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KARIM A. ALKADHI

TitleProfessor
InstitutionUniversity of Houston College of Pharmacy
DepartmentPharmacological & Pharmaceutical Sciences
AddressHealth 2 4849 Calhoun Road, Room 5018
Houston, TX 77204-5037
Houston TX 77204-5037
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Alkadhi KA. Synaptic plasticity and cognitive ability in experimental adult-onset hypothyroidism. J Pharmacol Exp Ther. 2024 Mar 20. PMID: 38508752.
      Citations:    Fields:    
    2. Alzoubi K, Alkadhi K. Thyroidectomy and PTU-Induced Hypothyroidism: Effect of L-Thyroxine on Suppression of Spatial and Non-Spatial Memory Related Signaling Molecules. Curr Mol Pharmacol. 2023; 16(6):654-663. PMID: 36125841.
      Citations:    
    3. Atrooz F, Alkadhi KA, Salim S. Understanding stress: Insights from rodent models. Curr Res Neurobiol. 2021; 2:100013. PMID: 36246514; PMCID: PMC9559100.
      Citations: 9     
    4. Alkadhi KA. NMDA receptor-independent LTP in mammalian nervous system. Prog Neurobiol. 2021 05; 200:101986. PMID: 33400965.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    5. Alkadhi KA, Alzoubi KH. Comparison of Effects of Spatial and Non-Spatial Memory Acquisition on the CaMKII Pathway During Hypothyroidism and Nicotine Treatment. Mol Neurobiol. 2020 Apr; 57(4):1930-1937. PMID: 31900862.
      Citations: 1     Fields:    Translation:AnimalsCells
    6. Alkadhi KA. Cellular and Molecular Differences Between Area CA1 and the Dentate Gyrus of the Hippocampus. Mol Neurobiol. 2019 Sep; 56(9):6566-6580. PMID: 30874972.
      Citations: 16     Fields:    Translation:HumansAnimals
    7. Alkadhi KA, Dao AT. Effect of Exercise and A? Protein Infusion on Long-Term Memory-Related Signaling Molecules in Hippocampal Areas. Mol Neurobiol. 2019 Jul; 56(7):4980-4987. PMID: 30426389.
      Citations: 1     Fields:    Translation:Animals
    8. Alkadhi KA. Neuroprotective Effects of Nicotine on Hippocampal Long-Term Potentiation in Brain Disorders. J Pharmacol Exp Ther. 2018 09; 366(3):498-508. PMID: 29914875.
      Citations: 5     Fields:    Translation:HumansAnimals
    9. Alkadhi KA. Delayed effects of combined stress and A? infusion on L-LTP of the dentate gyrus: Prevention by nicotine. Neurosci Lett. 2018 08 24; 682:10-15. PMID: 29883681.
      Citations: 1     Fields:    Translation:Animals
    10. Dao AT, Zagaar MA, Levine AT, Alkadhi KA. Correction to: Comparison of the Effect of Exercise on Late-Phase LTP of the Dentate Gyrus and CA1 of Alzheimer's Disease Model. Mol Neurobiol. 2018 01; 55(1):903. PMID: 28983832.
      Citations:    Fields:    
    11. Dao AT, Zagaar MA, Alkadhi KA. Correction to: Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer's Disease. Mol Neurobiol. 2018 01; 55(1):901. PMID: 28983833.
      Citations:    Fields:    
    12. Zagaar MA, Dao AT, Alhaider IA, Alkadhi KA. Correction to: Prevention by Regular Exercise of Acute Sleep Deprivation-Induced Impairment of Late Phase LTP and Related Signaling Molecules in the Dentate Gyrus. Mol Neurobiol. 2018 01; 55(1):902. PMID: 28983834.
      Citations: 2     Fields:    
    13. Zagaar M, Dao A, Alhaider I, Alkadhi K. Corrigendum to "Regular treadmill exercise prevents sleep deprivation-induced disruption of synaptic plasticity and associated signaling cascade in the dentate gyrus" [Mol. Cell Neurosci. 56 (2013 Sep) 375-83]. Mol Cell Neurosci. 2018 04; 88:353. PMID: 29276073.
      Citations:    Fields:    
    14. Alkadhi KA, Dao AT. Exercise decreases BACE and APP levels in the hippocampus of a rat model of Alzheimer's disease. Mol Cell Neurosci. 2018 01; 86:25-29. PMID: 29128320.
      Citations: 16     Fields:    Translation:Animals
    15. Alkadhi KA. Exercise as a Positive Modulator of Brain Function. Mol Neurobiol. 2018 Apr; 55(4):3112-3130. PMID: 28466271.
      Citations: 20     Fields:    Translation:HumansAnimals
    16. Alkadhi KA, Alhaider IA. Caffeine and REM sleep deprivation: Effect on basal levels of signaling molecules in area CA1. Mol Cell Neurosci. 2016 Mar; 71:125-31. PMID: 26767416.
      Citations: 8     Fields:    Translation:AnimalsCells
    17. Dao AT, Zagaar MA, Levine AT, Alkadhi KA. Comparison of the Effect of Exercise on Late-Phase LTP of the Dentate Gyrus and CA1 of Alzheimer's Disease Model. Mol Neurobiol. 2016 12; 53(10):6859-6868. PMID: 26660327.
      Citations: 10     Fields:    Translation:AnimalsCells
    18. Alhaider IA, Alkadhi KA. Caffeine treatment prevents rapid eye movement sleep deprivation-induced impairment of late-phase long-term potentiation in the dentate gyrus. Eur J Neurosci. 2015 Nov; 42(10):2843-50. PMID: 26449851.
      Citations: 3     Fields:    Translation:AnimalsCells
    19. Zagaar MA, Dao AT, Alhaider IA, Alkadhi KA. Prevention by Regular Exercise of Acute Sleep Deprivation-Induced Impairment of Late Phase LTP and Related Signaling Molecules in the Dentate Gyrus. Mol Neurobiol. 2016 07; 53(5):2900-2910. PMID: 25902862.
      Citations: 10     Fields:    Translation:AnimalsCells
    20. Dao AT, Zagaar MA, Alkadhi KA. Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer's Disease. Mol Neurobiol. 2015 Dec; 52(3):1067-1076. PMID: 25288155.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    21. Alkadhi KA, Tran TT. Chronic psychosocial stress impairs early LTP but not late LTP in the dentate gyrus of at-risk rat model of Alzheimer's disease. Brain Res. 2014 Nov 07; 1588:150-8. PMID: 25219483.
      Citations: 1     Fields:    Translation:Animals
    22. Alkadhi KA, Tran TT. Chronic Stress Decreases Basal Levels of Memory-Related Signaling Molecules in Area CA1 of At-Risk (Subclinical) Model of Alzheimer's Disease. Mol Neurobiol. 2015 Aug; 52(1):93-100. PMID: 25112676.
      Citations: 2     Fields:    Translation:AnimalsCells
    23. Patki G, Li L, Allam F, Solanki N, Dao AT, Alkadhi K, Salim S. Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder. Physiol Behav. 2014 May 10; 130:47-53. PMID: 24657739; PMCID: PMC4318362.
      Citations: 49     Fields:    Translation:Animals
    24. Alzoubi KH, Alkadhi KA. Chronic nicotine treatment reverses hypothyroidism-induced impairment of L-LTP induction phase: critical role of CREB. Mol Neurobiol. 2014 Jun; 49(3):1245-55. PMID: 24277525.
      Citations: 3     Fields:    Translation:Animals
    25. Dao AT, Zagaar MA, Salim S, Eriksen JL, Alkadhi KA. Regular exercise prevents non-cognitive disturbances in a rat model of Alzheimer's disease. Int J Neuropsychopharmacol. 2014 Apr; 17(4):593-602. PMID: 24229510; PMCID: PMC4097602.
      Citations: 14     Fields:    Translation:AnimalsCells
    26. Alzoubi KH, Alkadhi KA. Levothyroxin replacement therapy restores hypothyroidism induced impairment of L-LTP induction: critical role of CREB. Brain Res Bull. 2014 Jan; 100:29-37. PMID: 24216002.
      Citations: 7     Fields:    Translation:AnimalsCells
    27. Patki G, Allam FH, Atrooz F, Dao AT, Solanki N, Chugh G, Asghar M, Jafri F, Bohat R, Alkadhi KA, Salim S. Grape powder intake prevents ovariectomy-induced anxiety-like behavior, memory impairment and high blood pressure in female Wistar rats. PLoS One. 2013; 8(9):e74522. PMID: 24040270; PMCID: PMC3767647.
      Citations: 27     Fields:    Translation:Animals
    28. Zagaar M, Dao A, Alhaider I, Alkadhi K. Regular treadmill exercise prevents sleep deprivation-induced disruption of synaptic plasticity and associated signaling cascade in the dentate gyrus. Mol Cell Neurosci. 2013 Sep; 56:375-83. PMID: 23911794.
      Citations: 14     Fields:    Translation:AnimalsCells
    29. Chugh G, Asghar M, Patki G, Bohat R, Jafri F, Allam F, Dao AT, Mowrey C, Alkadhi K, Salim S. A high-salt diet further impairs age-associated declines in cognitive, behavioral, and cardiovascular functions in male Fischer brown Norway rats. J Nutr. 2013 Sep; 143(9):1406-13. PMID: 23864508; PMCID: PMC3743272.
      Citations: 13     Fields:    Translation:Animals
    30. Alzoubi KH, Khabour OF, Alhaidar IA, Aleisa AM, Alkadhi KA. Diabetes impairs synaptic plasticity in the superior cervical ganglion: possible role for BDNF and oxidative stress. J Mol Neurosci. 2013 Nov; 51(3):763-70. PMID: 23832486.
      Citations: 2     Fields:    Translation:Animals
    31. Dao AT, Zagaar MA, Levine AT, Salim S, Eriksen JL, Alkadhi KA. Treadmill exercise prevents learning and memory impairment in Alzheimer's disease-like pathology. Curr Alzheimer Res. 2013 06; 10(5):507-15. PMID: 23627709; PMCID: PMC4004077.
      Citations: 37     Fields:    Translation:AnimalsCells
    32. Zagaar M, Dao A, Levine A, Alhaider I, Alkadhi K. Regular exercise prevents sleep deprivation associated impairment of long-term memory and synaptic plasticity in the CA1 area of the hippocampus. Sleep. 2013 May 01; 36(5):751-61. PMID: 23633758; PMCID: PMC3624830.
      Citations: 26     Fields:    Translation:AnimalsCells
    33. Alkadhi K, Zagaar M, Alhaider I, Salim S, Aleisa A. Neurobiological consequences of sleep deprivation. Curr Neuropharmacol. 2013 05; 11(3):231-49. PMID: 24179461; PMCID: PMC3648777.
      Citations: 30     Fields:    
    34. Allam F, Dao AT, Chugh G, Bohat R, Jafri F, Patki G, Mowrey C, Asghar M, Alkadhi KA, Salim S. Grape powder supplementation prevents oxidative stress-induced anxiety-like behavior, memory impairment, and high blood pressure in rats. J Nutr. 2013 Jun; 143(6):835-42. PMID: 23596160; PMCID: PMC3652881.
      Citations: 34     Fields:    Translation:Animals
    35. Alzoubi KH, Srivareerat M, Tran TT, Alkadhi KA. Role of a7- and a4?2-nAChRs in the neuroprotective effect of nicotine in stress-induced impairment of hippocampus-dependent memory. Int J Neuropsychopharmacol. 2013 Jun; 16(5):1105-13. PMID: 23067572.
      Citations: 8     Fields:    Translation:Animals
    36. Alzoubi KH, Abdul-Razzak KK, Khabour OF, Al-Tuweiq GM, Alzubi MA, Alkadhi KA. Caffeine prevents cognitive impairment induced by chronic psychosocial stress and/or high fat-high carbohydrate diet. Behav Brain Res. 2013 Jan 15; 237:7-14. PMID: 23000531.
      Citations: 16     Fields:    Translation:Animals
    37. Alzoubi KH, Srivareerat M, Aleisa AM, Alkadhi KA. Chronic caffeine treatment prevents stress-induced LTP impairment: the critical role of phosphorylated CaMKII and BDNF. J Mol Neurosci. 2013 Jan; 49(1):11-20. PMID: 22706686.
      Citations: 10     Fields:    Translation:AnimalsCells
    38. Zagaar M, Alhaider I, Dao A, Levine A, Alkarawi A, Alzubaidy M, Alkadhi K. The beneficial effects of regular exercise on cognition in REM sleep deprivation: behavioral, electrophysiological and molecular evidence. Neurobiol Dis. 2012 Mar; 45(3):1153-62. PMID: 22227452.
      Citations: 27     Fields:    Translation:Animals
    39. Alkadhi K, Eriksen J. The complex and multifactorial nature of Alzheimer's disease. Curr Neuropharmacol. 2011 Dec; 9(4):586. PMID: 22654718; PMCID: PMC3263454.
      Citations: 11     Fields:    
    40. Alkadhi KA. Chronic stress and Alzheimer's disease-like pathogenesis in a rat model: prevention by nicotine. Curr Neuropharmacol. 2011 Dec; 9(4):587-97. PMID: 22654719; PMCID: PMC3263455.
      Citations: 6     Fields:    
    41. Alkadhi KA, Alzoubi KH, Srivareerat M, Tran TT. Chronic psychosocial stress exacerbates impairment of synaptic plasticity in ?-amyloid rat model of Alzheimer's disease: prevention by nicotine. Curr Alzheimer Res. 2011 Nov; 8(7):718-31. PMID: 21453245.
      Citations: 12     Fields:    Translation:Animals
    42. Tran TT, Srivareerat M, Alhaider IA, Alkadhi KA. Chronic psychosocial stress enhances long-term depression in a subthreshold amyloid-beta rat model of Alzheimer's disease. J Neurochem. 2011 Oct; 119(2):408-16. PMID: 21854392.
      Citations: 8     Fields:    Translation:AnimalsCells
    43. Aleisa AM, Alzoubi KH, Alkadhi KA. Post-learning REM sleep deprivation impairs long-term memory: reversal by acute nicotine treatment. Neurosci Lett. 2011 Jul 15; 499(1):28-31. PMID: 21624432.
      Citations: 22     Fields:    Translation:Animals
    44. Vollert C, Zagaar M, Hovatta I, Taneja M, Vu A, Dao A, Levine A, Alkadhi K, Salim S. Exercise prevents sleep deprivation-associated anxiety-like behavior in rats: potential role of oxidative stress mechanisms. Behav Brain Res. 2011 Oct 31; 224(2):233-40. PMID: 21621560.
      Citations: 72     Fields:    Translation:Animals
    45. Zoladz PR, Park CR, Halonen JD, Salim S, Alzoubi KH, Srivareerat M, Fleshner M, Alkadhi KA, Diamond DM. Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia. Hippocampus. 2012 Mar; 22(3):577-89. PMID: 21538655.
      Citations: 20     Fields:    Translation:AnimalsCells
    46. Alkadhi KA, Alzoubi KH, Srivareerat M, Tran TT. Elevation of BACE in an A? rat model of Alzheimer's disease: exacerbation by chronic stress and prevention by nicotine. Int J Neuropsychopharmacol. 2012 Mar; 15(2):223-33. PMID: 21356140.
      Citations: 5     Fields:    Translation:Animals
    47. Alkadhi KA, Srivareerat M, Tran TT. Intensification of long-term memory deficit by chronic stress and prevention by nicotine in a rat model of Alzheimer's disease. Mol Cell Neurosci. 2010 Nov; 45(3):289-96. PMID: 20624465.
      Citations: 16     Fields:    Translation:Animals
    48. Aleisa AM, Helal G, Alhaider IA, Alzoubi KH, Srivareerat M, Tran TT, Al-Rejaie SS, Alkadhi KA. Acute nicotine treatment prevents REM sleep deprivation-induced learning and memory impairment in rat. Hippocampus. 2011 Aug; 21(8):899-909. PMID: 20865738.
      Citations: 34     Fields:    Translation:Animals
    49. Tran TT, Srivareerat M, Alkadhi KA. Chronic psychosocial stress accelerates impairment of long-term memory and late-phase long-term potentiation in an at-risk model of Alzheimer's disease. Hippocampus. 2011 Jul; 21(7):724-32. PMID: 20865724.
      Citations: 12     Fields:    Translation:Animals
    50. Alhaider IA, Aleisa AM, Tran TT, Alkadhi KA. Caffeine prevents sleep loss-induced deficits in long-term potentiation and related signaling molecules in the dentate gyrus. Eur J Neurosci. 2010 Apr; 31(8):1368-76. PMID: 20384774.
      Citations: 24     Fields:    Translation:AnimalsCells
    51. Alhaider IA, Aleisa AM, Tran TT, Alzoubi KH, Alkadhi KA. Chronic caffeine treatment prevents sleep deprivation-induced impairment of cognitive function and synaptic plasticity. Sleep. 2010 Apr; 33(4):437-44. PMID: 20394312; PMCID: PMC2849782.
      Citations: 44     Fields:    Translation:AnimalsCells
    52. Tran TT, Srivareerat M, Alkadhi KA. Chronic psychosocial stress triggers cognitive impairment in a novel at-risk model of Alzheimer's disease. Neurobiol Dis. 2010 Mar; 37(3):756-63. PMID: 20044001.
      Citations: 23     Fields:    Translation:AnimalsCells
    53. Alzoubi KH, Abdul-Razzak KK, Khabour OF, Al-Tuweiq GM, Alzubi MA, Alkadhi KA. Adverse effect of combination of chronic psychosocial stress and high fat diet on hippocampus-dependent memory in rats. Behav Brain Res. 2009 Dec 01; 204(1):117-23. PMID: 19482049.
      Citations: 22     Fields:    Translation:Animals
    54. Srivareerat M, Tran TT, Salim S, Aleisa AM, Alkadhi KA. Chronic nicotine restores normal A? levels and prevents short-term memory and E-LTP impairment in A? rat model of Alzheimer's disease. Neurobiol Aging. 2011 May; 32(5):834-44. PMID: 19464074.
      Citations: 48     Fields:    Translation:AnimalsCells
    55. Alzoubi KH, Gerges NZ, Aleisa AM, Alkadhi KA. Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: Behavioral, electrophysiological, and molecular studies. Hippocampus. 2009 Jan; 19(1):66-78. PMID: 18680156.
      Citations: 54     Fields:    Translation:AnimalsCells
    56. Alzoubi KH, Alkadhi KA. Calmodulin and guanylyl cyclase inhibitors block the in vivo expression of gLTP in sympathetic ganglia from chronically stressed rats. Neurosci Res. 2009 Feb; 63(2):95-9. PMID: 19038294.
      Citations:    Fields:    Translation:Animals
    57. Srivareerat M, Tran TT, Alzoubi KH, Alkadhi KA. Chronic psychosocial stress exacerbates impairment of cognition and long-term potentiation in beta-amyloid rat model of Alzheimer's disease. Biol Psychiatry. 2009 Jun 01; 65(11):918-26. PMID: 18849021.
      Citations: 46     Fields:    Translation:AnimalsCells
    58. Alkadhi KA. Rhythmic discharge induced by temperature variation and drugs in isolated sympathetic ganglia. Clin Exp Hypertens. 2008 Oct; 30(7):497-510. PMID: 18855254.
      Citations:    Fields:    Translation:Animals
    59. Alkadhi KA, Al-Hijailan RS, Alzoubi KH. Long-term depression in the superior cervical ganglion of the rat. Brain Res. 2008 Oct 09; 1234:25-31. PMID: 18718451.
      Citations: 3     Fields:    Translation:AnimalsCells
    60. Alzoubi KH, Aleisa AM, Alkadhi KA. In vivo expression of ganglionic long-term potentiation in superior cervical ganglia from hypertensive aged rats. Neurobiol Aging. 2010 May; 31(5):805-12. PMID: 18649973.
      Citations: 5     Fields:    Translation:AnimalsCells
    61. Alzoubi KH, Aleisa AM, Alkadhi KA. Effect of chronic stress or nicotine on hypothyroidism-induced enhancement of LTD: electrophysiological and molecular studies. Neurobiol Dis. 2008 Oct; 32(1):81-7. PMID: 18638553.
      Citations: 5     Fields:    Translation:Animals
    62. Alzoubi KH, Aleisa AM, Alkadhi KA. Expression of gLTP in sympathetic ganglia of obese Zucker rats in vivo: molecular evidence. J Mol Neurosci. 2008 Jul; 35(3):297-306. PMID: 18563301.
      Citations: 1     Fields:    Translation:AnimalsCells
    63. Alzoubi KH, Aleisa AM, Alkadhi KA. Expression of gLTP in sympathetic ganglia from stress-hypertensive rats: molecular evidence. J Mol Neurosci. 2008 Jun; 35(2):201-9. PMID: 18386186.
      Citations: 2     Fields:    Translation:Animals
    64. Alzoubi KH, Aleisa AM, Alkadhi KA. The sliding threshold of modification hypothesis: application to the effect of hypothyroidism or chronic psychosocial stress and nicotine on synaptic plasticity. Neurosci Lett. 2008 Jan 17; 430(3):203-6. PMID: 18063475.
      Citations: 3     Fields:    Translation:AnimalsCells
    65. Alzoubi KH, Aleisa AM, Alkadhi KA. Adult-onset hypothyroidism facilitates and enhances LTD: reversal by chronic nicotine treatment. Neurobiol Dis. 2007 Apr; 26(1):264-72. PMID: 17331737.
      Citations: 9     Fields:    Translation:Animals
    66. Alzoubi KH, Aleisa AM, Alkadhi KA. Nicotine prevents disruption of the late phase LTP-related molecular cascade in adult-onset hypothyroidism. Hippocampus. 2007; 17(8):654-64. PMID: 17523180.
      Citations: 8     Fields:    Translation:Animals
    67. Alzoubi KH, Aleisa AM, Gerges NZ, Alkadhi KA. Nicotine reverses adult-onset hypothyroidism-induced impairment of learning and memory: Behavioral and electrophysiological studies. J Neurosci Res. 2006 Oct; 84(5):944-53. PMID: 16902999.
      Citations: 16     Fields:    Translation:Animals
    68. Alzoubi KH, Alkadhi KA. A critical role of CREB in the impairment of late-phase LTP by adult onset hypothyroidism. Exp Neurol. 2007 Jan; 203(1):63-71. PMID: 16952356.
      Citations: 12     Fields:    Translation:AnimalsCells
    69. Aleisa AM, Alzoubi KH, Alkadhi KA. Chronic but not acute nicotine treatment reverses stress-induced impairment of LTP in anesthetized rats. Brain Res. 2006 Jun 30; 1097(1):78-84. PMID: 16725127.
      Citations: 4     Fields:    Translation:Animals
    70. Aleisa AM, Alzoubi KH, Gerges NZ, Alkadhi KA. Chronic psychosocial stress-induced impairment of hippocampal LTP: possible role of BDNF. Neurobiol Dis. 2006 Jun; 22(3):453-62. PMID: 16530419.
      Citations: 25     Fields:    Translation:Animals
    71. Aleisa AM, Alzoubi KH, Alkadhi KA. Nicotine prevents stress-induced enhancement of long-term depression in hippocampal area CA1: electrophysiological and molecular studies. J Neurosci Res. 2006 Feb 01; 83(2):309-17. PMID: 16307449.
      Citations: 8     Fields:    Translation:Animals
    72. Alzoubi KH, Aleisa AM, Alkadhi KA. Molecular studies on the protective effect of nicotine in adult-onset hypothyroidism-induced impairment of long-term potentiation. Hippocampus. 2006; 16(10):861-74. PMID: 16897721.
      Citations: 14     Fields:    Translation:AnimalsCells
    73. Alzoubi KH, Gerges NZ, Alkadhi KA. Levothyroxin restores hypothyroidism-induced impairment of LTP of hippocampal CA1: electrophysiological and molecular studies. Exp Neurol. 2005 Oct; 195(2):330-41. PMID: 16004982.
      Citations: 24     Fields:    Translation:AnimalsCells
    74. Aleisa AM, Alzoubi KH, Gerges NZ, Alkadhi KA. Nicotine blocks stress-induced impairment of spatial memory and long-term potentiation of the hippocampal CA1 region. Int J Neuropsychopharmacol. 2006 Aug; 9(4):417-26. PMID: 16316479.
      Citations: 21     Fields:    Translation:Animals
    75. Alkadhi KA, Alzoubi KH, Aleisa AM, Tanner FL, Nimer AS. Psychosocial stress-induced hypertension results from in vivo expression of long-term potentiation in rat sympathetic ganglia. Neurobiol Dis. 2005 Dec; 20(3):849-57. PMID: 16005635.
      Citations: 16     Fields:    Translation:AnimalsCells
    76. Gerges NZ, Alzoubi KH, Alkadhi KA. Role of phosphorylated CaMKII and calcineurin in the differential effect of hypothyroidism on LTP of CA1 and dentate gyrus. Hippocampus. 2005; 15(4):480-90. PMID: 15714506.
      Citations: 15     Fields:    Translation:AnimalsCells
    77. Alzoubi KH, Aleisa AM, Alkadhi KA. Impairment of long-term potentiation in the CA1, but not dentate gyrus, of the hippocampus in Obese Zucker rats: role of calcineurin and phosphorylated CaMKII. J Mol Neurosci. 2005; 27(3):337-46. PMID: 16280604.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    78. Gerges NZ, Alzoubi KH, Park CR, Diamond DM, Alkadhi KA. Adverse effect of the combination of hypothyroidism and chronic psychosocial stress on hippocampus-dependent memory in rats. Behav Brain Res. 2004 Nov 05; 155(1):77-84. PMID: 15325781.
      Citations: 37     Fields:    Translation:Animals
    79. Alzoubi KH, Bedawi AS, Aleisa AM, Alkadhi KA. Hypothyroidism impairs long-term potentiation in sympathetic ganglia: electrophysiologic and molecular studies. J Neurosci Res. 2004 Nov 01; 78(3):393-402. PMID: 15389831.
      Citations: 5     Fields:    Translation:Animals
    80. Otoom SA, Alkadhi KA, Daoud AS. Guanosine 3`,5`-monophosphate is not a marker of the proepileptic activity of valproic acid in hippocampal brain tissues. Neurosciences (Riyadh). 2004 Jul; 9(3):176-9. PMID: 23377423.
      Citations:    Fields:    
    81. Gerges NZ, Aleisa AM, Schwarz LA, Alkadhi KA. Reduced basal CaMKII levels in hippocampal CA1 region: possible cause of stress-induced impairment of LTP in chronically stressed rats. Hippocampus. 2004; 14(3):402-10. PMID: 15132438.
      Citations: 25     Fields:    Translation:AnimalsCells
    82. Gerges NZ, Alkadhi KA. Hypothyroidism impairs late LTP in CA1 region but not in dentate gyrus of the intact rat hippocampus: MAPK involvement. Hippocampus. 2004; 14(1):40-5. PMID: 15058481.
      Citations: 28     Fields:    Translation:AnimalsCells
    83. Gerges NZ, Aleisa AM, Alkadhi KA. Impaired long-term potentiation in obese zucker rats: possible involvement of presynaptic mechanism. Neuroscience. 2003; 120(2):535-9. PMID: 12890522.
      Citations: 41     Fields:    Translation:AnimalsCells
    84. Gerges NZ, Aleisa AM, Schwarz LA, Alkadhi KA. Chronic psychosocial stress decreases calcineurin in the dentate gyrus: a possible mechanism for preservation of early ltp. Neuroscience. 2003; 117(4):869-74. PMID: 12654339.
      Citations: 10     Fields:    Translation:AnimalsCells
    85. Gerges NZ, Aleisa AM, Alhaider AA, Alkadhi KA. Reduction of elevated arterial blood pressure in obese Zucker rats by inhibition of ganglionic long-term potentiation. Neuropharmacology. 2002 Dec; 43(7):1070-6. PMID: 12504912.
      Citations: 10     Fields:    Translation:Animals
    86. Gerges NZ, Stringer JL, Alkadhi KA. Combination of hypothyroidism and stress abolishes early LTP in the CA1 but not dentate gyrus of hippocampus of adult rats. Brain Res. 2001 Dec 20; 922(2):250-60. PMID: 11743957.
      Citations: 40     Fields:    Translation:AnimalsCells
    87. Alkadhi KA, Otoom SA, Tanner FL, Sockwell D, Hogan YH. Inhibition of ganglionic long-term potentiation decreases blood pressure in spontaneously hypertensive rats. Exp Biol Med (Maywood). 2001 Dec; 226(11):1024-30. PMID: 11743138.
      Citations: 8     Fields:    Translation:Animals
    88. Alkadhi KA, Al-Hijailan RS, Malik K, Hogan YH. Retrograde carbon monoxide is required for induction of long-term potentiation in rat superior cervical ganglion. J Neurosci. 2001 May 15; 21(10):3515-20. PMID: 11331380; PMCID: PMC6762490.
      Citations: 11     Fields:    Translation:AnimalsCells
    89. Otoom SA, Alkadhi KA. Action of carbamazepine on epileptiform activity of the verartidine model in CA1 neurons. Brain Res. 2000 Dec 08; 885(2):289-94. PMID: 11102583.
      Citations: 1     Fields:    Translation:Animals
    90. Otoom SA, Alkadhi KA. Epileptiform activity of veratridine model in rat brain slices: effects of antiepileptic drugs. Epilepsy Res. 2000 Feb; 38(2-3):161-70. PMID: 10642044.
      Citations: 2     Fields:    Translation:AnimalsCells
    91. Otoom SA, Alkadhi KA. Valproic acid intensifies epileptiform activity in the hippocampal pyramidal neurons. Neurosci Res. 1999 Dec 30; 35(4):299-307. PMID: 10617321.
      Citations: 2     Fields:    Translation:AnimalsCells
    92. Altememi GF, Alkadhi KA. Nitric oxide is required for the maintenance but not initiation of ganglionic long-term potentiation. Neuroscience. 1999; 94(3):897-902. PMID: 10579581.
      Citations: 4     Fields:    Translation:AnimalsCells
    93. Hogan YH, Hawkins R, Alkadhi KA. Adenosine A1 receptor activation inhibits LTP in sympathetic ganglia. Brain Res. 1998 Oct 05; 807(1-2):19-28. PMID: 9756986.
      Citations: 5     Fields:    Translation:Animals
    94. Otoom S, Tian LM, Alkadhi KA. Veratridine-treated brain slices: a cellular model for epileptiform activity. Brain Res. 1998 Apr 06; 789(1):150-6. PMID: 9602103.
      Citations: 1     Fields:    Translation:AnimalsCells
    95. Hogan YH, Florent G, Hussain T, Alkadhi KA. Cyclic AMP antagonizes adenosine-induced inhibition of ganglionic transmission. Brain Res. 1998 Mar 23; 787(2):242-7. PMID: 9518635.
      Citations: 1     Fields:    Translation:AnimalsCells
    96. Salgado-Commissariat D, Alkadhi KA. Serotonin inhibits epileptiform discharge by activation of 5-HT1A receptors in CA1 pyramidal neurons. Neuropharmacology. 1997 Nov-Dec; 36(11-12):1705-12. PMID: 9517442.
      Citations: 8     Fields:    Translation:AnimalsCells
    97. Alkadhi KA, Altememi GF. Nitric oxide mediates long-term potentiation in rat superior cervical ganglion. Brain Res. 1997 Apr 11; 753(2):315-7. PMID: 9125417.
      Citations: 3     Fields:    Translation:Animals
    98. Salgado-Commissariat D, Alkadhi KA. Effects of serotonin on induced epileptiform activity in CA1 pyramidal neurons of genetically epilepsy prone rats. Brain Res. 1996 Dec 16; 743(1-2):212-6. PMID: 9017248.
      Citations: 2     Fields:    Translation:AnimalsCells
    99. Alkadhi KA, Salgado-Commissariat D, Hogan YH, Akpaudo SB. Induction and maintenance of ganglionic long-term potentiation require activation of 5-hydroxytryptamine (5-HT3) receptors. J Physiol. 1996 Oct 15; 496 ( Pt 2):479-89. PMID: 8910231; PMCID: PMC1160892.
      Citations: 13     Fields:    Translation:AnimalsCells
    100. Alkadhi KA, Tian LM. Veratridine-enhanced persistent sodium current induces bursting in CA1 pyramidal neurons. Neuroscience. 1996 Apr; 71(3):625-32. PMID: 8867036.
      Citations: 7     Fields:    Translation:AnimalsCells
    101. Tian LM, Otoom S, Alkadhi KA. Endogenous bursting due to altered sodium channel function in rat hippocampal CA1 neurons. Brain Res. 1995 May 22; 680(1-2):164-72. PMID: 7663974.
      Citations: 3     Fields:    Translation:AnimalsCells
    102. Salgado D, Alkadhi KA. Inhibition of epileptiform activity by serotonin in rat CA1 neurons. Brain Res. 1995 Jan 16; 669(2):176-82. PMID: 7712172.
      Citations: 12     Fields:    Translation:AnimalsCells
    103. Tian LM, Alkadhi KA. Valproic acid inhibits the depolarizing rectification in neurons of rat amygdala. Neuropharmacology. 1994 Oct; 33(10):1131-8. PMID: 7862248.
      Citations: 5     Fields:    Translation:AnimalsCells
    104. Salgado D, Shek EW, Alkadhi KA. Effects of ATP-sensitive K(+)-channel activators on transmitter release parameters at the frog neuromuscular junction. Brain Res. 1993 Apr 23; 609(1-2):307-12. PMID: 8099524.
      Citations: 1     Fields:    Translation:AnimalsCells
    105. Alkadhi KA, Salgado D, Davis CA, Udofia EI. Effects of gamma-aminobutyric acid on the compound action potential of the rat superior cervical ganglion. Arch Int Pharmacodyn Ther. 1993 Mar-Apr; 322:66-79. PMID: 8215719.
      Citations:    Fields:    Translation:AnimalsCells
    106. Alkadhi KA, Hogan YH. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on ganglionic transmission. J Auton Pharmacol. 1992 Feb; 12(1):15-23. PMID: 1313036.
      Citations: 1     Fields:    Translation:AnimalsCells
    107. Alkadhi KA, Simples JE. Effects of inorganic potassium channel blockers on calcium requirement of transmission in a sympathetic ganglion. J Auton Nerv Syst. 1991 Jun 15; 34(2-3):221-9. PMID: 1655860.
      Citations: 1     Fields:    Translation:AnimalsCells
    108. Alkadhi KA, Bassey EI, Hogan YH. A comparative study of the actions of histamine H2 receptor antagonists on transmission in the isolated superior cervical ganglion of the rat. Neuropharmacology. 1990 Mar; 29(3):285-90. PMID: 1970132.
      Citations:    Fields:    Translation:AnimalsCells
    109. Alkadhi KA. Giant miniature end-plate potentials at the untreated and emetine-treated frog neuromuscular junction. J Physiol. 1989 May; 412:475-91. PMID: 2600842; PMCID: PMC1190587.
      Citations: 6     Fields:    Translation:AnimalsCells
    110. Alkadhi KA, Hogan YH. Effect of calcium on synaptic facilitation by potassium channel blockers in superior cervical ganglion of rat. Neuropharmacology. 1989 Jan; 28(1):75-81. PMID: 2538769.
      Citations: 1     Fields:    Translation:AnimalsCells
    111. Alkadhi KA. Emetine increases giant miniature endplate potential population at the frog neuromuscular junction. Brain Res. 1988 May 03; 447(2):293-8. PMID: 3260532.
      Citations: 2     Fields:    Translation:AnimalsCells
    112. Alkadhi KA, Sabouni MH, Hogan YH, Jandhyala BS. Effects of felodipine and verapamil on transmission in the isolated superior cervical ganglion of the rat. Arch Int Pharmacodyn Ther. 1987 Jul; 288(1):50-8. PMID: 2821941.
      Citations:    Fields:    Translation:AnimalsCells
    113. Alkadhi KA. Effects of emetine and dehydroemetine at the frog neuromuscular junction. Eur J Pharmacol. 1987 Jun 19; 138(2):257-64. PMID: 2887439.
      Citations: 2     Fields:    Translation:AnimalsCells
    114. Sabouni MH, Alkadhi KA, Lokhandwala MF. Effect of dopamine receptor activation on ganglionic transmission and cyclic AMP levels in the stellate ganglia and renal arteries of the dog. J Pharmacol Exp Ther. 1987 Jan; 240(1):93-8. PMID: 2879905.
      Citations: 1     Fields:    Translation:AnimalsCells
    115. Alkadhi KA, Sabouni MH, Ansari AF, Lokhandwala MF. Activation of DA1 receptors by dopamine or fenoldopam increases cyclic AMP levels in the renal artery but not in the superior cervical ganglion of the rat. J Pharmacol Exp Ther. 1986 Aug; 238(2):547-53. PMID: 2874213.
      Citations: 5     Fields:    Translation:AnimalsCells
    116. Cates LA, Li VS, Basrur JP, Alkadhi KA. 2,2'-Phthaloyl-,2,2'-isophthaloyl-, and 2,2'-terephthaloylbis[1,1,1-trimethylhydrazinium] dihydroxide, bis(inner salts): synthesis, partition coefficients, toxicity and effect on ganglionic transmission. J Pharm Sci. 1986 Apr; 75(4):407-9. PMID: 2873233.
      Citations:    Fields:    Translation:AnimalsCells
    117. Alkadhi KA. Endplate channel actions of a hemicholinium-3 analog, DMAE. Naunyn Schmiedebergs Arch Pharmacol. 1986 Mar; 332(3):230-5. PMID: 3012371.
      Citations: 1     Fields:    Translation:AnimalsCells
    118. Sabouni MH, Alkadhi KA, Lokhandwala MF. Pharmacological characterization of dopamine receptors in the stellate ganglia with selective DA1 and DA2 receptor agonists and antagonists. J Pharmacol Exp Ther. 1986 Jan; 236(1):65-70. PMID: 2867216.
      Citations:    Fields:    Translation:AnimalsCells
    119. Lokhandwala MF, Watkins HO, Sabouni MH, Alkadhi KA. Pharmacological analysis of the actions of SKF 82526 on cardiovascular dopamine receptors. J Pharmacol Exp Ther. 1985 Aug; 234(2):337-44. PMID: 2862275.
      Citations: 4     Fields:    Translation:AnimalsCells
    120. Cates LA, Li VS, Saddawi BH, Alkadhi KA. Phosphorus-nitrogen compounds. 26. Phosphaminimides. 2. 2,2'-Phosphinylidenebis(1,1,1-trimethylhydrazinium) iodide inner salts as agents affecting ganglionic transmission. J Med Chem. 1985 May; 28(5):595-7. PMID: 2859370.
      Citations:    Fields:    Translation:Animals
    121. Alkadhi KA, Brown TR, Sabouni MH. Inhibitory effect of adenosine on transmission in sympathetic ganglia. Naunyn Schmiedebergs Arch Pharmacol. 1984 Nov; 328(1):16-9. PMID: 6096724.
      Citations:    Fields:    Translation:AnimalsCells
    122. Alkadhi KA, Banks FW. Pre- and postsynaptic actions of valproic acid at the frog neuromuscular junction. Brain Res. 1984 Jul 23; 306(1-2):388-90. PMID: 6087980.
      Citations: 3     Fields:    Translation:AnimalsCells
    123. Taha MN, Alkadhi KA. Effects of Methylmercuric chloride on sympathetic preganglionic nerves. Arch Toxicol. 1982 Jul; 50(2):141-7. PMID: 7125908.
      Citations:    Fields:    Translation:AnimalsCells
    124. Volle RL, Alkadhi KA, Branisteanu DD, Reynolds LS, Epstein PM, Smilowitz H, Lambert JJ, Henderson EG. Ketamine and ditran block end-plate ion conductance and [3H]phencyclidine binding to electric organ membrane. J Pharmacol Exp Ther. 1982 Jun; 221(3):570-6. PMID: 6123584.
      Citations: 5     Fields:    Translation:Animals
    125. Volle RL, Quenzer LF, Patterson BA, Alkadhi KA, Henderson EG. Cyclic guanosine 3':5'-monophosphate accumulation and 45Ca-uptake by rat superior cervical ganglia during preganglionic stimulation. J Pharmacol Exp Ther. 1981 Nov; 219(2):338-43. PMID: 6116799.
      Citations: 1     Fields:    Translation:AnimalsCells
    126. Alkadhi K, Branisteanu DD, Henderson EG, Lambert JJ, Volle RL. Effects of McN-A-343, a cholinomimetic drug, on endplate currents in the frog. Naunyn Schmiedebergs Arch Pharmacol. 1980 Jun; 312(2):117-21. PMID: 6157110.
      Citations:    Fields:    Translation:AnimalsCells
    127. Quenzer L, Yahn D, Alkadhi K, Volle RL. Transmission blockade and stimulation of ganglionic adenylate cyclase by catecholamines. J Pharmacol Exp Ther. 1979 Jan; 208(1):31-6. PMID: 215748.
      Citations: 3     Fields:    Translation:AnimalsCells
    128. Alkadhi KA, McIsaac RJ. Differential blockade of ganglionic transmission by extract from venom gland of black widow spider (Latrodectus mactans). Toxicon. 1974 Dec; 12(6):643-8. PMID: 4156433.
      Citations:    Fields:    Translation:AnimalsCells
    129. Alkadhi KA, McIsaac RJ. Effect of preganglionic nerve stimulation on sensitivity of the superior cervical ganglion to nicotinic blocking agents. Br J Pharmacol. 1974 Aug; 51(4):533-9. PMID: 4155976; PMCID: PMC1778062.
      Citations: 2     Fields:    Translation:Animals
    130. Alkadhi KA, McIsaac RJ. Non-nicotinic transmission during ganglionic block with chlorisondamine and nicotine. Eur J Pharmacol. 1973 Oct; 24(1):78-85. PMID: 4148299.
      Citations: 7     Fields:    Translation:AnimalsCells
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