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HESHAM AMIN

TitleProfessor
InstitutionMD Anderson
DepartmentHematopathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chamseddine S, LaPelusa M, Xiao L, Mohamed YI, Lee SS, Hu ZI, Hatia RI, Hassan M, Yao JC, Duda DG, Datar S, Amin HM, Kaseb AO. Plasma Growth Hormone as a Prognostic Biomarker to Durvalumab and Tremelimumab in Patients with Advanced Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2024; 11:455-461. PMID: 38463542; PMCID: PMC10921889.
      Citations:    
    2. Hassan MM, Li D, Han Y, Byun J, Hatia RI, Long E, Choi J, Kelley RK, Cleary SP, Lok AS, Bracci P, Permuth JB, Bucur R, Yuan JM, Singal AG, Jalal PK, Ghobrial RM, Santella RM, Kono Y, Shah DP, Nguyen MH, Liu G, Parikh ND, Kim R, Wu HC, El-Serag H, Chang P, Li Y, Chun YS, Lee SS, Gu J, Hawk E, Sun R, Huff C, Rashid A, Amin HM, Beretta L, Wolff RA, Antwi SO, Patt Y, Hwang LY, Klein AP, Zhang K, Schmidt MA, White DL, Goss JA, Khaderi SA, Marrero JA, Cigarroa FG, Shah PK, Kaseb AO, Roberts LR, Amos CI. Genome-wide association study identifies high-impact susceptibility loci for hepatocellular carcinoma in North America. Hepatology. 2024 Feb 20. PMID: 38381705.
      Citations:    Fields:    
    3. Gok Yavuz B, Datar S, Chamseddine S, Mohamed YI, LaPelusa M, Lee SS, Hu ZI, Koay EJ, Tran Cao HS, Jalal PK, Daniel-MacDougall C, Hassan M, Duda DG, Amin HM, Kaseb AO. The Gut Microbiome as a Biomarker and Therapeutic Target in Hepatocellular Carcinoma. Cancers (Basel). 2023 Oct 07; 15(19). PMID: 37835569; PMCID: PMC10571776.
      Citations:    
    4. Lou J, Geng S, He W, Liu SB, Shi X, Chang Y, Han S, Qian P, Amin HM, Song YH, Li Y, Zhou J. Zyxin inhibits the epithelial-mesenchymal transition process in gastric cancer by upregulating SIRT1. MedComm (2020). 2023 Oct; 4(5):e357. PMID: 37667739; PMCID: PMC10475219.
      Citations:    
    5. Chamseddine S, Mohamed YI, Lee SS, Yao JC, Hu ZI, Tran Cao HS, Xiao L, Sun R, Morris JS, Hatia RI, Hassan M, Duda DG, Diab M, Mohamed A, Nassar A, Datar S, Amin HM, Kaseb AO. Clinical and Prognostic Biomarker Value of Blood-Circulating Inflammatory Cytokines in Hepatocellular Carcinoma. Oncology. 2023; 101(11):730-737. PMID: 37467732; PMCID: PMC10614568.
      Citations:    Fields:    Translation:Humans
    6. George B, George SK, Shi W, Haque A, Shi P, Eskandari G, Axelson M, Larsson O, Kaseb AO, Amin HM. Correction: Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK+ T-cell lymphoma. J Hematol Oncol. 2023 Jun 13; 16(1):61. PMID: 37312210; PMCID: PMC10265893.
      Citations:    Fields:    
    7. Mohamed YI, Duda DG, Awiwi MO, Lee SS, Altameemi L, Xiao L, Morris JS, Wolff RA, Elsayes KM, Hatia RI, Qayyum A, Chamseddine SM, Rashid A, Yao JC, Mahvash A, Hassan MM, Amin HM, Kaseb AO. Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients. Oncotarget. 2022 12 06; 13:1314-1321. PMID: 36473155; PMCID: PMC9726202.
      Citations: 1     Fields:    Translation:Humans
    8. Kaseb AO, Haque A, Vishwamitra D, Hassan MM, Xiao L, George B, Sahu V, Mohamed YI, Carmagnani Pestana R, Lombardo JL, Avritscher R, Yao JC, Wolff RA, Rashid A, Morris JS, Amin HM. Blockade of growth hormone receptor signaling by using pegvisomant: A functional therapeutic strategy in hepatocellular carcinoma. Front Oncol. 2022; 12:986305. PMID: 36276070; PMCID: PMC9582251.
      Citations: 1     
    9. Haque A, Sahu V, Lombardo JL, Xiao L, George B, Wolff RA, Morris JS, Rashid A, Kopchick JJ, Kaseb AO, Amin HM. Disruption of Growth Hormone Receptor Signaling Abrogates Hepatocellular Carcinoma Development. J Hepatocell Carcinoma. 2022; 9:823-837. PMID: 35996397; PMCID: PMC9391993.
      Citations:    
    10. George B, Haque A, Sahu V, Joldoshova A, Singh Y, Quinones JE, George SK, Amin HM. Enhancing Antigen Retrieval to Unmask Signaling Phosphoproteins in Formalin-fixed Archival Tissues. Appl Immunohistochem Mol Morphol. 2022 May-Jun 01; 30(5):333-339. PMID: 35510772; PMCID: PMC9096965.
      Citations:    Fields:    Translation:HumansAnimals
    11. Wang Z, Kaseb AO, Amin HM, Hassan MM, Wang W, Morris JS. Bayesian Edge Regression in Undirected Graphical Models to Characterize Interpatient Heterogeneity in Cancer. J Am Stat Assoc. 2022; 117(538):533-546. PMID: 36090952; PMCID: PMC9454401.
      Citations:    
    12. Jan T, Gul S, Khan A, Pervez S, Noor A, Amin H, Bibi S, Nawaz MA, Rahim A, Ahmad MS, Azam R, Ullah H. Range of factors in the reduction of hyperhydricity associated with in vitro shoots of Salvia santolinifolia Bioss. Braz J Biol. 2021; 83:e246904. PMID: 34706025.
      Citations:    Fields:    Translation:Animals
    13. Subbiah V, Kuravi S, Ganguly S, Welch DR, Vivian CJ, Mushtaq MU, Hegde A, Iyer S, Behrang A, Ali SM, Madison RW, Venstrom JM, Jensen RA, McGuirk JP, Amin HM, Balusu R. Precision therapy with anaplastic lymphoma kinase inhibitor ceritinib in ALK-rearranged anaplastic large cell lymphoma. ESMO Open. 2021 08; 6(4):100172. PMID: 34242968; PMCID: PMC8271116.
      Citations: 1     Translation:Humans
    14. Morris JS, Hassan MM, Zohner YE, Wang Z, Xiao L, Rashid A, Haque A, Abdel-Wahab R, Mohamed YI, Ballard KL, Wolff RA, George B, Li L, Allen G, Weylandt M, Li D, Wang W, Raghav K, Yao J, Amin HM, Kaseb AO. HepatoScore-14: Measures of Biological Heterogeneity Significantly Improve Prediction of Hepatocellular Carcinoma Risk. Hepatology. 2021 06; 73(6):2278-2292. PMID: 32931023; PMCID: PMC7956911.
      Citations: 1     Fields:    Translation:Humans
    15. Morris JS, Hassan M, Amin H, Kaseb A. REPLY. Hepatology. 2021 06; 73(6):2612. PMID: 33170975.
      Citations:    Fields:    
    16. Morris JS, Hassan M, Amin H, Kaseb A. REPLY. Hepatology. 2021 06; 73(6):2614. PMID: 33171542.
      Citations:    Fields:    
    17. Mohamed YI, Lee S, Xiao L, Hassan MM, Qayyum A, Hiatia R, Pestana RC, Haque A, George B, Rashid A, Duda DG, Elghazaly H, Wolff RA, Morris JS, Yao J, Amin HM, Kaseb AO. Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib. Oncotarget. 2021 Apr 13; 12(8):756-766. PMID: 33889299; PMCID: PMC8057275.
      Citations: 1     Fields:    
    18. Abdel-Wahab R, Hassan MM, George B, Carmagnani Pestana R, Xiao L, Lacin S, Yalcin S, Shalaby AS, Al-Shamsi HO, Raghav K, Wolff RA, Yao JC, Girard L, Haque A, Duda DG, Dima S, Popescu I, Elghazaly HA, Vauthey JN, Aloia TA, Tzeng CW, Chun YS, Rashid A, Morris JS, Amin HM, Kaseb AO. Impact of Integrating Insulin-Like Growth Factor 1 Levels into Model for End-Stage Liver Disease Score for Survival Prediction in Hepatocellular Carcinoma Patients. Oncology. 2020; 98(12):836-846. PMID: 33027788; PMCID: PMC7704605.
      Citations: 2     Fields:    Translation:Humans
    19. Lacin S, Yalcin S, Karakas Y, Hassan MM, Amin H, Mohamed YI, Rashid A, Morris JS, Xiao L, Qayyum A, Kaseb AO. Prognostic Significance of Serum Insulin-Like Growth Factor-1 in Hepatocellular Cancer Patients: A Validation Study. J Hepatocell Carcinoma. 2020; 7:143-153. PMID: 32984091; PMCID: PMC7502406.
      Citations: 1     
    20. Wang B, Zheng J, Chen Q, Wu C, Li Y, Yu XY, Liu B, Liang C, Liu SB, Ding H, Wang S, Xue T, Song D, Lei Z, Amin HM, Song YH, Zhou J. CLIC4 abrogation promotes epithelial-mesenchymal transition in gastric cancer. Carcinogenesis. 2020 07 10; 41(6):841-849. PMID: 31560739.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    21. Amin HM, Morani AC, Daw NC, Lamhamedi-Cherradi SE, Subbiah V, Menegaz BA, Vishwamitra D, Eskandari G, George B, Benjamin RS, Patel S, Song J, Lazar AJ, Wang WL, Kurzrock R, Pappo A, Anderson PM, Schwartz GK, Araujo D, Cuglievan B, Ratan R, McCall D, Mohiuddin S, Livingston JA, Molina ER, Naing A, Ludwig JA. IGF-1R/mTOR Targeted Therapy for Ewing Sarcoma: A Meta-Analysis of Five IGF-1R-Related Trials Matched to Proteomic and Radiologic Predictive Biomarkers. Cancers (Basel). 2020 Jul 02; 12(7). PMID: 32630797; PMCID: PMC7408058.
      Citations: 10     
    22. Yavuz BG, Pestana RC, Abugabal YI, Krishnan S, Chen J, Hassan MM, Wolff RA, Rashid A, Amin HM, Kaseb AO. Origin and role of hepatic myofibroblasts in hepatocellular carcinoma. Oncotarget. 2020 Mar 31; 11(13):1186-1201. PMID: 32284794; PMCID: PMC7138168.
      Citations: 9     Fields:    
    23. Wu C, Ding H, Wang S, Li Y, Liu SB, Wang X, Zheng J, Xue T, Amin HM, Song YH, Zhou J. DAXX inhibits cancer stemness and epithelial-mesenchymal transition in gastric cancer. Br J Cancer. 2020 05; 122(10):1477-1485. PMID: 32203224; PMCID: PMC7217831.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    24. Falchook GS, Kurzrock R, Amin HM, Xiong W, Fu S, Piha-Paul SA, Janku F, Eskandari G, Catenacci DV, Klevesath M, Bruns R, Stammberger U, Johne A, Bladt F, Friese-Hamim M, Girard P, El Bawab S, Hong DS. First-in-Man Phase I Trial of the Selective MET Inhibitor Tepotinib in Patients with Advanced Solid Tumors. Clin Cancer Res. 2020 03 15; 26(6):1237-1246. PMID: 31822497.
      Citations: 24     Fields:    Translation:HumansCTClinical Trials
    25. Qayyum A, Hwang KP, Stafford J, Verma A, Maru DM, Sandesh S, Sun J, Pestana RC, Avritscher R, Hassan MM, Amin H, Rashid A, Wistuba II, Ehman RL, Ma J, Kaseb AO. Immunotherapy response evaluation with magnetic resonance elastography (MRE) in advanced HCC. J Immunother Cancer. 2019 11 28; 7(1):329. PMID: 31779702; PMCID: PMC6883599.
      Citations: 12     Fields:    Translation:HumansCells
    26. Kaseb AO, Sen S, Kelley RK, Tan B, Bocobo AG, Lim KH, Abdel-Wahab R, Uemura M, Pestana RC, Qiao W, Xiao L, Morris J, Amin HM, Hassan MM, Rashid A, Banks KC, Lanman RB, Talasaz A, Mills-Shaw KR, George B, Haque A, Raghav KPS, Wolff RA, Yao JC, Meric-Bernstam F, Ikeda S, Kurzrock R, S?nchez NS. Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA. Clin Cancer Res. 2019 10 15; 25(20):6107-6118. PMID: 31363003; PMCID: PMC9292132.
      Citations: 27     Fields:    Translation:Humans
    27. George B, George SK, Shi W, Haque A, Shi P, Eskandari G, Axelson M, Larsson O, Kaseb AO, Amin HM. Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK+ T-cell lymphoma. J Hematol Oncol. 2019 07 24; 12(1):80. PMID: 31340850; PMCID: PMC6657048.
      Citations: 8     Fields:    Translation:Humans
    28. Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC. IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion. J Clin Invest. 2019 07 15; 129(8):3324-3338. PMID: 31305264; PMCID: PMC6668668.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    29. Pestana RC, Hassan MM, Abdel-Wahab R, Abugabal YI, Girard LM, Li D, Chang P, Raghav K, Morris J, Wolff RA, Rashid A, Amin HM, Kaseb A. Clinical and prognostic significance of circulating levels of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma. Oncotarget. 2018 Dec 28; 9(102):37721-37732. PMID: 30701027; PMCID: PMC6340869.
      Citations: 7     Fields:    
    30. Kurt H, Jorgensen JL, Amin HM, Patel KP, Wang SA, Lin P, Kanagal-Shamanna R, Loghavi S, Thakral B, Khogeer HA, Jabbour EJ, Li S, Yin CC, Medeiros LJ, Khoury JD. Chronic lymphoproliferative disorder of NK-cells: A single-institution review with emphasis on relative utility of multimodality diagnostic tools. Eur J Haematol. 2018 May; 100(5):444-454. PMID: 29385279.
      Citations: 8     Fields:    Translation:HumansCells
    31. Kurt H, Zheng L, Kantarjian HM, Tang G, Ravandi-Kashani F, Garcia-Manero G, Gong Z, Amin HM, Konoplev SN, Routbort MJ, Han X, Wang W, Medeiros LJ, Hu S. Secondary Philadelphia chromosome acquired during therapy of acute leukemia and myelodysplastic syndrome. Mod Pathol. 2018 07; 31(7):1141-1154. PMID: 29449681.
      Citations: 5     Fields:    Translation:HumansCells
    32. Hu L, Zhang X, Wang J, Wang S, Shi P, Amin HM. Involvement of oncogenic tyrosine kinase NPM-ALK in trifluoperazine-induced cell cycle arrest and apoptosis in ALK+ anaplastic large cell lymphoma. Hematology. 2018 Jun; 23(5):284-290. PMID: 29086626.
      Citations: 2     Fields:    Translation:HumansCells
    33. Liu Y, Zhu S, Gu K, Guo Z, Huang X, Wang M, Amin HM, Zhu W, Shi P. GSH-Activated NIR Fluorescent Prodrug for Podophyllotoxin Delivery. ACS Appl Mater Interfaces. 2017 Sep 06; 9(35):29496-29504. PMID: 28758393.
      Citations: 4     Fields:    Translation:AnimalsCells
    34. Shen C, Song YH, Xie Y, Wang X, Wang Y, Wang C, Liu S, Xue SL, Li Y, Liu B, Tang Z, Chen W, Song J, Amin HM, Zhou J. Downregulation of HADH promotes gastric cancer progression via Akt signaling pathway. Oncotarget. 2017 Sep 29; 8(44):76279-76289. PMID: 29100311; PMCID: PMC5652705.
      Citations: 5     Fields:    
    35. Al-Shamsi HO, Abdel-Wahab R, Hassan MM, Shalaby AS, Dahbour I, Lacin S, Mahvash A, Odisio BC, Murthy R, Avritscher R, Abdelsalam ME, Rashid A, Vauthey JN, Aloia TA, Conrad C, Chun YS, Krishnan S, Das P, Koay EJ, Amin HM, Yao JC, Kaseb AO. Natural History of T1N0M0 Hepatocellular Carcinoma: Large-Scale Study in the United States. Oncology. 2017; 93(4):233-242. PMID: 28683459; PMCID: PMC6743737.
      Citations: 1     Fields:    Translation:Humans
    36. Shi W, George SK, George B, Curry CV, Murzabdillaeva A, Alkan S, Amin HM. TrkA is a binding partner of NPM-ALK that promotes the survival of ALK+ T-cell lymphoma. Mol Oncol. 2017 09; 11(9):1189-1207. PMID: 28557340; PMCID: PMC5579389.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    37. Vishwamitra D, George SK, Shi P, Kaseb AO, Amin HM. Type I insulin-like growth factor receptor signaling in hematological malignancies. Oncotarget. 2017 Jan 03; 8(1):1814-1844. PMID: 27661006; PMCID: PMC5352101.
      Citations: 18     Fields:    Translation:HumansCells
    38. Mohanty A, Sandoval N, Das M, Pillai R, Chen L, Chen RW, Amin HM, Wang M, Marcucci G, Weisenburger DD, Rosen ST, Pham LV, Ngo VN. CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma. Oncotarget. 2016 Nov 08; 7(45):73558-73572. PMID: 27713153; PMCID: PMC5341999.
      Citations: 23     Fields:    Translation:HumansCells
    39. Kaseb AO, Hassan M, Lacin S, Abdel-Wahab R, Amin HM, Shalaby A, Wolff RA, Yao J, Rashid A, Vennapusa B, Feng J, Ohtomo T. Evaluating clinical and prognostic implications of Glypican-3 in hepatocellular carcinoma. Oncotarget. 2016 Oct 25; 7(43):69916-69926. PMID: 27655712; PMCID: PMC5342524.
      Citations: 23     Fields:    Translation:Humans
    40. Lamhamedi-Cherradi SE, Menegaz BA, Ramamoorthy V, Vishwamitra D, Wang Y, Maywald RL, Buford AS, Fokt I, Skora S, Wang J, Naing A, Lazar AJ, Rohren EM, Daw NC, Subbiah V, Benjamin RS, Ratan R, Priebe W, Mikos AG, Amin HM, Ludwig JA. IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma. J Natl Cancer Inst. 2016 12; 108(12). PMID: 27576731; PMCID: PMC5241894.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    41. Raghav K, Morris V, Tang C, Morelli P, Amin HM, Chen K, Manyam GC, Broom B, Overman MJ, Shaw K, Meric-Bernstam F, Maru D, Menter D, Ellis LM, Eng C, Hong D, Kopetz S. MET amplification in metastatic colorectal cancer: an acquired response to EGFR inhibition, not a de novo phenomenon. Oncotarget. 2016 08 23; 7(34):54627-54631. PMID: 27421137; PMCID: PMC5342368.
      Citations: 23     Fields:    Translation:Humans
    42. Hu LL, Zhen H, Zhang XN, Zhou L, Amin HM, Shi P. [Effect of Tyrosine Phosphorylation Sites of Oncogenic Protein NPM-ALK on Cell Cycle and Its Related Mechanisms]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016 Aug; 24(4):1201-5. PMID: 27531800.
      Citations:    Fields:    Translation:HumansCells
    43. Mitchell J, Tinkey PT, Avritscher R, Van Pelt C, Eskandari G, Konnath George S, Xiao L, Cressman E, Morris JS, Rashid A, Kaseb AO, Amin HM, Uthamanthil R. Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs. Oncology. 2016; 91(2):90-100. PMID: 27305144; PMCID: PMC5432216.
      Citations: 10     Fields:    Translation:Animals
    44. Abdel-Wahab R, Shehata S, Hassan MM, Habra MA, Eskandari G, Tinkey PT, Mitchell J, Lee JS, Amin HM, Kaseb AO. Type I insulin-like growth factor as a liver reserve assessment tool in hepatocellular carcinoma. J Hepatocell Carcinoma. 2015; 2:131-42. PMID: 27508202; PMCID: PMC4918293.
      Citations: 7     
    45. Irwin ME, Johnson BP, Manshouri R, Amin HM, Chandra J. A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies. Oncotarget. 2015 Sep 15; 6(27):23631-46. PMID: 26136341; PMCID: PMC4695141.
      Citations: 9     Fields:    Translation:HumansCells
    46. Vishwamitra D, Curry CV, Shi P, Alkan S, Amin HM. SUMOylation Confers Posttranslational Stability on NPM-ALK Oncogenic Protein. Neoplasia. 2015 Sep; 17(9):742-754. PMID: 26476082; PMCID: PMC4611074.
      Citations: 8     Fields:    Translation:HumansCells
    47. Abdel-Wahab R, Shehata S, Hassan MM, Xiao L, Lee JS, Cheung S, Essa HH, Hassabo HM, Shalaby AS, Mosad E, Raghav K, Rashid A, Wolff RA, Morris JS, Amin HM, Kaseb AO. Validation of an IGF-CTP scoring system for assessing hepatic reserve in Egyptian patients with hepatocellular carcinoma. Oncotarget. 2015 Aug 28; 6(25):21193-207. PMID: 26098859; PMCID: PMC4673259.
      Citations: 7     Fields:    Translation:Humans
    48. Wang W, Cortes JE, Lin P, Beaty MW, Ai D, Amin HM, McDonnell TJ, Ok CY, Kantarjian HM, Medeiros LJ, Hu S. Clinical and prognostic significance of 3q26.2 and other chromosome 3 abnormalities in CML in the era of tyrosine kinase inhibitors. Blood. 2015 Oct 01; 126(14):1699-706. PMID: 26243778; PMCID: PMC4624442.
      Citations: 17     Fields:    Translation:HumansCells
    49. Yang L, Zhang S, George SK, Teng R, You X, Xu M, Liu H, Sun X, Amin HM, Shi W. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015 Jun 20; 6(17):14953-69. PMID: 25879451; PMCID: PMC4558128.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    50. Vishwamitra D, Curry CV, Alkan S, Song YH, Gallick GE, Kaseb AO, Shi P, Amin HM. The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK? T-cell lymphoma. Mol Cancer. 2015 Feb 25; 14:53. PMID: 25884514; PMCID: PMC4415347.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    51. Falchook GS, Wheler JJ, Naing A, Jackson EF, Janku F, Hong D, Ng CS, Tannir NM, Lawhorn KN, Huang M, Angelo LS, Vishwamitra D, Hess K, Howard AN, Parkhurst KL, Amin HM, Kurzrock R. Targeting hypoxia-inducible factor-1a (HIF-1a) in combination with antiangiogenic therapy: a phase I trial of bortezomib plus bevacizumab. Oncotarget. 2014 Nov 15; 5(21):10280-92. PMID: 25373733; PMCID: PMC4279372.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    52. Li J, Kurasawa Y, Wang Y, Clise-Dwyer K, Klumpp SA, Liang H, Tailor RC, Raymond AC, Estrov Z, Brandt SJ, Davis RE, Zweidler-McKay P, Amin HM, Nagarajan L. Requirement for ssbp2 in hematopoietic stem cell maintenance and stress response. J Immunol. 2014 Nov 01; 193(9):4654-62. PMID: 25238756; PMCID: PMC4201964.
      Citations: 8     Fields:    Translation:AnimalsCells
    53. Lamhamedi-Cherradi SE, Santoro M, Ramammoorthy V, Menegaz BA, Bartholomeusz G, Iles LR, Amin HM, Livingston JA, Mikos AG, Ludwig JA. 3D tissue-engineered model of Ewing's sarcoma. Adv Drug Deliv Rev. 2014 Dec 15; 79-80:155-71. PMID: 25109853; PMCID: PMC4397982.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    54. George SK, Vishwamitra D, Manshouri R, Shi P, Amin HM. The ALK inhibitor ASP3026 eradicates NPM-ALK? T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget. 2014 Jul 30; 5(14):5750-63. PMID: 25026277; PMCID: PMC4170597.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    55. Ma H, Mallampati S, Lu Y, Sun B, Wang E, Leng X, Gong Y, Shen H, Yin CC, Jones D, Amin HM, You MJ, Zweidler-McKay P, Ma Y, Kantarjian HM, Arlinghaus RB, Glassman A, Sun X. The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia. Haematologica. 2014 Oct; 99(10):1591-8. PMID: 24997151; PMCID: PMC4181255.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    56. Yue Y, Wang Y, He Y, Yang S, Chen Z, Wang Y, Xing S, Shen C, Amin HM, Wu D, Song YH. Reversal of bortezomib resistance in myelodysplastic syndrome cells by MAPK inhibitors. PLoS One. 2014; 9(3):e90992. PMID: 24608798; PMCID: PMC3946707.
      Citations: 1     Fields:    Translation:HumansCells
    57. Ok CY, Wang SA, Amin HM. Leukemic phase of ALK(+) anaplastic large-cell lymphoma, small-cell variant: clinicopathologic pitfalls of a rare entity. Clin Lymphoma Myeloma Leuk. 2014 Aug; 14(4):e123-6. PMID: 24685107.
      Citations: 1     Fields:    Translation:HumansCells
    58. Huang Z, Fang Z, Zhen H, Zhou L, Amin HM, Shi P. Inhibition of type I insulin-like growth factor receptor tyrosine kinase by picropodophyllin induces apoptosis and cell cycle arrest in T lymphoblastic leukemia/lymphoma. Leuk Lymphoma. 2014 Aug; 55(8):1876-83. PMID: 24206093; PMCID: PMC4386890.
      Citations: 5     Fields:    Translation:HumansCells
    59. Hamedani FS, Cinar M, Mo Z, Cervania MA, Amin HM, Alkan S. Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell lymphoma. Leuk Res. 2014 Apr; 38(4):503-8. PMID: 24486291; PMCID: PMC4386887.
      Citations: 13     Fields:    Translation:HumansCells
    60. Kamiya-Matsuoka C, Garciarena P, Amin HM, Tremont-Lukats IW, de Groot JF. B lymphoblastic leukemia/lymphoma presenting as seventh cranial nerve palsy. Neurol Clin Pract. 2013 Dec; 3(6):532-534. PMID: 30107017; PMCID: PMC6082360.
      Citations:    
    61. Cinar M, Hamedani F, Mo Z, Cinar B, Amin HM, Alkan S. Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis. Leuk Res. 2013 Oct; 37(10):1271-7. PMID: 23962569.
      Citations: 47     Fields:    Translation:HumansCells
    62. Shi B, Vishwamitra D, Granda JG, Whitton T, Shi P, Amin HM. Molecular and functional characterizations of the association and interactions between nucleophosmin-anaplastic lymphoma kinase and type I insulin-like growth factor receptor. Neoplasia. 2013 Jun; 15(6):669-83. PMID: 23730215; PMCID: PMC3664999.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    63. Liu J, Chen G, Feng L, Zhang W, Pelicano H, Wang F, Ogasawara MA, Lu W, Amin HM, Croce CM, Keating MJ, Huang P. Loss of p53 and altered miR15-a/16-1?MCL-1 pathway in CLL: insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells. Leukemia. 2014 Jan; 28(1):118-28. PMID: 23608884; PMCID: PMC3806892.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    64. Fong EL, Lamhamedi-Cherradi SE, Burdett E, Ramamoorthy V, Lazar AJ, Kasper FK, Farach-Carson MC, Vishwamitra D, Demicco EG, Menegaz BA, Amin HM, Mikos AG, Ludwig JA. Modeling Ewing sarcoma tumors in vitro with 3D scaffolds. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6500-5. PMID: 23576741; PMCID: PMC3631678.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    65. Zhu H, Vishwamitra D, Curry CV, Manshouri R, Diao L, Khan A, Amin HM. NPM-ALK up-regulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism. J Pathol. 2013 May; 230(1):82-94. PMID: 23338972; PMCID: PMC3940725.
      Citations: 12     Fields:    Translation:HumansCells
    66. Jain P, Verstovsek S, Orlowski RZ, Yap E, Amin HM. An unusual case of aggressive systemic mastocytosis with associated refractory plasma cell myeloma. Clin Lymphoma Myeloma Leuk. 2012 Dec; 12(6):459-62. PMID: 23009979.
      Citations: 1     Fields:    Translation:Humans
    67. Vishwamitra D, Li Y, Wilson D, Manshouri R, Curry CV, Shi B, Tang XM, Sheehan AM, Wistuba II, Shi P, Amin HM. MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression. Am J Pathol. 2012 May; 180(5):1772-80. PMID: 22414602; PMCID: PMC3349824.
      Citations: 28     Fields:    Translation:HumansCells
    68. Singh MM, Irwin ME, Gao Y, Ban K, Shi P, Arlinghaus RB, Amin HM, Chandra J. Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia. Cancer. 2012 Jul 01; 118(13):3433-45. PMID: 22139798; PMCID: PMC3297684.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    69. Vishwamitra D, Shi P, Wilson D, Manshouri R, Vega F, Schlette EJ, Amin HM. Expression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma. Haematologica. 2011 Jun; 96(6):871-80. PMID: 21330319; PMCID: PMC3105649.
      Citations: 15     Fields:    Translation:HumansCells
    70. Janku F, Amin HM, Yang D, Garrido-Laguna I, Trent JC, Kurzrock R. Response of histiocytoses to imatinib mesylate: fire to ashes. J Clin Oncol. 2010 Nov 01; 28(31):e633-6. PMID: 20733125.
      Citations: 17     Fields:    Translation:Humans
    71. Wang Y, Klumpp S, Amin HM, Liang H, Li J, Estrov Z, Zweidler-McKay P, Brandt SJ, Agulnick A, Nagarajan L. SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability. Oncogene. 2010 May 27; 29(21):3044-53. PMID: 20348955; PMCID: PMC2878399.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    72. Singh RR, Kim JE, Davuluri Y, Drakos E, Cho-Vega JH, Amin HM, Vega F. Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation. Leukemia. 2010 May; 24(5):1025-36. PMID: 20200556.
      Citations: 38     Fields:    Translation:HumansCells
    73. Amin HM, Kantarjian H, Verstovsek S, Quint?s-Cardama A. Treatment of aggressive systemic mastocytosis with daclizumab. Leuk Lymphoma. 2010 Mar; 51(3):540-2. PMID: 20038223.
      Citations: 3     Fields:    Translation:Humans
    74. Dien Bard J, Gelebart P, Anand M, Zak Z, Hegazy SA, Amin HM, Lai R. IL-21 contributes to JAK3/STAT3 activation and promotes cell growth in ALK-positive anaplastic large cell lymphoma. Am J Pathol. 2009 Aug; 175(2):825-34. PMID: 19608866; PMCID: PMC2716977.
      Citations: 27     Fields:    Translation:HumansCells
    75. Lakshmikuttyamma A, Takahashi N, Pastural E, Torlakovic E, Amin HM, Garcia-Manero G, Voralia M, Czader M, DeCoteau JF, Geyer CR. RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression. J Hematol Oncol. 2009 Jul 14; 2:28. PMID: 19602237; PMCID: PMC2719666.
      Citations: 9     Fields:    Translation:HumansCells
    76. Shi P, Chandra J, Sun X, Gergely M, Cortes JE, Garcia-Manero G, Arlinghaus RB, Lai R, Amin HM. Inhibition of IGF-IR tyrosine kinase induces apoptosis and cell cycle arrest in imatinib-resistant chronic myeloid leukaemia cells. J Cell Mol Med. 2010 Jun; 14(6B):1777-92. PMID: 19508387; PMCID: PMC3444523.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    77. Gelebart P, Zak Z, Anand M, Dien-Bard J, Amin HM, Lai R. Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism. Leukemia. 2009 Oct; 23(10):1836-46. PMID: 19494838.
      Citations: 17     Fields:    Translation:HumansCells
    78. Shi P, Lai R, Lin Q, Iqbal AS, Young LC, Kwak LW, Ford RJ, Amin HM. IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells. Blood. 2009 Jul 09; 114(2):360-70. PMID: 19423729; PMCID: PMC2714211.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    79. Bard JD, Gelebart P, Amin HM, Young LC, Ma Y, Lai R. Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4. FASEB J. 2009 May; 23(5):1405-14. PMID: 19151334.
      Citations: 23     Fields:    Translation:HumansCells
    80. Gelebart P, Anand M, Armanious H, Peters AC, Dien Bard J, Amin HM, Lai R. Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood. 2008 Dec 15; 112(13):5171-9. PMID: 18787224; PMCID: PMC2597612.
      Citations: 43     Fields:    Translation:HumansCells
    81. Bard JD, Gelebart P, Anand M, Amin HM, Lai R. Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma. Leukemia. 2008 Aug; 22(8):1595-603. PMID: 18509351; PMCID: PMC3429118.
      Citations: 42     Fields:    Translation:HumansCells
    82. Inamdar KV, Medeiros LJ, Jorgensen JL, Amin HM, Schlette EJ. Bone marrow involvement by marginal zone B-cell lymphomas of different types. Am J Clin Pathol. 2008 May; 129(5):714-22. PMID: 18426730.
      Citations: 3     Fields:    Translation:Humans
    83. Yu Z, Sun B, Kantarjian HM, Keating MJ, Amin HM, Sun X. Protein expression profiling of cytokines and cytokine receptors on purified chronic lymphocytic leukemia cells from patients with favourable prognostic indicators. Leuk Lymphoma. 2008 Apr; 49(4):751-6. PMID: 18398743.
      Citations: 2     Fields:    Translation:HumansCells
    84. Harb AJ, Amin HM, Verstovsek S, Quint?s-Cardama A. Granulocytic sarcoma with massive scalp involvement. Am J Hematol. 2008 Apr; 83(4):340-2. PMID: 17685484.
      Citations:    Fields:    Translation:Humans
    85. Ban K, Gao Y, Amin HM, Howard A, Miller C, Lin Q, Leng X, Munsell M, Bar-Eli M, Arlinghaus RB, Chandra J. BCR-ABL1 mediates up-regulation of Fyn in chronic myelogenous leukemia. Blood. 2008 Mar 01; 111(5):2904-8. PMID: 18180382; PMCID: PMC2254539.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    86. Amin HM, Hoshino K, Yang H, Lin Q, Lai R, Garcia-Manero G. Decreased expression level of SH2 domain-containing protein tyrosine phosphatase-1 (Shp1) is associated with progression of chronic myeloid leukaemia. J Pathol. 2007 Aug; 212(4):402-10. PMID: 17503411.
      Citations: 18     Fields:    Translation:HumansCells
    87. Yang J, Chai L, Liu F, Fink LM, Lin P, Silberstein LE, Amin HM, Ward DC, Ma Y. Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells. Proc Natl Acad Sci U S A. 2007 Jun 19; 104(25):10494-9. PMID: 17557835; PMCID: PMC1965541.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    88. Amin HM, Lai R. Pathobiology of ALK+ anaplastic large-cell lymphoma. Blood. 2007 Oct 01; 110(7):2259-67. PMID: 17519389; PMCID: PMC1988960.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    89. Ren Y, Medeiros LJ, Amin HM, Rytting ME, Jorgensen JL, Chen W. Unusual expression of CD94 on CD8+ TCR-alpha beta T cells in infectious mononucleosis. Ann Diagn Pathol. 2007 Feb; 11(1):55-60. PMID: 17240309.
      Citations:    Fields:    Translation:HumansCells
    90. Rosen DG, Mercado-Uribe I, Yang G, Bast RC, Amin HM, Lai R, Liu J. The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis. Cancer. 2006 Dec 01; 107(11):2730-40. PMID: 17063503.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    91. Cui W, Kong NR, Ma Y, Amin HM, Lai R, Chai L. Differential expression of the novel oncogene, SALL4, in lymphoma, plasma cell myeloma, and acute lymphoblastic leukemia. Mod Pathol. 2006 Dec; 19(12):1585-92. PMID: 16998462.
      Citations: 34     Fields:    Translation:HumansCells
    92. Lai R, Lefresne SV, Franko B, Hui D, Mirza I, Mansoor A, Amin HM, Ma Y. Immunoglobulin VH somatic hypermutation in mantle cell lymphoma: mutated genotype correlates with better clinical outcome. Mod Pathol. 2006 Nov; 19(11):1498-505. PMID: 16980950.
      Citations: 9     Fields:    Translation:HumansCells
    93. Shi X, Franko B, Frantz C, Amin HM, Lai R. JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells. Br J Haematol. 2006 Oct; 135(1):26-32. PMID: 16939498.
      Citations: 25     Fields:    Translation:HumansCells
    94. Hui D, Dabbagh L, Hanson J, Amin HM, Lai R. High ZAP-70 expression correlates with worse clinical outcome in mantle cell lymphoma. Leukemia. 2006 Oct; 20(10):1905-8. PMID: 16932342.
      Citations: 1     Fields:    Translation:Humans
    95. Dien J, Amin HM, Chiu N, Wong W, Frantz C, Chiu B, Mackey JR, Lai R. Signal transducers and activators of transcription-3 up-regulates tissue inhibitor of metalloproteinase-1 expression and decreases invasiveness of breast cancer. Am J Pathol. 2006 Aug; 169(2):633-42. PMID: 16877361; PMCID: PMC1698804.
      Citations: 19     Fields:    Translation:HumansCells
    96. Han Y, Amin HM, Frantz C, Franko B, Lee J, Lin Q, Lai R. Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma. Leukemia. 2006 Sep; 20(9):1602-9. PMID: 16871283.
      Citations: 30     Fields:    Translation:HumansCells
    97. Han Y, Amin HM, Franko B, Frantz C, Shi X, Lai R. Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma. Blood. 2006 Oct 15; 108(8):2796-803. PMID: 16825495.
      Citations: 83     Fields:    Translation:HumansCells
    98. Qiu L, Lai R, Lin Q, Lau E, Thomazy DM, Calame D, Ford RJ, Kwak LW, Kirken RA, Amin HM. Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells. Blood. 2006 Oct 01; 108(7):2407-15. PMID: 16763206; PMCID: PMC1895569.
      Citations: 43     Fields:    Translation:HumansAnimals
    99. Ma Y, Cui W, Yang J, Qu J, Di C, Amin HM, Lai R, Ritz J, Krause DS, Chai L. SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice. Blood. 2006 Oct 15; 108(8):2726-35. PMID: 16763212; PMCID: PMC1895586.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    100. Oyarzo MP, Drakos E, Atwell C, Amin HM, Medeiros LJ, Rassidakis GZ. Intrinsic apoptotic pathway in anaplastic large cell lymphoma. Hum Pathol. 2006 Jul; 37(7):874-82. PMID: 16784988.
      Citations: 2     Fields:    Translation:HumansCells
    101. Amin HM, Lin Q, Lai R. Jak3 contributes to the activation of ALK and Stat3 in ALK(+) anaplastic large cell lymphoma. Lab Invest. 2006 Apr; 86(4):417-9; author reply 420-1. PMID: 16554750.
      Citations: 3     Fields:    Translation:HumansCells
    102. Oyarzo MP, Medeiros LJ, Atwell C, Feretzaki M, Leventaki V, Drakos E, Amin HM, Rassidakis GZ. c-FLIP confers resistance to FAS-mediated apoptosis in anaplastic large-cell lymphoma. Blood. 2006 Mar 15; 107(6):2544-7. PMID: 16304056.
      Citations: 13     Fields:    Translation:HumansCells
    103. Lin Q, Lai R, Chirieac LR, Li C, Thomazy VA, Grammatikakis I, Rassidakis GZ, Zhang W, Fujio Y, Kunisada K, Hamilton SR, Amin HM. Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells. Am J Pathol. 2005 Oct; 167(4):969-80. PMID: 16192633; PMCID: PMC1603671.
      Citations: 90     Fields:    Translation:HumansCells
    104. Shishodia S, Amin HM, Lai R, Aggarwal BB. Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem Pharmacol. 2005 Sep 01; 70(5):700-13. PMID: 16023083.
      Citations: 130     Fields:    Translation:HumansCells
    105. Lai R, Rassidakis GZ, Lin Q, Atwell C, Medeiros LJ, Amin HM. Jak3 activation is significantly associated with ALK expression in anaplastic large cell lymphoma. Hum Pathol. 2005 Sep; 36(9):939-44. PMID: 16153455.
      Citations: 14     Fields:    Translation:HumansCells
    106. Amin HM, Yang Y, Shen Y, Estey EH, Giles FJ, Pierce SA, Kantarjian HM, O'Brien SM, Jilani I, Albitar M. Having a higher blast percentage in circulation than bone marrow: clinical implications in myelodysplastic syndrome and acute lymphoid and myeloid leukemias. Leukemia. 2005 Sep; 19(9):1567-72. PMID: 16049515.
      Citations: 9     Fields:    Translation:Humans
    107. Han XY, Lin P, Amin HM, Ferrajoli A. Postsplenectomy cytomegaloviral mononucleosis: marked lymphocytosis, TCRgamma gene rearrangements, and impaired IgM response. Am J Clin Pathol. 2005 Apr; 123(4):612-7. PMID: 15743745.
      Citations: 6     Fields:    Translation:HumansCells
    108. Sun X, Amin HM, Freireich EJ, Keating MJ, Kantarjian HM, Koller CA, O'Brien SM, Giles F, Albitar M. Hairy cell leukemia with large cells: long disease course with adequate response to therapy. Leukemia. 2004 Nov; 18(11):1912-4. PMID: 15385931.
      Citations:    Fields:    Translation:Humans
    109. Cho-Vega JH, Rassidakis GZ, Amin HM, Tsioli P, Spurgers K, Remache YK, Vega F, Goy AH, Gilles F, Medeiros LJ. Suppressor of cytokine signaling 3 expression in anaplastic large cell lymphoma. Leukemia. 2004 Nov; 18(11):1872-8. PMID: 15385932.
      Citations: 11     Fields:    Translation:HumansCells
    110. Rassidakis GZ, Feretzaki M, Atwell C, Grammatikakis I, Lin Q, Lai R, Claret FX, Medeiros LJ, Amin HM. Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma. Blood. 2005 Jan 15; 105(2):827-9. PMID: 15374880; PMCID: PMC1382060.
      Citations: 41     Fields:    Translation:HumansCells
    111. Khoury JD, Rassidakis GZ, Medeiros LJ, Amin HM, Lai R. Methylation of SHP1 gene and loss of SHP1 protein expression are frequent in systemic anaplastic large cell lymphoma. Blood. 2004 Sep 01; 104(5):1580-1. PMID: 15317731.
      Citations: 28     Fields:    Translation:HumansCells
    112. Cho-Vega JH, Rassidakis GZ, Admirand JH, Oyarzo M, Ramalingam P, Paraguya A, McDonnell TJ, Amin HM, Medeiros LJ. MCL-1 expression in B-cell non-Hodgkin's lymphomas. Hum Pathol. 2004 Sep; 35(9):1095-100. PMID: 15343511.
      Citations: 33     Fields:    Translation:HumansCells
    113. Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Oncogene. 2004 Jul 15; 23(32):5426-34. PMID: 15184887.
      Citations: 68     Fields:    Translation:HumansCells
    114. Lai R, Rassidakis GZ, Medeiros LJ, Ramdas L, Goy AH, Cutler C, Fujio Y, Kunisada K, Amin HM, Gilles F. Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Am J Pathol. 2004 Jun; 164(6):2251-8. PMID: 15161657; PMCID: PMC1615762.
      Citations: 4     Fields:    Translation:HumansCells
    115. Khoury JD, Medeiros LJ, Rassidakis GZ, Yared MA, Tsioli P, Leventaki V, Schmitt-Graeff A, Herling M, Amin HM, Lai R. Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell lymphoma. Clin Cancer Res. 2003 Sep 01; 9(10 Pt 1):3692-9. PMID: 14506160.
      Citations: 41     Fields:    Translation:HumansCells
    116. Amin HM, Medeiros LJ, Ma Y, Feretzaki M, Das P, Leventaki V, Rassidakis GZ, O'Connor SL, McDonnell TJ, Lai R. Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma. Oncogene. 2003 Aug 21; 22(35):5399-407. PMID: 12934099.
      Citations: 43     Fields:    Translation:HumansAnimals
    117. Amin HM, Jilani I, Estey EH, Keating MJ, Dey AL, Manshouri T, Kantarjian HM, Estrov Z, Cortes JE, Thomas DA, Giles FJ, Albitar M. Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome. Blood. 2003 Sep 01; 102(5):1866-8. PMID: 12730116.
      Citations: 8     Fields:    Translation:HumansCells
    118. Amin HM, McDonnell TJ, Medeiros LJ, Rassidakis GZ, Leventaki V, O'Connor SL, Keating MJ, Lai R. Characterization of 4 mantle cell lymphoma cell lines. Arch Pathol Lab Med. 2003 Apr; 127(4):424-31. PMID: 12683869.
      Citations: 58     Fields:    Translation:HumansCells
    119. Khoury JD, Amin HM, Jorgensen JL, Ostrowski ML, Bloom MG, Medeiros LJ. Composite thymoma and chronic lymphocytic leukemia/small lymphocytic lymphoma involving the anterior mediastinum. Arch Pathol Lab Med. 2003 Feb; 127(2):E76-9. PMID: 12562258.
      Citations: 4     Fields:    Translation:HumansCells
    120. Amin HM, Medeiros LJ, Manning JT, Jones D. Dissolution of the lymphoid follicle is a feature of the HHV8+ variant of plasma cell Castleman's disease. Am J Surg Pathol. 2003 Jan; 27(1):91-100. PMID: 12502931.
      Citations: 9     Fields:    Translation:HumansCells
    121. Nassr AKh, Hassan MM, Abdel Salam FM, Lashin AH, Shahin WA, Amin H. IgG isotypes in schistosomiasis patients before and after praziquantel. J Egypt Soc Parasitol. 2002 Dec; 32(3):931-52. PMID: 12512825.
      Citations: 1     Fields:    Translation:HumansAnimals
    122. Amin HM, McLaughlin P, Rutherford CJ, Abruzzo LV, Jones D. Cutaneous and systemic plasmacytosis in a patient of Asian descent living in the United States. Am J Dermatopathol. 2002 Jun; 24(3):241-5. PMID: 12140441.
      Citations: 6     Fields:    Translation:HumansCells
    123. Ni H, Ergin M, Huang Q, Qin JZ, Amin HM, Martinez RL, Saeed S, Barton K, Alkan S. Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis. Br J Haematol. 2001 Nov; 115(2):279-86. PMID: 11703322.
      Citations: 44     Fields:    Translation:HumansCells
    124. Amin HM, Saeed S, Alkan S. Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). Br J Haematol. 2001 Nov; 115(2):287-97. PMID: 11703323.
      Citations: 27     Fields:    Translation:HumansCells
    125. Amin HH, Petruzzelli GJ, Husain AN, Nickoloff BJ. Primary malignant melanoma of the larynx. Arch Pathol Lab Med. 2001 Feb; 125(2):271-3. PMID: 11175650.
      Citations: 6     Fields:    Translation:HumansCells
    126. Amin HM, Ergin M, Denning MF, Quevedo ME, Alkan S. Characterization of apoptosis induced by protein kinase C inhibitors and its modulation by the caspase pathway in acute promyelocytic leukaemia. Br J Haematol. 2000 Sep; 110(3):552-62. PMID: 10997964.
      Citations: 4     Fields:    Translation:HumansCells
    127. Amin HM, Ahmad S, Walenga JM, Hoppensteadt DA, Leitz H, Fareed J. Soluble P-selectin in human plasma: effect of anticoagulant matrix and its levels in patients with cardiovascular disorders. Clin Appl Thromb Hemost. 2000 Apr; 6(2):71-6. PMID: 10775025.
      Citations: 9     Fields:    Translation:Humans
    128. Amin HM, Candel AG, Husain AN. Pathologic quiz case. A 22-year-old man with an abdominal mass. Arch Pathol Lab Med. 1999 Jun; 123(6):541-3. PMID: 10383811.
      Citations: 1     Fields:    Translation:Humans
    129. Horn PC, Webster DA, Amin HM, Mascia MF, Werner FW, Fortino MD. The effect of hyperbaric oxygen on medial collateral ligament healing in a rat model. Clin Orthop Relat Res. 1999 Mar; (360):238-42. PMID: 10101330.
      Citations: 2     Fields:    Translation:Animals
    130. Amin HM, Zeller JA, Shen T, Nassar A. Sensitivity and specificity of the APC resistance assay in detection of individuals with factor V(Leiden) Am J Clin Pathol. 1997 Jun; 107(6):713-5. PMID: 9169671.
      Citations:    Fields:    Translation:Humans
    131. Ferrario L, Amin HM, Sugimori K, Camporesi EM, Hakim TS. Site of action of endogenous nitric oxide on pulmonary vasculature in rats. Pflugers Arch. 1996 Jul; 432(3):523-7. PMID: 8766013.
      Citations: 2     Fields:    Translation:Animals
    132. Sugimori K, Amin HM, Esposito BF, Seedat MS, Camporesi EM. Effect of slow versus fast desaturation on the ventilatory response to hypoxia. J Med. 1996; 27(5-6):277-92. PMID: 9151197.
      Citations: 1     Fields:    Translation:Humans
    133. Amin HM, Kaniewski WS, Cohen D, Camporesi EM, Hakim TS. Effects of acute exposure to hyperbaric oxygen on the rheology and morphology of the red blood cells in the rat. Microvasc Res. 1995 Nov; 50(3):417-28. PMID: 8583954.
      Citations:    Fields:    Translation:AnimalsCells
    134. Amin HM, Sopchak AM, Esposito BF, Henson LG, Batenhorst RL, Fox AW, Camporesi EM. Naloxone-induced and spontaneous reversal of depressed ventilatory responses to hypoxia during and after continuous infusion of remifentanil or alfentanil. J Pharmacol Exp Ther. 1995 Jul; 274(1):34-9. PMID: 7616418.
      Citations: 13     Fields:    Translation:Humans
    135. Amin HM, Hakim TS, Camporesi EM. Hematological alterations after acute exposure to hyperbaric oxygen in rats. Clin Exp Pharmacol Physiol. 1995 Jan; 22(1):21-7. PMID: 7768031.
      Citations: 1     Fields:    Translation:Animals
    136. Omran SA, Amin HM, el-Bassiouni NE, Essawy FM, Toiema SM. Vitamin K dependent coagulation proteins in endemic hepatosplenomegaly in Egypt. J Clin Pathol. 1994 Jun; 47(6):502-4. PMID: 8063929; PMCID: PMC494728.
      Citations: 3     Fields:    Translation:Humans
    137. Amin HM, Sopchak AM, Foss JF, Esposito BF, Roizen MF, Camporesi EM. Efficacy of methylnaltrexone versus naloxone for reversal of morphine-induced depression of hypoxic ventilatory response. Anesth Analg. 1994 Apr; 78(4):701-5. PMID: 8135389.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    138. Amin HM, Omran SA, el-Bassuoni NE, el-Kaliouby AH, el-Ashmawy SA. Assessment of factors II, VII, IX, X, and protein C in hepatosplenic schistosomiasis. Haemostasis. 1994 Jan-Feb; 24(1):22-6. PMID: 7959352.
      Citations: 1     Fields:    Translation:Humans
    139. Amin HM, Cigada M, Hakim TS, Camporesi EM. Pulmonary mechanical and vascular responses after acute hyperbaric oxygen exposure. Can J Physiol Pharmacol. 1993 Aug; 71(8):592-6. PMID: 8306197.
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