ASHA S MULTANI

TitleAssociate Professor
InstitutionMD Anderson
DepartmentGenetics
Address6767 Bertner St
Houston TX 77030-2603
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li M, Lulla AR, Wang Y, Tsavachidis S, Wang F, Karakas C, Nguyen TDT, Bui TN, Pina MA, Chen MK, Mastoraki S, Multani AS, Fowlkes NW, Sahin A, Marshall CG, Hunt KK, Keyomarsi K. Low Molecular Weight Cyclin E Confers a Vulnerability to PKMYT1 Inhibition in Triple-Negative Breast Cancer. Cancer Res. 2024 Aug 26. PMID: 39186665.
      Citations:    Fields:    
    2. Lee J, Kida K, Koh J, Liu H, Manyam GC, Gi YJ, Rampa DR, Multani AS, Wang J, Jayachandran G, Lee DW, Reuben JM, Sahin A, Huo L, Tripathy D, Im SA, Ueno NT. The DNA repair pathway as a therapeutic target to synergize with trastuzumab deruxtecan in HER2-targeted antibody-drug conjugate-resistant HER2-overexpressing breast cancer. J Exp Clin Cancer Res. 2024 Aug 21; 43(1):236. PMID: 39164784; PMCID: PMC11337831.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Zhao M, Wang T, Gleber-Netto FO, Chen Z, McGrail DJ, Gomez JA, Ju W, Gadhikar MA, Ma W, Shen L, Wang Q, Tang X, Pathak S, Raso MG, Burks JK, Lin SY, Wang J, Multani AS, Pickering CR, Chen J, Myers JN, Zhou G. Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response. Nat Commun. 2024 Jan 02; 15(1):180. PMID: 38167338; PMCID: PMC10761733.
      Citations: 6     Fields:    Translation:Humans
    4. Ghayee HK, Xu Y, Hatch H, Brockway R, Multani AS, Gu T, Bollag WB, Turcu A, Rainey WE, Rege J, Nanba K, Bhagwandin VJ, Nwariaku F, Stastny V, Gazdar AF, Shay JW, Auchus RJ, Tevosian SG. Development of Human Adrenocortical Adenoma (HAA1) Cell Line from Zona Reticularis. Int J Mol Sci. 2022 Dec 29; 24(1). PMID: 36614027; PMCID: PMC9820690.
      Citations:    Fields:    
    5. Li M, Tsavachidis S, Wang F, Bui T, Nguyen TDT, Luo L, Multani AS, Bondy ML, Hunt KK, Keyomarsi K. Low-molecular-weight cyclin E deregulates DNA replication and damage repair to promote genomic instability in breast cancer. Oncogene. 2022 Dec; 41(50):5331-5346. PMID: 36344674; PMCID: PMC9742291.
      Citations:    Fields:    Translation:HumansCells
    6. Song K, Minami JK, Huang A, Dehkordi SR, Lomeli SH, Luebeck J, Goodman MH, Moriceau G, Krijgsman O, Dharanipragada P, Ridgley T, Crosson WP, Salazar J, Pazol E, Karin G, Jayaraman R, Balanis NG, Alhani S, Sheu K, Ten Hoeve J, Palermo A, Motika SE, Senaratne TN, Paraiso KH, Hergenrother PJ, Rao PN, Multani AS, Peeper DS, Bafna V, Lo RS, Graeber TG. Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges. Cancer Discov. 2022 04 01; 12(4):1046-1069. PMID: 34930786; PMCID: PMC9192483.
      Citations: 2     Fields:    Translation:HumansCells
    7. Tigano A, Khan R, Omer AD, Weisz D, Dudchenko O, Multani AS, Pathak S, Behringer RR, Aiden EL, Fisher H, MacManes MD. Chromosome size affects sequence divergence between species through the interplay of recombination and selection. Evolution. 2022 04; 76(4):782-798. PMID: 35271737; PMCID: PMC9314927.
      Citations:    Fields:    Translation:AnimalsCells
    8. Zhang A, Thege FI, Cowan RW, Rupani DN, Wang R, Manning SL, Gates C, Wu W, Levin-Klein R, Rajapakshe KI, Yu M, Multani AS, Kang Y, Taniguchi CM, Schlacher K, Bellin MD, Katz MHG, Kim MP, Fleming JB, Gallinger S, Maddipati R, Harris RS, Notta F, Ross SR, Maitra A, Rhim AD, W?rmann SM. APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis. Nat Cancer. 2021 12; 2(12):1338-1356. PMID: 35121902.
      Citations:    Translation:HumansAnimals
    9. Bagheri-Yarmand R, Busaidy NL, McBeath E, Danysh BP, Evans KW, Moss TJ, Akcakanat A, Ng PKS, Knippler CM, Golden JA, Williams MD, Multani AS, Cabanillas ME, Shaw KR, Meric-Bernstam F, Shah MH, Ringel MD, Hofmann MC. RAC1 Alterations Induce Acquired Dabrafenib Resistance in Association with Anaplastic Transformation in a Papillary Thyroid Cancer Patient. Cancers (Basel). 2021 Sep 30; 13(19). PMID: 34638434; PMCID: PMC8507731.
      Citations: 1     
    10. Chakravarti D, Lee R, Multani AS, Santoni A, Keith Z, Hsu WH, Chang K, Reyes L, Rashid A, Wu CJ, Li J, Zhang J, Shim HS, Chandra K, Deng P, Spring DJ, Nielsen OH, Riis LB, Mayigegowda KK, Blutt SE, Zhang J, Younes M, DuPont A, Thirumurthi S, Vilar E, Estes MK, Colla S, Shroyer NF, DePinho RA. Telomere dysfunction instigates inflammation in inflammatory bowel disease. Proc Natl Acad Sci U S A. 2021 07 20; 118(29). PMID: 34253611; PMCID: PMC8307535.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    11. Hoencamp C, Dudchenko O, Elbatsh AMO, Brahmachari S, Raaijmakers JA, van Schaik T, van Heesbeen RGHP, van den Broek B, Mhaskar AN, Teunissen H, St Hilaire BG, Weisz D, Omer AD, Pham M, Colaric Z, Yang Z, Rao SSP, Mitra N, Lui C, Yao W, Khan R, Moroz LL, Kohn A, St Leger J, Mena A, Holcroft K, Gambetta MC, Lim F, Farley E, Stein N, Haddad A, Chauss D, Mutlu AS, Wang MC, Young ND, Hildebrandt E, Cheng HH, Knight CJ, Burnham TLU, Hovel KA, Beel AJ, Mattei PJ, Kornberg RD, Warren WC, Cary G, Hinman V, Lindblad-Toh K, Di Palma F, Maeshima K, Multani AS, Pathak S, Nel-Themaat L, Behringer RR, Kaur P, van Steensel B, de Wit E, Di Pierro M, Lieberman Aiden E, Rowland BD, Sede?o Cacciatore ?, Contessoto VG, G?mez-Skarmeta JL, Medema RH, Onuchic JN. 3D genomics across the tree of life reveals condensin II as a determinant of architecture type. Science. 2021 05 28; 372(6545):984-989. PMID: 34045355; PMCID: PMC8172041.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    12. Minussi DC, Nicholson MD, Ye H, Davis A, Wang K, Baker T, Tarabichi M, Sei E, Du H, Rabbani M, Peng C, Hu M, Bai S, Lin YW, Schalck A, Multani A, Ma J, McDonald TO, Casasent A, Barrera A, Chen H, Lim B, Arun B, Meric-Bernstam F, Van Loo P, Michor F, Navin NE. Breast tumours maintain a reservoir of subclonal diversity during expansion. Nature. 2021 04; 592(7853):302-308. PMID: 33762732; PMCID: PMC8049101.
      Citations: 24     Fields:    Translation:HumansCells
    13. Chen B, Dragomir MP, Fabris L, Bayraktar R, Liu X, Tang C, Li Y, Shimura T, Ivkovic TC, De Los Santos MC, Anfossi S, Shimizu M, Shah MY, Ling H, Shen P, Multani AS, Pardini B, Burks JK, Katayama H, Reineke LC, Huo L, Syed M, Song S, Ferracin M, Oki E, Fromm B, Ivan C, Bhuvaneshwar K, Gusev Y, Mimori K, Menter D, Sen S, Matsuyama T, Uetake H, Vasilescu C, Kopetz S, Parker-Thornburg J, Taguchi A, Hanash SM, Girnita L, Slaby O, Goel A, Varani G, Gagea M, Li C, Ajani JA, Calin GA, Knutsen E. The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling. Gastroenterology. 2020 12; 159(6):2146-2162.e33. PMID: 32805281; PMCID: PMC7725986.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    14. Msaouel P, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, Shapiro DD, Perelli L, Srinivasan S, Carbone F, Karki M, Seervai RNH, Lopez-Terrada D, Cheng EH, Tang X, Lu W, Wistuba II, Thompson TC, Giuliani V, Schlacher K, Carugo A, Heffernan TP, Sharma P, Karam JA, Wood CG, Walker CL, Genovese G, Tannir NM, Malouf GG, Pili? PG, Vokshi BH, Davidson I. Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer Cell. 2020 05 11; 37(5):720-734.e13. PMID: 32359397; PMCID: PMC7288373.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    15. Wu S, Gao F, Zheng S, Zhang C, Martinez-Ledesma E, Ezhilarasan R, Ding J, Li X, Feng N, Multani A, Sulman EP, Verhaak RG, de Groot JF, Heffernan TP, Yung WKA, Koul D. EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma. Clin Cancer Res. 2020 03 15; 26(6):1395-1407. PMID: 31852834.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    16. Wang R, Chu GC, Wang X, Wu JB, Hu P, Multani AS, Pathak S, Zhau HE, Chung LWK. Establishment and characterization of a prostate cancer cell line from a prostatectomy specimen for the study of cellular interaction. Int J Cancer. 2019 10 15; 145(8):2249-2259. PMID: 31020641; PMCID: PMC6703920.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    17. Veletic I, Manshouri T, Multani AS, Yin CC, Chen L, Verstovsek S, Estrov Z. Myelofibrosis osteoclasts are clonal and functionally impaired. Blood. 2019 05 23; 133(21):2320-2324. PMID: 30745304; PMCID: PMC6533604.
      Citations: 5     Fields:    Translation:HumansCells
    18. Long DJ, Gaikwad A, Multani A, Pathak S, Montgomery CA, Gonzalez FJ, Jaiswal AK. Retraction: Disruption of the NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Gene in Mice Causes Myelogenous Hyperplasia. Cancer Res. 2018 Nov 15; 78(22):6526. PMID: 30442815.
      Citations:    Fields:    
    19. Achuthan V, Perreira JM, Sowd GA, Puray-Chavez M, McDougall WM, Paulucci-Holthauzen A, Wu X, Fadel HJ, Poeschla EM, Multani AS, Hughes SH, Sarafianos SG, Brass AL, Engelman AN. Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. Cell Host Microbe. 2018 09 12; 24(3):392-404.e8. PMID: 30173955; PMCID: PMC6368089.
      Citations: 80     Fields:    Translation:HumansCells
    20. Wang M, Liang L, Lei X, Multani A, Meric-Bernstam F, Tripathy D, Wu Y, Chen H, Zhang H. Evaluation of cMET aberration by immunohistochemistry and fluorescence in situ hybridization (FISH) in triple negative breast cancers. Ann Diagn Pathol. 2018 Aug; 35:69-76. PMID: 29843069.
      Citations: 3     Fields:    Translation:Humans
    21. deCarvalho AC, Kim H, Poisson LM, Winn ME, Mueller C, Cherba D, Koeman J, Seth S, Protopopov A, Felicella M, Zheng S, Multani A, Jiang Y, Zhang J, Nam DH, Petricoin EF, Chin L, Mikkelsen T, Verhaak RGW. Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma. Nat Genet. 2018 05; 50(5):708-717. PMID: 29686388; PMCID: PMC5934307.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    22. Shah MY, Ferracin M, Pileczki V, Chen B, Redis R, Fabris L, Zhang X, Ivan C, Shimizu M, Rodriguez-Aguayo C, Dragomir M, Van Roosbroeck K, Almeida MI, Ciccone M, Nedelcu D, Cortez MA, Manshouri T, Calin S, Muftuoglu M, Banerjee PP, Badiwi MH, Parker-Thornburg J, Multani A, Welsh JW, Estecio MR, Ling H, Tomuleasa C, Dima D, Yang H, Alvarez H, You MJ, Radovich M, Shpall E, Fabbri M, Rezvani K, Girnita L, Berindan-Neagoe I, Maitra A, Verstovsek S, Fodde R, Bueso-Ramos C, Gagea M, Manero GG, Calin GA. Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations. Genome Res. 2018 04; 28(4):432-447. PMID: 29567676; PMCID: PMC5880235.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    23. Ong DST, Hu B, Ho YW, Bristow CA, Wang Q, Multani AS, Chen P, Nezi L, Jiang S, Gorman CE, Monasterio MM, Koul D, Marchesini M, Colla S, Jin EJ, Sulman EP, Spring DJ, Yung WA, Verhaak RGW, Chin L, Wang YA, DePinho RA, Sauv? CG. PAF promotes stemness and radioresistance of glioma stem cells. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):E9086-E9095. PMID: 29073105; PMCID: PMC5664518.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    24. Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, Palaskas N, Wu H, Multani AS, Port E, Larson SM, Braas D, Christofk HR, Mellinghoff IK, Graeber TG, M?schen M, Schultz N. Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. Mol Syst Biol. 2017 02 15; 13(2):914. PMID: 28202506; PMCID: PMC5327725.
      Citations: 34     Fields:    Translation:HumansCells
    25. Rai R, Multani AS, Chang S. Cytogenetic Analysis of Telomere Dysfunction. Methods Mol Biol. 2017; 1587:127-131. PMID: 28324504.
      Citations: 1     Fields:    Translation:AnimalsCells
    26. Niu N, Zhang J, Zhang N, Mercado-Uribe I, Tao F, Han Z, Pathak S, Multani AS, Kuang J, Yao J, Bast RC, Sood AK, Hung MC, Liu J. Linking genomic reorganization to tumor initiation via the giant cell cycle. Oncogenesis. 2016 Dec 19; 5(12):e281. PMID: 27991913; PMCID: PMC5177773.
      Citations: 52     
    27. Sneige N, Hess KR, Multani AS, Gong Y, Ibrahim NK. Prognostic significance of equivocal human epidermal growth factor receptor 2 results and clinical utility of alternative chromosome 17 genes in patients with invasive breast cancer: A cohort study. Cancer. 2017 04 01; 123(7):1115-1123. PMID: 27893937; PMCID: PMC5372352.
      Citations: 11     Fields:    Translation:HumansCells
    28. Sun Y, Ji P, Chen T, Zhou X, Yang D, Guo Y, Liu Y, Hu L, Xia D, Liu Y, Multani AS, Shmulevich I, Kucherlapati R, Kopetz S, Sood AK, Hamilton SR, Sun B, Zhang W. MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer. J Pathol. 2017 Jan; 241(1):67-79. PMID: 27741356; PMCID: PMC5315452.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    29. Verstovsek S, Manshouri T, Pilling D, Bueso-Ramos CE, Newberry KJ, Prijic S, Knez L, Bozinovic K, Harris DM, Spaeth EL, Post SM, Multani AS, Rampal RK, Ahn J, Levine RL, Creighton CJ, Kantarjian HM, Estrov Z. Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis. J Exp Med. 2016 08 22; 213(9):1723-40. PMID: 27481130; PMCID: PMC4995084.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    30. McAuliffe PF, Evans KW, Akcakanat A, Chen K, Zheng X, Zhao H, Eterovic AK, Sangai T, Holder AM, Sharma C, Chen H, Do KA, Tarco E, Gagea M, Naff KA, Sahin A, Multani AS, Black DM, Mittendorf EA, Bedrosian I, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F. Correction: Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes. PLoS One. 2016; 11(3):e0151121. PMID: 26953790; PMCID: PMC4782992.
      Citations: 2     Fields:    
    31. Gallardo M, Lee HJ, Zhang X, Bueso-Ramos C, Pageon LR, McArthur M, Multani A, Nazha A, Manshouri T, Parker-Thornburg J, Rapado I, Quintas-Cardama A, Kornblau SM, Martinez-Lopez J, Post SM. hnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies. Cancer Cell. 2015 Oct 12; 28(4):486-499. PMID: 26412324; PMCID: PMC4652598.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    32. McAuliffe PF, Evans KW, Akcakanat A, Chen K, Zheng X, Zhao H, Eterovic AK, Sangai T, Holder AM, Sharma C, Chen H, Do KA, Tarco E, Gagea M, Naff KA, Sahin A, Multani AS, Black DM, Mittendorf EA, Bedrosian I, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F. Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes. PLoS One. 2015; 10(9):e0136851. PMID: 26325287; PMCID: PMC4556673.
      Citations: 32     Fields:    Translation:HumansAnimals
    33. Colla S, Ong DS, Ogoti Y, Marchesini M, Mistry NA, Clise-Dwyer K, Ang SA, Storti P, Viale A, Giuliani N, Ruisaard K, Ganan Gomez I, Bristow CA, Estecio M, Weksberg DC, Ho YW, Hu B, Genovese G, Pettazzoni P, Multani AS, Jiang S, Hua S, Ryan MC, Carugo A, Nezi L, Wei Y, Yang H, D'Anca M, Zhang L, Gaddis S, Gong T, Horner JW, Heffernan TP, Jones P, Cooper LJ, Liang H, Kantarjian H, Wang YA, Chin L, Bueso-Ramos C, Garcia-Manero G, DePinho RA. Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome. Cancer Cell. 2015 May 11; 27(5):644-57. PMID: 25965571; PMCID: PMC4596059.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    34. Riley MF, You MJ, Multani AS, Lozano G. Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma. Oncogene. 2016 Jan 21; 35(3):358-65. PMID: 25915849; PMCID: PMC4624041.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    35. Wang Y, Waters J, Leung ML, Unruh A, Roh W, Shi X, Chen K, Scheet P, Vattathil S, Liang H, Multani A, Zhang H, Zhao R, Michor F, Meric-Bernstam F, Navin NE. Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature. 2014 Aug 14; 512(7513):155-60. PMID: 25079324; PMCID: PMC4158312.
      Citations: 443     Fields:    Translation:HumansCells
    36. Wagner KW, Alam H, Dhar SS, Giri U, Li N, Wei Y, Giri D, Cascone T, Kim JH, Ye Y, Multani AS, Chan CH, Erez B, Saigal B, Chung J, Lin HK, Wu X, Hung MC, Heymach JV, Lee MG. KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling. J Clin Invest. 2013 Dec; 123(12):5231-46. PMID: 24200691; PMCID: PMC3859406.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    37. Malouf GG, Monzon FA, Escudier B, Su X, Yao H, Tamboli P, Lopez-Terrada D, Picken M, Garcia M, Multani AS, Pathak S, Wood CG, Tannir NM, Couturier J, Molini? V, Camparo P. Genomic heterogeneity of translocation renal cell carcinoma. Clin Cancer Res. 2013 Sep 01; 19(17):4673-84. PMID: 23817689; PMCID: PMC3882157.
      Citations: 29     Fields:    Translation:HumansCells
    38. Ling H, Spizzo R, Atlasi Y, Nicoloso M, Shimizu M, Redis RS, Nishida N, Song J, Guo Z, Ivan C, Barbarotto E, De Vries I, Zhang X, Ferracin M, Churchman M, van Galen JF, Beverloo BH, Shariati M, Haderk F, Estecio MR, Garcia-Manero G, Patijn GA, Gotley DC, Bhardwaj V, Shureiqi I, Sen S, Multani AS, Welsh J, Yamamoto K, Taniguchi I, Song MA, Gallinger S, Casey G, Thibodeau SN, Tiirikainen M, Mani SA, Zhang W, Davuluri RV, Mimori K, Mori M, Sieuwerts AM, Martens JW, Tomlinson I, Negrini M, Berindan-Neagoe I, Foekens JA, Hamilton SR, Lanza G, Kopetz S, Fodde R, Calin GA, Gaf? R, Le Marchand L. CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res. 2013 Sep; 23(9):1446-61. PMID: 23796952; PMCID: PMC3759721.
      Citations: 314     Fields:    Translation:HumansAnimalsCells
    39. Chen X, Liu B, Li Q, Honorio S, Liu X, Liu C, Multani AS, Calhoun-Davis T, Tang DG. Dissociated primary human prostate cancer cells coinjected with the immortalized Hs5 bone marrow stromal cells generate undifferentiated tumors in NOD/SCID-? mice. PLoS One. 2013; 8(2):e56903. PMID: 23451107; PMCID: PMC3579939.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    40. Yang G, Mercado-Uribe I, Multani AS, Sen S, Shih IeM, Wong KK, Gershenson DM, Liu J. RAS promotes tumorigenesis through genomic instability induced by imbalanced expression of Aurora-A and BRCA2 in midbody during cytokinesis. Int J Cancer. 2013 Jul 15; 133(2):275-85. PMID: 23319376; PMCID: PMC3883442.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    41. Maiti SN, Huls H, Singh H, Dawson M, Figliola M, Olivares S, Rao P, Zhao YJ, Multani A, Yang G, Zhang L, Crossland D, Ang S, Torikai H, Rabinovich B, Lee DA, Kebriaei P, Hackett P, Champlin RE, Cooper LJ. Sleeping beauty system to redirect T-cell specificity for human applications. J Immunother. 2013 Feb; 36(2):112-23. PMID: 23377665; PMCID: PMC3568214.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    42. Singh MM, Howard A, Irwin ME, Gao Y, Lu X, Multani A, Chandra J. Expression and activity of Fyn mediate proliferation and blastic features of chronic myelogenous leukemia. PLoS One. 2012; 7(12):e51611. PMID: 23284724; PMCID: PMC3524192.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    43. Ramirez E, Singh RR, Kunkalla K, Liu Y, Qu C, Cain C, Multani AS, Lennon PA, Jackacky J, Ho M, Dawud S, Gu J, Yang S, Hu PC, Vega F. Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma. Leuk Res. 2012 Oct; 36(10):1267-73. PMID: 22809693; PMCID: PMC3422406.
      Citations: 2     Fields:    Translation:HumansCells
    44. Akbay EA, Peña CG, Ruder D, Michel JA, Nakada Y, Pathak S, Multani AS, Chang S, Castrillon DH, Akbay EA, Pe?a CG. Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis. Oncogene. 2013 Apr 25; 32(17):2211-9. PMID: 22689059; PMCID: PMC3636499.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    45. Nanos-Webb A, Jabbour NA, Multani AS, Wingate H, Oumata N, Meijer L, Hunt KK, Keyomarsi K, Galons H, Joseph B. Targeting low molecular weight cyclin E (LMW-E) in breast cancer. Breast Cancer Res Treat. 2012 Apr; 132(2):575-88. PMID: 21695458; PMCID: PMC3855283.
      Citations: 22     Fields:    Translation:HumansCells
    46. Deriano L, Chaumeil J, Coussens M, Multani A, Chou Y, Alekseyenko AV, Chang S, Skok JA, Roth DB. The RAG2 C terminus suppresses genomic instability and lymphomagenesis. Nature. 2011 Mar 03; 471(7336):119-23. PMID: 21368836; PMCID: PMC3174233.
      Citations: 57     Fields:    Translation:AnimalsCells
    47. Multani AS, Chang S. Cytogenetic analysis of telomere dysfunction. Methods Mol Biol. 2011; 735:139-43. PMID: 21461818; PMCID: PMC3725757.
      Citations: 3     Fields:    Translation:AnimalsCells
    48. Rai R, Zheng H, He H, Luo Y, Multani A, Carpenter PB, Chang S. The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J. 2010 Aug 04; 29(15):2598-610. PMID: 20588252; PMCID: PMC2928694.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    49. Yang G, Chang B, Yang F, Guo X, Cai KQ, Xiao XS, Wang H, Sen S, Hung MC, Mills GB, Chang S, Multani AS, Mercado-Uribe I, Liu J. Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. Clin Cancer Res. 2010 Jun 15; 16(12):3171-81. PMID: 20423983; PMCID: PMC2930838.
      Citations: 63     Fields:    Translation:HumansCells
    50. Liang Y, Gao H, Lin SY, Peng G, Huang X, Zhang P, Goss JA, Brunicardi FC, Multani AS, Chang S, Li K. BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice. PLoS Genet. 2010 Jan 22; 6(1):e1000826. PMID: 20107607; PMCID: PMC2809772.
      Citations: 57     Fields:    Translation:AnimalsCells
    51. Thalmann GN, Rhee H, Sikes RA, Pathak S, Multani A, Zhau HE, Marshall FF, Chung LW. Human prostate fibroblasts induce growth and confer castration resistance and metastatic potential in LNCaP Cells. Eur Urol. 2010 Jul; 58(1):162-71. PMID: 19747763; PMCID: PMC2889152.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    52. Atanassov BS, Evrard YA, Multani AS, Zhang Z, Devys D, Chang S, Dent SY, Tora L. Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance. Mol Cell. 2009 Aug 14; 35(3):352-64. PMID: 19683498; PMCID: PMC2749492.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    53. Vega F, Davuluri Y, Cho-Vega JH, Singh RR, Ma S, Wang RY, Multani AS, Drakos E, Pham LV, Lee YC, Shen L, Ambrus J, Medeiros LJ, Ford RJ. Side population of a murine mantle cell lymphoma model contains tumour-initiating cells responsible for lymphoma maintenance and dissemination. J Cell Mol Med. 2010 Jun; 14(6B):1532-45. PMID: 19656242; PMCID: PMC3829019.
      Citations: 9     Fields:    Translation:AnimalsCells
    54. Jaiswal AS, Aneja R, Connors SK, Joshi HC, Multani AS, Pathak S, Narayan S. 9-bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells. J Cell Biochem. 2009 Apr 15; 106(6):1146-56. PMID: 19229861; PMCID: PMC2728348.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    55. Sung SY, Hsieh CL, Law A, Zhau HE, Pathak S, Multani AS, Lim S, Coleman IM, Wu LC, Figg WD, Dahut WL, Nelson P, Lee JK, Amin MB, Lyles R, Johnstone PA, Marshall FF, Chung LW. Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res. 2008 Dec 01; 68(23):9996-10003. PMID: 19047182; PMCID: PMC3105756.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    56. He H, Wang Y, Guo X, Ramchandani S, Ma J, Shen MF, Garcia DA, Deng Y, Multani AS, You MJ, Chang S. Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita. Mol Cell Biol. 2009 Jan; 29(1):229-40. PMID: 18936156; PMCID: PMC2612488.
      Citations: 55     Fields:    Translation:AnimalsCells
    57. Li ZG, Mathew P, Yang J, Starbuck MW, Zurita AJ, Liu J, Sikes C, Multani AS, Efstathiou E, Lopez A, Wang J, Fanning TV, Prieto VG, Kundra V, Vazquez ES, Troncoso P, Raymond AK, Logothetis CJ, Lin SH, Maity S, Navone NM. Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. J Clin Invest. 2008 Aug; 118(8):2697-710. PMID: 18618013; PMCID: PMC2447924.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    58. Bhatia B, Jiang M, Suraneni M, Patrawala L, Badeaux M, Schneider-Broussard R, Multani AS, Jeter CR, Calhoun-Davis T, Hu L, Hu J, Tsavachidis S, Zhang W, Chang S, Hayward SW, Tang DG. Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. J Biol Chem. 2008 Oct 10; 283(41):27957-27972. PMID: 18662989; PMCID: PMC2562067.
      Citations: 21     Fields:    Translation:HumansCells
    59. Bhatia B, Multani AS, Patrawala L, Chen X, Calhoun-Davis T, Zhou J, Schroeder L, Schneider-Broussard R, Shen J, Pathak S, Chang S, Tang DG. Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT. Int J Cancer. 2008 Apr 01; 122(7):1483-95. PMID: 18059027.
      Citations: 22     Fields:    Translation:HumansCells
    60. Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M. Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature. 2008 Mar 20; 452(7185):365-9. PMID: 18354482; PMCID: PMC2707768.
      Citations: 120     Fields:    Translation:HumansCells
    61. Singh B, Cook KR, Vincent L, Hall CS, Berry JA, Multani AS, Lucci A. Cyclooxygenase-2 induces genomic instability, BCL2 expression, doxorubicin resistance, and altered cancer-initiating cell phenotype in MCF7 breast cancer cells. J Surg Res. 2008 Jun 15; 147(2):240-6. PMID: 18498876.
      Citations: 28     Fields:    Translation:HumansCells
    62. Akli S, Van Pelt CS, Bui T, Multani AS, Chang S, Johnson D, Tucker S, Keyomarsi K. Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway. Cancer Res. 2007 Aug 01; 67(15):7212-22. PMID: 17671189.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    63. Singh B, Vincent L, Berry JA, Multani AS, Lucci A. Cyclooxygenase-2 expression induces genomic instability in MCF10A breast epithelial cells. J Surg Res. 2007 Jun 15; 140(2):220-6. PMID: 17418864.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    64. Cosme-Blanco W, Shen MF, Lazar AJ, Pathak S, Lozano G, Multani AS, Chang S. Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence. EMBO Rep. 2007 May; 8(5):497-503. PMID: 17396137; PMCID: PMC1866197.
      Citations: 83     Fields:    Translation:AnimalsCells
    65. Multani AS, Chang S. WRN at telomeres: implications for aging and cancer. J Cell Sci. 2007 Mar 01; 120(Pt 5):713-21. PMID: 17314245.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    66. Ford RJ, Shen L, Lin-Lee YC, Pham LV, Multani A, Zhou HJ, Tamayo AT, Zhang C, Hawthorn L, Cowell JK, Ambrus JL. Development of a murine model for blastoid variant mantle-cell lymphoma. Blood. 2007 Jun 01; 109(11):4899-906. PMID: 17311992; PMCID: PMC1885517.
      Citations: 11     Fields:    Translation:AnimalsCells
    67. Xu J, Wang R, Xie ZH, Odero-Marah V, Pathak S, Multani A, Chung LW, Zhau HE. Prostate cancer metastasis: role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis. Prostate. 2006 Nov 01; 66(15):1664-73. PMID: 16902972.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    68. He H, Multani AS, Cosme-Blanco W, Tahara H, Ma J, Pathak S, Deng Y, Chang S. POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination. EMBO J. 2006 Nov 01; 25(21):5180-90. PMID: 17053789; PMCID: PMC1630418.
      Citations: 60     Fields:    Translation:AnimalsCells
    69. Qutob SS, Multani AS, Pathak S, McNamee JP, Bellier PV, Liu QY, Ng CE. Fractionated X-radiation treatment can elicit an inducible-like radioprotective response that is not dependent on the intrinsic cellular X-radiation resistance/sensitivity. Radiat Res. 2006 Oct; 166(4):590-9. PMID: 17007548.
      Citations: 5     Fields:    Translation:HumansCells
    70. Kupferman ME, Patel V, Sriuranpong V, Amornphimoltham P, Jasser SA, Mandal M, Zhou G, Wang J, Coombes K, Multani A, Pathak S, Silvio Gutkind J, Myers JN. Molecular analysis of anoikis resistance in oral cavity squamous cell carcinoma. Oral Oncol. 2007 May; 43(5):440-54. PMID: 16978912.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    71. Rai R, Dai H, Multani AS, Li K, Chin K, Gray J, Lahad JP, Liang J, Mills GB, Meric-Bernstam F, Lin SY. BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer. Cancer Cell. 2006 Aug; 10(2):145-57. PMID: 16872911; PMCID: PMC1557410.
      Citations: 79     Fields:    Translation:HumansCells
    72. Wu L, Multani AS, He H, Cosme-Blanco W, Deng Y, Deng JM, Bachilo O, Pathak S, Tahara H, Bailey SM, Deng Y, Behringer RR, Chang S. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell. 2006 Jul 14; 126(1):49-62. PMID: 16839876.
      Citations: 218     Fields:    Translation:AnimalsCells
    73. Pathak S, Multani AS. Aneuploidy, stem cells and cancer. EXS. 2006; (96):49-64. PMID: 16383014.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    74. Laud PR, Multani AS, Bailey SM, Wu L, Ma J, Kingsley C, Lebel M, Pathak S, DePinho RA, Chang S. Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway. Genes Dev. 2005 Nov 01; 19(21):2560-70. PMID: 16264192; PMCID: PMC1276730.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    75. Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, Hruban RH, Rustgi AK, Chang S, Tuveson DA. Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell. 2005 May; 7(5):469-83. PMID: 15894267.
      Citations: 1142     Fields:    Translation:AnimalsCells
    76. Chen JS, Konopleva M, Andreeff M, Multani AS, Pathak S, Mehta K. Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis. J Cell Physiol. 2004 Aug; 200(2):223-34. PMID: 15174092.
      Citations: 11     Fields:    Translation:HumansCells
    77. Chang S, Multani AS, Cabrera NG, Naylor ML, Laud P, Lombard D, Pathak S, Guarente L, DePinho RA. Essential role of limiting telomeres in the pathogenesis of Werner syndrome. Nat Genet. 2004 Aug; 36(8):877-82. PMID: 15235603.
      Citations: 188     Fields:    Translation:AnimalsCells
    78. Akli S, Zheng PJ, Multani AS, Wingate HF, Pathak S, Zhang N, Tucker SL, Chang S, Keyomarsi K. Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer. Cancer Res. 2004 May 01; 64(9):3198-208. PMID: 15126360.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    79. Pathak S, Multani AS, Narayan S, Furlong CL, Hsu TC. Germline Telomere Length Dynamics and Mutagen Sensitivity Studies in a Family with Acute Reactions to Sun Exposure: Involvement of Three Generations. Cancer Genomics Proteomics. 2004 May-Jun; 1(3):199-208. PMID: 31394654.
      Citations:    Fields:    
    80. Qutob SS, Multani AS, Pathak S, Feng Y, Kendal WS, Ng CE. Comparison of the X-radiation, drug and ultraviolet-radiation responses of clones isolated from a human colorectal tumor cell line. Radiat Res. 2004 Mar; 161(3):326-34. PMID: 14982481.
      Citations:    Fields:    Translation:HumansCells
    81. Jaiswal AS, Multani AS, Pathak S, Narayan S. N-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA. Mol Cancer. 2004 Jan 16; 3:3. PMID: 14728717; PMCID: PMC320492.
      Citations: 8     Fields:    Translation:HumansCells
    82. Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, El-Naggar AK, Multani A, Chang S, Lozano G. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nat Genet. 2004 Jan; 36(1):63-8. PMID: 14702042.
      Citations: 142     Fields:    Translation:Animals
    83. Pathak S, Multani AS, Banerji P, Banerji P. Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer. Int J Oncol. 2003 Oct; 23(4):975-82. PMID: 12963976.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    84. Strickland FM, Pathak S, Multani AS, Pelley RP, Donawho CK. Molecular characterization of new melanoma cell lines from C3H mice induced by ethanol plus ultraviolet radiation. Cancer Res. 2003 Jul 01; 63(13):3503-10. PMID: 12839934.
      Citations: 3     Fields:    Translation:AnimalsCells
    85. Chinni SR, Alhasan SA, Multani AS, Pathak S, Sarkar FH. Pleotropic effects of genistein on MCF-7 breast cancer cells. Int J Mol Med. 2003 Jul; 12(1):29-34. PMID: 12792805.
      Citations: 6     Fields:    Translation:HumansCells
    86. Zhang X, Multani AS, Zhou JH, Shay JW, McConkey D, Dong L, Kim CS, Rosser CJ, Pathak S, Benedict WF. Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells. Cancer Res. 2003 Feb 15; 63(4):760-5. PMID: 12591722.
      Citations: 13     Fields:    Translation:HumansCells
    87. Mehta K, Devarajan E, Chen J, Multani A, Pathak S. Multidrug-resistant MCF-7 cells: an identity crisis? J Natl Cancer Inst. 2002 Nov 06; 94(21):1652-4; author reply 1654. PMID: 12419794.
      Citations: 16     Fields:    Translation:HumansCells
    88. Sohn SH, Multani AS, Gugnani PK, Pathak S. Telomere erosion-induced mitotic catastrophe in continuously grown chinese hamster don cells. Exp Cell Res. 2002 Oct 01; 279(2):271-6. PMID: 12243752.
      Citations: 1     Fields:    Translation:AnimalsCells
    89. Weber KL, Pathak S, Multani AS, Price JE. Characterization of a renal cell carcinoma cell line derived from a human bone metastasis and establishment of an experimental nude mouse model. J Urol. 2002 Aug; 168(2):774-9. PMID: 12131367.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    90. Long DJ, Gaikwad A, Multani A, Pathak S, Montgomery CA, Gonzalez FJ, Jaiswal AK. Disruption of the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene in mice causes myelogenous hyperplasia. Cancer Res. 2002 Jun 01; 62(11):3030-6. PMID: 12036909.
      Citations: 36     Fields:    Translation:AnimalsCells
    91. Devarajan E, Chen J, Multani AS, Pathak S, Sahin AA, Mehta K. Human breast cancer MCF-7 cell line contains inherently drug-resistant subclones with distinct genotypic and phenotypic features. Int J Oncol. 2002 May; 20(5):913-20. PMID: 11956583.
      Citations: 14     Fields:    Translation:HumansCells
    92. Pathak S, Multani AS, Furlong CL, Sohn SH. Telomere dynamics, aneuploidy, stem cells, and cancer (review). Int J Oncol. 2002 Mar; 20(3):637-41. PMID: 11836581.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    93. Shou J, Ali-Osman F, Multani AS, Pathak S, Fedi P, Srivenugopal KS. Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA. Oncogene. 2002 Jan 31; 21(6):878-89. PMID: 11840333.
      Citations: 67     Fields:    Translation:HumansCells
    94. Multani AS, Worth LL, Jeha S, Chan KW, Pathak S. Human bone marrow transplant rejection is associated with telomere cleavage. Int J Mol Med. 2001 Dec; 8(6):607-10. PMID: 11712073.
      Citations:    Fields:    Translation:HumansCells
    95. Fishman P, Bar-Yehuda S, Barer F, Madi L, Multani AS, Pathak S. The A3 adenosine receptor as a new target for cancer therapy and chemoprotection. Exp Cell Res. 2001 Oct 01; 269(2):230-6. PMID: 11570815.
      Citations: 42     Fields:    Translation:AnimalsCells
    96. Narayan S, Jaiswal AS, Multani AS, Pathak S. DNA damage-induced cell cycle checkpoints involve both p53-dependent and -independent pathways: role of telomere repeat binding factor 2. Br J Cancer. 2001 Sep 14; 85(6):898-901. PMID: 11556843; PMCID: PMC2375064.
      Citations: 3     Fields:    Translation:HumansCells
    97. Multani AS, Ozen M, Furlong CL, Zhao YJ, Hsu TC, Pathak S. Heterochromatin and interstitial telomeric DNA homology. Chromosoma. 2001 Jul; 110(3):214-20. PMID: 11513296.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    98. Rhee HW, Zhau HE, Pathak S, Multani AS, Pennanen S, Visakorpi T, Chung LW. Permanent phenotypic and genotypic changes of prostate cancer cells cultured in a three-dimensional rotating-wall vessel. In Vitro Cell Dev Biol Anim. 2001 Mar; 37(3):127-40. PMID: 11370803.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    99. Pathak S, Multani AS, McConkey DJ, Imam AS, Amoss MS. Spontaneous regression of cutaneous melanoma in sinclair swine is associated with defective telomerase activity and extensive telomere erosion. Int J Oncol. 2000 Dec; 17(6):1219-24. PMID: 11078808.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    100. Fishman P, Bar-Yehuda S, Ohana G, Pathak S, Wasserman L, Barer F, Multani AS. Adenosine acts as an inhibitor of lymphoma cell growth: a major role for the A3 adenosine receptor. Eur J Cancer. 2000 Jul; 36(11):1452-8. PMID: 10899660.
      Citations: 31     Fields:    Translation:AnimalsCells
    101. Pathak S, Multani AS, Narayan S, Kumar V, Newman RA. Anvirzel, an extract of Nerium oleander, induces cell death in human but not murine cancer cells. Anticancer Drugs. 2000 Jul; 11(6):455-63. PMID: 11001386.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    102. Multani AS, Ozen M, Narayan S, Kumar V, Chandra J, McConkey DJ, Newman RA, Pathak S. Caspase-dependent apoptosis induced by telomere cleavage and TRF2 loss. Neoplasia. 2000 Jul-Aug; 2(4):339-45. PMID: 11005568; PMCID: PMC1550291.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    103. Multani AS, Ozen M, Sen S, Mandal AK, Price JE, Fan D, Radinsky R, Ali-Osman F, Von Eschenbach AC, Fidler IJ, Pathak S. Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin. Int J Oncol. 1999 Sep; 15(3):423-9. PMID: 10427120.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    104. Pratesi G, Tortoreto M. Human tumor xenografts in nude mice are not always of human origin. A warning signal. Cancer. 1999 Sep 01; 86(5):898-900. PMID: 10463991.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    105. Multani AS, Pathak S. Conventional cytogenetics alone is not sufficient for identifying interspecies cell line contamination. Anticancer Res. 1999 May-Jun; 19(3A):1753-4. PMID: 10470110.
      Citations:    Fields:    Translation:HumansAnimalsCells
    106. Multani AS, Ozen M, Agrawal A, Hopwood VL, von Eschenbach AC, Pathak S. Amplification of the Y chromosome in three murine tumor cell lines transformed in vivo by different human prostate cancers. In Vitro Cell Dev Biol Anim. 1999 Apr; 35(4):236-9. PMID: 10478804.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    107. Pai SA, Cheung MC, Romsdahl MM, Multani AS, Pathak S. Can genetic instability be studied at the single chromosome level in cancer cells? Evidence from human melanoma cells. Cancer Genet Cytogenet. 1999 Feb; 109(1):51-7. PMID: 9973960.
      Citations:    Fields:    Translation:HumansCells
    108. Multani AS, Chandra J, Mcconker J, Sen S, Cabral TF, Pathak S. Cell death in paclitaxel-dependent chinese hamster ovary cells is initiated by the loss of telomeric DNA repeats. Oncol Res. 1999; 11(10):455-60. PMID: 10850886.
      Citations: 1     Fields:    Translation:AnimalsCells
    109. Multani AS, Li C, Ozen M, Imam AS, Wallace S, Pathak S. Cell-killing by paclitaxel in a metastatic murine melanoma cell line is mediated by extensive telomere erosion with no decrease in telomerase activity. Oncol Rep. 1999 Jan-Feb; 6(1):39-44. PMID: 9864398.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    110. Pathak S, Nemeth MA, Multani AS. Human tumor xenografts in nude mice are not always of human origin: a warning signal. Cancer. 1998 Nov 01; 83(9):1891-3. PMID: 9806646.
      Citations: 7     Fields:    Translation:HumansAnimals
    111. Multani AS, Furlong C, Pathak S. Reduction of telomeric signals in murine melanoma and human breast cancer cell lines treated with 3'-azido-2'-3'-dideoxythymidine. Int J Oncol. 1998 Nov; 13(5):923-5. PMID: 9772280.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    112. Ozen M, Navone NM, Multani AS, Troncoso P, Logothetis CJ, Chung LW, von Eschenbach AC, Pathak S. Structural alterations of chromosome 5 in twelve human prostate cancer cell lines. Cancer Genet Cytogenet. 1998 Oct 15; 106(2):105-9. PMID: 9797773.
      Citations: 1     Fields:    Translation:HumansCells
    113. Ozen M, Imam SA, Datar RH, Multani AS, Narayanan R, Chung LW, von Eschenbach AC, Pathak S. Telomeric DNA: marker for human prostate cancer development? Prostate. 1998 Sep 01; 36(4):264-71. PMID: 9719027.
      Citations: 1     Fields:    Translation:HumansCells
    114. Mukhopadhyay T, Multani AS, Roth JA, Pathak S. Reduced telomeric signals and increased telomeric associations in human lung cancer cell lines undergoing p53-mediated apoptosis. Oncogene. 1998 Aug 20; 17(7):901-6. PMID: 9780006.
      Citations: 1     Fields:    Translation:HumansCells
    115. Büssing A, Multani AS, Pathak S, Pfüller U, Schietzel M, B?ssing A, Pf?ller U. Induction of apoptosis by the N-acetyl-galactosamine-specific toxic lectin from Viscum album L. is associated with a decrease of nuclear p53 and Bcl-2 proteins and induction of telomeric associations. Cancer Lett. 1998 Aug 14; 130(1-2):57-68. PMID: 9751257.
      Citations: 7     Fields:    Translation:HumansCells
    116. Pathak S, Multani AS, Ozen M, Richardson MA, Newman RA. Dolastatin-10 induces polyploidy, telomeric associations and apoptosis in a murine melanoma cell line. Oncol Rep. 1998 Mar-Apr; 5(2):373-6. PMID: 9468560.
      Citations: 8     Fields:    Translation:AnimalsCells
    117. Pathak S, Dolhonde JA, Multani AS. Amplification of telomeric DNA and the extent of karyotypic evolution. Cytobios. 1998; 93(374):141-6. PMID: 9779588.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    118. Multani AS, Li C, Ozen M, Yadav M, Yu DF, Wallace S, Pathak S. Paclitaxel and water-soluble poly (L-glutamic acid)-paclitaxel, induce direct chromosomal abnormalities and cell death in a murine metastatic melanoma cell line. Anticancer Res. 1997 Nov-Dec; 17(6D):4269-74. PMID: 9494519.
      Citations: 4     Fields:    Translation:AnimalsCells
    119. Augenlicht LH, Wadler S, Corner G, Richards C, Ryan L, Multani AS, Pathak S, Benson A, Haller D, Heerdt BG. Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: a frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial. Cancer Res. 1997 May 01; 57(9):1769-75. PMID: 9135021.
      Citations: 45     Fields:    Translation:HumansCTClinical Trials
    120. Multani AS, Kacker RK, Pathak S. Are Robertsonian translocations rare in cancers? Cancer Genet Cytogenet. 1997 Feb; 93(2):179-80. PMID: 9078306.
      Citations: 1     Fields:    Translation:HumansAnimals
    121. Ozen M, Multani AS, Kuniyasu H, Chung LW, von Eschenbach AC, Pathak S. Specific histologic and cytogenetic evidence for in vivo malignant transformation of murine host cells by three human prostate cancer cell lines. Oncol Res. 1997; 9(8):433-8. PMID: 9436196.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    122. Pathak S, Nemeth MA, Multani AS, Thalmann GN, von Eschenbach AC, Chung LW. Can cancer cells transform normal host cells into malignant cells? Br J Cancer. 1997; 76(9):1134-8. PMID: 9365160; PMCID: PMC2228111.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    123. Multani AS, Hopwood VL, Pathak S. A modified fluorescence in situ hybridization (FISH) technique. Anticancer Res. 1996 Nov-Dec; 16(6B):3435-7. PMID: 9042203.
      Citations: 3     Fields:    Translation:AnimalsCells
    124. Multani AS, Sheth FJ, Shah VC, Chinoy NJ, Pathak S. Three siblings with Harlequin Ichthyosis in an Indian family. Early Hum Dev. 1996 Jul 19; 45(3):229-33. PMID: 8855396.
      Citations: 1     Fields:    Translation:Humans
    125. Yadav M, Hopwood VL, Multani AS, Mansfield PF, Takahashi Y, McIntyre BW, Udagawa T, Pathak S. Non-random primary and secondary chromosomal abnormalities in human gastric cancers. Anticancer Res. 1996 Jul-Aug; 16(4A):1787-95. PMID: 8712702.
      Citations: 1     Fields:    Translation:HumansCells
    126. Ozen M, Multani A, Chang S, Voneschenbach A, Chung L, Pathak S. Establishment of an in vitro cell model system to study human prostate carcinogenesis. Int J Oncol. 1996 May; 8(5):883-8. PMID: 21544441.
      Citations: 2     Fields:    
    127. Sheth FJ, Multani AS, Sheth JJ, Radhakrishna U, Shah VC, Chinoy NJ. Incomplete gonadal dysgenesis. Urol Int. 1996; 56(1):57-60. PMID: 8903559.
      Citations: 1     Fields:    Translation:Humans
    128. Prognostic significance of equivocal human epidermal growth factor receptor 2 results and clinical utility of alternative chromosome 17 genes in patients with invasive breast cancer. Cancer.
    129. MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer. Journal of Pathology. 241:67-79.
    130. Fragility in the 14q21q translocation region. Genetics and Molecular Biology. 25:271-276.
    131. Maternal inheritance of a 10/15 translocation in a female with a history of obstetric problems. Brazilian Journal of Genetics. 19:497-500.
    132. Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma. Oncogene.
    133. Ability to generate patient-derived Breast cancer xenografts is enhanced in chemoresistant disease and predicts poor patient outcomes. PLoS One. 10.
    134. Germline telomere length dynamics and mutagen sensitivity studies in a family with acute reactions to sun exposure. Cancer Genomics and Proteomics. 1:199-208.
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