Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
|
| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
|
| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 2 | 6 | 8 |
| 1996 | 6 | 5 | 11 |
| 1997 | 7 | 7 | 14 |
| 1998 | 7 | 3 | 10 |
| 1999 | 8 | 4 | 12 |
| 2000 | 3 | 10 | 13 |
| 2001 | 5 | 1 | 6 |
| 2002 | 7 | 10 | 17 |
| 2003 | 15 | 6 | 21 |
| 2004 | 12 | 7 | 19 |
| 2005 | 8 | 13 | 21 |
| 2006 | 8 | 13 | 21 |
| 2007 | 8 | 7 | 15 |
| 2008 | 9 | 8 | 17 |
| 2009 | 3 | 6 | 9 |
| 2010 | 6 | 10 | 16 |
| 2011 | 13 | 10 | 23 |
| 2012 | 2 | 7 | 9 |
| 2013 | 8 | 6 | 14 |
| 2014 | 8 | 7 | 15 |
| 2015 | 5 | 6 | 11 |
| 2016 | 2 | 4 | 6 |
| 2017 | 4 | 4 | 8 |
| 2018 | 1 | 2 | 3 |
| 2019 | 2 | 1 | 3 |
| 2020 | 3 | 3 | 6 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 3 | 3 |
| 2023 | 2 | 2 | 4 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance. Dis Model Mech. 2023 08 01; 16(8).
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Hormonal changes in veterans with Gulf War Illness. Life Sci. 2023 Sep 01; 328:121908.
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Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs. eNeuro. 2023 04; 10(4).
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Pilot clinical trial of macimorelin to assess safety and efficacy in patients with cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 04; 14(2):835-846.
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Subtype of Neuroblastoma Cells with High KIT Expression Are Dependent on KIT and Its Knockdown Induces Compensatory Activation of Pro-Survival Signaling. Int J Mol Sci. 2022 Jul 13; 23(14).
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A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms in a murine model. Ann Neurol. 2022 07; 92(1):45-60.
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FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth. Endocrinology. 2022 02 01; 163(2).
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The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1. J Biol Chem. 2021 Jan-Jun; 296:100739.
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Cell-type specific analysis of physiological action of estrogen in mouse oviducts. FASEB J. 2021 05; 35(5):e21563.
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Inhibition of G Protein-Coupled Receptor Kinase 2 Promotes Unbiased Downregulation of IGF1 Receptor and Restrains Malignant Cell Growth. Cancer Res. 2021 01 15; 81(2):501-514.