
Citations:
49
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Ishizawa K, Rasheed ZA, Karisch R, Wang Q, Kowalski J, Susky E, Pereira K, Karamboulas C, Moghal N, Rajeshkumar NV, Hidalgo M, Tsao M, Ailles L, Waddell TK,
Maitra A
, Neel BG, Matsui W. Tumor-initiating cells are rare in many human tumors. Cell Stem Cell. 2010 Sep 03; 7(3):279-82.
PMID:
20804964
; PMCID:
PMC2945729
.
Citations:
112
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Shi C, Siegelman SS, Kawamoto S, Wolfgang CL, Schulick RD,
Maitra A
, Hruban RH. Pancreatic duct stenosis secondary to small endocrine neoplasms: a manifestation of serotonin production? Radiology. 2010 Oct; 257(1):107-14.
PMID:
20713615
; PMCID:
PMC2941724
.
Citations:
16
Fields:
Rad
Radiology
Translation:
Humans
Bisht S, Mizuma M, Feldmann G, Ottenhof NA, Hong SM, Pramanik D, Chenna V, Karikari C, Sharma R, Goggins MG, Rudek MA, Ravi R, Maitra A,
Maitra A
. Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer. Mol Cancer Ther. 2010 Aug; 9(8):2255-64.
PMID:
20647339
; PMCID:
PMC2942082
.
Citations:
57
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Feldmann G, Mishra A, Hong SM, Bisht S, Strock CJ, Ball DW, Goggins M,
Maitra A
, Nelkin BD. Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling. Cancer Res. 2010 Jun 01; 70(11):4460-9.
PMID:
20484029
; PMCID:
PMC3071300
.
Citations:
90
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ryu JK, Hong SM, Karikari CA, Hruban RH, Goggins MG,
Maitra A
. Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma. Pancreatology. 2010; 10(1):66-73.
PMID:
20332664
; PMCID:
PMC2865485
.
Citations:
64
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Kamiyama H, Kamiyama M, Hong SM, Karikari CA, Lin MT, Borges MW, Griffith M, Young A, Norris-Kirby A, Lubek C, Mizuma M, Feldmann G, Shi C, Liang H, Goggins MG,
Maitra A
, Hruban RH, Eshleman JR. In vivo and in vitro propagation of intraductal papillary mucinous neoplasms. Lab Invest. 2010 May; 90(5):665-73.
PMID:
20231822
; PMCID:
PMC2885280
.
Citations:
7
Fields:
Cli
Clinical Laboratory Techniques
Pat
Pathology
Translation:
Humans
Animals
Cells
Rasheed ZA, Yang J, Wang Q, Kowalski J, Freed I, Murter C, Hong SM, Koorstra JB, Rajeshkumar NV, He X, Goggins M, Iacobuzio-Donahue C, Berman DM, Laheru D, Jimeno A, Hidalgo M,
Maitra A
, Matsui W. Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma. J Natl Cancer Inst. 2010 Mar 03; 102(5):340-51.
PMID:
20164446
; PMCID:
PMC2831049
.
Citations:
204
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Maitra A
. Tracking down the hedgehog's lair in the pancreas. Gastroenterology. 2010 Mar; 138(3):823-5.
PMID:
20100446
; PMCID:
PMC3025814
.
Citations:
3
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Le A, Cooper CR, Gouw AM, Dinavahi R,
Maitra A
, Deck LM, Royer RE, Vander Jagt DL, Semenza GL, Dang CV. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci U S A. 2010 Feb 02; 107(5):2037-42.
PMID:
20133848
; PMCID:
PMC2836706
.
Citations:
564
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Shi C, Klein AP, Goggins M,
Maitra A
, Canto M, Ali S, Schulick R, Palmisano E, Hruban RH. Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients. Clin Cancer Res. 2009 Dec 15; 15(24):7737-7743.
PMID:
19996207
; PMCID:
PMC2795080
.
Citations:
83
Fields:
Neo
Neoplasms
Maitra A
, Hidalgo M. The hedgehog pathway and pancreatic cancer. N Engl J Med. 2009 Nov 19; 361(21):2094-6.
PMID:
19923581
.
Citations:
43
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Fendrich V, Chen NM, Neef M, Waldmann J, Buchholz M, Feldmann G, Slater EP,
Maitra A
, Bartsch DK. The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer. Gut. 2010 May; 59(5):630-7.
PMID:
19880966
.
Citations:
41
Fields:
Gas
Gastroenterology
Translation:
Animals
Kent OA, Mullendore M, Wentzel EA, Tan AC, Alvarez H, West K, Ochs MF, Hidalgo M, Arking DE,
Maitra A
, Mendell JT, L?pez-Romero P. A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. Cancer Biol Ther. 2009 Nov; 8(21):2013-24.
PMID:
20037478
; PMCID:
PMC2824894
.
Citations:
66
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Hristov AC, Cope L, Di Cello F, Reyes MD, Singh M, Hillion JA, Belton A, Joseph B, Schuldenfrei A, Iacobuzio-Donahue CA,
Maitra A
, Resar LM. HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma. Mod Pathol. 2010 Jan; 23(1):98-104.
PMID:
19820691
; PMCID:
PMC3092591
.
Citations:
42
Fields:
Pat
Pathology
Translation:
Humans
Shi C, Chandrasekaran A, Thuluvath PJ, Karikari C, Argani P, Goggins M,
Maitra A
, Eshleman JR. Ultrasensitive detection of KRAS2 mutations in bile and serum from patients with biliary tract carcinoma using LigAmp technology. J Mol Diagn. 2009 Nov; 11(6):583-9.
PMID:
19815696
; PMCID:
PMC2765758
.
Citations:
4
Fields:
Mol
Molecular Biology
Translation:
Humans
Wu JM, Alvarez H, Rojas PL, Wong G,
Maitra A
, Antonescu C, Montgomery EA, Garc?a P. Melanoma hyperpigmentation is strongly associated with KIT alterations. Am J Dermatopathol. 2009 Oct; 31(7):619-25.
PMID:
19652585
.
Citations:
1
Fields:
Der
Dermatology
Pat
Pathology
Translation:
Humans
Bisht S,
Maitra A
. Systemic delivery of curcumin: 21st century solutions for an ancient conundrum. Curr Drug Discov Technol. 2009 Sep; 6(3):192-9.
PMID:
19496751
.
Citations:
36
Fields:
Pha
Pharmacology
Translation:
Humans
Animals
Koorstra JB, Hong SM, Shi C, Meeker AK, Ryu JK, Offerhaus GJ, Goggins MG, Hruban RH,
Maitra A
. Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia. Mod Pathol. 2009 Nov; 22(11):1439-45.
PMID:
19668150
; PMCID:
PMC2784029
.
Citations:
19
Fields:
Pat
Pathology
Translation:
Humans
Cells
Blackford A, Serrano OK, Wolfgang CL, Parmigiani G, Zhang X,
Parsons DW
, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA,
Maitra A
, Cameron JL, Olino K, Schulick R, Winter J, Herman JM, Laheru D, Klein AP, Vogelstein B, Kinzler KW, Velculescu VE, Hruban RH, Jones S. SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer. Clin Cancer Res. 2009 Jul 15; 15(14):4674-9.
PMID:
19584151
; PMCID:
PMC2819274
.
Citations:
168
Fields:
Neo
Neoplasms
Translation:
Humans
Selaru FM, Olaru AV, Kan T, David S, Cheng Y, Mori Y, Yang J, Paun B, Jin Z, Agarwal R, Hamilton JP, Abraham J, Georgiades C, Alvarez H, Vivekanandan P, Yu W,
Maitra A
, Torbenson M, Thuluvath PJ, Gores GJ, LaRusso NF, Hruban R, Meltzer SJ. MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3. Hepatology. 2009 May; 49(5):1595-601.
PMID:
19296468
; PMCID:
PMC3124086
.
Citations:
139
Fields:
Gas
Gastroenterology
Translation:
Humans
Cells
Scudiere JR,
Maitra A
, Montgomery EA. Selected topics in the evaluation of pediatric gastrointestinal mucosal biopsies. Adv Anat Pathol. 2009 May; 16(3):154-60.
PMID:
19395878
.
Citations:
Fields:
Ana
Anatomy
Pat
Pathology
Translation:
Humans
Lee KH, Lotterman C, Karikari C, Omura N, Feldmann G, Habbe N, Goggins MG, Mendell JT,
Maitra A
. Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology. 2009; 9(3):293-301.
PMID:
19407485
; PMCID:
PMC2835374
.
Citations:
101
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Cells
Koorstra JB, Karikari CA, Feldmann G, Bisht S, Rojas PL, Offerhaus GJ, Alvarez H,
Maitra A
. The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target. Cancer Biol Ther. 2009 Apr; 8(7):618-26.
PMID:
19252414
; PMCID:
PMC2678175
.
Citations:
88
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Zhang X,
Parsons DW
, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA,
Maitra A
, Klein A, Cameron JL, Olino K, Schulick R, Winter J, Vogelstein B, Velculescu VE, Kinzler KW, Hruban RH, Jones S. Genetic mutations associated with cigarette smoking in pancreatic cancer. Cancer Res. 2009 Apr 15; 69(8):3681-8.
PMID:
19351817
; PMCID:
PMC2669837
.
Citations:
51
Fields:
Neo
Neoplasms
Translation:
Humans
Zou GM, Karikari C, Kabe Y, Handa H, Anders RA,
Maitra A
. The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis. J Cell Physiol. 2009 Apr; 219(1):209-18.
PMID:
19097035
.
Citations:
40
Fields:
Cel
Cell Biology
Phy
Physiology
Translation:
Humans
Animals
Cells
Feldmann G, Rauenzahn S,
Maitra A
. In vitro models of pancreatic cancer for translational oncology research. Expert Opin Drug Discov. 2009 Apr 01; 4(4):429-443.
PMID:
20160967
; PMCID:
PMC2760831
.
Citations:
19
Fields:
Che
Chemistry Techniques
Pha
Pharmacology
Yong KT, Ding H, Roy I, Law WC, Bergey EJ,
Maitra A
, Prasad PN. Imaging pancreatic cancer using bioconjugated InP quantum dots. ACS Nano. 2009 Mar 24; 3(3):502-10.
PMID:
19243145
; PMCID:
PMC2762404
.
Citations:
59
Fields:
Nan
Nanotechnology
Translation:
Humans
Cells
Hruban RH, Kamiyama M, Borges M, Zhang X,
Parsons DW
, Lin JC, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA,
Maitra A
, Parmigiani G, Kern SE, Velculescu VE, Kinzler KW, Vogelstein B, Eshleman JR, Goggins M, Klein AP, Jones S. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science. 2009 Apr 10; 324(5924):217.
PMID:
19264984
; PMCID:
PMC2684332
.
Citations:
358
Fields:
Sci
Science
Translation:
Humans
Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, Matsui W, Eberhart CG,
Maitra A
, Feldmann G. Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clin Cancer Res. 2009 Apr 01; 15(7):2291-301.
PMID:
19258443
; PMCID:
PMC2711441
.
Citations:
88
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Yong KT, Hu R, Roy I, Ding H, Vathy LA, Bergey EJ, Mizuma M,
Maitra A
, Prasad PN. Tumor targeting and imaging in live animals with functionalized semiconductor quantum rods. ACS Appl Mater Interfaces. 2009 Mar; 1(3):710-9.
PMID:
20160901
; PMCID:
PMC2768400
.
Citations:
16
Fields:
Bio
Biomedical Engineering
Bio
Biotechnology
Translation:
Animals
Ottenhof NA, Milne AN, Morsink FH, Drillenburg P, Ten Kate FJ,
Maitra A
, Offerhaus GJ. Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis: of mice and men. Arch Pathol Lab Med. 2009 Mar; 133(3):375-81.
PMID:
19260743
.
Citations:
22
Fields:
Pat
Pathology
Translation:
Humans
Animals
Habbe N, Koorstra JB, Mendell JT, Offerhaus GJ, Ryu JK, Feldmann G, Mullendore ME, Goggins MG, Hong SM,
Maitra A
. MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biol Ther. 2009 Feb; 8(4):340-6.
PMID:
19106647
; PMCID:
PMC2692997
.
Citations:
138
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Anders RA, Montgomery E,
Maitra A
. Johns Hopkins course: 8th annual Current Topics in Gastrointestinal and Liver Pathology. Expert Rev Gastroenterol Hepatol. 2009 Feb; 3(1):33-7.
PMID:
19210111
.
Citations:
Fields:
Gas
Gastroenterology
Translation:
Humans
Jimeno A, Feldmann G, Rasheed Z, Solomon A, Zou GM, Rubio-Viqueira B, Matsui W,
Maitra A
, Hidalgo M, Su?rez-Gauthier A, Garc?a-Garc?a E, L?pez-R?os F. A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development. Mol Cancer Ther. 2009 Feb; 8(2):310-4.
PMID:
19174553
; PMCID:
PMC3033101
.
Citations:
134
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Boozer S, Lehman N, Lakshmipathy U, Love B, Raber A,
Maitra A
, Deans R, Rao MS, Ting AE. Global Characterization and Genomic Stability of Human MultiStem, A Multipotent Adult Progenitor Cell. J Stem Cells. 2009; 4(1):17-28.
PMID:
20498688
.
Citations:
31
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Koorstra JB,
Maitra A
, Morsink FH, Drillenburg P, ten Kate FJ, Hruban RH, Offerhaus JA. Undifferentiated carcinoma with osteoclastic giant cells (UCOCGC) of the pancreas associated with the familial atypical multiple mole melanoma syndrome (FAMMM). Am J Surg Pathol. 2008 Dec; 32(12):1905-9.
PMID:
18813118
; PMCID:
PMC2704013
.
Citations:
11
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Cells
Bisht S, Feldmann G, Koorstra JB, Mullendore M, Alvarez H, Karikari C, Rudek MA, Lee CK, Maitra A,
Maitra A
. In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities. Mol Cancer Ther. 2008 Dec; 7(12):3878-88.
PMID:
19074860
; PMCID:
PMC4517597
.
Citations:
20
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Animals
Cells
Habbe N, Shi G, Meguid RA, Fendrich V, Esni F, Chen H, Feldmann G, Stoffers DA, Konieczny SF, Leach SD,
Maitra A
. Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18913-8.
PMID:
19028870
; PMCID:
PMC2596215
.
Citations:
205
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Chen S, Auletta T, Dovirak O, Hutter C, Kuntz K, El-ftesi S, Kendall J, Han H, Von Hoff DD, Ashfaq R,
Maitra A
, Iacobuzio-Donahue CA, Hruban RH, Lucito R. Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification. Cancer Biol Ther. 2008 Nov; 7(11):1793-802.
PMID:
18836286
; PMCID:
PMC7323936
.
Citations:
58
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Alvarez H, Koorstra JB, Hong SM, Boonstra JJ, Dinjens WN, Foratiere AA, Wu TT, Montgomery E, Eshleman JR,
Maitra A
. Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line. Cancer Biol Ther. 2008 Nov; 7(11):1753-5.
PMID:
18787394
; PMCID:
PMC3596869
.
Citations:
29
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Cheung W, Darfler MM, Alvarez H, Hood BL, Conrads TP, Habbe N, Krizman DB, Mollenhauer J, Feldmann G,
Maitra A
. Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors. Pancreatology. 2008; 8(6):608-16.
PMID:
18849643
; PMCID:
PMC2711211
.
Citations:
23
Fields:
End
Endocrinology
Gas
Gastroenterology
Translation:
Humans
Cells
Kristiansen TZ, Harsha HC,
Maitra A
, Pandey A, Gr?nborg M. Differential membrane proteomics using 18O-labeling to identify biomarkers for cholangiocarcinoma. J Proteome Res. 2008 Nov; 7(11):4670-7.
PMID:
18839982
; PMCID:
PMC3204659
.
Citations:
17
Fields:
Bio
Biochemistry
Translation:
Humans