KEN HE YOUNG

TitleProfessor
InstitutionMD Anderson
DepartmentHematopathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xu-Monette ZY, Li Y, Snyder T, Yu T, Lu T, Tzankov A, Visco C, Bhagat G, Qian W, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Wang Y, Go H, Ponzoni M, Ferreri AJM, M?ller MB, Parsons BM, Fan X, van Krieken JH, Piris MA, Winter JN, Au Q, Kirsch I, Zhang M, Shaughnessy J, Xu B, Young KH. Tumor-Infiltrating Normal B Cells Revealed by Immunoglobulin Repertoire Clonotype Analysis Are Highly Prognostic and Crucial for Antitumor Immune Responses in DLBCL. Clin Cancer Res. 2023 12 01; 29(23):4808-4821. PMID: 37728879; PMCID: PMC10842978.
      Citations: 2     Fields:    Translation:HumansCells
    2. Wessel J, Heard-Costa N, Mahaney MC, Montasser ME, Terry JG, Yanek LR, Bon J, Duggirala R, Jacobs DR, Kalyani RR, Lange LA, Mitchell BD, Smith JA, Curran JE, Kardia SLR, Kral BG, Momin Z, Newman AB, Post WS, Viaud-Martinez KA, Becker LC, Blangero J, Pratte K, Rich SS, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Atherosclerosis Working Group; , Wu JC, Peyser PA, Rotter JI, Hasbani NR, Westerman KE, Kwak SH, Chen H, Li X, Di Corpo D, Bis JC, Sarnowski C, Wu P, Bielak LF, Guo X, Kinney GL, Palmer ND, Raffield LM, Bowden DW, Brody JA, Taylor KD, Carson AP, Fornage M, Freedman BI, Gabriel S, Gibbs RA, Gupta N, Young KA, Bertoni AG, Carr JJ, Psaty BM, Malhotra R, Morrison AC, Vasan RS, Lin X, Meigs JB, Manning AK, de Vries PS. Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis. Circ Genom Precis Med. 2023 Dec; 16(6):e004176. PMID: 38014529; PMCID: PMC10843644.
      Citations:    Fields:    Translation:Humans
    3. Castaldi PJ, Xu Z, Young KA, Hokanson JE, Lynch DA, Humphries SM, Ross JC, Cho MH, Hersh CP, Crapo JD, Strand M, Silverman EK. Heterogeneity and Progression of Chronic Obstructive Pulmonary Disease: Emphysema-Predominant and Non-Emphysema-Predominant Disease. Am J Epidemiol. 2023 10 10; 192(10):1647-1658. PMID: 37160347.
      Citations:    Fields:    
    4. Diaz AA, Wang W, Orejas JL, Elalami R, Dolliver WR, Nardelli P, San Jos? Est?par R, Choi B, Pistenmaa CL, Ross JC, Maselli DJ, Yen A, Young KA, Kinney GL, Cho MH, San Jos? Est?par R. Suspected Bronchiectasis and Mortality in Adults With a History of Smoking Who Have Normal and Impaired Lung Function : A Cohort Study. Ann Intern Med. 2023 10; 176(10):1340-1348. PMID: 37782931; PMCID: PMC10809158.
      Citations:    Fields:    Translation:Humans
    5. Sircar A, Singh S, Xu-Monette ZY, Coyle KM, Hilton LK, Chavdoula E, Ranganathan P, Jain N, Hanel W, Tsichlis P, Alinari L, Peterson BR, Tao J, Muthusamy N, Baiocchi R, Epperla N, Young KH, Morin R, Sehgal L. Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma. Leukemia. 2023 10; 37(10):2094-2106. PMID: 37598282; PMCID: PMC10539170.
      Citations:    Fields:    Translation:HumansCells
    6. Chung EYL, Sartori G, Ponzoni M, Cascione L, Priebe V, Xu-Monette ZY, Fang X, Zhang M, Visco C, Tzankov A, Rinaldi A, Sgrignani J, Zucca E, Rossi D, Cavalli A, Inghirami G, Scott DW, Young KH, Bertoni F. ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells. Br J Haematol. 2023 Oct; 203(2):244-254. PMID: 37584198.
      Citations:    Fields:    
    7. Lu T, Zhang J, Xu-Monette ZY, Young KH. The progress of novel strategies on immune-based therapy in relapsed or refractory diffuse large B-cell lymphoma. Exp Hematol Oncol. 2023 Aug 14; 12(1):72. PMID: 37580826; PMCID: PMC10424456.
      Citations: 2     
    8. Zhou S, Fan C, Zeng Z, Young KH, Li Y. Corrigendum: Clinical and immunological effects of p53-targeting vaccines. Front Cell Dev Biol. 2023; 11:1267661. PMID: 37601114; PMCID: PMC10436199.
      Citations:    
    9. Zhou S, Chai D, Wang X, Neeli P, Yu X, Davtyan A, Young K, Li Y. AI-powered discovery of a novel p53-Y220C reactivator. Front Oncol. 2023; 13:1229696. PMID: 37593097; PMCID: PMC10430779.
      Citations: 1     
    10. Wan X, Young KH, Bai O. HBV-associated DLBCL of poor prognosis: advance in pathogenesis, immunity and therapy. Front Immunol. 2023; 14:1216610. PMID: 37483605; PMCID: PMC10360167.
      Citations: 1     Fields:    Translation:HumansCells
    11. Khanlari M, Mo H, Kim DH, Sakhdari A, Young KH, Jain P, Wang M, Li S, Kanagal-Shamanna R, Miranda RN, Vega F, Medeiros LJ, Ok CY. Blastoid and Pleomorphic Mantle Cell Lymphoma Demonstrate Distinct Clinicopathologic and Genetic Features. Am J Surg Pathol. 2023 08 01; 47(8):849-858. PMID: 37288826; PMCID: PMC10348620.
      Citations:    Fields:    Translation:HumansCells
    12. Kurniansyah N, Goodman MO, Khan AT, Wang J, Feofanova E, Bis JC, Wiggins KL, Huffman JE, Kelly T, Elfassy T, Guo X, Palmas W, Lin HJ, Hwang SJ, Gao Y, Young K, Kinney GL, Smith JA, Yu B, Liu S, Wassertheil-Smoller S, Manson JE, Zhu X, Chen YI, Lee IT, Gu CC, Lloyd-Jones DM, Z?llner S, Fornage M, Kooperberg C, Correa A, Psaty BM, Arnett DK, Isasi CR, Rich SS, Kaplan RC, Redline S, Mitchell BD, Franceschini N, Levy D, Rotter JI, Morrison AC, Sofer T. Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups. Nat Commun. 2023 06 02; 14(1):3202. PMID: 37268629; PMCID: PMC10238525.
      Citations:    Fields:    Translation:Humans
    13. Al-Juhaishi T, Wang Y, Milton DR, Xu-Monette ZY, Jabbour E, Daher M, Im JS, Bashir Q, Iyer SP, Marin D, Olson AL, Popat U, Qazilbash M, Rondon G, Gulbis AM, Champlin RE, Young KH, Khouri IF. Clinical relevance of MYC/BCL2 expression and cell of origin in patients with diffuse large b-cell lymphoma treated with autologous transplant. Bone Marrow Transplant. 2023 09; 58(9):1000-1007. PMID: 37198234.
      Citations:    Fields:    Translation:Humans
    14. Li Y, Xu-Monette ZY, Abramson J, Sohani AR, Bhagat G, Tzankov A, Visco C, Zhang S, Dybkaer K, Pan Z, Xu M, Tam W, Zu Y, Hsi ED, Hagemeister FB, Go H, van Krieken JH, Winter JN, Ponzoni M, Ferreri AJM, M?ller MB, Piris MA, Wang Y, Zhang M, Young KH. EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential. Blood Adv. 2023 04 11; 7(7):1308-1311. PMID: 36399513; PMCID: PMC10119604.
      Citations: 1     Fields:    Translation:Cells
    15. Pang Y, Lu T, Xu-Monette ZY, Young KH. Metabolic Reprogramming and Potential Therapeutic Targets in Lymphoma. Int J Mol Sci. 2023 Mar 13; 24(6). PMID: 36982568; PMCID: PMC10052731.
      Citations: 2     Fields:    Translation:HumansCells
    16. Yu X, Li W, Liu H, Wang X, Coarfa C, Cheng C, Yu X, Zeng Z, Cao Y, Young KH, Li Y. PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination. J Clin Invest. 2023 02 01; 133(3). PMID: 36719382; PMCID: PMC9888393.
      Citations:    Fields:    Translation:AnimalsCells
    17. Wang X, Young KH, Zhang M. Should DDGP Regimen Be the Standard of Care for Advanced Extranodal NK/T-Cell Lymphoma? The New Staging System Matters-Reply. JAMA Oncol. 2023 02 01; 9(2):279-280. PMID: 36480197.
      Citations:    Fields:    Translation:Humans
    18. D?az AA, Nardelli P, Wang W, San Jos? Est?par R, Yen A, Kligerman S, Maselli DJ, Dolliver WR, Tsao A, Orejas JL, Aliberti S, Aksamit TR, Young KA, Kinney GL, Washko GR, San Jos? Est?par R, Silverman EK. Artificial Intelligence-based CT Assessment of Bronchiectasis: The COPDGene Study. Radiology. 2023 04; 307(1):e221109. PMID: 36511808; PMCID: PMC10068886.
      Citations: 1     Fields:    Translation:Humans
    19. Yu F, He H, Nastoupil LJ, Xu-Monette ZY, Pham K, Liang Y, Chen G, Fowler NH, Yin CC, Tan D, Yang Y, Hu S, Young KH, Pham LV, You MJ. Targetable vulnerability of deregulated FOXM1/PLK1 signaling axis in diffuse large B cell lymphoma. Am J Cancer Res. 2022; 12(10):4666-4679. PMID: 36381323; PMCID: PMC9641390.
      Citations: 1     
    20. Liu W, Cai Q, Yu T, Strati P, Hagemeister FB, Zhai Q, Zhang M, Li L, Fang X, Li J, Sun R, Zhang S, Yang H, Wang Z, Qian W, Iwaki N, Sato Y, Oksenhendler E, Xu-Monette ZY, Young KH, Yu L. Clinical characteristics and outcomes of Castleman disease: a multicenter Consortium study of 428 patients with 15-year follow-up. Am J Cancer Res. 2022; 12(9):4227-4240. PMID: 36225639; PMCID: PMC9548017.
      Citations: 1     
    21. Yu T, Cai QQ, Zhai QL, Li L, Fang X, Li J, Sun R, Yang H, Wang Z, Qian W, Xu-Monette ZY, Young KH, Yu L. Analysis of albumin as a prognostic factor in HHV-8/HIV-negative Castleman disease from a multicenter study. Leuk Lymphoma. 2022 Sep 07; 1-10. PMID: 36074798.
      Citations:    
    22. Sang W, Ma Y, Wang X, Ma Y, Shen Z, Gu W, Wang F, Ye J, Zhang C, Miao Y, Xu C, Liu Q, Li B, Tu J, Wang C, Shi Y, Sun S, Yan D, Song X, Sun C, Shao Y, Xu L, Li Z, Ma D, Xu K, Young KH, Liu H. Clinicopathologic Features and Genomic Signature of De Novo CD5 + Diffuse Large B-Cell Lymphoma : A Multicenter Collaborative Study. Am J Surg Pathol. 2022 Nov 01; 46(11):1533-1544. PMID: 36006771.
      Citations:    
    23. Liu L, Yu X, Li Z, He X, Zha J, Lin Z, Hong Y, Zheng H, Lai Q, Ding K, Jia X, Fu G, Yu H, Yang H, Li Z, Young KH, Xu B. Revealing the evolution of the tumor immune microenvironment in follicular lymphoma patients progressing within 24 months using single-cell imaging mass cytometry. J Hematol Oncol. 2022 08 22; 15(1):115. PMID: 35996180; PMCID: PMC9396877.
      Citations:    
    24. Wan X, Guo W, Wang X, Li J, Zhao Y, Feng X, Young KH, Bai O. Improving the prognostic ability of PET/CT SUVmax to identify follicular lymphoma with early treatment failure. Am J Cancer Res. 2022; 12(8):3857-3869. PMID: 36119824; PMCID: PMC9442020.
      Citations:    
    25. Luo C, Yu T, Young KH, Yu L. HDAC inhibitor chidamide synergizes with venetoclax to inhibit the growth of diffuse large B-cell lymphoma via down-regulation of MYC, BCL2, and TP53 expression. J Zhejiang Univ Sci B. 2022 Aug 15; 23(8):666-681. PMID: 35953760; PMCID: PMC9381329.
      Citations:    
    26. Wang X, Zhang L, Liu X, Li X, Li L, Fu X, Sun Z, Wu J, Zhang X, Yan J, Chang Y, Nan F, Zhou Z, Wu X, Tian L, Ma M, Li Z, Yu H, Zhu L, Wang Y, Shi C, Feng X, Li J, Ding M, Zhang J, Dong M, Xue H, Wang J, Zou L, Su L, Wu J, Liu L, Bao H, Zhang L, Guo Y, Guo S, Lu Y, Young KH, Li W, Zhang M. Efficacy and Safety of a Pegasparaginase-Based Chemotherapy Regimen vs an L-asparaginase-Based Chemotherapy Regimen for Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized Clinical Trial. JAMA Oncol. 2022 07 01; 8(7):1035-1041. PMID: 35708709; PMCID: PMC9204617.
      Citations:    
    27. Wang X, Yu X, Li W, Neeli P, Liu M, Li L, Zhang M, Fang X, Young KH, Li Y. Expanding anti-CD38 immunotherapy for lymphoid malignancies. J Exp Clin Cancer Res. 2022 Jun 28; 41(1):210. PMID: 35765110; PMCID: PMC9237984.
      Citations:    Fields:    Translation:HumansAnimals
    28. Zhang S, Gu C, Huang L, Wu H, Shi J, Zhang Z, Zhou Y, Zhou J, Gao Y, Liu J, Leng Y, Liu X, Zhang Q, Huang L, Tong X, Young KH, Li J, Zhu H, Zhang T. The third-generation anti-CD30 CAR T-cells specifically homing to the tumor and mediating powerful antitumor activity. Sci Rep. 2022 06 21; 12(1):10488. PMID: 35729339; PMCID: PMC9213494.
      Citations:    
    29. Munroe ME, Young KA, Guthridge JM, Kamen DL, Gilkeson GS, Weisman MH, Ishimori ML, Wallace DJ, Karp DR, Harley JB, Norris JM, James JA. Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals. Front Immunol. 2022; 13:866181. PMID: 35720322; PMCID: PMC9203691.
      Citations:    Fields:    Translation:Humans
    30. Vanderlinden LA, Bemis EA, Seifert J, Guthridge JM, Young KA, Demoruelle MK, Feser M, DeJager W, Macwana S, Mikuls TR, O'Dell JR, Weisman MH, Buckner J, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Deane KD, James JA, Holers VM, Norris JM. Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus. Front Immunol. 2022; 13:881332. PMID: 35720397; PMCID: PMC9205604.
      Citations:    Fields:    Translation:Humans
    31. Gisriel SD, Yuan J, Braunberger RC, Maracaja DLV, Chen X, Wu X, McCracken J, Chen M, Xie Y, Brown LE, Li P, Zhou Y, Sethi T, McHenry A, Hauser RG, Paulson N, Tang H, Hsi ED, Wang E, Zhang QY, Young KH, Xu ML, Pan Z. Human herpesvirus 8-negative effusion-based large B-cell lymphoma: a distinct entity with unique clinicopathologic characteristics. Mod Pathol. 2022 10; 35(10):1411-1422. PMID: 35562413; PMCID: PMC9926946.
      Citations:    
    32. Elfrink S, Ter Beest M, Janssen L, Baltissen MP, Jansen PWTC, Kenyon AN, Steen RM, de Windt D, Hagemann PM, Hess C, van Spronsen DJ, Hoevenaars B, van der Spek E, Xu-Monette ZY, Young KH, Kaffa C, Bervoets S, van Heek J, Hesius E, de Winde CM, Vermeulen M, van den Brand M, Scheijen B, van Spriel AB. IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma. Blood Adv. 2022 04 12; 6(7):2254-2266. PMID: 35086136; PMCID: PMC9006271.
      Citations:    Fields:    Translation:HumansCells
    33. Xu-Monette ZY, Wei L, Fang X, Au Q, Nunns H, Tzankov A, Zhu F, Visco C, Bhagat G, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Sun X, Han X, Go H, Ponzoni M, Parsons BM, van Krieken JH, Winter JN, Li Y, Xu B, Albitar M, You H, Young KH, Nagy M, Ferreri AJM, M?ller MB, Piris MA. Genetic Subtyping and Phenotypic Characterization of the Immune Microenvironment and MYC/BCL2 Double Expression Reveal Heterogeneity in Diffuse Large B-cell Lymphoma. Clin Cancer Res. 2022 Mar 01; 28(5):972-983. PMID: 34980601; PMCID: PMC9137388.
      Citations: 1     Fields:    Translation:Humans
    34. Pandey PR, Young KH, Kumar D, Jain N. RNA-mediated immunotherapy regulating tumor immune microenvironment: next wave of cancer therapeutics. Mol Cancer. 2022 02 21; 21(1):58. PMID: 35189921; PMCID: PMC8860277.
      Citations: 4     Fields:    Translation:Humans
    35. Albitar M, Zhang H, Goy A, Xu-Monette ZY, Bhagat G, Visco C, Tzankov A, Fang X, Zhu F, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Huh J, Ponzoni M, Parsons BM, van Krieken JH, Winter JN, Li Y, Xu B, Young KH, Ferreri AJM, M?ller MB, Piris MA. Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms. Blood Cancer J. 2022 02 01; 12(2):25. PMID: 35105854; PMCID: PMC8807629.
      Citations: 1     Fields:    Translation:HumansCells
    36. Liu H, Xu-Monette ZY, Tang G, Wang W, Kim Y, Yuan J, Li Y, Chen W, Li Y, Fedoriw GY, Zhu F, Fang X, Luedke C, Medeiros LJ, Young KH, Hu S. EBV+ high-grade B cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a multi-institutional study. Histopathology. 2022 Feb; 80(3):575-588. PMID: 34637146.
      Citations:    Fields:    Translation:HumansCells
    37. Zhang W, Ao Q, Guan Y, Zhu Z, Kuang D, Li MMQ, Shen K, Zhang M, Wang J, Yang L, Cai H, Wang Y, Young KH, Zhou J, Xiao M. A novel diagnostic approach for the classification of small B-cell lymphoid neoplasms based on the NanoString platform. Mod Pathol. 2022 05; 35(5):632-639. PMID: 34802044; PMCID: PMC9042706.
      Citations:    
    38. Feng X, Guo W, Wang Y, Li J, Zhao Y, Qu L, Yan X, Li J, Guo Q, Young KH, Bai O. The Short-Term Efficacy and Safety of Brentuximab Vedotin Plus Cyclophosphamide, Epirubicin and Prednisone in Untreated PTCL: A Real-World, Retrospective Study. Adv Ther. 2022 01; 39(1):532-543. PMID: 34797505; PMCID: PMC8799538.
      Citations:    
    39. Yu X, Li W, Young KH, Li Y. Posttranslational Modifications in PD-L1 Turnover and Function: From Cradle to Grave. Biomedicines. 2021 Nov 16; 9(11). PMID: 34829931; PMCID: PMC8615371.
      Citations:    
    40. Mason SE, Moreta-Martinez R, Labaki WW, Strand MJ, Regan EA, Bon J, San Jose Estepar R, Casaburi R, McDonald ML, Rossiter HB, Make B, Dransfield MT, Han MK, Young K, Curtis JL, Stringer K, Kinney G, Hokanson JE, San Jose Estepar R, Washko GR, COPDGene Investigators. Longitudinal Association Between Muscle Loss and Mortality in Ever Smokers. Chest. 2022 04; 161(4):960-970. PMID: 34785234; PMCID: PMC9005860.
      Citations:    
    41. Zhou S, Fan C, Zeng Z, Young KH, Li Y. Clinical and Immunological Effects of p53-Targeting Vaccines. Front Cell Dev Biol. 2021; 9:762796. PMID: 34805170; PMCID: PMC8595300.
      Citations:    
    42. Youssef Y, Karkhanis V, Chan WK, Jeney F, Canella A, Zhang X, Sloan S, Prouty A, Helmig-Mason J, Tsyba L, Hanel W, Zheng X, Zhang P, Chung JH, Lucas DM, Kauffman Z, Larkin K, Strohecker AM, Ozer HG, Lapalombella R, Zhou H, Xu-Monette ZY, Young KH, Han R, Nurmemmedov E, Nuovo G, Maddocks K, Byrd JC, Baiocchi RA, Alinari L. Transducin ?-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma. Haematologica. 2021 11 01; 106(11):2927-2939. PMID: 33054136; PMCID: PMC8561281.
      Citations: 2     Fields:    Translation:Humans
    43. Wan ES, Hokanson JE, Regan EA, Young KA, Make BJ, DeMeo DL, Mason SE, San Jose Estepar R, Crapo JD, Silverman EK. Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers. Chest. 2022 03; 161(3):651-661. PMID: 34592319; PMCID: PMC8941606.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    44. Tian XP, Ma SY, Young KH, Ong CK, Liu YH, Li ZH, Zhai QL, Huang HQ, Lin TY, Li ZM, Xia ZJ, Zhong LY, Rao HL, Li M, Cai J, Zhang YC, Zhang F, Su N, Li PF, Zhu F, Xu-Monette ZY, Wong EKY, Ha JCH, Khoo LP, Ai L, Cheng RF, Lim JQ, de Mel S, Ng SB, Lim ST, Cai QQ. A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma. Blood. 2021 08 12; 138(6):452-463. PMID: 33728448.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    45. Martinez-Baquero D, Sakhdari A, Mo H, Kim DH, Kanagal-Shamanna R, Li S, Young KH, O'Malley DP, Dogan A, Jain P, Wang ML, McDonnell TJ, Miranda RN, Vega F, Medeiros LJ, Ok CY. EZH2 expression is associated with inferior overall survival in mantle cell lymphoma. Mod Pathol. 2021 12; 34(12):2183-2191. PMID: 34376807; PMCID: PMC10563799.
      Citations:    Fields:    Translation:HumansCells
    46. Lei W, Xie M, Jiang Q, Xu N, Li P, Liang A, Young KH, Qian W. Treatment-Related Adverse Events of Chimeric Antigen Receptor T-Cell (CAR T) in Clinical Trials: A Systematic Review and Meta-Analysis. Cancers (Basel). 2021 Aug 03; 13(15). PMID: 34359816; PMCID: PMC8345443.
      Citations:    
    47. You H, Xu-Monette ZY, Wei L, Nunns H, Bhagat G, Fang X, Zhu F, Visco C, Tzankov A, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Huh J, Ponzoni M, Parsons BM, Van Krieken JH, Piris MA, Li Y, Au Q, Xu B, Albitar M, Young KH, Nagy ML, Ferreri AJM, M?ller MB, Winter JN. Genomic complexity is associated with epigenetic regulator mutations and poor prognosis in diffuse large B-cell lymphoma. Oncoimmunology. 2021; 10(1):1928365. PMID: 34350060; PMCID: PMC8293967.
      Citations: 3     Fields:    Translation:Humans
    48. Burnside ES, Warren LM, Myles J, Wilkinson LS, Wallis MG, Patel M, Smith RA, Young KC, Massat NJ, Duffy SW. Quantitative breast density analysis to predict interval and node-positive cancers in pursuit of improved screening protocols: a case-control study. Br J Cancer. 2021 09; 125(6):884-892. PMID: 34168297; PMCID: PMC8438060.
      Citations: 3     Fields:    Translation:Humans
    49. Yu X, Li W, Deng Q, Liu H, Wang X, Hu H, Cao Y, Xu-Monette ZY, Li L, Zhang M, Lu Z, Young KH, Li Y. MYD88 L265P elicits mutation-specific ubiquitination to drive NF-?B activation and lymphomagenesis. Blood. 2021 03 25; 137(12):1615-1627. PMID: 33025009; PMCID: PMC7995293.
      Citations: 7     Fields:    Translation:HumansCells
    50. Wang Y, Gali VL, Xu-Monette ZY, Sano D, Thomas SK, Weber DM, Zhu F, Fang X, Deng M, Zhang M, Hagemeister FB, Li Y, Orlowski RZ, Lee HC, Young KH. Molecular and genetic biomarkers implemented from next-generation sequencing provide treatment insights in clinical practice for Waldenstr?m macroglobulinemia. Neoplasia. 2021 04; 23(4):361-374. PMID: 33735664; PMCID: PMC7985670.
      Citations: 2     Fields:    Translation:Humans
    51. Yuan D, Li G, Yu L, Jiang Y, Shi Y, Chen Q, Ma X, Pham LV, Young KH, Deng M, Fang Z, Xu B. CS2164 and Venetoclax Show Synergistic Antitumoral Activities in High Grade B-Cell Lymphomas With MYC and BCL2 Rearrangements. Front Oncol. 2021; 11:618908. PMID: 33777762; PMCID: PMC7988232.
      Citations: 1     
    52. Fang X, Young KH. Hepatitis B virus antibody status provides new insights in diffuse large B-Cell lymphoma. Leuk Lymphoma. 2021 06; 62(6):1281-1283. PMID: 33648420.
      Citations:    
    53. Young KH. Intensive chemotherapy and sequential hematopoietic stem cell transplantation: Is it necessary for high-risk T-cell lymphoblastic lymphoma? Cancer Commun (Lond). 2021 03; 41(3):273-274. PMID: 33605562; PMCID: PMC7968878.
      Citations:    
    54. Liang Y, Liu H, Lu Z, Lei W, Zhang C, Li P, Liang A, Young KH, Qian W. CD19 CAR-T expressing PD-1/CD28 chimeric switch receptor as a salvage therapy for DLBCL patients treated with different CD19-directed CAR T-cell therapies. J Hematol Oncol. 2021 02 16; 14(1):26. PMID: 33593414; PMCID: PMC7885572.
      Citations:    
    55. Mason SE, Moreta-Martinez R, Labaki WW, Strand M, Baraghoshi D, Regan EA, Bon J, San Jose Estepar R, Casaburi R, McDonald MN, Rossiter H, Make BJ, Dransfield MT, Han MK, Young KA, Kinney G, Hokanson JE, San Jose Estepar R, Washko GR, COPDGene Investigators, COPDGene? Investigators. Respiratory exacerbations are associated with muscle loss in current and former smokers. Thorax. 2021 06; 76(6):554-560. PMID: 33574123; PMCID: PMC8222105.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    56. R Arnold N, S Wan E, Hersh CP, Schwartz A, Kinney G, Young K, Hokanson J, Regan EA, P Comellas A, Fortis S. Inhaled Medication Use in Smokers With Normal Spirometry. Respir Care. 2021 Apr; 66(4):652-660. PMID: 33563793; PMCID: PMC9993991.
      Citations:    Fields:    Translation:Humans
    57. Wang L, Li LR, Young KH. New agents and regimens for diffuse large B cell lymphoma. J Hematol Oncol. 2020 12 14; 13(1):175. PMID: 33317571; PMCID: PMC7734862.
      Citations:    
    58. Fang X, Sun Z, Xu-Monette ZY, Young KH. Predictive Model for Idiopathic Multicentric Castleman Disease Supporting Treatment Decisions. Oncologist. 2021 01; 26(1):4-6. PMID: 33215784; PMCID: PMC7794201.
      Citations:    Fields:    Translation:Humans
    59. Deng M, Xu-Monette ZY, Pham LV, Wang X, Tzankov A, Fang X, Zhu F, Visco C, Bhagat G, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, You H, Huh J, Ponzoni M, Parsons BM, Hagemeister F, van Krieken JH, Winter JN, Li Y, Xu B, Liu P, Young KH, Ferreri AJM, M?ller MB, Piris MA. Aggressive B-cell Lymphoma with MYC/TP53 Dual Alterations Displays Distinct Clinicopathobiological Features and Response to Novel Targeted Agents. Mol Cancer Res. 2021 02; 19(2):249-260. PMID: 33154093; PMCID: PMC8092941.
      Citations: 5     Fields:    Translation:HumansCells
    60. Deng M, Zhang M, Xu-Monette ZY, Pham LV, Tzankov A, Visco C, Fang X, Bhagat G, Zhu F, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Choi WWL, Huh J, Ponzoni M, Parsons BM, van Krieken JH, Winter JN, Hagemeister F, Alinari L, Li Y, Andreeff M, Xu B, Young KH, Ferreri AJM, M?ller MB, Piris MA. XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53. J Hematol Oncol. 2020 11 04; 13(1):148. PMID: 33148342; PMCID: PMC7641823.
      Citations: 10     Fields:    Translation:HumansCells
    61. Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB, Nothnagel M, Drichel D, Winterer G. Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. Nat Commun. 2020 11 03; 11(1):5562. PMID: 33144568; PMCID: PMC7642344.
      Citations: 20     Fields:    Translation:Humans
    62. Liu H, Lei W, Zhang C, Yang C, Wei J, Guo Q, Guo X, Chen Z, Lu Y, Young KH, Lu Z, Qian W. CD19-specific CAR T Cells that Express a PD-1/CD28 Chimeric Switch-Receptor are Effective in Patients with PD-L1-positive B-Cell Lymphoma. Clin Cancer Res. 2021 01 15; 27(2):473-484. PMID: 33028589.
      Citations:    
    63. Lyapichev KA, Sakhdari A, Khoury JD, O'Malley DP, El Hussein S, Yin CC, Patel KP, Thakral B, Young KH, Medeiros LJ, Konoplev S. Lymphoid enhancer binding factor 1 (LEF1) expression is significantly higher in Hodgkin lymphoma associated with Richter syndrome relative to de novo classic Hodgkin lymphoma. Ann Diagn Pathol. 2020 Dec; 49:151636. PMID: 32977233.
      Citations:    Fields:    Translation:Humans
    64. Yu L, Shi M, Cai Q, Strati P, Hagemeister F, Zhai Q, Li L, Fang X, Li J, Sun R, Zhang S, Yang H, Wang Z, Qian W, Iwaki N, Sato Y, Zhang L, Li J, Xu-Monette ZY, Young KH, Oksenhendler E. A Novel Predictive Model for Idiopathic Multicentric Castleman Disease: The International Castleman Disease Consortium Study. Oncologist. 2020 11; 25(11):963-973. PMID: 32852137; PMCID: PMC7648372.
      Citations: 2     Fields:    Translation:HumansCells
    65. Chen K, Yang Q, Zha J, Deng M, Zhou Y, Fu G, Bi S, Feng L, Xu-Monette ZY, Chen XL, Fu G, Dai Y, Young KH, Xu B. Preclinical evaluation of a regimen combining chidamide and ABT-199 in acute myeloid leukemia. Cell Death Dis. 2020 09 18; 11(9):778. PMID: 32948748; PMCID: PMC7501858.
      Citations: 4     Fields:    Translation:Humans
    66. Xu-Monette ZY, Young KH. Therapeutic vaccines for aggressive B-cell lymphoma. Leuk Lymphoma. 2020 12; 61(13):3038-3051. PMID: 32840404; PMCID: PMC8344075.
      Citations: 3     Fields:    Translation:Humans
    67. Liu M, Wang X, Li W, Yu X, Flores-Villanueva P, Xu-Monette ZY, Li L, Zhang M, Young KH, Ma X, Li Y. Targeting PD-L1 in non-small cell lung cancer using CAR T cells. Oncogenesis. 2020 Aug 13; 9(8):72. PMID: 32792499; PMCID: PMC7426958.
      Citations: 15     
    68. Sechopoulos I, Boone JM, Dance D, van Engen R, Russo P, Young KC. Mammography dose estimates do not reflect any specific patient's breast dose. Eur J Radiol. 2020 10; 131:109216. PMID: 32810700.
      Citations:    Fields:    Translation:Humans
    69. Xu-Monette ZY, Zhang H, Zhu F, Tzankov A, Bhagat G, Visco C, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, You H, Huh J, Ponzoni M, Parsons BM, van Krieken JH, Winter JN, Hagemeister FB, Shahbaba B, De Dios I, Zhang H, Li Y, Xu B, Albitar M, Young KH, Ferreri AJM, M?ller MB, Piris MA. A refined cell-of-origin classifier with targeted NGS and artificial intelligence shows robust predictive value in DLBCL. Blood Adv. 2020 07 28; 4(14):3391-3404. PMID: 32722783; PMCID: PMC7391158.
      Citations: 6     Fields:    Translation:HumansCells
    70. Bao C, Tao X, Cui W, Yi B, Pan T, Young KH, Qian W. SARS-CoV-2 induced thrombocytopenia as an important biomarker significantly correlated with abnormal coagulation function, increased intravascular blood clot risk and mortality in COVID-19 patients. Exp Hematol Oncol. 2020; 9:16. PMID: 32695551; PMCID: PMC7366559.
      Citations:    
    71. Yang C, Xie M, Zhang K, Liu H, Liang A, Young KH, Qian W. Risk of HBV reactivation post CD19-CAR-T cell therapy in DLBCL patients with concomitant chronic HBV infection. Leukemia. 2020 11; 34(11):3055-3059. PMID: 32533094.
      Citations:    
    72. Sobhani N, D'Angelo A, Wang X, Young KH, Generali D, Li Y. Mutant p53 as an Antigen in Cancer Immunotherapy. Int J Mol Sci. 2020 Jun 08; 21(11). PMID: 32521648; PMCID: PMC7312027.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    73. Young KH. Good prognosis or poor prognosis, dose-intensive or less intensive: who decides for adults with T-lymphoblastic lymphoma/leukemia. Leukemia. 2020 11; 34(11):3075-3076. PMID: 32398791.
      Citations:    
    74. Washko GR, Nardelli P, Ash SY, Rahaghi FN, Vegas Sanchez-Ferrero G, Come CE, Dransfield MT, Kalhan R, Han MK, Bhatt SP, Wells JM, Pistenmaa CL, Diaz AA, Ross JC, Rennard S, Querejeta Roca G, Shah AM, Young K, Kinney GL, Hokanson JE, COPDGene Investigators, Agust? A, San Jos? Est?par R. Smaller Left Ventricle Size at Noncontrast CT Is Associated with Lower Mortality in COPDGene Participants. Radiology. 2020 07; 296(1):208-215. PMID: 32368963; PMCID: PMC7299752.
      Citations: 3     Fields:    Translation:Humans
    75. Zhou H, Xu-Monette ZY, Xiao L, Strati P, Hagemeister FB, He Y, Chen H, Li Y, Manyam GC, Li Y, Piris MA, Young KH, Montes-Moreno S. Prognostic factors, therapeutic approaches, and distinct immunobiologic features in patients with primary mediastinal large B-cell lymphoma on long-term follow-up. Blood Cancer J. 2020 05 04; 10(5):49. PMID: 32366834; PMCID: PMC7198569.
      Citations: 10     Fields:    Translation:HumansCells
    76. Yu X, Li W, Liu H, Deng Q, Wang X, Hu H, Xu-Monette ZY, Xiong W, Lu Z, Young KH, Wang W, Li Y. Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation. J Hematol Oncol. 2020 05 01; 13(1):40. PMID: 32357935; PMCID: PMC7193419.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    77. Huang X, Young KH, Guo W, Wang Y, Wang X, Xi Y, Wang L, Bai O. Identification of hepatitis B virus aetiologic antigens, HBx and Pre-S2, in diffuse large B-cell lymphoma. J Viral Hepat. 2020 09; 27(9):948-950. PMID: 32281709.
      Citations:    
    78. Keane C, Law SC, Gould C, Birch S, Sabdia MB, Merida de Long L, Thillaiyampalam G, Abro E, Tobin JW, Tan X, Xu-Monette ZY, Young KH, Gifford G, Gabreilli S, Stevenson WS, Gill A, Talaulikar D, Jain S, Hernandez A, Halliday SJ, Bird R, Cross D, Hertzberg M, Gandhi MK. LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma. Blood Adv. 2020 04 14; 4(7):1367-1377. PMID: 32267932; PMCID: PMC7160288.
      Citations: 27     Fields:    Translation:HumansCells
    79. Lowe KE, Hokanson JE, Make BJ, Pratte KA, Regan EA, Silverman EK, Young KA, Kinney GL, Crapo JD. Letter to the Editor: Response by Authors. Chronic Obstr Pulm Dis. 2020 Apr; 7(2):82-85. PMID: 32324979; PMCID: PMC7454025.
      Citations:    
    80. Due H, Br?ndum RF, Young KH, B?gsted M, Dybk?r K. MicroRNAs associated to single drug components of R-CHOP identifies diffuse large B-cell lymphoma patients with poor outcome and adds prognostic value to the international prognostic index. BMC Cancer. 2020 Mar 20; 20(1):237. PMID: 32192453; PMCID: PMC7082970.
      Citations:    
    81. Gallardo M, Malaney P, Aitken MJL, Zhang X, Link TM, Shah V, Alybayev S, Wu MH, Pageon LR, Ma H, Jacamo R, Yu L, Xu-Monette ZY, Steinman H, Lee HJ, Sarbassov D, Rapado I, Barton MC, Martinez-Lopez J, Bueso-Ramos C, Young KH, Post SM. Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas. J Natl Cancer Inst. 2020 01 01; 112(1):95-106. PMID: 31077320; PMCID: PMC7489062.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    82. Castaldi PJ, Boueiz A, Yun J, Estepar RSJ, Ross JC, Washko G, Cho MH, Hersh CP, Kinney GL, Young KA, Regan EA, Lynch DA, Criner GJ, Dy JG, Rennard SI, Casaburi R, Make BJ, Crapo J, Silverman EK, Hokanson JE, COPDGene Investigators. Machine Learning Characterization of COPD Subtypes: Insights From the COPDGene Study. Chest. 2020 05; 157(5):1147-1157. PMID: 31887283; PMCID: PMC7242638.
      Citations: 13     Fields:    Translation:Humans
    83. You L, Lin Q, Zhao J, Shi F, Young KH, Qian W. Whole-exome sequencing identifies novel somatic alterations associated with outcomes in idiopathic multicentric Castleman disease. Br J Haematol. 2020 03; 188(5):e64-e67. PMID: 31863597.
      Citations:    
    84. Shi K, Sun Q, Qiao C, Zhu H, Wang L, Wu J, Wang L, Fu J, Young KH, Fan L, Xia Y, Xu W, Li J. 98% IGHV gene identity is the optimal cutoff to dichotomize the prognosis of Chinese patients with chronic lymphocytic leukemia. Cancer Med. 2020 02; 9(3):999-1007. PMID: 31849198; PMCID: PMC6997101.
      Citations:    
    85. Deng Q, Hu H, Yu X, Liu S, Wang L, Chen W, Zhang C, Zeng Z, Cao Y, Xu-Monette ZY, Li L, Zhang M, Rosenfeld S, Bao S, Hsi E, Young KH, Lu Z, Li Y. Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant. Nat Commun. 2019 11 07; 10(1):5061. PMID: 31699989; PMCID: PMC6838078.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    86. Xu-Monette ZY, Li J, Xia Y, Crossley B, Bremel RD, Miao Y, Xiao M, Snyder T, Manyam GC, Tan X, Zhang H, Visco C, Tzankov A, Dybkaer K, Bhagat G, Tam W, You H, Hsi ED, van Krieken JH, Huh J, Ponzoni M, Winter JN, Medeiros JT, Xu B, Li Y, Kirsch I, Young KH, Ferreri AJM, M?ller MB, Piris MA. Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies. J Immunother Cancer. 2019 10 22; 7(1):272. PMID: 31640780; PMCID: PMC6806565.
      Citations: 7     Fields:    Translation:HumansCells
    87. Yu L, Yu TT, Young KH. Cross-talk between Myc and p53 in B-cell lymphomas. Chronic Dis Transl Med. 2019 Sep; 5(3):139-154. PMID: 31891126; PMCID: PMC6926120.
      Citations:    
    88. Young KH. Hematopoietic stem cell transplantation for adults with T-cell lymphoblastic lymphoma: can we successfully step into the era of precision medicine? Leukemia. 2020 04; 34(4):1213-1214. PMID: 31641192.
      Citations:    
    89. Kim DH, Medeiros LJ, Aung PP, Young KH, Miranda RN, Ok CY. Mantle Cell Lymphoma Involving Skin: A Clinicopathologic Study of 37 Cases. Am J Surg Pathol. 2019 10; 43(10):1421-1428. PMID: 31219818.
      Citations: 2     Fields:    Translation:Humans
    90. Miao Y, Medeiros LJ, Li Y, Li J, Young KH. Genetic alterations and their clinical implications in DLBCL. Nat Rev Clin Oncol. 2019 10; 16(10):634-652. PMID: 31127191.
      Citations: 61     Fields:    Translation:Humans
    91. Soderquist CR, Patel N, Murty VV, Betman S, Aggarwal N, Young KH, Xerri L, Leeman-Neill R, Lewis SK, Green PH, Hsiao S, Mansukhani MM, Hsi ED, de Leval L, Alobeid B, Bhagat G. Genetic and phenotypic characterization of indolent T-cell lymphoproliferative disorders of the gastrointestinal tract. Haematologica. 2020 07; 105(7):1895-1906. PMID: 31558678; PMCID: PMC7327650.
      Citations:    
    92. Li Z, Zhang X, Xue W, Zhang Y, Li C, Song Y, Mei M, Lu L, Wang Y, Zhou Z, Jin M, Bian Y, Zhang L, Wang X, Li L, Li X, Fu X, Sun Z, Wu J, Nan F, Chang Y, Yan J, Yu H, Feng X, Wang G, Zhang D, Fu X, Zhang Y, Young KH, Li W, Zhang M. Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma. Nat Commun. 2019 09 16; 10(1):4209. PMID: 31527657; PMCID: PMC6746819.
      Citations:    
    93. Li Z, Song Y, Zhang Y, Li C, Wang Y, Xue W, Lu L, Jin M, Zhou Z, Wang X, Li L, Zhang L, Li X, Fu X, Sun Z, Wu J, Zhang X, Yu H, Nan F, Chang Y, Yan J, Feng X, Wu X, Wang G, Zhang D, Li W, Li F, Zhang Y, Young KH, Zhang M. Genomic and outcome analysis of adult T-cell lymphoblastic lymphoma. Haematologica. 2020 03; 105(3):e107-e110. PMID: 31413085; PMCID: PMC7049353.
      Citations:    
    94. Kazma J, Johnson C, Jain N, Gali VL, Young KH, Jazaeri AA. B-cell acute lymphoblastic leukemia/lymphoma in relapse presenting as a cervical mass: A case report and review of literature. Gynecol Oncol Rep. 2019 Aug; 29:94-97. PMID: 31467959; PMCID: PMC6710557.
      Citations:    
    95. Lyapichev KA, Medeiros LJ, Evans MG, Liu H, Miranda AR, Hunt KK, Clemens MW, Stewart JM, Amin MB, Quesada AE, Chai SM, Di Napoli A, Yoga A, Dave SK, Wistuba II, Wu Y, Bueso-Ramos CE, Schlette EJ, Ferrufino-Schmidt MC, Loghavi S, Khoury JD, Young KH, Miranda RN, Pi?a-Oviedo S. A proposal for pathologic processing of breast implant capsules in patients with suspected breast implant anaplastic large cell lymphoma. Mod Pathol. 2020 03; 33(3):367-379. PMID: 31383966; PMCID: PMC7489290.
      Citations: 6     Fields:    Translation:Humans
    96. Wang L, Deng Q, Hu H, Liu M, Gong Z, Zhang S, Xu-Monette ZY, Lu Z, Young KH, Ma X, Li Y. Glyphosate induces benign monoclonal gammopathy and promotes multiple myeloma progression in mice. J Hematol Oncol. 2019 07 05; 12(1):70. PMID: 31277689; PMCID: PMC6612199.
      Citations: 4     Fields:    Translation:HumansAnimals
    97. Liu H, He J, Koh SP, Zhong Y, Liu Z, Wang Z, Zhang Y, Li Z, Tam BT, Lin P, Xiao M, Young KH, Amini B, Starbuck MW, Lee HC, Navone NM, Davis RE, Tong Q, Bergsagel PL, Hou J, Yi Q, Orlowski RZ, Gagel RF, Yang J. Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease. Sci Transl Med. 2019 05 29; 11(494). PMID: 31142679; PMCID: PMC6999853.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    98. Lutz SM, Frederiksen B, Begum F, McDonald MN, Cho MH, Hobbs BD, Parker MM, DeMeo DL, Hersh CP, Ehringer MA, Young K, Jiang L, Foreman MG, Kinney GL, Make BJ, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH, Hokanson JE, ECLIPSE and COPDGene Investigators. Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls. Nicotine Tob Res. 2019 05 21; 21(6):714-722. PMID: 29767774; PMCID: PMC6528143.
      Citations: 6     Fields:    Translation:Humans
    99. Cai Q, Cai J, Fang Y, Young KH. Epstein-Barr Virus-Positive Natural Killer/T-Cell Lymphoma. Front Oncol. 2019; 9:386. PMID: 31139570; PMCID: PMC6527808.
      Citations:    
    100. Pecciarini L, Dirnhofer S, Tzankov A, Miranda RN, Young KH, Traverse-Glehen A, Gaidano G, Swerdlow SH, Gascoyne R, Rabadan R, Ponzoni M, Bhagat G, Zucca E, Cascione L, Rinaldi A, Bruscaggin A, Tarantelli C, Arribas AJ, Kwee I, Mensah AA, Spina V, Chung EYL, di Bergamo LT, Rossi D, Bertoni F. Novel insights into the genetics and epigenetics of MALT lymphoma unveiled by next generation sequencing analyses. Haematologica. 2019 12; 104(12):e558-e561. PMID: 31018978; PMCID: PMC6959164.
      Citations: 22     Fields:    Translation:Humans
    101. Due H, Sch?nherz AA, Ry? L, Primo MN, Jespersen DS, Thomsen EA, Roug AS, Xiao M, Tan X, Pang Y, Young KH, B?gsted M, Mikkelsen JG, Dybk?r K. MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma. Blood Adv. 2019 04 09; 3(7):1185-1196. PMID: 30967394; PMCID: PMC6457225.
      Citations:    
    102. James JA, Chen H, Young KA, Bemis EA, Seifert J, Bourn RL, Deane KD, Demoruelle MK, Feser M, O'Dell JR, Weisman MH, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Harley JB, Robinson W, Hafler DA, O'Connor KC, Buckner J, Guthridge JM, Norris JM, Holers VM. Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients. EBioMedicine. 2019 Apr; 42:76-85. PMID: 30952617; PMCID: PMC6491794.
      Citations: 6     Fields:    Translation:Humans
    103. Chamoun K, Ledesma C, Young KH, Jabbour EJ, Alatrash G, Anderlini P, Bashir Q, Ciurea SO, Marin D, Molldrem JJ, Olson AL, Oran B, Popat UR, Rondon G, Champlin RE, Gulbis AM, Khouri IF, Milton DR. Allogeneic Transplantation after Myeloablative Rituximab/BEAM ? Bortezomib for Patients with Relapsed/Refractory Lymphoid Malignancies: 5-Year Follow-Up Results. Biol Blood Marrow Transplant. 2019 07; 25(7):1347-1354. PMID: 30826465; PMCID: PMC6615973.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    104. Miao Y, Medeiros LJ, Xu-Monette ZY, Li J, Young KH. Dysregulation of Cell Survival in Diffuse Large B Cell Lymphoma: Mechanisms and Therapeutic Targets. Front Oncol. 2019; 9:107. PMID: 30881917; PMCID: PMC6406015.
      Citations: 17     
    105. Xu-Monette ZY, Xiao M, Au Q, Padmanabhan R, Xu B, Hoe N, Torres-Ruiz R, Manyam GC, Visco C, Miao Y, Tan X, Zhang H, Tzankov A, Wang J, Tam W, You H, Bhagat G, Hsi ED, Ponzoni M, van Krieken JH, Winter JN, Westin JR, Pham LV, Medeiros LJ, Rassidakis GZ, Li Y, Freeman GJ, Young KH, Rodr?guez-Perales S, Dybk?r K, Ferreri AJM, M?ller MB, Piris MA. Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL. Cancer Immunol Res. 2019 04; 7(4):644-657. PMID: 30745366.
      Citations: 44     Fields:    Translation:HumansCells
    106. Li L, Sun R, Miao Y, Tran T, Adams L, Roscoe N, Xu B, Manyam GC, Tan X, Zhang H, Xiao M, Tzankov A, Visco C, Dybkaer K, Bhagat G, Tam W, Hsi ED, van Krieken JH, You H, Huh J, Ponzoni M, Zhang M, Winter JN, Medeiros LJ, Rassidakis GZ, Vaupel CA, Li Y, Dakappagari N, Xu-Monette ZY, Young KH, Ferreri AJM, M?ller MB, Piris MA. PD-1/PD-L1 expression and interaction by automated quantitative immunofluorescent analysis show adverse prognostic impact in patients with diffuse large B-cell lymphoma having T-cell infiltration: a study from the International DLBCL Consortium Program. Mod Pathol. 2019 06; 32(6):741-754. PMID: 30666052.
      Citations: 15     Fields:    Translation:HumansCells
    107. Cai Q, Fang Y, Young KH. Primary Central Nervous System Lymphoma: Molecular Pathogenesis and Advances in Treatment. Transl Oncol. 2019 Mar; 12(3):523-538. PMID: 30616219; PMCID: PMC6371000.
      Citations:    
    108. Li Z, Lan X, Li C, Zhang Y, Wang Y, Xue W, Lu L, Jin M, Zhou Z, Wang X, Li L, Zhang L, Li X, Fu X, Sun Z, Wu J, Zhang X, Yu H, Nan F, Chang Y, Yan J, Wu X, Wang G, Zhang D, Zhang Y, Young KH, Zhang M. Recurrent PDGFRB mutations in unicentric Castleman disease. Leukemia. 2019 04; 33(4):1035-1038. PMID: 30607019; PMCID: PMC6484698.
      Citations:    
    109. Wang L, Kumar M, Deng Q, Wang X, Liu M, Gong Z, Zhang S, Ma X, Xu-Monette ZY, Xiao M, Yi Q, Young KH, Ramos KS, Li Y. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces peripheral blood abnormalities and plasma cell neoplasms resembling multiple myeloma in mice. Cancer Lett. 2019 01; 440-441:135-144. PMID: 30343114; PMCID: PMC6238649.
      Citations: 4     Fields:    Translation:Animals
    110. Kinney GL, Santorico SA, Young KA, Cho MH, Castaldi PJ, Ross JC, Dy JG, Make BJ, Regan EA, Lynch DA, Everett DC, Lutz SM, Silverman EK, Washko GR, Crapo JD, Hokanson JE, COPDGene Investigators, San Jos? Est?par R. Identification of Chronic Obstructive Pulmonary Disease Axes That Predict All-Cause Mortality: The COPDGene Study. Am J Epidemiol. 2018 10 01; 187(10):2109-2116. PMID: 29771274; PMCID: PMC6166205.
      Citations: 14     Fields:    Translation:Humans
    111. Li L, Zhang J, Chen J, Xu-Monette ZY, Miao Y, Xiao M, Young KH, Wang S, Medeiros LJ, Wang M, Ford RJ, Pham LV. B-cell receptor-mediated NFATc1 activation induces IL-10/STAT3/PD-L1 signaling in diffuse large B-cell lymphoma. Blood. 2018 10 25; 132(17):1805-1817. PMID: 30209121; PMCID: PMC6634963.
      Citations: 29     Fields:    Translation:HumansCells
    112. Zhang J, Medeiros LJ, Young KH. Cancer Immunotherapy in Diffuse Large B-Cell Lymphoma. Front Oncol. 2018; 8:351. PMID: 30250823; PMCID: PMC6140403.
      Citations: 39     
    113. Huang Q, Xi J, Wang L, Wang X, Ma X, Deng Q, Lu Y, Kumar M, Zhou Z, Li L, Zeng Z, Young KH, Yi Q, Zhang M, Li Y. Correction to: miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy. J Hematol Oncol. 2018 Jul 03; 11(1):90. PMID: 29970126; PMCID: PMC6030738.
      Citations:    
    114. Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM. EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2018 update on diagnosis, risk-stratification and management. Am J Hematol. 2018 07; 93(7):953-962. PMID: 29984868.
      Citations: 26     Fields:    Translation:HumansCells
    115. Yin L, Xu-Monette ZY, Brock J, Li Y, Young KH. Different prevalence and clinical outcome of Epstein-Barr virus positive diffuse large B-cell lymphoma between North American and non-Western populations. Ann Transl Med. 2018 Jun; 6(11):236. PMID: 30023399; PMCID: PMC6036001.
      Citations: 2     
    116. Elangovan P, Mackenzie A, Dance DR, Young KC, Wells K. Lesion detectability in 2D-mammography and digital breast tomosynthesis using different targets and observers. Phys Med Biol. 2018 05 04; 63(9):095014. PMID: 29637906.
      Citations:    Fields:    Translation:Humans
    117. Wang X, Cao X, Sun R, Tang C, Tzankov A, Zhang J, Manyam GC, Xiao M, Miao Y, Jabbar K, Tan X, Pang Y, Visco C, Xie Y, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WWL, van Krieken JH, Huh J, Ponzoni M, Parsons BM, Winter JN, Li S, Miranda RN, Medeiros LJ, Li Y, Xu-Monette ZY, Young KH, Ferreri AJM, M?ller MB, Piris MA. Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma. Neoplasia. 2018 06; 20(6):574-593. PMID: 29734016; PMCID: PMC5994742.
      Citations: 22     Fields:    Translation:HumansCells
    118. Yu X, Li W, Deng Q, Li L, Hsi ED, Young KH, Zhang M, Li Y. MYD88 L265P Mutation in Lymphoid Malignancies. Cancer Res. 2018 05 15; 78(10):2457-2462. PMID: 29703722.
      Citations:    
    119. Huang Q, Xia J, Wang L, Wang X, Ma X, Deng Q, Lu Y, Kumar M, Zhou Z, Li L, Zeng Z, Young KH, Yi Q, Zhang M, Li Y. miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy. J Hematol Oncol. 2018 04 23; 11(1):58. PMID: 29685162; PMCID: PMC5914051.
      Citations:    
    120. Pham LV, Huang S, Zhang H, Zhang J, Bell T, Zhou S, Pogue E, Ding Z, Lam L, Westin J, Davis RE, Young KH, Medeiros LJ, Ford RJ, Nomie K, Zhang L, Wang M. Strategic Therapeutic Targeting to Overcome Venetoclax Resistance in Aggressive B-cell Lymphomas. Clin Cancer Res. 2018 08 15; 24(16):3967-3980. PMID: 29666304.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    121. Alatrash G, Perakis AA, Kerros C, Peters HL, Sukhumalchandra P, Zhang M, Jakher H, Zope M, Patenia R, Sergeeva A, Yi S, Young KH, Philips AV, Cernosek AM, Garber HR, Qiao N, Weng J, St John LS, Lu S, Clise-Dwyer K, Mittendorf EA, Ma Q, Molldrem JJ. Targeting the Leukemia Antigen PR1 with Immunotherapy for the Treatment of Multiple Myeloma. Clin Cancer Res. 2018 07 15; 24(14):3386-3396. PMID: 29661776.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    122. Sarasquete ME, Panizo C, Morscio J, Martinez A, Alcoceba M, Fresquet V, Gonzalez-Farre B, Paiva B, Young KH, Robles EF, Roa S, Celay J, Larrayoz M, Rossi D, Gaidano G, Montes-Moreno S, Piris MA, Balanzategui A, Jimenez C, Rodriguez I, Calasanz MJ, Larrayoz MJ, Segura V, Yi S, Li J, Zhang M, Xu-Monette ZY, Puig-Moron N, Orfao A, Hernandez-Rivas JM, Miguel JS, Prosper F, Tousseyn T, Sagaert X, Gonzalez M, Martinez-Climent JA, Garc?a-Barchino MJ, Garcia-Mu?oz R, Rabasa MP, B?ttcher S. Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia. J Pathol. 2018 05; 245(1):61-73. PMID: 29464716.
      Citations: 12     Fields:    Translation:HumansCells
    123. Xi J, Huang Q, Wang L, Ma X, Deng Q, Kumar M, Zhou Z, Li L, Zeng Z, Young KH, Zhang M, Li Y. miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy. Oncogene. 2018 06; 37(23):3151-3165. PMID: 29540832; PMCID: PMC5993583.
      Citations:    
    124. Sun RF, Yu QQ, Young KH. Critically dysregulated signaling pathways and clinical utility of the?pathway biomarkers in lymphoid malignancies. Chronic Dis Transl Med. 2018 Mar; 4(1):29-44. PMID: 29756121; PMCID: PMC5938286.
      Citations:    
    125. Young KH, Medeiros LJ, Thakral B, Quesada AE. Indolent T-lymphoblastic proliferation associated with low grade follicular dendritic cell sarcoma and Castleman disease. Pathology. 2018 Apr; 50(3):351-352. PMID: 29486963.
      Citations: 2     Fields:    Translation:HumansCells
    126. Ferrufino-Schmidt MC, Medeiros LJ, Liu H, Clemens MW, Hunt KK, Lofts J, Amin MB, Ming Chai S, Morine A, Di Napoli A, Dogan A, Parkash V, Bhagat G, Tritz D, Quesada AE, Pina-Oviedo S, Hu Q, Garcia-Gomez FJ, Jose Borrero J, Horna P, Thakral B, Narbaitz M, Hughes RC, Yang LJ, Fromm JR, Wu D, Zhang D, Sohani AR, Hunt J, Vadlamani IU, Morgan EA, Ferry JA, Szigeti R, C Tardio J, Granados R, Dertinger S, Offner FA, Pircher A, Hosry J, Young KH, Miranda RN, Laurent C. Clinicopathologic Features and Prognostic Impact of Lymph Node Involvement in Patients With Breast Implant-associated Anaplastic Large Cell Lymphoma. Am J Surg Pathol. 2018 03; 42(3):293-305. PMID: 29194092; PMCID: PMC7500854.
      Citations: 22     Fields:    Translation:Humans
    127. Chahoud J, Sui D, Erwin WD, Gulbis AM, Korbling M, Zhang M, Ahmed S, Alatrash G, Anderlini P, Ciurea SO, Oran B, Fayad LE, Bassett RL, Jabbour EJ, Medeiros LJ, Macapinlac HA, Young KH, Khouri IF. Updated Results of Rituximab Pre- and Post-BEAM with or without 90Yttrium Ibritumomab Tiuxetan during Autologous Transplant for Diffuse Large B-cell Lymphoma. Clin Cancer Res. 2018 05 15; 24(10):2304-2311. PMID: 29476021; PMCID: PMC5955837.
      Citations: 2     Fields:    Translation:Humans
    128. Li X, Cheng Y, Zhang M, Yan J, Li L, Fu X, Zhang X, Chang Y, Sun Z, Yu H, Zhang L, Wang X, Wu J, Li Z, Nan F, Tian L, Li W, Young KH. Activity of pembrolizumab in relapsed/refractory NK/T-cell lymphoma. J Hematol Oncol. 2018 01 31; 11(1):15. PMID: 29386072; PMCID: PMC5793390.
      Citations:    
    129. Li L, Xiao S, Zhang L, Li X, Fu X, Wang X, Wu J, Sun Z, Zhang X, Chang Y, Nan F, Yan J, Li Z, Shi M, Young KH, Zhang M. An open label, single-armed, exploratory study of apatinib (a novel VEGFR-2 tyrosine kinase inhibitor) in patients with relapsed or refractory non-Hodgkin lymphoma. Oncotarget. 2018 Mar 23; 9(22):16213-16219. PMID: 29662638; PMCID: PMC5882329.
      Citations:    
    130. Xu-Monette ZY, Zhang M, Li J, Young KH. PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response? Front Immunol. 2017; 8:1597. PMID: 29255458; PMCID: PMC5723106.
      Citations: 98     Fields:    
    131. Li S, Young KH, Medeiros LJ. Diffuse large B-cell lymphoma. Pathology. 2018 Jan; 50(1):74-87. PMID: 29167021.
      Citations: 144     Fields:    Translation:Humans
    132. Xu-Monette ZY, Zhou J, Young KH. PD-1 expression and clinical PD-1 blockade in B-cell lymphomas. Blood. 2018 01 04; 131(1):68-83. PMID: 29118007; PMCID: PMC5755041.
      Citations: 144     Fields:    Translation:HumansAnimals
    133. Mackenzie A, Young KC, Dance DR, Bouwman RW, van Engen RE, Broeders MJM, den Heeten GJ, Veldkamp WJH. Toward image quality assessment in mammography using model observers: Detection of a calcification-like object. Med Phys. 2017 Nov; 44(11):5726-5739. PMID: 28837225.
      Citations: 4     Fields:    Translation:Humans
    134. Hu Z, Sun Y, Schlette EJ, Tang G, Li S, Xu J, Yin CC, Young KH, Patel KP, Miranda RN, Goswami M, Wang M, Jorgensen JL, Medeiros LJ, Wang SA. CD200 expression in mantle cell lymphoma identifies a unique subgroup of patients with frequent IGHV mutations, absence of SOX11 expression, and an indolent clinical course. Mod Pathol. 2018 02; 31(2):327-336. PMID: 28984300.
      Citations: 9     Fields:    Translation:Humans
    135. Xu-Monette ZY, Yi S, Dabaja BS, Manyam GC, Westin J, Fowler N, Miranda RN, Zhang M, Ferry JA, Medeiros LJ, Harris NL, Young KH, Li X. Primary Bone Lymphoma Exhibits a Favorable Prognosis and Distinct Gene Expression Signatures Resembling Diffuse Large B-Cell Lymphoma Derived From Centrocytes in the Germinal Center. Am J Surg Pathol. 2017 Oct; 41(10):1309-1321. PMID: 28817403.
      Citations: 8     Fields:    Translation:HumansCells
    136. Visco C, Wang J, Tisi MC, Deng L, D'Amore ESG, Tzankov A, Montes-Moreno S, Bhagat G, Hsi ED, van Krieken JH, Ponzoni M, Piris MA, Medeiros LJ, Xu-Monette ZY, Young KH, Dybk?r K, Ferreri AJM, M?ller MB. Hepatitis C virus positive diffuse large B-cell lymphomas have distinct molecular features and lack BCL2 translocations. Br J Cancer. 2017 Nov 21; 117(11):1685-1688. PMID: 28949959; PMCID: PMC5729442.
      Citations: 4     Fields:    Translation:HumansCells
    137. Liu W, Chen J, Tamayo AT, Ruan C, Li L, Zhou S, Shen C, Young KH, Westin J, Davis RE, Hu S, Medeiros LJ, Ford RJ, Pham LV. Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma. Oncotarget. 2018 Jan 02; 9(1):346-360. PMID: 29416618; PMCID: PMC5787470.
      Citations: 5     Fields:    
    138. Wu H, Medeiros LJ, Young KH. Apoptosis signaling and BCL-2 pathways provide opportunities for novel targeted therapeutic strategies in hematologic malignances. Blood Rev. 2018 01; 32(1):8-28. PMID: 28802908.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    139. Wang J, Xu-Monette ZY, Jabbar KJ, Shen Q, Manyam GC, Tzankov A, Visco C, Wang J, Montes-Moreno S, Tam W, Bhagat G, Hsi ED, van Krieken JH, Ponzoni M, Wang S, Piris MA, Medeiros LJ, Li Y, Pham LV, Young KH, Dybk?r K, Ferreri AJM, M?ller MB. AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma. Am J Pathol. 2017 Aug; 187(8):1700-1716. PMID: 28627414; PMCID: PMC5530910.
      Citations: 21     Fields:    Translation:HumansCells
    140. Li L, Duan W, Zhang L, Li X, Fu X, Wang X, Wu J, Sun Z, Zhang X, Chang Y, Nan F, Yan J, Li Z, Young KH, Zhang M. The efficacy and safety of gemcitabine, cisplatin, prednisone, thalidomide versus CHOP in patients with newly diagnosed peripheral T-cell lymphoma with analysis of biomarkers. Br J Haematol. 2017 09; 178(5):772-780. PMID: 28597542.
      Citations:    
    141. Ho JC, Dabaja BS, Milgrom SA, Smith GL, Reddy JP, Mazloom A, Young KH, Deng L, Medeiros LJ, Dong W, Allen PK, Andraos TY, Fowler NH, Nastoupil LJ, Oki Y, Fayad LE, Turturro F, Neelapu SS, Westin J, Hagemeister FB, Rodriguez MA, Pinnix CC. Radiation therapy improves survival in patients with testicular diffuse large B-cell lymphoma. Leuk Lymphoma. 2017 12; 58(12):2833-2844. PMID: 28482717; PMCID: PMC6042648.
      Citations: 5     Fields:    Translation:Humans
    142. Ok CY, Young KH. Checkpoint inhibitors in hematological malignancies. J Hematol Oncol. 2017 05 08; 10(1):103. PMID: 28482851; PMCID: PMC5422942.
      Citations: 55     Fields:    Translation:HumansCells
    143. Elangovan P, Mackenzie A, Dance DR, Young KC, Cooke V, Wilkinson L, Given-Wilson RM, Wallis MG, Wells K. Design and validation of realistic breast models for use in multiple alternative forced choice virtual clinical trials. Phys Med Biol. 2017 04 07; 62(7):2778-2794. PMID: 28291738.
      Citations: 6     Fields:    Translation:Humans
    144. Torres-Cabala CA, Patel KP, Merril ED, Duvic M, Quesada A, Prieto VG, Aung PP, Loghavi S, Young KH, Hu S, Ferrufino-Schmidt MC, Tetzlaff M, Li S, Medeiros LJ, Miranda RN, Agbay RL. Immunophenotypic Shifts in Primary Cutaneous ?d T-Cell Lymphoma Suggest Antigenic Modulation: A Study of Sequential Biopsy Specimens. Am J Surg Pathol. 2017 Apr; 41(4):431-445. PMID: 28248813.
      Citations: 2     Fields:    Translation:HumansCells
    145. Cai Q, Tu M, Xu-Monette ZY, Sun R, Manyam GC, Xu X, Tzankov A, Hsi ED, Medeiros LJ, Ok CY, Young KH, M?ller MB. NF-?B p50 activation associated with immune dysregulation confers poorer survival for diffuse large B-cell lymphoma patients with wild-type p53. Mod Pathol. 2017 06; 30(6):854-876. PMID: 28281555.
      Citations: 6     Fields:    Translation:HumansCells
    146. Montalban-Bravo G, Benton CB, Wang SA, Ravandi F, Kadia T, Cortes J, Daver N, Takahashi K, DiNardo C, Jabbour E, Borthakur G, Konopleva M, Pierce S, Bueso-Ramos C, Patel K, Kornblau S, Kantarjian H, Young KH, Garcia-Manero G, Andreeff M. More than 1 TP53 abnormality is a dominant characteristic of pure erythroid leukemia. Blood. 2017 05 04; 129(18):2584-2587. PMID: 28246192; PMCID: PMC5418636.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    147. Ok CY, Young KH. Targeting the programmed death-1 pathway in lymphoid neoplasms. Cancer Treat Rev. 2017 Mar; 54:99-109. PMID: 28242522; PMCID: PMC5815314.
      Citations: 12     Fields:    Translation:HumansCells
    148. Agbay R, Miranda RN, Aung PP, Tetzlaff MT, Young KH, Curry JL, Nagarajan P, Ivan D, Prieto VG, Medeiros LJ, Duvic M, Torres-Cabala CA, Merrill ED. Primary Cutaneous T-Cell Lymphomas Showing Gamma-Delta (?d) Phenotype and Predominantly Epidermotropic Pattern are Clinicopathologically Distinct From Classic Primary Cutaneous ?d T-Cell Lymphomas. Am J Surg Pathol. 2017 Feb; 41(2):204-215. PMID: 27879514.
      Citations: 9     Fields:    Translation:Humans
    149. Medeiros LJ, Chen Z, Chen W, Li S, Konoplev SN, Lu X, Pham LV, Young KH, Wang W, Hu S, Hu Z. Mantle Cell Lymphoma With MYC Rearrangement: A Report of 17 Patients. Am J Surg Pathol. 2017 Feb; 41(2):216-224. PMID: 27776009.
      Citations: 16     Fields:    Translation:Humans
    150. Yu L, Tu M, Cortes J, Xu-Monette ZY, Miranda RN, Zhang J, Orlowski RZ, Neelapu S, Boddu PC, Akosile MA, Uldrick TS, Yarchoan R, Medeiros LJ, Li Y, Fajgenbaum DC, Young KH. Clinical and pathological characteristics of HIV- and HHV-8-negative Castleman disease. Blood. 2017 03 23; 129(12):1658-1668. PMID: 28100459; PMCID: PMC5364343.
      Citations: 50     Fields:    Translation:HumansCells
    151. Medeiros LJ, Wang SA, Tang G, Bueso-Ramos CE, Jorgensen JL, Bhagat G, Chen W, Li S, Young KH, Miranda RN, Yabe M. Distinguishing Between Hepatosplenic T-cell Lymphoma and ?d T-cell Large Granular Lymphocytic Leukemia: A Clinicopathologic, Immunophenotypic, and Molecular Analysis. Am J Surg Pathol. 2017 01; 41(1):82-93. PMID: 27755009.
      Citations: 11     Fields:    Translation:Humans
    152. Sun R, Wang J, Young KH. Oncogenic Signaling Pathways and Pathway-Based Therapeutic Biomarkers in Lymphoid Malignancies. Crit Rev Oncog. 2017; 22(5-6):527-557. PMID: 29604930; PMCID: PMC5961736.
      Citations:    
    153. Zhang M, Xu-Monette ZY, Li L, Manyam GC, Visco C, Tzankov A, Wang J, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, Han van Krieken J, Huh J, Ponzoni M, Parsons BM, Winter JN, Piris MA, Medeiros LJ, Pham LV, Young KH, Ferreri AJ, M?ller MB. RelA NF-?B subunit activation as a therapeutic target in diffuse large B-cell lymphoma. Aging (Albany NY). 2016 12 08; 8(12):3321-3340. PMID: 27941215; PMCID: PMC5270671.
      Citations: 13     Fields:    Translation:HumansCells
    154. Pham LV, Bryant JL, Mendez R, Chen J, Tamayo AT, Xu-Monette ZY, Young KH, Manyam GC, Yang D, Medeiros LJ, Ford RJ. Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma. Oncotarget. 2016 Dec 06; 7(49):80599-80611. PMID: 27716624; PMCID: PMC5348344.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    155. Xu-Monette ZY, Li L, Byrd JC, Jabbar KJ, Manyam GC, Maria de Winde C, van den Brand M, Tzankov A, Visco C, Wang J, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, Huh J, Ponzoni M, Parsons BM, Winter JN, Wang M, Hagemeister FB, Han van Krieken J, Medeiros LJ, Li Y, van Spriel AB, Young KH, Ferreri AJ, M?ller MB, Piris MA. Assessment of CD37 B-cell antigen and cell of origin significantly improves risk prediction in diffuse large B-cell lymphoma. Blood. 2016 12 29; 128(26):3083-3100. PMID: 27760757; PMCID: PMC5201094.
      Citations: 24     Fields:    Translation:HumansCells
    156. Yabe M, Medeiros LJ, Daneshbod Y, Davanlou M, Bueso-Ramos CE, Moran EJ, Young KH, Miranda RN. Hepatosplenic T-cell lymphoma arising in patients with immunodysregulatory disorders: a study of 7 patients who did not receive tumor necrosis factor-a inhibitor therapy and literature review. Ann Diagn Pathol. 2017 Feb; 26:16-22. PMID: 28038706; PMCID: PMC5560101.
      Citations: 9     Fields:    Translation:Humans
    157. Yu L, Li L, Medeiros LJ, Young KH. NF-?B signaling pathway and its potential as a target for therapy in lymphoid neoplasms. Blood Rev. 2017 03; 31(2):77-92. PMID: 27773462; PMCID: PMC5382109.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    158. Zhang L, Jia S, Ma Y, Li L, Li X, Wang X, Fu X, Ma W, Qin Y, Li W, Wu J, Sun Z, Zhang X, Nan F, Chang Y, Li Z, Zhang D, Wang G, Yan J, Su L, Wang J, Xue H, Young KH, Zhang M. Efficacy and safety of cisplatin, dexamethasone, gemcitabine and pegaspargase (DDGP) regimen in newly diagnosed, advanced-stage extranodal natural killer/T-cell lymphoma: interim analysis of a phase 4 study NCT01501149. Oncotarget. 2016 Aug 23; 7(34):55721-55731. PMID: 27384676; PMCID: PMC5342448.
      Citations:    
    159. Tang Z, Medeiros LJ, Yin CC, Wang W, Lu X, Young KH, Khoury JD, Tang G. Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms: a diagnostic dilemma for clinical cytogeneticists. Mol Cytogenet. 2016; 9:62. PMID: 27508005; PMCID: PMC4977628.
      Citations: 4     
    160. Sun R, Medeiros LJ, Young KH. Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine. Mod Pathol. 2016 10; 29(10):1118-42. PMID: 27363492.
      Citations: 10     Fields:    Translation:Humans
    161. Sasaki K, Popat U, Jain P, Kadia T, Patel K, Patel K, Jain N, Takahashi K, Young K, Miranda RN, Oo TH, Lu H, Pemmaraju N. Successful treatment of aplastic anemia-paroxysmal nocturnal hemoglobinuria associated with eosinophilic fasciitis with matched unrelated donor allogeneic peripheral blood stem cell transplantation. Clin Case Rep. 2016 Aug; 4(8):765-7. PMID: 27525080; PMCID: PMC4974424.
      Citations: 1     
    162. Young KA, Munroe ME, Guthridge JM, Kamen DL, Niewold TB, Gilkeson GS, Weisman MH, Ishimori ML, Kelly J, Gaffney PM, Sivils KH, Lu R, Wallace DJ, Karp DR, Harley JB, James JA, Norris JM. Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. Ann Rheum Dis. 2017 Jan; 76(1):153-158. PMID: 27283331; PMCID: PMC5360632.
      Citations: 13     Fields:    Translation:Humans
    163. Medeiros LJ, Tang G, Wang SA, Ahmed S, Nieto Y, Hu S, Bhagat G, Oki Y, Patel KP, Routbort M, Luthra R, Fanale MA, Bueso-Ramos CE, Jorgensen JL, Vega F, Chen W, Hoehn D, Konoplev S, Milton DR, Wistuba I, Li S, You MJ, Young KH, Miranda RN, Yabe M. Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases. Am J Surg Pathol. 2016 May; 40(5):676-88. PMID: 26872013.
      Citations: 14     Fields:    Translation:HumansCells
    164. Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM. EBV-positive diffuse large B-cell lymphoma of the elderly: 2016 update on diagnosis, risk-stratification, and management. Am J Hematol. 2016 May; 91(5):529-37. PMID: 27093913.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    165. Loghavi S, Wang SA, Medeiros LJ, Jorgensen JL, Li X, Xu-Monette ZY, Miranda RN, Young KH. Immunophenotypic and diagnostic characterization of angioimmunoblastic T-cell lymphoma by advanced flow cytometric technology. Leuk Lymphoma. 2016 12; 57(12):2804-2812. PMID: 27105079; PMCID: PMC5142610.
      Citations: 7     Fields:    Translation:HumansCells
    166. Wu W, Zhu H, Fu Y, Shen W, Miao K, Hong M, Xu W, Fan L, Young KH, Liu P, Li J. High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid. Oncotarget. 2016 Apr 19; 7(16):21631-43. PMID: 26950276; PMCID: PMC5008311.
      Citations:    
    167. Francisco M, Malatxeberria S, Montalban C, Garcia J, Ruiz-Marcellan MC, Mollejo M, Grande C, Richards KL, Hsi ED, Tzankov A, Visco C, Xu-Monette ZY, Cao X, Young KH, Conde E, Montes-Moreno S, Batlle-L?pez A, Gonz?lez de Villambros?a S, S?ez A, S?nchez L, Gonz?lez-Barca E, L?pez-Hern?ndez A, Piris M?. Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy: GCB/non-GCB by immunohistochemistry is still a robust and feasible marker. Oncotarget. 2016 Apr 05; 7(14):18036-49. PMID: 26910115; PMCID: PMC4951269.
      Citations: 6     Fields:    Translation:Humans
    168. Xu-Monette ZY, Deng Q, Manyam GC, Tzankov A, Li L, Xia Y, Wang XX, Zou D, Visco C, Li J, Zhang L, Liang H, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Parsons BM, Wang SA, Miranda RN, Winter JN, Medeiros LJ, Li Y, Young KH, Dybk?r K, Montes-Moreno S, Ferreri AJ, M?ller MB, Piris MA. Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma. Clin Cancer Res. 2016 07 15; 22(14):3593-605. PMID: 26927665; PMCID: PMC4947447.
      Citations: 17     Fields:    Translation:Humans
    169. Tang Z, Tang G, Wang SA, Lu X, Young KH, Bueso-Ramos CE, Alvarado Y, Medeiros LJ, Khoury JD. Simultaneous deletion of 3'ETV6 and 5'EWSR1 genes in blastic plasmacytoid dendritic cell neoplasm: case report and literature review. Mol Cytogenet. 2016; 9:23. PMID: 26925167; PMCID: PMC4769509.
      Citations: 6     
    170. Aye le L, Loghavi S, Young KH, Siddiqi I, Yin CC, Routbort MJ, Liang M, Eilerman K, Medeiros LJ, Brynes RK, Bueso-Ramos C. Preleukemic phase of chronic myelogenous leukemia: morphologic and immunohistochemical characterization of 7 cases. Ann Diagn Pathol. 2016 Apr; 21:53-8. PMID: 27040932.
      Citations: 3     Fields:    Translation:HumansCells
    171. Xu-Monette ZY, Zhang S, Li X, Manyam GC, Wang XX, Xia Y, Visco C, Tzankov A, Zhang L, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Zhao X, Parsons BM, Winter JN, Piris MA, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function. Aging (Albany NY). 2016 Feb; 8(2):345-65. PMID: 26878872; PMCID: PMC4789587.
      Citations: 14     Fields:    Translation:HumansCells
    172. Borges NM, do Vale Elias M, Fook-Alves VL, Andrade TA, de Conti ML, Macedo MP, Begnami MD, Campos AH, Etto LY, Bortoluzzo AB, Alves AC, Young KH, Colleoni GW. Angiomirs expression profiling in diffuse large B-Cell lymphoma. Oncotarget. 2016 Jan 26; 7(4):4806-16. PMID: 26683099; PMCID: PMC4826244.
      Citations:    
    173. Ye Q, Xu-Monette ZY, Tzankov A, Deng L, Wang X, Manyam GC, Visco C, Montes-Moreno S, Zhang L, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Parsons BM, Piris MA, Winter JN, Medeiros LJ, Hu S, Young KH, Dybk?r K, Ferreri AJ, M?ller MB. Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell lymphoma. Oncotarget. 2016 Jan 19; 7(3):2401-16. PMID: 26573234; PMCID: PMC4823044.
      Citations: 34     Fields:    Translation:Humans
    174. de Winde CM, Veenbergen S, Young KH, Xu-Monette ZY, Wang XX, Xia Y, Jabbar KJ, van den Brand M, van der Schaaf A, Elfrink S, van Houdt IS, Gijbels MJ, van de Loo FA, Bennink MB, Hebeda KM, Groenen PJ, van Krieken JH, Figdor CG, van Spriel AB. Tetraspanin CD37 protects against the development of B cell lymphoma. J Clin Invest. 2016 Feb; 126(2):653-66. PMID: 26784544; PMCID: PMC4731177.
      Citations: 21     Fields:    Translation:Animals
    175. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Akematsu T, Akporiaye ET, Al-Rubeai M, Albanese C, Albani D, Albert ML, Aldudo J, Alirezaei M, Alloza I, Almasan A, Alnemri ES, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bao H, Barrachina MD, Barreiro E, Bartel B, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beck GR, Beckham JD, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernassola F, Bertolotti A, Bess AS, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bingol B, Bird SW, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Bonaldo P, Bordi M, Boulton ME, Bouret SG, Bozhkov PV, Brady N, Braga VM, Brancolini C, Brennan LA, Bresnick EH, Brest P, Bridges D, Brini M, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burke RE, Burmeister M, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Campanella M, Campbell GR, Campbell M, Campello S, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carroll B, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Cervia D, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clarke PG, Clarke R, Clementi E, Cnop M, Cocco T, Cohen EE, Colecchia D, Coletto L, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652; PMCID: PMC4835977.
      Citations: 2567     Fields:    Translation:HumansAnimals
    176. Cao X, Medeiros LJ, Xia Y, Wang X, Thomas SK, Loghavi S, Li X, Shah JJ, Gustafson SA, Weber DM, Miranda RN, Xu-Monette ZY, Orlowski RZ, Young KH. Clinicopathologic features and outcomes of lymphoplasmacytic lymphoma patients with monoclonal IgG or IgA paraprotein expression. Leuk Lymphoma. 2016 May; 57(5):1104-13. PMID: 26421453.
      Citations: 10     Fields:    Translation:Humans
    177. Yabe M, Medeiros LJ, Tang G, Wang SA, P Patel K, Routbort M, Bhagat G, Bueso-Ramos CE, Jorgensen JL, Luthra R, Chen W, Muzzafar T, Kanagal-Shamanna R, Khoury JD, Daneshbod Y, Davanlou M, Li S, Young KH, Miranda RN. Dyspoietic changes associated with hepatosplenic T-cell lymphoma are not a manifestation of a myelodysplastic syndrome: analysis of 25 patients. Hum Pathol. 2016 Apr; 50:109-17. PMID: 26997444.
      Citations: 1     Fields:    Translation:HumansCells
    178. Wang X, Huang H, Young KH. The PTEN tumor suppressor gene and its role in lymphoma pathogenesis. Aging (Albany NY). 2015 Dec; 7(12):1032-49. PMID: 26655726; PMCID: PMC4712330.
      Citations: 26     Fields:    Translation:Humans
    179. Clemens MW, Medeiros LJ, Butler CE, Hunt KK, Fanale MA, Horwitz S, Weisenburger DD, Liu J, Morgan EA, Kanagal-Shamanna R, Parkash V, Ning J, Sohani AR, Ferry JA, Mehta-Shah N, Dogan A, Liu H, Thormann N, Di Napoli A, DiNapoli A, Lade S, Piccolini J, Reyes R, Williams T, McCarthy CM, Hanson SE, Nastoupil LJ, Gaur R, Oki Y, Young KH, Miranda RN. Complete Surgical Excision Is Essential for the Management of Patients With Breast Implant-Associated Anaplastic Large-Cell Lymphoma. J Clin Oncol. 2016 Jan 10; 34(2):160-8. PMID: 26628470; PMCID: PMC4872006.
      Citations: 86     Fields:    Translation:Humans
    180. Wang ML, Lee H, Chuang H, Wagner-Bartak N, Hagemeister F, Westin J, Fayad L, Samaniego F, Turturro F, Oki Y, Chen W, Badillo M, Nomie K, DeLa Rosa M, Zhao D, Lam L, Addison A, Zhang H, Young KH, Li S, Santos D, Medeiros LJ, Champlin R, Romaguera J, Zhang L. Ibrutinib in combination with rituximab in relapsed or refractory mantle cell lymphoma: a single-centre, open-label, phase 2 trial. Lancet Oncol. 2016 Jan; 17(1):48-56. PMID: 26640039.
      Citations: 65     Fields:    Translation:HumansCTClinical Trials
    181. Xia Y, Medeiros LJ, Young KH. Immune checkpoint blockade: Releasing the brake towards hematological malignancies. Blood Rev. 2016 05; 30(3):189-200. PMID: 26699946.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    182. Cai Q, Medeiros LJ, Xu X, Young KH. MYC-driven aggressive B-cell lymphomas: biology, entity, differential diagnosis and clinical management. Oncotarget. 2015 Nov 17; 6(36):38591-616. PMID: 26416427; PMCID: PMC4770723.
      Citations: 18     Fields:    Translation:HumansAnimals
    183. Xu-Monette ZY, Dabaja BS, Wang X, Tu M, Manyam GC, Tzankov A, Xia Y, Zhang L, Sun R, Visco C, Dybkaer K, Yin L, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Parsons BM, Zhao X, Winter JN, McDonnell TJ, Miranda RN, Li Y, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB, Piris MA. Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Mod Pathol. 2015 Dec; 28(12):1555-73. PMID: 26541272.
      Citations: 21     Fields:    Translation:HumansCells
    184. Xia Y, Jeffrey Medeiros L, Young KH. Signaling pathway and dysregulation of PD1 and its ligands in lymphoid malignancies. Biochim Biophys Acta. 2016 Jan; 1865(1):58-71. PMID: 26432723; PMCID: PMC4733614.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    185. Yabe M, Medeiros LJ, Wang SA, Konoplev S, Ok CY, Loghavi S, Lu G, Flores L, Khoury JD, Cason RC, Young KH, Miranda RN. Clinicopathologic, Immunophenotypic, Cytogenetic, and Molecular Features of ?d T-Cell Large Granular Lymphocytic Leukemia: An Analysis of 14 Patients Suggests Biologic Differences With a? T-Cell Large Granular Lymphocytic Leukemia. [corrected]. Am J Clin Pathol. 2015 Oct; 144(4):607-19. PMID: 26386082.
      Citations: 11     Fields:    Translation:Humans
    186. Deng L, Song Y, Young KH, Hu S, Ding N, Song W, Li X, Shi Y, Huang H, Liu W, Zheng W, Wang X, Xie Y, Lin N, Tu M, Ping L, Ying Z, Zhang C, Sun Y, Zhu J. Hepatitis B virus-associated diffuse large B-cell lymphoma: unique clinical features, poor outcome, and hepatitis B surface antigen-driven origin. Oncotarget. 2015 Sep 22; 6(28):25061-73. PMID: 26314957; PMCID: PMC4694815.
      Citations: 24     Fields:    Translation:HumansCells
    187. Li L, Xu-Monette ZY, Ok CY, Tzankov A, Manyam GC, Sun R, Visco C, Zhang M, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Wang J, Parsons BM, Winter JN, Piris MA, Pham LV, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma. Oncotarget. 2015 Sep 15; 6(27):23157-80. PMID: 26324762; PMCID: PMC4695110.
      Citations: 21     Fields:    Translation:HumansCells
    188. Kanagal-Shamanna R, Xu-Monette ZY, Miranda RN, Dogan A, Zou D, Luthra R, Weber DM, O'Malley DP, Jorgensen JL, Khoury JD, Bueso-Ramos CE, Orlowski RZ, Medeiros LJ, Young KH. Crystal-storing histiocytosis: a clinicopathological study of 13 cases. Histopathology. 2016 Mar; 68(4):482-91. PMID: 26118455; PMCID: PMC4704983.
      Citations: 20     Fields:    Translation:HumansCells
    189. Lu TX, Young KH, Xu W, Li JY. TP53 dysfunction in diffuse large B-cell lymphoma. Crit Rev Oncol Hematol. 2016 Jan; 97:47-55. PMID: 26315382.
      Citations: 16     Fields:    Translation:HumansCells
    190. Liu Z, Xu-Monette ZY, Cao X, Manyam GC, Wang X, Tzankov A, Xia Y, Li X, Visco C, Sun R, Zhang L, Montes-Moreno S, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Parsons BM, Piris MA, Winter JN, O'Malley DP, Medeiros LJ, Young KH, Dybk?r K, Ferreri AJ, M?ller MB. Prognostic and biological significance of survivin expression in patients with diffuse large B-cell lymphoma treated with rituximab-CHOP therapy. Mod Pathol. 2015 Oct; 28(10):1297-314. PMID: 26248897.
      Citations: 9     Fields:    Translation:HumansCells
    191. Wang W, Hu S, Lu X, Young KH, Medeiros LJ. Triple-hit B-cell Lymphoma With MYC, BCL2, and BCL6 Translocations/Rearrangements: Clinicopathologic Features of 11 Cases. Am J Surg Pathol. 2015 Aug; 39(8):1132-9. PMID: 25828391.
      Citations: 22     Fields:    Translation:Humans
    192. Visco C, Falisi E, Young KH, Pascarella M, Perbellini O, Carli G, Novella E, Rossi D, Giaretta I, Cavallini C, Scupoli MT, De Rossi A, D'Amore ES, Rassu M, Gaidano G, Pizzolo G, Ambrosetti A, Rodeghiero F. Epstein-Barr virus DNA load in chronic lymphocytic leukemia is an independent predictor of clinical course and survival. Oncotarget. 2015 Jul 30; 6(21):18653-63. PMID: 26087198; PMCID: PMC4621917.
      Citations: 9     Fields:    Translation:HumansCells
    193. Lu TX, Fan L, Wang L, Wu JZ, Miao KR, Liang JH, Gong QX, Wang Z, Young KH, Xu W, Zhang ZH, Li JY. MYC or BCL2 copy number aberration is a strong predictor of outcome in patients with diffuse large B-cell lymphoma. Oncotarget. 2015 Jul 30; 6(21):18374-88. PMID: 26158410; PMCID: PMC4621897.
      Citations: 20     Fields:    Translation:Humans
    194. Gilbert FJ, Tucker L, Gillan MG, Willsher P, Cooke J, Duncan KA, Michell MJ, Dobson HM, Lim YY, Suaris T, Astley SM, Morrish O, Young KC, Duffy SW. Accuracy of Digital Breast Tomosynthesis for Depicting Breast Cancer Subgroups in a UK Retrospective Reading Study (TOMMY Trial). Radiology. 2015 Dec; 277(3):697-706. PMID: 26176654.
      Citations: 43     Fields:    Translation:Humans
    195. Ok CY, Young KH. Age cutoff in lymphoma diagnosis. Aging (Albany NY). 2015 Jul; 7(7):451-2. PMID: 26187891; PMCID: PMC4543027.
      Citations:    Fields:    Translation:Humans
    196. Ok CY, Xu-Monette ZY, Li L, Manyam GC, Montes-Moreno S, Tzankov A, Visco C, Routbort MJ, Zhang L, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Parsons BM, Rao H, Winter JN, Piris MA, Wang SA, Medeiros LJ, Young KH, Dybk?r K, Ferreri AJ, M?ller MB. Evaluation of NF-?B subunit expression and signaling pathway activation demonstrates that p52 expression confers better outcome in germinal center B-cell-like diffuse large B-cell lymphoma in association with CD30 and BCL2 functions. Mod Pathol. 2015 Sep; 28(9):1202-13. PMID: 26111978.
      Citations: 11     Fields:    Translation:HumansCells
    197. Cao X, Ye Q, Orlowski RZ, Wang X, Loghavi S, Tu M, Thomas SK, Shan J, Li S, Qazilbash M, Yin CC, Weber D, Miranda RN, Xu-Monette ZY, Medeiros LJ, Young KH. Waldenstr?m macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis. J Hematol Oncol. 2015 Jun 24; 8:74. PMID: 26104577; PMCID: PMC4487966.
      Citations: 2     Fields:    Translation:Humans
    198. Ok CY, Ye Q, Li L, Manyam GC, Deng L, Goswami RR, Wang X, Montes-Moreno S, Visco C, Tzankov A, Dybkaer K, Zhang L, Abramson J, Sohani AR, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Zhang S, Parsons BM, Xu M, Winter JN, Piris MA, Xu-Monette ZY, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. Age cutoff for Epstein-Barr virus-positive diffuse large B-cell lymphoma--is it necessary? Oncotarget. 2015 Jun 10; 6(16):13933-45. PMID: 26101854; PMCID: PMC4546442.
      Citations: 15     Fields:    Translation:HumansAnimals
    199. Ma X, Conklin DJ, Li F, Dai Z, Hua X, Li Y, Xu-Monette ZY, Young KH, Xiong W, Wysoczynski M, Sithu SD, Srivastava S, Bhatnagar A, Li Y. The oncogenic microRNA miR-21 promotes regulated necrosis in mice. Nat Commun. 2015 May 20; 6:7151. PMID: 25990308; PMCID: PMC4440243.
      Citations: 43     Fields:    Translation:Animals
    200. Ok CY, Patel KP, Garcia-Manero G, Routbort MJ, Peng J, Tang G, Goswami M, Young KH, Singh R, Medeiros LJ, Kantarjian HM, Luthra R, Wang SA. TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases. J Hematol Oncol. 2015 May 08; 8:45. PMID: 25952993; PMCID: PMC4431603.
      Citations: 42     Fields:    Translation:Humans
    201. Liu Z, Medeiros LJ, Young KH. Peripheral T-cell lymphoma with unusual clinical presentation of rhabdomyolysis. Hematol Oncol. 2017 Mar; 35(1):125-129. PMID: 25921311.
      Citations: 1     Fields:    Translation:Humans
    202. Falgreen S, Young KH, Xu-Monette ZY, El-Galaly TC, Laursen MB, Kjeldsen MK, Schmitz A, Nyegaard M, Johnsen HE, Dybk?r K, B?dker JS, B?gsted M. Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models. BMC Cancer. 2015 Apr 08; 15:235. PMID: 25881228; PMCID: PMC4396063.
      Citations: 28     Fields:    Translation:HumansCells
    203. Dybk?r K, B?gsted M, Falgreen S, B?dker JS, Kjeldsen MK, Schmitz A, Bilgrau AE, Xu-Monette ZY, Li L, Bergkvist KS, Laursen MB, Rodrigo-Domingo M, Marques SC, Rasmussen SB, Nyegaard M, Gaihede M, M?ller MB, Samworth RJ, Shah RD, Johansen P, El-Galaly TC, Young KH, Johnsen HE. Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis. J Clin Oncol. 2015 Apr 20; 33(12):1379-88. PMID: 25800755; PMCID: PMC4397280.
      Citations: 56     Fields:    Translation:HumansCells
    204. Chen J, Xu-Monette ZY, Deng L, Shen Q, Manyam GC, Martinez-Lopez A, Zhang L, Montes-Moreno S, Visco C, Tzankov A, Yin L, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Zhao X, Farnen JP, Winter JN, Piris MA, Pham L, Young KH, Ferreri AJ, M?ller MB. Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma. Oncotarget. 2015 Mar 20; 6(8):5597-614. PMID: 25704881; PMCID: PMC4467389.
      Citations: 36     Fields:    Translation:HumansCells
    205. Xu-Monette ZY, Tu M, Jabbar KJ, Cao X, Tzankov A, Visco C, Nagarajan L, Cai Q, Montes-Moreno S, An Y, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Zhao X, Farnen JP, Winter JN, Piris MA, Miranda RN, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. Clinical and biological significance of de novo CD5+ diffuse large B-cell lymphoma in Western countries. Oncotarget. 2015 Mar 20; 6(8):5615-33. PMID: 25760242; PMCID: PMC4467390.
      Citations: 23     Fields:    Translation:Humans
    206. Li Y, Hu S, Zuo Z, Hong M, Lin P, Li S, Konoplev S, Wang Z, Khoury JD, Young KH, Medeiros LJ, Yin CC. CD5-positive follicular lymphoma: clinicopathologic correlations and outcome in 88 cases. Mod Pathol. 2015 Jun; 28(6):787-98. PMID: 25743023.
      Citations: 8     Fields:    Translation:Humans
    207. Ok CY, Li L, Young KH. EBV-driven B-cell lymphoproliferative disorders: from biology, classification and differential diagnosis to clinical management. Exp Mol Med. 2015 Jan 23; 47:e132. PMID: 25613729; PMCID: PMC4314582.
      Citations: 33     Fields:    Translation:HumansCells
    208. Cai Q, Chen K, Young KH. Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorders. Exp Mol Med. 2015 Jan 23; 47:e133. PMID: 25613730; PMCID: PMC4314580.
      Citations: 20     Fields:    Translation:HumansCells
    209. Ok CY, Patel KP, Garcia-Manero G, Routbort MJ, Fu B, Tang G, Goswami M, Singh R, Kanagal-Shamanna R, Pierce SA, Young KH, Kantarjian HM, Medeiros LJ, Luthra R, Wang SA. Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases. Leuk Res. 2015 Mar; 39(3):348-54. PMID: 25573287; PMCID: PMC5548131.
      Citations: 43     Fields:    Translation:Humans
    210. Andrade TA, Evangelista AF, Campos AH, Poles WA, Borges NM, Camillo CM, Soares FA, Vassallo J, Paes RP, Zerbini MC, Scapulatempo C, Alves AC, Young KH, Colleoni GW. A microRNA signature profile in EBV+ diffuse large B-cell lymphoma of the elderly. Oncotarget. 2014 Dec 15; 5(23):11813-26. PMID: 25544772; PMCID: PMC4322989.
      Citations: 18     Fields:    Translation:HumansCells
    211. Yu H, Yue X, Zhao Y, Li X, Wu L, Zhang C, Liu Z, Lin K, Xu-Monette ZY, Young KH, Liu J, Shen Z, Feng Z, Hu W. LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers. Nat Commun. 2014 Oct 17; 5:5218. PMID: 25323535; PMCID: PMC4203416.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    212. Ok CY, Chen J, Xu-Monette ZY, Tzankov A, Manyam GC, Li L, Visco C, Montes-Moreno S, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Zhao X, Ponzoni M, Bertoni F, Farnen JP, Piris MA, Winter JN, Medeiros LJ, Young KH, Dybk?r K, Ferreri AJ, M?ller MB. Clinical implications of phosphorylated STAT3 expression in De Novo diffuse large B-cell lymphoma. Clin Cancer Res. 2014 Oct 01; 20(19):5113-23. PMID: 25124685; PMCID: PMC4184926.
      Citations: 33     Fields:    Translation:HumansCells
    213. Adrada BE, Miranda RN, Rauch GM, Arribas E, Kanagal-Shamanna R, Clemens MW, Fanale M, Haideri N, Mustafa E, Larrinaga J, Reisman NR, Jaso J, You MJ, Young KH, Medeiros LJ, Yang W. Breast implant-associated anaplastic large cell lymphoma: sensitivity, specificity, and findings of imaging studies in 44 patients. Breast Cancer Res Treat. 2014 Aug; 147(1):1-14. PMID: 25073777.
      Citations: 33     Fields:    Translation:Humans
    214. Zhang LN, Wang L, Fang C, Zou ZJ, Fan L, Zhang R, Young KH, Li JY, Xu W. The significance of single nucleotide polymorphism rs2070770 in CD20 gene in Chinese patients with diffuse large B-cell lymphoma. Leuk Lymphoma. 2015 Mar; 56(3):676-81. PMID: 24898664.
      Citations: 2     Fields:    Translation:Humans
    215. Han L, Zhang M, Li L, Zhang L, Wu J, Li X, Wang X, Young KH, Fu X, Ma W, Sun Z, Zhang X, Chang Y, Qiao Z. Natural killer/T-cell lymphoma-associated hemophagocytic syndrome: A case report. Oncol Lett. 2014 Aug; 8(2):886-890. PMID: 25013513; PMCID: PMC4081409.
      Citations:    
    216. Liu J, Zhang C, Lin M, Zhu W, Liang Y, Hong X, Zhao Y, Young KH, Hu W, Feng Z. Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma. Oncotarget. 2014 May 15; 5(9):2635-47. PMID: 24797434; PMCID: PMC4058033.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    217. Kong G, Wunderlich M, Yang D, Ranheim EA, Young KH, Wang J, Chang YI, Du J, Liu Y, Tey SR, Zhang X, Juckett M, Mattison R, Damnernsawad A, Zhang J, Mulloy JC, Zhang J. Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm. J Clin Invest. 2014 Jun; 124(6):2762-73. PMID: 24812670; PMCID: PMC4038579.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    218. Gordon MW, Yan F, Zhong X, Mazumder PB, Xu-Monette ZY, Zou D, Young KH, Ramos KS, Li Y. Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. Mol Carcinog. 2015 Oct; 54(10):1060-9. PMID: 24798859; PMCID: PMC4223015.
      Citations: 24     Fields:    Translation:HumansCells
    219. Cai Q, Luo X, Zhang G, Huang H, Huang H, Lin T, Jiang W, Xia Z, Young KH. New prognostic model for extranodal natural killer/T cell lymphoma, nasal type. Ann Hematol. 2014 Sep; 93(9):1541-9. PMID: 24782120.
      Citations: 14     Fields:    Translation:Humans
    220. Wang S, Medeiros LJ, Xu-Monette ZY, Zhang S, O'Malley DP, Orazi A, Zuo Z, Bueso-Ramos CE, Yin CC, Liu Z, Miranda RN, Young KH. Epstein-Barr virus-positive nodular lymphocyte predominant Hodgkin lymphoma. Ann Diagn Pathol. 2014 Aug; 18(4):203-9. PMID: 24852241.
      Citations: 9     Fields:    Translation:Humans
    221. Chang YI, Damnernsawad A, Allen LK, Yang D, Ranheim EA, Young KH, Zhang J, Kong G, Wang J, Liu Y, Fu HY, Yang CS, Guo J, Song H, Zhang J. Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation. Br J Haematol. 2014 Aug; 166(3):461-5. PMID: 24697267; PMCID: PMC4107140.
      Citations: 9     Fields:    Translation:Humans
    222. Sotomayor EM, Young KH, Younes A. Clinical roundtable monograph: CD30 in lymphoma: its role in biology, diagnostic testing, and targeted therapy. Clin Adv Hematol Oncol. 2014 Apr; 12(4 Suppl 10):1-22. PMID: 24870054.
      Citations: 3     Fields:    Translation:Humans
    223. Ok CY, Xu-Monette ZY, Tzankov A, O'Malley DP, Montes-Moreno S, Visco C, Dybkaer K, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Han van Krieken J, Ponzoni M, Farnen JP, Piris MA, Winter JN, Medeiros LJ, Young KH, M?ller MB. Prevalence and clinical implications of cyclin D1 expression in diffuse large B-cell lymphoma (DLBCL) treated with immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program. Cancer. 2014 Jun 15; 120(12):1818-29. PMID: 24648050.
      Citations: 13     Fields:    Translation:HumansAnimals
    224. Wang SA, Hasserjian RP, Fox PS, Rogers HJ, Geyer JT, Chabot-Richards D, Weinzierl E, Hatem J, Jaso J, Kanagal-Shamanna R, Stingo FC, Patel KP, Mehrotra M, Bueso-Ramos C, Young KH, Dinardo CD, Verstovsek S, Tiu RV, Bagg A, Hsi ED, Arber DA, Foucar K, Luthra R, Orazi A. Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms. Blood. 2014 Apr 24; 123(17):2645-51. PMID: 24627528; PMCID: PMC4067498.
      Citations: 61     Fields:    Translation:HumansCells
    225. Odqvist L, Montes-Moreno S, Young KH, Cereceda L, Pajares R, Mollejo M, Fresno MF, Mazorra F, Piris MA, S?nchez-Pacheco RE, Mart?n-S?nchez E, S?nchez-Verde L, Ru?z-Marcell?n C, S?nchez-Beato M. NF?B expression is a feature of both activated B-cell-like and germinal center B-cell-like subtypes of diffuse large B-cell lymphoma. Mod Pathol. 2014 Oct; 27(10):1331-7. PMID: 24603590.
      Citations: 20     Fields:    Translation:Humans
    226. Ok CY, Li L, Xu-Monette ZY, Visco C, Tzankov A, Manyam GC, Montes-Moreno S, Dybkaer K, Dybaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Chen J, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ai W, Ponzoni M, Farnen JP, Bueso-Ramos CE, Miranda RN, Winter JN, Piris MA, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. Prevalence and clinical implications of epstein-barr virus infection in de novo diffuse large B-cell lymphoma in Western countries. Clin Cancer Res. 2014 May 01; 20(9):2338-49. PMID: 24583797; PMCID: PMC4014309.
      Citations: 51     Fields:    Translation:HumansCells
    227. Tzankov A, Xu-Monette ZY, Gerhard M, Visco C, Dirnhofer S, Gisin N, Dybkaer K, Orazi A, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Ponzoni M, Ye Q, Winter JN, Farnen JP, You MJ, McDonnell T, Medeiros LJ, Young KH, Ferreri AJ, Piris MA, M?ller MB. Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Mod Pathol. 2014 Jul; 27(7):958-71. PMID: 24336156.
      Citations: 48     Fields:    Translation:Humans
    228. Miranda RN, Aladily TN, Prince HM, Kanagal-Shamanna R, de Jong D, Fayad LE, Amin MB, Haideri N, Bhagat G, Brooks GS, Shifrin DA, O'Malley DP, Cheah CY, Bacchi CE, Gualco G, Li S, Keech JA, Hochberg EP, Carty MJ, Hanson SE, Mustafa E, Sanchez S, Manning JT, Xu-Monette ZY, Miranda AR, Fox P, Bassett RL, Castillo JJ, Beltran BE, de Boer JP, Chakhachiro Z, Ye D, Clark D, Young KH, Medeiros LJ. Breast implant-associated anaplastic large-cell lymphoma: long-term follow-up of 60 patients. J Clin Oncol. 2014 Jan 10; 32(2):114-20. PMID: 24323027; PMCID: PMC4062709.
      Citations: 96     Fields:    Translation:Humans
    229. Jain P, Young KH. Haematological cancer: Richter's transformation in CLL-a distinct lymphoma. Nat Rev Clin Oncol. 2014 Jan; 11(1):6-8. PMID: 24281057.
      Citations:    Fields:    Translation:HumansCells
    230. Chou FP, Chen YW, Zhao XF, Xu-Monette ZY, Young KH, Gartenhaus RB, Wang JK, Kataoka H, Zuo AH, Barndt RJ, Johnson M, Lin CY. Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas. Am J Pathol. 2013 Oct; 183(4):1306-17. PMID: 24070417; PMCID: PMC3791685.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    231. Wang S, Tzankov A, Xu-Monette ZY, Hoeller S, Wang SA, Richards KL, Zhang S, Said JW, Medeiros LJ, Young KH. Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications. Hum Pathol. 2013 Dec; 44(12):2658-67. PMID: 24071012.
      Citations: 5     Fields:    Translation:Humans
    232. Chigrinova E, Rinaldi A, Kwee I, Rossi D, Rancoita PM, Strefford JC, Oscier D, Stamatopoulos K, Papadaki T, Berger F, Young KH, Murray F, Rosenquist R, Greiner TC, Chan WC, Orlandi EM, Lucioni M, Marasca R, Inghirami G, Ladetto M, Forconi F, Cogliatti S, Votavova H, Swerdlow SH, Stilgenbauer S, Piris MA, Matolcsy A, Spagnolo D, Nikitin E, Gattei V, Bhagat G, Ott G, Zucca E, Gaidano G, Bertoni F, Zam? A. Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome. Blood. 2013 Oct 10; 122(15):2673-82. PMID: 24004666.
      Citations: 66     Fields:    Translation:HumansCells
    233. Boi M, Rinaldi A, Kwee I, Bonetti P, Todaro M, Piva R, Rancoita PM, Timar B, Tousseyn T, Piris MA, Campo E, Bhagat G, Swerdlow SH, Rosenwald A, Ponzoni M, Young KH, Piccaluga PP, Dummer R, Pileri S, Zucca E, Inghirami G, Bertoni F, Tabb? F, Matolcsy A, Rodr?guez-Pinilla SM, Be? S. PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma. Blood. 2013 Oct 10; 122(15):2683-93. PMID: 24004669.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    234. Li S, Lin P, Young KH, Kanagal-Shamanna R, Yin CC, Medeiros LJ. MYC/BCL2 double-hit high-grade B-cell lymphoma. Adv Anat Pathol. 2013 Sep; 20(5):315-26. PMID: 23939148.
      Citations: 27     Fields:    Translation:Humans
    235. Xu-Monette ZY, Tzankov A, Montes-Moreno S, Hu W, Manyam GC, Kristensen L, Fan L, Visco C, Dybkaer K, Chiu A, Tam W, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huang Q, Huh J, Ai W, Ponzoni M, Wu L, Zhao X, Bueso-Ramos CE, Wang SA, Go RS, Li Y, Winter JN, Piris MA, Medeiros LJ, Young KH, M?ller MB, Ferreri AJ. MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 Oct 10; 122(15):2630-40. PMID: 23982177; PMCID: PMC3952598.
      Citations: 25     Fields:    Translation:Humans
    236. Zhu H, Wu W, Fu Y, Shen W, Miao K, Hong M, Xu W, Young KH, Liu P, Li J. Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia. Ann Hematol. 2014 Mar; 93(3):425-35. PMID: 23978946.
      Citations: 12     Fields:    Translation:HumansCells
    237. Zheng W, Medeiros LJ, Young KH, Goswami M, Powers L, Kantarjian HH, Thomas DA, Cortes JE, Wang SA. CD30 expression in acute lymphoblastic leukemia as assessed by flow cytometry analysis. Leuk Lymphoma. 2014 Mar; 55(3):624-7. PMID: 23937105; PMCID: PMC4188389.
      Citations: 12     Fields:    Translation:Humans
    238. Loo EY, Medeiros LJ, Aladily TN, Hoehn D, Kanagal-Shamanna R, Young KH, Lin P, Bueso-Ramos CE, Manning JT, Patel K, Thomazy V, Brynes RK, Goswami M, Fayad LE, Miranda RN. Classical Hodgkin lymphoma arising in the setting of iatrogenic immunodeficiency: a clinicopathologic study of 10 cases. Am J Surg Pathol. 2013 Aug; 37(8):1290-7. PMID: 23774171.
      Citations: 14     Fields:    Translation:HumansCells
    239. Jain P, Le X, Young KH, Patel KP, Wang S, Pei L, Barron LL, Abruzzo L, O'Brien S. Sequential lymphomas or clonally unrelated richter syndrome of chronic lymphocytic leukemia into mantle cell lymphoma. Clin Lymphoma Myeloma Leuk. 2013 Oct; 13(5):606-9. PMID: 23763914.
      Citations:    Fields:    Translation:Humans
    240. Jain P, Fayad LE, Rosenwald A, Young KH, O'Brien S. Recent advances in de novo CD5+ diffuse large B cell lymphoma. Am J Hematol. 2013 Sep; 88(9):798-802. PMID: 23695956.
      Citations: 28     Fields:    Translation:HumansCells
    241. Rinaldi A, Kwee I, Young KH, Zucca E, Gaidano G, Forconi F, Bertoni F. Genome-wide high resolution DNA profiling of hairy cell leukaemia. Br J Haematol. 2013 Aug; 162(4):566-9. PMID: 23692203.
      Citations: 13     Fields:    Translation:HumansCells
    242. Ok CY, Papathomas TG, Medeiros LJ, Young KH. EBV-positive diffuse large B-cell lymphoma of the elderly. Blood. 2013 Jul 18; 122(3):328-40. PMID: 23649469; PMCID: PMC3779382.
      Citations: 68     Fields:    Translation:HumansCells
    243. Li Y, Gordon MW, Xu-Monette ZY, Visco C, Tzankov A, Zou D, Qiu L, Montes-Moreno S, Dybkaer K, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huang Q, Ai W, Ponzoni M, Winter JN, Go RS, Piris MA, Wu L, Wang M, Ramos KS, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 May 30; 121(22):4529-40. PMID: 23515929; PMCID: PMC3668486.
      Citations: 16     Fields:    Translation:HumansCells
    244. Hu S, Xu-Monette ZY, Tzankov A, Green T, Wu L, Balasubramanyam A, Liu WM, Visco C, Li Y, Miranda RN, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, Zhao X, van Krieken JH, Huang Q, Huh J, Ai W, Ponzoni M, Zhou F, Slack GW, Gascoyne RD, Tu M, Variakojis D, Chen W, Go RS, Piris MA, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 May 16; 121(20):4021-31; quiz 4250. PMID: 23449635; PMCID: PMC3709650.
      Citations: 249     Fields:    Translation:HumansCells
    245. Hu S, Xu-Monette ZY, Balasubramanyam A, Manyam GC, Visco C, Tzankov A, Liu WM, Miranda RN, Zhang L, Montes-Moreno S, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, Han van Krieken J, Huang Q, Huh J, Ai W, Ponzoni M, Zhao X, Winter JN, Zhang M, Li L, Piris MA, Li Y, Go RS, Wu L, Medeiros LJ, Young KH, Dybk?r K, Ferreri AJ, M?ller MB. CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program Study. Blood. 2013 Apr 04; 121(14):2715-24. PMID: 23343832; PMCID: PMC3700465.
      Citations: 64     Fields:    Translation:HumansCells
    246. Hu S, Young KH, Konoplev SN, Medeiros LJ. Follicular T-cell lymphoma: a member of an emerging family of follicular helper T-cell derived T-cell lymphomas. Hum Pathol. 2012 Nov; 43(11):1789-98. PMID: 22959759.
      Citations: 8     Fields:    Translation:HumansCells
    247. Xu-Monette ZY, Wu L, Visco C, Tai YC, Tzankov A, Liu WM, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Zhao XF, Choi WW, Zhao X, van Krieken JH, Huang Q, Huh J, Ai W, Ponzoni M, Zhou F, Kahl BS, Winter JN, Xu W, Li J, Go RS, Li Y, Piris MA, Miranda RN, Abruzzo LV, Medeiros LJ, Young KH, Ferreri AJ, M?ller MB. Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program Study. Blood. 2012 Nov 08; 120(19):3986-96. PMID: 22955915; PMCID: PMC3496956.
      Citations: 141     Fields:    Translation:Humans
    248. Hoeller S, Zhou Y, Kanagal-Shamanna R, Xu-Monette ZY, Hoehn D, Bihl M, Swerdlow SH, Rosenwald A, Ott G, Said J, Dunphy CH, Bueso-Ramos CE, Lin P, Wang M, Miranda RN, Tzankov A, Medeiros LJ, Young KH. Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study. Hum Pathol. 2013 Jan; 44(1):110-21. PMID: 22944294; PMCID: PMC3640316.
      Citations: 9     Fields:    Translation:Humans
    249. Visco C, Tzankov A, Xu-Monette ZY, Miranda RN, Tai YC, Li Y, Liu WM, d'Amore ES, Li Y, Montes-Moreno S, Chiu A, Orazi A, Zu Y, Bhagat G, Wang HY, Dunphy CH, His ED, Zhao XF, Choi WW, Zhao X, van Krieken JH, Huang Q, Ai W, O'Neill S, Ponzoni M, Ferreri AJ, Kahl BS, Winter JN, Go RS, Dirnhofer S, Piris MA, Wu L, Medeiros LJ, Young KH, Dybk?r K, M?ller MB. Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an International DLBCL rituximab-CHOP Consortium Program Study. Haematologica. 2013 Feb; 98(2):255-63. PMID: 22929980; PMCID: PMC3561433.
      Citations: 64     Fields:    Translation:HumansCells
    250. Takwi AA, Li Y, Becker Buscaglia LE, Zhang J, Choudhury S, Park AK, Liu M, Young KH, Park WY, Martin RC, Li Y. A statin-regulated microRNA represses human c-Myc expression and function. EMBO Mol Med. 2012 Sep; 4(9):896-909. PMID: 22887866; PMCID: PMC3491823.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    251. Kanagal-Shamanna R, Medeiros LJ, Lu G, Wang SA, Manning JT, Lin P, Penn GM, Young KH, You MJ, Vega F, Bassett R, Miranda RN. High-grade B cell lymphoma, unclassifiable, with blastoid features: an unusual morphological subgroup associated frequently with BCL2 and/or MYC gene rearrangements and a poor prognosis. Histopathology. 2012 Nov; 61(5):945-54. PMID: 22804688.
      Citations: 6     Fields:    Translation:Humans
    252. Aladily TN, Medeiros LJ, Amin MB, Haideri N, Ye D, Azevedo SJ, Jorgensen JL, de Peralta-Venturina M, Mustafa EB, Young KH, You MJ, Fayad LE, Blenc AM, Miranda RN. Anaplastic large cell lymphoma associated with breast implants: a report of 13 cases. Am J Surg Pathol. 2012 Jul; 36(7):1000-8. PMID: 22613996.
      Citations: 40     Fields:    Translation:Humans
    253. Wang M, Fayad L, Wagner-Bartak N, Zhang L, Hagemeister F, Neelapu SS, Samaniego F, McLaughlin P, Fanale M, Younes A, Cabanillas F, Fowler N, Newberry KJ, Sun L, Young KH, Champlin R, Kwak L, Feng L, Badillo M, Bejarano M, Hartig K, Chen W, Chen Y, Byrne C, Bell N, Zeldis J, Romaguera J. Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial. Lancet Oncol. 2012 Jul; 13(7):716-23. PMID: 22677155.
      Citations: 89     Fields:    Translation:HumansCTClinical Trials
    254. Young KH, Visco C, Xu-Monette ZY, Orazi A, Go RS, Nielsen O, Gadeberg OV, Mourits-Andersen T, Frederiksen M, Green TM, Pedersen LM, M?ller MB. Immunohistochemical double-hit score is a strong predictor of outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol. 2012 Oct 01; 30(28):3460-7. PMID: 22665537.
      Citations: 239     Fields:    Translation:Humans
    255. Zhou Y, You MJ, Young KH, Lin P, Lu G, Medeiros LJ, Bueso-Ramos CE. Advances in the molecular pathobiology of B-lymphoblastic leukemia. Hum Pathol. 2012 Sep; 43(9):1347-62. PMID: 22575265.
      Citations: 25     Fields:    Translation:HumansCells
    256. Odqvist L, Diaz-Perez JA, Lopez AB, Mazorra F, Castillo ME, Lopez M, Pajares R, Mollejo M, Camacho FI, Adrados M, Ortiz N, Franco R, Ortiz-Hidalgo C, Suarez-Gauthier A, Young KH, Piris MA, Montes-Moreno S, de Villambros?a SG, Garc?a JF, Ruiz-Marcell?n C. EBV-positive diffuse large B-cell lymphoma of the elderly is an aggressive post-germinal center B-cell neoplasm characterized by prominent nuclear factor-kB activation. Mod Pathol. 2012 Jul; 25(7):968-82. PMID: 22538516.
      Citations: 59     Fields:    Translation:Humans
    257. Xu-Monette ZY, Young KH. The TP53 tumor suppressor and autophagy in malignant lymphoma. Autophagy. 2012 May 01; 8(5):842-5. PMID: 22498492; PMCID: PMC3378422.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    258. Green TM, Nielsen O, de Stricker K, Xu-Monette ZY, Young KH, M?ller MB. High levels of nuclear MYC protein predict the presence of MYC rearrangement in diffuse large B-cell lymphoma. Am J Surg Pathol. 2012 Apr; 36(4):612-9. PMID: 22314191.
      Citations: 32     Fields:    Translation:HumansCells
    259. Xu-Monette ZY, Medeiros LJ, Li Y, Orlowski RZ, Andreeff M, Bueso-Ramos CE, Greiner TC, McDonnell TJ, Young KH. Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies. Blood. 2012 Apr 19; 119(16):3668-83. PMID: 22275381; PMCID: PMC3335376.
      Citations: 65     Fields:    Translation:HumansCells
    260. Papathomas TG, Venizelos I, Dunphy CH, Said JW, Wang ML, Campo E, Swerdlow SH, Chan JC, Bueso-Ramos CE, Weisenburger DD, Medeiros LJ, Young KH. Mantle cell lymphoma as a component of composite lymphoma: clinicopathologic parameters and biologic implications. Hum Pathol. 2012 Apr; 43(4):467-80. PMID: 22221705.
      Citations:    Fields:    Translation:Humans
    261. Young KA, Fingerlin TE, Langefeld CD, Lorenzo C, Haffner SM, Wagenknecht LE, Norris JM. Exploring differences in adiposity in two U.S. Hispanic populations of Mexican origin using social, behavioral, physiologic and genetic markers: the IRAS Family Study. Ethn Dis. 2012; 22(1):65-71. PMID: 22774311; PMCID: PMC4020784.
      Citations: 3     Fields:    Translation:Humans
    262. Zhang J, Guy MJ, Norman HS, Chen YC, Xu Q, Dong X, Guner H, Wang S, Kohmoto T, Young KH, Moss RL, Ge Y. Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. J Proteome Res. 2011 Sep 02; 10(9):4054-65. PMID: 21751783; PMCID: PMC3170873.
      Citations: 89     Fields:    Translation:HumansCells
    263. Montes-Moreno S, Martinez N, Rodriguez ME, Saez A, Gomez G, Pisano DG, Conde E, Gonzalez-Barca E, Lopez A, Mollejo M, Grande C, Martinez MA, Dunphy C, Hsi ED, Rocque GB, Chang J, Go RS, Visco C, Xu-Monette Z, Young KH, Piris MA, Sanchez-Espiridi?n B, D?az Uriarte R, Montalb?n C, Garc?a JF. miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy. Blood. 2011 Jul 28; 118(4):1034-40. PMID: 21633089.
      Citations: 36     Fields:    Translation:Humans
    264. Wang J, Liu Y, Li Z, Wang Z, Tan LX, Ryu MJ, Meline B, Du J, Young KH, Ranheim E, Chang Q, Zhang J. Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner. Blood. 2011 Jul 14; 118(2):368-79. PMID: 21586752; PMCID: PMC3138689.
      Citations: 56     Fields:    Translation:HumansAnimals
    265. Visco C, Hoeller S, Malik JT, Xu-Monette ZY, Wiggins ML, Liu J, Sanger WG, Liu Z, Chang J, Ranheim EA, Gradowski JF, Serrano S, Wang HY, Liu Q, Dave S, Olsen B, Gascoyne RD, Campo E, Swerdlow SH, Chan WC, Tzankov A, Young KH. Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component. Am J Surg Pathol. 2011 Feb; 35(2):177-89. PMID: 21263238; PMCID: PMC3079277.
      Citations: 8     Fields:    Translation:HumansCells
    266. Rossi D, Spina V, Deambrogi C, Rasi S, Laurenti L, Stamatopoulos K, Arcaini L, Lucioni M, Rocque GB, Xu-Monette ZY, Visco C, Chang J, Chigrinova E, Forconi F, Marasca R, Besson C, Papadaki T, Paulli M, Larocca LM, Pileri SA, Gattei V, Bertoni F, Young KH, Gaidano G, Fo? R. The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation. Blood. 2011 Mar 24; 117(12):3391-401. PMID: 21266718.
      Citations: 95     Fields:    Translation:Humans
    267. Yang DT, Quann PJ, Petrich AM, Leith CP, Young KH, Kahl BS. Use of tissue microarray and automated quantitative analysis for screening and validation of potential biomarkers in mantle cell lymphoma. Appl Immunohistochem Mol Morphol. 2011 Jan; 19(1):62-9. PMID: 20881841; PMCID: PMC3040491.
      Citations: 3     Fields:    Translation:HumansAnimals
    268. Rasi S, Spina V, Bruscaggin A, Vaisitti T, Tripodo C, Forconi F, De Paoli L, Fangazio M, Sozzi E, Cencini E, Laurenti L, Marasca R, Visco C, Xu-Monette ZY, Gattei V, Young KH, Malavasi F, Deaglio S, Gaidano G, Rossi D. A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome. Br J Haematol. 2011 Feb; 152(3):284-94. PMID: 21121903.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    269. Lu Z, Li Y, Takwi A, Li B, Zhang J, Conklin DJ, Young KH, Martin R, Li Y. miR-301a as an NF-?B activator in pancreatic cancer cells. EMBO J. 2011 Jan 05; 30(1):57-67. PMID: 21113131; PMCID: PMC3020116.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    270. Ma SD, Hegde S, Young KH, Sullivan R, Rajesh D, Zhou Y, Jankowska-Gan E, Burlingham WJ, Sun X, Gulley ML, Tang W, Gumperz JE, Kenney SC. A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas. J Virol. 2011 Jan; 85(1):165-77. PMID: 20980506; PMCID: PMC3014199.
      Citations: 144     Fields:    Translation:HumansAnimalsCells
    271. Wang J, Liu Y, Li Z, Du J, Ryu MJ, Taylor PR, Fleming MD, Young KH, Pitot H, Zhang J. Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia. Blood. 2010 Dec 23; 116(26):5991-6002. PMID: 20921338; PMCID: PMC3031386.
      Citations: 71     Fields:    Translation:AnimalsCells
    272. Scandurra M, Mian M, Greiner TC, Rancoita PM, De Campos CP, Chan WC, Vose JM, Chigrinova E, Inghirami G, Chiappella A, Baldini L, Ponzoni M, Ferreri AJ, Franceschetti S, Gaidano G, Montes-Moreno S, Piris MA, Facchetti F, Tucci A, Nomdedeu JF, Lazure T, Lambotte O, Uccella S, Pinotti G, Pruneri G, Martinelli G, Young KH, Tibiletti MG, Rinaldi A, Zucca E, Kwee I, Bertoni F. Genomic lesions associated with a different clinical outcome in diffuse large B-Cell lymphoma treated with R-CHOP-21. Br J Haematol. 2010 Nov; 151(3):221-31. PMID: 20813005.
      Citations: 16     Fields:    Translation:HumansCells
    273. Chang H, Qi C, Trieu Y, Jiang A, Young KH, Chesney A, Jani P, Wang C, Reece D, Chen C. Prognostic relevance of 6q deletion in Waldenstr?m's macroglobulinemia: a multicenter study. Clin Lymphoma Myeloma. 2009 Mar; 9(1):36-8. PMID: 19362968.
      Citations: 5     Fields:    Translation:HumansCells
    274. Zhang J, Wang J, Liu Y, Sidik H, Young KH, Lodish HF, Fleming MD. Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation. Blood. 2009 Feb 05; 113(6):1304-14. PMID: 19066392; PMCID: PMC2637193.
      Citations: 50     Fields:    Translation:AnimalsCells
    275. d'Amore F, Chan E, Iqbal J, Geng H, Young K, Xiao L, Hess MM, Sanger WG, Smith L, Wiuf C, Hagberg O, Fu K, Chan WC, Dave BJ. Clonal evolution in t(14;18)-positive follicular lymphoma, evidence for multiple common pathways, and frequent parallel clonal evolution. Clin Cancer Res. 2008 Nov 15; 14(22):7180-7. PMID: 19010834.
      Citations: 16     Fields:    Translation:HumansCells
    276. Jones RJ, Chen Q, Voorhees PM, Young KH, Bruey-Sedano N, Yang D, Orlowski RZ. Inhibition of the p53 E3 ligase HDM-2 induces apoptosis and DNA damage--independent p53 phosphorylation in mantle cell lymphoma. Clin Cancer Res. 2008 Sep 01; 14(17):5416-25. PMID: 18765533; PMCID: PMC2576518.
      Citations: 13     Fields:    Translation:HumansCells
    277. Young KH, Leroy K, Colleoni GW, Haioun C, Eickhoff JC, Young AH, Gaulard P, Piris MA, Oberley TD, Rehrauer WM, Kahl BS, Malter JS, Campo E, Delabie J, Gascoyne RD, Rosenwald A, Rimsza L, Huang J, Braziel RM, Jaffe ES, Wilson WH, Staudt LM, Vose JM, Chan WC, Weisenburger DD, Greiner TC, M?ller MB, S?nchez-Beato M, Kerbauy FR. Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study. Blood. 2008 Oct 15; 112(8):3088-98. PMID: 18559976; PMCID: PMC2569165.
      Citations: 67     Fields:    Translation:Humans
    278. Yang DT, Young KH, Kahl BS, Markovina S, Miyamoto S. Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma. Mol Cancer. 2008 May 19; 7:40. PMID: 18489772; PMCID: PMC2408930.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    279. Young KH, Xie Q, Zhou G, Eickhoff JC, Sanger WG, Aoun P, Chan WC. Transformation of follicular lymphoma to precursor B-cell lymphoblastic lymphoma with c-myc gene rearrangement as a critical event. Am J Clin Pathol. 2008 Jan; 129(1):157-66. PMID: 18089500.
      Citations: 16     Fields:    Translation:HumansCells
    280. Young KH, Zhang D, Malik JT, Williams EC. Fulminant EBV-driven CD8 T-cell lymphoproliferative disorder following primary acute EBV infection: a unique spectrum of T-cell malignancy. Int J Clin Exp Pathol. 2008 Jan 01; 1(2):185-97. PMID: 18784807; PMCID: PMC2480557.
      Citations: 6     Fields:    
    281. Xie Q, Chen L, Fu K, Harter J, Young KH, Sunkara J, Novak D, Villanueva-Siles E, Ratech H. Podoplanin (d2-40): a new immunohistochemical marker for reactive follicular dendritic cells and follicular dendritic cell sarcomas. Int J Clin Exp Pathol. 2008 Jan 01; 1(3):276-84. PMID: 18784810; PMCID: PMC2480560.
      Citations: 14     Fields:    
    282. Young KA, Chen XS, Holers VM, Hannan JP. Isolating the Epstein-Barr virus gp350/220 binding site on complement receptor type 2 (CR2/CD21). J Biol Chem. 2007 Dec 14; 282(50):36614-25. PMID: 17925391.
      Citations: 11     Fields:    Translation:HumansCells
    283. Young KH, Weisenburger DD, Dave BJ, Smith L, Sanger W, Iqbal J, Campo E, Delabie J, Gascoyne RD, Ott G, Rimsza L, Jaffe ES, Rosenwald A, Staudt LM, Chan WC, Greiner TC, M?ller-Hermelink HK. Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma. Blood. 2007 Dec 15; 110(13):4396-405. PMID: 17881637; PMCID: PMC2234786.
      Citations: 33     Fields:    Translation:HumansCells
    284. Zhao XF, Young KH, Frank D, Goradia A, Glotzbecker MP, Pan W, Kersun LS, Leahey A, Dormans JP, Choi JK. Pediatric primary bone lymphoma-diffuse large B-cell lymphoma: morphologic and immunohistochemical characteristics of 10 cases. Am J Clin Pathol. 2007 Jan; 127(1):47-54. PMID: 17145622.
      Citations: 10     Fields:    Translation:Humans
    285. Young KH, Chan WC, Fu K, Iqbal J, Sanger WG, Ratashak A, Greiner TC, Weisenburger DD. Mantle cell lymphoma with plasma cell differentiation. Am J Surg Pathol. 2006 Aug; 30(8):954-61. PMID: 16861965.
      Citations: 11     Fields:    Translation:HumansCells
    286. Pirruccello SJ, Young KH, Aoun P. Myeloblast phenotypic changes in myelodysplasia. CD34 and CD117 expression abnormalities are common. Am J Clin Pathol. 2006 Jun; 125(6):884-94. PMID: 16690488.
      Citations: 4     Fields:    Translation:HumansCells
    287. Erratum. Leukemia. 28:980.
    288. Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Modern Pathology. 28:1555-1573.
    289. Clinical and biological significance of de novo CD5+ diffuse large B-cell lymphoma in Western countries. Oncotarget. 6:5615-5633.
    290. Hepatitis B virus-associated diffuse large B-cell lymphoma. Oncotarget. 6:25061-25075.
    291. Peripheral T-cell lymphoma with unusual clinical presentation of rhabdomyolysis. Hematological Oncology.
    292. Preleukemic phase of chronic myelogenous leukemia. Annals of Diagnostic Pathology. 21:53-58.
    293. TP53 dysfunction in diffuse large B-cell lymphoma. Critical Reviews in Oncology/Hematology. 97:47-55.
    294. Tetraspanin CD37 protects against the development of B cell lymphoma. Journal of Clinical Investigation. 126:653-666.
    295. TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases. Journal of Hematology and Oncology. 8.
    296. Waldenström macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis. Journal of Hematology and Oncology. 8.
    297. Clinicopathologic features and outcomes of lymphoplasmacytic lymphoma patients with monoclonal IgG or IgA paraprotein expression. Leukemia and Lymphoma. 1-10.
    298. Genetic lesions in diffuse large B-cell lymphomas. Annals of Oncology. 26:1069-1080.
    299. Loss of PRDM1/BLIMP-1 function contributes to poor prognosis of activated B-cell-like diffuse large B-cell lymphoma. Leukemia.
    300. Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma. Oncotarget. 6:5597-5614.
    301. Epstein-Barr virus DNA load in chronic lymphocytic leukemia is an independent predictor of clinical course and survival. Oncotarget. 6:18653-18663.
    302. Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms. Molecular Cytogenetics. 9.
    303. Primary testicular diffuse large B-cell lymphoma displays distinct clinical and biological features for treatment failure in rituximab era. Leukemia.
    304. MYC-driven aggressive B-cell lymphomas. Oncotarget. 6:38591-38616.
    305. LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers. Nature Communications. 5.
    306. MYC or BCL2 copy number aberration is a strong predictor of outcome in patients with diffuse large B-cell lymphoma. Oncotarget. 6:18374-18388.
    307. Immune checkpoint blockade. Blood Reviews.
    308. Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models. BMC Cancer. 15.
    309. p63 expression confers significantly better survival outcomes in highrisk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function. Aging. 8:345-365.
    310. Erratum to Clinical and biological significance of de novo CD5+ diffuse large B-cell lymphoma in Western countries [Oncotarget, 8, (2015), 5615-5633]. Oncotarget. 6:14720.
    311. Ibrutinib in combination with rituximab in relapsed or refractory mantle cell lymphoma. The Lancet Oncology.
    312. Role of programmed death ligands in effective T-cell interactions in extranodal natural killer/T-cell lymphoma. Oncology Letters. 8:1461-1469.
    313. Distinguishing Between Hepatosplenic T-cell Lymphoma and γδ T-cell Large Granular Lymphocytic Leukemia. American Journal of Surgical Pathology.
    314. Primary Cutaneous T-Cell Lymphomas Showing Gamma-Delta (γδ) Phenotype and Predominantly Epidermotropic Pattern are Clinicopathologically Distinct From Classic Primary Cutaneous γδ T-Cell Lymphomas. American Journal of Surgical Pathology.
    315. Simultaneous deletion of 3'ETV6 and 5' EWSR1 genes in blastic plasmacytoid dendritic cell neoplasm. Molecular Cytogenetics. 9.
    316. CD30 diagnostics and testing. Clinical Advances in Hematology and Oncology. 12:9-15.
    317. High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid. Oncotarget. 7:21631-21643.
    318. Age cutoff for Epstein-Barr virus-positive diffuse large B-cell lymphoma-is it necessary?. Oncotarget. 6:13933-13945.
    319. HemaClass.org. PLoS One. 11.
    320. Mantle Cell Lymphoma With MYC Rearrangement. American Journal of Surgical Pathology.
    321. Immunophenotypic and diagnostic characterization of angioimmunoblastic T-cell lymphoma by advanced flow cytometric technology. Leukemia and Lymphoma. 1-9.
    322. Angiomirs expression profiling in diffuse large B-Cell lymphoma. Oncotarget. 7:4806-4816.
    323. Natural killer/T-cell lymphoma-associated hemophagocytic syndrome. Oncology Letters. 8:886-890.
    324. Complete surgical excision is essential for the management of patients with breast implant-associated anaplastic large-cell lymphoma. Journal of Clinical Oncology. 34:160-168.
    325. The PTEN tumor suppressor gene and its role in lymphoma pathogenesis. Aging. 7:1032-1049.
    326. Reduced expression of TRIM21/Ro52 predicts poor prognosis in diffuse large B-cell lymphoma patients with and without rheumatic disease. Journal of Internal Medicine.
    327. Prognostic and biological significance of survivin expression in patients with diffuse large B-cell lymphoma treated with rituximab-CHOP therapy. Modern Pathology. 28:1297-1314.
    328. Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma. Oncotarget. 7:80599-80611.
    329. Age cutoff in lymphoma diagnosis. Aging. 7:451-452.
    330. Efficacy and safety of cisplatin, dexamethasone, gemcitabine and pegaspargase (DDGP) regimen in newly diagnosed, advanced-stage extranodal natural killer/T-cell lymphoma. Oncotarget. 7:55721-55731.
    331. Evaluation of NF-κB subunit expression and signaling pathway activation demonstrates that p52 expression confers better outcome in germinal center B-cell-like diffuse large B-cell lymphoma in association with CD30 and BCL2 functions. Modern Pathology. 28:1202-1213.
    332. Signaling pathway and dysregulation of PD1 and its ligands in lymphoid malignancies. Biochimica et Biophysica Acta - Reviews on Cancer. 1865:58-71.
    333. Hepatosplenic T-cell lymphoma arising in patients with immunodysregulatory disorders. Annals of Diagnostic Pathology. 26:16-22.
    334. Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine. Modern Pathology.
    335. Crystal-storing histiocytosis. Histopathology. 68:482-491.
    336. Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma. Oncotarget. 6:23157-23180.
    337. Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell lymphoma. Oncotarget. 7:2401-2416.
    338. Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy. Oncotarget. 7:18036-18049.
    339. NF-κB signaling pathway and its potential as a target for therapy in lymphoid neoplasms. Blood Reviews.
    340. Age cutoff for epstein-barr virus-positive diffuse large B-cell lymphoma - is it necessary?. Oncotarget. 6:13935-13946.
    341. The oncogenic microRNA miR-21 promotes regulated necrosis in mice. Nature Communications. 6.
    342. Clinical and biologic significance of MYC genetic mutations in de novo diffuse large B-cell lymphoma. Clinical Cancer Research. 22:3593-3605.
    YOUNG's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (783)
    Explore
    _
    Co-Authors (138)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _