Header Logo

ABHINAV JAIN

TitleInstructor
InstitutionMD Anderson
DepartmentEpigenetics & Molecular Carcinogenesis
Address6767 Bertner St
Houston TX 77030-2603
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhou J, Chen Q, Ren R, Yang J, Liu B, Horton JR, Chang C, Li C, Maksoud L, Yang Y, Rotili D, Jain AK, Zhang X, Blumenthal RM, Chen T, Gao Y, Valente S, Mai A, Cheng X. Quinoline-based compounds can inhibit diverse enzymes that act on DNA. Cell Chem Biol. 2024 Oct 14. PMID: 39437789.
      Citations:    Fields:    
    2. Asemota S, Effah W, Holt J, Johnson D, Cripe L, Ponnusamy S, Thiyagarajan T, Khosrosereshki Y, Hwang DJ, He Y, Grimes B, Fleming MD, Pritchard FE, Hendrix A, Fan M, Jain A, Choi HY, Makowski L, Hayes DN, Miller DD, Pfeffer LM, Santhanam B, Narayanan R. A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity. Proc Natl Acad Sci U S A. 2024 Oct; 121(40):e2406837121. PMID: 39312663; PMCID: PMC11459127.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Lee HM, Saw AK, Morris VK, Napolitano S, Bristow C, Srinivasan S, Peoples M, Sorokin A, Kanikarla Marie P, Schulz J, Singh AK, Terranova C, Coker O, Jain A, Kopetz S, Rai K. Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer. Clin Cancer Res. 2024 Sep 13. PMID: 39269307.
      Citations:    Fields:    
    4. Kumar B, Singh A, Basar R, Uprety N, Li Y, Fan H, Cortes AKN, Kaplan M, Acharya S, Shaim H, Xu AC, Wu M, Ensley E, Fang D, Banerjee PP, Garcia LM, Tiberti S, Lin P, Rafei H, Munir MN, Moore M, Shanley M, Mendt M, Kerbauy LN, Liu B, Biederst?dt A, Gokdemir E, Ghosh S, Kundu K, Reyes-Silva F, Jiang XR, Wan X, Gilbert AL, Dede M, Mohanty V, Dou J, Zhang P, Liu E, Muniz-Feliciano L, Deyter GM, Jain AK, Rodriguez-Sevilla JJ, Colla S, Garcia-Manero G, Shpall EJ, Chen K, Abbas HA, Rai K, Rezvani K, Daher M. BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. Sci Transl Med. 2024 Sep 11; 16(764):eadp0004. PMID: 39259809.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Shanley M, Daher M, Dou J, Li S, Basar R, Rafei H, Dede M, Gumin J, Pantale?n Garc?a J, Nunez Cortes AK, He S, Jones CM, Acharya S, Fowlkes NW, Xiong D, Singh S, Shaim H, Hicks SC, Liu B, Jain A, Zaman MF, Miao Q, Li Y, Uprety N, Liu E, Muniz-Feliciano L, Deyter GM, Mohanty V, Zhang P, Evans SE, Shpall EJ, Lang FF, Chen K, Rezvani K. Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD. Cancer Cell. 2024 Aug 12; 42(8):1450-1466.e11. PMID: 39137729; PMCID: PMC11370652.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Sturmlechner I, Jain A, Hu B, Jadhav RR, Cao W, Okuyama H, Tian L, Weyand CM, Goronzy JJ. Aging trajectories of memory CD8 + T cells differ by their antigen specificity. bioRxiv. 2024 Jul 29. PMID: 39211225; PMCID: PMC11360919.
      Citations:    
    7. Deogharia M, Venegas-Zamora L, Agrawal A, Shi M, Jain AK, McHugh KJ, Altamirano F, Marian AJ, Gurha P, Deogharia M, Venegas-Zamora L, Agrawal A, Shi M, Jain AK, McHugh KJ, Altamirano F, Marian AJ, Gurha P. Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization. Cardiovasc Res. 2024 May 07; 120(6):630-643. PMID: 38230606; PMCID: PMC11074792.
      Citations: 5     Fields:    Translation:HumansCells
    8. Kumar Manokaran R, Mishra A, Rawat S, Mohanty S, Gulati S, Gupta N, Kabra M, Sabharwal A, Gupta V, Kv S, Verma A, Bhoyar RC, Jain A, Sivadas A, Jolly B, Scaria V, Sivasubbu S. Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics leading to infant mortality. Mitochondrion. 2024 Mar; 75:101844. PMID: 38237647.
      Citations:    Fields:    Translation:HumansCells
    9. Sato Y, Jain A, Ohtsuki S, Okuyama H, Sturmlechner I, Takashima Y, Le KC, Bois MC, Berry GJ, Warrington KJ, Goronzy JJ, Weyand CM. Stem-like CD4+ T cells in perivascular tertiary lymphoid structures sustain autoimmune vasculitis. Sci Transl Med. 2023 09 06; 15(712):eadh0380. PMID: 37672564; PMCID: PMC11131576.
      Citations:    
    10. Mahadevan KK, LeBleu VS, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M, Ying H, Jain AK, DePinho RA, Maitra A, McAndrews KM, Kalluri R. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T?cells. Dev Cell. 2023 09 11; 58(17):1562-1577.e8. PMID: 37625403; PMCID: PMC10810082.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    11. Saha D, Hailu S, Hada A, Lee J, Luo J, Ranish JA, Lin YC, Feola K, Persinger J, Jain A, Liu B, Lu Y, Sen P, Bartholomew B. The AT-hook is an evolutionarily conserved auto-regulatory domain of SWI/SNF required for cell lineage priming. Nat Commun. 2023 08 04; 14(1):4682. PMID: 37542049; PMCID: PMC10403523.
      Citations:    Fields:    Translation:AnimalsCells
    12. Fan H, Wang F, Zeng A, Murison A, Tomczak K, Hao D, Jelloul FZ, Wang B, Barrodia P, Liang S, Chen K, Wang L, Zhao Z, Rai K, Jain AK, Dick J, Daver N, Futreal A, Abbas HA. Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance. Commun Biol. 2023 07 21; 6(1):765. PMID: 37479893; PMCID: PMC10362028.
      Citations: 1     Translation:HumansCells
    13. Gencel-Augusto J, Su X, Qi Y, Whitley EM, Pant V, Xiong S, Shah V, Lin J, Perez E, Fiorotto ML, Mahmud I, Jain AK, Lorenzi PL, Navin NE, Richie ER, Lozano G. Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. Cancer Discov. 2023 05 04; 13(5):1230-1249. PMID: 37067911; PMCID: PMC10164062.
      Citations: 3     Fields:    Translation:Animals
    14. Pathak AK, Mishra GP, Uppili B, Walia S, Fatihi S, Abbas T, Banu S, Ghosh A, Kanampalliwar A, Jha A, Fatma S, Aggarwal S, Dhar MS, Marwal R, Radhakrishnan VS, Ponnusamy K, Kabra S, Rakshit P, Bhoyar RC, Jain A, Divakar MK, Imran M, Faruq M, Sowpati DT, Thukral L, Raghav SK, Mukerji M. Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes. Nucleic Acids Res. 2022 02 22; 50(3):1551-1561. PMID: 35048970; PMCID: PMC8860616.
      Citations: 2     Fields:    Translation:AnimalsCells
    15. Piya S, Yang Y, Bhattacharya S, Sharma P, Ma H, Mu H, He H, Ruvolo V, Baran N, Davis RE, Jain AK, Konopleava M, Kantarjian H, Andreeff M, You MJ, Borthakur G. Targeting the NOTCH1-MYC-CD44 axis in leukemia-initiating cells in T-ALL. Leukemia. 2022 05; 36(5):1261-1273. PMID: 35173274; PMCID: PMC9061299.
      Citations:    Fields:    Translation:HumansAnimalsCells
    16. Van HT, Harkins PR, Patel A, Jain AK, Lu Y, Bedford MT, Santos MA. Methyl-lysine readers PHF20 and PHF20L1 define two distinct?gene expression-regulating NSL complexes. J Biol Chem. 2022 03; 298(3):101588. PMID: 35033534; PMCID: PMC8867114.
      Citations:    Fields:    Translation:Cells
    17. Shah VV, Duncan AD, Jiang S, Stratton SA, Allton KL, Yam C, Jain A, Krause PM, Lu Y, Cai S, Tu Y, Zhou X, Zhang X, Jiang Y, Carroll CL, Kang Z, Liu B, Shen J, Gagea M, Manu SM, Huo L, Gilcrease M, Powell RT, Guo L, Stephan C, Davies PJ, Parker-Thornburg J, Lozano G, Behringer RR, Piwnica-Worms H, Chang JT, Moulder SL, Barton MC. Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. Nat Commun. 2021 09 10; 12(1):5389. PMID: 34508101; PMCID: PMC8433435.
      Citations: 1     Fields:    Translation:HumansAnimals
    18. Zhu M, Peng R, Liang X, Lan Z, Tang M, Hou P, Song JH, Mak CSL, Park J, Zheng SE, Huang A, Ma X, Chen R, Chang Q, Logothetis CJ, Jain AK, Lin SH, Katayama H, Hanash S, Wang G. P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis. Oncogene. 2021 10; 40(41):6049-6056. PMID: 34471235; PMCID: PMC8526415.
      Citations: 3     Fields:    Translation:HumansAnimals
    19. Jain A, Bhoyar RC, Pandhare K, Mishra A, Sharma D, Imran M, Senthivel V, Divakar MK, Rophina M, Jolly B, Batra A, Sharma S, Siwach S, Jadhao AG, Palande NV, Jha GN, Ashrafi N, Mishra PK, A K V, Jain S, Dash D, Kumar NS, Vanlallawma A, Sarma RJ, Chhakchhuak L, Kalyanaraman S, Mahadevan R, Kandasamy S, B M P, Rajagopal RE, J ER, P ND, Bajaj A, Gupta V, Mathew S, Goswami S, Mangla M, Prakash S, Joshi K, S S, Gajjar D, Soraisham R, Yadav R, Devi YS, Gupta A, Mukerji M, Ramalingam S, B K B, Scaria V, Sivasubbu S. IndiGenomes: a comprehensive resource of genetic variants from over 1000 Indian genomes. Nucleic Acids Res. 2021 01 08; 49(D1):D1225-D1232. PMID: 33095885; PMCID: PMC7778947.
      Citations: 10     Fields:    Translation:Humans
    20. Kumar A, Raman A, Yadav S, Verulkar SB, Mandal NP, Singh ON, Swain P, Ram T, Badri J, Dwivedi JL, Das SP, Singh SK, Singh SP, Kumar S, Jain A, Chandrababu R, Robin S, Shashidhar HE, Hittalmani S, Satyanarayana P, Venkateshwarlu C, Ramayya J, Naik S, Nayak S, Dar MH, Hossain SM, Henry A, Piepho HP. Genetic gain for rice yield in rainfed environments in India. Field Crops Res. 2021 Jan 01; 260:107977. PMID: 33390645; PMCID: PMC7722510.
      Citations:    
    21. Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N. Correction: Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene. 2020 Oct; 39(40):6387-6392. PMID: 32820250.
      Citations: 2     Fields:    
    22. Jain AK. Emerging roles of long non-coding RNAs in the p53 network. RNA Biol. 2020 11; 17(11):1648-1656. PMID: 32432959; PMCID: PMC7567491.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    23. Liang J, Wang L, Wang C, Shen J, Su B, Marisetty AL, Fang D, Kassab C, Jeong KJ, Zhao W, Lu Y, Jain AK, Zhou Z, Liang H, Sun SC, Lu C, Xu ZX, Yu Q, Shao S, Chen X, Gao M, Claret FX, Ding Z, Chen J, Chen P, Barton MC, Peng G, Mills GB, Heimberger AB. Verteporfin Inhibits PD-L1 through Autophagy and the STAT1-IRF1-TRIM28 Signaling Axis, Exerting Antitumor Efficacy. Cancer Immunol Res. 2020 07; 8(7):952-965. PMID: 32265228; PMCID: PMC8204534.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    24. Tandon N, Goller K, Wang F, Soibam B, Gagea M, Jain AK, Schwartz RJ, Liu Y. Aberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesis. EBioMedicine. 2019 Dec; 50:55-66. PMID: 31761621; PMCID: PMC6921370.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    25. Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N. Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene. 2020 10; 39(40):6265-6285. PMID: 31383940; PMCID: PMC8058741.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    26. Jain AK, Barton MC. p53: emerging roles in stem cells, development and beyond. Development. 2018 04 13; 145(8). PMID: 29654218.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    27. Bosnakovski D, Gearhart MD, Toso EA, Recht OO, Cucak A, Jain AK, Barton MC, Kyba M. p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy. Dis Model Mech. 2017 10 01; 10(10):1211-1216. PMID: 28754837; PMCID: PMC5665455.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    28. Niture SK, Jain AK, Jaiswal AK. Retraction: Antioxidant-induced modification of INrf2 cysteine 151 and PKC-d-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance. J Cell Sci. 2017 02 15; 130(4):816. PMID: 28202606; PMCID: PMC6371686.
      Citations:    Fields:    
    29. Niture SK, Jain AK, Shelton PM, Jaiswal AK. Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression. J Biol Chem. 2017 02 03; 292(5):2048. PMID: 28159761; PMCID: PMC5290975.
      Citations: 3     Fields:    
    30. Jain AK, Mahajan S, Jaiswal AK. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2. A NOVEL MECHANISM IN NRF2 ACTIVATION. J Biol Chem. 2017 02 03; 292(5):2050. PMID: 28159763; PMCID: PMC5290977.
      Citations:    Fields:    
    31. Jain AK, Jaiswal AK. Phosphorylation of tyrosine 568 controls nuclear export of Nrf2. J Biol Chem. 2017 02 03; 292(5):2051. PMID: 28159764; PMCID: PMC5290978.
      Citations: 3     Fields:    
    32. Jain AK, Bloom DA, Jaiswal AK. Nuclear import and export signals in control of Nrf2. J Biol Chem. 2017 02 03; 292(5):2052. PMID: 28159765; PMCID: PMC5290979.
      Citations: 2     Fields:    
    33. Jain AK, Xi Y, McCarthy R, Allton K, Akdemir KC, Patel LR, Aronow B, Lin C, Li W, Yang L, Barton MC. LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56. Mol Cell. 2016 12 01; 64(5):967-981. PMID: 27912097; PMCID: PMC5137794.
      Citations: 78     Fields:    Translation:HumansCells
    34. Jain AK, Barton MC. Bromodomain Histone Readers and Cancer. J Mol Biol. 2017 06 30; 429(13):2003-2010. PMID: 27890782.
      Citations: 33     Fields:    Translation:Cells
    35. Jain AK, Barton MC. Outside the p53 RING: Transcription Regulation by Chromatin-Bound MDM2. Mol Cell. 2016 06 16; 62(6):805-807. PMID: 27315554.
      Citations: 3     Fields:    Translation:HumansCells
    36. Niture SK, Jain AK, Shelton PM, Jaiswal AK. Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to swtich off Nrf2-mediated antioxidant activation of cytoprotective gene expression. J Biol Chem. 2016 01 15; 291(3):1199. PMID: 26773125; PMCID: PMC4714203.
      Citations:    Fields:    Translation:HumansAnimalsCells
    37. Jain AK, Mahajan S, Jaiswal AK. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2. A novel mechanism in Nrf2 activation. J Biol Chem. 2016 01 15; 291(3):1199. PMID: 26773127; PMCID: PMC4714205.
      Citations:    Fields:    Translation:Humans
    38. Jain AK, Allton K, Duncan AD, Barton MC. TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage. Mol Cell Biol. 2014 Jul; 34(14):2695-709. PMID: 24820418; PMCID: PMC4097665.
      Citations: 38     Fields:    Translation:HumansCells
    39. Akdemir KC, Jain AK, Allton K, Aronow B, Xu X, Cooney AJ, Li W, Barton MC. Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells. Nucleic Acids Res. 2014 Jan; 42(1):205-23. PMID: 24078252; PMCID: PMC3874181.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    40. Jain AK, Barton MC. Unmet expectations: miR-34 plays no role in p53-mediated tumor suppression in vivo. PLoS Genet. 2012; 8(7):e1002859. PMID: 22870065; PMCID: PMC3411369.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    41. Jain AK, Allton K, Iacovino M, Mahen E, Milczarek RJ, Zwaka TP, Kyba M, Barton MC. p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol. 2012; 10(2):e1001268. PMID: 22389628; PMCID: PMC3289600.
      Citations: 117     Fields:    Translation:HumansCells
    42. Niture SK, Jain AK, Shelton PM, Jaiswal AK. Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression. J Biol Chem. 2011 Aug 19; 286(33):28821-28834. PMID: 21690096; PMCID: PMC3190690.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    43. Jain AK, Barton MC. Making sense of ubiquitin ligases that regulate p53. Cancer Biol Ther. 2010 Oct 01; 10(7):665-72. PMID: 20930521; PMCID: PMC3023569.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    44. Niture SK, Jain AK, Jaiswal AK. Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance. J Cell Sci. 2009 Dec 15; 122(Pt 24):4452-64. PMID: 19920073; PMCID: PMC2787459.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    45. Jain AK, Barton MC. Regulation of p53: TRIM24 enters the RING. Cell Cycle. 2009 Nov 15; 8(22):3668-74. PMID: 19844164.
      Citations: 36     Fields:    Translation:AnimalsCells
    46. Minard ME, Jain AK, Barton MC. Analysis of epigenetic alterations to chromatin during development. Genesis. 2009 Aug; 47(8):559-72. PMID: 19603511; PMCID: PMC2751662.
      Citations: 16     Fields:    Translation:Cells
    47. Allton K, Jain AK, Herz HM, Tsai WW, Jung SY, Qin J, Bergmann A, Johnson RL, Barton MC. Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci U S A. 2009 Jul 14; 106(28):11612-6. PMID: 19556538; PMCID: PMC2710642.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
    48. Jain AK, Mahajan S, Jaiswal AK. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2: a novel mechanism in Nrf2 activation. J Biol Chem. 2008 Jun 20; 283(25):17712-20. PMID: 18434303; PMCID: PMC2427343.
      Citations: 17     Fields:    Translation:HumansCells
    49. Lee OH, Jain AK, Papusha V, Jaiswal AK. An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance. J Biol Chem. 2007 Dec 14; 282(50):36412-20. PMID: 17925401.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    50. Jain AK, Jaiswal AK. GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2. J Biol Chem. 2007 Jun 01; 282(22):16502-10. PMID: 17403689.
      Citations: 185     Fields:    Translation:HumansAnimalsCells
    51. Ahn KS, Sethi G, Jain AK, Jaiswal AK, Aggarwal BB. Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis. J Biol Chem. 2006 Jul 21; 281(29):19798-808. PMID: 16682409.
      Citations: 51     Fields:    Translation:AnimalsCells
    52. Jain AK, Jaiswal AK. Phosphorylation of tyrosine 568 controls nuclear export of Nrf2. J Biol Chem. 2006 Apr 28; 281(17):12132-42. PMID: 16513647.
      Citations: 78     Fields:    Translation:HumansCells
    53. Jain AK, Bloom DA, Jaiswal AK. Nuclear import and export signals in control of Nrf2. J Biol Chem. 2005 Aug 12; 280(32):29158-68. PMID: 15901726.
      Citations: 86     Fields:    Translation:HumansCells
    54. Dhakshinamoorthy S, Jain AK, Bloom DA, Jaiswal AK. Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants. J Biol Chem. 2005 Apr 29; 280(17):16891-900. PMID: 15734732.
      Citations: 162     Fields:    Translation:HumansCells
    55. Outside the p53 RING. Molecular Cell. 62:805-807.
    56. Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance (Journal of Cell Science (2010) 123, 11, (1969)). Journal of Cell Science. 123:1969.
    57. Bromodomain Histone Readers and Cancer. Journal of Molecular Biology.
    58. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2. A novel mechanism in Nrf2 activation (Journal of Biological Chemistry (2008) 283 (17712-17720)). Journal of Biological Chemistry. 291:1199.
    59. TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation. Oncogene.
    60. Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells. Nucleic Acids Research. 42:205-223.
    61. LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56. Molecular Cell. 64:967-981.
    62. Erratum. Journal of Biological Chemistry. 291:1199.
    JAIN's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (288)
    Explore
    _
    Co-Authors (53)
    Explore
    _
    Similar People (59)
    Explore
    _
    Same Department Expand Description
    Explore
    _