XIN XU

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
ORCID ORCID Icon0000-0002-9485-8782 Additional info
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    Collapse Biography 
    Collapse awards and honors
    2017 - 2018Trainee Award, American association of immunologists (AAI)
    2016 - 2017Presentation awards, American Society of Gene & Cell Therapy (ASGCT)

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Heczey A, Xu X, Courtney AN, Tian G, Barragan GA, Guo L, Amador CM, Ghatwai N, Rathi P, Wood MS, Li Y, Zhang C, Demberg T, Di Pierro EJ, Sher AC, Zhang H, Mehta B, Thakkar SG, Grilley B, Wang T, Weiss BD, Montalbano A, Subramaniam M, Xu C, Sachar C, Wells DK, Dotti G, Metelitsa LS. Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results. Nat Med. 2023 Jun; 29(6):1379-1388. PMID: 37188782.
      Citations: 17     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    2. Tomolonis JA, Xu X, Dholakia KH, Zhang C, Guo L, Courtney AN, Wang S, Balzeau J, Barrag?n GA, Tian G, Di Pierro EJ, Metelitsa LS. Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-a triggers tumorigenic inflammation in neuroblastoma. J Immunother Cancer. 2023 03; 11(3). PMID: 36882225; PMCID: PMC10008329.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Ngai H, Barragan GA, Tian G, Balzeau JC, Zhang C, Courtney AN, Guo L, Xu X, Wood MS, Drabek JM, Demberg T, Sands CM, Chauvin-Fleurence CN, Di Pierro EJ, Rosen JM, Metelitsa LS. LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. Cancer Immunol Res. 2023 02 03; 11(2):171-183. PMID: 36484736; PMCID: PMC9898189.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    4. Heczey A, Courtney AN, Montalbano A, Robinson S, Liu K, Li M, Ghatwai N, Dakhova O, Liu B, Raveh-Sadka T, Chauvin-Fleurence CN, Xu X, Ngai H, Di Pierro EJ, Savoldo B, Dotti G, Metelitsa LS. Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis. Nat Med. 2020 11; 26(11):1686-1690. PMID: 33046868.
      Citations: 57     Fields:    Translation:HumansCellsCTClinical Trials
    5. Xu X, Huang W, Heczey A, Liu D, Guo L, Wood M, Jin J, Courtney AN, Liu B, Di Pierro EJ, Hicks J, Barragan GA, Ngai H, Chen Y, Savoldo B, Dotti G, Metelitsa LS. NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced In Vivo Persistence and Antitumor Activity against Neuroblastoma. Clin Cancer Res. 2019 12 01; 25(23):7126-7138. PMID: 31484667; PMCID: PMC6891170.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    6. Tian G, Courtney AN, Jena B, Heczey A, Liu D, Marinova E, Guo L, Xu X, Torikai H, Mo Q, Dotti G, Cooper LJ, Metelitsa LS. CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo. J Clin Invest. 2016 06 01; 126(6):2341-55. PMID: 27183388; PMCID: PMC4887157.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    7. Xu X, Metelitsa L, Hegazy WA, Hensel M. Correction for Hegazy et al., Evaluation of Salmonella enterica Type III Secretion System Effector Proteins as Carriers for Heterologous Vaccine Antigens. Infect Immun. 2015 Mar; 83(3):1225. PMID: 25681506; PMCID: PMC4333465.
      Citations:    Fields:    
    8. Xu X, Guo L, Gao X, Courtney AN, Kurbanov S, Liu D, Tian G, Manuel ER, Diamond DJ, Metelitsa LS, Hegazy WA, Hensel M. Effective cancer vaccine platform based on attenuated salmonella and a type III secretion system. Cancer Res. 2014 Nov 01; 74(21):6260-70. PMID: 25213323; PMCID: PMC4216746.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    9. Fan Y, Mao R, Yu Y, Liu S, Shi Z, Cheng J, Zhang H, An L, Zhao Y, Xu X, Chen Z, Kogiso M, Zhang D, Zhang H, Zhang P, Jung JU, Li X, Xu G, Yang J. USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase. J Exp Med. 2014 Feb 10; 211(2):313-28. PMID: 24493797; PMCID: PMC3920558.
      Citations: 88     Fields:    Translation:AnimalsCells
    10. Xu X, Metelitsa L, Hensel M, Hegazy WA. Evaluation of Salmonella enterica type III secretion system effector proteins as carriers for heterologous vaccine antigens. Infect Immun. 2012 Mar; 80(3):1193-202. PMID: 22252866; PMCID: PMC3294654.
      Citations: 17     Fields:    Translation:AnimalsCellsPHPublic Health
    11. Husseiny MI, Goldwich A, Hensel M, Xu X. Efficacy of intracellular activated promoters for generation of Salmonella-based vaccines. Infect Immun. 2010 Nov; 78(11):4828-38. PMID: 20732994; PMCID: PMC2976355.
      Citations: 13     Fields:    Translation:AnimalsCellsPHPublic Health
    12. Hensel M, Xu X. Systematic analysis of the SsrAB virulon of Salmonella enterica. Infect Immun. 2010 Jan; 78(1):49-58. PMID: 19858298; PMCID: PMC2798222.
      Citations: 33     Fields:    Translation:Cells
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