TitleAssistant Professor
InstitutionMD Anderson
DepartmentClinical Cancer Prevention
Address6767 Bertner St
Houston TX 77030-2603
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhang KL, Shen QQ, Fang YF, Sun YM, Ding J, Chen Y. Author Correction: AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition. Acta Pharmacol Sin. 2020 05; 41(5):733-734. PMID: 32060412.
      Citations:    Fields:    
    2. Zhang SW, Gong CJ, Su MB, Chen F, He T, Zhang YM, Shen QQ, Su Y, Ding J, Li J, Chen Y, Nan FJ. Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors. J Med Chem. 2020 01 23; 63(2):804-815. PMID: 31855601.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Zhang KL, Shen QQ, Fang YF, Sun YM, Ding J, Chen Y. AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition. Acta Pharmacol Sin. 2019 Dec; 40(12):1587-1595. PMID: 31171828.
      Citations:    Fields:    Translation:HumansCells
    4. He PP, Shen QQ, Wen M, Zou JQ, Wang Y, Yang JX, Hu LZ, Zheng XL, Chen YS, Su H, Liu J, Ouyang XP, Tang CK. Nobiletin reduces LPL-mediated lipid accumulation and pro-in?ammatory cytokine secretion through upregulation of miR-590 expression. Biochem Biophys Res Commun. 2019 01 01; 508(1):97-101. PMID: 30471854.
      Citations: 4     Fields:    Translation:HumansCells
    5. Li D, Wang H, Ding Y, Zhang Z, Zheng Z, Dong J, Kim H, Meng X, Zhou Q, Zhou J, Fang L, Shen Q. Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis. Cancer Lett. 2018 06 28; 424:97-108. PMID: 29580806.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    6. Zhang Z, Zheng Z, Cai J, Liu Q, Yang J, Gong Y, Wu M, Shen Q, Xu S. Effect of cadmium on oxidative stress and immune function of common carp (Cyprinus carpio L.) by transcriptome analysis. Aquat Toxicol. 2017 Nov; 192:171-177. PMID: 28963925.
      Citations: 2     Fields:    Translation:AnimalsCells
    7. Zhang Z, Liu Q, Cai J, Yang J, Shen Q, Xu S. Chlorpyrifos exposure in common carp (Cyprinus carpio L.) leads to oxidative stress and immune responses. Fish Shellfish Immunol. 2017 Aug; 67:604-611. PMID: 28648885.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Yin Y, Shen Q, Zhang P, Tao R, Chang W, Li R, Xie G, Liu W, Zhang L, Kapoor P, Song S, Ajani J, Mills GB, Chen J, Tao K, Peng G. Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer. Am J Cancer Res. 2017; 7(3):473-483. PMID: 28401005.
    9. Wang T, Chang C, Gu C, Tang S, Xie Q, Shen QH. An E3 Ligase Affects the NLR Receptor Stability and Immunity to Powdery Mildew. Plant Physiol. 2016 12; 172(4):2504-2515. PMID: 27780896.
      Citations: 3     Fields:    Translation:AnimalsCells
    10. Sun SS, Zhou X, Huang YY, Kong LP, Mei M, Guo WY, Zhao MH, Ren Y, Shen Q, Zhang L. Targeting STAT3/miR-21 axis inhibits epithelial-mesenchymal transition via regulating CDK5 in head and neck squamous cell carcinoma. Mol Cancer. 2015 Dec 21; 14:213. PMID: 26690371.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    11. Jiang Z, Watts LT, Huang S, Shen Q, Rodriguez P, Chen C, Zhou C, Duong TQ. The Effects of Methylene Blue on Autophagy and Apoptosis in MRI-Defined Normal Tissue, Ischemic Penumbra and Ischemic Core. PLoS One. 2015; 10(6):e0131929. PMID: 26121129.
      Citations: 10     Fields:    Translation:AnimalsCells
    12. Shen Q, Ouyang J, Tang G, Jabbour EJ, Garcia-Manero G, Routbort M, Konoplev S, Bueso-Ramos C, Medeiros LJ, Jorgensen JL, Wang SA. Flow cytometry immunophenotypic findings in chronic myelomonocytic leukemia and its utility in monitoring treatment response. Eur J Haematol. 2015 Aug; 95(2):168-76. PMID: 25354960.
      Citations: 6     Fields:    Translation:Humans
    13. Shen Q, Sahin AA, Hess KR, Suki D, Aldape KD, Sawaya R, Ibrahim NK. Breast cancer with brain metastases: clinicopathologic features, survival, and paired biomarker analysis. Oncologist. 2015 May; 20(5):466-73. PMID: 25802405.
      Citations: 20     Fields:    Translation:Humans
    14. Li Y, Shen Q, Huang S, Li W, Muir ER, Long JA, Duong TQ. Cerebral angiography, blood flow and vascular reactivity in progressive hypertension. Neuroimage. 2015 May 01; 111:329-37. PMID: 25731987.
      Citations: 9     Fields:    Translation:Animals
    15. Talley Watts L, Long JA, Manga VH, Huang S, Shen Q, Duong TQ. Normobaric oxygen worsens outcome after a moderate traumatic brain injury. J Cereb Blood Flow Metab. 2015 Jul; 35(7):1137-44. PMID: 25690469.
      Citations: 4     Fields:    Translation:AnimalsCells
    16. Tang S, Wang X, Shen Q, Yang X, Yu C, Cai C, Cai G, Meng X, Zou F. Mitochondrial Ca²? uniporter is critical for store-operated Ca²? entry-dependent breast cancer cell migration. Biochem Biophys Res Commun. 2015 Feb 27; 458(1):186-93. PMID: 25640838.
      Citations: 30     Fields:    Translation:HumansCells
    17. Shen Q, Huang S, Duong TQ. Ultra-high spatial resolution basal and evoked cerebral blood flow MRI of the rat brain. Brain Res. 2015 Mar 02; 1599:126-36. PMID: 25557404.
      Citations: 6     Fields:    Translation:Animals
    18. Ouyang J, Zheng W, Shen Q, Goswami M, Jorgensen JL, Medeiros LJ, Wang SA. Flow cytometry immunophenotypic analysis of Philadelphia-negative myeloproliferative neoplasms: Correlation with histopathologic features. Cytometry B Clin Cytom. 2015 Jul-Aug; 88(4):236-43. PMID: 25557358.
      Citations:    Fields:    Translation:HumansCells
    19. Liu J, Cheng X, Liu D, Xu W, Wise R, Shen QH. The miR9863 family regulates distinct Mla alleles in barley to attenuate NLR receptor-triggered disease resistance and cell-death signaling. PLoS Genet. 2014 Dec; 10(12):e1004755. PMID: 25502438.
      Citations: 25     Fields:    Translation:AnimalsCells
    20. Li W, Long JA, Watts LT, Jiang Z, Shen Q, Li Y, Duong TQ. A quantitative MRI method for imaging blood-brain barrier leakage in experimental traumatic brain injury. PLoS One. 2014; 9(12):e114173. PMID: 25478693.
      Citations: 11     Fields:    Translation:HumansAnimals
    21. Ding C, Wang L, Chen H, Wild C, Ye N, Ding Y, Wang T, White MA, Shen Q, Zhou J. ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids. Org Biomol Chem. 2014 Nov 14; 12(42):8442-52. PMID: 25225052.
      Citations: 9     Fields:    Translation:Cells
    22. Li M, Ma X, Chiang YH, Yadeta KA, Ding P, Dong L, Zhao Y, Li X, Yu Y, Zhang L, Shen QH, Xia B, Coaker G, Liu D, Zhou JM. Proline isomerization of the immune receptor-interacting protein RIN4 by a cyclophilin inhibits effector-triggered immunity in Arabidopsis. . 2014 Oct 08; 16(4):473-83. PMID: 25299333.
    23. Ye N, Ding Y, Wild C, Shen Q, Zhou J. Small molecule inhibitors targeting activator protein 1 (AP-1). J Med Chem. 2014 Aug 28; 57(16):6930-48. PMID: 24831826.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    24. Chen H, Yang Z, Ding C, Xiong A, Wild C, Wang L, Ye N, Cai G, Flores RM, Ding Y, Shen Q, Zhou J. Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3). Eur J Med Chem. 2014 Jul 23; 82:195-203. PMID: 24904966.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    25. Xiong A, Yang Z, Shen Y, Zhou J, Shen Q. Transcription Factor STAT3 as a Novel Molecular Target for Cancer Prevention. Cancers (Basel). 2014 Apr 16; 6(2):926-57. PMID: 24743778.
    26. Zhou Q, Facciponte J, Jin M, Shen Q, Lin Q. Humanized NOD-SCID IL2rg–/– mice as a preclinical model for cancer research and its potential use for individualized cancer therapies. Cancer Lett. 2014 Mar 01; 344(1):13-19. PMID: 24513265.
      Citations: 29     Fields:    Translation:HumansAnimals
    27. Kong J, Kong F, Gao J, Zhang Q, Dong S, Gu F, Ke S, Pan B, Shen Q, Sun H, Zheng L, Sun W. YC-1 enhances the anti-tumor activity of sorafenib through inhibition of signal transducer and activator of transcription 3 (STAT3) in hepatocellular carcinoma. Mol Cancer. 2014 Jan 13; 13:7. PMID: 24418169.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    28. Tu H, Sun H, Lin Y, Ding J, Nan K, Li Z, Shen Q, Wei Y. Oxidative stress upregulates PDCD4 expression in patients with gastric cancer via miR-21. Curr Pharm Des. 2014; 20(11):1917-23. PMID: 23888942.
      Citations: 13     Fields:    Translation:HumansCells
    29. Shen Q, Du F, Huang S, Rodriguez P, Watts LT, Duong TQ. Neuroprotective efficacy of methylene blue in ischemic stroke: an MRI study. PLoS One. 2013; 8(11):e79833. PMID: 24278191.
      Citations: 27     Fields:    Translation:Animals
    30. Ding C, Zhang Y, Chen H, Yang Z, Wild C, Ye N, Ester CD, Xiong A, White MA, Shen Q, Zhou J. Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis. J Med Chem. 2013 Nov 14; 56(21):8814-25. PMID: 24128046.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    31. Chang C, Zhang L, Shen QH. Partitioning, repressing and derepressing: dynamic regulations in MLA immune receptor triggered defense signaling. Front Plant Sci. 2013 Oct 08; 4:396. PMID: 24115952.
    32. Shen Q, He B, Lu N, Conradt B, Grant BD, Zhou Z. Phagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans. Development. 2013 Aug; 140(15):3230-43. PMID: 23861060.
      Citations: 11     Fields:    Translation:AnimalsCells
    33. Zheng X, Li A, Zhao L, Zhou T, Shen Q, Cui Q, Qin X. Key role of microRNA-15a in the KLF4 suppressions of proliferation and angiogenesis in endothelial and vascular smooth muscle cells. Biochem Biophys Res Commun. 2013 Aug 09; 437(4):625-31. PMID: 23867820.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    34. Ding C, Zhang Y, Chen H, Wild C, Wang T, White MA, Shen Q, Zhou J. Overcoming synthetic challenges of oridonin A-ring structural diversification: regio- and stereoselective installation of azides and 1,2,3-triazoles at the C-1, C-2, or C-3 position. Org Lett. 2013 Jul 19; 15(14):3718-21. PMID: 23834026.
      Citations: 12     Fields:    Translation:Cells
    35. Ding C, Zhang Y, Chen H, Yang Z, Wild C, Chu L, Liu H, Shen Q, Zhou J. Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility. J Med Chem. 2013 Jun 27; 56(12):5048-58. PMID: 23746196.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    36. Zhou F, Shen Q, Claret FX. Novel roles of reactive oxygen species in the pathogenesis of acute myeloid leukemia. J Leukoc Biol. 2013 Sep; 94(3):423-9. PMID: 23715741.
      Citations: 22     Fields:    Translation:HumansCells
    37. Chang C, Yu D, Jiao J, Jing S, Schulze-Lefert P, Shen QH. Barley MLA immune receptors directly interfere with antagonistically acting transcription factors to initiate disease resistance signaling. Plant Cell. 2013 Mar; 25(3):1158-73. PMID: 23532068.
      Citations: 37     Fields:    Translation:AnimalsCells
    38. Chen H, Yang Z, Ding C, Chu L, Zhang Y, Terry K, Liu H, Shen Q, Zhou J. Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy. Eur J Med Chem. 2013 Apr; 62:498-507. PMID: 23416191.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    39. Meng X, Cai C, Wu J, Cai S, Ye C, Chen H, Yang Z, Zeng H, Shen Q, Zou F. TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway. Cancer Lett. 2013 Jun 01; 333(1):96-102. PMID: 23353055.
      Citations: 50     Fields:    Translation:HumansCells
    40. Bai S, Liu J, Chang C, Zhang L, Maekawa T, Wang Q, Xiao W, Liu Y, Chai J, Takken FL, Schulze-Lefert P, Shen QH. Structure-function analysis of barley NLR immune receptor MLA10 reveals its cell compartment specific activity in cell death and disease resistance. PLoS Pathog. 2012; 8(6):e1002752. PMID: 22685408.
      Citations: 66     Fields:    Translation:AnimalsCells
    41. Desai V, Shen Q, Duong TQ. Incorporating ADC temporal profiles to predict ischemic tissue fate in acute stroke. Brain Res. 2012 Jun 06; 1458:86-92. PMID: 22554478.
      Citations: 4     Fields:    Translation:AnimalsCells
    42. Lu N, Shen Q, Mahoney TR, Neukomm LJ, Wang Y, Zhou Z. Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells. PLoS Biol. 2012 Jan; 10(1):e1001245. PMID: 22272187.
      Citations: 27     Fields:    Translation:AnimalsCells
    43. Shen Q, Huang S, Du F, Duong TQ. Probing ischemic tissue fate with BOLD fMRI of brief oxygen challenge. Brain Res. 2011 Nov 24; 1425:132-41. PMID: 22032876.
      Citations: 18     Fields:    Translation:Animals
    44. Wang GF, Wei X, Fan R, Zhou H, Wang X, Yu C, Dong L, Dong Z, Wang X, Kang Z, Ling H, Shen QH, Wang D, Zhang X. Molecular analysis of common wheat genes encoding three types of cytosolic heat shock protein 90 (Hsp90): functional involvement of cytosolic Hsp90s in the control of wheat seedling growth and disease resistance. . 2011 Jul; 191(2):418-31. PMID: 21488877.
    45. Maekawa T, Cheng W, Spiridon LN, Töller A, Lukasik E, Saijo Y, Liu P, Shen QH, Micluta MA, Somssich IE, Takken FLW, Petrescu AJ, Chai J, Schulze-Lefert P. Coiled-coil domain-dependent homodimerization of intracellular barley immune receptors defines a minimal functional module for triggering cell death. . 2011 Mar 17; 9(3):187-199. PMID: 21402358.
    46. Lu N, Shen Q, Mahoney TR, Liu X, Zhou Z. Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling. Mol Biol Cell. 2011 Feb 01; 22(3):354-74. PMID: 21148288.
      Citations: 28     Fields:    Translation:AnimalsCells
    47. Li Y, Shen Q, Kim HT, Bissonnette RP, Lamph WW, Yan B, Brown PH. The rexinoid bexarotene represses cyclin D1 transcription by inducing the DEC2 transcriptional repressor. Breast Cancer Res Treat. 2011 Aug; 128(3):667-77. PMID: 20821348.
      Citations: 15     Fields:    Translation:HumansCells
    48. Shen Q, Lee ES, Pitts RL, Wu MH, Yuan SY. Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells. Mol Cancer Res. 2010 Jul; 8(7):939-51. PMID: 20571065.
      Citations: 15     Fields:    Translation:HumansCells
    49. Cai LS, Zhang JX, Shen Q, Situ HL, Song GH, Xie YC. [Features of preoperative contrast-enhanced ultrasound of breast cancer: relationship with the syndrome classification in traditional Chinese medicine]. Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jun; 30(6):1404-6. PMID: 20584690.
      Citations: 1     Fields:    Translation:Humans
    50. Shen Q, Rigor RR, Pivetti CD, Wu MH, Yuan SY. Myosin light chain kinase in microvascular endothelial barrier function. Cardiovasc Res. 2010 Jul 15; 87(2):272-80. PMID: 20479130.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    51. Chen HJ, Liu Y, Wang LN, Shen Q, Li J, Nan FJ. Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B. Bioorg Med Chem Lett. 2010 May 01; 20(9):2876-9. PMID: 20363629.
      Citations:    Fields:    Translation:Humans
    52. Xiao H, Ma X, Feng W, Fu Y, Lu Z, Xu M, Shen Q, Zhu Y, Zhang Y. Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway. Cardiovasc Res. 2010 Aug 01; 87(3):504-13. PMID: 20200042.
      Citations: 47     Fields:    Translation:AnimalsCells
    53. Strecker TE, Shen Q, Zhang Y, Hill JL, Li Y, Wang C, Kim HT, Gilmer TM, Sexton KR, Hilsenbeck SG, Osborne CK, Brown PH. Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice. J Natl Cancer Inst. 2009 Jan 21; 101(2):107-13. PMID: 19141783.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    54. Guo M, Daines D, Tang J, Shen Q, Perrin RM, Takada Y, Yuan SY, Wu MH. Fibrinogen-gamma C-terminal fragments induce endothelial barrier dysfunction and microvascular leak via integrin-mediated and RhoA-dependent mechanism. Arterioscler Thromb Vasc Biol. 2009 Mar; 29(3):394-400. PMID: 19122172.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    55. Uray IP, Shen Q, Seo HS, Kim H, Lamph WW, Bissonnette RP, Brown PH. Rexinoid-induced expression of IGFBP-6 requires RARbeta-dependent permissive cooperation of retinoid receptors and AP-1. J Biol Chem. 2009 Jan 02; 284(1):345-53. PMID: 18957410.
      Citations: 13     Fields:    Translation:HumansCells
    56. Feng X, Wang LN, Zhou YY, Yu HP, Shen Q, Zang Y, Zhou YB, Li JY, Zhang HX, Li J. Discovery and characterization of a novel inhibitor of CDC25B, LGH00045. Acta Pharmacol Sin. 2008 Oct; 29(10):1268-74. PMID: 18817634.
      Citations: 2     Fields:    Translation:HumansCells
    57. Zhang YN, Zhang W, Hong D, Shi L, Shen Q, Li JY, Li J, Hu LH. Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities. Bioorg Med Chem. 2008 Sep 15; 16(18):8697-705. PMID: 18707891.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    58. Shen Q, Rahn JJ, Zhang J, Gunasekera N, Sun X, Shaw AR, Hendzel MJ, Hoffman P, Bernier A, Hugh JC. MUC1 initiates Src-CrkL-Rac1/Cdc42-mediated actin cytoskeletal protrusive motility after ligating intercellular adhesion molecule-1. Mol Cancer Res. 2008 Apr; 6(4):555-67. PMID: 18403635.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    59. Shen Q, Uray IP, Li Y, Zhang Y, Hill J, Xu XC, Young MR, Gunther EJ, Hilsenbeck SG, Colburn NH, Chodosh LA, Brown PH. Targeting the activator protein 1 transcription factor for the prevention of estrogen receptor-negative mammary tumors. Cancer Prev Res (Phila). 2008 Jun; 1(1):45-55. PMID: 19138935.
      Citations: 11     Fields:    Translation:AnimalsCells
    60. Li Y, Zhang Y, Hill J, Kim HT, Shen Q, Bissonnette RP, Lamph WW, Brown PH. The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice. Br J Cancer. 2008 Apr 22; 98(8):1380-8. PMID: 18362934.
      Citations: 17     Fields:    Translation:AnimalsCells
    61. Shi L, Yu HP, Zhou YY, Du JQ, Shen Q, Li JY, Li J. Discovery of a novel competitive inhibitor of PTP1B by high-throughput screening. Acta Pharmacol Sin. 2008 Feb; 29(2):278-84. PMID: 18215359.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    62. Li Y, Zhang Y, Hill J, Shen Q, Kim HT, Xu X, Hilsenbeck SG, Bissonnette RP, Lamph WW, Brown PH. The Rexinoid LG100268 prevents the development of preinvasive and invasive estrogen receptor negative tumors in MMTV-erbB2 mice. Clin Cancer Res. 2007 Oct 15; 13(20):6224-31. PMID: 17947490.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    63. Shen QH, Schulze-Lefert P. Rumble in the nuclear jungle: compartmentalization, trafficking, and nuclear action of plant immune receptors. EMBO J. 2007 Oct 17; 26(20):4293-301. PMID: 17853890.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    64. Shen Q, Uray IP, Li Y, Krisko TI, Strecker TE, Kim HT, Brown PH. The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors. Oncogene. 2008 Jan 10; 27(3):366-77. PMID: 17637753.
      Citations: 51     Fields:    Translation:HumansCells
    65. Shen QH, Saijo Y, Mauch S, Biskup C, Bieri S, Keller B, Seki H, Ulker B, Somssich IE, Schulze-Lefert P. Nuclear activity of MLA immune receptors links isolate-specific and basal disease-resistance responses. Science. 2007 Feb 23; 315(5815):1098-103. PMID: 17185563.
      Citations: 233     Fields:    Translation:AnimalsCells
    66. Shen Q, Zhang Y, Uray IP, Hill JL, Kim HT, Lu C, Young MR, Gunther EJ, Hilsenbeck SG, Chodosh LA, Colburn NH, Brown PH. The AP-1 transcription factor regulates postnatal mammary gland development. Dev Biol. 2006 Jul 15; 295(2):589-603. PMID: 16678816.
      Citations: 20     Fields:    Translation:Animals
    67. Lu C, Shen Q, DuPré E, Kim H, Hilsenbeck S, Brown PH. cFos is critical for MCF-7 breast cancer cell growth. Oncogene. 2005 Sep 29; 24(43):6516-24. PMID: 16027729.
      Citations: 20     Fields:    Translation:HumansCells
    68. Shen Q, Brown PH. Transgenic mouse models for the prevention of breast cancer. Mutat Res. 2005 Aug 25; 576(1-2):93-110. PMID: 15888345.
      Citations: 9     Fields:    Translation:AnimalsCells
    69. Tang HW, Bian JC, Jiang F, Shen Q, Zhu QX, Zhang HW, Wu Y. [Single nucleotide polymorphisms and point mutations of ataxia telangiectasia mutated gene in Chinese of Han ethnicity]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004 Dec; 21(6):579-82. PMID: 15583986.
      Citations:    Fields:    Translation:Humans
    70. Bieri S, Mauch S, Shen QH, Peart J, Devoto A, Casais C, Ceron F, Schulze S, Steinbiss HH, Shirasu K, Schulze-Lefert P. RAR1 positively controls steady state levels of barley MLA resistance proteins and enables sufficient MLA6 accumulation for effective resistance. Plant Cell. 2004 Dec; 16(12):3480-95. PMID: 15548741.
      Citations: 84     Fields:    Translation:AnimalsCells
    71. Liu Y, Lu C, Shen Q, Munoz-Medellin D, Kim H, Brown PH. AP-1 blockade in breast cancer cells causes cell cycle arrest by suppressing G1 cyclin expression and reducing cyclin-dependent kinase activity. Oncogene. 2004 Oct 28; 23(50):8238-46. PMID: 15378019.
      Citations: 26     Fields:    Translation:HumansCells
    72. Shen Q, Singh P. Identification of a novel SP3 binding site in the promoter of human IGFBP4 gene: role of SP3 and AP-1 in regulating promoter activity in CaCo2 cells. Oncogene. 2004 Apr 01; 23(14):2454-64. PMID: 14767471.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    73. Lu C, Speers C, Zhang Y, Xu X, Hill J, Steinbis E, Celestino J, Shen Q, Kim H, Hilsenbeck S, Mohsin SK, Wakeling A, Osborne CK, Brown PH. Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors. J Natl Cancer Inst. 2003 Dec 17; 95(24):1825-33. PMID: 14679152.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    74. Luo QL, Li JY, Liu ZY, Chen LL, Li J, Qian Z, Shen Q, Li Y, Lushington GH, Ye QZ, Nan FJ. Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae. J Med Chem. 2003 Jun 19; 46(13):2631-40. PMID: 12801227.
      Citations: 22     Fields:    Translation:AnimalsCells
    75. Shen QH, Zhou F, Bieri S, Haizel T, Shirasu K, Schulze-Lefert P. Recognition specificity and RAR1/SGT1 dependence in barley Mla disease resistance genes to the powdery mildew fungus. Plant Cell. 2003 Mar; 15(3):732-44. PMID: 12615945.
      Citations: 64     Fields:    Translation:AnimalsCells
    76. Shen Q, Brown PH. Novel agents for the prevention of breast cancer: targeting transcription factors and signal transduction pathways. J Mammary Gland Biol Neoplasia. 2003 Jan; 8(1):45-73. PMID: 14587863.
      Citations: 16     Fields:    Translation:HumansCells
    77. Fan X, Croll RP, Wu B, Fang L, Shen Q, Painter SD, Nagle GT. Molecular cloning of a cDNA encoding the neuropeptides APGWamide and cerebral peptide 1: localization of APGWamide-like immunoreactivity in the central nervous system and male reproductive organs of Aplysia. J Comp Neurol. 1997 Oct 13; 387(1):53-62. PMID: 9331171.
      Citations: 10     Fields:    Translation:AnimalsCells
    78. Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine. Oncotarget. 7:37192-37204.
    79. Gemcitabine treatment promotes pancreatic cancer stemness through the Nox/ROS/NF-κB/STAT3 signaling cascade. Cancer Letters. 382:53-63.
    80. Downregulation of ACE2/Ang-(1-7)/Mas axis promotes breast cancer metastasis by enhancing store-operated calcium entry. Cancer Letters. 376:268-277.
    81. Traditional Chinese medicine targeting apoptotic mechanisms for esophageal cancer therapy. Acta Pharmacologica Sinica. 37:295-302.
    82. Targeting STAT3/miR-21 axis inhibits epithelial-mesenchymal transition via regulating CDK5 in head and neck squamous cell carcinoma. Molecular Cancer. 14.
    83. Small molecule inhibitors targeting activator protein 1 (AP-1). Journal of Medicinal Chemistry. 57:6930-6948.
    84. Discovery and development of natural product oridonin-inspired anticancer agents. European Journal of Medicinal Chemistry. 122:102-117.
    85. Qigesan inhibits migration and invasion of esophageal cancer cells via inducing connexin expression and enhancing gap junction function. Cancer Letters. 380:184-190.
    86. AP-1 blockade in vivo suppresses development of mammary tumor im MMTV- erbB2 mice. Cancer Epidemiology, Biomarkers and Prevention. 14.
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