Dose-Response Relationship, Drug
"Dose-Response Relationship, Drug" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Descriptor ID |
D004305
|
MeSH Number(s) |
G07.690.773.875 G07.690.936.500
|
Concept/Terms |
Dose-Response Relationship, Drug- Dose-Response Relationship, Drug
- Dose-Response Relationships, Drug
- Drug Dose-Response Relationship
- Drug Dose-Response Relationships
- Relationship, Drug Dose-Response
- Relationships, Drug Dose-Response
- Dose Response Relationship, Drug
|
Below are MeSH descriptors whose meaning is more general than "Dose-Response Relationship, Drug".
Below are MeSH descriptors whose meaning is more specific than "Dose-Response Relationship, Drug".
This graph shows the total number of publications written about "Dose-Response Relationship, Drug" by people in this website by year, and whether "Dose-Response Relationship, Drug" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 50 | 50 |
1995 | 1 | 45 | 46 |
1996 | 0 | 41 | 41 |
1997 | 0 | 42 | 42 |
1998 | 0 | 63 | 63 |
1999 | 0 | 83 | 83 |
2000 | 0 | 81 | 81 |
2001 | 0 | 78 | 78 |
2002 | 0 | 89 | 89 |
2003 | 0 | 161 | 161 |
2004 | 0 | 159 | 159 |
2005 | 1 | 158 | 159 |
2006 | 1 | 122 | 123 |
2007 | 3 | 141 | 144 |
2008 | 0 | 143 | 143 |
2009 | 1 | 128 | 129 |
2010 | 2 | 122 | 124 |
2011 | 2 | 118 | 120 |
2012 | 0 | 98 | 98 |
2013 | 3 | 102 | 105 |
2014 | 1 | 122 | 123 |
2015 | 3 | 105 | 108 |
2016 | 0 | 81 | 81 |
2017 | 0 | 97 | 97 |
2018 | 3 | 86 | 89 |
2019 | 1 | 72 | 73 |
2020 | 1 | 59 | 60 |
2021 | 2 | 62 | 64 |
2022 | 0 | 8 | 8 |
2023 | 0 | 4 | 4 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dose-Response Relationship, Drug" by people in Profiles.
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A generalized phase 1-2-3 design integrating dose optimization with confirmatory treatment comparison. Biometrics. 2024 Jan 29; 80(1).
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Routine Monitoring of QTc Interval as a Barrier for Efficient Use of Methadone in Palliative Care. J Pain Symptom Manage. 2024 Feb; 67(2):e147-e150.
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Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, and clinical activity of OBI-3424 in patients with advanced or metastatic solid tumors. Br J Cancer. 2023 08; 129(2):266-274.
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Generalized phase I-II designs to increase long term therapeutic success rate. Pharm Stat. 2023 Jul-Aug; 22(4):692-706.
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Safety and Tolerability of Serdexmethylphenidate/Dexmethylphenidate Capsules in Children with Attention-Deficit/Hyperactivity Disorder: A 12-Month, Open-Label Safety Study. J Child Adolesc Psychopharmacol. 2023 03; 33(2):51-58.
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AIDE: Adaptive intrapatient dose escalation designs to accelerate Phase I clinical trials. Pharm Stat. 2023 03; 22(2):300-311.
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First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors. Invest New Drugs. 2022 10; 40(5):1001-1010.
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A semi-mechanistic dose-finding design in oncology using pharmacokinetic/pharmacodynamic modeling. Pharm Stat. 2022 11; 21(6):1149-1166.
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Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies. Elife. 2022 02 22; 11.
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TITE-BOIN12: A Bayesian phase I/II trial design to find the optimal biological dose with late-onset toxicity and efficacy. Stat Med. 2022 05 20; 41(11):1918-1931.