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ANDREW GLADDEN

TitleAssistant Professor
InstitutionMD Anderson
DepartmentGenetics
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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lopez EW, Vue Z, Broaddus RR, Behringer RR, Gladden AB. The ERM family member Merlin is required for endometrial gland morphogenesis. Dev Biol. 2018 10 15; 442(2):301-314. PMID: 30118662.
      View in: PubMed
    2. Williams E, Villar-Prados A, Bowser J, Broaddus R, Gladden AB. Loss of polarity alters proliferation and differentiation in low-grade endometrial cancers by disrupting Notch signaling. PLoS One. 2017; 12(12):e0189081. PMID: 29206870.
      View in: PubMed
    3. Yang CC, Graves HK, Moya IM, Tao C, Hamaratoglu F, Gladden AB, Halder G. Differential regulation of the Hippo pathway by adherens junctions and apical-basal cell polarity modules. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):1785-90. PMID: 25624491.
      View in: PubMed
    4. Hebert AM, DuBoff B, Casaletto JB, Gladden AB, McClatchey AI. Merlin/ERM proteins establish cortical asymmetry and centrosome position. Genes Dev. 2012 Dec 15; 26(24):2709-23. PMID: 23249734.
      View in: PubMed
    5. Longworth MS, Walker JA, Anderssen E, Moon NS, Gladden A, Heck MM, Ramaswamy S, Dyson NJ. A shared role for RBF1 and dCAP-D3 in the regulation of transcription with consequences for innate immunity. PLoS Genet. 2012; 8(4):e1002618. PMID: 22496667.
      View in: PubMed
    6. Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010 Nov 16; 19(5):727-39. PMID: 21074722.
      View in: PubMed
    7. Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes Dev. 2010 Aug 15; 24(16):1718-30. PMID: 20675406.
      View in: PubMed
    8. Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, Goradia A, Wasik MA, Klein-Szanto AJ, Rustgi AK, Bassing CH, Diehl JA. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev. 2007 Nov 15; 21(22):2908-22. PMID: 18006686.
      View in: PubMed
    9. Lin DI, Lessie MD, Gladden AB, Bassing CH, Wagner KU, Diehl JA. Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis. Oncogene. 2008 Feb 21; 27(9):1231-42. PMID: 17724472.
      View in: PubMed
    10. Marzec M, Kasprzycka M, Lai R, Gladden AB, Wlodarski P, Tomczak E, Nowell P, Deprimo SE, Sadis S, Eck S, Schuster SJ, Diehl JA, Wasik MA. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity. Blood. 2006 Sep 01; 108(5):1744-50. PMID: 16690963.
      View in: PubMed
    11. Gladden AB, Woolery R, Aggarwal P, Wasik MA, Diehl JA. Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma. Oncogene. 2006 Feb 16; 25(7):998-1007. PMID: 16247460.
      View in: PubMed
    12. Gladden AB, Diehl JA. Location, location, location: the role of cyclin D1 nuclear localization in cancer. J Cell Biochem. 2005 Dec 01; 96(5):906-13. PMID: 16163738.
      View in: PubMed
    13. Petre-Draviam CE, Williams EB, Burd CJ, Gladden A, Moghadam H, Meller J, Diehl JA, Knudsen KE. A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene. 2005 Jan 13; 24(3):431-44. PMID: 15558026.
      View in: PubMed
    14. Lu F, Gladden AB, Diehl JA. An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene. Cancer Res. 2003 Nov 01; 63(21):7056-61. PMID: 14612495.
      View in: PubMed
    15. Gladden AB, Diehl JA. Cell cycle progression without cyclin E/CDK2: breaking down the walls of dogma. Cancer Cell. 2003 Sep; 4(3):160-2. PMID: 14522248.
      View in: PubMed
    16. Gladden AB, Diehl JA. The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding. J Biol Chem. 2003 Mar 14; 278(11):9754-60. PMID: 12519773.
      View in: PubMed
    17. Alt JR, Gladden AB, Diehl JA. p21(Cip1) Promotes cyclin D1 nuclear accumulation via direct inhibition of nuclear export. J Biol Chem. 2002 Mar 08; 277(10):8517-23. PMID: 11751903.
      View in: PubMed
    18. P09-20 LB. Ultra-deep sequencing of full-length HIV-1 genomes identifies rapid viral evolution during acute infection. Retrovirology. 6.
    19. Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer. Oncogene.
    20. Differential regulation of the Hippo pathway by adherens junctions and apical- Basal cell polarity modules. Proceedings of the National Academy of Sciences of the United States of America. 112:1785-1790.
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