CAROLYNSMITHCAROLYN SMITH0.000000000000000.000000000000002606SMITH, CAROLYNProfessorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 851812Authorship 898824Authorship 991683Authorship 158917Smith CL, Santen RJ, Komm B and Mirkin S Breast Cancer Research Breast-related effects of selective estrogen receptor modulators and tissue selective estrogen complexes. Breast Cancer Research. 2014; 16:212-226.2014-01-01T00:00:002014Breast-related effects of selective estrogen receptor modulators and tissue selective estrogen complexesAuthorship 350105Authorship 375957Authorship 196055125928299Smith CL, Santen RJ, Komm B, Mirkin SBreast cancer research : BCRBreast-related effects of selective estrogen receptor modulators and tissue-selective estrogen complexes. Breast Cancer Res. 2014 Jun 18; 16(3):212.Breast Cancer Res2014-06-18T00:00:002014Breast-related effects of selective estrogen receptor modulators and tissue-selective estrogen complexes.Bioinformatics & Computational BiologySystems BiologyMD AndersonASHISHKAMATASHISH KAMAT8961KAMAT, ASHISHProfessorBOPENGBO PENG9331PENG, BOAssistant ProfessorBOGDAN ACZERNIAKBOGDAN A CZERNIAK8446CZERNIAK, BOGDAN AProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorBRADLEY MCINTOSHBROOMBRADLEY MCINTOSH BROOM9214BROOM, BRADLEY MCINTOSHProfessorAuthorship 542687Authorship 661662Authorship 8903Authorship 940684Authorship 960283Authorship 962963Authorship 9990733299377Hammond GL, Smith CL, Goping IS, Underhill DA, Harley MJ, Reventos J, Musto NA, Gunsalus GL, Bardin CWProceedings of the National Academy of Sciences of the United States of AmericaPrimary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5153-7.Proc Natl Acad Sci U S A1987-08-01T00:00:001987Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors.3250013Smith CL, Hammond GLSteroidsThe amino acid sequence of rat CBG deduced from a cDNA, and identification of CBG mRNA in the liver under different physiological states. Steroids. 1988 Oct; 52(4):331-2.Steroids1988-10-01T00:00:001988The amino acid sequence of rat CBG deduced from a cDNA, and identification of CBG mRNA in the liver under different physiological states.3569533Hammond GL, Underhill DA, Smith CL, Goping IS, Harley MJ, Musto NA, Cheng CY, Bardin CWFEBS lettersThe cDNA-deduced primary structure of human sex hormone-binding globulin and location of its steroid-binding domain. FEBS Lett. 1987 May 04; 215(1):100-4.FEBS Lett1987-05-04T00:00:001987The cDNA-deduced primary structure of human sex hormone-binding globulin and location of its steroid-binding domain.8756415Apostolakis EM, Garai J, Fox C, Smith CL, Watson SJ, Clark JH, O'Malley BWThe Journal of neuroscience : the official journal of the Society for NeuroscienceDopaminergic regulation of progesterone receptors: brain D5 dopamine receptors mediate induction of lordosis by D1-like agonists in rats. J Neurosci. 1996 Aug 15; 16(16):4823-34.J Neurosci1996-08-15T00:00:001996Dopaminergic regulation of progesterone receptors: brain D5 dopamine receptors mediate induction of lordosis by D1-like agonists in rats.9171229Smith CL, Nawaz Z, O'Malley BWMolecular endocrinology (Baltimore, Md.)Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Mol Endocrinol. 1997 Jun; 11(6):657-66.Mol Endocrinol1997-06-01T00:00:001997Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen.7916682Scrocchi LA, Orava M, Smith CL, Han VK, Hammond GLEndocrinologySpatial and temporal distribution of corticosteroid-binding globulin and its messenger ribonucleic acid in embryonic and fetal mice. Endocrinology. 1993 Feb; 132(2):903-9.Endocrinology1993-02-01T00:00:001993Spatial and temporal distribution of corticosteroid-binding globulin and its messenger ribonucleic acid in embryonic and fetal mice.8299584Hammond GL, Smith CL, L?hteenm?ki P, Grolla A, Warmels-Rodenhiser S, Hodgert H, Murai JT, Siiteri PKEndocrinologySquirrel monkey corticosteroid-binding globulin: primary structure and comparison with the human protein. Endocrinology. 1994 Feb; 134(2):891-8.Endocrinology1994-02-01T00:00:001994Squirrel monkey corticosteroid-binding globulin: primary structure and comparison with the human protein.8327492Smith CL, Conneely OM, O'Malley BWProceedings of the National Academy of Sciences of the United States of AmericaModulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone. Proc Natl Acad Sci U S A. 1993 Jul 01; 90(13):6120-4.Proc Natl Acad Sci U S A1993-07-01T00:00:001993Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone.9510949Smith CLBiology of reproductionCross-talk between peptide growth factor and estrogen receptor signaling pathways. Biol Reprod. 1998 Mar; 58(3):627-32.Biol Reprod1998-03-01T00:00:001998Cross-talk between peptide growth factor and estrogen receptor signaling pathways.9793625Smith CL, Kreutner WArzneimittel-ForschungIn vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids. Arzneimittelforschung. 1998 Sep; 48(9):956-60.Arzneimittelforschung1998-09-01T00:00:001998In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids.9891052Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BWMolecular and cellular biologyThe Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol. 1999 Feb; 19(2):1182-9.Mol Cell Biol1999-02-01T00:00:001999The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily.10051559Nawaz Z, Lonard DM, Dennis AP, Smith CL, O'Malley BWProceedings of the National Academy of Sciences of the United States of AmericaProteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci U S A. 1999 Mar 02; 96(5):1858-62.Proc Natl Acad Sci U S A1999-03-02T00:00:001999Proteasome-dependent degradation of the human estrogen receptor.8799122Smith CL, O?ate SA, Tsai MJ, O'Malley BWProceedings of the National Academy of Sciences of the United States of AmericaCREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc Natl Acad Sci U S A. 1996 Aug 20; 93(17):8884-8.Proc Natl Acad Sci U S A1996-08-20T00:00:001996CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.11578956Coleman KM, Smith CLFrontiers in bioscience : a journal and virtual libraryIntracellular signaling pathways: nongenomic actions of estrogens and ligand-independent activation of estrogen receptors. Front Biosci. 2001 Oct 01; 6:D1379-91.Front Biosci2001-10-01T00:00:002001Intracellular signaling pathways: nongenomic actions of estrogens and ligand-independent activation of estrogen receptors.1425412Yang K, Smith CL, Dales D, Hammond GL, Challis JREndocrinologyCloning of an ovine 11 beta-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid: tissue and temporal distribution of its messenger ribonucleic acid during fetal and neonatal development. Endocrinology. 1992 Nov; 131(5):2120-6.Endocrinology1992-11-01T00:00:001992Cloning of an ovine 11 beta-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid: tissue and temporal distribution of its messenger ribonucleic acid during fetal and neonatal development.One Baylor PlazaHouston, 77030TX12231410Narayanan R, Smith CL, Weigel NLBoneVector-averaged gravity-induced changes in cell signaling and vitamin D receptor activity in MG-63 cells are reversed by a 1,25-(OH)2D3 analog, EB1089. Bone. 2002 Sep; 31(3):381-8.Bone2002-09-01T00:00:002002Vector-averaged gravity-induced changes in cell signaling and vitamin D receptor activity in MG-63 cells are reversed by a 1,25-(OH)2D3 analog, EB1089.10911988Lonard DM, Nawaz Z, Smith CL, O'Malley BWMolecular cellThe 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation. Mol Cell. 2000 Jun; 5(6):939-48.Mol Cell2000-06-01T00:00:002000The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation.11046073Dutertre M, Smith CLThe Journal of pharmacology and experimental therapeuticsMolecular mechanisms of selective estrogen receptor modulator (SERM) action. J Pharmacol Exp Ther. 2000 Nov; 295(2):431-7.J Pharmacol Exp Ther2000-11-01T00:00:002000Molecular mechanisms of selective estrogen receptor modulator (SERM) action.11390668Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MAMolecular and cellular biologyLigand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells. Mol Cell Biol. 2001 Jul; 21(13):4404-12.Mol Cell Biol2001-07-01T00:00:002001Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells.11500235Marino M, Distefano E, Trentalance A, Smith CLMolecular and cellular endocrinologyEstradiol-induced IP(3) mediates the estrogen receptor activity expressed in human cells. Mol Cell Endocrinol. 2001 Aug 20; 182(1):19-26.Mol Cell Endocrinol2001-08-20T00:00:002001Estradiol-induced IP(3) mediates the estrogen receptor activity expressed in human cells.10481159Smith CL, O'Malley BWTrends in endocrinology and metabolism: TEMEvolving concepts of selective estrogen receptor action: from basic science to clinical applications. Trends Endocrinol Metab. 1999 Oct; 10(8):299-300.Trends Endocrinol Metab1999-10-01T00:00:001999Evolving concepts of selective estrogen receptor action: from basic science to clinical applications.10770489Stenoien DL, Mancini MG, Patel K, Allegretto EA, Smith CL, Mancini MAMolecular endocrinology (Baltimore, Md.)Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1. Mol Endocrinol. 2000 Apr; 14(4):518-34.Mol Endocrinol2000-04-01T00:00:002000Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1.74Professor10Assistant Professor54Instructor14Associate Professor16Associate Professor Emeritus78Professor Emeritus6Adjunct Professor47Distinguished Service Professor1504007Smith CL, Power SG, Hammond GLThe Journal of steroid biochemistry and molecular biologyA Leu----His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol. J Steroid Biochem Mol Biol. 1992 Aug; 42(7):671-6.J Steroid Biochem Mol Biol1992-08-01T00:00:001992A Leu----His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol.11146621Stenoien DL, Patel K, Mancini MG, Dutertre M, Smith CL, O'Malley BW, Mancini MANature cell biologyFRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol. 2001 Jan; 3(1):15-23.Nat Cell Biol2001-01-01T00:00:002001FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent.1547738Smith CL, Hammond GLEndocrinologyHormonal regulation of corticosteroid-binding globulin biosynthesis in the male rat. Endocrinology. 1992 Apr; 130(4):2245-51.Endocrinology1992-04-01T00:00:001992Hormonal regulation of corticosteroid-binding globulin biosynthesis in the male rat.16135815Zheng FF, Wu RC, Smith CL, O'Malley BWMolecular and cellular biologyRapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Mol Cell Biol. 2005 Sep; 25(18):8273-84.Mol Cell Biol2005-09-01T00:00:002005Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor.19281373Smith CLJournal of medicinal foodMultiple intracellular signaling pathways cross-talk with the estrogen receptor. J Med Food. 1999; 2(3-4):177.J Med Food1999-01-01T00:00:001999Multiple intracellular signaling pathways cross-talk with the estrogen receptor.2293023Seralini GE, Smith CL, Hammond GLMolecular endocrinology (Baltimore, Md.)Rabbit corticosteroid-binding globulin: primary structure and biosynthesis during pregnancy. Mol Endocrinol. 1990 Aug; 4(8):1166-72.Mol Endocrinol1990-08-01T00:00:001990Rabbit corticosteroid-binding globulin: primary structure and biosynthesis during pregnancy.15456935Cavarretta IT, Martini L, Motta M, Smith CL, Melcangi RCJournal of molecular neuroscience : MNSRC-1 is involved in the control of the gene expression of myelin protein Po. J Mol Neurosci. 2004; 24(2):217-26.J Mol Neurosci2004-01-01T00:00:002004SRC-1 is involved in the control of the gene expression of myelin protein Po.15464364Lee CY, Liu X, Smith CL, Zhang X, Hsu HC, Wang DY, Luo ZPMatrix biology : journal of the International Society for Matrix BiologyThe combined regulation of estrogen and cyclic tension on fibroblast biosynthesis derived from anterior cruciate ligament. Matrix Biol. 2004 Aug; 23(5):323-9.Matrix Biol2004-08-01T00:00:002004The combined regulation of estrogen and cyclic tension on fibroblast biosynthesis derived from anterior cruciate ligament.23015261Smith CL, Migliaccio I, Chaubal V, Wu MF, Pace MC, Hartmaier R, Jiang S, Edwards DP, Guti?rrez MC, Hilsenbeck SG, Oesterreich SBreast cancer research and treatmentElevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence. Breast Cancer Res Treat. 2012 Nov; 136(1):253-65.Breast Cancer Res Treat2012-09-27T00:00:002012Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence.1989877Smith CL, Hammond GLEndocrinologyOntogeny of corticosteroid-binding globulin biosynthesis in the rat. Endocrinology. 1991 Feb; 128(2):983-8.Endocrinology1991-02-01T00:00:001991Ontogeny of corticosteroid-binding globulin biosynthesis in the rat.16840538Jaber BM, Gao T, Huang L, Karmakar S, Smith CLMolecular endocrinology (Baltimore, Md.)The pure estrogen receptor antagonist ICI 182,780 promotes a novel interaction of estrogen receptor-alpha with the 3',5'-cyclic adenosine monophosphate response element-binding protein-binding protein/p300 coactivators. Mol Endocrinol. 2006 Nov; 20(11):2695-710.Mol Endocrinol2006-07-13T00:00:002006The pure estrogen receptor antagonist ICI 182,780 promotes a novel interaction of estrogen receptor-alpha with the 3',5'-cyclic adenosine monophosphate response element-binding protein-binding protein/p300 coactivators.1958574Hammond GL, Smith CL, Underhill DAThe Journal of steroid biochemistry and molecular biologyMolecular studies of corticosteroid binding globulin structure, biosynthesis and function. J Steroid Biochem Mol Biol. 1991; 40(4-6):755-62.J Steroid Biochem Mol Biol1991-01-01T00:00:001991Molecular studies of corticosteroid binding globulin structure, biosynthesis and function.17572228Sonpavde G, Okuno N, Weiss H, Yu J, Shen SS, Younes M, Jian W, Lerner SP, Smith CLUrologyEfficacy of selective estrogen receptor modulators in nude mice bearing human transitional cell carcinoma. Urology. 2007 Jun; 69(6):1221-6.Urology2007-06-01T00:00:002007Efficacy of selective estrogen receptor modulators in nude mice bearing human transitional cell carcinoma.19339517Giamas G, Castellano L, Feng Q, Knippschild U, Jacob J, Thomas RS, Coombes RC, Smith CL, Jiao LR, Stebbing JNucleic acids researchCK1delta modulates the transcriptional activity of ERalpha via AIB1 in an estrogen-dependent manner and regulates ERalpha-AIB1 interactions. Nucleic Acids Res. 2009 May; 37(9):3110-23.Nucleic Acids Res2009-04-01T00:00:002009CK1delta modulates the transcriptional activity of ERalpha via AIB1 in an estrogen-dependent manner and regulates ERalpha-AIB1 interactions.2222468Hammond GL, Smith CL, Underhill CM, Nguyen VTBiochemical and biophysical research communicationsInteraction between corticosteroid binding globulin and activated leukocytes in vitro. Biochem Biophys Res Commun. 1990 Oct 15; 172(1):172-7.Biochem Biophys Res Commun1990-10-15T00:00:001990Interaction between corticosteroid binding globulin and activated leukocytes in vitro.Authorship 100430120043841Williams CC, Basu A, El-Gharbawy A, Carrier LM, Smith CL, Rowan BGBMC biochemistryIdentification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2. BMC Biochem. 2009 Dec 31; 10:36.BMC Biochem2009-12-31T00:00:002009Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.2370299Hammond GL, Smith CL, Paterson NA, Sibbald WJThe Journal of clinical endocrinology and metabolismA role for corticosteroid-binding globulin in delivery of cortisol to activated neutrophils. J Clin Endocrinol Metab. 1990 Jul; 71(1):34-9.J Clin Endocrinol Metab1990-07-01T00:00:001990A role for corticosteroid-binding globulin in delivery of cortisol to activated neutrophils.Authorship 1014243Authorship 101673222965848Hoffman KL, Lerner SP, Smith CLHormones & cancerRaloxifene inhibits growth of RT4 urothelial carcinoma cells via estrogen receptor-dependent induction of apoptosis and inhibition of proliferation. Horm Cancer. 2013 Feb; 4(1):24-35.Horm Cancer2012-09-11T00:00:002012Raloxifene inhibits growth of RT4 urothelial carcinoma cells via estrogen receptor-dependent induction of apoptosis and inhibition of proliferation.2608061Hammond GL, Underhill DA, Rykse HM, Smith CLMolecular endocrinology (Baltimore, Md.)The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs. Mol Endocrinol. 1989 Nov; 3(11):1869-76.Mol Endocrinol1989-11-01T00:00:001989The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs.Authorship 10289087740165O'Malley BW, Schrader WT, Mani S, Smith C, Weigel NL, Conneely OM, Clark JHRecent progress in hormone researchAn alternative ligand-independent pathway for activation of steroid receptors. Recent Prog Horm Res. 1995; 50:333-47.Recent Prog Horm Res1995-01-01T00:00:001995An alternative ligand-independent pathway for activation of steroid receptors.7813219Hammond GL, Bocchinfuso WP, Orava M, Smith CL, van den Ende A, van Enk AContraceptionSerum distribution of two contraceptive progestins: 3-ketodesogestrel and gestodene. Contraception. 1994 Oct; 50(4):301-18.Contraception1994-10-01T00:00:001994Serum distribution of two contraceptive progestins: 3-ketodesogestrel and gestodene.8654870Smith CL, Conneely OM, O'Malley BWBiochemical Society transactionsOestrogen receptor activation in the absence of ligand. Biochem Soc Trans. 1995 Nov; 23(4):935-9.Biochem Soc Trans1995-11-01T00:00:001995Oestrogen receptor activation in the absence of ligand.9671227Stenoien D, Sharp ZD, Smith CL, Mancini MAJournal of cellular biochemistryFunctional subnuclear partitioning of transcription factors. J Cell Biochem. 1998 Aug 01; 70(2):213-21.J Cell Biochem1998-08-01T00:00:001998Functional subnuclear partitioning of transcription factors.11517155Larrea F, Garc?a-Becerra R, Lemus AE, Garc?a GA, P?rez-Palacios G, Jackson KJ, Coleman KM, Dace R, Smith CL, Cooney AJEndocrinologyA-ring reduced metabolites of 19-nor synthetic progestins as subtype selective agonists for ER alpha. Endocrinology. 2001 Sep; 142(9):3791-9.Endocrinology2001-09-01T00:00:002001A-ring reduced metabolites of 19-nor synthetic progestins as subtype selective agonists for ER alpha.11700319Walters MR, Dutertre M, Smith CLThe Journal of biological chemistrySKF-82958 is a subtype-selective estrogen receptor-alpha (ERalpha ) agonist that induces functional interactions between ERalpha and AP-1. J Biol Chem. 2002 Jan 18; 277(3):1669-79.J Biol Chem2001-11-07T00:00:002001SKF-82958 is a subtype-selective estrogen receptor-alpha (ERalpha ) agonist that induces functional interactions between ERalpha and AP-1.14766010Jaber BM, Mukopadhyay R, Smith CLJournal of molecular endocrinologyEstrogen receptor-alpha interaction with the CREB binding protein coactivator is regulated by the cellular environment. J Mol Endocrinol. 2004 Feb; 32(1):307-23.J Mol Endocrinol2004-02-01T00:00:002004Estrogen receptor-alpha interaction with the CREB binding protein coactivator is regulated by the cellular environment.15677324Labhart P, Karmakar S, Salicru EM, Egan BS, Alexiadis V, O'Malley BW, Smith CLProceedings of the National Academy of Sciences of the United States of AmericaIdentification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. Proc Natl Acad Sci U S A. 2005 Feb 01; 102(5):1339-44.Proc Natl Acad Sci U S A2005-01-26T00:00:002005Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator.1917978Smith CL, Hammond GLThe Journal of biological chemistryAn amino acid substitution in biobreeding rat corticosteroid binding globulin results in reduced steroid binding affinity. J Biol Chem. 1991 Oct 05; 266(28):18555-9.J Biol Chem1991-10-05T00:00:001991An amino acid substitution in biobreeding rat corticosteroid binding globulin results in reduced steroid binding affinity.16616843Garc?a-Becerra R, Borja-Cacho E, Cooney AJ, Smith CL, Lemus AE, P?rez-Palacios G, Larrea FThe Journal of steroid biochemistry and molecular biologySynthetic 19-nortestosterone derivatives as estrogen receptor alpha subtype-selective ligands induce similar receptor conformational changes and steroid receptor coactivator recruitment than natural estrogens. J Steroid Biochem Mol Biol. 2006 May; 99(2-3):108-14.J Steroid Biochem Mol Biol2006-04-17T00:00:002006Synthetic 19-nortestosterone derivatives as estrogen receptor alpha subtype-selective ligands induce similar receptor conformational changes and steroid receptor coactivator recruitment than natural estrogens.Authorship 10510320924370Bruning JB, Parent AA, Gil G, Zhao M, Nowak J, Pace MC, Smith CL, Afonine PV, Adams PD, Katzenellenbogen JA, Nettles KWNature chemical biologyCoupling of receptor conformation and ligand orientation determine graded activity. Nat Chem Biol. 2010 Nov; 6(11):837-43.Nat Chem Biol2010-10-10T00:00:002010Coupling of receptor conformation and ligand orientation determine graded activity.2759028Seralini GE, Underhill CM, Smith CL, Nguyen VT, Hammond GLEndocrinologyBiological half-life and transfer of maternal corticosteroid-binding globulin to amniotic fluid in the rabbit. Endocrinology. 1989 Sep; 125(3):1321-5.Endocrinology1989-09-01T00:00:001989Biological half-life and transfer of maternal corticosteroid-binding globulin to amniotic fluid in the rabbit.true1Associate ProfessorAssociate Professortrue1ProfessorProfessorD014156Chemicals & Drugs1160.995888TranscortinD047629Chemicals & Drugs961550.913441Estrogen Receptor betaD011960Chemicals & Drugs44320840.566943Receptors, Estrogen2021-04-30NIHSMITH, CAROLYN LOUISE1997-09-22ESTROGEN RECEPTOR-COREGULATOR FUNCTIONAL INTERACTIONSR01DK0530022009-01-31NIHSMITH, CAROLYN L2004-02-01Negative Regulation of Estrogen ReceptorsR01DK0640382011-05-31NIHSMITH, CAROLYN LOUISE2008-06-01Antiestrogen Regulation of Bladder CancerR03CA1192712018-07-31NIHSMITH, CAROLYN LOUISE2008-08-01Research Education and Career Horizons ProgramK12GM084897Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorD020845Chemicals & Drugs511450.878231Selective Estrogen Receptor ModulatorsD047628Chemicals & Drugs2397010.691901Estrogen Receptor alphaPathologyUrologyDepartment of MedicineGraduate School of Biomedical SciencesDepartment of Molecular & Cellular BiologyDepartment of UrologyUrologyGraduate Sch of Biomedical SciencesMedicine-Hematology & OncologyMolecular & Cellular BiologyBaylor College of MedicineCHADCREIGHTONCHAD CREIGHTON0.000000000000000.000000000000001109CREIGHTON, CHADProfessor1.356330.00146934315research areas0.494480.010932322coauthor of29.60615.0020859similar to1163selected publicationsCASSIUSBORDELON JRCASSIUS BORDELON JR0.000000000000000.000000000000002265BORDELON JR, CASSIUSAssociate Professor EmeritusFRANCESCODEMAYOFRANCESCO DEMAYO0.000000000000000.000000000000003030DEMAYO, FRANCESCOAdjunct ProfessorORLACONNEELYORLA CONNEELY0.000000000000000.000000000000003031CONNEELY, ORLAProfessor EmeritusDONALDMCDONNELLDONALD MCDONNELL0.000000000000000.000000000000003029MCDONNELL, DONALDAdjunct ProfessorRACHELSCHIFFRACHEL SCHIFF29.70508570000000-95.4018087000000098SCHIFF, RACHELProfessorBERTO'MALLEYBERT O'MALLEY0.000000000000000.000000000000002464O'MALLEY, BERTDistinguished Service ProfessorJIANQIANGMAOJIANQIANG MAO0.000000000000000.00000000000000296MAO, JIANQIANGInstructorJOHNLYDONJOHN LYDON0.000000000000000.000000000000003271LYDON, JOHNAssociate ProfessorSUZANNEFUQUASUZANNE FUQUA0.000000000000000.000000000000003633FUQUA, SUZANNEProfessortrue1Distinguished Service ProfessorDistinguished Service Professor2ProfessorProfessor3Senior Associate DeanSenior Associate Deantrue1ProfessorProfessor2025-06-30NIHSMITH, CAROLYN LOUISE;VAN DEN VEYVER, IGNATIA B2020-07-01The Clinical Translational Research Certificate of Added Qualification ProgramT32GM136554true1Adjunct ProfessorAdjunct Professortrue1Adjunct ProfessorAdjunct Professortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 1128522Principal Investigatortrue1Professor EmeritusProfessor EmeritusCo-Principal InvestigatorAuthorship 1165663Authorship 1168294Authorship 1208641true1InstructorInstructorAuthorship 182693true1Associate Professor EmeritusAssociate Professor EmeritusAuthorship 233161Authorship 191481true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant ProfessorAuthorship 200764Authorship 303582Authorship 312017Authorship 256251Authorship 271091Authorship 422411Authorship 310291Authorship 1398402Authorship 1398416Authorship 1398421Authorship 1398434Authorship 1398443Authorship 1398451Authorship 139846Authorship 139847Authorship 1398483934359Younoszai MK, Smith C, Finch MHJournal of pediatric gastroenterology and nutritionComparison of in vitro jejunal uptake of L-valine and L-lysine in the rat during maturation. J Pediatr Gastroenterol Nutr. 1985 Dec; 4(6):992-7.J Pediatr Gastroenterol Nutr1985-12-01T00:00:001985Comparison of in vitro jejunal uptake of L-valine and L-lysine in the rat during maturation.3386241Bardin CW, Gunsalus GL, Musto NA, Cheng CY, Reventos J, Smith C, Underhill DA, Hammond GJournal of steroid biochemistryCorticosteroid binding globulin, testosterone-estradiol binding globulin, and androgen binding protein belong to protein families distinct from steroid receptors. J Steroid Biochem. 1988; 30(1-6):131-9.J Steroid Biochem1988-01-01T00:00:001988Corticosteroid binding globulin, testosterone-estradiol binding globulin, and androgen binding protein belong to protein families distinct from steroid receptors.2710140Smith CL, Hammond GLMolecular endocrinology (Baltimore, Md.)Rat corticosteroid binding globulin: primary structure and messenger ribonucleic acid levels in the liver under different physiological conditions. Mol Endocrinol. 1989 Feb; 3(2):420-6.Mol Endocrinol1989-02-01T00:00:001989Rat corticosteroid binding globulin: primary structure and messenger ribonucleic acid levels in the liver under different physiological conditions.23448346Jiang XR, Wang P, Smith CL, Zhu BTJournal of medicinal chemistrySynthesis of novel estrogen receptor antagonists using metal-catalyzed coupling reactions and characterization of their biological activity. J Med Chem. 2013 Apr 11; 56(7):2779-90.J Med Chem2013-03-26T00:00:002013Synthesis of novel estrogen receptor antagonists using metal-catalyzed coupling reactions and characterization of their biological activity.24476821Cancer Genome Atlas Research NetworkNatureComprehensive molecular characterization of urothelial bladder carcinoma. Nature. 2014 Mar 20; 507(7492):315-22.Nature2014-01-29T00:00:002014Comprehensive molecular characterization of urothelial bladder carcinoma.Kikukawa, S., Smith, C.L. and Tobe, S.S. Physiological Entomology Morphogenetic and gonadotrophic effects of a juvenile hormone analogue ((7s)-hydroprene) in last instar female larvae of Diploptera punctata. Physiological Entomology. 1989; 14:165-172.1989-01-01T00:00:001989Morphogenetic and gonadotrophic effects of a juvenile hormone analogue ((7s)-hydroprene) in last instar female larvae of Diploptera punctataSmith CLMenopause ManagementEstrogen receptor targeted therapies: mechanisms of action and future developments. Menopause Management. 2005; 14(Suppl 1):40-43.2005-01-01T00:00:002005Estrogen receptor targeted therapies: mechanisms of action and future developmentsSmith CL, Brown KA and Simpson ER Translational Endocrinology & Metabolism Regulation of estrogen receptor activity and aromatase expression: roles of selective estrogen receptor modulators and metabolic factors. Translational Endocrinology & Metabolism. 2012; 3:45-73.2012-01-01T00:00:002012Regulation of estrogen receptor activity and aromatase expression: roles of selective estrogen receptor modulators and metabolic factorsAuthorship 501055Authorship 371723Authorship 379771Authorship 422073Authorship 524031Authorship 535892Authorship 531811Authorship 534525Authorship 55793Authorship 818491Authorship 851931Authorship 864672Authorship 865001Authorship 663099Authorship 685865Authorship 692663Authorship 714932Authorship 720754Authorship 753532Authorship 790972Authorship 775125