TitleAssociate Professor
InstitutionMD Anderson
DepartmentEpigenetics & Molecular Carcinogenesis
AddressPO Box 389
Smithville TX 78957-0389
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wang L, Yang L, Wang C, Zhao W, Ju Z, Zhang W, Shen J, Peng Y, An C, Luu YT, Song S, Yap TA, Ajani JA, Mills GB, Shen X, Peng G. Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumors. J Clin Invest. 2020 11 02; 130(11):5951-5966. PMID: 33016929; PMCID: PMC7598069.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    2. Klages-Mundt NL, Kumar A, Zhang Y, Kapoor P, Shen X. The Nature of Actin-Family Proteins in Chromatin-Modifying Complexes. Front Genet. 2018; 9:398. PMID: 30319687; PMCID: PMC6167448.
      Citations: 14     
    3. Shen J, Ju Z, Zhao W, Wang L, Peng Y, Ge Z, Nagel ZD, Zou J, Wang C, Kapoor P, Ma X, Ma D, Liang J, Song S, Liu J, Samson LD, Ajani JA, Li GM, Liang H, Shen X, Mills GB, Peng G. ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade. Nat Med. 2018 05; 24(5):556-562. PMID: 29736026; PMCID: PMC6076433.
      Citations: 154     Fields:    Translation:HumansAnimalsCells
    4. Kapoor P, Shen X. SWI/SNF chromatin remodeling complex regulates a non-chromatin substrate. Cell Cycle. 2015 Aug 03; 14(15):2379-80. PMID: 26217881; PMCID: PMC4613546.
      Citations:    Fields:    Translation:AnimalsCells
    5. Shen J, Peng Y, Wei L, Zhang W, Yang L, Lan L, Kapoor P, Ju Z, Mo Q, Shih IeM, Uray IP, Wu X, Brown PH, Shen X, Mills GB, Peng G. ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors. Cancer Discov. 2015 Jul; 5(7):752-67. PMID: 26069190; PMCID: PMC4497871.
      Citations: 165     Fields:    Translation:HumansAnimalsCells
    6. Kapoor P, Bao Y, Xiao J, Espejo A, Yang L, Bedford MT, Peng G, Shen X. Phosphorylation-Dependent Enhancement of Rad53 Kinase Activity through the INO80 Chromatin Remodeling Complex. Mol Cell. 2015 Jun 04; 58(5):863-9. PMID: 25959398; PMCID: PMC4485934.
      Citations: 5     Fields:    Translation:AnimalsCells
    7. Kapoor P, Shen X. Mechanisms of nuclear actin in chromatin-remodeling complexes. Trends Cell Biol. 2014 Apr; 24(4):238-46. PMID: 24246764; PMCID: PMC3995414.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    8. Kapoor P, Chen M, Winkler DD, Luger K, Shen X. Evidence for monomeric actin function in INO80 chromatin remodeling. Nat Struct Mol Biol. 2013 Apr; 20(4):426-32. PMID: 23524535; PMCID: PMC3618487.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    9. Falbo KB, Shen X. Function of the INO80 chromatin remodeling complex in DNA replication. Front Biosci (Landmark Ed). 2012 01 01; 17(3):970-5. PMID: 22201784; PMCID: PMC3995410.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    10. Bao Y, Shen X. SnapShot: Chromatin remodeling: INO80 and SWR1. Cell. 2011 Jan 07; 144(1):158-158.e2. PMID: 21215376; PMCID: PMC3995411.
      Citations: 23     Fields:    Translation:AnimalsCells
    11. Jiang Y, Wang X, Bao S, Guo R, Johnson DG, Shen X, Li L. INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway. Proc Natl Acad Sci U S A. 2010 Oct 05; 107(40):17274-9. PMID: 20855601; PMCID: PMC2951448.
      Citations: 57     Fields:    Translation:AnimalsCells
    12. Falbo KB, Shen X. The tango of histone marks and chaperones at replication fork. Mol Cell. 2010 Mar 12; 37(5):595-6. PMID: 20227364.
      Citations:    Fields:    Translation:HumansAnimalsCells
    13. Falbo KB, Alabert C, Katou Y, Wu S, Han J, Wehr T, Xiao J, He X, Zhang Z, Shi Y, Shirahige K, Pasero P, Shen X. Involvement of a chromatin remodeling complex in damage tolerance during DNA replication. Nat Struct Mol Biol. 2009 Nov; 16(11):1167-72. PMID: 19855395; PMCID: PMC2974178.
      Citations: 54     Fields:    Translation:AnimalsCells
    14. Falbo KB, Shen X. Histone modifications during DNA replication. Mol Cells. 2009 Sep; 28(3):149-54. PMID: 19779690.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    15. Morrison AJ, Shen X. Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes. Nat Rev Mol Cell Biol. 2009 Jun; 10(6):373-84. PMID: 19424290; PMCID: PMC6103619.
      Citations: 152     Fields:    Translation:HumansAnimalsCells
    16. Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell. 2007 Aug 10; 130(3):499-511. PMID: 17693258.
      Citations: 62     Fields:    Translation:AnimalsCells
    17. Yu EY, Steinberg-Neifach O, Dandjinou AT, Kang F, Morrison AJ, Shen X, Lue NF. Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex. Mol Cell Biol. 2007 Aug; 27(16):5639-49. PMID: 17562861; PMCID: PMC1952117.
      Citations: 27     Fields:    Translation:Cells
    18. Bao Y, Shen X. SnapShot: chromatin remodeling complexes. Cell. 2007 May 04; 129(3):632. PMID: 17482554.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    19. Chen M, Shen X. Nuclear actin and actin-related proteins in chromatin dynamics. Curr Opin Cell Biol. 2007 Jun; 19(3):326-30. PMID: 17467255.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    20. Bao Y, Shen X. Chromatin remodeling in DNA double-strand break repair. Curr Opin Genet Dev. 2007 Apr; 17(2):126-31. PMID: 17320375.
      Citations: 59     Fields:    Translation:Cells
    21. Bao Y, Shen X. INO80 subfamily of chromatin remodeling complexes. Mutat Res. 2007 May 01; 618(1-2):18-29. PMID: 17316710; PMCID: PMC2699258.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    22. Bao Y, Shen X. Asf1, a loveseat for a histone couple. Cell. 2006 Nov 03; 127(3):458-60. PMID: 17081967.
      Citations: 3     Fields:    Translation:AnimalsCells
    23. Osley MA, Shen X. Altering nucleosomes during DNA double-strand break repair in yeast. Trends Genet. 2006 Dec; 22(12):671-7. PMID: 16997415.
      Citations: 21     Fields:    Translation:AnimalsCells
    24. Falbo KB, Shen X. Chromatin remodeling in DNA replication. J Cell Biochem. 2006 Mar 01; 97(4):684-9. PMID: 16365876.
      Citations: 18     Fields:    Translation:AnimalsCells
    25. Morrison AJ, Shen X. Chromatin modifications in DNA repair. Results Probl Cell Differ. 2006; 41:109-25. PMID: 16909893.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    26. Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, Onishi M, Datta N, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE, Durocher D, Greenblatt JF, Krogan NJ. A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature. 2006 Jan 26; 439(7075):497-501. PMID: 16299494.
      Citations: 225     Fields:    Translation:AnimalsCells
    27. Morrison AJ, Shen X. DNA repair in the context of chromatin. Cell Cycle. 2005 Apr; 4(4):568-71. PMID: 15753656.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    28. Morrison AJ, Highland J, Krogan NJ, Arbel-Eden A, Greenblatt JF, Haber JE, Shen X. INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell. 2004 Dec 17; 119(6):767-75. PMID: 15607974.
      Citations: 253     Fields:    Translation:AnimalsCells
    29. Shen X. Preparation and analysis of the INO80 complex. Methods Enzymol. 2004; 377:401-12. PMID: 14979041.
      Citations: 29     Fields:    Translation:AnimalsCells
    30. Mizuguchi G, Shen X, Landry J, Wu WH, Sen S, Wu C. ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science. 2004 Jan 16; 303(5656):343-8. PMID: 14645854.
      Citations: 615     Fields:    Translation:AnimalsCells
    31. Shen X, Ranallo R, Choi E, Wu C. Involvement of actin-related proteins in ATP-dependent chromatin remodeling. Mol Cell. 2003 Jul; 12(1):147-55. PMID: 12887900.
      Citations: 168     Fields:    Translation:AnimalsCells
    32. Rottbauer W, Saurin AJ, Lickert H, Shen X, Burns CG, Wo ZG, Kemler R, Kingston R, Wu C, Fishman M. Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. Cell. 2002 Nov 27; 111(5):661-72. PMID: 12464178.
      Citations: 80     Fields:    Translation:AnimalsCells
    33. Shen X, Xiao H, Ranallo R, Wu WH, Wu C. Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates. Science. 2003 Jan 03; 299(5603):112-4. PMID: 12434013.
      Citations: 143     Fields:    Translation:AnimalsCells
    34. Shen X, Mizuguchi G, Hamiche A, Wu C. A chromatin remodelling complex involved in transcription and DNA processing. Nature. 2000 Aug 03; 406(6795):541-4. PMID: 10952318.
      Citations: 320     Fields:    Translation:AnimalsCells
    35. Shen X, Gorovsky MA. Linker histone H1 regulates specific gene expression but not global transcription in vivo. Cell. 1996 Aug 09; 86(3):475-83. PMID: 8756729.
      Citations: 120     Fields:    Translation:AnimalsCells
    36. Shen X, Yu L, Weir JW, Gorovsky MA. Linker histones are not essential and affect chromatin condensation in vivo. Cell. 1995 Jul 14; 82(1):47-56. PMID: 7606784.
      Citations: 93     Fields:    Translation:AnimalsCells
    37. Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease. American Journal of Human Genetics. 100:21-30.
    38. Chromatin remodeling in DNA repair and replication. 491-527.
    39. Erratum. Nature. 441:120.
    40. Chromatin responses to DNA damage. 79-100.
    41. The INO80 chromatin remodeling complex. 2363-2368.
    42. Editorial. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 618:1-2.
    43. Stringing Nucleosome Necklaces in the Yeast Genome. Cell. 167:600-601.
    44. Structure of the intact ATM/Tel1 kinase. Nature Communications. 7.
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