Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
"Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors that bind and internalize the granulocyte-macrophage stimulating factor. Their MW is believed to be 84 kD. The most mature myelomonocytic cells, specifically human neutrophils, macrophages, and eosinophils, express the highest number of affinity receptors for this growth factor.
| Descriptor ID |
D016187
|
| MeSH Number(s) |
D12.776.543.750.705.852.150.310 D12.776.543.750.750.400.200.420
|
| Concept/Terms |
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
- Receptors, Granulocyte Macrophage Colony Stimulating Factor
- Receptors, GM-CSF
- Receptors, GM CSF
- GM-CSF Receptors
- GM CSF Receptors
- CD116 Antigens
- CD116 Antigen
- Antigen, CD116
- Antigens, CD116
- GM-CSF Receptor
- GM CSF Receptor
- Receptor, GM-CSF
- Receptor, Granulocyte-Macrophage Colony-Stimulating Factor
- Receptor, Granulocyte Macrophage Colony Stimulating Factor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor [D12.776.543.750.705.852.150.310]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor [D12.776.543.750.750.400.200.420]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1996 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" by people in Profiles.
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A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer Discov. 2021 07; 11(7):1661-1671.
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Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R. J Med Chem. 2020 09 10; 63(17):9888-9911.
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CSF-1/CSF-1R axis is associated with epithelial/mesenchymal hybrid phenotype in epithelial-like inflammatory breast cancer. Sci Rep. 2018 06 21; 8(1):9427.
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The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science. 2016 May 20; 352(6288):aad3018.
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Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study. Neuro Oncol. 2016 Apr; 18(4):557-64.
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STAT3-activated GM-CSFRa translocates to the nucleus and protects CLL cells from apoptosis. Mol Cancer Res. 2014 Sep; 12(9):1267-82.
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Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia. Blood. 2010 Dec 23; 116(26):5991-6002.
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Immune dysregulation in the pathogenesis of pulmonary alveolar proteinosis. Curr Allergy Asthma Rep. 2010 Sep; 10(5):320-5.
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Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1. J Exp Med. 2008 Nov 24; 205(12):2711-6.
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Autosomal telomere exchange results in the rapid amplification and dispersion of Csf2ra genes in wild-derived mice. Mamm Genome. 2001 Dec; 12(12):882-6.