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GEORGE JACKSON

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neurology
Address2002 HOLCOMBE
Houston, TX 77030
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    Collapse Research 
    Collapse research activities and funding
    R01NS046489     (JACKSON, GEORGE R)Jul 15, 2004 - Jun 30, 2009
    NIH/NINDS
    Molecular Genetics of Tau-Associated Neurodegeneration
    Role: Principal Investigator
    K08NS002116     (JACKSON, GEORGE R)Jul 5, 1999 - Aug 31, 2004
    NIH/NINDS
    Molecular Genetics of Polyglutamine-Induced Degeneration
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yusuff T, Chang YC, Sang TK, Jackson GR, Chatterjee S. Codon-optimized TDP-43 mediates neurodegeneration in a Drosophila model of ALS/FTLD. Front Genet. 2023; 14:881638. PMID: 36968586; PMCID: PMC10034021.
      Citations:    
    2. Vaughan CP, Burningham Z, Kelleher JL, McGwin G, Jasien CL, Hastings SN, Stevens MB, Morris I, Jackson GL, The?EQUIPPED VA Implementation QI Group. A cluster-randomized trial of two implementation strategies to deliver audit and feedback in the EQUIPPED medication safety program. Acad Emerg Med. 2023 04; 30(4):340-348. PMID: 36790188.
      Citations:    Fields:    Translation:HumansPHPublic Health
    3. Everett CM, Christy J, Morgan PA, Docherty SL, Smith VA, Anderson JB, Viera A, Jackson GL. When is caring sharing? Primary care provider interdependence and continuity of care. JAAPA. 2023 Jan 01; 36(1):32-40. PMID: 36484712.
      Citations: 1     Fields:    Translation:Humans
    4. Shah C, Jackson GR, Sarwar AI, Mandava P, Jamal F. Treatment Patterns in Essential Tremor: A Retrospective Analysis. Tremor Other Hyperkinet Mov (N Y). 2022; 12:10. PMID: 35415009; PMCID: PMC8954883.
      Citations:    Fields:    Translation:Humans
    5. Everett CM, Docherty SL, Matheson E, Morgan PA, Price A, Christy J, Michener L, Smith VA, Anderson JB, Viera A, Jackson GL. Teaming up in primary care: Membership boundaries, interdependence, and coordination. JAAPA. 2022 Feb 01; 35(2):1-10. PMID: 34985006; PMCID: PMC9869344.
      Citations:    Fields:    Translation:Humans
    6. Everett CM, Jackson GL, Morgan P. Why the science of healthcare delivery matters to practicing PAs. JAAPA. 2020 Mar; 33(3):51-53. PMID: 32097217.
      Citations: 2     Fields:    Translation:Humans
    7. Jackson GL, Cutrona SL, Kilbourne A, White BS, Everett C, Damschroder LJ. Implementation science: Helping healthcare systems improve. JAAPA. 2020 01; 33(1):51-53. PMID: 31880652.
      Citations: 3     Fields:    Translation:Humans
    8. Derry PJ, Hegde ML, Jackson GR, Kayed R, Tour JM, Tsai AL, Kent TA. Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective. Prog Neurobiol. 2020 01; 184:101716. PMID: 31604111; PMCID: PMC7850812.
      Citations: 37     Fields:    Translation:HumansAnimals
    9. Chatterjee S, Ambegaokar SS, Jackson GR, Mudher A. Insulin-Mediated Changes in Tau Hyperphosphorylation and Autophagy in a Drosophila Model of Tauopathy and Neuroblastoma Cells. Front Neurosci. 2019; 13:801. PMID: 31427921; PMCID: PMC6688711.
      Citations: 5     
    10. Everett CM, Morgan P, Smith VA, Woolson S, Edelman D, Hendrix CC, Berkowitz T, White B, Jackson GL. Primary care provider type: Are there differences in patients' intermediate diabetes outcomes? JAAPA. 2019 Jun; 32(6):36-42. PMID: 31136399.
      Citations: 4     Fields:    Translation:Humans
    11. Jackson GR. Lifestyles of a Toxic Twosome: A Novel Tau Strain Induced by a-Synuclein Oligomers. Biol Psychiatry. 2018 10 01; 84(7):472-473. PMID: 30176989.
      Citations: 1     Fields:    
    12. Jackson GR. SCA31 Flies Perform in a Balancing Act between RAN Translation and RNA-Binding Proteins. Neuron. 2017 04 05; 94(1):4-5. PMID: 28384473.
      Citations:    Fields:    Translation:Animals
    13. Bryant MS, Workman CD, Jamal F, Meng H, Jackson GR. Feasibility study: Effect of hand resistance exercise on handwriting in Parkinson's disease and essential tremor. J Hand Ther. 2018 Jan - Mar; 31(1):29-34. PMID: 28389133.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    14. Kinsinger LS, Anderson C, Kim J, Larson M, Chan SH, King HA, Rice KL, Slatore CG, Tanner NT, Pittman K, Monte RJ, McNeil RB, Grubber JM, Kelley MJ, Provenzale D, Datta SK, Sperber NS, Barnes LK, Abbott DH, Sims KJ, Whitley RL, Wu RR, Jackson GL. Implementation of Lung Cancer Screening in the Veterans Health Administration. JAMA Intern Med. 2017 03 01; 177(3):399-406. PMID: 28135352.
      Citations: 112     Fields:    Translation:Humans
    15. Everett CM, Morgan P, Jackson GL. Patient characteristics associated with primary care PA and APRN roles. JAAPA. 2016 Dec; 29(12):1-6. PMID: 27898563.
      Citations: 3     Fields:    Translation:Humans
    16. Jackson GL, Weinberger M, Kirshner MA, Stechuchak KM, Melnyk SD, Bosworth HB, Coffman CJ, Neelon B, Van Houtven C, Gentry PW, Morris IJ, Rose CM, Taylor JP, May CL, Han B, Wainwright C, Alkon A, Powell L, Edelman D. Open-label randomized trial of titrated disease management for patients with hypertension: Study design and baseline sample characteristics. Contemp Clin Trials. 2016 09; 50:5-15. PMID: 27417982; PMCID: PMC5035600.
      Citations: 1     Fields:    Translation:Humans
    17. Chouhan AK, Guo C, Hsieh YC, Ye H, Senturk M, Zuo Z, Li Y, Chatterjee S, Botas J, Jackson GR, Bellen HJ, Shulman JM. Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62. PMID: 27338814; PMCID: PMC4918017.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    18. Zullig LL, Smith VA, Jackson GL, Danus S, Schnell M, Lindquist J, Provenzale D, Weinberger M, Kelley MJ, Bosworth HB. Colorectal Cancer Statistics From the Veterans Affairs Central Cancer Registry. Clin Colorectal Cancer. 2016 12; 15(4):e199-e204. PMID: 27301717; PMCID: PMC5099105.
      Citations: 15     Fields:    Translation:Humans
    19. Iyer J, Wang Q, Le T, Pizzo L, Ambegaokar SS, Imai Y, Srivastava A, Mardon G, Artero R, Jackson GR, Isaacs AM, Partridge L, Lu B, Kumar JP, Girirajan S, Gr?nke S, Trois? BL. Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster. G3 (Bethesda). 2016 05 03; 6(5):1427-37. PMID: 26994292; PMCID: PMC4856093.
      Citations: 19     Fields:    Translation:Animals
    20. Moss JM, Bryan WE, Wilkerson LM, Jackson GL, Owenby RK, Van Houtven C, Stevens MB, Powers JS, Vaughan CP, Hung WW, Hwang U, Markland AD, McGwin G, Hastings SN. Impact of Clinical Pharmacy Specialists on the Design and Implementation of a Quality Improvement Initiative to Decrease Inappropriate Medications in a Veterans Affairs Emergency Department. J Manag Care Spec Pharm. 2016 Jan; 22(1):74-80. PMID: 27015054; PMCID: PMC10397930.
      Citations: 10     Fields:    Translation:Humans
    21. Bryant MS, Jackson GR, Hou JG, Protas EJ. Treadmill exercise tests in persons with Parkinson's disease: responses and disease severity. Aging Clin Exp Res. 2016 Oct; 28(5):1009-14. PMID: 26590841.
      Citations: 4     Fields:    Translation:Humans
    22. Bryant MS, Workman CD, Jackson GR. Multidirectional walk test in individuals with Parkinson's disease: a validity study. Int J Rehabil Res. 2015 Mar; 38(1):88-91. PMID: 25371075.
      Citations: 4     Fields:    Translation:Humans
    23. Sengupta U, Castillo-Carranza DL, Lasagna-Reeves CA, Gerson JE, Paulucci-Holthauzen AA, Krishnamurthy S, Farhed M, Jackson GR, Kayed R, Guerrero-Mu?oz MJ. Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies. Biol Psychiatry. 2015 Nov 15; 78(10):672-83. PMID: 25676491.
      Citations: 72     Fields:    Translation:HumansCells
    24. Nieuwsma JA, Jackson GL, DeKraai MB, Bulling DJ, Cantrell WC, Rhodes JE, Bates MJ, Ethridge K, Lane ME, Tenhula WN, Batten SV, Meador KG. Collaborating across the Departments of Veterans Affairs and Defense to integrate mental health and chaplaincy services. J Gen Intern Med. 2014 Dec; 29 Suppl 4:885-94. PMID: 25355089; PMCID: PMC4239284.
      Citations: 6     Fields:    Translation:Humans
    25. Jackson GR. Learn to forget: regulation of age-related memory impairment by neuronal-glial crosstalk. Neuron. 2014 Nov 19; 84(4):658-9. PMID: 25459404.
      Citations:    Fields:    Translation:AnimalsCells
    26. Castillo-Carranza DL, Krishnamurthy S, Paulucci-Holthauzen AA, Sengupta U, Lasagna-Reeves CA, Ahmad Y, Jackson GR, Kayed R, Guerrero-Mu?oz MJ. Amyloid-? oligomers as a template for secondary amyloidosis in Alzheimer's disease. Neurobiol Dis. 2014 Nov; 71:14-23. PMID: 25134727.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    27. Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathol Commun. 2014 May 29; 2:56. PMID: 24887264; PMCID: PMC4231072.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    28. Yassin AM, Shroff S, Patel SD, Paker AM, Berman MA, Jackson GR. Hemichorea in a patient with diabetic ketoacidosis. J Neurol Sci. 2014 Jul 15; 342(1-2):189-91. PMID: 24857350.
      Citations: 4     Fields:    Translation:Humans
    29. Castillo-Carranza DL, Sengupta U, Lasagna-Reeves CA, Gerson JE, Singh G, Estes DM, Barrett AD, Dineley KT, Jackson GR, Kayed R, Guerrero-Mu?oz MJ. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. J Neurosci. 2014 Mar 19; 34(12):4260-72. PMID: 24647946; PMCID: PMC6608097.
      Citations: 125     Fields:    Translation:AnimalsCells
    30. Bakhoum MF, Bakhoum CY, Ding Z, Carlton SM, Campbell GA, Jackson GR. Evidence for autophagic gridlock in aging and neurodegeneration. Transl Res. 2014 Jul; 164(1):1-12. PMID: 24561013.
      Citations: 4     Fields:    Translation:HumansAnimals
    31. van Ryn M, Phelan SM, Arora NK, Haggstrom DA, Jackson GL, Zafar SY, Griffin JM, Zullig LL, Provenzale D, Yeazel MW, Jindal RM, Clauser SB. Patient-reported quality of supportive care among patients with colorectal cancer in the Veterans Affairs Health Care System. J Clin Oncol. 2014 Mar 10; 32(8):809-15. PMID: 24493712; PMCID: PMC3940539.
      Citations: 14     Fields:    Translation:Humans
    32. Roy B, Jackson GR. Interactions between Tau and a-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease. Hum Mol Genet. 2014 Jun 01; 23(11):3008-23. PMID: 24430504; PMCID: PMC4014195.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    33. Choksi DK, Roy B, Chatterjee S, Yusuff T, Bakhoum MF, Sengupta U, Ambegaokar S, Kayed R, Jackson GR. TDP-43 Phosphorylation by casein kinase Ie promotes oligomerization and enhances toxicity in vivo. Hum Mol Genet. 2014 Feb 15; 23(4):1025-35. PMID: 24105464.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    34. Wightman PJ, Jackson GR, Dipple KM. Disruption of glycerol metabolism by RNAi targeting of genes encoding glycerol kinase results in a range of phenotype severity in Drosophila. PLoS One. 2013; 8(9):e71664. PMID: 24039719; PMCID: PMC3765373.
      Citations: 1     Fields:    Translation:HumansAnimals
    35. Zullig LL, Jackson GL, Weinberger M, Provenzale D, Reeve BB, Carpenter WR. An examination of racial differences in process and outcome of colorectal cancer care quality among users of the veterans affairs health care system. Clin Colorectal Cancer. 2013 Dec; 12(4):255-60. PMID: 23988481; PMCID: PMC3838793.
      Citations: 8     Fields:    Translation:Humans
    36. Hawkins BE, Krishnamurthy S, Castillo-Carranza DL, Sengupta U, Prough DS, Jackson GR, DeWitt DS, Kayed R. Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies. J Biol Chem. 2013 Jun 07; 288(23):17042-17050. PMID: 23632019; PMCID: PMC3675635.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    37. Nieuwsma JA, Rhodes JE, Jackson GL, Cantrell WC, Lane ME, Bates MJ, Dekraai MB, Bulling DJ, Ethridge K, Drescher KD, Fitchett G, Tenhula WN, Milstein G, Bray RM, Meador KG. Chaplaincy and mental health in the department of Veterans affairs and department of defense. J Health Care Chaplain. 2013; 19(1):3-21. PMID: 23551047.
      Citations: 18     Fields:    Translation:Humans
    38. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Sci Rep. 2012; 2:700. PMID: 23050084; PMCID: PMC3463004.
      Citations: 206     Fields:    Translation:HumansAnimalsCells
    39. Ambegaokar SS, Jackson GR. The downward spiral of tau and autolysosomes: a new hypothesis in neurodegeneration. Autophagy. 2012 Jul 01; 8(7):1144-5. PMID: 22635052; PMCID: PMC3429552.
      Citations: 10     Fields:    Translation:HumansAnimals
    40. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bourquin JP, Boya P, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490; PMCID: PMC3404883.
      Citations: 1751     Fields:    Translation:HumansAnimals
    41. Wightman PJ, Jackson GR, Dipple KM. Glycerol hypersensitivity in a Drosophila model for glycerol kinase deficiency is affected by mutations in eye pigmentation genes. PLoS One. 2012; 7(3):e31779. PMID: 22427807; PMCID: PMC3302884.
      Citations: 3     Fields:    Translation:Animals
    42. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Sarmiento J, Troncoso J, Jackson GR, Kayed R. Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. FASEB J. 2012 May; 26(5):1946-59. PMID: 22253473; PMCID: PMC4046102.
      Citations: 204     Fields:    Translation:HumansCells
    43. Jackson GR, Scott IU, Quillen DA, Walter LE, Gardner TW. Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy. Br J Ophthalmol. 2012 May; 96(5):699-703. PMID: 22174096.
      Citations: 56     Fields:    Translation:HumansCells
    44. Clos AL, Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Jackson GR, Kelly B, Beachkofsky TM, Kayed R. Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis. Br J Dermatol. 2011 Dec; 165(6):1349-54. PMID: 21729025.
      Citations: 4     Fields:    Translation:HumansCells
    45. Ambegaokar SS, Jackson GR. Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. Hum Mol Genet. 2011 Dec 15; 20(24):4947-77. PMID: 21949350; PMCID: PMC3221533.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    46. Lasagna-Reeves CA, Castillo-Carranza DL, Jackson GR, Kayed R. Tau oligomers as potential targets for immunotherapy for Alzheimer's disease and tauopathies. Curr Alzheimer Res. 2011 Sep; 8(6):659-65. PMID: 21605039.
      Citations: 33     Fields:    Translation:Humans
    47. Clos AL, Lasagna-Reeves CA, Kelly B, Wagner R, Wilkerson M, Jackson GR, Kayed R. Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis. J Am Acad Dermatol. 2011 Nov; 65(5):1023-31. PMID: 21669474.
      Citations: 3     Fields:    Translation:HumansCells
    48. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R. Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Mol Neurodegener. 2011 Jun 06; 6:39. PMID: 21645391; PMCID: PMC3224595.
      Citations: 219     Fields:    
    49. Kayed R, Jackson GR, Estes DM, Barrett AD. Alzheimers disease: review of emerging treatment role for intravenous immunoglobulins. J Cent Nerv Syst Dis. 2011; 3:67-73. PMID: 23861639; PMCID: PMC3663607.
      Citations: 3     
    50. Bosworth HB, Dubard CA, Ruppenkamp J, Trygstad T, Hewson DL, Jackson GL. Evaluation of a self-management implementation intervention to improve hypertension control among patients in Medicaid. Transl Behav Med. 2011 Mar; 1(1):191-9. PMID: 24073040; PMCID: PMC3717688.
      Citations: 12     Fields:    
    51. Chang YC, Hung WT, Chang YC, Chang HC, Wu CL, Chiang AS, Jackson GR, Sang TK. Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model. PLoS Genet. 2011 Feb 03; 7(2):e1001288. PMID: 21304887; PMCID: PMC3033380.
      Citations: 27     Fields:    Translation:HumansAnimals
    52. Bakhoum MF, Jackson GR. Demise of the flies: why Drosophila models still matter. Prog Mol Biol Transl Sci. 2011; 100:483-98. PMID: 21377634.
      Citations: 2     Fields:    Translation:HumansAnimals
    53. Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R. Preparation and characterization of neurotoxic tau oligomers. Biochemistry. 2010 Nov 30; 49(47):10039-41. PMID: 21047142.
      Citations: 159     Fields:    Translation:HumansCells
    54. Clos AL, Lasagna-Reeves CA, Wagner R, Kelly B, Jackson GR, Kayed R. Therapeutic removal of amyloid deposits in cutaneous amyloidosis by localised intra-lesional injections of anti-amyloid antibodies. Exp Dermatol. 2010 Oct; 19(10):904-11. PMID: 20626464.
      Citations: 3     Fields:    Translation:HumansAnimals
    55. Lasagna-Reeves CA, Clos AL, Midoro-Hiriuti T, Goldblum RM, Jackson GR, Kayed R. Inhaled insulin forms toxic pulmonary amyloid aggregates. Endocrinology. 2010 Oct; 151(10):4717-24. PMID: 20685871.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    56. Ambegaokar SS, Jackson GR. Interaction between eye pigment genes and tau-induced neurodegeneration in Drosophila melanogaster. Genetics. 2010 Sep; 186(1):435-42. PMID: 20592261; PMCID: PMC2940309.
      Citations: 10     Fields:    Translation:AnimalsCells
    57. Ambegaokar SS, Roy B, Jackson GR. Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosis. Neurobiol Dis. 2010 Oct; 40(1):29-39. PMID: 20561920; PMCID: PMC2926295.
      Citations: 26     Fields:    Translation:HumansAnimals
    58. Barrett AD, Kayed R, Jackson GR, Cunningham KA. New vaccine development for chronic brain disease. Neuropsychopharmacology. 2010 Jan; 35(1):354. PMID: 20010720; PMCID: PMC3055416.
      Citations: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    59. Kuo SH, Jackson GR. Emerging subspecialties in neurology: translational research in movement disorders. Neurology. 2009 Aug 25; 73(8):e40-1. PMID: 19704074; PMCID: PMC2731622.
      Citations: 2     Fields:    Translation:HumansAnimals
    60. Kayed R, Jackson GR. Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders. Curr Opin Immunol. 2009 Jun; 21(3):359-63. PMID: 19482462.
      Citations: 21     Fields:    Translation:HumansCells
    61. Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. J Neurosci. 2009 Feb 18; 29(7):1962-76. PMID: 19228951; PMCID: PMC2803056.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    62. Chatterjee S, Sang TK, Lawless GM, Jackson GR. Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model. Hum Mol Genet. 2009 Jan 01; 18(1):164-77. PMID: 18930955; PMCID: PMC2644648.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    63. Schaffer BA, Bertram L, Miller BL, Mullin K, Weintraub S, Johnson N, Bigio EH, Mesulam M, Wiedau-Pazos M, Jackson GR, Cummings JL, Cantor RM, Levey AI, Tanzi RE, Geschwind DH. Association of GSK3B with Alzheimer disease and frontotemporal dementia. Arch Neurol. 2008 Oct; 65(10):1368-74. PMID: 18852354; PMCID: PMC2841136.
      Citations: 33     Fields:    Translation:HumansCells
    64. Ratnaparkhi A, Lawless GM, Schweizer FE, Golshani P, Jackson GR. A Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanism. PLoS One. 2008 Jun 04; 3(6):e2334. PMID: 18523548; PMCID: PMC2390852.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    65. Jackson GR. Guide to understanding Drosophila models of neurodegenerative diseases. PLoS Biol. 2008 Feb; 6(2):e53. PMID: 18303955; PMCID: PMC2253643.
      Citations: 5     Fields:    Translation:HumansAnimals
    66. Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR. A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci. 2007 Jan 31; 27(5):981-92. PMID: 17267552; PMCID: PMC6673194.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    67. Sengupta S, Horowitz PM, Karsten SL, Jackson GR, Geschwind DH, Fu Y, Berry RW, Binder LI. Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 2006 Dec 19; 45(50):15111-9. PMID: 17154549.
      Citations: 34     Fields:    Translation:HumansCells
    68. Slepko N, Bhattacharyya AM, Jackson GR, Steffan JS, Marsh JL, Thompson LM, Wetzel R. Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14367-72. PMID: 16980414; PMCID: PMC1599969.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    69. Karsten SL, Sang TK, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Hui KS, Wiedau-Pazos M, Vinters HV, Binder LI, Geschwind DH, Jackson GR. A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron. 2006 Sep 07; 51(5):549-60. PMID: 16950154.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    70. Sang TK, Jackson GR. Drosophila models of neurodegenerative disease. NeuroRx. 2005 Jul; 2(3):438-46. PMID: 16389307; PMCID: PMC1144487.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    71. Mee L, Honkala H, Kopra O, Vesa J, Sang TK, Jackson GR, Salonen R, Peltonen L, Finnil? S, Visap?? I, Kestil? M. Hydrolethalus syndrome is caused by a missense mutation in a novel gene HYLS1. Hum Mol Genet. 2005 Jun 01; 14(11):1475-88. PMID: 15843405.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    72. Sang TK, Li C, Liu W, Rodriguez A, Abrams JM, Zipursky SL, Jackson GR. Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. Hum Mol Genet. 2005 Feb 01; 14(3):357-72. PMID: 15590702.
      Citations: 27     Fields:    Translation:HumansAnimals
    73. Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature. 2001 Oct 18; 413(6857):739-43. PMID: 11607033.
      Citations: 424     Fields:    Translation:AnimalsCells
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