ADEL K EL-NAGGAR

TitleProfessor
InstitutionMD Anderson
DepartmentPathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hoff CO, Dal Lago EA, Siqueira JM, de Sousa LG, El-Naggar AK, Ahnert JR, Ferrarotto R. First Use of AXL Targeting in Metastatic, Refractory, Adenoid Cystic Carcinoma: A Case Report. JCO Precis Oncol. 2024 Apr; 8:e2300633. PMID: 38579194.
      Citations:    Fields:    
    2. Dal Lago EA, Sousa LG, Yang Z, Hoff CO, Bonini F, Sawyer M, Wang K, Lewis W, Wahid KA, Hanna EY, El-Naggar A, Fuller CD, Kundu S, Godoy M, Ferrarotto R. Prognostic value of tumor volume doubling time in lung-metastatic adenoid cystic carcinoma. Oral Oncol. 2024 Apr; 151:106759. PMID: 38507991.
      Citations:    Fields:    
    3. Klijanienko J, Masliah-Planchon J, Choussy O, Rougier G, Vautrin AD, Lesnik M, Badois N, Ghanem W, Klos J, Tourneau CL, Marret G, Barnhill R, El-Naggar AK. Is Primary Poorly Differentiated Sarcomatoid Malignancy of the Parotid Gland Sarcomatoid Undifferentiated/Dedifferentiated Melanoma ? Report of three unusual cases diagnosed by fine needle aspiration combined with histological, immunohistochemical and molecular analyses. Acta Cytol. 2024 Mar 04. PMID: 38437817.
      Citations:    Fields:    
    4. Dibra D, Xiong S, Moyer SM, El-Naggar AK, Qi Y, Su X, Kong EK, Korkut A, Lozano G. Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo. Sci Adv. 2024 Feb 16; 10(7):eadk1835. PMID: 38354236; PMCID: PMC10866549.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Wong SJ, Torres-Saavedra PA, Saba NF, Shenouda G, Bumpous JM, Wallace RE, Chung CH, El-Naggar AK, Gwede CK, Burtness B, Tennant PA, Dunlap NE, Redman R, Stokes WA, Rudra S, Mell LK, Sacco AG, Spencer SA, Nabell L, Yao M, Cury FL, Mitchell DL, Jones CU, Firat S, Contessa JN, Galloway T, Currey A, Harris J, Curran WJ, Le QT. Radiotherapy Plus Cisplatin With or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial. JAMA Oncol. 2023 Nov 01; 9(11):1565-1573. PMID: 37768670; PMCID: PMC10540060.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    6. Siqueira JM, Mitani Y, Hoff CO, Bonini F, Guimaraes de Sousa L, Marques-Piubelli ML, Purushothaman A, Mitani M, Dai H, Lin SY, Spiotto MT, Hanna EY, McGrail DJ, El-Naggar AK, Ferrarotto R. Analysis of B7-H4 Expression Across Salivary Gland Carcinomas Reveals Adenoid Cystic Carcinoma-Specific Prognostic Relevance. Mod Pathol. 2024 Jan; 37(1):100371. PMID: 38015043.
      Citations: 1     Fields:    Translation:Humans
    7. Sousa LG, McGrail DJ, Lazar Neto F, Li K, Marques-Piubelli ML, Ferri-Borgogno S, Dai H, Mitani Y, Spardy Burr N, Cooper ZA, Kinneer K, Cortez MA, Lin SY, Bell D, El Naggar A, Burks J, Ferrarotto R. Spatial Immunoprofiling of Adenoid Cystic Carcinoma Reveals B7-H4 Is a Therapeutic Target for Aggressive Tumors. Clin Cancer Res. 2023 08 15; 29(16):3162-3171. PMID: 37256648; PMCID: PMC10526680.
      Citations:    Fields:    Translation:Humans
    8. Dibra D, Moyer SM, El-Naggar AK, Qi Y, Su X, Lozano G. Triple-negative breast tumors are dependent on mutant p53 for growth and survival. Proc Natl Acad Sci U S A. 2023 08 22; 120(34):e2308807120. PMID: 37579145; PMCID: PMC10450424.
      Citations: 5     Fields:    Translation:HumansAnimals
    9. Persson M, Andersson MK, Sahlin PE, Mitani Y, Brandwein-Weber MS, Frierson HF, Moskaluk C, Fonseca I, Ferrarotto R, Boecker W, Loening T, El-Naggar AK, Stenman G. Comprehensive molecular characterization of adenoid cystic carcinoma reveals tumor suppressors as novel drivers and prognostic biomarkers. J Pathol. 2023 11; 261(3):256-268. PMID: 37565350.
      Citations: 2     Fields:    Translation:HumansCells
    10. Ferrarotto R, Mitani Y, McGrail DJ, Li K, Karpinets TV, Bell D, Frank SJ, Song X, Kupferman ME, Liu B, Lee JJ, Glisson BS, Zhang J, Aster JC, Lin SY, Futreal PA, Heymach JV, El-Naggar AK. Correction: Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets. Clin Cancer Res. 2023 Jul 14; 29(14):2737. PMID: 37449360.
      Citations:    Fields:    
    11. Wotman M, El-Naggar A, Ferrarotto R. Targeting human EGFR 2 (HER2) in salivary gland carcinoma. Expert Rev Anticancer Ther. 2023 06; 23(6):573-582. PMID: 37114470.
      Citations:    Fields:    Translation:Humans
    12. Ferrarotto R, Sousa LG, Feng L, Mott F, Blumenschein G, Altan M, Bell D, Bonini F, Li K, Marques-Piubelli ML, Dal Lago EA, Johnson JJ, Mitani Y, Godoy M, Lee A, Kupferman M, Hanna E, Glisson BS, Elamin Y, El-Naggar A. Phase II Clinical Trial of Axitinib and Avelumab in Patients With Recurrent/Metastatic Adenoid Cystic Carcinoma. J Clin Oncol. 2023 05 20; 41(15):2843-2851. PMID: 36898078; PMCID: PMC10414730.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    13. Brayer KJ, Kang H, El-Naggar AK, Andreasen S, Hom?e P, Kiss K, Mikkelsen L, Heegaard S, Pelaez D, Moeyersoms A, Tse DT, Guo Y, Lee DY, Ness SA. Dominant Gene Expression Profiles Define Adenoid Cystic Carcinoma (ACC) from Different Tissues: Validation of a Gene Signature Classifier for Poor Survival in Salivary Gland ACC. Cancers (Basel). 2023 Feb 22; 15(5). PMID: 36900183; PMCID: PMC10000625.
      Citations: 3     
    14. William WN, Zhang J, Zhao X, Parra ER, Uraoka N, Lin HY, Peng SA, El-Naggar AK, Rodriguez-Canales J, Song J, Gillenwater AM, Wistuba II, Myers JN, Gold KA, Ferrarotto R, Hwu P, Davoli T, Lee JJ, Heymach JV, Papadimitrakopoulou VA, Lippman SM. Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort. Cancer. 2023 03 01; 129(5):714-727. PMID: 36597662; PMCID: PMC10508302.
      Citations:    Fields:    Translation:HumansCells
    15. Caudell JJ, Torres-Saavedra PA, Rosenthal DI, Axelrod RS, Nguyen-Tan PF, Sherman EJ, Weber RS, Galvin JM, El-Naggar AK, Konski AA, Echevarria MI, Dunlap NE, Shenouda G, Singh AK, Beitler JJ, Garsa A, Bonner JA, Garden AS, Algan O, Harris J, Le QT. Long-Term Update of NRG/RTOG 0522: A Randomized Phase 3 Trial of Concurrent Radiation and Cisplatin With or Without Cetuximab in Locoregionally Advanced Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2023 07 01; 116(3):533-543. PMID: 36549347; PMCID: PMC10247515.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    16. Johnson FM, Janku F, Gouda MA, Tran HT, Kawedia JD, Schmitz D, Streefkerk H, Lee JJ, Andersen CR, Deng D, Rawal S, Shah PA, El-Naggar AK, Johnson JM, Frederick MJ. Inhibition of the Phosphatidylinositol-3 Kinase Pathway Using Bimiralisib in Loss-of-Function NOTCH1-Mutant Head and Neck Cancer. Oncologist. 2022 12 09; 27(12):1004-e926. PMID: 36124629; PMCID: PMC9732253.
      Citations:    
    17. Persson M, Andersson MK, Mitani Y, Brandwein-Weber MS, Frierson HF, Moskaluk C, Fonseca I, Ferrarotto R, Boecker W, Loening T, El-Naggar AK, Stenman G. Rearrangements, Expression, and Clinical Significance of MYB and MYBL1 in Adenoid Cystic Carcinoma: A Multi-Institutional Study. Cancers (Basel). 2022 Jul 28; 14(15). PMID: 35954356; PMCID: PMC9367430.
      Citations:    
    18. Xiong S, Chachad D, Zhang Y, Gencel-Augusto J, Sirito M, Pant V, Yang P, Sun C, Chau G, Qi Y, Su X, Whitley EM, El-Naggar AK, Lozano G. Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo. Cancer Res. 2022 05 16; 82(10):1926-1936. PMID: 35320355; PMCID: PMC9117479.
      Citations:    Fields:    Translation:AnimalsCells
    19. Ferrarotto R, Amit M, Nagarajan P, Rubin ML, Yuan Y, Bell D, El-Naggar AK, Johnson JM, Morrison WH, Rosenthal DI, Glisson BS, Johnson FM, Lu C, Mott FE, Esmaeli B, Diaz EM, Gidley PW, Goepfert RP, Lewis CM, Weber RS, Wargo JA, Basu S, Duan F, Yadav SS, Sharma P, Allison JP, Myers JN, Gross ND. Correction: Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res. 2022 Apr 14; 28(8):1735. PMID: 35419587.
      Citations:    Fields:    
    20. Symer DE, Akagi K, Geiger HM, Song Y, Li G, Emde AK, Xiao W, Jiang B, Toussaint NC, Li J, Agrawal A, Ozer E, El-Naggar AK, Du Z, Shewale JB, Stache-Crain B, Zucker M, Robine N, Coombes KR, Gillison ML, Corvelo A. Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers. Genome Res. 2022 01; 32(1):55-70. PMID: 34903527; PMCID: PMC8744672.
      Citations:    Fields:    Translation:HumansCells
    21. Sousa LG, Wang K, Torman D, Binks BJ, Rubin ML, Andersen CR, Lewis WE, Rivera MJ, Kaya D, El-Naggar AK, Hanna EY, Esmaeli B, Frank SJ, Bell D, Glisson BS, Rodon J, Meric-Bernstam F, Lee JJ, Ferrarotto R. Treatment patterns and outcomes of palliative systemic therapy in patients with salivary duct carcinoma and adenocarcinoma, not otherwise specified. Cancer. 2022 02 01; 128(3):509-518. PMID: 34661906.
      Citations:    Fields:    Translation:Humans
    22. Amit M, Liu C, Mansour J, Gleber-Netto FO, Tam S, Baruch EN, Aashiq M, El-Naggar AK, Moreno AC, Rosenthal DI, Glisson BS, Ferrarotto R, Wong MK, Tsai K, Flores ER, Migden MR, Silverman DA, Li G, Khanna A, Goepfert RP, Nagarajan P, Weber RS, Myers JN, Gross ND. Elective neck dissection versus observation in patients with head and neck cutaneous squamous cell carcinoma. Cancer. 2021 12 01; 127(23):4413-4420. PMID: 34358340; PMCID: PMC10187975.
      Citations:    Fields:    Translation:Humans
    23. Ferrarotto R, Amit M, Nagarajan P, Rubin ML, Yuan Y, Bell D, El-Naggar AK, Johnson JM, Morrison WH, Rosenthal DI, Glisson BS, Johnson FM, Lu C, Mott FE, Esmaeli B, Diaz EM, Gidley PW, Goepfert RP, Lewis CM, Weber RS, Wargo JA, Basu S, Duan F, Yadav SS, Sharma P, Allison JP, Myers JN, Gross ND. Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res. 2021 08 15; 27(16):4557-4565. PMID: 34187851; PMCID: PMC8711237.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    24. Gunn GB, Garden AS, Ye R, Ausat N, Dahlstrom KR, Morrison WH, Fuller CD, Phan J, Reddy JP, Shah SJ, Mayo LL, Chun SG, Chronowski GM, Moreno AC, Myers JN, Hanna EY, Esmaeli B, Gillison ML, Ferrarotto R, Hutcheson KA, Chambers MS, Ginsberg LE, El-Naggar AK, Rosenthal DI, Zhu XR, Frank SJ. Proton Therapy for Head and Neck Cancer: A 12-Year, Single-Institution Experience. Int J Part Ther. 2021; 8(1):108-118. PMID: 34285940; PMCID: PMC8270083.
      Citations:    
    25. Sherry AD, Pasalic D, Gunn GB, Fuller CD, Phan J, Rosenthal DI, Morrison WH, Sturgis EM, Gross ND, Gillison ML, Ferrarotto R, El-Naggar AK, Garden AS, Frank SJ. Proton Beam Therapy for Head and Neck Carcinoma of Unknown Primary: Toxicity and Quality of Life. Int J Part Ther. 2021; 8(1):234-247. PMID: 34285950; PMCID: PMC8270080.
      Citations:    
    26. Karpinets TV, Mitani Y, Liu B, Zhang J, Pytynia KB, Sellen LD, Karagiannis DT, Ferrarotto R, Futreal AP, El-Naggar AK. Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations. Clin Cancer Res. 2021 07 15; 27(14):3960-3969. PMID: 34011559; PMCID: PMC8598082.
      Citations: 3     Fields:    Translation:Humans
    27. Lulla AR, Akli S, Karakas C, Ha MJ, Fowlkes NW, Mitani Y, Bui T, Wang J, Rao X, Hunt KK, Meijer L, El-Naggar AK, Keyomarsi K. LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers. Oncogenesis. 2021 May 14; 10(5):40. PMID: 33990543; PMCID: PMC8121779.
      Citations:    
    28. Mandal M, Kim S, Younes MN, Jasser SA, El-Naggar AK, Mills GB, Myers JN. Retraction Note to: The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells. Br J Cancer. 2021 May; 124(10):1747. PMID: 33603199; PMCID: PMC8110797.
      Citations:    Fields:    
    29. Wang J, Hu Y, Escamilla-Rivera V, Gonzalez CL, Tang L, Wang B, El-Naggar AK, Myers JN, Caulin C. Epithelial Mutant p53 Promotes Resistance to Anti-PD-1-Mediated Oral Cancer Immunoprevention in Carcinogen-Induced Mouse Models. Cancers (Basel). 2021 Mar 23; 13(6). PMID: 33806894; PMCID: PMC8005156.
      Citations: 1     
    30. Tam S, Gajera M, Luo X, Glisson BS, Ferrarotto R, Johnson FM, Mott FE, Gillison ML, Lu C, Le X, Blumenschein GR, Wong MK, Rosenthal DI, Nagarajan P, El-Naggar AK, Midgen MR, Weber RS, Myers JN, Gross ND. Cytotoxic and targeted systemic therapy in patients with advanced cutaneous squamous cell carcinoma in the head and neck. Head Neck. 2021 05; 43(5):1592-1603. PMID: 33522021.
      Citations: 1     Fields:    Translation:Humans
    31. Huang C, Chen L, Savage SR, Eguez RV, Dou Y, Li Y, da Veiga Leprevost F, Jaehnig EJ, Lei JT, Wen B, Schnaubelt M, Krug K, Song X, Cieslik M, Chang HY, Wyczalkowski MA, Li K, Colaprico A, Li QK, Clark DJ, Hu Y, Cao L, Pan J, Wang Y, Cho KC, Shi Z, Liao Y, Jiang W, Anurag M, Ji J, Yoo S, Zhou DC, Liang WW, Wendl M, Vats P, Carr SA, Mani DR, Zhang Z, Qian J, Chen XS, Pico AR, Wang P, Chinnaiyan AM, Ketchum KA, Kinsinger CR, Robles AI, An E, Hiltke T, Mesri M, Thiagarajan M, Weaver AM, Sikora AG, Lubinski J, Wierzbicka M, Wiznerowicz M, Satpathy S, Gillette MA, Miles G, Ellis MJ, Omenn GS, Rodriguez H, Boja ES, Dhanasekaran SM, Ding L, Nesvizhskii AI, El-Naggar AK, Chan DW, Zhang H, Zhang B, Clinical Proteomic Tumor Analysis Consortium. Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma. Cancer Cell. 2021 03 08; 39(3):361-379.e16. PMID: 33417831; PMCID: PMC7946781.
      Citations: 42     Fields:    Translation:Humans
    32. Amit M, Liu C, Netto Gleber FO, Kini S, Tam S, Benov A, Aashiq M, El-Naggar AK, Moreno AC, Rosenthal DI, Glisson BS, Ferrarotto R, Wong MK, Migden MR, Li G, Khanna A, Goepfert RP, Nagarajan P, Weber RS, Myers JN, Gross ND. Integrating depth of invasion in T classification improves the prognostic performance of the American Joint Committee on Cancer primary tumor staging system for cutaneous squamous cell carcinoma of the head and neck. Eur J Cancer. 2021 02; 144:169-177. PMID: 33352413.
      Citations:    Fields:    Translation:Humans
    33. Amit M, Liu C, Gleber-Netto FO, Kini S, Tam S, Benov A, Aashiq M, El-Naggar AK, Moreno AC, Rosenthal DI, Glisson BS, Ferrarotto R, Wong MK, Migden MR, Baruch EN, Li G, Khanna A, Goepfert RP, Nagarajan P, Weber RS, Myers JN, Gross ND. Inclusion of extranodal extension in the lymph node classification of cutaneous squamous cell carcinoma of the head and neck. Cancer. 2021 04 15; 127(8):1238-1245. PMID: 33320343.
      Citations: 2     Fields:    Translation:Humans
    34. Ferrarotto R, Mitani Y, McGrail DJ, Li K, Karpinets TV, Bell D, Frank SJ, Song X, Kupferman ME, Liu B, Lee JJ, Glisson BS, Zhang J, Aster JC, Lin SY, Futreal PA, Heymach JV, El-Naggar AK. Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets. Clin Cancer Res. 2021 02 01; 27(3):852-864. PMID: 33172898; PMCID: PMC7854509.
      Citations: 6     Fields:    Translation:HumansCells
    35. Choi KY, Amit M, Tam S, Bell D, Phan J, Garden AS, Williams MD, Ferrarotto R, El-Naggar AK, Raza SM, DeMonte F, Kupferman ME, Hanna EY, Su SY. Clinical Implication of Diagnostic and Histopathologic Discrepancies in Sinonasal Malignancies. Laryngoscope. 2021 05; 131(5):E1468-E1475. PMID: 32946597.
      Citations: 1     Fields:    Translation:Humans
    36. Hofman P, El-Naggar AK, Vielh P, Balogh Z, Suciu V, Richon C, Job B, Meurice G, Valent A, Lacroix L, Marty V, Motte N, Dessen P, Caillou B, Ghuzlan AA, Bidart JM, Lazar V, Scoazec JY, Schlumberger M. DNA FISH Diagnostic Assay on Cytological Samples of Thyroid Follicular Neoplasms. Cancers (Basel). 2020 Sep 06; 12(9). PMID: 32899953; PMCID: PMC7564487.
      Citations:    
    37. Lee DY, Brayer KJ, Mitani Y, Burns EA, Rao PH, Bell D, Williams MD, Ferrarotto R, Pytynia KB, El-Naggar AK, Ness SA. Oncogenic Orphan Nuclear Receptor NR4A3 Interacts and Cooperates with MYB in Acinic Cell Carcinoma. Cancers (Basel). 2020 Aug 27; 12(9). PMID: 32867110; PMCID: PMC7565926.
      Citations: 1     
    38. Williams MD, El-Naggar AK. Pathology and Differential Diagnosis of Anterior Skull Base Tumours. Adv Otorhinolaryngol. 2020; 84:13-27. PMID: 32731232.
      Citations:    Fields:    Translation:Humans
    39. Tomoum MO, Askar MH, Hamad AH, El-Naggar A, Amer M. Third window approach assisted middle meatal antrostomy: prospective cohort study of the two ports technique in management of hard to reach maxillary sinus pathology. J Laryngol Otol. 2020 Jul; 134(7):636-641. PMID: 32686629.
      Citations: 1     Fields:    Translation:Humans
    40. Ford JR, Rubin ML, Frank SJ, Ning J, Debnam JM, Bell D, El-Naggar A, Ferrarotto R, Esmaeli B. Prognostic factors for local recurrence and survival and impact of local treatments on survival in lacrimal gland carcinoma. Br J Ophthalmol. 2021 06; 105(6):768-774. PMID: 32680839.
      Citations: 1     Fields:    Translation:Humans
    41. Amit M, Takahashi H, Dragomir MP, Lindemann A, Gleber-Netto FO, Pickering CR, Anfossi S, Osman AA, Cai Y, Wang R, Knutsen E, Shimizu M, Ivan C, Rao X, Wang J, Silverman DA, Tam S, Zhao M, Caulin C, Zinger A, Tasciotti E, Dougherty PM, El-Naggar A, Calin GA, Myers JN. Loss of p53 drives neuron reprogramming in head and neck cancer. Nature. 2020 02; 578(7795):449-454. PMID: 32051587; PMCID: PMC9723538.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    42. Tam S, Yao CMKL, Amit M, Gajera M, Luo X, Treistman R, Khanna A, Aashiq M, Nagarajan P, Bell D, El-Naggar A, Migden M, Wong M, Glisson B, Ferrarotto R, Esmaeli B, Rosenthal D, Li G, Weber RS, Myers JN, Gross ND. Association of Immunosuppression With Outcomes of Patients With Cutaneous Squamous Cell Carcinoma of the Head and Neck. JAMA Otolaryngol Head Neck Surg. 2020 02 01; 146(2):128-135. PMID: 31804658; PMCID: PMC6902183.
      Citations: 5     Fields:    Translation:Humans
    43. Frerich CA, Sedam HN, Kang H, Mitani Y, El-Naggar AK, Ness SA. N-Terminal Truncated Myb with New Transcriptional Activity Produced Through Use of an Alternative MYB Promoter in Salivary Gland Adenoid Cystic Carcinoma. Cancers (Basel). 2019 Dec 21; 12(1). PMID: 31877778; PMCID: PMC7016764.
      Citations: 2     
    44. Mitani Y, Lin SH, Pytynia KB, Ferrarotto R, El-Naggar AK. Reciprocal and Autonomous Glucocorticoid and Androgen Receptor Activation in Salivary Duct Carcinoma. Clin Cancer Res. 2020 03 01; 26(5):1175-1184. PMID: 31772120; PMCID: PMC7056500.
      Citations: 4     Fields:    Translation:HumansCells
    45. Bell D, Ferrarotto R, Liang L, Goepfert RP, Li J, Ning J, Broaddus R, Weber RS, El-Naggar AK. Pan-Trk immunohistochemistry reliably identifies ETV6-NTRK3 fusion in secretory carcinoma of the salivary gland. Virchows Arch. 2020 Feb; 476(2):295-305. PMID: 31423558.
      Citations: 7     Fields:    Translation:Humans
    46. Oh SH, Kim WY, Kim JH, Younes MN, El-Naggar AK, Myers JN, Kies M, Cohen P, Khuri F, Hong WK, Lee HY. Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2019 08 01; 25(15):4861. PMID: 31371311.
      Citations:    Fields:    
    47. Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN, Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN. Editor's Note: Epidermal Growth Factor Receptor (EGFR) Is Overexpressed in Anaplastic Thyroid Cancer, and the EGFR Inhibitor Gefitinib Inhibits the Growth of Anaplastic Thyroid Cancer. Clin Cancer Res. 2019 08 01; 25(15):4862. PMID: 31371312.
      Citations: 1     Fields:    
    48. Saluja K, Ravishankar S, Ferrarotto R, Zhu H, Pytynia KB, El-Naggar AK. Ectopic ACTH Production and Cushing's Syndrome in a Patient with Parotid Acinic Cell Carcinoma with High-Grade Transformation: Tumor Context and Clinical Implications. Head Neck Pathol. 2020 Jun; 14(2):562-569. PMID: 31363907; PMCID: PMC7235128.
      Citations: 2     Fields:    Translation:Humans
    49. Aryal NK, Pant V, Wasylishen AR, Rimel BJ, Baseler L, El-Naggar AK, Mutch DG, Goodfellow PJ, Arur S, Lozano G. Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination. Cancer Res. 2019 05 15; 79(10):2662-2668. PMID: 30914430; PMCID: PMC6522273.
      Citations: 2     Fields:    Translation:AnimalsCells
    50. Nikiforova MN, Nikitski AV, Panebianco F, Kaya C, Yip L, Williams M, Chiosea SI, Seethala RR, Roy S, Condello V, Santana-Santos L, Wald AI, Carty SE, Ferris RL, El-Naggar AK, Nikiforov YE. GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland. Thyroid. 2019 02; 29(2):161-173. PMID: 30648929; PMCID: PMC6389773.
      Citations: 21     Fields:    Translation:Humans
    51. Aryal NK, Pant V, Wasylishen AR, Parker-Thornburg J, Baseler L, El-Naggar AK, Liu B, Kalia A, Lozano G, Arur S. Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo. Proc Natl Acad Sci U S A. 2019 01 15; 116(3):960-969. PMID: 30593561; PMCID: PMC6338878.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    52. Ibrahim MY, Nunez MI, Harun N, Lee JJ, El-Naggar AK, Ferrarotto R, Wistuba I, Myers J, Glisson BS, William WN. PI3-kinase pathway biomarkers in oral cancer and tumor immune cells. Head Neck. 2019 03; 41(3):615-622. PMID: 30556200; PMCID: PMC6382518.
      Citations: 3     Fields:    Translation:HumansCells
    53. Zhang Y, Xiong S, Liu B, Pant V, Celii F, Chau G, Elizondo-Fraire AC, Yang P, You MJ, El-Naggar AK, Navin NE, Lozano G. Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases. Nat Commun. 2018 09 27; 9(1):3953. PMID: 30262850; PMCID: PMC6160420.
      Citations: 16     Fields:    Translation:HumansAnimals
    54. Mitani Y, Pytynia KB, Ferrarotto R, Roberts DB, Weber RS, Kies MS, Maity SN, Lin SH, El-Naggar AK, Saintigny P. Frequent PTEN loss and differential HER2/PI3K signaling pathway alterations in salivary duct carcinoma: Implications for targeted therapy. Cancer. 2018 09 15; 124(18):3693-3705. PMID: 30289966; PMCID: PMC6176717.
      Citations: 10     Fields:    Translation:HumansCells
    55. Ileana Dumbrava E, Smith V, Alfattal R, El-Naggar AK, Penas-Prado M, Tsimberidou AM. Autoimmune Granulomatous Inflammation of Lacrimal Glands and Axonal Neuritis Following Treatment With Ipilimumab and Radiation Therapy. J Immunother. 2018 09; 41(7):336-339. PMID: 29787423; PMCID: PMC6086752.
      Citations: 4     Fields:    Translation:Humans
    56. Klimstra DS, Abedi-Ardekani B, Asa SL, Bosman FT, Busam KJ, El-Naggar AK, Fernandez-Cuesta L, McCluggage WG, Moch H, Ohgaki H, Rakha EA, Reed NS, Rous BA, Sasano H, Scarpa A, Scoazec JY, Travis WD, Tallini G, van Krieken JH, Cree IA, Rindi G, Brambilla E, de Krijger RR, Dietel M, Kl?ppel G, Trouillas J. A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal. Mod Pathol. 2018 12; 31(12):1770-1786. PMID: 30140036; PMCID: PMC6265262.
      Citations: 249     Fields:    Translation:Humans
    57. Tam S, Sandulache VC, Metwalli KA, Rock CD, Eraj SA, Sheu T, El-Naggar AK, Fuller CD, Weber RS, Lai SY. Incompletely treated malignancies of the major salivary gland: Toward evidence-based care. Head Neck. 2018 08; 40(8):1630-1638. PMID: 29734482.
      Citations: 1     Fields:    Translation:Humans
    58. Kakudo K, El-Naggar AK, Hodak SP, Khanafshar E, Nikiforov YE, Thompson LDR, Nos? V. Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in thyroid tumor classification. Pathol Int. 2018 06; 68(6):327-333. PMID: 29675873.
      Citations: 10     Fields:    Translation:Humans
    59. William WN, Zhang L, Feng L, Kim ES, El-Naggar AK, Lee JJ, Mao L, Hong WK, Lingen MW, Lippman SM, Saintigny P, Foy JP, Papadimitrakopoulou V, Lang W, Fan YH. Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer. J Natl Cancer Inst. 2018 03 01; 110(3). PMID: 29617836; PMCID: PMC5946820.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    60. Mitani Y, Bell D, Mariano FV, Almalki ST, Pytynia KB, El-Naggar AK, Rito M, Fonseca I. Frequent and differential mutations of the CYLD gene in basal cell salivary neoplasms: linkage to tumor development and progression. Mod Pathol. 2018 07; 31(7):1064-1072. PMID: 29463883.
      Citations: 8     Fields:    Translation:Humans
    61. Slootweg PJ, El-Naggar AK. World Health Organization 4th edition of head and neck tumor classification: insight into the consequential modifications. Virchows Arch. 2018 03; 472(3):311-313. PMID: 29450648.
      Citations: 5     Fields:    Translation:Humans
    62. Larsson CA, Moyer SM, Liu B, Michel KA, Pant V, Yang P, Wong J, El-Naggar AK, Krahe R, Lozano G. Synergistic and additive effect of retinoic acid in circumventing resistance to p53 restoration. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):2198-2203. PMID: 29440484; PMCID: PMC5834709.
      Citations: 4     Fields:    Translation:AnimalsCells
    63. Kamal M, Ng SP, Eraj SA, Rock CD, Pham B, Messer JA, Garden AS, Morrison WH, Phan J, Frank SJ, El-Naggar AK, Johnson JM, Ginsberg LE, Ferrarotto R, Lewin JS, Hutcheson KA, Cardenas CE, Zafereo ME, Lai SY, Hessel AC, Weber RS, Gunn GB, Fuller CD, Mohamed ASR, Rosenthal DI. Three-dimensional imaging assessment of anatomic invasion and volumetric considerations for chemo/radiotherapy-based laryngeal preservation in T3 larynx cancer. Oral Oncol. 2018 04; 79:1-8. PMID: 29598944; PMCID: PMC5880303.
      Citations: 2     Fields:    Translation:Humans
    64. Frerich CA, Brayer KJ, Painter BM, Kang H, Mitani Y, El-Naggar AK, Ness SA. Transcriptomes define distinct subgroups of salivary gland adenoid cystic carcinoma with different driver mutations and outcomes. Oncotarget. 2018 Jan 26; 9(7):7341-7358. PMID: 29484115; PMCID: PMC5800907.
      Citations: 9     Fields:    
    65. Saluja K, Thomas J, Zhang S, Sturgis EM, Jain KS, Prieto VG, El-Naggar AK, Bell D. Malignant perivascular epithelioid cell tumor of the oropharynx with strong TFE3 expression mimicking alveolar soft part sarcoma: a case report and review of the literature. Hum Pathol. 2018 06; 76:149-155. PMID: 29208563.
      Citations: 4     Fields:    Translation:Humans
    66. Thakar SD, Sagiv O, Tetzlaff MT, El-Naggar A, Debnam JM, Kandl TJ, Esmaeli B. A 60-year-old woman with an asymptomatic left lacrimal gland mass found incidentally. Digit J Ophthalmol. 2017; 23(4):27-29. PMID: 29403339; PMCID: PMC5791630.
      Citations:    Fields:    Translation:Humans
    67. Wang J, Xie T, Wang B, William WN, Heymach JV, El-Naggar AK, Myers JN, Caulin C. PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions. Cancer Prev Res (Phila). 2017 Dec; 10(12):684-693. PMID: 29018057; PMCID: PMC5716880.
      Citations: 23     Fields:    Translation:AnimalsCells
    68. Liu B, Mitani Y, Rao X, Zafereo M, Zhang J, Zhang J, Futreal PA, Lozano G, El-Naggar AK. Spatio-Temporal Genomic Heterogeneity, Phylogeny, and Metastatic Evolution in Salivary Adenoid Cystic Carcinoma. J Natl Cancer Inst. 2017 10 01; 109(10). PMID: 29117356; PMCID: PMC6059240.
      Citations: 11     Fields:    Translation:Humans
    69. Zhang H, Kim S, Chen Z, Nannapaneni S, Chen AY, Moore CE, Sica G, Mosunjac M, Nguyen MLT, D'Souza G, Carey TE, Peterson LA, McHugh JB, Graham M, Komarck CM, Wolf GT, Walline HM, Bellile E, Riddell J, Pai SI, Sidransky D, Westra WH, William WN, Lee JJ, El-Naggar AK, Ferris RL, Seethala R, Grandis JR, Chen ZG, Saba NF, Shin DM, Head and Neck Cancer SPORE HIV supplement consortium. Prognostic biomarkers in patients with human immunodeficiency virus-positive disease with head and neck squamous cell carcinoma. Head Neck. 2017 12; 39(12):2433-2443. PMID: 28945296; PMCID: PMC5808949.
      Citations: 2     Fields:    Translation:Humans
    70. Ortiz GJ, Li Y, Post SM, Pant V, Xiong S, Larsson CA, El-Naggar AK, Johnson DG, Lozano G. Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes. Oncogene. 2018 01 18; 37(3):332-340. PMID: 28925402; PMCID: PMC5775049.
      Citations: 6     Fields:    Translation:AnimalsCells
    71. Jiffar T, Yilmaz T, Lee J, Miller Y, Feng L, El-Naggar A, Kupferman ME. Brain derived neutrophic factor (BDNF) coordinates lympho-vascular metastasis through a fibroblast-governed paracrine axis in the tumor microenvironment. Cancer Cell Microenviron. 2017; 4(2). PMID: 28966935; PMCID: PMC5617346.
      Citations: 5     
    72. Rosenthal DI, Mohamed ASR, Garden AS, Morrison WH, El-Naggar AK, Kamal M, Weber RS, Fuller CD, Peters LJ. Final Report of a Prospective Randomized Trial to Evaluate the Dose-Response Relationship for Postoperative Radiation Therapy and Pathologic Risk Groups in Patients With Head and Neck?Cancer. Int J Radiat Oncol Biol Phys. 2017 08 01; 98(5):1002-1011. PMID: 28721881; PMCID: PMC5518636.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    73. El-Naggar AK. What Is New in the World Health Organization 2017 Histopathology Classification? Curr Treat Options Oncol. 2017 07; 18(7):43. PMID: 28639231.
      Citations: 2     Fields:    Translation:Humans
    74. El-Naggar AK, Chan JKC, Takata T, Grandis JR, Slootweg PJ. The fourth edition of the head and neck World Health Organization blue book: editors' perspectives. Hum Pathol. 2017 08; 66:10-12. PMID: 28583885.
      Citations: 36     Fields:    Translation:Humans
    75. Bell D, El-Naggar AK, Gidley PW. Middle ear adenomatous neuroendocrine tumors: a 25-year experience at MD Anderson Cancer Center. Virchows Arch. 2017 Nov; 471(5):667-672. PMID: 28547535.
      Citations: 11     Fields:    Translation:Humans
    76. Saluja K, Butler RT, Pytynia KB, Zhao B, Karni RJ, Weber RS, El-Naggar AK. Mucoepidermoid carcinoma post-radioactive iodine treatment of papillary thyroid carcinoma: unique presentation and putative etiologic association. Hum Pathol. 2017 10; 68:189-192. PMID: 28499545.
      Citations: 1     Fields:    Translation:HumansCells
    77. Li J, Mitani Y, Rao PH, Perlaky L, Liu B, Weber RS, El-Naggar AK. Establishment and genomic characterization of primary salivary duct carcinoma cell line. Oral Oncol. 2017 06; 69:108-114. PMID: 28559013; PMCID: PMC5531198.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    78. El-Naggar AK. Editor's perspective on the 4th edition of the WHO head and neck tumor classification. J Egypt Natl Canc Inst. 2017 06; 29(2):65-66. PMID: 28455004.
      Citations: 3     Fields:    Translation:Humans
    79. Weidhaas JB, Harris J, Chen AM, Chin R, Axelrod R, El-Naggar AK, Singh AK, Galloway TJ, Raben D, Wang D, Matthiesen C, Avizonis VN, Manon RR, Yumen O, Trotti A, Skinner H, Zhang Q, Ferris RL, Sidransky D, Chung CH, Schaue D, Nguyen-Tan PF. The KRAS-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer: A Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2017 Apr 01; 3(4):483-491. PMID: 28006059; PMCID: PMC5470422.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    80. Salem A, Bell D, Sepesi B, Papadimitrakopoulou V, El-Naggar A, Moran CA, Kalhor N. Clinicopathologic and genetic features of primary bronchopulmonary mucoepidermoid carcinoma: the MD Anderson Cancer Center experience and comprehensive review of the literature. Virchows Arch. 2017 Jun; 470(6):619-626. PMID: 28343305.
      Citations: 8     Fields:    Translation:Humans
    81. Panaccione A, Zhang Y, Mi Y, Mitani Y, Yan G, Prasad ML, McDonald WH, El-Naggar AK, Yarbrough WG, Ivanov SV. Chromosomal abnormalities and molecular landscape of metastasizing mucinous salivary adenocarcinoma. Oral Oncol. 2017 03; 66:38-45. PMID: 28249646; PMCID: PMC5335866.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    82. Ferrarotto R, Mitani Y, Diao L, Guijarro I, Wang J, Zweidler-McKay P, Bell D, William WN, Glisson BS, Wick MJ, Kapoun AM, Patnaik A, Eckhardt G, Munster P, Faoro L, Dupont J, Lee JJ, Futreal A, El-Naggar AK, Heymach JV. Activating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors. J Clin Oncol. 2017 Jan 20; 35(3):352-360. PMID: 27870570; PMCID: PMC5456373.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    83. Li Z, Gonzalez CL, Wang B, Zhang Y, Mejia O, Katsonis P, Lichtarge O, Myers JN, El-Naggar AK, Caulin C. Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53(R172H). J Pathol. 2016 10; 240(2):224-34. PMID: 27447534; PMCID: PMC8570672.
      Citations: 17     Fields:    Translation:HumansAnimals
    84. El-Naggar AK. HPV and oropharyngeal cancer mystery: a glimmer of hope! Oral Dis. 2016 11; 22(8):715. PMID: 27095118.
      Citations:    Fields:    Translation:HumansCells
    85. Truong MT, Zhang Q, Rosenthal DI, List M, Axelrod R, Sherman E, Weber R, El-Naggar A, Galvin J, Schwartz D, Trotti A, Silverman C, Singh A, Godette K, Bonner JA, Jones CU, Garden AS, Matthiesen C, Le QT, Bruner D, Nguyen-T?n PF, Konski A, Shenouda G. Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522. Int J Radiat Oncol Biol Phys. 2017 03 15; 97(4):687-699. PMID: 27727066; PMCID: PMC5303682.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    86. Nikiforov YE, Seethala RR, Tallini G, Baloch ZW, Basolo F, Thompson LD, Barletta JA, Wenig BM, Al Ghuzlan A, Kakudo K, Giordano TJ, Alves VA, Khanafshar E, Asa SL, El-Naggar AK, Gooding WE, Hodak SP, Lloyd RV, Maytal G, Mete O, Nikiforova MN, Papotti M, Poller DN, Sadow PM, Tischler AS, Tuttle RM, Wall KB, LiVolsi VA, Randolph GW, Ghossein RA, Nos? V. Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma: A Paradigm Shift to Reduce Overtreatment of Indolent Tumors. JAMA Oncol. 2016 08 01; 2(8):1023-9. PMID: 27078145; PMCID: PMC5539411.
      Citations: 339     Fields:    Translation:Humans
    87. Fuller CD, Mohamed AS, Garden AS, Gunn GB, Mulcahy CF, Zafereo M, Phan J, Lai SY, Lewin JS, Hutcheson KA, Frank SJ, Beadle BM, Morrison WH, El-Naggar AK, Kocak-Uzel E, Ginsberg LE, Kies MS, Weber RS, Rosenthal DI. Long-term outcomes after multidisciplinary management of T3 laryngeal squamous cell carcinomas: Improved functional outcomes and survival with modern therapeutic approaches. Head Neck. 2016 12; 38(12):1739-1751. PMID: 27466789; PMCID: PMC5539952.
      Citations: 9     Fields:    Translation:Humans
    88. Sridharan V, Gjini E, Liao X, Chau NG, Haddad RI, Severgnini M, Hammerman P, El-Naggar A, Freeman GJ, Hodi FS, Rodig SJ, Dranoff G, Schoenfeld JD. Immune Profiling of Adenoid Cystic Carcinoma: PD-L2 Expression and Associations with Tumor-Infiltrating Lymphocytes. Cancer Immunol Res. 2016 08; 4(8):679-87. PMID: 27312343.
      Citations: 25     Fields:    Translation:HumansCells
    89. Saluja K, Rao PH, Myers JN, El-Naggar AK. Novel t(1;3)(q21,p21) translocation in a basal cell adenocarcinoma of the parotid gland: potential association with tumorigenesis. Hum Pathol. 2016 08; 54:189-92. PMID: 27085552.
      Citations: 1     Fields:    Translation:HumansCells
    90. Skinner HD, Giri U, Yang L, Woo SH, Story MD, Pickering CR, Byers LA, Williams MD, El-Naggar A, Wang J, Diao L, Shen L, Fan YH, Molkentine DP, Beadle BM, Meyn RE, Myers JN, Heymach JV. Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer. Clin Cancer Res. 2016 Sep 15; 22(18):4643-50. PMID: 27036135; PMCID: PMC5061056.
      Citations: 27     Fields:    Translation:HumansCells
    91. Zafereo ME, Xu L, Dahlstrom KR, Viamonte CA, El-Naggar AK, Wei Q, Li G, Sturgis EM. Squamous cell carcinoma of the oral cavity often overexpresses p16 but is rarely driven by human papillomavirus. Oral Oncol. 2016 May; 56:47-53. PMID: 27086486; PMCID: PMC4836441.
      Citations: 34     Fields:    Translation:HumansCells
    92. Takiar V, Garden AS, Ma D, Morrison WH, Edson M, Zafereo ME, Gunn GB, Fuller CD, Beadle B, Frank SJ, William WN, Kies M, El-Naggar AK, Weber R, Rosenthal DI, Phan J. Reirradiation of Head and Neck Cancers With Intensity Modulated Radiation Therapy: Outcomes and Analyses. Int J Radiat Oncol Biol Phys. 2016 07 15; 95(4):1117-31. PMID: 27354127.
      Citations: 37     Fields:    Translation:Humans
    93. William WN, Papadimitrakopoulou V, Lee JJ, Mao L, Cohen EE, Lin HY, Gillenwater AM, Martin JW, Lingen MW, Boyle JO, Shin DM, Vigneswaran N, Shinn N, Heymach JV, Wistuba II, Tang X, Kim ES, Saintigny P, Blair EA, Meiller T, Gutkind JS, Myers J, El-Naggar A, Lippman SM. Erlotinib and the Risk of Oral Cancer: The Erlotinib Prevention of Oral Cancer (EPOC) Randomized Clinical Trial. JAMA Oncol. 2016 Feb; 2(2):209-16. PMID: 26540028; PMCID: PMC4771491.
      Citations: 51     Fields:    Translation:Humans
    94. Drier Y, Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L, Qi J, Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster JC, Knoechel B, Bernstein BE. An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma. Nat Genet. 2016 Mar; 48(3):265-72. PMID: 26829750; PMCID: PMC4767593.
      Citations: 100     Fields:    Translation:HumansCells
    95. Mitani Y, Liu B, Rao PH, Borra VJ, Zafereo M, Weber RS, Kies M, Lozano G, Futreal PA, Caulin C, El-Naggar AK. Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations. Clin Cancer Res. 2016 Feb 01; 22(3):725-33. PMID: 26631609; PMCID: PMC4807116.
      Citations: 61     Fields:    Translation:HumansCells
    96. Nien HH, Sturgis EM, Kies MS, El-Naggar AK, Morrison WH, Beadle BM, Johnson FM, Gunn GB, Fuller CD, Phan J, Gold KA, Frank SJ, Skinner H, Rosenthal DI, Garden AS. Comparison of systemic therapies used concurrently with radiation for the treatment of human papillomavirus-associated oropharyngeal cancer. Head Neck. 2016 04; 38 Suppl 1:E1554-61. PMID: 26595157.
      Citations: 6     Fields:    Translation:HumansCells
    97. Jiang W, Chamberlain PD, Garden AS, Kim BY, Ma D, Lo EJ, Bell D, Gunn GB, Fuller CD, Rosenthal DI, Beadle BM, Frank SJ, Morrison WH, El-Naggar AK, Glisson BS, Sturgis EM, Phan J. Prognostic value of p16 expression in Epstein-Barr virus-positive nasopharyngeal carcinomas. Head Neck. 2016 04; 38 Suppl 1:E1459-66. PMID: 26560893; PMCID: PMC5903429.
      Citations: 6     Fields:    Translation:HumansCells
    98. Jiang W, Mohamed ASR, Fuller CD, Kim BYS, Tang C, Gunn GB, Hanna EY, Frank SJ, Su SY, Diaz E, Kupferman ME, Beadle BM, Morrison WH, Skinner H, Lai SY, El-Naggar AK, DeMonte F, Rosenthal DI, Garden AS, Phan J. The role of elective nodal irradiation for esthesioneuroblastoma patients with clinically negative neck. Pract Radiat Oncol. 2016 Jul-Aug; 6(4):241-247. PMID: 26979544; PMCID: PMC5286455.
      Citations: 10     Fields:    Translation:Humans
    99. Perrier ND, El-Naggar AK. Editorial: How clinically significant is minimal extrathyroidal extension in papillary thyroid cancer? Surgery. 2016 Jan; 159(1):22. PMID: 26518390.
      Citations:    Fields:    Translation:Humans
    100. Wang Z, Ling S, Rettig E, Sobel R, Tan M, Fertig EJ, Considine M, El-Naggar AK, Brait M, Fakhry C, Ha PK. Epigenetic screening of salivary gland mucoepidermoid carcinoma identifies hypomethylation of CLIC3 as a common alteration. Oral Oncol. 2015 Dec; 51(12):1120-5. PMID: 26490796; PMCID: PMC4663116.
      Citations: 5     Fields:    Translation:HumansCells
    101. Ragab Y, Nabih M, Aly I, Kamal A, Abd-Allah MA, El-Refai R, Emad Y, El-Naggar A, El-Shaarawy N, Rasker JJ. Magnetic resonance imaging features of hip disorders in an Egyptian pediatric population. Reumatismo. 2015 Sep 16; 67(2):68-77. PMID: 26492965.
      Citations: 3     Fields:    Translation:Humans
    102. Pickering CR, Papadimitrakopoulou VA, Jelinek J, Lin SH, William WN, Frederick MJ, Wang J, Lang W, Feng L, Zhang L, Kim ES, Fan YH, Hong WK, El-Naggar AK, Lee JJ, Myers JN, Issa JP, Lippman SM, Mao L, Foy JP, Saintigny P. New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development. Cancer Prev Res (Phila). 2015 Nov; 8(11):1027-35. PMID: 26342026; PMCID: PMC4777304.
      Citations: 27     Fields:    Translation:HumansCells
    103. Bell D, Lewis C, El-Naggar AK, Weber RS. Primary intraosseous mucoepidermoid carcinoma of the jaw: Reappraisal of The MD Anderson Cancer Center experience. Head Neck. 2016 04; 38 Suppl 1:E1312-7. PMID: 26316332.
      Citations: 9     Fields:    Translation:Humans
    104. Takiar V, Ma D, Garden AS, Li J, Rosenthal DI, Beadle BM, Frank SJ, Fuller CD, Gunn GB, Morrison WH, Hutcheson K, El-Naggar AK, Gold KA, Kupferman ME, Phan J. Disease control and toxicity outcomes for T4 carcinoma of the nasopharynx treated with intensity-modulated radiotherapy. Head Neck. 2016 04; 38 Suppl 1:E925-33. PMID: 25994561.
      Citations: 9     Fields:    Translation:Humans
    105. Xu L, Tang H, El-Naggar AK, Wei P, Sturgis EM. Genetic variants in DNA double-strand break repair genes and risk of salivary gland carcinoma: a case-control study. PLoS One. 2015; 10(6):e0128753. PMID: 26035306; PMCID: PMC4452711.
      Citations: 2     Fields:    Translation:HumansCells
    106. Bell D, Ferrarotto R, Fox MD, Roberts D, Hanna EY, Weber RS, El-Naggar AK. Analysis and significance of c-MET expression in adenoid cystic carcinoma of the salivary gland. Cancer Biol Ther. 2015; 16(6):834-8. PMID: 25923130; PMCID: PMC4622840.
      Citations: 1     Fields:    Translation:Humans
    107. Huang AT, Tang C, Bell D, Yener M, Izquierdo L, Frank SJ, El-Naggar AK, Hanna EY, Weber RS, Kupferman ME. Prognostic factors in adenocarcinoma of the salivary glands. Oral Oncol. 2015 Jun; 51(6):610-5. PMID: 25843792.
      Citations: 7     Fields:    Translation:Humans
    108. Fakhry C, Zhang Q, Rosenthal D, El-Naggar AK, Garden AS, Trotti A, Avizonis VN, Ridge JA, Harris J, Le QT, Gillison M, Nguyen-Tan PF, Soulieres D. Reply to B. O'Sullivan et Al. J Clin Oncol. 2015 May 20; 33(15):1708-9. PMID: 25823732.
      Citations: 5     Fields:    Translation:HumansCells
    109. Xu L, Tang H, Chen DW, El-Naggar AK, Wei P, Sturgis EM. Genome-wide association study identifies common genetic variants associated with salivary gland carcinoma and its subtypes. Cancer. 2015 Jul 15; 121(14):2367-74. PMID: 25823930; PMCID: PMC4564998.
      Citations: 7     Fields:    Translation:HumansCells
    110. Jakob JA, Kies MS, Glisson BS, Kupferman ME, Liu DD, Lee JJ, El-Naggar AK, Gonzalez-Angulo AM, Blumenschein GR. Phase II study of gefitinib in patients with advanced salivary gland cancers. Head Neck. 2015 May; 37(5):644-9. PMID: 24585506; PMCID: PMC5669372.
      Citations: 28     Fields:    Translation:HumansCTClinical Trials
    111. William WN, El-Naggar AK. A novel target for oral cancer chemoprevention? Notch quite, yet?. Cancer Prev Res (Phila). 2015 Apr; 8(4):262-5. PMID: 25712052; PMCID: PMC4383667.
      Citations: 2     Fields:    Translation:Humans
    112. Osman AA, Neskey DM, Katsonis P, Patel AA, Ward AM, Hsu TK, Hicks SC, McDonald TO, Ow TJ, Alves MO, Pickering CR, Skinner HD, Zhao M, Sturgis EM, Kies MS, El-Naggar A, Perrone F, Licitra L, Bossi P, Kimmel M, Frederick MJ, Lichtarge O, Myers JN. Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients. Cancer Res. 2015 Apr 01; 75(7):1205-15. PMID: 25691460; PMCID: PMC4615655.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    113. Quiroga-Garza G, Lee JH, El-Naggar A, Black JO, Amrikachi M, Zhai QJ, Ayala AG, Ro JY. Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: more aggressive than previously reported. Hum Pathol. 2015 May; 46(5):725-31. PMID: 25754017.
      Citations: 9     Fields:    Translation:Humans
    114. Su YX, Roberts DB, Hanna EY, El-Naggar A, Frank SJ, Weber RS, Kupferman ME, Saylam G. Risk Factors and Prognosis for Myoepithelial Carcinoma of the Major Salivary Glands. Ann Surg Oncol. 2015 Oct; 22(11):3701-7. PMID: 25636455.
      Citations: 3     Fields:    Translation:Humans
    115. Neskey DM, Osman AA, Ow TJ, Katsonis P, McDonald T, Hicks SC, Hsu TK, Pickering CR, Ward A, Patel A, Yordy JS, Skinner HD, Giri U, Sano D, Story MD, Beadle BM, El-Naggar AK, Kies MS, William WN, Caulin C, Frederick M, Kimmel M, Myers JN, Lichtarge O. Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer. Cancer Res. 2015 Apr 01; 75(7):1527-36. PMID: 25634208; PMCID: PMC4383697.
      Citations: 80     Fields:    Translation:HumansCells
    116. Rosenthal DI, Mohamed AS, Weber RS, Garden AS, Sevak PR, Kies MS, Morrison WH, Lewin JS, El-Naggar AK, Ginsberg LE, Kocak-Uzel E, Ang KK, Fuller CD. Long-term outcomes after surgical or nonsurgical initial therapy for patients with T4 squamous cell carcinoma of the larynx: A 3-decade survey. Cancer. 2015 May 15; 121(10):1608-19. PMID: 25586197; PMCID: PMC4424158.
      Citations: 35     Fields:    Translation:Humans
    117. Shi X, Liu R, Qu S, Zhu G, Bishop J, Liu X, Sun H, Shan Z, Wang E, Luo Y, Yang X, Zhao J, Du J, El-Naggar AK, Teng W, Xing M. Association of TERT promoter mutation 1,295,228 C>T with BRAF V600E mutation, older patient age, and distant metastasis in anaplastic thyroid cancer. J Clin Endocrinol Metab. 2015 Apr; 100(4):E632-7. PMID: 25584719; PMCID: PMC4399285.
      Citations: 38     Fields:    Translation:HumansCells
    118. Yu YH, Morales J, Feng L, Lee JJ, El-Naggar AK, Vigneswaran N. CD147 and Ki-67 overexpression confers poor prognosis in squamous cell carcinoma of oral tongue: a tissue microarray study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 May; 119(5):553-65. PMID: 25747176; PMCID: PMC4397137.
      Citations: 17     Fields:    Translation:Humans
    119. Gao R, Cao C, Zhang M, Lopez MC, Yan Y, Chen Z, Mitani Y, Zhang L, Zajac-Kaye M, Liu B, Wu L, Renne R, Baker HV, El-Naggar A, Kaye FJ. A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets. Oncotarget. 2014 Dec 30; 5(24):12528-42. PMID: 25587024; PMCID: PMC4350357.
      Citations: 19     Fields:    Translation:HumansAnimals
    120. Henderson YC, Ahn SH, Ryu J, Chen Y, Williams MD, El-Naggar AK, Gagea M, Schweppe RE, Haugen BR, Lai SY, Clayman GL. Development and characterization of six new human papillary thyroid carcinoma cell lines. J Clin Endocrinol Metab. 2015 Feb; 100(2):E243-52. PMID: 25427145; PMCID: PMC4318904.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    121. El-Naggar AK. John G. Batsakis, MD (1929-2013): a historical perspective on his contributions to pathology. Arch Pathol Lab Med. 2014 Nov; 138(11):1424. PMID: 25357103.
      Citations:    Fields:    Translation:Humans
    122. Mitani Y, Rao PH, Maity SN, Lee YC, Ferrarotto R, Post JC, Licitra L, Lippman SM, Kies MS, Weber RS, Caulin C, Lin SH, El-Naggar AK. Alterations associated with androgen receptor gene activation in salivary duct carcinoma of both sexes: potential therapeutic ramifications. Clin Cancer Res. 2014 Dec 15; 20(24):6570-81. PMID: 25316813; PMCID: PMC4268116.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    123. Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, Ren X, Zhang J, Pantazi A, Santoso N, Xu AW, Mahadeshwar H, Wheeler DA, Haddad RI, Jung J, Ojesina AI, Issaeva N, Yarbrough WG, Hayes DN, Grandis JR, El-Naggar AK, Meyerson M, Park PJ, Chin L, Seidman JG, Hammerman PS, Kucherlapati R, Cancer Genome Atlas Network. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15544-9. PMID: 25313082; PMCID: PMC4217452.
      Citations: 156     Fields:    Translation:HumansCells
    124. Pickering CR, Zhou JH, Lee JJ, Drummond JA, Peng SA, Saade RE, Tsai KY, Curry JL, Tetzlaff MT, Lai SY, Yu J, Muzny DM, Doddapaneni H, Shinbrot E, Covington KR, Zhang J, Seth S, Caulin C, Clayman GL, El-Naggar AK, Gibbs RA, Weber RS, Myers JN, Wheeler DA, Frederick MJ. Mutational landscape of aggressive cutaneous squamous cell carcinoma. Clin Cancer Res. 2014 Dec 15; 20(24):6582-92. PMID: 25303977; PMCID: PMC4367811.
      Citations: 210     Fields:    Translation:Humans
    125. Ju YS, Alexandrov LB, Gerstung M, Martincorena I, Nik-Zainal S, Ramakrishna M, Davies HR, Papaemmanuil E, Gundem G, Shlien A, Bolli N, Behjati S, Tarpey PS, Nangalia J, Massie CE, Butler AP, Teague JW, Vassiliou GS, Green AR, Du MQ, Unnikrishnan A, Pimanda JE, Teh BT, Munshi N, Greaves M, Vyas P, El-Naggar AK, Santarius T, Collins VP, Grundy R, Taylor JA, Hayes DN, Malkin D, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Foster CS, Warren AY, Whitaker HC, Brewer D, Eeles R, Cooper C, Neal D, Visakorpi T, Isaacs WB, Bova GS, Flanagan AM, Futreal PA, Lynch AG, Chinnery PF, McDermott U, Stratton MR, Campbell PJ. Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer. Elife. 2014 Oct 01; 3. PMID: 25271376; PMCID: PMC4371858.
      Citations: 153     Fields:    Translation:HumansAnimalsCells
    126. Ang KK, Zhang Q, Rosenthal DI, Nguyen-Tan PF, Sherman EJ, Weber RS, Galvin JM, Bonner JA, Harris J, El-Naggar AK, Gillison ML, Jordan RC, Konski AA, Thorstad WL, Trotti A, Beitler JJ, Garden AS, Spanos WJ, Yom SS, Axelrod RS. Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522. J Clin Oncol. 2014 Sep 20; 32(27):2940-50. PMID: 25154822; PMCID: PMC4162493.
      Citations: 301     Fields:    Translation:HumansCTClinical Trials
    127. Gillenwater AM, Vigneswaran N, Fatani H, Saintigny P, El-Naggar AK. Proliferative verrucous leukoplakia: recognition and differentiation from conventional leukoplakia and mimics. Head Neck. 2014 Nov; 36(11):1662-8. PMID: 24115154.
      Citations: 8     Fields:    Translation:Humans
    128. Li J, Perlaky L, Rao P, Weber RS, El-Naggar AK. Development and characterization of salivary adenoid cystic carcinoma cell line. Oral Oncol. 2014 Oct; 50(10):991-9. PMID: 25086988; PMCID: PMC4573592.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    129. Xiong S, Tu H, Kollareddy M, Pant V, Li Q, Zhang Y, Jackson JG, Suh YA, Elizondo-Fraire AC, Yang P, Chau G, Tashakori M, Wasylishen AR, Ju Z, Solomon H, Rotter V, Liu B, El-Naggar AK, Donehower LA, Martinez LA, Lozano G. Pla2g16 phospholipase mediates gain-of-function activities of mutant p53. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):11145-50. PMID: 25024203; PMCID: PMC4121829.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    130. Fakhry C, Zhang Q, Nguyen-Tan PF, Rosenthal D, El-Naggar A, Garden AS, Soulieres D, Trotti A, Avizonis V, Ridge JA, Harris J, Le QT, Gillison M. Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma. J Clin Oncol. 2014 Oct 20; 32(30):3365-73. PMID: 24958820; PMCID: PMC4195851.
      Citations: 151     Fields:    Translation:HumansCells
    131. Garden AS, Gunn GB, Hessel A, Beadle BM, Ahmed S, El-Naggar AK, Fuller CD, Byers LA, Phan J, Frank SJ, Morrison WH, Kies MS, Rosenthal DI, Sturgis EM. Management of the lymph node-positive neck in the patient with human papillomavirus-associated oropharyngeal cancer. Cancer. 2014 Oct 01; 120(19):3082-8. PMID: 24898672; PMCID: PMC4172550.
      Citations: 8     Fields:    Translation:HumansCells
    132. Pickering CR, Zhang J, Neskey DM, Zhao M, Jasser SA, Wang J, Ward A, Tsai CJ, Ortega Alves MV, Zhou JH, Drummond J, El-Naggar AK, Gibbs R, Weinstein JN, Wheeler DA, Wang J, Frederick MJ, Myers JN. Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers. Clin Cancer Res. 2014 Jul 15; 20(14):3842-8. PMID: 24874835; PMCID: PMC4102633.
      Citations: 56     Fields:    Translation:Humans
    133. Li Q, Zhang Y, El-Naggar AK, Xiong S, Yang P, Jackson JG, Chau G, Lozano G. Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors. Mol Cancer Res. 2014 Jun; 12(6):901-11. PMID: 24598047; PMCID: PMC4058386.
      Citations: 17     Fields:    Translation:AnimalsCells
    134. Savar A, Acin S, Gonzalez CL, El-Sawy T, Mejia O, Li Z, Esmaeli B, Lacy-Hulbert A, El-Naggar AK, McCarty JH, Caulin C. Loss of epithelial p53 and av integrin cooperate through Akt to induce squamous cell carcinoma yet prevent remodeling of the tumor microenvironment. Oncogene. 2015 Jan 22; 34(4):516-24. PMID: 24469034; PMCID: PMC4303549.
      Citations: 12     Fields:    Translation:AnimalsCells
    135. Bell D, Holsinger FC, Ordonez N, El-Naggar AK. Intestinal-type adenocarcinoma of the larynx: Report of a rare aggressive phenotype and discussion of histogenesis. Head Neck. 2014 May; 36(5):E44-7. PMID: 24038722.
      Citations: 2     Fields:    Translation:Humans
    136. Neskey DM, Klein JD, Hicks S, Garden AS, Bell DM, El-Naggar AK, Kies MS, Weber RS, Kupferman ME. Prognostic factors associated with decreased survival in patients with acinic cell carcinoma. JAMA Otolaryngol Head Neck Surg. 2013 Nov; 139(11):1195-202. PMID: 24076756; PMCID: PMC5555308.
      Citations: 12     Fields:    Translation:Humans
    137. Vigneswaran N, Fatani H, Saintigny P, El-Naggar AK, Gillenwater AM. Proliferative verrucous leukoplakia (PVL): a review of an elusive pathologic entity! Adv Anat Pathol. 2013 Nov; 20(6):416-23. PMID: 24113312.
      Citations: 6     Fields:    Translation:Humans
    138. Takahashi Y, Bell D, Agarwal G, Roberts D, Xie TX, El-Naggar A, Myers JN, Hanna EY. Comprehensive assessment of prognostic markers for sinonasal squamous cell carcinoma. Head Neck. 2014 Aug; 36(8):1094-102. PMID: 23836481.
      Citations: 11     Fields:    Translation:Humans
    139. Santarpia L, Calin GA, Adam L, Ye L, Fusco A, Giunti S, Thaller C, Paladini L, Zhang X, Jimenez C, Trimarchi F, El-Naggar AK, Gagel RF. A miRNA signature associated with human metastatic medullary thyroid carcinoma. Endocr Relat Cancer. 2013 Dec; 20(6):809-23. PMID: 24127332.
      Citations: 39     Fields:    Translation:HumansCells
    140. Bell D, Hanna EY, Miele L, Roberts D, Weber RS, El-Naggar AK. Expression and significance of notch signaling pathway in salivary adenoid cystic carcinoma. Ann Diagn Pathol. 2014 Feb; 18(1):10-3. PMID: 24238845; PMCID: PMC4807115.
      Citations: 14     Fields:    Translation:HumansCells
    141. Milbury K, Rosenthal DI, El-Naggar A, Badr H. An exploratory study of the informational and psychosocial needs of patients with human papillomavirus-associated oropharyngeal cancer. Oral Oncol. 2013 Nov; 49(11):1067-71. PMID: 23953777; PMCID: PMC3964874.
      Citations: 18     Fields:    Translation:HumansCells
    142. El-Naggar AK, Kaye FJ, Stenman G. The 3rd Salivary Gland Tumor Workshop meeting report. Head Neck. 2013 Aug; 35(8):1057-60. PMID: 23677839.
      Citations: 1     Fields:    Translation:Humans
    143. Millare GG, Guha-Thakurta N, Sturgis EM, El-Naggar AK, Debnam JM. Imaging findings of head and neck dermatofibrosarcoma protuberans. AJNR Am J Neuroradiol. 2014 Feb; 35(2):373-8. PMID: 23907249; PMCID: PMC7965745.
      Citations: 8     Fields:    Translation:Humans
    144. Liu X, Bishop J, Shan Y, Pai S, Liu D, Murugan AK, Sun H, El-Naggar AK, Xing M. Highly prevalent TERT promoter mutations in aggressive thyroid cancers. Endocr Relat Cancer. 2013 Aug; 20(4):603-10. PMID: 23766237; PMCID: PMC3782569.
      Citations: 219     Fields:    Translation:HumansCells
    145. Mitani Y, Roberts DB, Fatani H, Weber RS, Kies MS, Lippman SM, El-Naggar AK. MicroRNA profiling of salivary adenoid cystic carcinoma: association of miR-17-92 upregulation with poor outcome. PLoS One. 2013; 8(6):e66778. PMID: 23825564; PMCID: PMC3692530.
      Citations: 16     Fields:    Translation:HumansCells
    146. Ow TJ, Hanna EY, Roberts DB, Levine NB, El-Naggar AK, Rosenthal DI, DeMonte F, Kupferman ME. Optimization of long-term outcomes for patients with esthesioneuroblastoma. Head Neck. 2014 Apr; 36(4):524-30. PMID: 23780581.
      Citations: 32     Fields:    Translation:Humans
    147. Stephens PJ, Davies HR, Mitani Y, Van Loo P, Shlien A, Tarpey PS, Papaemmanuil E, Cheverton A, Bignell GR, Butler AP, Gamble J, Gamble S, Hardy C, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, McLaren S, McBride DJ, Menzies A, Mudie L, Maddison M, Raine K, Nik-Zainal S, O'Meara S, Teague JW, Varela I, Wedge DC, Whitmore I, Lippman SM, McDermott U, Stratton MR, Campbell PJ, El-Naggar AK, Futreal PA. Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest. 2013 Jul; 123(7):2965-8. PMID: 23778141; PMCID: PMC3999050.
      Citations: 109     Fields:    Translation:Humans
    148. Perissinotti AJ, Lee Pierce M, Pace MB, El-Naggar A, Kies MS, Kupferman M. The role of trastuzumab in the management of salivary ductal carcinomas. Anticancer Res. 2013 Jun; 33(6):2587-91. PMID: 23749912.
      Citations: 12     Fields:    Translation:Humans
    149. Cockerill CC, Daram S, El-Naggar AK, Hanna EY, Weber RS, Kupferman ME. Primary sarcomas of the salivary glands: case series and literature review. Head Neck. 2013 Nov; 35(11):1551-7. PMID: 23728801.
      Citations: 4     Fields:    Translation:Humans
    150. Gelbard A, Hale KS, Takahashi Y, Davies M, Kupferman ME, El-Naggar AK, Myers JN, Hanna EY. Molecular profiling of sinonasal undifferentiated carcinoma. Head Neck. 2014 Jan; 36(1):15-21. PMID: 23633104; PMCID: PMC3874284.
      Citations: 5     Fields:    Translation:Humans
    151. Pickering CR, Zhang J, Yoo SY, Bengtsson L, Moorthy S, Neskey DM, Zhao M, Ortega Alves MV, Chang K, Drummond J, Cortez E, Xie TX, Zhang D, Chung W, Issa JP, Zweidler-McKay PA, Wu X, El-Naggar AK, Weinstein JN, Wang J, Muzny DM, Gibbs RA, Wheeler DA, Myers JN, Frederick MJ. Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov. 2013 Jul; 3(7):770-81. PMID: 23619168; PMCID: PMC3858325.
      Citations: 241     Fields:    Translation:HumansCells
    152. Zhang L, Mitani Y, Caulin C, Rao PH, Kies MS, Saintigny P, Zhang N, Weber RS, Lippman SM, El-Naggar AK. Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance. Am J Pathol. 2013 Jun; 182(6):2048-57. PMID: 23583282; PMCID: PMC3668022.
      Citations: 9     Fields:    Translation:Humans
    153. Bell D, El-Naggar AK. Molecular heterogeneity in mucoepidermoid carcinoma: conceptual and practical implications. Head Neck Pathol. 2013 Mar; 7(1):23-7. PMID: 23459841; PMCID: PMC3597160.
      Citations: 19     Fields:    Translation:Humans
    154. Arduino PG, Bagan J, El-Naggar AK, Carrozzo M. Urban legends series: oral leukoplakia. Oral Dis. 2013 Oct; 19(7):642-59. PMID: 23379968.
      Citations: 24     Fields:    Translation:Humans
    155. Guan X, Sturgis EM, Song X, Liu Z, El-Naggar AK, Wei Q, Li G. Pre-microRNA variants predict HPV16-positive tumors and survival in patients with squamous cell carcinoma of the oropharynx. Cancer Lett. 2013 Apr 28; 330(2):233-40. PMID: 23219900; PMCID: PMC3563870.
      Citations: 15     Fields:    Translation:HumansCells
    156. Gillenwater AM, Frank SJ, Fatani H, El-Naggar AK. Primary intestinal-like adenocarcinoma of major salivary glands: 2 instances of previously undocumented phenotype. Head Neck. 2013 Aug; 35(8):E234-6. PMID: 23108630.
      Citations: 5     Fields:    Translation:Humans
    157. Ivanov SV, Panaccione A, Brown B, Guo Y, Moskaluk CA, Wick MJ, Brown JL, Ivanova AV, Issaeva N, El-Naggar AK, Yarbrough WG. TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior. Oncogene. 2013 Aug 08; 32(32):3698-710. PMID: 23027130.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    158. Sandulache VC, Ow TJ, Daram SP, Hamilton J, Skinner H, Bell D, Rosenthal DI, Beadle BM, Ang KK, Kies MS, Johnson FM, El-Naggar AK, Myers JN. Residual nodal disease in patients with advanced-stage oropharyngeal squamous cell carcinoma treated with definitive radiation therapy and posttreatment neck dissection: Association with locoregional recurrence, distant metastasis, and decreased survival. Head Neck. 2013 Oct; 35(10):1454-60. PMID: 23018868.
      Citations: 2     Fields:    Translation:Humans
    159. El-Naggar AK. Salivary gland cancer: assessing elusive behavior. Expert Rev Endocrinol Metab. 2012 Sep; 7(5):479-481. PMID: 30780890.
      Citations:    Fields:    
    160. Adelstein DJ, Koyfman SA, El-Naggar AK, Hanna EY. Biology and management of salivary gland cancers. Semin Radiat Oncol. 2012 Jul; 22(3):245-53. PMID: 22687949.
      Citations: 46     Fields:    Translation:Humans
    161. Jackson JG, Pant V, Li Q, Chang LL, Garza D, Tavana O, Yang P, Manshouri T, Li Y, El-Naggar AK, Lozano G, Quint?s-Cardama A. p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. Cancer Cell. 2012 Jun 12; 21(6):793-806. PMID: 22698404; PMCID: PMC3376352.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    162. Thariat J, Ang KK, Allen PK, Ahamad A, Williams MD, Myers JN, El-Naggar AK, Ginsberg LE, Rosenthal DI, Glisson BS, Morrison WH, Weber RS, Garden AS. Prediction of neck dissection requirement after definitive radiotherapy for head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2012 Mar 01; 82(3):e367-74. PMID: 22284033; PMCID: PMC4124997.
      Citations: 11     Fields:    Translation:Humans
    163. Sano D, Gule MK, Rosenthal DI, Bell D, Yates J, El-Naggar AK, Myers JN. Early postoperative epidermal growth factor receptor inhibition: safety and effectiveness in inhibiting microscopic residual of oral squamous cell carcinoma in vivo. Head Neck. 2013 Mar; 35(3):321-8. PMID: 22367702; PMCID: PMC3836367.
      Citations: 3     Fields:    Translation:HumansAnimals
    164. Bell D, N Myers J, Rao PH, El-Naggar AK. t(3;8) as the sole chromosomal abnormality in a myoepithelial carcinoma ex pleomorphic adenoma: a putative progression event. Head Neck. 2013 Jun; 35(6):E181-3. PMID: 22287457.
      Citations: 2     Fields:    Translation:HumansCells
    165. Galer C, Santillan AA, Chelius D, Huh W, El-Naggar A, Hanna E, Weber RS, Kupferman ME. Minor salivary gland malignancies in the pediatric population. Head Neck. 2012 Nov; 34(11):1648-51. PMID: 22267165.
      Citations: 1     Fields:    Translation:Humans
    166. Lewis CM, Glisson BS, Feng L, Wan F, Tang X, Wistuba II, El-Naggar AK, Rosenthal DI, Chambers MS, Lustig RA, Weber RS. A phase II study of gefitinib for aggressive cutaneous squamous cell carcinoma of the head and neck. Clin Cancer Res. 2012 Mar 01; 18(5):1435-46. PMID: 22261807; PMCID: PMC6167936.
      Citations: 43     Fields:    Translation:HumansCTClinical Trials
    167. Santarpia L, Lippman SM, El-Naggar AK. Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy. Expert Opin Ther Targets. 2012 Jan; 16(1):103-19. PMID: 22239440; PMCID: PMC3457779.
      Citations: 306     Fields:    Translation:HumansAnimalsCells
    168. Burch-Smith R, Ordonez NG, Ginsberg LE, Ater JL, El Naggar AK. Oral extragonadal yolk sac tumor in a patient with Aicardi syndrome: putative origin and differential diagnosis. Hum Pathol. 2012 Jun; 43(6):939-42. PMID: 22225777.
      Citations:    Fields:    Translation:Humans
    169. Li N, Xu L, Zhao H, El-Naggar AK, Sturgis EM. A comparison of the demographics, clinical features, and survival of patients with adenoid cystic carcinoma of major and minor salivary glands versus less common sites within the Surveillance, Epidemiology, and End Results registry. Cancer. 2012 Aug 15; 118(16):3945-53. PMID: 22179977; PMCID: PMC3412946.
      Citations: 37     Fields:    Translation:Humans
    170. McHugh CH, Roberts DB, El-Naggar AK, Hanna EY, Garden AS, Kies MS, Weber RS, Kupferman ME. Prognostic factors in mucoepidermoid carcinoma of the salivary glands. Cancer. 2012 Aug 15; 118(16):3928-36. PMID: 22180391.
      Citations: 49     Fields:    Translation:Humans
    171. El-Naggar AK, Westra WH. p16 expression as a surrogate marker for HPV-related oropharyngeal carcinoma: a guide for interpretative relevance and consistency. Head Neck. 2012 Apr; 34(4):459-61. PMID: 22180304.
      Citations: 86     Fields:    Translation:HumansCells
    172. Sen B, Peng S, Woods DM, Wistuba I, Bell D, El-Naggar AK, Lai SY, Johnson FM. STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma. Clin Cancer Res. 2012 Jan 01; 18(1):127-39. PMID: 22090359; PMCID: PMC3251692.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    173. Berinstein NL, Wolf GT, Naylor PH, Baltzer L, Egan JE, Brandwein HJ, Whiteside TL, Goldstein LC, El-Naggar A, Badoual C, Fridman WH, White JM, Hadden JW. Increased lymphocyte infiltration in patients with head and neck cancer treated with the IRX-2 immunotherapy regimen. Cancer Immunol Immunother. 2012 Jun; 61(6):771-82. PMID: 22057678; PMCID: PMC5300054.
      Citations: 20     Fields:    Translation:HumansCellsCTClinical Trials
    174. Bhayani MK, Yener M, El-Naggar A, Garden A, Hanna EY, Weber RS, Kupferman ME. Prognosis and risk factors for early-stage adenoid cystic carcinoma of the major salivary glands. Cancer. 2012 Jun 01; 118(11):2872-8. PMID: 22020577.
      Citations: 33     Fields:    Translation:Humans
    175. Kies MS, Boatright DH, Li G, Blumenschein G, El-Naggar AK, Brandon Gunn G, Lewin JS, Steinhaus GD, Sturgis EM. Phase II trial of induction chemotherapy followed by surgery for squamous cell carcinoma of the oral tongue in young adults. Head Neck. 2012 Sep; 34(9):1255-62. PMID: 22009800; PMCID: PMC3893095.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    176. Suh YA, Post SM, Elizondo-Fraire AC, Maccio DR, Jackson JG, El-Naggar AK, Van Pelt C, Terzian T, Lozano G. Multiple stress signals activate mutant p53 in vivo. Cancer Res. 2011 Dec 01; 71(23):7168-75. PMID: 21983037; PMCID: PMC3320147.
      Citations: 61     Fields:    Translation:AnimalsCells
    177. Shin DH, Min HY, El-Naggar AK, Lippman SM, Glisson B, Lee HY. Akt/mTOR counteract the antitumor activities of cixutumumab, an anti-insulin-like growth factor I receptor monoclonal antibody. Mol Cancer Ther. 2011 Dec; 10(12):2437-48. PMID: 21980128; PMCID: PMC3237768.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    178. Mitani Y, Rao PH, Futreal PA, Roberts DB, Stephens PJ, Zhao YJ, Zhang L, Mitani M, Weber RS, Lippman SM, Caulin C, El-Naggar AK. Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome. Clin Cancer Res. 2011 Nov 15; 17(22):7003-14. PMID: 21976542; PMCID: PMC3225955.
      Citations: 44     Fields:    Translation:HumansCells
    179. Bell D, Roberts D, Karpowicz M, Hanna EY, Weber RS, El-Naggar AK. Clinical significance of Myb protein and downstream target genes in salivary adenoid cystic carcinoma. Cancer Biol Ther. 2011 Oct 01; 12(7):569-73. PMID: 21785271; PMCID: PMC3218383.
      Citations: 27     Fields:    Translation:Humans
    180. Acin S, Li Z, Mejia O, Roop DR, El-Naggar AK, Caulin C. Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras. J Pathol. 2011 Dec; 225(4):479-89. PMID: 21952947; PMCID: PMC4302750.
      Citations: 26     Fields:    Translation:AnimalsCells
    181. Papaemmanuil E, Cazzola M, Boultwood J, Malcovati L, Vyas P, Bowen D, Pellagatti A, Wainscoat JS, Hellstrom-Lindberg E, Gambacorti-Passerini C, Godfrey AL, Rapado I, Cvejic A, Rance R, McGee C, Ellis P, Mudie LJ, Stephens PJ, McLaren S, Massie CE, Tarpey PS, Varela I, Nik-Zainal S, Davies HR, Shlien A, Jones D, Raine K, Hinton J, Butler AP, Teague JW, Baxter EJ, Score J, Galli A, Della Porta MG, Travaglino E, Groves M, Tauro S, Munshi NC, Anderson KC, El-Naggar A, Fischer A, Mustonen V, Warren AJ, Cross NC, Green AR, Futreal PA, Stratton MR, Campbell PJ, Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium. Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. N Engl J Med. 2011 Oct 13; 365(15):1384-95. PMID: 21995386; PMCID: PMC3322589.
      Citations: 507     Fields:    Translation:HumansCells
    182. Jerjes WK, Upile T, Wong BJ, Betz CS, Sterenborg HJ, Witjes MJ, Berg K, van Veen R, Biel MA, El-Naggar AK, Mosse CA, Olivo M, Richards-Kortum R, Robinson DJ, Rosen J, Yodh AG, Kendall C, Ilgner JF, Amelink A, Bagnato V, Barr H, Bolotine L, Bigio I, Chen Z, Choo-Smith LP, D'Cruz AK, Gillenwater A, Leunig A, MacRobert AJ, McKenzie G, Sandison A, Soo KC, Stepp H, Stone N, Svanberg K, Tan IB, Wilson BC, Wolfsen H, Hopper C. The future of medical diagnostics: review paper. Head Neck Oncol. 2011 Aug 23; 3:38. PMID: 21861912; PMCID: PMC3180646.
      Citations: 5     Fields:    Translation:Humans
    183. Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN, Trevi?o L. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science. 2011 Aug 26; 333(6046):1154-7. PMID: 21798897; PMCID: PMC3162986.
      Citations: 840     Fields:    Translation:HumansAnimalsCells
    184. Bell D, Bell A, Roberts D, Weber RS, El-Naggar AK. Developmental transcription factor EN1--a novel biomarker in human salivary gland adenoid cystic carcinoma. Cancer. 2012 Mar 01; 118(5):1288-92. PMID: 21800291; PMCID: PMC3208084.
      Citations: 17     Fields:    Translation:Humans
    185. Xu L, Li G, Wei Q, El-Naggar AK, Sturgis EM. Family history of cancer and risk of sporadic differentiated thyroid carcinoma. Cancer. 2012 Mar 01; 118(5):1228-35. PMID: 21800288; PMCID: PMC3208119.
      Citations: 13     Fields:    Translation:Humans
    186. Likhacheva A, Rosenthal DI, Hanna E, Kupferman M, Demonte F, El-Naggar AK. Sinonasal neuroendocrine carcinoma: impact of differentiation status on response and outcome. Head Neck Oncol. 2011 Jul 27; 3:32. PMID: 21794118; PMCID: PMC3154852.
      Citations: 14     Fields:    Translation:Humans
    187. Zevallos JP, Jain KS, Roberts D, El-Naggar A, Hanna EY, Kupferman ME. Sinonasal malignancies in children: a 10-year, single-institutional review. Laryngoscope. 2011 Sep; 121(9):2001-3. PMID: 21739433.
      Citations: 3     Fields:    Translation:Humans
    188. Gomez-Rivera F, El-Naggar AK, Guha-Thakurta N, Kupferman ME. Rheumatoid arthritis mimicking metastatic squamous cell carcinoma. Head Neck Oncol. 2011 May 14; 3:26. PMID: 21569598; PMCID: PMC3118955.
      Citations: 1     Fields:    Translation:Humans
    189. Mitani Y, Li J, Weber RS, Lippman SL, Flores ER, Caulin C, El-Naggar AK. Expression and regulation of the ?N and TAp63 isoforms in salivary gland tumorigenesis clinical and experimental findings. Am J Pathol. 2011 Jul; 179(1):391-9. PMID: 21703418; PMCID: PMC3123859.
      Citations: 8     Fields:    Translation:HumansCells
    190. Williams MD, Zhang L, Elliott DD, Perrier ND, Lozano G, Clayman GL, El-Naggar AK. Differential gene expression profiling of aggressive and nonaggressive follicular carcinomas. Hum Pathol. 2011 Sep; 42(9):1213-20. PMID: 21420716; PMCID: PMC3156288.
      Citations: 11     Fields:    Translation:Humans
    191. Karpowicz MK, Shalmon B, Molberg KH, El-Naggar AK. Melanoma in a carcinoma ex pleomorphic adenoma of the parotid gland: a case report and putative histogenesis. Hum Pathol. 2011 Sep; 42(9):1355-8. PMID: 21411120.
      Citations: 3     Fields:    Translation:Humans
    192. Jiffar T, Yilmaz T, Lee J, Hanna E, El-Naggar A, Yu D, Myers JN, Kupferman ME. KiSS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma. Oncogene. 2011 Jul 14; 30(28):3163-73. PMID: 21383688; PMCID: PMC3136629.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    193. Wang Y, Suh YA, Fuller MY, Jackson JG, Xiong S, Terzian T, Bankson JA, El-Naggar AK, Lozano G, Quint?s-Cardama A. Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation. J Clin Invest. 2011 Mar; 121(3):893-904. PMID: 21285512; PMCID: PMC3049366.
      Citations: 75     Fields:    Translation:AnimalsCells
    194. Upile T, Jerjes WK, Sterenborg HJ, Wong BJ, El-Naggar AK, Ilgner JF, Sandison A, Witjes MJ, Biel MA, van Veen R, Hamdoon Z, Gillenwater A, Mosse CA, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Barr H, Chen Z, Berg K, D'Cruz AK, Sudhoff H, Stone N, Kendall C, Fisher S, MacRobert AJ, Leunig A, Olivo M, Richards-Kortum R, Soo KC, Bagnato V, Choo-Smith LP, Svanberg K, Tan IB, Wilson BC, Wolfsen H, Bigio I, Yodh AG, Hopper C. At the frontiers of surgery: review. Head Neck Oncol. 2011 Feb 09; 3(1):7. PMID: 21306627; PMCID: PMC3048561.
      Citations: 3     Fields:    Translation:Humans
    195. Hong DS, Cabanillas ME, Wheler J, Naing A, Tsimberidou AM, Ye L, Busaidy NL, Waguespack SG, Hernandez M, El Naggar AK, El Naggar AK, Bidyasar S, Wright J, Sherman SI, Kurzrock R. Inhibition of the Ras/Raf/MEK/ERK and RET kinase pathways with the combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in medullary and differentiated thyroid malignancies. J Clin Endocrinol Metab. 2011 Apr; 96(4):997-1005. PMID: 21289252; PMCID: PMC3070247.
      Citations: 40     Fields:    Translation:HumansCellsCTClinical Trials
    196. Frederick MJ, VanMeter AJ, Gadhikar MA, Henderson YC, Yao H, Pickering CC, Williams MD, El-Naggar AK, Sandulache V, Tarco E, Myers JN, Clayman GL, Liotta LA, Petricoin EF, Calvert VS, Fodale V, Wang J, Weber RS. Phosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samples. Am J Pathol. 2011 Feb; 178(2):548-71. PMID: 21281788; PMCID: PMC3070553.
      Citations: 16     Fields:    Translation:HumansCells
    197. Galer CE, Corey CL, Wang Z, Younes MN, Gomez-Rivera F, Jasser SA, Ludwig DL, El-Naggar AK, Weber RS, Myers JN. Dual inhibition of epidermal growth factor receptor and insulin-like growth factor receptor I: reduction of angiogenesis and tumor growth in cutaneous squamous cell carcinoma. Head Neck. 2011 Feb; 33(2):189-98. PMID: 20848439; PMCID: PMC3010504.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    198. Saintigny P, Zhang L, Fan YH, El-Naggar AK, Papadimitrakopoulou VA, Feng L, Lee JJ, Kim ES, Ki Hong W, Mao L. Gene expression profiling predicts the development of oral cancer. Cancer Prev Res (Phila). 2011 Feb; 4(2):218-29. PMID: 21292635; PMCID: PMC3074595.
      Citations: 53     Fields:    Translation:Humans
    199. Devaney KO, Ferlito A, Rinaldo A, El-Naggar AK, Barnes L. Verrucous carcinoma (carcinoma cuniculatum) of the head and neck: what do we know now that we did not know a decade ago? Eur Arch Otorhinolaryngol. 2011 Apr; 268(4):477-80. PMID: 21286737.
      Citations: 6     Fields:    Translation:Humans
    200. Ryan JT, El-Naggar AK, Huh W, Hanna EY, Weber RS, Kupferman ME. Primacy of surgery in the management of mucoepidermoid carcinoma in children. Head Neck. 2011 Dec; 33(12):1769-73. PMID: 21284057.
      Citations: 2     Fields:    Translation:Humans
    201. Bell A, Bell D, Weber RS, El-Naggar AK. CpG island methylation profiling in human salivary gland adenoid cystic carcinoma. Cancer. 2011 Jul 01; 117(13):2898-909. PMID: 21692051; PMCID: PMC3123690.
      Citations: 60     Fields:    Translation:HumansCells
    202. Sethi K, Sarkar S, Das S, Rajput S, Mazumder A, Roy B, Patra S, Mohanty B, El-Naggar AK, Mandal M. Expressions of CK-19, NF-kappaB, E-cadherin, beta-catenin and EGFR as diagnostic and prognostic markers by immunohistochemical analysis in thyroid carcinoma. J Exp Ther Oncol. 2011; 9(3):187-99. PMID: 22070050.
      Citations: 9     Fields:    Translation:Humans
    203. Bell D, Holsinger CF, El-Naggar AK. CRTC1/MAML2 fusion transcript in central mucoepidermoid carcinoma of mandible--diagnostic and histogenetic implications. Ann Diagn Pathol. 2010 Dec; 14(6):396-401. PMID: 21074686.
      Citations: 5     Fields:    Translation:Humans
    204. Lewis CM, Hessel AC, Roberts DB, Guo YZ, Holsinger FC, Ginsberg LE, El-Naggar AK, Weber RS. Prereferral head and neck cancer treatment: compliance with national comprehensive cancer network treatment guidelines. Arch Otolaryngol Head Neck Surg. 2010 Dec; 136(12):1205-11. PMID: 21173369; PMCID: PMC5841162.
      Citations: 25     Fields:    Translation:Humans
    205. Brooks HD, Glisson BS, Bekele BN, Johnson FM, Ginsberg LE, El-Naggar A, Culotta KS, Takebe N, Wright J, Tran HT, Papadimitrakopoulou VA. Phase 2 study of dasatinib in the treatment of head and neck squamous cell carcinoma. Cancer. 2011 May 15; 117(10):2112-9. PMID: 21523723; PMCID: PMC3117018.
      Citations: 52     Fields:    Translation:HumansCTClinical Trials
    206. Diegel CR, Cho KR, El-Naggar AK, Williams BO, Lindvall C. Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma. Cancer Res. 2010 Nov 15; 70(22):9143-52. PMID: 21062985.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    207. Roblyer D, Kurachi C, Stepanek V, Schwarz RA, Williams MD, El-Naggar AK, Lee JJ, Gillenwater AM, Richards-Kortum R. Comparison of multispectral wide-field optical imaging modalities to maximize image contrast for objective discrimination of oral neoplasia. J Biomed Opt. 2010 Nov-Dec; 15(6):066017. PMID: 21198191; PMCID: PMC3013151.
      Citations: 9     Fields:    Translation:Humans
    208. Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ER. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature. 2010 Oct 21; 467(7318):986-90. PMID: 20962848; PMCID: PMC3055799.
      Citations: 251     Fields:    Translation:HumansAnimalsCells
    209. Liu Z, Liu D, Bojdani E, El-Naggar AK, Vasko V, Xing M. IQGAP1 plays an important role in the invasiveness of thyroid cancer. Clin Cancer Res. 2010 Dec 15; 16(24):6009-18. PMID: 20959410; PMCID: PMC3005072.
      Citations: 26     Fields:    Translation:HumansCells
    210. Liu Z, Li G, Wei S, Niu J, El-Naggar AK, Sturgis EM, Wei Q. Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck. Cancer. 2010 Oct 15; 116(20):4753-60. PMID: 20549817; PMCID: PMC3030480.
      Citations: 78     Fields:    Translation:Humans
    211. Niu J, Huang YJ, Wei S, Liu Z, Wang LE, Chang S, Chamberlain RM, El-Naggar AK, Sturgis EM, Wei Q. Association between a functional polymorphism (-1195T>C) in the IGFBP5 promoter and head and neck cancer risk. Head Neck. 2011 May; 33(5):650-60. PMID: 20949447; PMCID: PMC3023825.
      Citations: 4     Fields:    Translation:HumansCells
    212. Lo EJ, Bell D, Woo JS, Li G, Hanna EY, El-Naggar AK, Sturgis EM. Human papillomavirus and WHO type I nasopharyngeal carcinoma. Laryngoscope. 2010 Oct; 120(10):1990-7. PMID: 20824783; PMCID: PMC4212520.
      Citations: 20     Fields:    Translation:HumansCells
    213. Vadhan-Raj S, Trent J, Patel S, Zhou X, Johnson MM, Araujo D, Ludwig JA, O'Roark S, Gillenwater AM, Bueso-Ramos C, El-Naggar AK, Benjamin RS. Single-dose palifermin prevents severe oral mucositis during multicycle chemotherapy in patients with cancer: a randomized trial. Ann Intern Med. 2010 Sep 21; 153(6):358-67. PMID: 20855800.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    214. Bell D, Roberts D, Kies M, Rao P, Weber RS, El-Naggar AK. Cell type-dependent biomarker expression in adenoid cystic carcinoma: biologic and therapeutic implications. Cancer. 2010 Dec 15; 116(24):5749-56. PMID: 20824717; PMCID: PMC2998592.
      Citations: 18     Fields:    Translation:Humans
    215. Mitani Y, Li J, Rao PH, Zhao YJ, Bell D, Lippman SM, Weber RS, Caulin C, El-Naggar AK. Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: Incidence, variability, and clinicopathologic significance. Clin Cancer Res. 2010 Oct 01; 16(19):4722-31. PMID: 20702610; PMCID: PMC5862426.
      Citations: 84     Fields:    Translation:Humans
    216. Hessel AC, Moreno MA, Hanna EY, Roberts DB, Lewin JS, El-Naggar AK, Rosenthal DI, Weber RS. Compliance with quality assurance measures in patients treated for early oral tongue cancer. Cancer. 2010 Jul 15; 116(14):3408-16. PMID: 20564059; PMCID: PMC6088384.
      Citations: 13     Fields:    Translation:Humans
    217. Taoudi Benchekroun M, Saintigny P, Thomas SM, El-Naggar AK, Papadimitrakopoulou V, Ren H, Lang W, Fan YH, Huang J, Feng L, Lee JJ, Kim ES, Hong WK, Johnson FM, Grandis JR, Mao L. Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer. Cancer Prev Res (Phila). 2010 Jul; 3(7):800-9. PMID: 20570883; PMCID: PMC2900459.
      Citations: 44     Fields:    Translation:Humans
    218. Wei S, Liu Z, Zhao H, Niu J, Wang LE, El-Naggar AK, Sturgis EM, Wei Q. A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck. Cancer. 2010 Jun 15; 116(12):2984-92. PMID: 20336794; PMCID: PMC2891145.
      Citations: 10     Fields:    Translation:Humans
    219. Santarpia L, Myers JN, Sherman SI, Trimarchi F, Clayman GL, El-Naggar AK. Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma. Cancer. 2010 Jun 15; 116(12):2974-83. PMID: 20564403.
      Citations: 33     Fields:    Translation:HumansCells
    220. Byers LA, Holsinger FC, Kies MS, William WN, El-Naggar AK, Lee JJ, Hu J, Lopez A, Tran HT, Yan S, Du Z, Ang KK, Glisson BS, Raso MG, Wistuba II, Myers JN, Hong WK, Papadimitrakopoulou V, Lippman SM, Heymach JV. Serum signature of hypoxia-regulated factors is associated with progression after induction therapy in head and neck squamous cell cancer. Mol Cancer Ther. 2010 Jun; 9(6):1755-63. PMID: 20530716; PMCID: PMC2913168.
      Citations: 24     Fields:    Translation:HumansCells
    221. Moskaluk CA, Frierson HF, El-Naggar AK, Futreal PA. C-kit gene mutations in adenoid cystic carcinoma are rare. Mod Pathol. 2010 Jun; 23(6):905-6; author reply 906-7. PMID: 20514080.
      Citations: 6     Fields:    Translation:Humans
    222. Moreno MA, Roberts DB, Kupferman ME, DeMonte F, El-Naggar AK, Williams M, Rosenthal DS, Hanna EY. Mucosal melanoma of the nose and paranasal sinuses, a contemporary experience from the M. D. Anderson Cancer Center. Cancer. 2010 May 01; 116(9):2215-23. PMID: 20198705.
      Citations: 50     Fields:    Translation:Humans
    223. Williams MD, Roberts DB, Kies MS, Mao L, Weber RS, El-Naggar AK. Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance. Clin Cancer Res. 2010 Apr 15; 16(8):2266-74. PMID: 20371674; PMCID: PMC4152860.
      Citations: 50     Fields:    Translation:HumansCells
    224. Bedard N, Pierce M, El-Nagger A, Anandasabapathy S, Gillenwater A, Richards-Kortum R. Emerging roles for multimodal optical imaging in early cancer detection: a global challenge. Technol Cancer Res Treat. 2010 Apr; 9(2):211-7. PMID: 20218743; PMCID: PMC2906814.
      Citations: 11     Fields:    Translation:Humans
    225. Frank SJ, Rosenthal DI, Petsuksiri J, Ang KK, Morrison WH, Weber RS, Glisson BS, Chao KS, Schwartz DL, Chronowski GM, El-Naggar AK, Garden AS. Intensity-modulated radiotherapy for cervical node squamous cell carcinoma metastases from unknown head-and-neck primary site: M. D. Anderson Cancer Center outcomes and patterns of failure. Int J Radiat Oncol Biol Phys. 2010 Nov 15; 78(4):1005-10. PMID: 20207504.
      Citations: 21     Fields:    Translation:Humans
    226. Civantos FJ, Zitsch RP, Schuller DE, Agrawal A, Smith RB, Nason R, Petruzelli G, Gourin CG, Wong RJ, Ferris RL, El Naggar A, Ridge JA, Paniello RC, Owzar K, McCall L, Chepeha DB, Yarbrough WG, Myers JN. Sentinel lymph node biopsy accurately stages the regional lymph nodes for T1-T2 oral squamous cell carcinomas: results of a prospective multi-institutional trial. J Clin Oncol. 2010 Mar 10; 28(8):1395-400. PMID: 20142602; PMCID: PMC2834497.
      Citations: 73     Fields:    Translation:Humans
    227. Li C, Lu J, Liu Z, Wang LE, Zhao H, El-Naggar AK, Sturgis EM, Wei Q. The six-nucleotide deletion/insertion variant in the CASP8 promoter region is inversely associated with risk of squamous cell carcinoma of the head and neck. Cancer Prev Res (Phila). 2010 Feb; 3(2):246-53. PMID: 20086182; PMCID: PMC2818282.
      Citations: 15     Fields:    Translation:HumansCells
    228. Kupferman ME, Jiffar T, El-Naggar A, Yilmaz T, Zhou G, Xie T, Feng L, Wang J, Holsinger FC, Yu D, Myers JN. TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma. Oncogene. 2010 Apr 08; 29(14):2047-59. PMID: 20101235; PMCID: PMC3138334.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    229. Wang LE, Hu Z, Sturgis EM, Spitz MR, Strom SS, Amos CI, Guo Z, Qiao Y, Gillenwater AM, Myers JN, Clayman GL, Weber RS, El-Naggar AK, Mao L, Lippman SM, Hong WK, Wei Q. Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck cancer but not tumor characteristics. Clin Cancer Res. 2010 Jan 15; 16(2):764-74. PMID: 20068090; PMCID: PMC2848391.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    230. Lo EJ, Bell D, Woo J, Li G, Hanna EY, El-Naggar AK, Sturgis EM. Human papillomavirus & WHO type I nasopharyngeal carcinoma. Laryngoscope. 2010; 120 Suppl 4:S185. PMID: 21225783.
      Citations: 5     Fields:    Translation:HumansCells
    231. Anzick SL, Chen WD, Park Y, Meltzer P, Bell D, El-Naggar AK, Kaye FJ. Unfavorable prognosis of CRTC1-MAML2 positive mucoepidermoid tumors with CDKN2A deletions. Genes Chromosomes Cancer. 2010 Jan; 49(1):59-69. PMID: 19827123; PMCID: PMC2783528.
      Citations: 21     Fields:    Translation:Humans
    232. Mithani SK, Shao C, Tan M, Smith IM, Califano JA, El-Naggar AK, Ha PK. Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. PLoS One. 2009 Dec 30; 4(12):e8493. PMID: 20041111; PMCID: PMC2795173.
      Citations: 10     Fields:    Translation:HumansCells
    233. Nash JW, Hessel AC, Vigneswaran N, El-Naggar AK. Collagenous myofibroblastic tumor of the mandible: case report of a unique locally aggressive neoplasm. Head Neck Pathol. 2010 Mar; 4(1):44-8. PMID: 20237988; PMCID: PMC2825531.
      Citations: 4     Fields:    Translation:Humans
    234. El-Naggar AK, Kaye FJ, Shirazi Y, Gutkind JS, Forastiere AA. Meeting report--the NIDCR 2(nd) Salivary Gland Tumor Meeting, November 2008. Head Neck. 2009 Dec; 31(12):1542-3. PMID: 19890918.
      Citations: 1     Fields:    Translation:Humans
    235. Kies MS, Holsinger FC, Lee JJ, William WN, Glisson BS, Lin HY, Lewin JS, Ginsberg LE, Gillaspy KA, Massarelli E, Byers L, Lippman SM, Hong WK, El-Naggar AK, Garden AS, Papadimitrakopoulou V. Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial. J Clin Oncol. 2010 Jan 01; 28(1):8-14. PMID: 19917840; PMCID: PMC2799235.
      Citations: 65     Fields:    Translation:HumansCellsCTClinical Trials
    236. Hong DS, Sebti SM, Newman RA, Blaskovich MA, Ye L, Gagel RF, Moulder S, Wheler JJ, Naing A, Tannir NM, Ng CS, Sherman SI, El Naggar AK, Khan R, Trent J, Wright JJ, Kurzrock R. Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies. Clin Cancer Res. 2009 Nov 15; 15(22):7061-8. PMID: 19903778; PMCID: PMC2784003.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    237. Tsao AS, Liu D, Martin J, Tang XM, Lee JJ, El-Naggar AK, Wistuba I, Culotta KS, Mao L, Gillenwater A, Sagesaka YM, Hong WK, Papadimitrakopoulou V. Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions. Cancer Prev Res (Phila). 2009 Nov; 2(11):931-41. PMID: 19892663; PMCID: PMC4243312.
      Citations: 82     Fields:    Translation:HumansCTClinical Trials
    238. Saintigny P, El-Naggar AK, Papadimitrakopoulou V, Ren H, Fan YH, Feng L, Lee JJ, Kim ES, Hong WK, Lippman SM, Mao L. DeltaNp63 overexpression, alone and in combination with other biomarkers, predicts the development of oral cancer in patients with leukoplakia. Clin Cancer Res. 2009 Oct 01; 15(19):6284-91. PMID: 19773378; PMCID: PMC2756317.
      Citations: 25     Fields:    Translation:HumansCells
    239. Saba NF, Choi M, Muller S, Shin HJ, Tighiouart M, Papadimitrakopoulou VA, El-Naggar AK, Khuri FR, Chen ZG, Shin DM. Role of cyclooxygenase-2 in tumor progression and survival of head and neck squamous cell carcinoma. Cancer Prev Res (Phila). 2009 Sep; 2(9):823-9. PMID: 19737986; PMCID: PMC2910364.
      Citations: 21     Fields:    Translation:Humans
    240. Clayman GL, Shellenberger TD, Ginsberg LE, Edeiken BS, El-Naggar AK, Sellin RV, Waguespack SG, Roberts DB, Mishra A, Sherman SI. Approach and safety of comprehensive central compartment dissection in patients with recurrent papillary thyroid carcinoma. Head Neck. 2009 Sep; 31(9):1152-63. PMID: 19360746.
      Citations: 20     Fields:    Translation:Humans
    241. Bell D, Kupferman ME, Williams MD, Rashid A, El-Naggar AK. Primary colonic-type adenocarcinoma of the base of the tongue: a previously unreported phenotype. Hum Pathol. 2009 Dec; 40(12):1798-802. PMID: 19695679; PMCID: PMC3296116.
      Citations: 13     Fields:    Translation:Humans
    242. Lu J, Hu Z, Wei S, Wang LE, Liu Z, El-Naggar AK, Sturgis EM, Wei Q. A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity. Carcinogenesis. 2009 Oct; 30(10):1717-21. PMID: 19625347; PMCID: PMC2757547.
      Citations: 31     Fields:    Translation:HumansCells
    243. Upile T, Jerjes W, Sterenborg HJ, El-Naggar AK, Sandison A, Witjes MJ, Biel MA, Bigio I, Wong BJ, Gillenwater A, MacRobert AJ, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Mosse CA, Barr H, Chen Z, Berg K, D'Cruz AK, Stone N, Kendall C, Fisher S, Leunig A, Olivo M, Richards-Kortum R, Soo KC, Bagnato V, Choo-Smith LP, Svanberg K, Tan IB, Wilson BC, Wolfsen H, Yodh AG, Hopper C. Head & neck optical diagnostics: vision of the future of surgery. Head Neck Oncol. 2009 Jul 13; 1:25. PMID: 19594907; PMCID: PMC2720388.
      Citations: 16     Fields:    Translation:Humans
    244. Nitin N, Rosbach KJ, El-Naggar A, Williams M, Gillenwater A, Richards-Kortum RR. Optical molecular imaging of epidermal growth factor receptor expression to improve detection of oral neoplasia. Neoplasia. 2009 Jun; 11(6):542-51. PMID: 19484143; PMCID: PMC2685443.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    245. Nitin N, Carlson AL, Muldoon T, El-Naggar AK, Gillenwater A, Richards-Kortum R. Molecular imaging of glucose uptake in oral neoplasia following topical application of fluorescently labeled deoxy-glucose. Int J Cancer. 2009 Jun 01; 124(11):2634-42. PMID: 19173294; PMCID: PMC2700039.
      Citations: 37     Fields:    Translation:HumansCells
    246. Lott ST, Chen N, Chandler DS, Yang Q, Wang L, Rodriguez M, Xie H, Balasenthil S, Buchholz TA, Sahin AA, Chaung K, Zhang B, Olufemi SE, Chen J, Adams H, Band V, El-Naggar AK, Frazier ML, Keyomarsi K, Hunt KK, Sen S, Haffty B, Hewitt SM, Krahe R, Killary AM. DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer. PLoS Med. 2009 May 26; 6(5):e1000068. PMID: 19536326; PMCID: PMC2673042.
      Citations: 23     Fields:    Translation:HumansCells
    247. Mazumdar A, Henderson YC, El-Naggar AK, Sen S, Clayman GL. Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma. Head Neck. 2009 May; 31(5):625-34. PMID: 19107951; PMCID: PMC2668723.
      Citations: 33     Fields:    Translation:HumansCells
    248. Ramdas L, Giri U, Ashorn CL, Coombes KR, El-Naggar A, Ang KK, Story MD. miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue. Head Neck. 2009 May; 31(5):642-54. PMID: 19260130; PMCID: PMC2668741.
      Citations: 66     Fields:    Translation:HumansCells
    249. Roblyer D, Kurachi C, Stepanek V, Williams MD, El-Naggar AK, Lee JJ, Gillenwater AM, Richards-Kortum R. Objective detection and delineation of oral neoplasia using autofluorescence imaging. Cancer Prev Res (Phila). 2009 May; 2(5):423-31. PMID: 19401530; PMCID: PMC2719708.
      Citations: 59     Fields:    Translation:HumansPHPublic Health
    250. Schwarz RA, Gao W, Redden Weber C, Kurachi C, Lee JJ, El-Naggar AK, Richards-Kortum R, Gillenwater AM. Noninvasive evaluation of oral lesions using depth-sensitive optical spectroscopy. Cancer. 2009 Apr 15; 115(8):1669-79. PMID: 19170229; PMCID: PMC2728679.
      Citations: 43     Fields:    Translation:Humans
    251. Holsinger FC, Kies MS, Diaz EM, Gillenwater AM, Lewin JS, Ginsberg LE, Glisson BS, Garden AS, Ark N, Lin HY, Lee JJ, El-Naggar AK, Ki Hong W, Shin DM, Khuri FR. Durable long-term remission with chemotherapy alone for stage II to IV laryngeal cancer. J Clin Oncol. 2009 Apr 20; 27(12):1976-82. PMID: 19289628; PMCID: PMC2738635.
      Citations: 13     Fields:    Translation:Humans
    252. Batsakis JG, Ayala A, El Naggar AK. In memoriam: Mario A. Luna, MD. Adv Anat Pathol. 2009 Mar; 16(2):133-4. PMID: 19685607.
      Citations:    Fields:    
    253. Santarpia L, Sherman SI, Marabotti A, Clayman GL, El-Naggar AK. Detection and molecular characterization of a novel BRAF activated domain mutation in follicular variant of papillary thyroid carcinoma. Hum Pathol. 2009 Jun; 40(6):827-33. PMID: 19200582.
      Citations: 10     Fields:    Translation:Humans
    254. Chakravarty G, Santillan AA, Galer C, Adams HP, El-Naggar AK, Jasser SA, Mohsin S, Mondal D, Clayman GL, Myers JN. Phosphorylated insulin like growth factor-I receptor expression and its clinico-pathological significance in histologic subtypes of human thyroid cancer. Exp Biol Med (Maywood). 2009 Apr; 234(4):372-86. PMID: 19176870.
      Citations: 7     Fields:    Translation:HumansCells
    255. Henderson YC, Shellenberger TD, Williams MD, El-Naggar AK, Fredrick MJ, Cieply KM, Clayman GL. High rate of BRAF and RET/PTC dual mutations associated with recurrent papillary thyroid carcinoma. Clin Cancer Res. 2009 Jan 15; 15(2):485-91. PMID: 19147753; PMCID: PMC3038608.
      Citations: 50     Fields:    Translation:HumansCells
    256. Cordes B, Williams MD, Tirado Y, Bell D, Rosenthal DI, Al-Dhahri SF, Hanna EY, El-Naggar AK. Molecular and phenotypic analysis of poorly differentiated sinonasal neoplasms: an integrated approach for early diagnosis and classification. Hum Pathol. 2009 Mar; 40(3):283-92. PMID: 19150107; PMCID: PMC4573623.
      Citations: 14     Fields:    Translation:Humans
    257. El-Naggar AK, Hopper C, Upile T, Jerjes W. Head & Neck Oncology: purpose, scope and goals-charting the future. Head Neck Oncol. 2009 Jan 12; 1:1. PMID: 19284679; PMCID: PMC2640479.
      Citations:    Fields:    Translation:Humans
    258. Papadimitrakopoulou V, Izzo JG, Liu DD, Myers J, Ceron TL, Lewin J, William WN, Atwell A, Lee JJ, Gillenwater A, El-Naggar A, Wu X, Lippman SM, Hittelman WN, Hong WK. Cyclin D1 and cancer development in laryngeal premalignancy patients. Cancer Prev Res (Phila). 2009 Jan; 2(1):14-21. PMID: 19139013; PMCID: PMC4243520.
      Citations: 12     Fields:    Translation:Humans
    259. Gelbard A, Kupferman ME, Jasser SA, Chen W, El-Naggar AK, Myers JN, Hanna EY. An orthotopic murine model of sinonasal malignancy. Clin Cancer Res. 2008 Nov 15; 14(22):7348-57. PMID: 19010850; PMCID: PMC5428892.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    260. Pavlova I, Weber CR, Schwarz RA, Williams M, El-Naggar A, Gillenwater A, Richards-Kortum R. Monte Carlo model to describe depth selective fluorescence spectra of epithelial tissue: applications for diagnosis of oral precancer. J Biomed Opt. 2008 Nov-Dec; 13(6):064012. PMID: 19123659; PMCID: PMC2615394.
      Citations: 13     Fields:    
    261. Ye L, Santarpia L, Cote GJ, El-Naggar AK, Gagel RF. High resolution array-comparative genomic hybridization profiling reveals deoxyribonucleic acid copy number alterations associated with medullary thyroid carcinoma. J Clin Endocrinol Metab. 2008 Nov; 93(11):4367-72. PMID: 18765511; PMCID: PMC2729231.
      Citations: 17     Fields:    Translation:HumansCells
    262. Zhang N, Ge G, Meyer R, Sethi S, Basu D, Pradhan S, Zhao YJ, Li XN, Cai WW, El-Naggar AK, Baladandayuthapani V, Kittrell FS, Rao PH, Medina D, Pati D. Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):13033-8. PMID: 18728194; PMCID: PMC2529090.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    263. Choi S, Sano D, Cheung M, Zhao M, Jasser SA, Ryan AJ, Mao L, Chen WT, El-Naggar AK, Myers JN. Vandetanib inhibits growth of adenoid cystic carcinoma in an orthotopic nude mouse model. Clin Cancer Res. 2008 Aug 15; 14(16):5081-9. PMID: 18698025.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    264. Rao PH, Roberts D, Zhao YJ, Bell D, Harris CP, Weber RS, El-Naggar AK. Deletion of 1p32-p36 is the most frequent genetic change and poor prognostic marker in adenoid cystic carcinoma of the salivary glands. Clin Cancer Res. 2008 Aug 15; 14(16):5181-7. PMID: 18698036.
      Citations: 29     Fields:    Translation:HumansCells
    265. Chen X, Sturgis EM, El-Naggar AK, Wei Q, Li G. Combined effects of the p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms on the risk of HPV16-associated oral cancer in never-smokers. Carcinogenesis. 2008 Nov; 29(11):2120-5. PMID: 18701437; PMCID: PMC2577141.
      Citations: 20     Fields:    Translation:HumansCells
    266. Chambers MS, Tomsett KL, Artopoulou II, Garden AS, El-Naggar AK, Martin JW, Keene HJ. Salivary flow rates measured during radiation therapy in head and neck cancer patients: a pilot study assessing salivary sediment formation. J Prosthet Dent. 2008 Aug; 100(2):142-6. PMID: 18672129.
      Citations: 4     Fields:    Translation:Humans
    267. Santarpia L, El-Naggar AK, Sherman SI, Hymes SR, Gagel RF, Shaw S, Sarlis NJ. Four patients with cutaneous metastases from medullary thyroid cancer. Thyroid. 2008 Aug; 18(8):901-5. PMID: 18651821.
      Citations: 3     Fields:    Translation:Humans
    268. Chattopadhyay C, El-Naggar AK, Williams MD, Clayman GL. Small molecule c-MET inhibitor PHA665752: effect on cell growth and motility in papillary thyroid carcinoma. Head Neck. 2008 Aug; 30(8):991-1000. PMID: 18327775.
      Citations: 16     Fields:    Translation:HumansCells
    269. Zhai X, Zhao H, Liu Z, Wang LE, El-Naggar AK, Sturgis EM, Wei Q. Functional variants of the NEIL1 and NEIL2 genes and risk and progression of squamous cell carcinoma of the oral cavity and oropharynx. Clin Cancer Res. 2008 Jul 01; 14(13):4345-52. PMID: 18594018; PMCID: PMC3025759.
      Citations: 17     Fields:    Translation:Humans
    270. Thariat J, Ahamad A, El-Naggar AK, Williams MD, Holsinger FC, Glisson BS, Allen PK, Morrison WH, Weber RS, Ang KK, Garden AS. Outcomes after radiotherapy for basaloid squamous cell carcinoma of the head and neck: a case-control study. Cancer. 2008 Jun 15; 112(12):2698-709. PMID: 18429002.
      Citations: 9     Fields:    Translation:Humans
    271. Smith SL, Hessel AC, Luna MA, Malpica A, Rosenthal DI, El-Naggar AK. Sinonasal teratocarcinosarcoma of the head and neck: a report of 10 patients treated at a single institution and comparison with reported series. Arch Otolaryngol Head Neck Surg. 2008 Jun; 134(6):592-5. PMID: 18559724.
      Citations: 19     Fields:    Translation:Humans
    272. Barboza JA, Iwakuma T, Terzian T, El-Naggar AK, Lozano G. Mdm2 and Mdm4 loss regulates distinct p53 activities. Mol Cancer Res. 2008 Jun; 6(6):947-54. PMID: 18567799; PMCID: PMC2699947.
      Citations: 46     Fields:    Translation:AnimalsCells
    273. Liu Z, Hou P, Ji M, Guan H, Studeman K, Jensen K, Vasko V, El-Naggar AK, Xing M. Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers. J Clin Endocrinol Metab. 2008 Aug; 93(8):3106-16. PMID: 18492751.
      Citations: 167     Fields:    Translation:HumansCells
    274. Yildirim G, Gillenwater AM, Ordonez NG, Garden AS, El-Naggar AK. Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. Head Neck. 2008 May; 30(5):675-9. PMID: 17972308.
      Citations: 1     Fields:    Translation:HumansCells
    275. Lee ES, Issa JP, Roberts DB, Williams MD, Weber RS, Kies MS, El-Naggar AK. Quantitative promoter hypermethylation analysis of cancer-related genes in salivary gland carcinomas: comparison with methylation-specific PCR technique and clinical significance. Clin Cancer Res. 2008 May 01; 14(9):2664-72. PMID: 18451230.
      Citations: 21     Fields:    Translation:HumansCells
    276. Mandal M, Myers JN, Lippman SM, Johnson FM, Williams MD, Rayala S, Ohshiro K, Rosenthal DI, Weber RS, Gallick GE, El-Naggar AK. Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features. Cancer. 2008 May 01; 112(9):2088-100. PMID: 18327819.
      Citations: 72     Fields:    Translation:HumansCells
    277. Hong D, Ye L, Gagel R, Chintala L, El Naggar AK, Wright J, Kurzrock R. Medullary thyroid cancer: targeting the RET kinase pathway with sorafenib/tipifarnib. Mol Cancer Ther. 2008 May; 7(5):1001-6. PMID: 18445656.
      Citations: 15     Fields:    Translation:HumansCells
    278. Pavlova I, Williams M, El-Naggar A, Richards-Kortum R, Gillenwater A. Understanding the biological basis of autofluorescence imaging for oral cancer detection: high-resolution fluorescence microscopy in viable tissue. Clin Cancer Res. 2008 Apr 15; 14(8):2396-404. PMID: 18413830; PMCID: PMC2773159.
      Citations: 82     Fields:    Translation:Humans
    279. Maitland KC, Gillenwater AM, Williams MD, El-Naggar AK, Descour MR, Richards-Kortum RR. In vivo imaging of oral neoplasia using a miniaturized fiber optic confocal reflectance microscope. Oral Oncol. 2008 Nov; 44(11):1059-66. PMID: 18396445; PMCID: PMC2673342.
      Citations: 40     Fields:    Translation:Humans
    280. Mishra A, El-Naggar AK, DeMonte F, Hanna EY. Endodermal sinus tumor of the paranasal sinuses. Head Neck. 2008 Apr; 30(4):539-43. PMID: 17902152.
      Citations: 4     Fields:    Translation:Humans
    281. Bell D, Luna MA, Weber RS, Kaye FJ, El-Naggar AK. CRTC1/MAML2 fusion transcript in Warthin's tumor and mucoepidermoid carcinoma: evidence for a common genetic association. Genes Chromosomes Cancer. 2008 Apr; 47(4):309-14. PMID: 18181164.
      Citations: 20     Fields:    Translation:Humans
    282. Papadimitrakopoulou VA, William WN, Dannenberg AJ, Lippman SM, Lee JJ, Ondrey FG, Peterson DE, Feng L, Atwell A, El-Naggar AK, Nathan CO, Helman JI, Du B, Yueh B, Boyle JO. Pilot randomized phase II study of celecoxib in oral premalignant lesions. Clin Cancer Res. 2008 Apr 01; 14(7):2095-101. PMID: 18381950.
      Citations: 40     Fields:    Translation:HumansCTClinical Trials
    283. Roblyer D, Richards-Kortum R, Sokolov K, El-Naggar AK, Williams MD, Kurachi C, Gillenwater AM. Multispectral optical imaging device for in vivo detection of oral neoplasia. J Biomed Opt. 2008 Mar-Apr; 13(2):024019. PMID: 18465982; PMCID: PMC3970814.
      Citations: 70     Fields:    Translation:Humans
    284. Zhou G, Xie TX, Zhao M, Jasser SA, Younes MN, Sano D, Lin J, Kupferman ME, Santillan AA, Patel V, Gutkind JS, Ei-Naggar AK, Emberley ED, Watson PH, Matsuzawa SI, Reed JC, Myers JN. Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity. Oncogene. 2008 Jun 05; 27(25):3527-38. PMID: 18223693.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    285. Kawaguchi H, El-Naggar AK, Papadimitrakopoulou V, Ren H, Fan YH, Feng L, Lee JJ, Kim E, Hong WK, Lippman SM, Mao L. Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy. J Clin Oncol. 2008 Jan 20; 26(3):354-60. PMID: 18202409.
      Citations: 69     Fields:    Translation:HumansCells
    286. Lupinetti AD, Roberts DB, Williams MD, Kupferman ME, Rosenthal DI, Demonte F, El-Naggar A, Weber RS, Hanna EY. Sinonasal adenoid cystic carcinoma: the M. D. Anderson Cancer Center experience. Cancer. 2007 Dec 15; 110(12):2726-31. PMID: 17960615.
      Citations: 34     Fields:    Translation:Humans
    287. Xiong P, Hu Z, Li C, Wang LE, El-Naggar AK, Sturgis EM, Wei Q. In vitro benzo[a]pyrene diol epoxide-induced DNA damage and chromosomal aberrations in primary lymphocytes, smoking, and risk of squamous cell carcinoma of the head and neck. Int J Cancer. 2007 Dec 15; 121(12):2735-40. PMID: 17724733.
      Citations: 7     Fields:    Translation:HumansCells
    288. Armistead PM, Salganick J, Roh JS, Steinert DM, Patel S, Munsell M, El-Naggar AK, Benjamin RS, Zhang W, Trent JC. Expression of receptor tyrosine kinases and apoptotic molecules in rhabdomyosarcoma: correlation with overall survival in 105 patients. Cancer. 2007 Nov 15; 110(10):2293-303. PMID: 17896786.
      Citations: 30     Fields:    Translation:Humans
    289. Santarpia L, El-Naggar AK, Cote GJ, Myers JN, Sherman SI. Phosphatidylinositol 3-kinase/akt and ras/raf-mitogen-activated protein kinase pathway mutations in anaplastic thyroid cancer. J Clin Endocrinol Metab. 2008 Jan; 93(1):278-84. PMID: 17989125.
      Citations: 78     Fields:    Translation:HumansCells
    290. Williams MD, Roberts D, Blumenschein GR, Temam S, Kies MS, Rosenthal DI, Weber RS, El-Naggar AK. Differential expression of hormonal and growth factor receptors in salivary duct carcinomas: biologic significance and potential role in therapeutic stratification of patients. Am J Surg Pathol. 2007 Nov; 31(11):1645-52. PMID: 18059220.
      Citations: 65     Fields:    Translation:HumansCells
    291. Wang LE, Li C, Strom SS, Goldberg LH, Brewster A, Guo Z, Qiao Y, Clayman GL, Lee JJ, El-Naggar AK, Prieto VG, Duvic M, Lippman SM, Weber RS, Kripke ML, Wei Q. Repair capacity for UV light induced DNA damage associated with risk of nonmelanoma skin cancer and tumor progression. Clin Cancer Res. 2007 Nov 01; 13(21):6532-9. PMID: 17975167.
      Citations: 22     Fields:    Translation:HumansCells
    292. El-Naggar AK. Pathobiology of head and neck squamous tumorigenesis. Curr Cancer Drug Targets. 2007 Nov; 7(7):606-12. PMID: 18045065.
      Citations: 1     Fields:    Translation:Humans
    293. Ohshiro K, Rayala SK, El-Naggar AK, Kumar R. Delivery of cytoplasmic proteins to autophagosomes. Autophagy. 2008 Jan; 4(1):104-6. PMID: 18000392.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    294. Bell D, Zhao YJ, Rao PH, Weber RS, El-Naggar AK. Translocation t(6;14) as the sole chromosomal abnormality in adenoid cystic carcinoma of the base of tongue. Head Neck Pathol. 2007 Dec; 1(2):165-8. PMID: 20614269; PMCID: PMC2807514.
      Citations: 4     Fields:    Translation:HumansCells
    295. Naqvi J, Ordonez NG, Luna MA, Williams MD, Weber RS, El-Naggar AK. Epithelioid hemangioendothelioma of the head and neck: role of podoplanin in the differential diagnosis. Head Neck Pathol. 2008 Mar; 2(1):25-30. PMID: 20614338; PMCID: PMC2807604.
      Citations: 17     Fields:    Translation:Humans
    296. Elliott DD, Sherman SI, Busaidy NL, Williams MD, Santarpia L, Clayman GL, El-Naggar AK. Growth factor receptors expression in anaplastic thyroid carcinoma: potential markers for therapeutic stratification. Hum Pathol. 2008 Jan; 39(1):15-20. PMID: 17949783.
      Citations: 12     Fields:    Translation:HumansCells
    297. Carlson AL, Gillenwater AM, Williams MD, El-Naggar AK, Richards-Kortum RR. Confocal microscopy and molecular-specific optical contrast agents for the detection of oral neoplasia. Technol Cancer Res Treat. 2007 Oct; 6(5):361-74. PMID: 17877424; PMCID: PMC2772068.
      Citations: 3     Fields:    Translation:HumansCells
    298. Ohshiro K, Rayala SK, Kondo S, Gaur A, Vadlamudi RK, El-Naggar AK, Kumar R. Identifying the estrogen receptor coactivator PELP1 in autophagosomes. Cancer Res. 2007 Sep 01; 67(17):8164-71. PMID: 17804729.
      Citations: 17     Fields:    Translation:HumansCells
    299. Li C, Hu Z, Lu J, Liu Z, Wang LE, El-Naggar AK, Sturgis EM, Spitz MR, Wei Q. Genetic polymorphisms in DNA base-excision repair genes ADPRT, XRCC1, and APE1 and the risk of squamous cell carcinoma of the head and neck. Cancer. 2007 Aug 15; 110(4):867-75. PMID: 17614107.
      Citations: 37     Fields:    Translation:HumansCells
    300. Chen K, Hu Z, Wang LE, Sturgis EM, El-Naggar AK, Zhang W, Wei Q. Single-nucleotide polymorphisms at the TP53-binding or responsive promoter regions of BAX and BCL2 genes and risk of squamous cell carcinoma of the head and neck. Carcinogenesis. 2007 Sep; 28(9):2008-12. PMID: 17693666.
      Citations: 33     Fields:    Translation:HumansCells
    301. An J, Liu Z, Hu Z, Li G, Wang LE, Sturgis EM, El-Naggar AK, Spitz MR, Wei Q. Potentially functional single nucleotide polymorphisms in the core nucleotide excision repair genes and risk of squamous cell carcinoma of the head and neck. Cancer Epidemiol Biomarkers Prev. 2007 Aug; 16(8):1633-8. PMID: 17684138.
      Citations: 30     Fields:    Translation:HumansCells
    302. Valentin-Vega YA, Barboza JA, Chau GP, El-Naggar AK, Lozano G. High levels of the p53 inhibitor MDM4 in head and neck squamous carcinomas. Hum Pathol. 2007 Oct; 38(10):1553-62. PMID: 17651783; PMCID: PMC2699677.
      Citations: 38     Fields:    Translation:HumansCells
    303. Barnes CJ, Ohshiro K, Rayala SK, El-Naggar AK, Kumar R. Insulin-like growth factor receptor as a therapeutic target in head and neck cancer. Clin Cancer Res. 2007 Jul 15; 13(14):4291-9. PMID: 17634559.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    304. Chen K, Hu Z, Wang LE, Zhang W, El-Naggar AK, Sturgis EM, Wei Q. Polymorphic TP53BP1 and TP53 gene interactions associated with risk of squamous cell carcinoma of the head and neck. Clin Cancer Res. 2007 Jul 15; 13(14):4300-5. PMID: 17634560.
      Citations: 9     Fields:    Translation:Humans
    305. Tirado Y, Williams MD, Hanna EY, Kaye FJ, Batsakis JG, El-Naggar AK. CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: implications for histogenesis and biologic behavior. Genes Chromosomes Cancer. 2007 Jul; 46(7):708-15. PMID: 17437281.
      Citations: 54     Fields:    Translation:HumansCells
    306. Li D, Wang LE, Chang P, El-Naggar AK, Sturgis EM, Wei Q. In vitro benzo[a]pyrene diol epoxide-induced DNA adducts and risk of squamous cell carcinoma of head and neck. Cancer Res. 2007 Jun 15; 67(12):5628-34. PMID: 17575128.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    307. Koch JG, Gu X, Han Y, El-Naggar AK, Olson MV, Medina D, Jerry DJ, Blackburn AC, Peltz G, Amos CI, Lozano G. Mammary tumor modifiers in BALB/cJ mice heterozygous for p53. Mamm Genome. 2007 May; 18(5):300-9. PMID: 17557176.
      Citations: 25     Fields:    Translation:Animals
    308. Kim S, Yazici YD, Calzada G, Wang ZY, Younes MN, Jasser SA, El-Naggar AK, Myers JN. Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice. Mol Cancer Ther. 2007 Jun; 6(6):1785-92. PMID: 17575107.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    309. Kaszuba SM, Zafereo ME, Rosenthal DI, El-Naggar AK, Weber RS. Effect of initial treatment on disease outcome for patients with submandibular gland carcinoma. Arch Otolaryngol Head Neck Surg. 2007 Jun; 133(6):546-50. PMID: 17576904.
      Citations: 8     Fields:    Translation:Humans
    310. Temam S, Kawaguchi H, El-Naggar AK, Jelinek J, Tang H, Liu DD, Lang W, Issa JP, Lee JJ, Mao L. Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer. J Clin Oncol. 2007 Jun 01; 25(16):2164-70. PMID: 17538160.
      Citations: 139     Fields:    Translation:Humans
    311. Zheng S, El-Naggar AK, Kim ES, Kurie JM, Lozano G. A genetic mouse model for metastatic lung cancer with gender differences in survival. Oncogene. 2007 Oct 18; 26(48):6896-904. PMID: 17486075.
      Citations: 58     Fields:    Translation:Animals
    312. Schafer-Hales K, Iaconelli J, Snyder JP, Prussia A, Nettles JH, El-Naggar A, Khuri FR, Giannakakou P, Marcus AI. Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function. Mol Cancer Ther. 2007 Apr; 6(4):1317-28. PMID: 17431110.
      Citations: 36     Fields:    Translation:HumansCellsCTClinical Trials
    313. Ohshiro K, Rosenthal DI, Koomen JM, Streckfus CF, Chambers M, Kobayashi R, El-Naggar AK. Pre-analytic saliva processing affect proteomic results and biomarker screening of head and neck squamous carcinoma. Int J Oncol. 2007 Mar; 30(3):743-9. PMID: 17273777.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    314. Price ND, Trent J, El-Naggar AK, Cogdell D, Taylor E, Hunt KK, Pollock RE, Hood L, Shmulevich I, Zhang W. Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3414-9. PMID: 17360660; PMCID: PMC1805517.
      Citations: 76     Fields:    Translation:HumansCells
    315. Hou P, Liu D, Shan Y, Hu S, Studeman K, Condouris S, Wang Y, Trink A, El-Naggar AK, Tallini G, Vasko V, Xing M. Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer. Clin Cancer Res. 2007 Feb 15; 13(4):1161-70. PMID: 17317825.
      Citations: 165     Fields:    Translation:HumansCells
    316. Younes MN, Yigitbasi OG, Yazici YD, Jasser SA, Bucana CD, El-Naggar AK, Mills GB, Myers JN. Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg. 2007 Jan; 133(1):15-23. PMID: 17224516.
      Citations: 17     Fields:    Translation:HumansCells
    317. Williams MD, Chakravarti N, Kies MS, Maruya S, Myers JN, Haviland JC, Weber RS, Lotan R, El-Naggar AK. Implications of methylation patterns of cancer genes in salivary gland tumors. Clin Cancer Res. 2006 Dec 15; 12(24):7353-8. PMID: 17189407.
      Citations: 15     Fields:    Translation:HumansCells
    318. Barboza JA, Liu G, Ju Z, El-Naggar AK, Lozano G. p21 delays tumor onset by preservation of chromosomal stability. Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52):19842-7. PMID: 17170138; PMCID: PMC1702317.
      Citations: 54     Fields:    Translation:AnimalsCells
    319. Younes MN, Park YW, Yazici YD, Gu M, Santillan AA, Nong X, Kim S, Jasser SA, El-Naggar AK, Myers JN. Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model. Mol Cancer Ther. 2006 Nov; 5(11):2696-705. PMID: 17121916.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    320. Williams MD, Hanna EY, El-Naggar AK. Anaplastic ameloblastic fibrosarcoma arising from recurrent ameloblastic fibroma: restricted molecular abnormalities of certain genes to the malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jul; 104(1):72-5. PMID: 17577546.
      Citations: 12     Fields:    Translation:Humans
    321. Ohshiro K, Rayala SK, Williams MD, Kumar R, El-Naggar AK. Biological role of estrogen receptor beta in salivary gland adenocarcinoma cells. Clin Cancer Res. 2006 Oct 15; 12(20 Pt 1):5994-9. PMID: 17062671.
      Citations: 9     Fields:    Translation:HumansCells
    322. Zhang Z, Wang LE, Sturgis EM, El-Naggar AK, Hong WK, Amos CI, Spitz MR, Wei Q. Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck. Clin Cancer Res. 2006 Sep 15; 12(18):5596-602. PMID: 17000697.
      Citations: 29     Fields:    Translation:Humans
    323. Chung CH, Parker JS, Ely K, Carter J, Yi Y, Murphy BA, Ang KK, El-Naggar AK, Zanation AM, Cmelak AJ, Levy S, Slebos RJ, Yarbrough WG. Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma. Cancer Res. 2006 Aug 15; 66(16):8210-8. PMID: 16912200.
      Citations: 107     Fields:    Translation:HumansCells
    324. Yuan P, Temam S, El-Naggar A, Zhou X, Liu DD, Lee JJ, Mao L. Overexpression of podoplanin in oral cancer and its association with poor clinical outcome. Cancer. 2006 Aug 01; 107(3):563-9. PMID: 16804930.
      Citations: 106     Fields:    Translation:HumansCells
    325. Wang Z, Chakravarty G, Kim S, Yazici YD, Younes MN, Jasser SA, Santillan AA, Bucana CD, El-Naggar AK, Myers JN. Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma. Clin Cancer Res. 2006 Aug 01; 12(15):4755-65. PMID: 16899627.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    326. Hsu ER, Gillenwater AM, Hasan MQ, Williams MD, El-Naggar AK, Richards-Kortum RR. Real-time detection of epidermal growth factor receptor expression in fresh oral cavity biopsies using a molecular-specific contrast agent. Int J Cancer. 2006 Jun 15; 118(12):3062-71. PMID: 16395711.
      Citations: 4     Fields:    Translation:Humans
    327. Younes MN, Yazici YD, Kim S, Jasser SA, El-Naggar AK, Myers JN. Dual epidermal growth factor receptor and vascular endothelial growth factor receptor inhibition with NVP-AEE788 for the treatment of aggressive follicular thyroid cancer. Clin Cancer Res. 2006 Jun 01; 12(11 Pt 1):3425-34. PMID: 16740767.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    328. Lippman SM, Lee JJ, Martin JW, El-Naggar AK, Xu X, Shin DM, Thomas M, Mao L, Fritsche HA, Zhou X, Papadimitrakopoulou V, Khuri FR, Tran H, Clayman GL, Hittelman WN, Hong WK, Lotan R. Fenretinide activity in retinoid-resistant oral leukoplakia. Clin Cancer Res. 2006 May 15; 12(10):3109-14. PMID: 16707609.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    329. Nykter M, Hunt KK, Pollock RE, El-Naggar AK, Taylor E, Shmulevich I, Yli-Harja O, Zhang W. Unsupervised analysis uncovers changes in histopathologic diagnosis in supervised genomic studies. Technol Cancer Res Treat. 2006 Apr; 5(2):177-82. PMID: 16551137.
      Citations: 1     Fields:    Translation:Humans
    330. Yom SS, Rosenthal DI, El-Naggar AK, Kies MS, Hessel AC. Merkel cell carcinoma of the tongue and head and neck oral mucosal sites. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jun; 101(6):761-8. PMID: 16731397.
      Citations: 11     Fields:    Translation:Humans
    331. El-Naggar AK. Clear cell hidradenoma of the skin--a third tumor type with a t(11;19)-associated TORC1-MAML2 gene fusion: Genes Chromosomes Cancer. 2005;43:202-205. Adv Anat Pathol. 2006 Mar; 13(2):80-2. PMID: 16670462.
      Citations: 2     Fields:    Translation:Humans
    332. Mandal M, Younes M, Swan EA, Jasser SA, Doan D, Yigitbasi O, McMurphey A, Ludwick J, El-Naggar AK, Bucana C, Mills GB, Myers JN. The Akt inhibitor KP372-1 inhibits proliferation and induces apoptosis and anoikis in squamous cell carcinoma of the head and neck. Oral Oncol. 2006 Apr; 42(4):430-9. PMID: 16442835; PMCID: PMC1414640.
      Citations: 26     Fields:    Translation:HumansCells
    333. Oh SH, Kim WY, Kim JH, Younes MN, El-Naggar AK, Myers JN, Kies M, Cohen P, Khuri F, Hong WK, Lee HY. Identification of insulin-like growth factor binding protein-3 as a farnesyl transferase inhibitor SCH66336-induced negative regulator of angiogenesis in head and neck squamous cell carcinoma. Clin Cancer Res. 2006 Jan 15; 12(2):653-61. PMID: 16428512.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    334. Chakravarti N, El-Naggar AK, Lotan R, Anderson J, Diwan AH, Saadati HG, Diba R, Prieto VG, Esmaeli B. Expression of retinoid receptors in sebaceous cell carcinoma. J Cutan Pathol. 2006 Jan; 33(1):10-7. PMID: 16441406.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    335. Vielh P, Carton M, Padoy E, de Rycke Y, Klijanienko J, El-Naggar AK, Asselain B. S-phase fraction as an independent prognostic factor of long-term overall survival in patients with early-stage or locally advanced invasive breast carcinoma. Cancer. 2005 Dec 25; 105(6):476-82. PMID: 16116603.
      Citations: 3     Fields:    Translation:HumansCells
    336. Massarelli E, Liu DD, Lee JJ, El-Naggar AK, Lo Muzio L, Staibano S, De Placido S, Myers JN, Papadimitrakopoulou VA. Akt activation correlates with adverse outcome in tongue cancer. Cancer. 2005 Dec 01; 104(11):2430-6. PMID: 16245318.
      Citations: 42     Fields:    Translation:HumansCells
    337. Simon C, Goepfert H, Rosenthal DI, Roberts D, El-Naggar A, Old M, Diaz EM, Myers JN. Presence of malignant tumor cells in persistent neck disease after radiotherapy for advanced squamous cell carcinoma of the oropharynx is associated with poor survival. Eur Arch Otorhinolaryngol. 2006 Apr; 263(4):313-8. PMID: 16328403.
      Citations: 6     Fields:    Translation:Humans
    338. Giri U, Ashorn CL, Ramdas L, Stivers DN, Coombes K, El-Naggar AK, Ang KK, Story MD. Molecular signatures associated with clinical outcome in patients with high-risk head-and-neck squamous cell carcinoma treated by surgery and radiation. Int J Radiat Oncol Biol Phys. 2006 Mar 01; 64(3):670-7. PMID: 16289374.
      Citations: 13     Fields:    Translation:HumansCells
    339. Apisarnthanarax S, Elliott DD, El-Naggar AK, Asper JA, Blanco A, Ang KK, Garden AS, Morrison WH, Rosenthal D, Weber RS, Chao KS. Determining optimal clinical target volume margins in head-and-neck cancer based on microscopic extracapsular extension of metastatic neck nodes. Int J Radiat Oncol Biol Phys. 2006 Mar 01; 64(3):678-83. PMID: 16243444.
      Citations: 10     Fields:    Translation:Humans
    340. Schiff BA, Roberts DB, El-Naggar A, Garden AS, Myers JN. Selective vs modified radical neck dissection and postoperative radiotherapy vs observation in the treatment of squamous cell carcinoma of the oral tongue. Arch Otolaryngol Head Neck Surg. 2005 Oct; 131(10):874-8. PMID: 16230589.
      Citations: 13     Fields:    Translation:Humans
    341. Papadimitrakopoulou VA, Brown EN, Liu DD, El-Naggar AK, Jack Lee J, Hong WK, Lee HY. The prognostic role of loss of insulin-like growth factor-binding protein-3 expression in head and neck carcinogenesis. Cancer Lett. 2006 Jul 28; 239(1):136-43. PMID: 16181731.
      Citations: 20     Fields:    Translation:HumansCells
    342. Moore BA, Weber RS, Prieto V, El-Naggar A, Holsinger FC, Zhou X, Lee JJ, Lippman S, Clayman GL. Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck. Laryngoscope. 2005 Sep; 115(9):1561-7. PMID: 16148695.
      Citations: 49     Fields:    Translation:Humans
    343. Saffari B, Bernstein L, Hong DC, Sullivan-Halley J, Runnebaum IB, Grill HJ, Jones LA, El-Naggar A, Press MF. Association of p53 mutations and a codon 72 single nucleotide polymorphism with lower overall survival and responsiveness to adjuvant radiotherapy in endometrioid endometrial carcinomas. Int J Gynecol Cancer. 2005 Sep-Oct; 15(5):952-63. PMID: 16174251.
      Citations: 12     Fields:    Translation:HumansCells
    344. Li J, El-Naggar A, Mao L. Promoter methylation of p16INK4a, RASSF1A, and DAPK is frequent in salivary adenoid cystic carcinoma. Cancer. 2005 Aug 15; 104(4):771-6. PMID: 15959912.
      Citations: 21     Fields:    Translation:HumansCells
    345. Younes MN, Kim S, Yigitbasi OG, Mandal M, Jasser SA, Dakak Yazici Y, Schiff BA, El-Naggar A, Bekele BN, Mills GB, Myers JN. Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer. Mol Cancer Ther. 2005 Aug; 4(8):1146-56. PMID: 16093430.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    346. Yom SS, Machtay M, Biel MA, Sinard RJ, El-Naggar AK, Weber RS, Rosenthal DI. Survival impact of planned restaging and early surgical salvage following definitive chemoradiation for locally advanced squamous cell carcinomas of the oropharynx and hypopharynx. Am J Clin Oncol. 2005 Aug; 28(4):385-92. PMID: 16062081.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    347. Maruya S, Kies MS, Williams M, Myers JN, Weber RS, Batsakis JG, El-Naggar AK. Differential expression of p63 isotypes (DeltaN and TA) in salivary gland neoplasms: biological and diagnostic implications. Hum Pathol. 2005 Jul; 36(7):821-7. PMID: 16084953.
      Citations: 2     Fields:    Translation:Humans
    348. Gillenwater A, Lewin J, Roberts D, El-Naggar A. Moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the larynx: a clinically aggressive tumor. Laryngoscope. 2005 Jul; 115(7):1191-5. PMID: 15995505.
      Citations: 9     Fields:    Translation:Humans
    349. Chakravarti N, Saadati HG, El-Naggar AK, Lotan R, Diba RE, Esmaeli B. Retinoid receptor subtypes in sebaceous cell carcinoma of the eyelid. Ophthalmic Plast Reconstr Surg. 2005 Jul; 21(4):292-7. PMID: 16052143.
      Citations: 1     Fields:    Translation:Humans
    350. Vadlamudi RK, Balasenthil S, Sahin AA, Kies M, Weber RS, Kumar R, El-Naggar AK. Novel estrogen receptor coactivator PELP1/MNAR gene and ERbeta expression in salivary duct adenocarcinoma: potential therapeutic targets. Hum Pathol. 2005 Jun; 36(6):670-5. PMID: 16021574.
      Citations: 25     Fields:    Translation:Humans
    351. Backous DD, DeMonte F, El-Naggar A, Wolf P, Weber RS. Craniofacial resection for nonmelanoma skin cancer of the head and neck. Laryngoscope. 2005 Jun; 115(6):931-7. PMID: 15933497.
      Citations: 2     Fields:    Translation:Humans
    352. Mandal M, Kim S, Younes MN, Jasser SA, El-Naggar AK, Mills GB, Myers JN. The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells. Br J Cancer. 2005 May 23; 92(10):1899-905. PMID: 15870708; PMCID: PMC2361761.
      Citations: 27     Fields:    Translation:HumansCells
    353. Neumann AS, Lyons HJ, Shen H, Liu Z, Shi Q, Sturgis EM, Shete S, Spitz MR, El-Naggar A, Hong WK, Wei Q. Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Int J Cancer. 2005 May 20; 115(1):131-6. PMID: 15688408.
      Citations: 14     Fields:    Translation:Humans
    354. Jimenez C, Yang Y, Kim HW, Al-Sagier F, Berry DA, El-Naggar AK, Patel S, Vassilopoulou-Sellin R, Gagel RF. Primary hyperparathyroidism and osteosarcoma: examination of a large cohort identifies three cases of fibroblastic osteosarcoma. J Bone Miner Res. 2005 Sep; 20(9):1562-8. PMID: 16059628.
      Citations: 7     Fields:    Translation:Humans
    355. Marcus AI, Zhou J, O'Brate A, Hamel E, Wong J, Nivens M, El-Naggar A, Yao TP, Khuri FR, Giannakakou P. The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase. Cancer Res. 2005 May 01; 65(9):3883-93. PMID: 15867388; PMCID: PMC1861827.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    356. Maruya SI, Myers JN, Weber RS, Rosenthal DI, Lotan R, El-Naggar AK. ICAM-5 (telencephalin) gene expression in head and neck squamous carcinoma tumorigenesis and perineural invasion! Oral Oncol. 2005 Jul; 41(6):580-8. PMID: 15975520.
      Citations: 11     Fields:    Translation:HumansCells
    357. Jayakumar A, Kang Y, Henderson Y, Mitsudo K, Liu X, Briggs K, Wang M, Frederick MJ, El-Naggar AK, Clayman GL, Beb?k Z. Consequences of C-terminal domains and N-terminal signal peptide deletions on LEKTI secretion, stability, and subcellular distribution. Arch Biochem Biophys. 2005 Mar 01; 435(1):89-102. PMID: 15680911.
      Citations: 8     Fields:    Translation:HumansCells
    358. Massarelli E, Brown E, Tran NK, Liu DD, Izzo JG, Lee JJ, El-Naggar AK, Hong WK, Papadimitrakopoulou VA. Loss of E-cadherin and p27 expression is associated with head and neck squamous tumorigenesis. Cancer. 2005 Mar 01; 103(5):952-9. PMID: 15666322.
      Citations: 9     Fields:    Translation:Humans
    359. Yom SS, Rashid A, Rosenthal DI, Elliott DD, Hanna EY, Weber RS, El-Naggar AK. Genetic analysis of sinonasal adenocarcinoma phenotypes: distinct alterations of histogenetic significance. Mod Pathol. 2005 Mar; 18(3):315-9. PMID: 15492756.
      Citations: 19     Fields:    Translation:HumansCells
    360. Clayman GL, Lee JJ, Holsinger FC, Zhou X, Duvic M, El-Naggar AK, Prieto VG, Altamirano E, Tucker SL, Strom SS, Kripke ML, Lippman SM. Mortality risk from squamous cell skin cancer. J Clin Oncol. 2005 Feb 01; 23(4):759-65. PMID: 15681519.
      Citations: 67     Fields:    Translation:Humans
    361. Diaz EM, Johnigan RH, Pero C, El-Naggar AK, Roberts DB, Barker JL, DeMonte F. Olfactory neuroblastoma: the 22-year experience at one comprehensive cancer center. Head Neck. 2005 Feb; 27(2):138-49. PMID: 15654688.
      Citations: 50     Fields:    Translation:Humans
    362. Baker H, Patel V, Molinolo AA, Shillitoe EJ, Ensley JF, Yoo GH, Myers JN, El-Naggar AK, Gutkind JS, Hancock WS, Meneses-Garc?a A. Proteome-wide analysis of head and neck squamous cell carcinomas using laser-capture microdissection and tandem mass spectrometry. Oral Oncol. 2005 Feb; 41(2):183-99. PMID: 15695121.
      Citations: 24     Fields:    Translation:Humans
    363. Cohn ML, Elliott DD, El-Naggar AK. Metastatic acinic cell carcinoma in a neurofibroma mistaken for carcinosarcoma. Head Neck. 2005 Jan; 27(1):76-80. PMID: 15565563.
      Citations: 2     Fields:    Translation:Humans
    364. Lang GA, Iwakuma T, Suh YA, Liu G, Rao VA, Parant JM, Valentin-Vega YA, Terzian T, Caldwell LC, Strong LC, El-Naggar AK, Lozano G. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell. 2004 Dec 17; 119(6):861-72. PMID: 15607981.
      Citations: 508     Fields:    Translation:AnimalsCells
    365. Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN, Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN. Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer. Clin Cancer Res. 2004 Dec 15; 10(24):8594-602. PMID: 15623643.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    366. Rosenthal DI, Barker JL, El-Naggar AK, Glisson BS, Kies MS, Diaz EM, Clayman GL, Demonte F, Selek U, Morrison WH, Ang KK, Chao KS, Garden AS. Sinonasal malignancies with neuroendocrine differentiation: patterns of failure according to histologic phenotype. Cancer. 2004 Dec 01; 101(11):2567-73. PMID: 15517582.
      Citations: 44     Fields:    Translation:Humans
    367. Shellenberger TD, Wang M, Gujrati M, Jayakumar A, Strieter RM, Burdick MD, Ioannides CG, Efferson CL, El-Naggar AK, Roberts D, Clayman GL, Frederick MJ. BRAK/CXCL14 is a potent inhibitor of angiogenesis and a chemotactic factor for immature dendritic cells. Cancer Res. 2004 Nov 15; 64(22):8262-70. PMID: 15548693.
      Citations: 85     Fields:    Translation:HumansCells
    368. Clark AL, Gillenwater A, Alizadeh-Naderi R, El-Naggar AK, Richards-Kortum R. Detection and diagnosis of oral neoplasia with an optical coherence microscope. J Biomed Opt. 2004 Nov-Dec; 9(6):1271-80. PMID: 15568948; PMCID: PMC2773167.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    369. Curino A, Patel V, Nielsen BS, Iskander AJ, Ensley JF, Yoo GH, Holsinger FC, Myers JN, El-Nagaar A, Kellman RM, Shillitoe EJ, Molinolo AA, Gutkind JS, Bugge TH. Detection of plasminogen activators in oral cancer by laser capture microdissection combined with zymography. Oral Oncol. 2004 Nov; 40(10):1026-32. PMID: 15509494.
      Citations: 8     Fields:    Translation:Humans
    370. Wang L, Rodriguez M, Kim ES, Xu Y, Bekele N, El-Naggar AK, Hong WK, Mao L, Oh YW. A novel C/T polymorphism in the core promoter of human de novo cytosine DNA methyltransferase 3B6 is associated with prognosis in head and neck cancer. Int J Oncol. 2004 Oct; 25(4):993-9. PMID: 15375549.
      Citations: 15     Fields:    Translation:HumansCells
    371. Choi HR, Roberts DB, Johnigan RH, Sturgis EM, Rosenthal DI, Weber RS, Luna MA, Batsakis JG, El-Naggar AK. Molecular and clinicopathologic comparisons of head and neck squamous carcinoma variants: common and distinctive features of biological significance. Am J Surg Pathol. 2004 Oct; 28(10):1299-310. PMID: 15371945.
      Citations: 3     Fields:    Translation:HumansCells
    372. Ugolin N, Vielh P, Ory K, Elliott D, Clayman GL, El-Naggar AK, Chevillard S, Levalois C. Gene expression profiling of differentiated thyroid neoplasms: diagnostic and clinical implications. Clin Cancer Res. 2004 Oct 01; 10(19):6586-97. PMID: 15475448.
      Citations: 35     Fields:    Translation:Humans
    373. Tai SK, Lee JI, Ang KK, El-Naggar AK, Hassan KA, Liu D, Lee JJ, Ren H, Hong WK, Mao L. Loss of Fhit expression in head and neck squamous cell carcinoma and its potential clinical implication. Clin Cancer Res. 2004 Aug 15; 10(16):5554-7. PMID: 15328196.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    374. Barkan GA, El-Naggar AK. Primary synovial sarcoma of the parotid gland. Ann Diagn Pathol. 2004 Aug; 8(4):233-6. PMID: 15290676.
      Citations: 7     Fields:    Translation:Humans
    375. Cohn ML, Callender DL, El-Naggar AK. Sebaceous carcinoma ex-pleomorphic adenoma: a rare phenotypic occurrence. Ann Diagn Pathol. 2004 Aug; 8(4):224-6. PMID: 15290674.
      Citations: 4     Fields:    Translation:Humans
    376. Maruya S, Kim HW, Weber RS, Lee JJ, Kies M, Luna MA, Batsakis JG, El-Naggar AK. Gene expression screening of salivary gland neoplasms: molecular markers of potential histogenetic and clinical significance. J Mol Diagn. 2004 Aug; 6(3):180-90. PMID: 15269293; PMCID: PMC1867638.
      Citations: 17     Fields:    Translation:HumansCells
    377. Busaidy NL, Jimenez C, Habra MA, Schultz PN, El-Naggar AK, Clayman GL, Asper JA, Diaz EM, Evans DB, Gagel RF, Garden A, Hoff AO, Lee JE, Morrison WH, Rosenthal DI, Sherman SI, Sturgis EM, Waguespack SG, Weber RS, Wirfel K, Vassilopoulou-Sellin R. Parathyroid carcinoma: a 22-year experience. Head Neck. 2004 Aug; 26(8):716-26. PMID: 15287039.
      Citations: 69     Fields:    Translation:Humans
    378. Jimenez C, Habra MA, Huang SC, El-Naggar A, Shapiro SE, Evans DB, Cote G, Gagel RF. Pheochromocytoma and medullary thyroid carcinoma: a new genotype-phenotype correlation of the RET protooncogene 891 germline mutation. J Clin Endocrinol Metab. 2004 Aug; 89(8):4142-5. PMID: 15292360.
      Citations: 4     Fields:    Translation:Humans
    379. Jimenez C, Dang GT, Schultz PN, El-Naggar A, Shapiro S, Barnes EA, Evans DB, Vassilopoulou-Sellin R, Gagel RF, Cote GJ, Hoff AO. A novel point mutation of the RET protooncogene involving the second intracellular tyrosine kinase domain in a family with medullary thyroid carcinoma. J Clin Endocrinol Metab. 2004 Jul; 89(7):3521-6. PMID: 15240641.
      Citations: 12     Fields:    Translation:HumansCells
    380. Selek U, Garden AS, Morrison WH, El-Naggar AK, Rosenthal DI, Ang KK. Radiation therapy for early-stage carcinoma of the oropharynx. Int J Radiat Oncol Biol Phys. 2004 Jul 01; 59(3):743-51. PMID: 15183477.
      Citations: 14     Fields:    Translation:Humans
    381. Li G, Sturgis EM, Wang LE, Chamberlain RM, Spitz MR, El-Naggar AK, Hong WK, Wei Q. Association between the V109G polymorphism of the p27 gene and the risk and progression of oral squamous cell carcinoma. Clin Cancer Res. 2004 Jun 15; 10(12 Pt 1):3996-4002. PMID: 15217930.
      Citations: 18     Fields:    Translation:HumansCells
    382. Li G, Sturgis EM, Wang LE, Chamberlain RM, Amos CI, Spitz MR, El-Naggar AK, Hong WK, Wei Q. Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis. 2004 Oct; 25(10):1911-6. PMID: 15180941.
      Citations: 40     Fields:    Translation:Humans
    383. Zhang Z, Shi Q, Wang LE, Sturgis EM, Spitz MR, El-Naggar AK, Hong WK, Wei Q. No Association between hOGG1 Ser326Cys polymorphism and risk of squamous cell carcinoma of the head and neck. Cancer Epidemiol Biomarkers Prev. 2004 Jun; 13(6):1081-3. PMID: 15184269.
      Citations: 9     Fields:    Translation:Humans
    384. Fung KM, Diaz EM, El-Naggar AK, Luna MA. Malignant rhabdoid tumor arising from a pleomorphic adenoma. Ann Diagn Pathol. 2004 Jun; 8(3):156-61. PMID: 15185263.
      Citations: 2     Fields:    Translation:Humans
    385. Maruya S, Issa JP, Weber RS, Rosenthal DI, Haviland JC, Lotan R, El-Naggar AK. Differential methylation status of tumor-associated genes in head and neck squamous carcinoma: incidence and potential implications. Clin Cancer Res. 2004 Jun 01; 10(11):3825-30. PMID: 15173091.
      Citations: 49     Fields:    Translation:HumansCells
    386. Jayakumar A, Kang Y, Mitsudo K, Henderson Y, Frederick MJ, Wang M, El-Naggar AK, Marx UC, Briggs K, Clayman GL. Expression of LEKTI domains 6-9' in the baculovirus expression system: recombinant LEKTI domains 6-9' inhibit trypsin and subtilisin A. Protein Expr Purif. 2004 May; 35(1):93-101. PMID: 15039071.
      Citations: 11     Fields:    Translation:AnimalsCells
    387. Koh JS, Trent J, Chen L, El-Naggar A, Hunt K, Pollock R, Zhang W. Gastrointestinal stromal tumors: overview of pathologic features, molecular biology, and therapy with imatinib mesylate. Histol Histopathol. 2004 04; 19(2):565-74. PMID: 15024716.
      Citations: 12     Fields:    Translation:HumansCells
    388. Lippman SM, Lee JJ, Mao L, Kildal W, Sagen S, Bryne M, El-Naggar A, Evensen JF, Reith A, Sudb? J, Sudb? A, Risberg B. The influence of resection and aneuploidy on mortality in oral leukoplakia. N Engl J Med. 2004 Apr 01; 350(14):1405-13. PMID: 15070790.
      Citations: 12     Fields:    Translation:Humans
    389. Clayman GL, Gonzalez HE, El-Naggar A, Vassilopoulou-Sellin R. Parathyroid carcinoma: evaluation and interdisciplinary management. Cancer. 2004 Mar 01; 100(5):900-5. PMID: 14983483.
      Citations: 31     Fields:    Translation:Humans
    390. Svistun E, Alizadeh-Naderi R, El-Naggar A, Jacob R, Gillenwater A, Richards-Kortum R. Vision enhancement system for detection of oral cavity neoplasia based on autofluorescence. Head Neck. 2004 Mar; 26(3):205-15. PMID: 14999795.
      Citations: 28     Fields:    Translation:Humans
    391. Hsu ER, Anslyn EV, Dharmawardhane S, Alizadeh-Naderi R, Aaron JS, Sokolov KV, El-Naggar AK, Gillenwater AM, Richards-Kortum RR. A far-red fluorescent contrast agent to image epidermal growth factor receptor expression. Photochem Photobiol. 2004 Mar; 79(3):272-9. PMID: 15115300.
      Citations: 11     Fields:    Translation:HumansCells
    392. Glisson B, Colevas AD, Haddad R, Krane J, El-Naggar A, Kies M, Costello R, Summey C, Arquette M, Langer C, Amrein PC, Posner M. HER2 expression in salivary gland carcinomas: dependence on histological subtype. Clin Cancer Res. 2004 Feb 01; 10(3):944-6. PMID: 14871971.
      Citations: 59     Fields:    Translation:HumansCTClinical Trials
    393. Yang Z, Bagheri-Yarmand R, Wang RA, Adam L, Papadimitrakopoulou VV, Clayman GL, El-Naggar A, Lotan R, Barnes CJ, Hong WK, Kumar R. The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses c-Src and Pak1 pathways and invasiveness of human cancer cells. Clin Cancer Res. 2004 Jan 15; 10(2):658-67. PMID: 14760089.
      Citations: 33     Fields:    Translation:HumansCells
    394. Esmaeli B, Ahmadi MA, Youssef A, Diba R, Amato M, Myers JN, Kies M, El-Naggar A. Outcomes in patients with adenoid cystic carcinoma of the lacrimal gland. Ophthalmic Plast Reconstr Surg. 2004 Jan; 20(1):22-6. PMID: 14752305.
      Citations: 43     Fields:    Translation:Humans
    395. Moran CA, Suster S, El-Naggar A, Luna MA. Carcinomas arising in multilocular thymic cysts of the neck: a clinicopathological study of three cases. Histopathology. 2004 Jan; 44(1):64-8. PMID: 14717671.
      Citations: 7     Fields:    Translation:Humans
    396. El-Naggar AK, Vielh P. Solid tumor DNA content analysis. Methods Mol Biol. 2004; 263:355-70. PMID: 14976377.
      Citations:    Fields:    Translation:HumansCells
    397. El-Naggar AK. Concurrent flow cytometric analysis of DNA and RNA. Methods Mol Biol. 2004; 263:371-84. PMID: 14976378.
      Citations: 2     Fields:    Translation:HumansCells
    398. Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, El-Naggar AK, Multani A, Chang S, Lozano G. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nat Genet. 2004 Jan; 36(1):63-8. PMID: 14702042.
      Citations: 142     Fields:    Translation:Animals
    399. Coombes MM, Briggs KL, Bone JR, Clayman GL, El-Naggar AK, Dent SY. Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation. Oncogene. 2003 Dec 04; 22(55):8902-11. PMID: 14654786.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    400. Barker JL, Glisson BS, Garden AS, El-Naggar AK, Morrison WH, Ang KK, Chao KS, Clayman G, Rosenthal DI. Management of nonsinonasal neuroendocrine carcinomas of the head and neck. Cancer. 2003 Dec 01; 98(11):2322-8. PMID: 14635065.
      Citations: 25     Fields:    Translation:Humans
    401. Rudin CM, Cohen EE, Papadimitrakopoulou VA, Silverman S, Recant W, El-Naggar AK, Stenson K, Lippman SM, Hong WK, Vokes EE. An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia. J Clin Oncol. 2003 Dec 15; 21(24):4546-52. PMID: 14597742; PMCID: PMC4523388.
      Citations: 38     Fields:    Translation:HumansCellsCTClinical Trials
    402. Choi HR, Sturgis EM, Rashid A, DeMonte F, Luna MA, Batsakis JG, El-Naggar AK. Sinonasal adenocarcinoma: evidence for histogenetic divergence of the enteric and nonenteric phenotypes. Hum Pathol. 2003 Nov; 34(11):1101-7. PMID: 14652810.
      Citations: 18     Fields:    Translation:Humans
    403. Clark AL, Gillenwater AM, Collier TG, Alizadeh-Naderi R, El-Naggar AK, Richards-Kortum RR. Confocal microscopy for real-time detection of oral cavity neoplasia. Clin Cancer Res. 2003 Oct 15; 9(13):4714-21. PMID: 14581341.
      Citations: 30     Fields:    Translation:HumansCells
    404. Caudell JJ, Ballo MT, Zagars GK, Lewis VO, Weber KL, Lin PP, Marco RA, El-Naggar AK, Benjamin RS, Yasko AW. Radiotherapy in the management of giant cell tumor of bone. Int J Radiat Oncol Biol Phys. 2003 Sep 01; 57(1):158-65. PMID: 12909228.
      Citations: 55     Fields:    Translation:Humans
    405. Choi HR, Sturgis EM, Rosenthal DI, Luna MA, Batsakis JG, El-Naggar AK. Sarcomatoid carcinoma of the head and neck: molecular evidence for evolution and progression from conventional squamous cell carcinomas. Am J Surg Pathol. 2003 Sep; 27(9):1216-20. PMID: 12960805.
      Citations: 23     Fields:    Translation:HumansCells
    406. Greenberg JS, El Naggar AK, Mo V, Roberts D, Myers JN. Disparity in pathologic and clinical lymph node staging in oral tongue carcinoma. Implication for therapeutic decision making. Cancer. 2003 Aug 01; 98(3):508-15. PMID: 12879467.
      Citations: 54     Fields:    Translation:Humans
    407. Dahlstrom KR, Adler-Storthz K, Etzel CJ, Liu Z, Dillon L, El-Naggar AK, Spitz MR, Schiller JT, Wei Q, Sturgis EM. Human papillomavirus type 16 infection and squamous cell carcinoma of the head and neck in never-smokers: a matched pair analysis. Clin Cancer Res. 2003 Jul; 9(7):2620-6. PMID: 12855639.
      Citations: 53     Fields:    Translation:Humans
    408. MacGregor AR, Batsakis JG, El-Naggar AK. Myofibroblastoma of the larynx: a study of two cases. Head Neck. 2003 Jul; 25(7):606-11. PMID: 12808665.
      Citations: 4     Fields:    Translation:Humans
    409. Biddle DA, Evans HL, Kemp BL, El-Naggar AK, Harvell JD, White WL, Iskandar SS, Prieto VG. Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma. Am J Surg Pathol. 2003 May; 27(5):673-81. PMID: 12717252.
      Citations: 19     Fields:    Translation:HumansCells
    410. Mitsudo K, Jayakumar A, Henderson Y, Frederick MJ, Kang Y, Wang M, El-Naggar AK, Clayman GL. Inhibition of serine proteinases plasmin, trypsin, subtilisin A, cathepsin G, and elastase by LEKTI: a kinetic analysis. Biochemistry. 2003 Apr 08; 42(13):3874-81. PMID: 12667078.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    411. Sabloff B, Munden RF, Melhem AI, El-Naggar AK, Putnam JB. Radiologic-pathologic conferences of the University of Texas M. D. Anderson Cancer Center: Extraskeletal osteosarcoma of the pleura. AJR Am J Roentgenol. 2003 Apr; 180(4):972. PMID: 12646438.
      Citations: 9     Fields:    Translation:Humans
    412. Greenberg JS, Fowler R, Gomez J, Mo V, Roberts D, El Naggar AK, Myers JN. Extent of extracapsular spread: a critical prognosticator in oral tongue cancer. Cancer. 2003 Mar 15; 97(6):1464-70. PMID: 12627511.
      Citations: 75     Fields:    Translation:Humans
    413. Izzo JG, Papadimitrakopoulou VA, Liu DD, den Hollander PL, Babenko IM, Keck J, El-Naggar AK, Shin DM, Lee JJ, Hong WK, Hittelman WN. Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer. J Natl Cancer Inst. 2003 Feb 05; 95(3):198-205. PMID: 12569141.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    414. Choi HR, Tucker SA, Huang Z, Gillenwater AM, Luna MA, Batsakis JG, El-Naggar AK. Differential expressions of cyclin-dependent kinase inhibitors (p27 and p21) and their relation to p53 and Ki-67 in oral squamous tumorigenesis. Int J Oncol. 2003 Feb; 22(2):409-14. PMID: 12527941.
      Citations: 10     Fields:    Translation:HumansCells
    415. Tonon G, Modi S, Wu L, Kubo A, Coxon AB, Komiya T, O'Neil K, Stover K, El-Naggar A, Griffin JD, Kirsch IR, Kaye FJ. t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nat Genet. 2003 Feb; 33(2):208-13. PMID: 12539049.
      Citations: 166     Fields:    Translation:HumansAnimalsCells
    416. Jayakumar A, Kang Y, Frederick MJ, Pak SC, Henderson Y, Holton PR, Mitsudo K, Silverman GA, EL-Naggar AK, Clayman GL, Br?mme D. Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis. Arch Biochem Biophys. 2003 Jan 15; 409(2):367-74. PMID: 12504904.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    417. Bolshakov S, Walker CM, Strom SS, Selvan MS, Clayman GL, El-Naggar A, Lippman SM, Kripke ML, Ananthaswamy HN. p53 mutations in human aggressive and nonaggressive basal and squamous cell carcinomas. Clin Cancer Res. 2003 Jan; 9(1):228-34. PMID: 12538474.
      Citations: 38     Fields:    Translation:Humans
    418. Swisher SG, Roth JA, Komaki R, Gu J, Lee JJ, Hicks M, Ro JY, Hong WK, Merritt JA, Ahrar K, Atkinson NE, Correa AM, Dolormente M, Dreiling L, El-Naggar AK, Fossella F, Francisco R, Glisson B, Grammer S, Herbst R, Huaringa A, Kemp B, Khuri FR, Kurie JM, Liao Z, McDonnell TJ, Morice R, Morello F, Munden R, Papadimitrakopoulou V, Pisters KM, Putnam JB, Sarabia AJ, Shelton T, Stevens C, Shin DM, Smythe WR, Vaporciyan AA, Walsh GL, Yin M. Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy. Clin Cancer Res. 2003 Jan; 9(1):93-101. PMID: 12538456.
      Citations: 47     Fields:    Translation:HumansCellsCTClinical Trials
    419. Chang YS, Kong G, Sun S, Liu D, El-Naggar AK, Khuri FR, Hong WK, Lee HY, Gong K. Clinical significance of insulin-like growth factor-binding protein-3 expression in stage I non-small cell lung cancer. Clin Cancer Res. 2002 Dec; 8(12):3796-802. PMID: 12473592.
      Citations: 34     Fields:    Translation:HumansCells
    420. Papadimitrakopoulou VA, Liu DD, Mao L, Shin DM, El-Naggar A, Ibarguen H, Lee JJ, Hong WK, Hittelman WN. Biologic correlates of a biochemoprevention trial in advanced upper aerodigestive tract premalignant lesions. Cancer Epidemiol Biomarkers Prev. 2002 Dec; 11(12):1605-10. PMID: 12496051.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    421. El-Naggar AK, Kim HW, Clayman GL, Coombes MM, Le B, Lai S, Zhan F, Luna MA, Hong WK, Lee JJ. Differential expression profiling of head and neck squamous carcinoma: significance in their phenotypic and biological classification. Oncogene. 2002 Nov 21; 21(53):8206-19. PMID: 12444558.
      Citations: 16     Fields:    Translation:Humans
    422. Little DJ, Ballo MT, Zagars GK, Pisters PW, Patel SR, El-Naggar AK, Garden AS, Benjamin RS. Adult rhabdomyosarcoma: outcome following multimodality treatment. Cancer. 2002 Jul 15; 95(2):377-88. PMID: 12124838.
      Citations: 72     Fields:    Translation:Humans
    423. Sweeney P, El-Naggar AK, Lin SH, Pisters LL. Biological significance of c-met over expression in papillary renal cell carcinoma. J Urol. 2002 Jul; 168(1):51-5. PMID: 12050491.
      Citations: 19     Fields:    Translation:Humans
    424. Clifford JL, Walch E, Yang X, Xu X, Alberts DS, Clayman GL, El-Naggar AK, Lotan R, Lippman SM. Suppression of type I interferon signaling proteins is an early event in squamous skin carcinogenesis. Clin Cancer Res. 2002 Jul; 8(7):2067-72. PMID: 12114405.
      Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
    425. Choi HR, Batsakis JG, Callender DL, Prieto VG, Luna MA, El-Naggar AK. Molecular analysis of chromosome 16q regions in dermal analogue tumors of salivary glands: a genetic link to dermal cylindroma? Am J Surg Pathol. 2002 Jun; 26(6):778-83. PMID: 12023583.
      Citations: 6     Fields:    Translation:HumansCells
    426. El-Naggar AK. Methods in molecular surgical pathology. Semin Diagn Pathol. 2002 May; 19(2):56-71. PMID: 12036282.
      Citations: 1     Fields:    Translation:HumansCells
    427. Batsakis JG, Medeiros JL, Luna MA, El-Naggar AK. Plasma cell dyscrasias and the head and neck. Ann Diagn Pathol. 2002 Apr; 6(2):129-40. PMID: 12004363.
      Citations: 10     Fields:    Translation:Humans
    428. Shmulevich I, Hunt K, El-Naggar A, Taylor E, Ramdas L, Hess KR, Pollock R, Zhang W, Labord? P. Tumor specific gene expression profiles in human leiomyosarcoma: an evaluation of intratumor heterogeneity. Cancer. 2002 Apr 01; 94(7):2069-75. PMID: 11932911.
      Citations: 10     Fields:    Translation:Humans
    429. Lott ST, Chandler DS, Curley SA, Foster CJ, El-Naggar A, Frazier M, Strong LC, Lovell M, Killary AM. High frequency loss of heterozygosity in von Hippel-Lindau (VHL)-associated and sporadic pancreatic islet cell tumors: evidence for a stepwise mechanism for malignant conversion in VHL tumorigenesis. Cancer Res. 2002 Apr 01; 62(7):1952-5. PMID: 11929809.
      Citations: 7     Fields:    Translation:HumansCells
    430. Lee JI, Soria JC, Hassan KA, El-Naggar AK, Tang X, Liu DD, Hong WK, Mao L. Loss of PTEN expression as a prognostic marker for tongue cancer. Arch Otolaryngol Head Neck Surg. 2001 Dec; 127(12):1441-5. PMID: 11735811.
      Citations: 40     Fields:    Translation:Humans
    431. Tseng JE, Glisson BS, Khuri FR, Shin DM, Myers JN, El-Naggar AK, Roach JS, Ginsberg LE, Thall PF, Wang X, Teddy S, Lawhorn KN, Zentgraf RE, Steinhaus GD, Pluda JM, Abbruzzese JL, Hong WK, Herbst RS. Phase II study of the antiangiogenesis agent thalidomide in recurrent or metastatic squamous cell carcinoma of the head and neck. Cancer. 2001 Nov 01; 92(9):2364-73. PMID: 11745292.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    432. Hoang MP, Callender DL, Sola Gallego JJ, Huang Z, Sneige N, Luna MA, Batsakis JG, El-Naggar AK. Molecular and biomarker analyses of salivary duct carcinomas: comparison with mammary duct carcinoma. Int J Oncol. 2001 Oct; 19(4):865-71. PMID: 11562768.
      Citations: 14     Fields:    Translation:HumansCells
    433. Papadimitrakopoulou VA, Izzo J, Mao L, Keck J, Hamilton D, Shin DM, El-Naggar A, den Hollander P, Liu D, Hittelman WN, Hong WK. Cyclin D1 and p16 alterations in advanced premalignant lesions of the upper aerodigestive tract: role in response to chemoprevention and cancer development. Clin Cancer Res. 2001 Oct; 7(10):3127-34. PMID: 11595705.
      Citations: 28     Fields:    Translation:HumansCells
    434. Evans SC, Viswanathan M, Grier JD, Narayana M, El-Naggar AK, Lozano G. An alternatively spliced HDM2 product increases p53 activity by inhibiting HDM2. Oncogene. 2001 Jul 05; 20(30):4041-9. PMID: 11494132.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    435. Maciorowski Z, Klijanienko J, Padoy E, Mosseri V, Fourquet A, Chevillard S, El-Naggar AK, Vielh P. Comparative image and flow cytometric TUNEL analysis of fine needle samples of breast carcinoma. Cytometry. 2001 Jun 15; 46(3):150-6. PMID: 11449405.
      Citations: 5     Fields:    Translation:HumansCells
    436. El-Naggar AK, Lai S, Clayman GL, Mims B, Lippman SM, Coombes M, Luna MA, Lozano G. p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas. Carcinogenesis. 2001 May; 22(5):729-35. PMID: 11323391.
      Citations: 5     Fields:    Translation:HumansCells
    437. Spring PM, Myers JN, El-Naggar AK, Langstein HN. Malignant melanoma arising within a burn scar case report and review of the literature. Ann Otol Rhinol Laryngol. 2001 Apr; 110(4):369-76. PMID: 11307915.
      Citations: 3     Fields:    Translation:Humans
    438. Kim J, Shin DM, El-Naggar A, Lee JS, Corrales C, Lippman SM, Hong WK, Hittelman WN. Chromosome polysomy and histological characteristics in oral premalignant lesions. Cancer Epidemiol Biomarkers Prev. 2001 Apr; 10(4):319-25. PMID: 11319171.
      Citations: 5     Fields:    Translation:HumansCells
    439. Pachmann K, Zhao S, Schenk T, Kantarjian H, El-Naggar AK, Siciliano MJ, Guo JQ, Arlinghaus RB, Andreeff M. Expression of bcr-abl mRNA in individual chronic myelogenous leukaemia cells as determined by in situ amplification. Br J Haematol. 2001 Mar; 112(3):749-59. PMID: 11260080.
      Citations:    Fields:    Translation:HumansCells
    440. Servois V, Lussier C, El-Naggar AK, Vielh P, Klijanienko J, Lagac? R. Fine-needle sampling of primary neuroendocrine carcinomas of salivary glands: cytohistological correlations and clinical analysis. Diagn Cytopathol. 2001 Mar; 24(3):163-6. PMID: 11241898.
      Citations: 1     Fields:    Translation:Humans
    441. Slaton JW, Inoue K, Perrotte P, El-Naggar AK, Swanson DA, Fidler IJ, Dinney CP. Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma. Am J Pathol. 2001 Feb; 158(2):735-43. PMID: 11159211; PMCID: PMC1850319.
      Citations: 40     Fields:    Translation:Humans