Mitogen-Activated Protein Kinase Phosphatases
"Mitogen-Activated Protein Kinase Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subcategory of phosphohydrolases that are specific for MITOGEN-ACTIVATED PROTEIN KINASES. They play a role in the inactivation of the MAP KINASE SIGNALING SYSTEM.
| Descriptor ID |
D054639
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| MeSH Number(s) |
D08.811.277.352.650.587 D12.644.360.445 D12.776.476.445
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase Phosphatases".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase Phosphatases" by people in this website by year, and whether "Mitogen-Activated Protein Kinase Phosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 2 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase Phosphatases" by people in Profiles.
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DUSP22 rearrangement is associated with a distinctive immunophenotype but not outcome in patients with systemic ALK-negative anaplastic large cell lymphoma. Haematologica. 2023 06 01; 108(6):1604-1615.
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Lymphomatoid papulosis with DUSP22-IRF4 rearrangement: A case report and literature review. J Cutan Pathol. 2023 Aug; 50(8):711-716.
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Fragment-based design, synthesis, biological evaluation, and SAR of 1H-benzo[d]imidazol-2-yl)-1H-indazol derivatives as potent PDK1 inhibitors. Bioorg Med Chem Lett. 2017 12 15; 27(24):5473-5480.
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Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis. Oncotarget. 2016 Sep 06; 7(36):57593-57605.
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Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion. Breast Cancer Res Treat. 2016 08; 158(3):441-54.
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TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity. Cell Signal. 2016 Jan; 28(1):145-51.
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NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis. Cell Death Dis. 2015 Aug 06; 6:e1841.
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NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1a-stimulated angiogenesis. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2023-32.
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Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. Carcinogenesis. 2013 Apr; 34(4):885-92.
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Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance. Nat Med. 2012 Jul; 18(7):1052-9.