"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Descriptor ID |
D007328
|
MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 7 | 3 | 10 |
1995 | 8 | 9 | 17 |
1996 | 9 | 7 | 16 |
1997 | 4 | 10 | 14 |
1998 | 6 | 4 | 10 |
1999 | 9 | 6 | 15 |
2000 | 5 | 8 | 13 |
2001 | 6 | 10 | 16 |
2002 | 7 | 18 | 25 |
2003 | 9 | 14 | 23 |
2004 | 18 | 13 | 31 |
2005 | 16 | 21 | 37 |
2006 | 16 | 23 | 39 |
2007 | 12 | 17 | 29 |
2008 | 17 | 13 | 30 |
2009 | 14 | 26 | 40 |
2010 | 13 | 18 | 31 |
2011 | 14 | 29 | 43 |
2012 | 20 | 21 | 41 |
2013 | 10 | 23 | 33 |
2014 | 8 | 17 | 25 |
2015 | 11 | 14 | 25 |
2016 | 14 | 21 | 35 |
2017 | 17 | 20 | 37 |
2018 | 7 | 19 | 26 |
2019 | 8 | 20 | 28 |
2020 | 7 | 18 | 25 |
2021 | 9 | 13 | 22 |
2022 | 2 | 27 | 29 |
2023 | 3 | 19 | 22 |
2024 | 0 | 4 | 4 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Increased Plasma Branched Short-Chain Fatty Acids and Improved Glucose Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES). Diabetes. 2024 Mar 01; 73(3):385-390.
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Osteocalcin protects islet identity in low-density lipoprotein receptor knockout mice on high-fat diet. J Endocrinol. 2024 Apr 01; 261(1).
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AIns (insulin) type amyloidoma of the extremity diagnosed by fine-needle aspiration. Diagn Cytopathol. 2024 May; 52(5):E116-E119.
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Adverse Metabolic Phenotypes in Parenterally Fed Neonatal Pigs Do Not Persist into Adolescence. J Nutr. 2024 02; 154(2):638-647.
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Leptin Decreases Gluconeogenesis and Gluconeogenic Substrate Availability in Patients With Lipodystrophy. J Clin Endocrinol Metab. 2023 Dec 21; 109(1):e209-e215.
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A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques. Diabetes. 2023 Dec 01; 72(12):1766-1780.
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Two Years with a Tubeless Automated Insulin Delivery System: A Single-Arm Multicenter Trial in Children, Adolescents, and Adults with Type 1 Diabetes. Diabetes Technol Ther. 2024 Jan; 26(1):11-23.
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Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection. Nat Commun. 2023 Nov 22; 14(1):7630.
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Amino acid-stimulated insulin secretion: a path forward in type 2 diabetes. Amino Acids. 2023 Dec; 55(12):1857-1866.
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Gastrointestinal Infections Modulate the Risk for Insulin Autoantibodies as the First-Appearing Autoantibody in the TEDDY Study. Diabetes Care. 2023 11 01; 46(11):1908-1915.