JENNIFERSPINLERJENNIFER SPINLER29.71073630000000-95.396604500000001036SPINLER, JENNIFERAssistant Professorplugins:FeaturedVideosFeatured Videosprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 800701Authorship 1099443Authorship 507185Authorship 8223236621 FANNINHouston, 77030TX74Professor10Assistant Professor14Associate ProfessorAuthorship 325131127180007Spinler JK, Brown A, Ross CL, Boonma P, Conner ME, Savidge TCAnaerobeAdministration of probiotic kefir to mice with Clostridium difficile infection exacerbates disease. Anaerobe. 2016 Aug; 40:54-7.Anaerobe2016-05-11T00:00:002016Administration of probiotic kefir to mice with Clostridium difficile infection exacerbates disease.15667993Oram DM, Must LM, Spinler JK, Twiddy EM, Holmes RKFEMS microbiology lettersAnalysis of truncated variants of the iron dependent transcriptional regulators from Corynebacterium diphtheriae and Mycobacterium tuberculosis. FEMS Microbiol Lett. 2005 Feb 01; 243(1):1-8.FEMS Microbiol Lett2005-02-01T00:00:002005Analysis of truncated variants of the iron dependent transcriptional regulators from Corynebacterium diphtheriae and Mycobacterium tuberculosis.Authorship 3279941Authorship 3279961Authorship 328285327180006Ross CL, Spinler JK, Savidge TCAnaerobeStructural and functional changes within the gut microbiota and susceptibility to Clostridium difficile infection. Anaerobe. 2016 Oct; 41:37-43.Anaerobe2016-05-12T00:00:002016Structural and functional changes within the gut microbiota and susceptibility to Clostridium difficile infection.27180657Spinler JK, Ross CL, Savidge TCAnaerobeProbiotics as adjunctive therapy for preventing Clostridium difficile infection - What are we waiting for? Anaerobe. 2016 Oct; 41:51-57.Anaerobe2016-05-13T00:00:002016Probiotics as adjunctive therapy for preventing Clostridium difficile infection - What are we waiting for?27353144Thomas CM, Saulnier DM, Spinler JK, Hemarajata P, Gao C, Jones SE, Grimm A, Balderas MA, Burstein MD, Morra C, Roeth D, Kalkum M, Versalovic JMicrobiologyOpenFolC2-mediated folate metabolism contributes to suppression of inflammation by probiotic Lactobacillus reuteri. Microbiologyopen. 2016 Oct; 5(5):802-818.Microbiologyopen2016-06-28T00:00:002016FolC2-mediated folate metabolism contributes to suppression of inflammation by probiotic Lactobacillus reuteri.21559529Saulnier DM, Santos F, Roos S, Mistretta TA, Spinler JK, Molenaar D, Teusink B, Versalovic JPloS oneExploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features. PLoS One. 2011 Apr 29; 6(4):e18783.PLoS One2011-04-29T00:00:002011Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features.21777454Santos F, Spinler JK, Saulnier DM, Molenaar D, Teusink B, de Vos WM, Versalovic J, Hugenholtz JMicrobial cell factoriesFunctional identification in Lactobacillus reuteri of a PocR-like transcription factor regulating glycerol utilization and vitamin B12 synthesis. Microb Cell Fact. 2011 Jul 21; 10:55.Microb Cell Fact2011-07-21T00:00:002011Functional identification in Lactobacillus reuteri of a PocR-like transcription factor regulating glycerol utilization and vitamin B12 synthesis.23600592Olson D, Preidis GA, Milazi R, Spinler JK, Lufesi N, Mwansambo C, Hosseinipour MC, McCollum EDTropical medicine & international health : TM & IHTask shifting an inpatient triage, assessment and treatment programme improves the quality of care for hospitalised Malawian children. Trop Med Int Health. 2013 Jul; 18(7):879-86.Trop Med Int Health2013-04-22T00:00:002013Task shifting an inpatient triage, assessment and treatment programme improves the quality of care for hospitalised Malawian children.18396068Spinler JK, Taweechotipatr M, Rognerud CL, Ou CN, Tumwasorn S, Versalovic JAnaerobeHuman-derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens. Anaerobe. 2008 Jun; 14(3):166-71.Anaerobe2008-02-29T00:00:002008Human-derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens.19222575Taweechotipatr M, Iyer C, Spinler JK, Versalovic J, Tumwasorn SFEMS microbiology lettersLactobacillus saerimneri and Lactobacillus ruminis: novel human-derived probiotic strains with immunomodulatory activities. FEMS Microbiol Lett. 2009 Apr; 293(1):65-72.FEMS Microbiol Lett2009-02-12T00:00:002009Lactobacillus saerimneri and Lactobacillus ruminis: novel human-derived probiotic strains with immunomodulatory activities.19243931Saulnier DM, Spinler JK, Gibson GR, Versalovic JCurrent opinion in biotechnologyMechanisms of probiosis and prebiosis: considerations for enhanced functional foods. Curr Opin Biotechnol. 2009 Apr; 20(2):135-41.Curr Opin Biotechnol2009-02-24T00:00:002009Mechanisms of probiosis and prebiosis: considerations for enhanced functional foods.Authorship 652595227756217Panpetch W, Spinler JK, Versalovic J, Tumwasorn SBMC microbiologyCharacterization of Lactobacillus salivarius strains B37 and B60 capable of inhibiting IL-8 production in Helicobacter pylori-stimulated gastric epithelial cells. BMC Microbiol. 2016 10 18; 16(1):242.BMC Microbiol2016-10-18T00:00:002016Characterization of Lactobacillus salivarius strains B37 and B60 capable of inhibiting IL-8 production in Helicobacter pylori-stimulated gastric epithelial cells.19146571Spinler JK, Zajdowicz SL, Haller JC, Oram DM, Gill RE, Holmes RKFEMS microbiology lettersDevelopment and use of a selectable, broad-host-range reporter transposon for identifying environmentally regulated promoters in bacteria. FEMS Microbiol Lett. 2009 Feb; 291(2):143-50.FEMS Microbiol Lett2009-02-01T00:00:002009Development and use of a selectable, broad-host-range reporter transposon for identifying environmentally regulated promoters in bacteria.Authorship 882734128760934Spinler JK, Auchtung J, Brown A, Boonma P, Oezguen N, Ross CL, Luna RA, Runge J, Versalovic J, Peniche A, Dann SM, Britton RA, Haag A, Savidge TCInfection and immunityNext-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis. Infect Immun. 2017 10; 85(10).Infect Immun2017-09-20T00:00:002017Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis.true1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate ProfessorAuthorship 1075451D004761Disorders501110.905462Enterocolitis, Pseudomembranoustrue1ProfessorProfessorD005985Chemicals & Drugs14320.972061GlyceraldehydeD019936Living Beings882250.785599ProbioticsAuthorship 936223130600139Spinler JK, Karri V, Hirschi KDTrends in microbiologyPlanting the Microbiome. Trends Microbiol. 2019 02; 27(2):90-93.Trends Microbiol2018-12-29T00:00:002018Planting the Microbiome.D011407Chemicals & Drugs15310.972367PropaneDepartment of PediatricsDepartment of Molecular & Human GeneticsDepartment of Molecular Virology & MicrobiologyDepartment of Pathology & ImmunologyImmunologyMolecular & Human GeneticsMolecular Virology & MicrobiologyPathologyPediatrics-GastroenterologyPediatrics-NutritionBaylor College of MedicineUniversity of Houston College of PharmacyCAROLINAGUTIERREZCAROLINA GUTIERREZ29.71073630000000-95.39660450000000100GUTIERREZ, CAROLINAProfessor2.735650.00398394245research areas3.740310.031063731coauthor of130.0335.4244760similar to1146selected publicationsRICHARDKELLERMAYERRICHARD KELLERMAYER29.70508570000000-95.401808700000001082KELLERMAYER, RICHARDProfessorKENDALHIRSCHIKENDAL HIRSCHI0.000000000000000.000000000000003551HIRSCHI, KENDALProfessorWILLIAMDECKERWILLIAM DECKER29.71073630000000-95.3966045000000036DECKER, WILLIAMAssociate ProfessorRUTHLUNARUTH LUNA0.000000000000000.000000000000003631LUNA, RUTHAssociate ProfessorMINCHENMIN CHEN29.71073630000000-95.39660450000000366CHEN, MINAssociate ProfessorROYSILLITOEROY SILLITOE29.71073630000000-95.396604500000004100SILLITOE, ROYProfessorKEVINGAREYKEVIN W. GAREY29.70508570000000-95.401808700000004636GAREY, KEVINProfessor. Chair, Department of Pharmacy Practice and Translational Research.CHRISTOPHEHERMANCHRISTOPHE HERMAN29.71073630000000-95.39660450000000816HERMAN, CHRISTOPHEProfessorJAMESVERSALOVICJAMES VERSALOVIC0.000000000000000.000000000000003197VERSALOVIC, JAMESProfessorTORSAVIDGETOR SAVIDGE0.000000000000000.000000000000004547SAVIDGE, TORProfessorAuthorship 943506230099125Peniche AG, Spinler JK, Boonma P, Savidge TC, Dann SMAnaerobeAging impairs protective host defenses against Clostridioides (Clostridium) difficile infection in mice by suppressing neutrophil and IL-22 mediated immunity. Anaerobe. 2018 Dec; 54:83-91.Anaerobe2018-08-09T00:00:002018Aging impairs protective host defenses against Clostridioides (Clostridium) difficile infection in mice by suppressing neutrophil and IL-22 mediated immunity.D0000691962708980.522246Gastrointestinal Microbiome80Professor. Chair, Department of Pharmacy Practice and Translational Research.true1Professor. Chair, Department of Pharmacy Practice and Translational Research.Professor. Chair, Department of Pharmacy Practice and Translational Research.Pharmacy Practice and Translational ResearchAuthorship 957402131624167Spinler JK, Gonzales-Luna AJ, Raza S, Runge JK, Luna RA, Savidge TC, Garey KWMicrobiology resource announcementsComplete Genome Sequence of Clostridioides difficile Ribotype 255 Strain Mta-79, Assembled Using Oxford Nanopore and Illumina Sequencing. Microbiol Resour Announc. 2019 Oct 17; 8(42).Microbiol Resour Announc2019-10-17T00:00:002019Complete Genome Sequence of Clostridioides difficile Ribotype 255 Strain Mta-79, Assembled Using Oxford Nanopore and Illumina Sequencing.Authorship 9578271Authorship 957829431649076Spinler JK, Raza S, Runge JK, Luna RAMicrobiology resource announcementsComplete Genome Sequence of the Multidrug-Resistant Pseudomonas aeruginosa Endemic Houston-1 Strain, Isolated from a Pediatric Patient with Cystic Fibrosis and Assembled Using Oxford Nanopore and Illumina Sequencing. Microbiol Resour Announc. 2019 Oct 24; 8(43).Microbiol Resour Announc2019-10-24T00:00:002019Complete Genome Sequence of the Multidrug-Resistant Pseudomonas aeruginosa Endemic Houston-1 Strain, Isolated from a Pediatric Patient with Cystic Fibrosis and Assembled Using Oxford Nanopore and Illumina Sequencing.31649646Engevik MA, Morra CN, R?th D, Engevik K, Spinler JK, Devaraj S, Crawford SE, Estes MK, Kalkum M, Versalovic JFrontiers in microbiologyMicrobial Metabolic Capacity for Intestinal Folate Production and Modulation of Host Folate Receptors. Front Microbiol. 2019; 10:2305.Front Microbiol2019-10-09T00:00:002019Microbial Metabolic Capacity for Intestinal Folate Production and Modulation of Host Folate Receptors.true1ProfessorProfessorAuthorship 978302332067143Ruan W, Engevik MA, Spinler JK, Versalovic JDigestive diseases and sciencesHealthy Human Gastrointestinal Microbiome: Composition and Function After a Decade of Exploration. Dig Dis Sci. 2020 03; 65(3):695-705.Dig Dis Sci2020-03-01T00:00:002020Healthy Human Gastrointestinal Microbiome: Composition and Function After a Decade of Exploration.Authorship 986093432223302Engevik MA, Danhof HA, Chang-Graham AL, Spinler JK, Engevik KA, Herrmann B, Endres BT, Garey KW, Hyser JM, Britton RA, Versalovic JAmerican journal of physiology. Gastrointestinal and liver physiologyHuman intestinal enteroids as a model of Clostridioides difficile-induced enteritis. Am J Physiol Gastrointest Liver Physiol. 2020 05 01; 318(5):G870-G888.Am J Physiol Gastrointest Liver Physiol2020-03-30T00:00:002020Human intestinal enteroids as a model of Clostridioides difficile-induced enteritis.24123819Hemarajata P, Gao C, Pflughoeft KJ, Thomas CM, Saulnier DM, Spinler JK, Versalovic JJournal of bacteriologyLactobacillus reuteri-specific immunoregulatory gene rsiR modulates histamine production and immunomodulation by Lactobacillus reuteri. J Bacteriol. 2013 Dec; 195(24):5567-76.J Bacteriol2013-10-11T00:00:002013Lactobacillus reuteri-specific immunoregulatory gene rsiR modulates histamine production and immunomodulation by Lactobacillus reuteri.Authorship 9972811132804011Engevik MA, Danhof HA, Shrestha R, Chang-Graham AL, Hyser JM, Haag AM, Mohammad MA, Britton RA, Versalovic J, Sorg JA, Spinler JKGut microbesReuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generation. Gut Microbes. 2020 11 09; 12(1):1788898.Gut Microbes2020-11-09T00:00:002020Reuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generation.Authorship 1003208933082337Norsigian CJ, Danhof HA, Brand CK, Oezguen N, Midani FS, Palsson BO, Savidge TC, Britton RA, Spinler JK, Monk JMNPJ systems biology and applicationsSystems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence. NPJ Syst Biol Appl. 2020 10 20; 6(1):31.NPJ Syst Biol Appl2020-10-20T00:00:002020Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence.Authorship 1004881933176423Engevik MA, Engevik AC, Engevik KA, Auchtung JM, Chang-Graham AL, Ruan W, Luna RA, Hyser JM, Spinler JK, Versalovic JACS infectious diseasesMucin-Degrading Microbes Release Monosaccharides That Chemoattract Clostridioides difficile and Facilitate Colonization of the Human Intestinal Mucus Layer. ACS Infect Dis. 2021 05 14; 7(5):1126-1142.ACS Infect Dis2020-11-11T00:00:002020Mucin-Degrading Microbes Release Monosaccharides That Chemoattract Clostridioides difficile and Facilitate Colonization of the Human Intestinal Mucus Layer.Authorship 101029617Authorship 1010651133542959Spinler JK, Oezguen N, Runge JK, Luna RA, Karri V, Yang J, Hirschi KDExRNADietary impact of a plant-derived microRNA on the gut microbiome. ExRNA. 2020; 2.ExRNA2020-08-11T00:00:002020Dietary impact of a plant-derived microRNA on the gut microbiome.33516788Ihekweazu FD, Engevik MA, Ruan W, Shi Z, Fultz R, Engevik KA, Chang-Graham AL, Freeborn J, Park ES, Venable S, Horvath TD, Haidacher SJ, Haag AM, Goodwin A, Schady DA, Hyser JM, Spinler JK, Liu Y, Versalovic JThe American journal of pathologyBacteroides ovatus Promotes IL-22 Production and Reduces Trinitrobenzene Sulfonic Acid-Driven Colonic Inflammation. Am J Pathol. 2021 04; 191(4):704-719.Am J Pathol2021-01-28T00:00:002021Bacteroides ovatus Promotes IL-22 Production and Reduces Trinitrobenzene Sulfonic Acid-Driven Colonic Inflammation.Authorship 10126311533653893Engevik MA, Danhof HA, Ruan W, Engevik AC, Chang-Graham AL, Engevik KA, Shi Z, Zhao Y, Brand CK, Krystofiak ES, Venable S, Liu X, Hirschi KD, Hyser JM, Spinler JK, Britton RA, Versalovic JmBioFusobacterium nucleatum Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation. mBio. 2021 03 02; 12(2).mBio2021-03-02T00:00:002021Fusobacterium nucleatum Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation.Authorship 1017510333934744Marquez L, Koy T, Spinler JK, Luna RA, Tocco L, Fasciano L, Dunn J, Campbell JRInfection control and hospital epidemiologyReinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.7 variant in an immunocompromised adolescent. Infect Control Hosp Epidemiol. 2022 08; 43(8):1088-1090.Infect Control Hosp Epidemiol2021-05-03T00:00:002021Reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.7 variant in an immunocompromised adolescent.Authorship 10183751833985416Engevik MA, Herrmann B, Ruan W, Engevik AC, Engevik KA, Ihekweazu F, Shi Z, Luck B, Chang-Graham AL, Esparza M, Venable S, Horvath TD, Haidacher SJ, Hoch KM, Haag AM, Schady DA, Hyser JM, Spinler JK, Versalovic JGut microbesBifidobacterium dentium-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation. Gut Microbes. 2021 Jan-Dec; 13(1):1-21.Gut Microbes2021-01-01T00:00:002021Bifidobacterium dentium-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation.Authorship 101930312Authorship 1019484234044101Gonzales-Luna AJ, Spinler JK, Oezguen N, Khan MAW, Danhof HA, Endres BT, Alam MJ, Begum K, Lancaster C, Costa GP, Savidge TC, Hurdle JG, Britton R, Garey KWAnaerobeSystems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation. Anaerobe. 2021 Aug; 70:102387.Anaerobe2021-05-24T00:00:002021Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation.34030655Engevik MA, Danhof HA, Hall A, Engevik KA, Horvath TD, Haidacher SJ, Hoch KM, Endres BT, Bajaj M, Garey KW, Britton RA, Spinler JK, Haag AM, Versalovic JBMC microbiologyThe metabolic profile of Bifidobacterium dentium reflects its status as a human gut commensal. BMC Microbiol. 2021 05 24; 21(1):154.BMC Microbiol2021-05-24T00:00:002021The metabolic profile of Bifidobacterium dentium reflects its status as a human gut commensal.Authorship 1028451834439760Luck B, Horvath TD, Engevik KA, Ruan W, Haidacher SJ, Hoch KM, Oezguen N, Spinler JK, Haag AM, Versalovic J, Engevik MABiomoleculesNeurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with Bifidobacterium dentium. Biomolecules. 2021 07 23; 11(8).Biomolecules2021-07-23T00:00:002021Neurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with Bifidobacterium dentium.Authorship 1030165934550056Engevik M, Ruan W, Visuthranukul C, Shi Z, Engevik KA, Engevik AC, Fultz R, Schady DA, Spinler JK, Versalovic JBeneficial microbesLimosilactobacillus reuteri ATCC 6475 metabolites upregulate the serotonin transporter in the intestinal epithelium. Benef Microbes. 2021 Nov 16; 12(6):583-599.Benef Microbes2021-09-22T00:00:002021Limosilactobacillus reuteri ATCC 6475 metabolites upregulate the serotonin transporter in the intestinal epithelium.Authorship 10335249Authorship 1034089134775029Spinler JK, Raza S, Thapa S, Venkatachalam A, Scott T, Runge JK, Dunn J, Versalovic J, Luna RAThe Journal of molecular diagnostics : JMDComparison of Whole Genome Sequencing and Repetitive Element PCR for Multidrug-Resistant Pseudomonas aeruginosa Strain Typing. J Mol Diagn. 2022 02; 24(2):158-166.J Mol Diagn2021-11-12T00:00:002021Comparison of Whole Genome Sequencing and Repetitive Element PCR for Multidrug-Resistant Pseudomonas aeruginosa Strain Typing.34724447Kellermayer R, Wu Q, Nagy-Szakal D, Queliza K, Ihekweazu FD, Bocchini CE, Magee AR, Oezguen N, Spinler JK, Hollister EB, Shulman RJ, Versalovic J, Luna RA, Savidge TCJournal of pediatric gastroenterology and nutritionFecal Microbiota Transplantation Commonly Failed in Children With Co-Morbidities. J Pediatr Gastroenterol Nutr. 2022 02 01; 74(2):227-235.J Pediatr Gastroenterol Nutr2022-02-01T00:00:002022Fecal Microbiota Transplantation Commonly Failed in Children With Co-Morbidities.true1ProfessorProfessorAuthorship 1035437834899632Fultz R, Ticer T, Ihekweazu FD, Horvath TD, Haidacher SJ, Hoch KM, Bajaj M, Spinler JK, Haag AM, Buffington SA, Engevik MAFrontiers in microbiologyUnraveling the Metabolic Requirements of the Gut Commensal Bacteroides ovatus. Front Microbiol. 2021; 12:745469.Front Microbiol2021-11-25T00:00:002021Unraveling the Metabolic Requirements of the Gut Commensal Bacteroides ovatus.true1Associate ProfessorAssociate ProfessorAuthorship 1044595935476524Norsigian CJ, Danhof HA, Brand CK, Midani FS, Broddrick JT, Savidge TC, Britton RA, Palsson BO, Spinler JK, Monk JMProceedings of the National Academy of Sciences of the United States of AmericaSystems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power. Proc Natl Acad Sci U S A. 2022 05 03; 119(18):e2119396119.Proc Natl Acad Sci U S A2022-04-27T00:00:002022Systems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power.Authorship 1373126Authorship 10448951035494230Horvath TD, Ihekweazu FD, Haidacher SJ, Ruan W, Engevik KA, Fultz R, Hoch KM, Luna RA, Oezguen N, Spinler JK, Haag AM, Versalovic J, Engevik MAiScienceBacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters. iScience. 2022 May 20; 25(5):104158.iScience2022-03-25T00:00:002022Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters.true1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant ProfessorAuthorship 10601491036352124Horvath TD, Haidacher SJ, Engevik MA, Luck B, Ruan W, Ihekweazu F, Bajaj M, Hoch KM, Oezguen N, Spinler JK, Versalovic J, Haag AMNature protocolsInterrogation of the mammalian gut-brain axis using LC-MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models. Nat Protoc. 2023 02; 18(2):490-529.Nat Protoc2022-11-09T00:00:002022Interrogation of the mammalian gut-brain axis using LC-MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models.true1ProfessorProfessor The microbiome and fecal microbiota transplantationAuthorship 179102Authorship 1413132Authorship 142797224387083Thiraworawong T, Spinler JK, Werawatganon D, Klaikeaw N, Venable SF, Versalovic J, Tumwasorn SHelicobacterAnti-inflammatory properties of gastric-derived Lactobacillus plantarum XB7 in the context of Helicobacter pylori infection. Helicobacter. 2014 Apr; 19(2):144-55.Helicobacter2014-01-05T00:00:002014Anti-inflammatory properties of gastric-derived Lactobacillus plantarum XB7 in the context of Helicobacter pylori infection.24488273Hemarajata P, Spinler JK, Balderas MA, Versalovic JAntonie van LeeuwenhoekIdentification of a proton-chloride antiporter (EriC) by Himar1 transposon mutagenesis in Lactobacillus reuteri and its role in histamine production. Antonie Van Leeuwenhoek. 2014 Mar; 105(3):579-92.Antonie Van Leeuwenhoek2014-02-01T00:00:002014Identification of a proton-chloride antiporter (EriC) by Himar1 transposon mutagenesis in Lactobacillus reuteri and its role in histamine production.Authorship 1484512Authorship 1489451Authorship 148961624951561Spinler JK, Sontakke A, Hollister EB, Venable SF, Oh PL, Balderas MA, Saulnier DM, Mistretta TA, Devaraj S, Walter J, Versalovic J, Highlander SKGenome biology and evolutionFrom prediction to function using evolutionary genomics: human-specific ecotypes of Lactobacillus reuteri have diverse probiotic functions. Genome Biol Evol. 2014 Jun 19; 6(7):1772-89.Genome Biol Evol2014-06-19T00:00:002014From prediction to function using evolutionary genomics: human-specific ecotypes of Lactobacillus reuteri have diverse probiotic functions.24989059Boonma P, Spinler JK, Venable SF, Versalovic J, Tumwasorn SBMC microbiologyLactobacillus rhamnosus L34 and Lactobacillus casei L39 suppress Clostridium difficile-induced IL-8 production by colonic epithelial cells. BMC Microbiol. 2014 Jul 02; 14:177.BMC Microbiol2014-07-02T00:00:002014Lactobacillus rhamnosus L34 and Lactobacillus casei L39 suppress Clostridium difficile-induced IL-8 production by colonic epithelial cells.24991904Finocchario-Kessler S, Gautney BJ, Khamadi S, Okoth V, Goggin K, Spinler JK, Mwangi A, Kimanga D, Clark KF, Olungae HD, Preidis GA, HITSystem TeamAIDS (London, England)If you text them, they will come: using the HIV infant tracking system to improve early infant diagnosis quality and retention in Kenya. AIDS. 2014 Jul; 28 Suppl 3:S313-21.AIDS2014-07-01T00:00:002014If you text them, they will come: using the HIV infant tracking system to improve early infant diagnosis quality and retention in Kenya.Authorship 530712Authorship 151730225197459Boonma P, Spinler JK, Qin X, Jittaprasatsin C, Muzny DM, Doddapaneni H, Gibbs R, Petrosino J, Tumwasorn S, Versalovic JStandards in genomic sciencesDraft genome sequences and description of Lactobacillus rhamnosus strains L31, L34, and L35. Stand Genomic Sci. 2014 Jun 15; 9(3):744-54.Stand Genomic Sci2014-02-15T00:00:002014Draft genome sequences and description of Lactobacillus rhamnosus strains L31, L34, and L35.ROBERTBRITTONROBERT BRITTON8068BRITTON, ROBERTProfessorAuthorship 748704