TitleAssistant Professor
InstitutionMD Anderson
DepartmentClinical Cancer Prevention
Address1155 Pressler St
Houston TX 77030-3721
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kneuertz PJ, Chang GJ, Hu CY, Rodriguez-Bigas MA, Eng C, Vilar E, Skibber JM, Feig BW, Cormier JN, You YN. Overtreatment of young adults with colon cancer: more intense treatments with unmatched survival gains. JAMA Surg. 2015 May; 150(5):402-9. PMID: 25806815.
      Citations: 58     Fields:    Translation:HumansCTClinical Trials
    2. Morris V, Overman MJ, Eng C, Garrett CR, Boutin AT, Ferrarotto R, Lee M, Jiang ZQ, Vauthey JN, Vilar E, Maru D, Kopetz S, Pereira AA, Rego JF, Hoff PM. Association between KRAS mutation and lung metastasis in advanced colorectal cancer. Br J Cancer. 2015 Feb 03; 112(3):424-8. PMID: 25535726; PMCID: PMC4453646.
      Citations: 40     Fields:    Translation:Humans
    3. San Lucas FA, Fowler J, Chang K, Kopetz S, Vilar E, Scheet P. Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypes. Mol Cancer Ther. 2014 Dec; 13(12):3230-40. PMID: 25349306; PMCID: PMC4341901.
      Citations: 5     Fields:    Translation:HumansCells
    4. Vilar E, Mork ME, Cuddy A, Borras E, Bannon SA, Taggart MW, Ying J, Broaddus RR, Luthra R, Rodriguez-Bigas MA, Lynch PM, You YQ. Role of microsatellite instability-low as a diagnostic biomarker of Lynch syndrome in colorectal cancer. Cancer Genet. 2014 Oct-Dec; 207(10-12):495-502. PMID: 25432668; PMCID: PMC4278939.
      Citations: 6     Fields:    Translation:Humans
    5. Colbert Maresso K, Vilar E, Hawk ET. Urinary PGE-M in colorectal cancer: predicting more than risk? Cancer Prev Res (Phila). 2014 Oct; 7(10):969-72. PMID: 25070664; PMCID: PMC4185234.
      Citations: 6     Fields:    Translation:Humans
    6. Morris VK, Lucas FAS, Overman MJ, Eng C, Morelli MP, Jiang ZQ, Luthra R, Meric-Bernstam F, Maru D, Scheet P, Kopetz S, Vilar E. Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer. Ann Oncol. 2014 Oct; 25(10):2008-2014. PMID: 25009008; PMCID: PMC4176451.
      Citations: 29     Fields:    Translation:Humans
    7. Goldstein J, Tran B, Ensor J, Gibbs P, Wong HL, Wong SF, Vilar E, Tie J, Broaddus R, Kopetz S, Desai J, Overman MJ. Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H). Ann Oncol. 2014 May; 25(5):1032-8. PMID: 24585723; PMCID: PMC4072907.
      Citations: 97     Fields:    Translation:Humans
    8. Borras E, Taggart MW, Lynch PM, Vilar E. Establishing a diagnostic road map for MUTYH-associated polyposis. Clin Cancer Res. 2014 Mar 01; 20(5):1061-3. PMID: 24486588; PMCID: PMC3996649.
      Citations: 1     Fields:    Translation:Humans
    9. Diaz-Padilla I, Romero N, Amir E, Matias-Guiu X, Vilar E, Muggia F, Garcia-Donas J. Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol. 2013 Oct; 88(1):154-67. PMID: 23562498.
      Citations: 40     Fields:    Translation:HumansCells
    10. You YN, Vilar E. Classifying MMR variants: time for revised nomenclature in Lynch syndrome. Clin Cancer Res. 2013 May 01; 19(9):2280-2. PMID: 23532885; PMCID: PMC3854938.
      Citations: 4     Fields:    Translation:Humans
    11. Vilar E, Tabernero J. Molecular dissection of microsatellite instable colorectal cancer. Cancer Discov. 2013 May; 3(5):502-11. PMID: 23454900; PMCID: PMC3651752.
      Citations: 47     Fields:    Translation:Humans
    12. Vilar E, Tabernero J. Cancer: Pinprick diagnostics. Nature. 2012 Jun 27; 486(7404):482-3. PMID: 22739312.
      Citations: 7     Fields:    Translation:Humans
    13. Vilar E, Tabernero J, Gruber SB. Micromanaging the classification of colon cancer: the role of the microRNAome. Clin Cancer Res. 2011 Dec 01; 17(23):7207-9. PMID: 22019515; PMCID: PMC3422018.
      Citations: 7     Fields:    Translation:HumansCells
    14. Vilar E, Tabernero J, Dienstmann R. Molecular predictors of response to chemotherapy in colorectal cancer. Cancer J. 2011 Mar-Apr; 17(2):114-26. PMID: 21427555.
      Citations: 16     Fields:    Translation:Humans
    15. Vilar E, Bartnik CM, Stenzel SL, Raskin L, Ahn J, Moreno V, Mukherjee B, Iniesta MD, Morgan MA, Rennert G, Gruber SB. MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers. Cancer Res. 2011 Apr 01; 71(7):2632-42. PMID: 21300766; PMCID: PMC3407272.
      Citations: 88     Fields:    Translation:HumansCells
    16. Vilar E, Perez-Garcia J, Tabernero J. Pushing the envelope in the mTOR pathway: the second generation of inhibitors. Mol Cancer Ther. 2011 Mar; 10(3):395-403. PMID: 21216931; PMCID: PMC3413411.
      Citations: 66     Fields:    Translation:HumansCells
    17. Vilar E, Singer H, Salazar R, Iglesias JL, Casado E, Cullell-Young M, Baselga J, Tabernero J, Gr?nwald V, Sch?ffski P. A phase I dose-escalating study of ES-285, a marine sphingolipid-derived compound, with repeat dose administration in patients with advanced solid tumors. Invest New Drugs. 2012 Feb; 30(1):299-305. PMID: 20820909.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    18. Vilar E, Gruber SB. Microsatellite instability in colorectal cancer-the stable evidence. Nat Rev Clin Oncol. 2010 Mar; 7(3):153-62. PMID: 20142816; PMCID: PMC3427139.
      Citations: 313     Fields:    Translation:HumansCells
    19. Capdevila J, Crespo-Herrero G, Villabona-Artero C, Marazuela M, Alvarez-Escola C, Castellano D, Vilar E, Monleon A, Garcia-Carbonero R, D?az-P?rez JA, Mart?nez Del Prado MP, Alonso Ordu?a V, Sevilla-Garc?a I, Beguiristain-G?mez A, Llanos-Mu?oz M, Jim?nez-Fonseca P, Teul? A, Sastre-Valera J, Benavent-Vi?uelas M, Salazar R. Incidence, patterns of care and prognostic factors for outcome of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): results from the National Cancer Registry of Spain (RGETNE). Ann Oncol. 2010 Sep; 21(9):1794-1803. PMID: 20139156.
      Citations: 136     Fields:    Translation:Humans
    20. Vilar E, Mukherjee B, Kuick R, Raskin L, Misek DE, Taylor JM, Giordano TJ, Hanash SM, Fearon ER, Rennert G, Gruber SB. Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. Clin Cancer Res. 2009 Apr 15; 15(8):2829-39. PMID: 19351759; PMCID: PMC3425357.
      Citations: 31     Fields:    Translation:HumansCells
    21. Vilar E, Scaltriti M, Saura C, Guzman M, Arribas J, Baselga J, Tabernero J, Balma?a J. Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. Br J Cancer. 2008 Nov 18; 99(10):1607-12. PMID: 18941461; PMCID: PMC2584960.
      Citations: 34     Fields:    Translation:HumansCells
    22. Vilar E, Cortes J, Oberg K, Tabernero J, Salazar R, P?rez-Garc?a J. Chemotherapy and role of the proliferation marker Ki-67 in digestive neuroendocrine tumors. Endocr Relat Cancer. 2007 Jun; 14(2):221-32. PMID: 17639039.
      Citations: 52     Fields:    Translation:Humans
    23. Salazar R, Casanovas O, Arrazubi V, Vilar E, Siu LL, Yao J, Tabernero J, Dur?n I. New drug development in digestive neuroendocrine tumors. Ann Oncol. 2007 Aug; 18(8):1307-13. PMID: 17301070.
      Citations: 7     Fields:    Translation:HumansAnimals
    24. del Campo JM, Vilar E. [New challenges for molecular oncology in ovarian carcinoma]. Med Clin (Barc). 2007 Jan 13; 128(1):15-7. PMID: 17266887.
      Citations:    Fields:    Translation:Humans
    25. Vilar E, Calvo E, Tabernero J. Molecular biology of testicular germ cell tumors. Clin Transl Oncol. 2006 Dec; 8(12):846-50. PMID: 17169757.
      Citations: 1     Fields:    Translation:Humans
    26. Felip E, Vilar E. The expanding role of systemic treatment in non-small cell lung cancer neo-adjuvant therapy. Ann Oncol. 2006 Sep; 17 Suppl 10:x108-12. PMID: 17018710.
      Citations: 1     Fields:    Translation:Humans
    27. Vilar E, Balma?a J, Esp?n E. BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors. Cancer. 2006 Jun 01; 106(11):2528-9; author reply 2529. PMID: 16628650.
      Citations:    Fields:    Translation:HumansCells
    28. Vilar E, Tabernero J, Casado E, Macarulla T, Ramos FJ, Martinelli E, Saura C. Lack of efficacy of streptozocin and doxorubicin in patients with advanced pancreatic endocrine tumors. Am J Clin Oncol. 2005 Aug; 28(4):424. PMID: 16062087.
      Citations:    Fields:    Translation:Humans
    29. Identification of a novel PMS2 alteration c.505C>G (R169G) in trans with a PMS2 pathogenic mutation in a patient with constitutional mismatch repair deficiency. Familial Cancer. 1-5.
    30. Oncogenic targets Mmp7, S100a9, Nppb and Aldh1a3 from transcriptome profiling of FAP and Pirc adenomas are downregulated in response to tumor suppression by Clotam. International Journal of Cancer.
    31. Reply to L.B. Saltz. Journal of Clinical Oncology. 34:1560.
    32. DNA Mismatch Repair Deficiency in Rectal Cancer. Journal of Clinical Oncology. 34:3039-3046.
    33. Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials. Annals of Oncology. 27:1068-1074.
    34. Patient-reported disease knowledge and educational needs in Lynch syndrome. Hereditary Cancer in Clinical Practice. 12.
    35. Embarazo ectopico. Ciencia Ginecologika. 3:241-246.
    36. Leveraging premalignant biology for immune-based cancer prevention. Proceedings of the National Academy of Sciences of the United States of America. 113:10750-10758.
    37. Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment. Annals of Oncology. 26:731-736.
    38. Perspectivas actuales del diagnóstico prenatal. Ciencia Ginecologika. 5:137-138.
    39. Fibrosis quística y contracepción. Toko-Ginecologia Practica. 60:24-29.
    40. Familial Cancer. 1-5.
    41. Genomic landscape of colorectal mucosa and adenomas. Cancer Prevention Research. 9:417-427.
    42. High prevalence of hereditary cancer syndromes in adolescents and young adults with colorectal cancer. Journal of Clinical Oncology. 33:3544-3549.
    43. Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq. Bioinformatics. 32:3015-3017.
    44. Molecular markers in colorectal cancer. Colorectal Cancer. 2:243-263.
    45. MUTYH-associated polyposis. 25-32.
    46. Spontaneous hematoma of the abdominal wall in pregnancy. Journal of Gynecologic Surgery. 18:105-107.
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