"Rotenone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A botanical insecticide that is an inhibitor of mitochondrial electron transport.
| Descriptor ID |
D012402
|
| MeSH Number(s) |
D03.383.663.283.266.450.400.843 D03.633.100.150.266.450.400.843 D03.633.400.825
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rotenone".
Below are MeSH descriptors whose meaning is more specific than "Rotenone".
This graph shows the total number of publications written about "Rotenone" by people in this website by year, and whether "Rotenone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 3 | 1 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Rotenone" by people in Profiles.
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Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport. Oncotarget. 2016 Aug 09; 7(32):51435-51449.
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NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's disease. Sci Rep. 2016 Mar 10; 6:22866.
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Rotenone affects p53 transcriptional activity and apoptosis via targeting SIRT1 and H3K9 acetylation in SH-SY5Y cells. J Neurochem. 2015 Aug; 134(4):668-76.
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Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells. FEBS Lett. 2014 Jan 31; 588(3):472-81.
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Expression of human E46K-mutated a-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment. Exp Neurol. 2013 Feb; 240:44-56.
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Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-?-hydroxybutyrate intervention. Biochem Biophys Res Commun. 2012 Sep 28; 426(3):438-44.
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Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease. Neurosignals. 2011; 19(3):163-74.
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Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. J Biol Chem. 2011 May 06; 286(18):16504-15.
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Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells. Neurochem Int. 2010 Oct; 57(3):198-205.
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A novel look into estrogen receptor-negative breast cancer prevention with the natural, multifunctional signal transduction inhibitor deguelin. Cancer Prev Res (Phila). 2009 Nov; 2(11):915-8.