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EDUARDO VILAR SANCHEZ

TitleAssistant Professor
InstitutionMD Anderson
DepartmentClinical Cancer Prevention
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kneuertz PJ, Chang GJ, Hu CY, Rodriguez-Bigas MA, Eng C, Vilar E, Skibber JM, Feig BW, Cormier JN, You YN. Overtreatment of young adults with colon cancer: more intense treatments with unmatched survival gains. JAMA Surg. 2015 May; 150(5):402-9. PMID: 25806815.
      View in: PubMed
    2. Pereira AA, Rego JF, Morris V, Overman MJ, Eng C, Garrett CR, Boutin AT, Ferrarotto R, Lee M, Jiang ZQ, Hoff PM, Vauthey JN, Vilar E, Maru D, Kopetz S. Association between KRAS mutation and lung metastasis in advanced colorectal cancer. Br J Cancer. 2015 Feb 03; 112(3):424-8. PMID: 25535726.
      View in: PubMed
    3. San Lucas FA, Fowler J, Chang K, Kopetz S, Vilar E, Scheet P. Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypes. Mol Cancer Ther. 2014 Dec; 13(12):3230-40. PMID: 25349306.
      View in: PubMed
    4. Vilar E, Mork ME, Cuddy A, Borras E, Bannon SA, Taggart MW, Ying J, Broaddus RR, Luthra R, Rodriguez-Bigas MA, Lynch PM, You YQ. Role of microsatellite instability-low as a diagnostic biomarker of Lynch syndrome in colorectal cancer. Cancer Genet. 2014 Oct-Dec; 207(10-12):495-502. PMID: 25432668.
      View in: PubMed
    5. Colbert Maresso K, Vilar E, Hawk ET. Urinary PGE-M in colorectal cancer: predicting more than risk? Cancer Prev Res (Phila). 2014 Oct; 7(10):969-72. PMID: 25070664.
      View in: PubMed
    6. Morris VK, Lucas FA, Overman MJ, Eng C, Morelli MP, Jiang ZQ, Luthra R, Meric-Bernstam F, Maru D, Scheet P, Kopetz S, Vilar E. Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer. Ann Oncol. 2014 Oct; 25(10):2008-14. PMID: 25009008.
      View in: PubMed
    7. Goldstein J, Tran B, Ensor J, Gibbs P, Wong HL, Wong SF, Vilar E, Tie J, Broaddus R, Kopetz S, Desai J, Overman MJ. Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H). Ann Oncol. 2014 May; 25(5):1032-8. PMID: 24585723.
      View in: PubMed
    8. Borras E, Taggart MW, Lynch PM, Vilar E. Establishing a diagnostic road map for MUTYH-associated polyposis. Clin Cancer Res. 2014 Mar 01; 20(5):1061-3. PMID: 24486588.
      View in: PubMed
    9. Diaz-Padilla I, Romero N, Amir E, Matias-Guiu X, Vilar E, Muggia F, Garcia-Donas J. Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol. 2013 Oct; 88(1):154-67. PMID: 23562498.
      View in: PubMed
    10. You YN, Vilar E. Classifying MMR variants: time for revised nomenclature in Lynch syndrome. Clin Cancer Res. 2013 May 01; 19(9):2280-2. PMID: 23532885.
      View in: PubMed
    11. Vilar E, Tabernero J. Molecular dissection of microsatellite instable colorectal cancer. Cancer Discov. 2013 May; 3(5):502-11. PMID: 23454900.
      View in: PubMed
    12. Vilar E, Tabernero J. Cancer: Pinprick diagnostics. Nature. 2012 Jun 27; 486(7404):482-3. PMID: 22739312.
      View in: PubMed
    13. Vilar E, Tabernero J, Gruber SB. Micromanaging the classification of colon cancer: the role of the microRNAome. Clin Cancer Res. 2011 Dec 01; 17(23):7207-9. PMID: 22019515.
      View in: PubMed
    14. Dienstmann R, Vilar E, Tabernero J. Molecular predictors of response to chemotherapy in colorectal cancer. Cancer J. 2011 Mar-Apr; 17(2):114-26. PMID: 21427555.
      View in: PubMed
    15. Vilar E, Bartnik CM, Stenzel SL, Raskin L, Ahn J, Moreno V, Mukherjee B, Iniesta MD, Morgan MA, Rennert G, Gruber SB. MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers. Cancer Res. 2011 Apr 01; 71(7):2632-42. PMID: 21300766.
      View in: PubMed
    16. Vilar E, Perez-Garcia J, Tabernero J. Pushing the envelope in the mTOR pathway: the second generation of inhibitors. Mol Cancer Ther. 2011 Mar; 10(3):395-403. PMID: 21216931.
      View in: PubMed
    17. Vilar E, Grünwald V, Schöffski P, Singer H, Salazar R, Iglesias JL, Casado E, Cullell-Young M, Baselga J, Tabernero J. A phase I dose-escalating study of ES-285, a marine sphingolipid-derived compound, with repeat dose administration in patients with advanced solid tumors. Invest New Drugs. 2012 Feb; 30(1):299-305. PMID: 20820909.
      View in: PubMed
    18. Vilar E, Gruber SB. Microsatellite instability in colorectal cancer-the stable evidence. Nat Rev Clin Oncol. 2010 Mar; 7(3):153-62. PMID: 20142816.
      View in: PubMed
    19. Garcia-Carbonero R, Capdevila J, Crespo-Herrero G, Díaz-Pérez JA, Martínez Del Prado MP, Alonso Orduña V, Sevilla-García I, Villabona-Artero C, Beguiristain-Gómez A, Llanos-Muñoz M, Marazuela M, Alvarez-Escola C, Castellano D, Vilar E, Jiménez-Fonseca P, Teulé A, Sastre-Valera J, Benavent-Viñuelas M, Monleon A, Salazar R. Incidence, patterns of care and prognostic factors for outcome of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): results from the National Cancer Registry of Spain (RGETNE). Ann Oncol. 2010 Sep; 21(9):1794-803. PMID: 20139156.
      View in: PubMed
    20. Vilar E, Mukherjee B, Kuick R, Raskin L, Misek DE, Taylor JM, Giordano TJ, Hanash SM, Fearon ER, Rennert G, Gruber SB. Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. Clin Cancer Res. 2009 Apr 15; 15(8):2829-39. PMID: 19351759.
      View in: PubMed
    21. Vilar E, Scaltriti M, Balmaña J, Saura C, Guzman M, Arribas J, Baselga J, Tabernero J. Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. Br J Cancer. 2008 Nov 18; 99(10):1607-12. PMID: 18941461.
      View in: PubMed
    22. Vilar E, Salazar R, Pérez-García J, Cortes J, Oberg K, Tabernero J. Chemotherapy and role of the proliferation marker Ki-67 in digestive neuroendocrine tumors. Endocr Relat Cancer. 2007 Jun; 14(2):221-32. PMID: 17639039.
      View in: PubMed
    23. Durán I, Salazar R, Casanovas O, Arrazubi V, Vilar E, Siu LL, Yao J, Tabernero J. New drug development in digestive neuroendocrine tumors. Ann Oncol. 2007 Aug; 18(8):1307-13. PMID: 17301070.
      View in: PubMed
    24. del Campo JM, Vilar E. [New challenges for molecular oncology in ovarian carcinoma]. Med Clin (Barc). 2007 Jan 13; 128(1):15-7. PMID: 17266887.
      View in: PubMed
    25. Vilar E, Calvo E, Tabernero J. Molecular biology of testicular germ cell tumors. Clin Transl Oncol. 2006 Dec; 8(12):846-50. PMID: 17169757.
      View in: PubMed
    26. Felip E, Vilar E. The expanding role of systemic treatment in non-small cell lung cancer neo-adjuvant therapy. Ann Oncol. 2006 Sep; 17 Suppl 10:x108-12. PMID: 17018710.
      View in: PubMed
    27. Vilar E, Balmaña J, Espín E. BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors. Cancer. 2006 Jun 01; 106(11):2528-9; author reply 2529. PMID: 16628650.
      View in: PubMed
    28. Vilar E, Tabernero J, Casado E, Macarulla T, Ramos FJ, Martinelli E, Saura C. Lack of efficacy of streptozocin and doxorubicin in patients with advanced pancreatic endocrine tumors. Am J Clin Oncol. 2005 Aug; 28(4):424. PMID: 16062087.
      View in: PubMed
    29. Identification of a novel PMS2 alteration c.505C>G (R169G) in trans with a PMS2 pathogenic mutation in a patient with constitutional mismatch repair deficiency. Familial Cancer. 1-5.
    30. Oncogenic targets Mmp7, S100a9, Nppb and Aldh1a3 from transcriptome profiling of FAP and Pirc adenomas are downregulated in response to tumor suppression by Clotam. International Journal of Cancer.
    31. Reply to L.B. Saltz. Journal of Clinical Oncology. 34:1560.
    32. DNA Mismatch Repair Deficiency in Rectal Cancer. Journal of Clinical Oncology. 34:3039-3046.
    33. Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials. Annals of Oncology. 27:1068-1074.
    34. Patient-reported disease knowledge and educational needs in Lynch syndrome. Hereditary Cancer in Clinical Practice. 12.
    35. Embarazo ectopico. Ciencia Ginecologika. 3:241-246.
    36. Leveraging premalignant biology for immune-based cancer prevention. Proceedings of the National Academy of Sciences of the United States of America. 113:10750-10758.
    37. Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment. Annals of Oncology. 26:731-736.
    38. Perspectivas actuales del diagnóstico prenatal. Ciencia Ginecologika. 5:137-138.
    39. Fibrosis quística y contracepción. Toko-Ginecologia Practica. 60:24-29.
    40. Familial Cancer. 1-5.
    41. Genomic landscape of colorectal mucosa and adenomas. Cancer Prevention Research. 9:417-427.
    42. High prevalence of hereditary cancer syndromes in adolescents and young adults with colorectal cancer. Journal of Clinical Oncology. 33:3544-3549.
    43. Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq. Bioinformatics. 32:3015-3017.
    44. Molecular markers in colorectal cancer. Colorectal Cancer. 2:243-263.
    45. MUTYH-associated polyposis. 25-32.
    46. Spontaneous hematoma of the abdominal wall in pregnancy. Journal of Gynecologic Surgery. 18:105-107.
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