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LAURA BOVER

TitleAssociate Professor
InstitutionMD Anderson
DepartmentGenomic Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bi E, Li R, Bover LC, Li H, Su P, Ma X, Huang C, Wang Q, Liu L, Yang M, Lin Z, Qian J, Fu W, Liu YJ, Yi Q. E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs. J Clin Invest. 2018 Nov 01; 128(11):4821-4831. PMID: 30277474.
      View in: PubMed
    2. Qin H, Wei G, Sakamaki I, Dong Z, Cheng WA, Smith DL, Wen F, Sun H, Kim K, Cha S, Bover L, Neelapu SS, Kwak LW. Novel BAFF-Receptor Antibody to Natively Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies In Vivo. Clin Cancer Res. 2018 03 01; 24(5):1114-1123. PMID: 29180606.
      View in: PubMed
    3. Jiang H, Rivera-Molina Y, Gomez-Manzano C, Clise-Dwyer K, Bover L, Vence LM, Yuan Y, Lang FF, Toniatti C, Hossain MB, Fueyo J. Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination. Cancer Res. 2017 07 15; 77(14):3894-3907. PMID: 28566332.
      View in: PubMed
    4. Puebla-Osorio N, Damiani E, Bover L, Ullrich SE. Platelet-activating factor induces cell cycle arrest and disrupts the DNA damage response in mast cells. Cell Death Dis. 2015 May 07; 6:e1745. PMID: 25950475.
      View in: PubMed
    5. Karjalainen K, Jaalouk DE, Bueso-Ramos C, Bover L, Sun Y, Kuniyasu A, Driessen WH, Cardó-Vila M, Rietz C, Zurita AJ, O'Brien S, Kantarjian HM, Cortes JE, Calin GA, Koivunen E, Arap W, Pasqualini R. Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens. Clin Cancer Res. 2015 Jul 01; 21(13):3041-51. PMID: 25779950.
      View in: PubMed
    6. Arumugam T, Deng D, Bover L, Wang H, Logsdon CD, Ramachandran V. New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice. Mol Cancer Ther. 2015 Apr; 14(4):941-51. PMID: 25646014.
      View in: PubMed
    7. Voo KS, Bover L, Harline ML, Weng J, Sugimoto N, Liu YJ. Targeting of TLRs inhibits CD4+ regulatory T cell function and activates lymphocytes in human peripheral blood mononuclear cells. J Immunol. 2014 Jul 15; 193(2):627-34. PMID: 24928999.
      View in: PubMed
    8. Voo KS, Foglietta M, Percivalle E, Chu F, Nattamai D, Harline M, Lee ST, Bover L, Lin HY, Baladandayuthapani V, Delgado D, Luong A, Davis RE, Kwak LW, Liu YJ, Neelapu SS. Selective targeting of Toll-like receptors and OX40 inhibit regulatory T-cell function in follicular lymphoma. Int J Cancer. 2014 Dec 15; 135(12):2834-46. PMID: 24771328.
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    9. Hu J, Vien LT, Xia X, Bover L, Li S. Generation of a monoclonal antibody against the glycosylphosphatidylinositol-linked protein Rae-1 using genetically engineered tumor cells. Biol Proced Online. 2014 Feb 04; 16(1):3. PMID: 24495546.
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    10. Voo KS, Bover L, Harline ML, Vien LT, Facchinetti V, Arima K, Kwak LW, Liu YJ. Antibodies targeting human OX40 expand effector T cells and block inducible and natural regulatory T cell function. J Immunol. 2013 Oct 01; 191(7):3641-50. PMID: 24014877.
      View in: PubMed
    11. Bao M, Hanabuchi S, Facchinetti V, Du Q, Bover L, Plumas J, Chaperot L, Cao W, Qin J, Sun SC, Liu YJ. CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl. J Immunol. 2012 Jul 15; 189(2):786-92. PMID: 22706086.
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    12. Talukder AH, Bao M, Kim TW, Facchinetti V, Hanabuchi S, Bover L, Zal T, Liu YJ. Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells. Cell Res. 2012 Jul; 22(7):1129-39. PMID: 22453241.
      View in: PubMed
    13. Pedroza-Gonzalez A, Xu K, Wu TC, Aspord C, Tindle S, Marches F, Gallegos M, Burton EC, Savino D, Hori T, Tanaka Y, Zurawski S, Zurawski G, Bover L, Liu YJ, Banchereau J, Palucka AK. Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J Exp Med. 2011 Mar 14; 208(3):479-90. PMID: 21339324.
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    14. Kim T, Pazhoor S, Bao M, Zhang Z, Hanabuchi S, Facchinetti V, Bover L, Plumas J, Chaperot L, Qin J, Liu YJ. Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15181-6. PMID: 20696886.
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    15. Cao W, Bover L. Signaling and ligand interaction of ILT7: receptor-mediated regulatory mechanisms for plasmacytoid dendritic cells. Immunol Rev. 2010 Mar; 234(1):163-76. PMID: 20193018.
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    16. Cao W, Bover L, Cho M, Wen X, Hanabuchi S, Bao M, Rosen DB, Wang YH, Shaw JL, Du Q, Li C, Arai N, Yao Z, Lanier LL, Liu YJ. Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction. J Exp Med. 2009 Jul 06; 206(7):1603-14. PMID: 19564354.
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    17. Voo KS, Wang YH, Santori FR, Boggiano C, Wang YH, Arima K, Bover L, Hanabuchi S, Khalili J, Marinova E, Zheng B, Littman DR, Liu YJ. Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4793-8. PMID: 19273860.
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    18. Ito T, Hanabuchi S, Wang YH, Park WR, Arima K, Bover L, Qin FX, Gilliet M, Liu YJ. Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery. Immunity. 2008 Jun; 28(6):870-80. PMID: 18513999.
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    19. Cao W, Zhang L, Rosen DB, Bover L, Watanabe G, Bao M, Lanier LL, Liu YJ. BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells. PLoS Biol. 2007 Sep 11; 5(10):e248. PMID: 17850179.
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    20. Bover LC, Cardó-Vila M, Kuniyasu A, Sun J, Rangel R, Takeya M, Aggarwal BB, Arap W, Pasqualini R. A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications. J Immunol. 2007 Jun 15; 178(12):8183-94. PMID: 17548657.
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    21. Cao W, Rosen DB, Ito T, Bover L, Bao M, Watanabe G, Yao Z, Zhang L, Lanier LL, Liu YJ. Plasmacytoid dendritic cell-specific receptor ILT7-Fc epsilonRI gamma inhibits Toll-like receptor-induced interferon production. J Exp Med. 2006 Jun 12; 203(6):1399-405. PMID: 16735691.
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    22. Kolonin MG, Bover L, Sun J, Zurita AJ, Do KA, Lahdenranta J, Cardó-Vila M, Giordano RJ, Jaalouk DE, Ozawa MG, Moya CA, Souza GR, Staquicini FI, Kunyiasu A, Scudiero DA, Holbeck SL, Sausville EA, Arap W, Pasqualini R. Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries. Cancer Res. 2006 Jan 01; 66(1):34-40. PMID: 16397212.
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    23. Mantegazza AR, Barrio MM, Moutel S, Bover L, Weck M, Brossart P, Teillaud JL, Mordoh J. CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells. Blood. 2004 Aug 15; 104(4):1183-90. PMID: 15130945.
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    24. Capurro M, Ballaré C, Bover L, Portela P, Mordoh J. Differential lytic and agglutinating activity of the anti-Lewis(x) monoclonal antibody FC-2.15 on human polymorphonuclear neutrophils and MCF-7 breast tumor cells. In vitro and ex vivo studies. Cancer Immunol Immunother. 1999 May-Jun; 48(2-3):100-8. PMID: 10414463.
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    25. Bover L, Barrio M, Bravo AI, Slavutsky I, Larripa I, Bolondi A, Ayala M, Mordoh J. The human breast cancer cell line IIB-BR-G has amplified c-myc and c-fos oncogenes in vitro and is spontaneously metastatic in vivo. Cell Mol Biol (Noisy-le-grand). 1998 May; 44(3):493-504. PMID: 9620446.
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    26. Capurro M, Bover L, Portela P, Livingston P, Mordoh J. FC-2.15, a monoclonal antibody active against human breast cancer, specifically recognizes Lewis(x) hapten. Cancer Immunol Immunother. 1998 Feb; 45(6):334-9. PMID: 9490204.
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    27. Ledda F, Bravo AI, Adris S, Bover L, Mordoh J, Podhajcer OL. The expression of the secreted protein acidic and rich in cysteine (SPARC) is associated with the neoplastic progression of human melanoma. J Invest Dermatol. 1997 Feb; 108(2):210-4. PMID: 9008236.
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    28. Ledda MF, Adris S, Bravo AI, Kairiyama C, Bover L, Chernajovsky Y, Mordoh J, Podhajcer OL. Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells. Nat Med. 1997 Feb; 3(2):171-6. PMID: 9018235.
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    29. Mordoh J, Kairiyama C, Bover L, Solarolo E. Allogeneic cells vaccine increases disease-free survival in stage III melanoma patients. A non randomized phase II study. Medicina (B Aires). 1997; 57(4):421-7. PMID: 9674264.
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    30. Ledda MF, Adris S, Bravo AI, Bover L, Carbone C, Paleolog E, Mordoh J, Chernajovsky Y, Podhajcer OL. Tumor cells engineered to express interleukin-6 exhibit a reduced tumorigenicity depending on the tumor cell model. Cell Mol Biol (Noisy-le-grand). 1996 Jul; 42(5):769-78. PMID: 8832108.
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    31. Morvillo V, Bover L, Mordoh J. Identification and characterization of a 14 kDa immunosuppressive protein derived from IIB-MEL-J, a human melanoma cell line. Cell Mol Biol (Noisy-le-grand). 1996 Jul; 42(5):779-95. PMID: 8832109.
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    32. Ledda MF, Adris S, Bover L, Bravo AL, Mordoh J, Podhajcer OL. [The role of SPARC gene in tumorigenic capacity of human melanoma cells]. Medicina (B Aires). 1996; 56(1):51-4. PMID: 8734932.
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    33. Kairiyama C, Slavutsky I, Larripa I, Morvillo V, Bravo AI, Bover L, Podhajcer OL, Mordoh J. Biologic, immunocytochemical, and cytogenetic characterization of two new human melanoma cell lines: IIB-MEL-LES and IIB-MEL-IAN. Pigment Cell Res. 1995 Jun; 8(3):121-31. PMID: 7567787.
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    34. Podhajcer OL, Bover L, Bravo AI, Ledda MF, Kairiyama C, Calb I, Guerra L, Capony F, Mordoh J. Expression of cathepsin D in primary and metastatic human melanoma and dysplastic nevi. J Invest Dermatol. 1995 Mar; 104(3):340-4. PMID: 7860998.
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    35. Mordoh J, Leis S, Bravo AI, Podhajcer OL, Ballare C, Capurro M, Kairiyama C, Bover L. Description of a new monoclonal antibody, FC-2.15, reactive with human breast cancer and other human neoplasias. Int J Biol Markers. 1994 Jul-Sep; 9(3):125-34. PMID: 7829891.
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    36. Bover L, Barrio M, Slavutsky I, Bravo AI, Quintans C, Bagnati A, Lema B, Schiaffi J, Yomha R, Mordoh J. Description of a new human breast cancer cell line, IIB-BR-G, established from a primary undifferentiated tumor. Breast Cancer Res Treat. 1991 Sep; 19(1):47-56. PMID: 1661624.
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    37. Guerra L, Bover L, Mordoh J. Differentiating effect of L-tyrosine on the human melanoma cell line IIB-MEL-J. Exp Cell Res. 1990 May; 188(1):61-5. PMID: 2328778.
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    38. Medrano EE, Resnicoff M, Cafferata EG, Larcher F, Podhajcer O, Bover L, Molinari B. Increased secretory activity and estradiol receptor expression are among other relevant aspects of MCF-7 human breast tumor cell growth which are expressed only in the absence of serum. Exp Cell Res. 1990 May; 188(1):2-9. PMID: 2184046.
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    39. Podhajcer OL, Resnicoff M, Bover L, Medrano EE, Slavutsky I, Larripa I, Mordoh J. Effect of estradiol and tamoxifen on the anchorage-independent growth of the subpopulations derived from MCF-7 breast carcinoma cells: cytogenetic analysis of the stem cell subpopulation. Exp Cell Res. 1988 Nov; 179(1):58-64. PMID: 3169151.
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    40. Podhajcer OL, Bravo AI, Dain L, Guman N, Bover L, Mordoh J. In vitro analysis of the cellular proliferative response to 17-beta-estradiol of human breast cancer. Cancer. 1988 May 01; 61(9):1807-12. PMID: 3281743.
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    41. Resnicoff M, Medrano EE, Podhajcer OL, Bravo AI, Bover L, Mordoh J. Subpopulations of MCF7 cells separated by Percoll gradient centrifugation: a model to analyze the heterogeneity of human breast cancer. Proc Natl Acad Sci U S A. 1987 Oct; 84(20):7295-9. PMID: 2823256.
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    42. Cabral S, Leis S, Bover L, Nembrot M, Mordoh J. Dipyridamole inhibits reversion by thymidine of methotrexate effect and increases drug uptake in Sarcoma 180 cells. Proc Natl Acad Sci U S A. 1984 May; 81(10):3200-3. PMID: 6587345.
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    43. Platelet-activating factor induces cell cycle arrest and disrupts the DNA damage response in mast cells. Cell Death and Disease. 6.
    44. Tumor imaging with 99mTc-labeled FC-5.01 monoclonal antibody using a single step labeling method. Journal of Radioanalytical and Nuclear Chemistry. 245:337-341.
    45. Biological aspects of human plasmacytoid dendritic cells and their leukemic counterparts; similarities and differences. Inmunologia. 29:125-134.
    46. New blocking antibodies against novel AGR2-C4.4A pathway reduce growth and metastasis of pancreatic tumors and increase survival in mice. Molecular Cancer Therapeutics. 14:941-951.
    47. Targeting IL11 receptor in leukemia and lymphoma. Clinical Cancer Research. 21:3041-3051.
    48. Analysis of DNA synthesis and carcinoembryonic antigen expression in human breast cancer. Journal of Experimental and Clinical Cancer Research. 7:35-42.
    49. Generation of a monoclonal antibody against the glycosylphosphatidylinositol-linked protein Rae-1 using genetically engineered tumor cells. Biological Procedures Online. 16.
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