InstitutionMD Anderson
DepartmentMolecular & Cellular Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chen Y, Capello M, Rios Perez MV, Vykoukal JV, Roife D, Kang Y, Prakash LR, Katayama H, Irajizad E, Fleury A, Ferri-Borgogno S, Baluya DL, Dennison JB, Do KA, Fiehn O, Maitra A, Wang H, Chiao PJ, Katz MHG, Fleming JB, Hanash SM, Fahrmann JF. CES2 sustains HNF4a expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop. Mol Metab. 2022 02; 56:101426. PMID: 34971802.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Garlapati P, Ling J, Chiao PJ, Fu J. Circular RNAs regulate cancer-related signaling pathways and serve as potential diagnostic biomarkers for human cancers. Cancer Cell Int. 2021 Jun 23; 21(1):317. PMID: 34162394.
      Citations: 2     
    3. Glorieux C, Xia X, He YQ, Hu Y, Cremer K, Robert A, Liu J, Wang F, Ling J, Chiao PJ, Huang P. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021 01; 38:101780. PMID: 33171331.
      Citations: 10     Fields:    Translation:HumansCells
    4. Capello M, Fahrmann JF, Rios Perez MV, Vykoukal JV, Irajizad E, Tripathi SC, Roife D, Bantis LE, Kang Y, Kundnani DL, Xu H, Prakash LR, Long JP, Katayama H, Fleury A, Ferri-Borgogno S, Baluya DL, Dennison JB, Aguilar-Bonavides C, Casabar JP, Celiktas M, Do KA, Fiehn O, Maitra A, Wang H, Feng Z, Chiao PJ, Katz MH, Fleming JB, Hanash SM. CES2 Expression in Pancreatic Adenocarcinoma Is Predictive of Response to Irinotecan and Is Associated With Type 2 Diabetes. JCO Precis Oncol. 2020 Nov; 4:426-436. PMID: 35050739.
      Citations: 1     Fields:    
    5. Lu Y, Wu M, Fu J, Sun Y, Furukawa K, Ling J, Qin X, Chiao PJ. The overexpression of long intergenic ncRNA00162 induced by RelA/p65 promotes growth of pancreatic ductal adenocarcinoma. Cell Prolif. 2020 May; 53(5):e12805. PMID: 32364285.
      Citations: 2     Fields:    Translation:HumansCells
    6. Hu K, Li K, Lv J, Feng J, Chen J, Wu H, Cheng F, Jiang W, Wang J, Pei H, Chiao PJ, Cai Z, Chen Y, Liu M, Pang X. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 04 01; 130(4):1752-1766. PMID: 31874110.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    7. Ju HQ, Lu YX, Chen DL, Zuo ZX, Liu ZX, Wu QN, Mo HY, Wang ZX, Wang DS, Pu HY, Zeng ZL, Li B, Xie D, Huang P, Hung MC, Chiao PJ, Xu RH. Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications. J Natl Cancer Inst. 2019 Jun 01; 111(6):584-596. PMID: 30534944.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    8. Ling J, Chiao PJ. Two Birds with One Stone: Therapeutic Targeting of IL1a Signaling Pathways in Pancreatic Ductal Adenocarcinoma and the Cancer-Associated Fibroblasts. Cancer Discov. 2019 02; 9(2):173-175. PMID: 30737215.
      Citations: 5     Fields:    Translation:HumansCells
    9. Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, Ramachandran V, Arumugam T, Niehrs C, Wang H, Chiao P, Ling J, Curran MA, Maitra A, Hung MC, Lee JE, Logsdon CD, Hwang RF. Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma. Sci Transl Med. 2018 10 24; 10(464). PMID: 30355799.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    10. Sun Y, Jiang W, Lu W, Song M, Liu K, Chen P, Chang A, Ling J, Chiao PJ, Hu Y, Huang P. Identification of cisplatin sensitizers through high-throughput combinatorial screening. Int J Oncol. 2018 Sep; 53(3):1237-1246. PMID: 29956742.
      Citations: 4     Fields:    Translation:HumansCells
    11. Zhang B, Fu D, Xu Q, Cong X, Wu C, Zhong X, Ma Y, Lv Z, Chen F, Han L, Qian M, Chin YE, Lam EW, Chiao P, Sun Y. The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1. Nat Commun. 2018 04 30; 9(1):1723. PMID: 29712904.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    12. Zhang Y, Zoltan M, Riquelme E, Xu H, Sahin I, Castro-Pando S, Montiel MF, Chang K, Jiang Z, Ling J, Gupta S, Horne W, Pruski M, Wang H, Sun SC, Lozano G, Chiao P, Maitra A, Leach SD, Kolls JK, Vilar E, Wang TC, Bailey JM, McAllister F. Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells. Gastroenterology. 2018 07; 155(1):210-223.e3. PMID: 29604293.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    13. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-Induced and PKCe Monoubiquitylation-Dependent NF-?B Activation Upregulates PKM2 Expression and Promotes Tumorigenesis. Mol Cell. 2018 01 18; 69(2):347. PMID: 29351852.
      Citations: 6     Fields:    
    14. Santoro R, Carbone C, Piro G, Chiao PJ, Melisi D. TAK-ing aim at chemoresistance: The emerging role of MAP3K7 as a target for cancer therapy. Drug Resist Updat. 2017 11; 33-35:36-42. PMID: 29145973.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    15. Zhou H, Qin Y, Ji S, Ling J, Fu J, Zhuang Z, Fan X, Song L, Yu X, Chiao PJ. SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer. Oncogene. 2018 02 15; 37(7):912-923. PMID: 29059173.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    16. Chen DL, Lu YX, Zhang JX, Wei XL, Wang F, Zeng ZL, Pan ZZ, Yuan YF, Wang FH, Pelicano H, Chiao PJ, Huang P, Xie D, Li YH, Ju HQ, Xu RH. Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression. Theranostics. 2017; 7(19):4836-4849. PMID: 29187907.
      Citations: 133     Fields:    Translation:HumansAnimalsCells
    17. Zhuang Z, Li H, Lee H, Aguilar M, Gocho T, Ju H, Iida T, Ling J, Fu J, Wu M, Sun Y, Lu Y, Chiao PJ. NEMO peptide inhibits the growth of pancreatic ductal adenocarcinoma by blocking NF-?B activation. Cancer Lett. 2017 12 28; 411:44-56. PMID: 28951128.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    18. Chiao PJ, Ling J, Fu J, Lu Y, Sun YC. Inhibition of Pancreatic Cancer by RhIL1RA-Response. Clin Cancer Res. 2017 06 15; 23(12):3224. PMID: 28620001.
      Citations:    Fields:    Translation:HumansCells
    19. Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, DePinho RA, Huang P, Xu RH, Chiao PJ. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017 02 24; 8:14437. PMID: 28232723.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    20. Gao S, Sun Y, Zhang X, Hu L, Liu Y, Chua CY, Phillips LM, Ren H, Fleming JB, Wang H, Chiao PJ, Hao J, Zhang W. IGFBP2 Activates the NF-?B Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2016 11 15; 76(22):6543-6554. PMID: 27659045.
      Citations: 42     Fields:    Translation:HumansAnimals
    21. Ju HQ, Zhuang ZN, Li H, Tian T, Lu YX, Fan XQ, Zhou HJ, Mo HY, Sheng H, Chiao PJ, Xu RH. Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer. Cancer Lett. 2016 08 28; 379(1):1-11. PMID: 27233476.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    22. Kang Y, Roife D, Lee Y, Lv H, Suzuki R, Ling J, Rios Perez MV, Li X, Dai B, Pratt M, Truty MJ, Chatterjee D, Wang H, Thomas RM, Wang Y, Koay EJ, Chiao PJ, Katz MH, Fleming JB. Transforming Growth Factor-ß Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors. Clin Cancer Res. 2016 Oct 01; 22(19):4934-4946. PMID: 27126993.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    23. Ji S, Qin Y, Liang C, Huang R, Shi S, Liu J, Jin K, Liang D, Xu W, Zhang B, Liu L, Liu C, Xu J, Ni Q, Chiao PJ, Li M, Yu X. FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer. Clin Cancer Res. 2016 08 01; 22(15):3950-60. PMID: 26983463.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    24. Xu Q, Chiao P, Sun Y. Amphiregulin in Cancer: New Insights for Translational Medicine. Trends Cancer. 2016 03; 2(3):111-113. PMID: 28741529.
      Citations: 11     Fields:    Translation:Humans
    25. Zhuang Z, Ju HQ, Aguilar M, Gocho T, Li H, Iida T, Lee H, Fan X, Zhou H, Ling J, Li Z, Fu J, Wu M, Li M, Melisi D, Iwakura Y, Xu K, Fleming JB, Chiao PJ. IL1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-?B Activation. Clin Cancer Res. 2016 Mar 15; 22(6):1432-44. PMID: 26500238.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    26. Ju HQ, Li H, Tian T, Lu YX, Bai L, Chen LZ, Sheng H, Mo HY, Zeng JB, Deng W, Chiao PJ, Xu RH. Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-?B activation. J Pineal Res. 2016 Jan; 60(1):27-38. PMID: 26445000.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    27. Wang P, Zhu CF, Ma MZ, Chen G, Song M, Zeng ZL, Lu WH, Yang J, Wen S, Chiao PJ, Hu Y, Huang P. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget. 2015 Aug 28; 6(25):21148-58. PMID: 26020803.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    28. Sun L, Chua CYX, Tian W, Zhang Z, Chiao PJ, Zhang W. MicroRNA Signaling Pathway Network in Pancreatic Ductal Adenocarcinoma. J Genet Genomics. 2015 Oct 20; 42(10):563-577. PMID: 26554910.
      Citations: 10     Fields:    Translation:HumansCells
    29. Carbone C, Piro G, Fassan M, Tamburrino A, Mina MM, Zanotto M, Chiao PJ, Bassi C, Scarpa A, Tortora G, Melisi D. An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis. Oncotarget. 2015 May 30; 6(15):13822-34. PMID: 25360865.
      Citations: 23     Fields:    Translation:HumansCells
    30. Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, Gao J, Zhang B, Xu W, Liu J, Liang D, Liu L, Liu C, Long J, Zhou H, Chiao PJ, Xu J, Ni Q, Gao D, Yu X. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer. Cell Res. 2015 May; 25(5):561-73. PMID: 25753158.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    31. Ju HQ, Gocho T, Aguilar M, Wu M, Zhuang ZN, Fu J, Yanaga K, Huang P, Chiao PJ. Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation. Mol Cancer Ther. 2015 Mar; 14(3):788-98. PMID: 25527634.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    32. Kang Y, Ling J, Suzuki R, Roife D, Chopin-Laly X, Truty MJ, Chatterjee D, Wang H, Thomas RM, Katz MH, Chiao PJ, Fleming JB. SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium. PLoS One. 2014; 9(9):e107948. PMID: 25264609.
      Citations: 14     Fields:    Translation:HumansCells
    33. Chang Z, Ju H, Ling J, Zhuang Z, Li Z, Wang H, Fleming JB, Freeman JW, Yu D, Huang P, Chiao PJ. Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis. PLoS One. 2014; 9(7):e101452. PMID: 25029561.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    34. Blonska M, Joo D, Nurieva RI, Zhao X, Chiao P, Sun SC, Dong C, Lin X. Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKß signaling cascade. Sci Signal. 2013 Dec 17; 6(306):ra110. PMID: 24345681.
      Citations: 6     Fields:    Translation:HumansCells
    35. Bera A, Zhao S, Cao L, Chiao PJ, Freeman JW. Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-?B Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells. PLoS One. 2013; 8(12):e82282. PMID: 24340014.
      Citations: 22     Fields:    Translation:HumansCells
    36. Zhang Y, Yang J, Cui X, Chen Y, Zhu VF, Hagan JP, Wang H, Yu X, Hodges SE, Fang J, Chiao PJ, Logsdon CD, Fisher WE, Brunicardi FC, Chen C, Yao Q, Fernandez-Zapico ME, Li M. A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth. EMBO Mol Med. 2013 Sep; 5(9):1322-34. PMID: 23857777.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    37. Chang Z, Li Z, Wang X, Kang Y, Yuan Y, Niu J, Wang H, Chatterjee D, Fleming JB, Li M, Abbruzzese JL, Chiao PJ. Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells. Clin Cancer Res. 2013 Feb 01; 19(3):549-59. PMID: 23340292.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    38. Zhang Y, Chen L, Yang J, Fleming JB, Chiao PJ, Logsdon CD, Li M. Study human pancreatic cancer in mice: how close are they? Biochim Biophys Acta. 2013 Jan; 1835(1):110-8. PMID: 23147198.
      Citations: 6     Fields:    Translation:HumansAnimals
    39. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-induced and PKCe monoubiquitylation-dependent NF-?B activation upregulates PKM2 expression and promotes tumorigenesis. Mol Cell. 2012 Dec 14; 48(5):771-84. PMID: 23123196.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    40. Fujioka S, Son K, Onda S, Schmidt C, Scrabas GM, Okamoto T, Fujita T, Chiao PJ, Yanaga K. Desensitization of NF?B for overcoming chemoresistance of pancreatic cancer cells to TNF-a or paclitaxel. Anticancer Res. 2012 Nov; 32(11):4813-21. PMID: 23155247.
      Citations: 9     Fields:    Translation:HumansCells
    41. Ling J, Kang Y, Zhao R, Xia Q, Lee DF, Chang Z, Li J, Peng B, Fleming JB, Wang H, Liu J, Lemischka IR, Hung MC, Chiao PJ. KrasG12D-induced IKK2/ß/NF-?B activation by IL-1a and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 2012 Jan 17; 21(1):105-20. PMID: 22264792.
      Citations: 253     Fields:    Translation:HumansAnimalsCells
    42. Hu Y, Lu W, Chen G, Wang P, Chen Z, Zhou Y, Ogasawara M, Trachootham D, Feng L, Pelicano H, Chiao PJ, Keating MJ, Garcia-Manero G, Huang P. K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis. Cell Res. 2012 Feb; 22(2):399-412. PMID: 21876558.
      Citations: 124     Fields:    Translation:HumansAnimalsCells
    43. Melisi D, Xia Q, Paradiso G, Ling J, Moccia T, Carbone C, Budillon A, Abbruzzese JL, Chiao PJ. Modulation of pancreatic cancer chemoresistance by inhibition of TAK1. J Natl Cancer Inst. 2011 Aug 03; 103(15):1190-204. PMID: 21743023.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    44. Carbone C, Moccia T, Zhu C, Paradiso G, Budillon A, Chiao PJ, Abbruzzese JL, Melisi D. Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype. Clin Cancer Res. 2011 Sep 01; 17(17):5822-32. PMID: 21737511.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    45. Chiao PJ, Ling J. Kras, Pten, NF-?B, and inflammation: dangerous liaisons. Cancer Discov. 2011 Jul; 1(2):103-5. PMID: 22586351.
      Citations: 8     Fields:    Translation:HumansAnimals
    46. Shim DJ, Yang L, Reed JG, Noebels JL, Chiao PJ, Zheng H. Disruption of the NF-?B/I?Ba Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons. Mol Neurodegener. 2011 Jun 10; 6:42. PMID: 21663635.
      Citations: 12     Fields:    
    47. Yang G, Xiao X, Rosen DG, Cheng X, Wu X, Chang B, Liu G, Xue F, Mercado-Uribe I, Chiao P, Du X, Liu J. The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer. Clin Cancer Res. 2011 Apr 15; 17(8):2181-94. PMID: 21339307.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    48. Peng B, Ling J, Lee AJ, Wang Z, Chang Z, Jin W, Kang Y, Zhang R, Shim D, Wang H, Fleming JB, Zheng H, Sun SC, Chiao PJ. Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15193-8. PMID: 20696914.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    49. Melisi D, Ossovskaya V, Zhu C, Rosa R, Ling J, Dougherty PM, Sherman BM, Abbruzzese JL, Chiao PJ. Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity. Clin Cancer Res. 2009 Oct 15; 15(20):6367-77. PMID: 19808866.
      Citations: 15     Fields:    Translation:AnimalsCells
    50. Son K, Fujioka S, Iida T, Furukawa K, Fujita T, Yamada H, Chiao PJ, Yanaga K. Doxycycline induces apoptosis in PANC-1 pancreatic cancer cells. Anticancer Res. 2009 Oct; 29(10):3995-4003. PMID: 19846942.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    51. Li Z, Chang Z, Chiao LJ, Kang Y, Xia Q, Zhu C, Fleming JB, Evans DB, Chiao PJ. TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation. Cancer Res. 2009 Oct 01; 69(19):7851-9. PMID: 19773448.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    52. Lu J, Guo H, Treekitkarnmongkol W, Li P, Zhang J, Shi B, Ling C, Zhou X, Chen T, Chiao PJ, Feng X, Seewaldt VL, Muller WJ, Sahin A, Hung MC, Yu D. 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell. 2009 Sep 08; 16(3):195-207. PMID: 19732720.
      Citations: 106     Fields:    Translation:HumansCells
    53. Uwagawa T, Chiao PJ, Gocho T, Hirohara S, Misawa T, Yanaga K. Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation. Anticancer Res. 2009 Aug; 29(8):3173-8. PMID: 19661331.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    54. Melisi D, Niu J, Chang Z, Xia Q, Peng B, Ishiyama S, Evans DB, Chiao PJ. Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB. Mol Cancer Res. 2009 May; 7(5):624-33. PMID: 19435817.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    55. Melisi D, Ishiyama S, Sclabas GM, Fleming JB, Xia Q, Tortora G, Abbruzzese JL, Chiao PJ. LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis. Mol Cancer Ther. 2008 Apr; 7(4):829-40. PMID: 18413796.
      Citations: 153     Fields:    Translation:HumansAnimalsCells
    56. Ricci MS, Kim SH, Ogi K, Plastaras JP, Ling J, Wang W, Jin Z, Liu YY, Dicker DT, Chiao PJ, Flaherty KT, Smith CD, El-Deiry WS. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer Cell. 2007 Jul; 12(1):66-80. PMID: 17613437.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    57. Xie X, Xia W, Li Z, Kuo HP, Liu Y, Li Z, Ding Q, Zhang S, Spohn B, Yang Y, Wei Y, Lang JY, Evans DB, Chiao PJ, Abbruzzese JL, Hung MC. Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. Cancer Cell. 2007 Jul; 12(1):52-65. PMID: 17613436.
      Citations: 40     Fields:    Translation:Animals
    58. Uwagawa T, Li Z, Chang Z, Xia Q, Peng B, Sclabas GM, Ishiyama S, Hung MC, Evans DB, Abbruzzese JL, Chiao PJ. Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. Cancer. 2007 May 15; 109(10):2142-53. PMID: 17410536.
      Citations: 15     Fields:    Translation:HumansCells
    59. Oida Y, Gopalan B, Miyahara R, Branch CD, Chiao P, Chada S, Ramesh R. Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation. Mol Cancer Ther. 2007 Apr; 6(4):1440-9. PMID: 17431123.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    60. Banerjee S, Zhang Y, Wang Z, Che M, Chiao PJ, Abbruzzese JL, Sarkar FH. In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. Int J Cancer. 2007 Feb 15; 120(4):906-17. PMID: 17131310.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    61. Melisi D, Chiao PJ. NF-kappa B as a target for cancer therapy. Expert Opin Ther Targets. 2007 Feb; 11(2):133-44. PMID: 17227230.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    62. Niu J, Chang Z, Peng B, Xia Q, Lu W, Huang P, Tsao MS, Chiao PJ. Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. J Biol Chem. 2007 Mar 02; 282(9):6001-11. PMID: 17200110.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    63. Xia D, Srinivas H, Ahn YH, Sethi G, Sheng X, Yung WK, Xia Q, Chiao PJ, Kim H, Brown PH, Wistuba II, Aggarwal BB, Kurie JM. Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway. J Biol Chem. 2007 Feb 09; 282(6):3507-19. PMID: 17158870.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    64. Kouvaraki MA, Korapati AL, Rassidakis GZ, Tian L, Zhang Q, Chiao P, Ho L, Evans DB, Claret FX. Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma. Cancer Res. 2006 Sep 01; 66(17):8581-9. PMID: 16951171.
      Citations: 26     Fields:    Translation:Humans
    65. Trachootham D, Zhou Y, Zhang H, Demizu Y, Chen Z, Pelicano H, Chiao PJ, Achanta G, Arlinghaus RB, Liu J, Huang P. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell. 2006 Sep; 10(3):241-52. PMID: 16959615.
      Citations: 434     Fields:    Translation:HumansAnimalsCells
    66. Choi W, Proctor L, Xia Q, Feng Y, Gerner EW, Chiao PJ, Hamilton SR, Zhang W. Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. Mol Carcinog. 2006 Sep; 45(9):685-93. PMID: 16637064.
      Citations: 4     Fields:    Translation:HumansCells
    67. Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE. Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. Angiogenesis. 2006; 9(2):101-10. PMID: 16871430.
      Citations: 21     Fields:    Translation:HumansCells
    68. Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Andtbacka RH, Dunner K, Pal A, Bornmann WG, Chiao PJ, Huang P, Xiong H, Abbruzzese JL, McConkey DJ. Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells. Cancer Res. 2006 Apr 01; 66(7):3773-81. PMID: 16585204.
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    69. Nawrocki ST, Carew JS, Dunner K, Boise LH, Chiao PJ, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Res. 2005 Dec 15; 65(24):11510-9. PMID: 16357160.
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    90. Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. Clin Cancer Res. 2002 Nov; 8(11):3628-38. PMID: 12429655.
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