PAUL J CHIAO

TitleProfessor
InstitutionMD Anderson
DepartmentMolecular & Cellular Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Glorieux C, Xia X, He YQ, Hu Y, Cremer K, Robert A, Liu J, Wang F, Ling J, Chiao PJ, Huang P. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021 01; 38:101780. PMID: 33171331.
      Citations:    Fields:    
    2. Lu Y, Wu M, Fu J, Sun Y, Furukawa K, Ling J, Qin X, Chiao PJ. The overexpression of long intergenic ncRNA00162 induced by RelA/p65 promotes growth of pancreatic ductal adenocarcinoma. Cell Prolif. 2020 May; 53(5):e12805. PMID: 32364285.
      Citations: 1     Fields:    Translation:HumansCells
    3. Hu K, Li K, Lv J, Feng J, Chen J, Wu H, Cheng F, Jiang W, Wang J, Pei H, Chiao PJ, Cai Z, Chen Y, Liu M, Pang X. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 04 01; 130(4):1752-1766. PMID: 31874110.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    4. Ju HQ, Lu YX, Chen DL, Zuo ZX, Liu ZX, Wu QN, Mo HY, Wang ZX, Wang DS, Pu HY, Zeng ZL, Li B, Xie D, Huang P, Hung MC, Chiao PJ, Xu RH. Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications. J Natl Cancer Inst. 2019 Jun 01; 111(6):584-596. PMID: 30534944.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    5. Carruthers D, Ismaily M, Vanderheiden A, Yates M, DeGueme A, Adams-Huet B, Basani S, Abreu M, Lingvay I. DETERMINING INSULIN DOSE AT THE TIME OF DISCHARGE IN A HIGH-RISK POPULATION: IS THERE ROOM FOR IMPROVEMENT? Endocr Pract. 2019 Mar; 25(3):263-269. PMID: 19808866.
      Citations: 15     Fields:    Translation:AnimalsCells
    6. Ling J, Chiao PJ. Two Birds with One Stone: Therapeutic Targeting of IL1a Signaling Pathways in Pancreatic Ductal Adenocarcinoma and the Cancer-Associated Fibroblasts. Cancer Discov. 2019 02; 9(2):173-175. PMID: 30737215.
      Citations: 1     Fields:    Translation:HumansCells
    7. Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, Ramachandran V, Arumugam T, Niehrs C, Wang H, Chiao P, Ling J, Curran MA, Maitra A, Hung MC, Lee JE, Logsdon CD, Hwang RF. Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma. Sci Transl Med. 2018 10 24; 10(464). PMID: 30355799.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    8. Sun Y, Jiang W, Lu W, Song M, Liu K, Chen P, Chang A, Ling J, Chiao PJ, Hu Y, Huang P. Identification of cisplatin sensitizers through high-throughput combinatorial screening. Int J Oncol. 2018 Sep; 53(3):1237-1246. PMID: 29956742.
      Citations: 2     Fields:    Translation:HumansCells
    9. Zhang B, Fu D, Xu Q, Cong X, Wu C, Zhong X, Ma Y, Lv Z, Chen F, Han L, Qian M, Chin YE, Lam EW, Chiao P, Sun Y. The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1. Nat Commun. 2018 04 30; 9(1):1723. PMID: 29712904.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    10. Zhang Y, Zoltan M, Riquelme E, Xu H, Sahin I, Castro-Pando S, Montiel MF, Chang K, Jiang Z, Ling J, Gupta S, Horne W, Pruski M, Wang H, Sun SC, Lozano G, Chiao P, Maitra A, Leach SD, Kolls JK, Vilar E, Wang TC, Bailey JM, McAllister F. Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells. Gastroenterology. 2018 07; 155(1):210-223.e3. PMID: 29604293.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    11. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-Induced and PKCe Monoubiquitylation-Dependent NF-?B Activation Upregulates PKM2 Expression and Promotes Tumorigenesis. Mol Cell. 2018 01 18; 69(2):347. PMID: 29351852.
      Citations: 3     Fields:    
    12. Santoro R, Carbone C, Piro G, Chiao PJ, Melisi D. TAK-ing aim at chemoresistance: The emerging role of MAP3K7 as a target for cancer therapy. Drug Resist Updat. 2017 11; 33-35:36-42. PMID: 29145973.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    13. Zhou H, Qin Y, Ji S, Ling J, Fu J, Zhuang Z, Fan X, Song L, Yu X, Chiao PJ. SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer. Oncogene. 2018 02 15; 37(7):912-923. PMID: 29059173.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    14. Chen DL, Lu YX, Zhang JX, Wei XL, Wang F, Zeng ZL, Pan ZZ, Yuan YF, Wang FH, Pelicano H, Chiao PJ, Huang P, Xie D, Li YH, Ju HQ, Xu RH. Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression. Theranostics. 2017; 7(19):4836-4849. PMID: 29187907.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    15. Zhuang Z, Li H, Lee H, Aguilar M, Gocho T, Ju H, Iida T, Ling J, Fu J, Wu M, Sun Y, Lu Y, Chiao PJ. NEMO peptide inhibits the growth of pancreatic ductal adenocarcinoma by blocking NF-?B activation. Cancer Lett. 2017 12 28; 411:44-56. PMID: 28951128.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    16. Chiao PJ, Ling J, Fu J, Lu Y, Sun YC. Inhibition of Pancreatic Cancer by RhIL1RA-Response. Clin Cancer Res. 2017 06 15; 23(12):3224. PMID: 28620001.
      Citations:    Fields:    Translation:HumansCells
    17. Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, DePinho RA, Huang P, Xu RH, Chiao PJ. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017 02 24; 8:14437. PMID: 28232723.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    18. Budd Haeberlein S, O'Gorman J, Chiao P, Bussière T, von Rosenstiel P, Tian Y, Zhu Y, von Hehn C, Gheuens S, Skordos L, Chen T, Sandrock A. Clinical Development of Aducanumab, an Anti-Aß Human Monoclonal Antibody Being Investigated for the Treatment of Early Alzheimer's Disease. J Prev Alzheimers Dis. 2017; 4(4):255-263. PMID: 29181491.
      Citations: 16     Fields:    Translation:Humans
    19. Gao S, Sun Y, Zhang X, Hu L, Liu Y, Chua CY, Phillips LM, Ren H, Fleming JB, Wang H, Chiao PJ, Hao J, Zhang W. IGFBP2 Activates the NF-?B Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2016 11 15; 76(22):6543-6554. PMID: 27659045.
      Citations: 27     Fields:    Translation:HumansAnimals
    20. Ju HQ, Zhuang ZN, Li H, Tian T, Lu YX, Fan XQ, Zhou HJ, Mo HY, Sheng H, Chiao PJ, Xu RH. Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer. Cancer Lett. 2016 08 28; 379(1):1-11. PMID: 27233476.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    21. Kang Y, Roife D, Lee Y, Lv H, Suzuki R, Ling J, Rios Perez MV, Li X, Dai B, Pratt M, Truty MJ, Chatterjee D, Wang H, Thomas RM, Wang Y, Koay EJ, Chiao PJ, Katz MH, Fleming JB. Transforming Growth Factor-ß Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors. Clin Cancer Res. 2016 Oct 01; 22(19):4934-4946. PMID: 27126993.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    22. Ji S, Qin Y, Liang C, Huang R, Shi S, Liu J, Jin K, Liang D, Xu W, Zhang B, Liu L, Liu C, Xu J, Ni Q, Chiao PJ, Li M, Yu X. FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer. Clin Cancer Res. 2016 08 01; 22(15):3950-60. PMID: 26983463.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    23. Xu Q, Chiao P, Sun Y. Amphiregulin in Cancer: New Insights for Translational Medicine. Trends Cancer. 2016 03; 2(3):111-113. PMID: 28741529.
      Citations: 8     Fields:    Translation:Humans
    24. Zhuang Z, Ju HQ, Aguilar M, Gocho T, Li H, Iida T, Lee H, Fan X, Zhou H, Ling J, Li Z, Fu J, Wu M, Li M, Melisi D, Iwakura Y, Xu K, Fleming JB, Chiao PJ. IL1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-?B Activation. Clin Cancer Res. 2016 Mar 15; 22(6):1432-44. PMID: 26500238.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    25. Ju HQ, Li H, Tian T, Lu YX, Bai L, Chen LZ, Sheng H, Mo HY, Zeng JB, Deng W, Chiao PJ, Xu RH. Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-?B activation. J Pineal Res. 2016 Jan; 60(1):27-38. PMID: 26445000.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    26. Wang P, Zhu CF, Ma MZ, Chen G, Song M, Zeng ZL, Lu WH, Yang J, Wen S, Chiao PJ, Hu Y, Huang P. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget. 2015 Aug 28; 6(25):21148-58. PMID: 26020803.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    27. Sun L, Chua CYX, Tian W, Zhang Z, Chiao PJ, Zhang W. MicroRNA Signaling Pathway Network in Pancreatic Ductal Adenocarcinoma. J Genet Genomics. 2015 Oct 20; 42(10):563-577. PMID: 26554910.
      Citations: 8     Fields:    Translation:HumansCells
    28. Carbone C, Piro G, Fassan M, Tamburrino A, Mina MM, Zanotto M, Chiao PJ, Bassi C, Scarpa A, Tortora G, Melisi D. An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis. Oncotarget. 2015 May 30; 6(15):13822-34. PMID: 25360865.
      Citations: 20     Fields:    Translation:HumansCells
    29. Hargreaves RJ, Hoppin J, Sevigny J, Patel S, Chiao P, Klimas M, Verma A. Optimizing Central Nervous System Drug Development Using Molecular Imaging. Clin Pharmacol Ther. 2015 Jul; 98(1):47-60. PMID: 25869938.
      Citations: 5     Fields:    Translation:Humans
    30. Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, Gao J, Zhang B, Xu W, Liu J, Liang D, Liu L, Liu C, Long J, Zhou H, Chiao PJ, Xu J, Ni Q, Gao D, Yu X. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer. Cell Res. 2015 May; 25(5):561-73. PMID: 25753158.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    31. Ju HQ, Gocho T, Aguilar M, Wu M, Zhuang ZN, Fu J, Yanaga K, Huang P, Chiao PJ. Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation. Mol Cancer Ther. 2015 Mar; 14(3):788-98. PMID: 25527634.
      Citations: 40     Translation:HumansAnimalsCells
    32. Kang Y, Ling J, Suzuki R, Roife D, Chopin-Laly X, Truty MJ, Chatterjee D, Wang H, Thomas RM, Katz MH, Chiao PJ, Fleming JB. SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium. PLoS One. 2014; 9(9):e107948. PMID: 25264609.
      Citations: 9     Fields:    Translation:HumansCells
    33. Chang Z, Ju H, Ling J, Zhuang Z, Li Z, Wang H, Fleming JB, Freeman JW, Yu D, Huang P, Chiao PJ. Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis. PLoS One. 2014; 9(7):e101452. PMID: 25029561.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    34. Blonska M, Joo D, Nurieva RI, Zhao X, Chiao P, Sun SC, Dong C, Lin X. Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKß signaling cascade. Sci Signal. 2013 Dec 17; 6(306):ra110. PMID: 24345681.
      Citations: 5     Fields:    Translation:HumansCells
    35. Bera A, Zhao S, Cao L, Chiao PJ, Freeman JW. Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-?B Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells. PLoS One. 2013; 8(12):e82282. PMID: 24340014.
      Citations: 18     Fields:    Translation:HumansCells
    36. Zhang Y, Yang J, Cui X, Chen Y, Zhu VF, Hagan JP, Wang H, Yu X, Hodges SE, Fang J, Chiao PJ, Logsdon CD, Fisher WE, Brunicardi FC, Chen C, Yao Q, Fernandez-Zapico ME, Li M. A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth. EMBO Mol Med. 2013 Sep; 5(9):1322-34. PMID: 23857777.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    37. Chang Z, Li Z, Wang X, Kang Y, Yuan Y, Niu J, Wang H, Chatterjee D, Fleming JB, Li M, Abbruzzese JL, Chiao PJ. Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells. Clin Cancer Res. 2013 Feb 01; 19(3):549-59. PMID: 23340292.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    38. Zhang Y, Chen L, Yang J, Fleming JB, Chiao PJ, Logsdon CD, Li M. Study human pancreatic cancer in mice: how close are they? Biochim Biophys Acta. 2013 Jan; 1835(1):110-8. PMID: 23147198.
      Citations: 6     Fields:    Translation:HumansAnimals
    39. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-induced and PKCe monoubiquitylation-dependent NF-?B activation upregulates PKM2 expression and promotes tumorigenesis. Mol Cell. 2012 Dec 14; 48(5):771-84. PMID: 23123196.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    40. Fujioka S, Son K, Onda S, Schmidt C, Scrabas GM, Okamoto T, Fujita T, Chiao PJ, Yanaga K. Desensitization of NF?B for overcoming chemoresistance of pancreatic cancer cells to TNF-a or paclitaxel. Anticancer Res. 2012 Nov; 32(11):4813-21. PMID: 23155247.
      Citations: 8     Fields:    Translation:HumansCells
    41. Ling J, Kang Y, Zhao R, Xia Q, Lee DF, Chang Z, Li J, Peng B, Fleming JB, Wang H, Liu J, Lemischka IR, Hung MC, Chiao PJ. KrasG12D-induced IKK2/ß/NF-?B activation by IL-1a and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 2012 Jan 17; 21(1):105-20. PMID: 22264792.
      Citations: 216     Fields:    Translation:HumansAnimalsCells
    42. Hu Y, Lu W, Chen G, Wang P, Chen Z, Zhou Y, Ogasawara M, Trachootham D, Feng L, Pelicano H, Chiao PJ, Keating MJ, Garcia-Manero G, Huang P. K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis. Cell Res. 2012 Feb; 22(2):399-412. PMID: 21876558.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    43. Melisi D, Xia Q, Paradiso G, Ling J, Moccia T, Carbone C, Budillon A, Abbruzzese JL, Chiao PJ. Modulation of pancreatic cancer chemoresistance by inhibition of TAK1. J Natl Cancer Inst. 2011 Aug 03; 103(15):1190-204. PMID: 21743023.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    44. Carbone C, Moccia T, Zhu C, Paradiso G, Budillon A, Chiao PJ, Abbruzzese JL, Melisi D. Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype. Clin Cancer Res. 2011 Sep 01; 17(17):5822-32. PMID: 21737511.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    45. Chiao PJ, Ling J. Kras, Pten, NF-?B, and inflammation: dangerous liaisons. Cancer Discov. 2011 Jul; 1(2):103-5. PMID: 22586351.
      Citations: 5     Fields:    Translation:HumansAnimals
    46. Shim DJ, Yang L, Reed JG, Noebels JL, Chiao PJ, Zheng H. Disruption of the NF-?B/I?Ba Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons. Mol Neurodegener. 2011 Jun 10; 6:42. PMID: 21663635.
      Citations: 10     Fields:    
    47. Yang G, Xiao X, Rosen DG, Cheng X, Wu X, Chang B, Liu G, Xue F, Mercado-Uribe I, Chiao P, Du X, Liu J. The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer. Clin Cancer Res. 2011 Apr 15; 17(8):2181-94. PMID: 21339307.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    48. Peng B, Ling J, Lee AJ, Wang Z, Chang Z, Jin W, Kang Y, Zhang R, Shim D, Wang H, Fleming JB, Zheng H, Sun SC, Chiao PJ. Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15193-8. PMID: 20696914.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    49. Son K, Fujioka S, Iida T, Furukawa K, Fujita T, Yamada H, Chiao PJ, Yanaga K. Doxycycline induces apoptosis in PANC-1 pancreatic cancer cells. Anticancer Res. 2009 Oct; 29(10):3995-4003. PMID: 19846942.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    50. Li Z, Chang Z, Chiao LJ, Kang Y, Xia Q, Zhu C, Fleming JB, Evans DB, Chiao PJ. TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation. Cancer Res. 2009 Oct 01; 69(19):7851-9. PMID: 19773448.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    51. Lu J, Guo H, Treekitkarnmongkol W, Li P, Zhang J, Shi B, Ling C, Zhou X, Chen T, Chiao PJ, Feng X, Seewaldt VL, Muller WJ, Sahin A, Hung MC, Yu D. 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell. 2009 Sep 08; 16(3):195-207. PMID: 19732720.
      Citations: 100     Fields:    Translation:HumansCells
    52. Uwagawa T, Chiao PJ, Gocho T, Hirohara S, Misawa T, Yanaga K. Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation. Anticancer Res. 2009 Aug; 29(8):3173-8. PMID: 19661331.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    53. Melisi D, Niu J, Chang Z, Xia Q, Peng B, Ishiyama S, Evans DB, Chiao PJ. Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB. Mol Cancer Res. 2009 May; 7(5):624-33. PMID: 19435817.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    54. Melisi D, Ishiyama S, Sclabas GM, Fleming JB, Xia Q, Tortora G, Abbruzzese JL, Chiao PJ. LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis. Mol Cancer Ther. 2008 Apr; 7(4):829-40. PMID: 18413796.
      Citations: 132     Translation:HumansAnimalsCells
    55. Xie X, Xia W, Li Z, Kuo HP, Liu Y, Li Z, Ding Q, Zhang S, Spohn B, Yang Y, Wei Y, Lang JY, Evans DB, Chiao PJ, Abbruzzese JL, Hung MC. Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. Cancer Cell. 2007 Jul; 12(1):52-65. PMID: 17613436.
      Citations: 38     Fields:    Translation:Animals
    56. Ricci MS, Kim SH, Ogi K, Plastaras JP, Ling J, Wang W, Jin Z, Liu YY, Dicker DT, Chiao PJ, Flaherty KT, Smith CD, El-Deiry WS. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer Cell. 2007 Jul; 12(1):66-80. PMID: 17613437.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    57. Uwagawa T, Li Z, Chang Z, Xia Q, Peng B, Sclabas GM, Ishiyama S, Hung MC, Evans DB, Abbruzzese JL, Chiao PJ. Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. Cancer. 2007 May 15; 109(10):2142-53. PMID: 17410536.
      Citations: 12     Fields:    Translation:HumansCells
    58. Oida Y, Gopalan B, Miyahara R, Branch CD, Chiao P, Chada S, Ramesh R. Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation. Mol Cancer Ther. 2007 Apr; 6(4):1440-9. PMID: 17431123.
      Citations: 5     Translation:HumansAnimalsCells
    59. Banerjee S, Zhang Y, Wang Z, Che M, Chiao PJ, Abbruzzese JL, Sarkar FH. In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. Int J Cancer. 2007 Feb 15; 120(4):906-17. PMID: 17131310.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    60. Melisi D, Chiao PJ. NF-kappa B as a target for cancer therapy. Expert Opin Ther Targets. 2007 Feb; 11(2):133-44. PMID: 17227230.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    61. Niu J, Chang Z, Peng B, Xia Q, Lu W, Huang P, Tsao MS, Chiao PJ. Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. J Biol Chem. 2007 Mar 02; 282(9):6001-11. PMID: 17200110.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    62. Xia D, Srinivas H, Ahn YH, Sethi G, Sheng X, Yung WK, Xia Q, Chiao PJ, Kim H, Brown PH, Wistuba II, Aggarwal BB, Kurie JM. Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway. J Biol Chem. 2007 Feb 09; 282(6):3507-19. PMID: 17158870.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    63. Trachootham D, Zhou Y, Zhang H, Demizu Y, Chen Z, Pelicano H, Chiao PJ, Achanta G, Arlinghaus RB, Liu J, Huang P. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell. 2006 Sep; 10(3):241-52. PMID: 16959615.
      Citations: 379     Fields:    Translation:HumansAnimalsCells
    64. Kouvaraki MA, Korapati AL, Rassidakis GZ, Tian L, Zhang Q, Chiao P, Ho L, Evans DB, Claret FX. Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma. Cancer Res. 2006 Sep 01; 66(17):8581-9. PMID: 16951171.
      Citations: 23     Fields:    Translation:Humans
    65. Choi W, Proctor L, Xia Q, Feng Y, Gerner EW, Chiao PJ, Hamilton SR, Zhang W. Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. Mol Carcinog. 2006 Sep; 45(9):685-93. PMID: 16637064.
      Citations: 4     Fields:    Translation:HumansCells
    66. Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE. Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. Angiogenesis. 2006; 9(2):101-10. PMID: 16871430.
      Citations: 21     Fields:    Translation:HumansCells
    67. Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Andtbacka RH, Dunner K, Pal A, Bornmann WG, Chiao PJ, Huang P, Xiong H, Abbruzzese JL, McConkey DJ. Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells. Cancer Res. 2006 Apr 01; 66(7):3773-81. PMID: 16585204.
      Citations: 97     Fields:    Translation:HumansAnimals
    68. Gao Z, He Q, Peng B, Chiao PJ, Ye J. Regulation of nuclear translocation of HDAC3 by IkappaBalpha is required for tumor necrosis factor inhibition of peroxisome proliferator-activated receptor gamma function. J Biol Chem. 2006 Feb 17; 281(7):4540-7. PMID: 16371367.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    69. Nawrocki ST, Carew JS, Dunner K, Boise LH, Chiao PJ, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Res. 2005 Dec 15; 65(24):11510-9. PMID: 16357160.
      Citations: 107     Fields:    Translation:HumansCells
    70. Banerjee S, Zhang Y, Ali S, Bhuiyan M, Wang Z, Chiao PJ, Philip PA, Abbruzzese J, Sarkar FH. Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer. Cancer Res. 2005 Oct 01; 65(19):9064-72. PMID: 16204081.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    71. Zhu H, Zhang L, Dong F, Guo W, Wu S, Teraishi F, Davis JJ, Chiao PJ, Fang B. Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors. Oncogene. 2005 Jul 21; 24(31):4993-9. PMID: 15824729.
      Citations: 41     Fields:    Translation:HumansCells
    72. Yokoi K, Kim SJ, Thaker P, Yazici S, Nam DH, He J, Sasaki T, Chiao PJ, Sclabas GM, Abbruzzese JL, Hamilton SR, Fidler IJ. Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. Neoplasia. 2005 Jul; 7(7):696-704. PMID: 16026649.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    73. Qian J, Niu J, Li M, Chiao PJ, Tsao MS. In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Res. 2005 Jun 15; 65(12):5045-53. PMID: 15958547.
      Citations: 58     Fields:    Translation:HumansCells
    74. Sclabas GM, Uwagawa T, Schmidt C, Hess KR, Evans DB, Abbruzzese JL, Chiao PJ. Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin. Cancer. 2005 Jun 15; 103(12):2485-90. PMID: 15861417.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    75. Gao Z, Chiao P, Zhang X, Zhang X, Lazar MA, Seto E, Young HA, Ye J. Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter. J Biol Chem. 2005 Jun 03; 280(22):21091-8. PMID: 15811852.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    76. Xiao Y, Zhong Y, Su H, Zhou Z, Chiao P, Zhong G. NF-kappa B activation is not required for Chlamydia trachomatis inhibition of host epithelial cell apoptosis. J Immunol. 2005 Feb 01; 174(3):1701-8. PMID: 15661934.
      Citations: 24     Fields:    Translation:HumansCells
    77. Li Z, Niu J, Uwagawa T, Peng B, Chiao PJ. Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response. J Biol Chem. 2005 Apr 29; 280(17):16843-50. PMID: 15671037.
      Citations: 22     Fields:    Translation:HumansCells
    78. Sclabas GM, Fujioka S, Schmidt C, Li Z, Frederick WA, Yang W, Yokoi K, Evans DB, Abbruzzese JL, Hess KR, Zhang W, Fidler IJ, Chiao PJ. Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. Clin Cancer Res. 2005 Jan 15; 11(2 Pt 1):440-9. PMID: 15701826.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    79. Chiao PJ, Schmidt C. Open Access gains attention in scholar communication. Mol Cancer. 2004 Sep 06; 3:23. PMID: 15350204.
      Citations: 1     Fields:    
    80. Fujioka S, Niu J, Schmidt C, Sclabas GM, Peng B, Uwagawa T, Li Z, Evans DB, Abbruzzese JL, Chiao PJ. NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity. Mol Cell Biol. 2004 Sep; 24(17):7806-19. PMID: 15314185.
      Citations: 126     Fields:    Translation:HumansAnimalsCells
    81. Munshi A, Kurland JF, Nishikawa T, Chiao PJ, Andreeff M, Meyn RE. Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells. Mol Cancer Ther. 2004 Aug; 3(8):985-92. PMID: 15299081.
      Citations: 20     Translation:HumansCells
    82. Li Z, Sclabas GM, Peng B, Hess KR, Abbruzzese JL, Evans DB, Chiao PJ. Overexpression of synuclein-gamma in pancreatic adenocarcinoma. Cancer. 2004 Jul 01; 101(1):58-65. PMID: 15221989.
      Citations: 23     Fields:    Translation:HumansCells
    83. Zhu H, Zhang L, Huang X, Davis JJ, Jacob DA, Teraishi F, Chiao P, Fang B. Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms. Mol Ther. 2004 May; 9(5):666-73. PMID: 15120327.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    84. Fujioka S, Schmidt C, Sclabas GM, Li Z, Pelicano H, Peng B, Yao A, Niu J, Zhang W, Evans DB, Abbruzzese JL, Huang P, Chiao PJ. Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. J Biol Chem. 2004 Jun 25; 279(26):27549-59. PMID: 15102862.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    85. Niu J, Li Z, Peng B, Chiao PJ. Identification of an autoregulatory feedback pathway involving interleukin-1alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells. J Biol Chem. 2004 Apr 16; 279(16):16452-62. PMID: 14679213.
      Citations: 39     Fields:    Translation:HumansCells
    86. Schmidt C, Peng B, Li Z, Sclabas GM, Fujioka S, Niu J, Schmidt-Supprian M, Evans DB, Abbruzzese JL, Chiao PJ. Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. Mol Cell. 2003 Nov; 12(5):1287-300. PMID: 14636585.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    87. Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ. Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. Oncogene. 2003 Mar 06; 22(9):1365-70. PMID: 12618762.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    88. Sclabas GM, Fujioka S, Schmidt C, Fan Z, Evans DB, Chiao PJ. Restoring apoptosis in pancreatic cancer cells by targeting the nuclear factor-kappaB signaling pathway with the anti-epidermal growth factor antibody IMC-C225. J Gastrointest Surg. 2003 Jan; 7(1):37-43; discussion 43. PMID: 12559183.
      Citations: 12     Fields:    Translation:HumansCells
    89. Fujioka S, Sclabas GM, Schmidt C, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ. Function of nuclear factor kappaB in pancreatic cancer metastasis. Clin Cancer Res. 2003 Jan; 9(1):346-54. PMID: 12538487.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    90. Sclabas GM, Fujioka S, Schmidt C, Evans DB, Chiao PJ. NF-kappaB in pancreatic cancer. Int J Gastrointest Cancer. 2003; 33(1):15-26. PMID: 12909735.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    91. Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. Clin Cancer Res. 2002 Nov; 8(11):3628-38. PMID: 12429655.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    92. Chiao PJ, Na R, Niu J, Sclabas GM, Dong Q, Curley SA. Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells. Cancer. 2002 Oct 15; 95(8):1696-705. PMID: 12365017.
      Citations: 22     Fields:    Translation:HumansCells
    93. Dong QG, Sclabas GM, Fujioka S, Schmidt C, Peng B, Wu T, Tsao MS, Evans DB, Abbruzzese JL, McDonnell TJ, Chiao PJ. The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. Oncogene. 2002 Sep 19; 21(42):6510-9. PMID: 12226754.
      Citations: 47     Fields:    Translation:HumansCells
    94. Vorburger SA, Pataer A, Yoshida K, Barber GN, Xia W, Chiao P, Ellis LM, Hung MC, Swisher SG, Hunt KK. Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis. Oncogene. 2002 Sep 12; 21(41):6278-88. PMID: 12214268.
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    95. Pearson AS, Chiao P, Zhang L, Zhang W, Larry L, Katz RL, Evans DB, Abbruzzese JL. The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration. Int J Oncol. 2000 Aug; 17(2):381-5. PMID: 10891550.
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    96. Wolff RA, Chiao P, Lenzi R, Pisters PW, Lee JE, Janjan NA, Crane CH, Evans DB, Abbruzzese JL. Current approaches and future strategies for pancreatic carcinoma. Invest New Drugs. 2000 Feb; 18(1):43-56. PMID: 10830140.
      Citations: 9     Fields:    Translation:HumansAnimals
    97. Wang W, Abbruzzese JL, Evans DB, Chiao PJ. Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. Oncogene. 1999 Aug 12; 18(32):4554-63. PMID: 10467400.
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    98. Feig BW, Lu X, Hunt KK, Shan Q, Yu D, Pollock R, Chiao P. Inhibition of the transcription factor nuclear factor-kappa B by adenoviral-mediated expression of I kappa B alpha M results in tumor cell death. Surgery. 1999 Aug; 126(2):399-405. PMID: 10455913.
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    99. Shao R, Hu MC, Zhou BP, Lin SY, Chiao PJ, von Lindern RH, Spohn B, Hung MC. E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities. J Biol Chem. 1999 Jul 30; 274(31):21495-8. PMID: 10419449.
      Citations: 21     Fields:    Translation:HumansCells
    100. Chiao PJ, Hunt KK, Grau AM, Abramian A, Fleming J, Zhang W, Breslin T, Abbruzzese JL, Evans DB. Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle. Ann N Y Acad Sci. 1999 Jun 30; 880:31-7. PMID: 10415848.
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    101. Bold RJ, Hess KR, Pearson AS, Grau AM, Sinicrope FA, Jennings M, McConkey DJ, Bucana CD, Cleary KR, Hallin PA, Chiao PJ, Abbruzzese JL, Evans DB. Prognostic factors in resectable pancreatic cancer: p53 and bcl-2. J Gastrointest Surg. 1999 May-Jun; 3(3):263-77. PMID: 10481119.
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    102. Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR, Chiao PJ. The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res. 1999 Jan; 5(1):119-27. PMID: 9918209.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    103. Hunt KK, Fleming JB, Abramian A, Zhang L, Evans DB, Chiao PJ. Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells. Cancer Res. 1998 Dec 15; 58(24):5656-61. PMID: 9865717.
      Citations: 10     Fields:    Translation:HumansCells
    104. Bouvet M, Bold RJ, Lee J, Evans DB, Abbruzzese JL, Chiao PJ, McConkey DJ, Chandra J, Chada S, Fang B, Roth JA. Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments]. Ann Surg Oncol. 1998 Dec; 5(8):681-8. PMID: 9869513.
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    105. Robinson EK, Grau AM, Evans DB, Smid CM, Chiao PJ, Abbruzzese JL, Grimm EA. Cell cycle regulation of human pancreatic cancer by tamoxifen. Ann Surg Oncol. 1998 Jun; 5(4):342-9. PMID: 9641456.
      Citations: 4     Fields:    Translation:HumansCells
    106. Deyo JE, Chiao PJ, Tainsky MA. drp, a novel protein expressed at high cell density but not during growth arrest. DNA Cell Biol. 1998 May; 17(5):437-47. PMID: 9628587.
      Citations: 5     Fields:    Translation:HumansCells
    107. Ruan S, Okcu MF, Ren JP, Chiao P, Andreeff M, Levin V, Zhang W. Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin. Cancer Res. 1998 Apr 01; 58(7):1538-43. PMID: 9537261.
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    108. Wang M, Abbruzzese JL, Friess H, Hittelman WN, Evans DB, Abbruzzese MC, Chiao P, Li D. DNA adducts in human pancreatic tissues and their potential role in carcinogenesis. Cancer Res. 1998 Jan 01; 58(1):38-41. PMID: 9426054.
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    109. Miller AR, Robinson EK, Lee JE, Pisters PW, Chiao PJ, Lenzi RL, Abbruzzese JL, Evans DB. Neoadjuvant chemoradiation for adenocarcinoma of the pancreas. Surg Oncol Clin N Am. 1998 Jan; 7(1):183-97. PMID: 9443995.
      Citations: 5     Fields:    Translation:Humans
    110. Shao R, Karunagaran D, Zhou BP, Li K, Lo SS, Deng J, Chiao P, Hung MC. Inhibition of nuclear factor-kappaB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis. J Biol Chem. 1997 Dec 26; 272(52):32739-42. PMID: 9407046.
      Citations: 17     Fields:    Translation:HumansCells
    111. Herrmann JL, Beham AW, Sarkiss M, Chiao PJ, Rands MT, Bruckheimer EM, Brisbay S, McDonnell TJ. Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway. Exp Cell Res. 1997 Nov 25; 237(1):101-9. PMID: 9417872.
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    112. Grau AM, Zhang L, Wang W, Ruan S, Evans DB, Abbruzzese JL, Zhang W, Chiao PJ. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. Cancer Res. 1997 Sep 15; 57(18):3929-34. PMID: 9307274.
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    113. Balch G, Izzo F, Chiao P, Klostergaard J, Curley SA. Activation of human Kupffer cells by thymostimulin (TP-1) to produce cytotoxicity against human hepatocellular cancer. Ann Surg Oncol. 1997 Mar; 4(2):149-55. PMID: 9084852.
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    114. Evans DB, Lee JE, Pisters PW, Charnsangavej C, Ellis LM, Chiao PJ, Lenzi R, Abbruzzese JL. Advances in the diagnosis and treatment of adenocarcinoma of the pancreas. Cancer Treat Res. 1997; 90:109-25. PMID: 9367080.
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    115. Eldredge ER, Chiao PJ, Lu KP. Use of tetracycline operator system to regulate oncogene expression in mammalian cells. Methods Enzymol. 1995; 254:481-91. PMID: 8531708.
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    116. Kannan P, Buettner R, Chiao PJ, Yim SO, Sarkiss M, Tainsky MA. N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation. Genes Dev. 1994 Jun 01; 8(11):1258-69. PMID: 7926729.
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    117. Miyamoto S, Chiao PJ, Verma IM. Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines. Mol Cell Biol. 1994 May; 14(5):3276-82. PMID: 8164680.
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    118. Chiao PJ, Miyamoto S, Verma IM. Autoregulation of I kappa B alpha activity. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):28-32. PMID: 8278379.
      Citations: 126     Fields:    Translation:AnimalsCells
    119. Shin DM, Chiao PJ, Sacks PG, Shin HJ, Hong WK, Hittelman WN, Tainsky MA. Activation of ribosomal protein S2 gene expression in a hamster model of chemically induced oral carcinogenesis. Carcinogenesis. 1993 Jan; 14(1):163-6. PMID: 8425267.
      Citations: 2     Fields:    Translation:AnimalsCells
    120. Kerr LD, Duckett CS, Wamsley P, Zhang Q, Chiao P, Nabel G, McKeithan TW, Baeuerle PA, Verma IM. The proto-oncogene bcl-3 encodes an I kappa B protein. Genes Dev. 1992 Dec; 6(12A):2352-63. PMID: 1459457.
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    121. Chiao PJ, Shin DM, Sacks PG, Hong WK, Tainsky MA. Elevated expression of the ribosomal protein S2 gene in human tumors. Mol Carcinog. 1992; 5(3):219-31. PMID: 1586449.
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    122. Tainsky MA, Yim SO, Krizman DB, Kannan P, Chiao PJ, Mukhopadhyay T, Buettner R. Modulation of differentiation in PA-1 human teratocarcinoma cells after N-ras oncogene-induced tumorigenicity. Oncogene. 1991 Sep; 6(9):1575-82. PMID: 1681491.
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    123. Chiao PJ, Kannan P, Yim SO, Krizman DB, Wu TA, Gallick GE, Tainsky MA. Susceptibility to ras oncogene transformation is coregulated with signal transduction through growth factor receptors. Oncogene. 1991 May; 6(5):713-20. PMID: 1646984.
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    125. Tainsky MA, Krizman DB, Chiao PJ, Yim SO, Giovanella BC. PA-1, a human cell model for multistage carcinogenesis: oncogenes and other factors. Anticancer Res. 1988 Sep-Oct; 8(5A):899-913. PMID: 3052262.
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    126. Rogers WL, Clinthorne NH, Shao L, Chiao P, Ding Y, Stamos JA, Koral KF. SPRINT II: a second generation single photon ring tomograph. IEEE Trans Med Imaging. 1988; 7(4):291-7. PMID: 18230481.
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    127. FBW7 (F-box and WD Repeat Domain-Containing 7) negatively regulates glucose metabolism by targeting the c-Myc/TXNIP (Thioredoxin-binding protein) axis in pancreatic cancer. Clinical Cancer Research. 22:3950-3960.
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    130. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget. 6:21148-21158.
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    132. Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer. Cancer Letters. 379:1-11.
    133. IGFBP2 activates the NF-κB pathway to drive epithelial-mesenchymal transition and invasive character in pancreatic ductal adenocarcinoma. Cancer Research. 76:6543-6554.
    134. IL1 receptor antagonist inhibits pancreatic cancer growth by abrogating NF-κB activation. Clinical Cancer Research. 22:1432-1444.
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